# Logistic mixed-effects model
**URL:** https://discuss.hail.is/t/logistic-mixed-effects-model/384
**Category:** Feature Requests
**Created:** [December 19, 2017, 8:03pm UTC](https://discuss.hail.is/t/logistic-mixed-effects-model/384 "2017-12-19T20:03:41Z")
**Posts on this page:** 2
**Page:** 1
### Author:  [@tpoterba](https://discuss.hail.is/u/tpoterba)
#### Post date: [December 19, 2017, 8:03pm UTC](https://discuss.hail.is/t/logistic-mixed-effects-model/384/1 "2017-12-19T20:03:41Z")
Seung Hoan mentioned this as a useful method to add:
> **[Efficiently controlling for case-control imbalance and sample relatedness in...](https://www.biorxiv.org/content/10.1101/212357v3)**
>
> In genome-wide association studies (GWAS) for thousands of phenotypes in large biobanks, most binary traits have substantially fewer cases than controls. Both of the widely used approaches, linear mixed model and the recently proposed logistic mixed...
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### Author:  [@Stephane\_Bourgeois](https://discuss.hail.is/u/Stephane_Bourgeois)
#### Post date: [January 9, 2018, 5:14pm UTC](https://discuss.hail.is/t/logistic-mixed-effects-model/384/2 "2018-01-09T17:14:03Z")
Both this new method and the logistic mixed models would be of great interest.