# What is the setup required to perform annotations using vep? **URL:** \ **Category:** Hail Query & hailctl\ **Created:** [October 30, 2018, 10:37pm UTC](https://discuss.hail.is/t/what-is-the-setup-required-to-perform-annotations-using-vep/736 "2018-10-30T22:37:38Z")\ **Posts on this page:** 1\ **Page:** 1
**Author:** ![Monica\_Sudarsanam](https://avatars.discourse-cdn.com/v4/letter/m/3be4f8/32.png) [@Monica\_Sudarsanam](https://discuss.hail.is/u/Monica_Sudarsanam)\ **Post date:** [October 30, 2018, 10:37pm UTC](https://discuss.hail.is/t/what-is-the-setup-required-to-perform-annotations-using-vep/736/1 "2018-10-30T22:37:38Z")
Hello everyone, I am trying to add annotations to my vcf file using vep. I used the following line to configure vep while creating my cluster on google cloud ( I am using windows 10) **–initialization-actions “gs://dataproc-initialization-actions/jupyter/jupyter.sh,gs://dataproc-initialization-actions/conda/bootstrap-conda.sh,gs://hail-common/cloudtools/init\_notebook1.py,gs://hail-common/vep/vep/vep85-init.sh” ^** And i used the following line to add annotations to my vcf file **result = hl.vep(vcf\_file, “gs://hail-common/vep/vep/vep85-gcloud.json”)** Then i received following error while trying to export the data. I am wondering if i need any additional setup for vep. Thanks in advance. **Hail version: devel-0643c11962e8** **Error summary: HailException: vep command ‘/usr/bin/perl /vep/variant\_effect\_predictor/variant\_effect\_predictor.pl --format vcf --json --everything --allele\_number --no\_stats --cache --offline --dir /vep --fasta /vep/homo\_sapiens/85\_GRCh37/Homo\_sapiens.GRCh37.75.dna.primary\_assembly.fa --minimal --assembly GRCh37 --plugin LoF,human\_ancestor\_fa:/vep/loftee\_data/human\_ancestor.fa.gz,filter\_position:0.05,min\_intron\_size:15,conservation\_file:/vep/loftee\_data/phylocsf.sql -o STDOUT’ failed with non-zero exit status 2**