# Case-control imbalance

**URL:** https://discuss.hail.is/t/case-control-imbalance/3000
**Category:** Science
**Created:** [December 19, 2022, 6:45pm UTC](https://discuss.hail.is/t/case-control-imbalance/3000 "2022-12-19T18:45:08Z")
**Posts on this page:** 2
**Page:** 1

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### Author: ![nafizh](https://avatars.discourse-cdn.com/v4/letter/n/90db22/32.png) [@nafizh](https://discuss.hail.is/u/nafizh)
#### Post date: [December 19, 2022, 6:45pm UTC](https://discuss.hail.is/t/case-control-imbalance/3000/1 "2022-12-19T18:45:08Z")

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I have a dataset that is extremely imbalanced in the case:control ratio. Is there a way to correct for this in hail when running a gwas with the `logistic_regression_rows()` method? Thank you.

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### Author: ![danking](https://yyz2.discourse-cdn.com/flex036/user_avatar/discuss.hail.is/danking/32/43_2.png) [@danking](https://discuss.hail.is/u/danking)
#### Post date: [December 19, 2022, 7:56pm UTC](https://discuss.hail.is/t/case-control-imbalance/3000/2 "2022-12-19T19:56:55Z")

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Hail doesn’t have any sophisticated tools to address case-control imbalance. I think your best bet is using SAIGE to analyze your data.