# Implement Regenie

**URL:** https://discuss.hail.is/t/implement-regenie/2168
**Category:** Feature Requests
**Created:** [August 4, 2021, 6:33am UTC](https://discuss.hail.is/t/implement-regenie/2168 "2021-08-04T06:33:58Z")
**Posts on this page:** 4
**Page:** 1

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### Author: ![inninun](https://avatars.discourse-cdn.com/v4/letter/i/f17d59/32.png) [@inninun](https://discuss.hail.is/u/inninun)
#### Post date: [August 4, 2021, 6:33am UTC](https://discuss.hail.is/t/implement-regenie/2168/1 "2021-08-04T06:33:58Z")

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Hi Hail team,

Regenie is for the gene/region-based burden test and it works on both quantitative and binary traits.  
It would be very useful for whole-genome regression modeling. I would be very happy if Regenie could be used in Hail.

Mbatchou, J., Barnard, L., Backman, J. et al. Computationally efficient whole-genome regression for quantitative and binary traits. Nat Genet 53, 1097–1103 (2021). [Computationally efficient whole-genome regression for quantitative and binary traits | Nature Genetics](https://doi.org/10.1038/s41588-021-00870-7)

[https://rgcgithub.github.io/regenie/](https://rgcgithub.github.io/regenie/)

Thanks,  
minyoung

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### Author: ![olszewskip](https://avatars.discourse-cdn.com/v4/letter/o/f1d935/32.png) [@olszewskip](https://discuss.hail.is/u/olszewskip)
#### Post date: [August 5, 2021, 8:00pm UTC](https://discuss.hail.is/t/implement-regenie/2168/2 "2021-08-05T20:00:22Z")

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Hi!  
A sidenote: You may be interested in [GloWGR: Whole Genome Regression — Glow documentation](https://glow.readthedocs.io/en/latest/tertiary/whole-genome-regression.html)

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### Author: ![johnc1231](https://yyz2.discourse-cdn.com/flex036/user_avatar/discuss.hail.is/johnc1231/32/286_2.png) [@johnc1231](https://discuss.hail.is/u/johnc1231)
#### Post date: [August 5, 2021, 9:07pm UTC](https://discuss.hail.is/t/implement-regenie/2168/3 "2021-08-05T21:07:43Z")

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We are definitely aware of Regenie and it is something we are looking into adding support for, but don’t have any clear plans / timelines yet.

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### Author: ![inninun](https://avatars.discourse-cdn.com/v4/letter/i/f17d59/32.png) [@inninun](https://discuss.hail.is/u/inninun)
#### Post date: [August 26, 2021, 7:07am UTC](https://discuss.hail.is/t/implement-regenie/2168/4 "2021-08-26T07:07:56Z")

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Thank you for your answer!
