How to add annotations to a vcf file?


#1

Hello everyone,

I am trying to annotate my vcf file with exonic function, frequencies in GnomAD, and functional prediction scores. I am wondering if there is a way to do it in hail 0.2 version.
Any help would be appreciated.

Thanks in advance.


#2

exonic function…and functional prediction scores

You’ll want VEP. It sounds like you’ve figured this out based on Zulip.

frequencies in GnomAD

If you’re running on gcloud, you can use the release files in Hail format provided here:
http://gnomad.broadinstitute.org/downloads