# How to add annotations to a vcf file?

**URL:** <https://discuss.hail.is/t/how-to-add-annotations-to-a-vcf-file/735>\
**Category:** Hail Query & hailctl\
**Created:** [October 30, 2018, 10:30pm UTC](https://discuss.hail.is/t/how-to-add-annotations-to-a-vcf-file/735 "2018-10-30T22:30:31Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![Monica\_Sudarsanam](https://avatars.discourse-cdn.com/v4/letter/m/3be4f8/32.png) [@Monica\_Sudarsanam](https://discuss.hail.is/u/Monica_Sudarsanam)\
**Post date:** [October 30, 2018, 10:30pm UTC](https://discuss.hail.is/t/how-to-add-annotations-to-a-vcf-file/735/1 "2018-10-30T22:30:31Z")

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Hello everyone,

I am trying to annotate my vcf file with exonic function, frequencies in GnomAD, and functional prediction scores. I am wondering if there is a way to do it in hail 0.2 version.  
Any help would be appreciated.

Thanks in advance.

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**Author:** ![tpoterba](https://yyz2.discourse-cdn.com/flex036/user_avatar/discuss.hail.is/tpoterba/32/61_2.png) [@tpoterba](https://discuss.hail.is/u/tpoterba)\
**Post date:** [October 31, 2018, 12:59am UTC](https://discuss.hail.is/t/how-to-add-annotations-to-a-vcf-file/735/2 "2018-10-31T00:59:41Z")

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> exonic function…and functional prediction scores

You’ll want VEP. It sounds like you’ve figured this out based on Zulip.

> frequencies in GnomAD

If you’re running on gcloud, you can use the release files in Hail format provided here:

> **[gnomAD](https://gnomad.broadinstitute.org/downloads)**
>
> The Genome Aggregation Database (gnomAD) is a resource developed by an international coalition of investigators, with the goal of aggregating and harmonizing both exome and genome sequencing data from a wide variety of large-scale sequencing...
