2022-04-01 03:24:56 Hail: INFO: Running Hail version 0.2.57-582b2e31b8bd 2022-04-01 03:24:56 SparkContext: WARN: Using an existing SparkContext; some configuration may not take effect. 2022-04-01 03:24:57 root: INFO: RegionPool: initialized for thread 18: Thread-6 2022-04-01 03:24:57 MemoryStore: INFO: Block broadcast_0 stored as values in memory (estimated size 323.9 KB, free 5.6 GB) 2022-04-01 03:24:57 YarnSchedulerBackend$YarnDriverEndpoint: INFO: Registered executor NettyRpcEndpointRef(spark-client://Executor) (172.23.75.58:51560) with ID 1 2022-04-01 03:24:57 ExecutorAllocationManager: INFO: New executor 1 has registered (new total is 1) 2022-04-01 03:24:57 BlockManagerMasterEndpoint: INFO: Registering block manager ip-172-23-75-58.ec2.internal:40133 with 181.7 GB RAM, BlockManagerId(1, ip-172-23-75-58.ec2.internal, 40133, None) 2022-04-01 03:24:57 MemoryStore: INFO: Block broadcast_0_piece0 stored as bytes in memory (estimated size 29.9 KB, free 5.6 GB) 2022-04-01 03:24:57 BlockManagerInfo: INFO: Added broadcast_0_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 29.9 KB, free: 5.6 GB) 2022-04-01 03:24:57 SparkContext: INFO: Created broadcast 0 from broadcast at SparkBackend.scala:233 2022-04-01 03:24:58 ClientConfigurationFactory: INFO: Set initial getObject socket timeout to 2000 ms. 2022-04-01 03:24:59 YarnSchedulerBackend$YarnDriverEndpoint: INFO: Registered executor NettyRpcEndpointRef(spark-client://Executor) (172.23.70.80:46798) with ID 2 2022-04-01 03:24:59 ExecutorAllocationManager: INFO: New executor 2 has registered (new total is 2) 2022-04-01 03:24:59 BlockManagerMasterEndpoint: INFO: Registering block manager ip-172-23-70-80.ec2.internal:37501 with 181.7 GB RAM, BlockManagerId(2, ip-172-23-70-80.ec2.internal, 37501, None) 2022-04-01 03:24:59 root: INFO: globbing path s3://seqr-dp-data--prod/vcf/prod/IUIS_PANELv1_20220321.vcf.gz returned 1 files: IUIS_PANELv1_20220321.vcf.gz 2022-04-01 03:24:59 root: INFO: globbing path s3://seqr-dp-data--prod/vcf/prod/IUIS_PANELv1_20220321.vcf.gz returned 1 files: IUIS_PANELv1_20220321.vcf.gz 2022-04-01 03:24:59 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/vcf/prod/IUIS_PANELv1_20220321.vcf.gz' for reading 2022-04-01 03:25:00 MemoryStore: INFO: Block broadcast_1 stored as values in memory (estimated size 1699.1 KB, free 5.6 GB) 2022-04-01 03:25:00 MemoryStore: INFO: Block broadcast_1_piece0 stored as bytes in memory (estimated size 123.7 KB, free 5.6 GB) 2022-04-01 03:25:00 BlockManagerInfo: INFO: Added broadcast_1_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 123.7 KB, free: 5.6 GB) 2022-04-01 03:25:00 SparkContext: INFO: Created broadcast 1 from broadcast at SparkBackend.scala:233 2022-04-01 03:25:00 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/vep99/vep99-loftee-grch38-aws.json' for reading 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- Verify : 4.121ms, total 25.083ms 2022-04-01 03:25:01 root: INFO: optimize optimize: legacyRelationalLowerer, initial IR: before: IR size 42: (TableToTableApply "{\"config\":\"s3://seqr-dp-data--prod/vep99/vep99-loftee-grch38-aws.json\",\"csq\":false,\"blockSize\":1000,\"name\":\"VEP\"}" (MatrixRowsTable (MatrixMapRows (MatrixMapGlobals (MatrixKeyRowsBy (locus alleles) False (MatrixMapRows (MatrixKeyRowsBy () False (MatrixMapRows (MatrixMapRows (MatrixRead None False False "{\"files\":[\"s3://seqr-dp-data--prod/vcf/prod/IUIS_PANELv1_20220321.vcf.gz\"],\"callFields\":[\"PGT\"],\"entryFloatTypeName\":\"Float64\",\"minPartitions\":500,\"rg\":\"GRCh38\",\"contigRecoding\":{},\"arrayElementsRequired\":false,\"skipInvalidLoci\":false,\"gzAsBGZ\":true,\"forceGZ\":false,\"filterAndReplace\":{},\"partitionsJSON\":null,\"name\":\"MatrixVCFReader\"}") (InsertFields (SelectFields (locus alleles rsid qual filters info) (Ref va)) None (a_index (I32 1)))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index) (Ref va)) None (alleles_old (GetField alleles (Ref va))) (locus_old (GetField locus (Ref va)))))) (Let __uid_3 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (Ref va)) (GetField alleles (Ref va))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old) (Ref va)) None (locus (GetField locus (Ref __uid_3))) (alleles (GetField alleles (Ref __uid_3))))))) (InsertFields (SelectFields () (Ref global)) None (gencodeVersion (Str "25")))) (InsertFields (SelectFields (locus alleles) (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old) (Ref va))) None)))) 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 7.047ms, total 66.973ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 14.059ms, total 81.661ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 47.113ms, total 129.909ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 7.456ms, total 137.858ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 1.871ms, total 140.327ms 2022-04-01 03:25:01 root: INFO: Prune: InsertFields: eliminating field 'a_index' 2022-04-01 03:25:01 root: INFO: Prune: InsertFields: eliminating field 'alleles_old' 2022-04-01 03:25:01 root: INFO: Prune: InsertFields: eliminating field 'locus_old' 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 40.873ms, total 181.657ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.653ms, total 182.633ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.543ms, total 183.476ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 3.774ms, total 187.452ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 3.729ms, total 191.399ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.199ms, total 191.823ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 6.915ms, total 198.908ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.381ms, total 199.485ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.269ms, total 199.947ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.487ms, total 200.611ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 8.230ms, total 209.040ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.170ms, total 209.428ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.761ms, total 212.360ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation -- Optimize : 152.990ms, total 212.565ms, tagged coverage 95.8 2022-04-01 03:25:01 root: INFO: optimize optimize: legacyRelationalLowerer, initial IR: after: IR size 22: (TableToTableApply "{\"config\":\"s3://seqr-dp-data--prod/vep99/vep99-loftee-grch38-aws.json\",\"csq\":false,\"blockSize\":1000,\"name\":\"VEP\"}" (TableMapGlobals (TableKeyBy (locus alleles) False (MatrixRowsTable (MatrixMapRows (MatrixKeyRowsBy () False (MatrixRead Matrix{global:Struct{},col_key:[s],col:Struct{s:String},row_key:[[locus,alleles]],row:Struct{locus:Locus(GRCh38),alleles:Array[String]},entry:Struct{}} False False "{\"files\":[\"s3://seqr-dp-data--prod/vcf/prod/IUIS_PANELv1_20220321.vcf.gz\"],\"callFields\":[\"PGT\"],\"entryFloatTypeName\":\"Float64\",\"minPartitions\":500,\"rg\":\"GRCh38\",\"contigRecoding\":{},\"arrayElementsRequired\":false,\"skipInvalidLoci\":false,\"gzAsBGZ\":true,\"forceGZ\":false,\"filterAndReplace\":{},\"partitionsJSON\":null,\"name\":\"MatrixVCFReader\"}")) (Let __iruid_6 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (Ref va)) (GetField alleles (Ref va))) (InsertFields (Ref va) None (locus (GetField locus (Ref __iruid_6))) (alleles (GetField alleles (Ref __iruid_6)))))))) (InsertFields (Ref global) None (gencodeVersion (Str "25"))))) 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- LoweringTransformation : 190.066ms, total 217.055ms, tagged coverage 77.1 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR -- Verify : 0.056ms, total 217.566ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, initial IR : 197.073ms, total 217.741ms, tagged coverage 76.5 2022-04-01 03:25:01 root: INFO: Timer: Time taken for LowerMatrixToTable -- Verify : 0.030ms, total 231.846ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for LowerMatrixToTable -- LoweringTransformation : 13.801ms, total 245.851ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for LowerMatrixToTable -- Verify : 0.354ms, total 246.452ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for LowerMatrixToTable : 14.807ms, total 246.618ms, tagged coverage 95.8 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- Verify : 0.045ms, total 248.573ms 2022-04-01 03:25:01 root: INFO: optimize optimize: legacyRelationalLowerer, after LowerMatrixToTable: before: IR size 39: (TableToTableApply "{\"config\":\"s3://seqr-dp-data--prod/vep99/vep99-loftee-grch38-aws.json\",\"csq\":false,\"blockSize\":1000,\"name\":\"VEP\"}" (TableMapGlobals (TableKeyBy (locus alleles) False (TableMapRows (TableMapGlobals (TableMapRows (TableKeyBy () False (TableRead Table{global:Struct{__cols:Array[Struct{s:String}]},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{}]}} False "{\"files\":[\"s3://seqr-dp-data--prod/vcf/prod/IUIS_PANELv1_20220321.vcf.gz\"],\"callFields\":[\"PGT\"],\"entryFloatTypeName\":\"Float64\",\"minPartitions\":500,\"rg\":\"GRCh38\",\"contigRecoding\":{},\"arrayElementsRequired\":false,\"skipInvalidLoci\":false,\"gzAsBGZ\":true,\"forceGZ\":false,\"filterAndReplace\":{},\"partitionsJSON\":null,\"name\":\"MatrixVCFReader\"}")) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_7 (MakeStruct) (Let __iruid_6 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (SelectFields (locus alleles) (Ref row))) (GetField alleles (SelectFields (locus alleles) (Ref row)))) (InsertFields (SelectFields (locus alleles) (Ref row)) None (locus (GetField locus (Ref __iruid_6))) (alleles (GetField alleles (Ref __iruid_6)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (SelectFields () (Ref global))) (SelectFields (locus alleles) (Ref row)))) (InsertFields (Ref global) None (gencodeVersion (Str "25"))))) 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- FoldConstants : 3.225ms, total 254.674ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.406ms, total 255.238ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- Simplify : 0.940ms, total 256.323ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ForwardLets : 5.934ms, total 262.395ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.148ms, total 262.718ms 2022-04-01 03:25:01 root: INFO: Prune: InsertFields: eliminating field 'the entries! [877f12a8827e18f61222c6c8c5fb04a8]' 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- PruneDeadFields : 3.563ms, total 266.397ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- FoldConstants : 0.506ms, total 267.100ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.470ms, total 267.751ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- Simplify : 3.696ms, total 271.623ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ForwardLets : 2.238ms, total 274.045ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.182ms, total 274.423ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.109ms, total 276.713ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- FoldConstants : 0.306ms, total 277.202ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.257ms, total 277.624ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- Simplify : 0.331ms, total 278.122ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ForwardLets : 2.092ms, total 280.380ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.160ms, total 280.747ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.065ms, total 282.993ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize : 31.715ms, total 283.160ms, tagged coverage 90.3 2022-04-01 03:25:01 root: INFO: optimize optimize: legacyRelationalLowerer, after LowerMatrixToTable: after: IR size 21: (TableToTableApply "{\"config\":\"s3://seqr-dp-data--prod/vep99/vep99-loftee-grch38-aws.json\",\"csq\":false,\"blockSize\":1000,\"name\":\"VEP\"}" (TableMapGlobals (TableKeyBy (locus alleles) False (TableMapRows (TableKeyBy () False (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String]}} False "{\"files\":[\"s3://seqr-dp-data--prod/vcf/prod/IUIS_PANELv1_20220321.vcf.gz\"],\"callFields\":[\"PGT\"],\"entryFloatTypeName\":\"Float64\",\"minPartitions\":500,\"rg\":\"GRCh38\",\"contigRecoding\":{},\"arrayElementsRequired\":false,\"skipInvalidLoci\":false,\"gzAsBGZ\":true,\"forceGZ\":false,\"filterAndReplace\":{},\"partitionsJSON\":null,\"name\":\"MatrixVCFReader\"}")) (Let __iruid_12 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (Ref row)) (GetField alleles (Ref row))) (InsertFields (Ref row) None (locus (GetField locus (Ref __iruid_12))) (alleles (GetField alleles (Ref __iruid_12))))))) (InsertFields (Ref global) None (gencodeVersion (Str "25"))))) 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- LoweringTransformation : 36.450ms, total 285.191ms, tagged coverage 78.5 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable -- Verify : 0.038ms, total 285.418ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LowerMatrixToTable : 37.021ms, total 285.545ms, tagged coverage 77.6 2022-04-01 03:25:01 root: INFO: Timer: Time taken for InterpretNonCompilable -- Verify : 0.040ms, total 286.113ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation : 2.051ms, total 288.320ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for InterpretNonCompilable -- Verify : 0.340ms, total 288.844ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for InterpretNonCompilable : 2.951ms, total 289.019ms, tagged coverage 82.4 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- Verify : 0.032ms, total 289.579ms 2022-04-01 03:25:01 root: INFO: optimize optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable: before: IR size 21: (TableToTableApply "{\"config\":\"s3://seqr-dp-data--prod/vep99/vep99-loftee-grch38-aws.json\",\"csq\":false,\"blockSize\":1000,\"name\":\"VEP\"}" (TableMapGlobals (TableKeyBy (locus alleles) False (TableMapRows (TableKeyBy () False (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String]}} False "{\"files\":[\"s3://seqr-dp-data--prod/vcf/prod/IUIS_PANELv1_20220321.vcf.gz\"],\"callFields\":[\"PGT\"],\"entryFloatTypeName\":\"Float64\",\"minPartitions\":500,\"rg\":\"GRCh38\",\"contigRecoding\":{},\"arrayElementsRequired\":false,\"skipInvalidLoci\":false,\"gzAsBGZ\":true,\"forceGZ\":false,\"filterAndReplace\":{},\"partitionsJSON\":null,\"name\":\"MatrixVCFReader\"}")) (Let __iruid_12 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (Ref row)) (GetField alleles (Ref row))) (InsertFields (Ref row) None (locus (GetField locus (Ref __iruid_12))) (alleles (GetField alleles (Ref __iruid_12))))))) (InsertFields (Ref global) None (gencodeVersion (Str "25"))))) 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- FoldConstants : 0.237ms, total 291.798ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.264ms, total 292.228ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- Simplify : 0.356ms, total 292.740ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- ForwardLets : 2.253ms, total 295.149ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.155ms, total 295.492ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.235ms, total 297.938ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- FoldConstants : 0.314ms, total 298.487ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 6.732ms, total 305.401ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- Simplify : 0.429ms, total 306.056ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- ForwardLets : 2.237ms, total 308.482ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.184ms, total 308.858ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.517ms, total 311.530ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- FoldConstants : 0.311ms, total 312.064ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.313ms, total 312.544ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- Simplify : 0.348ms, total 313.056ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- ForwardLets : 4.030ms, total 317.249ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.182ms, total 317.619ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.227ms, total 320.007ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation -- Optimize : 28.631ms, total 320.186ms, tagged coverage 88.4 2022-04-01 03:25:01 root: INFO: optimize optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable: after: IR size 21: (TableToTableApply "{\"config\":\"s3://seqr-dp-data--prod/vep99/vep99-loftee-grch38-aws.json\",\"csq\":false,\"blockSize\":1000,\"name\":\"VEP\"}" (TableMapGlobals (TableKeyBy (locus alleles) False (TableMapRows (TableKeyBy () False (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String]}} False "{\"files\":[\"s3://seqr-dp-data--prod/vcf/prod/IUIS_PANELv1_20220321.vcf.gz\"],\"callFields\":[\"PGT\"],\"entryFloatTypeName\":\"Float64\",\"minPartitions\":500,\"rg\":\"GRCh38\",\"contigRecoding\":{},\"arrayElementsRequired\":false,\"skipInvalidLoci\":false,\"gzAsBGZ\":true,\"forceGZ\":false,\"filterAndReplace\":{},\"partitionsJSON\":null,\"name\":\"MatrixVCFReader\"}")) (Let __iruid_15 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (Ref row)) (GetField alleles (Ref row))) (InsertFields (Ref row) None (locus (GetField locus (Ref __iruid_15))) (alleles (GetField alleles (Ref __iruid_15))))))) (InsertFields (Ref global) None (gencodeVersion (Str "25"))))) 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- LoweringTransformation : 32.680ms, total 322.491ms, tagged coverage 77.5 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable -- Verify : 0.037ms, total 322.739ms 2022-04-01 03:25:01 root: INFO: Timer: Time taken for optimize: legacyRelationalLowerer, after LegacyInterpretNonCompilable : 33.320ms, total 322.859ms, tagged coverage 76.2 2022-04-01 03:25:01 SparkContext: INFO: Starting job: runJob at ContextRDD.scala:228 2022-04-01 03:25:01 DAGScheduler: INFO: Got job 0 (runJob at ContextRDD.scala:228) with 500 output partitions 2022-04-01 03:25:01 DAGScheduler: INFO: Final stage: ResultStage 0 (runJob at ContextRDD.scala:228) 2022-04-01 03:25:01 DAGScheduler: INFO: Parents of final stage: List() 2022-04-01 03:25:01 DAGScheduler: INFO: Missing parents: List() 2022-04-01 03:25:01 DAGScheduler: INFO: Submitting ResultStage 0 (GenericTableValueRDD[1] at RDD at GenericTableValue.scala:83), which has no missing parents 2022-04-01 03:25:01 MemoryStore: INFO: Block broadcast_2 stored as values in memory (estimated size 28.5 KB, free 5.6 GB) 2022-04-01 03:25:01 MemoryStore: INFO: Block broadcast_2_piece0 stored as bytes in memory (estimated size 13.2 KB, free 5.6 GB) 2022-04-01 03:25:01 BlockManagerInfo: INFO: Added broadcast_2_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 13.2 KB, free: 5.6 GB) 2022-04-01 03:25:01 SparkContext: INFO: Created broadcast 2 from broadcast at DAGScheduler.scala:1280 2022-04-01 03:25:01 DAGScheduler: INFO: Submitting 500 missing tasks from ResultStage 0 (GenericTableValueRDD[1] at RDD at GenericTableValue.scala:83) (first 15 tasks are for partitions Vector(0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)) 2022-04-01 03:25:01 YarnScheduler: INFO: Adding task set 0.0 with 500 tasks 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 0.0 in stage 0.0 (TID 0, ip-172-23-70-80.ec2.internal, executor 2, partition 0, PROCESS_LOCAL, 8160 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 1.0 in stage 0.0 (TID 1, ip-172-23-75-58.ec2.internal, executor 1, partition 1, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 2.0 in stage 0.0 (TID 2, ip-172-23-70-80.ec2.internal, executor 2, partition 2, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 3.0 in stage 0.0 (TID 3, ip-172-23-75-58.ec2.internal, executor 1, partition 3, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 4.0 in stage 0.0 (TID 4, ip-172-23-70-80.ec2.internal, executor 2, partition 4, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 5.0 in stage 0.0 (TID 5, ip-172-23-75-58.ec2.internal, executor 1, partition 5, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 6.0 in stage 0.0 (TID 6, ip-172-23-70-80.ec2.internal, executor 2, partition 6, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 7.0 in stage 0.0 (TID 7, ip-172-23-75-58.ec2.internal, executor 1, partition 7, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 8.0 in stage 0.0 (TID 8, ip-172-23-70-80.ec2.internal, executor 2, partition 8, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 9.0 in stage 0.0 (TID 9, ip-172-23-75-58.ec2.internal, executor 1, partition 9, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 10.0 in stage 0.0 (TID 10, ip-172-23-70-80.ec2.internal, executor 2, partition 10, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 11.0 in stage 0.0 (TID 11, ip-172-23-75-58.ec2.internal, executor 1, partition 11, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 12.0 in stage 0.0 (TID 12, ip-172-23-70-80.ec2.internal, executor 2, partition 12, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 13.0 in stage 0.0 (TID 13, ip-172-23-75-58.ec2.internal, executor 1, partition 13, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 14.0 in stage 0.0 (TID 14, ip-172-23-70-80.ec2.internal, executor 2, partition 14, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 15.0 in stage 0.0 (TID 15, ip-172-23-75-58.ec2.internal, executor 1, partition 15, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 16.0 in stage 0.0 (TID 16, ip-172-23-70-80.ec2.internal, executor 2, partition 16, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 17.0 in stage 0.0 (TID 17, ip-172-23-75-58.ec2.internal, executor 1, partition 17, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 18.0 in stage 0.0 (TID 18, ip-172-23-70-80.ec2.internal, executor 2, partition 18, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 19.0 in stage 0.0 (TID 19, ip-172-23-75-58.ec2.internal, executor 1, partition 19, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 20.0 in stage 0.0 (TID 20, ip-172-23-70-80.ec2.internal, executor 2, partition 20, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 21.0 in stage 0.0 (TID 21, ip-172-23-75-58.ec2.internal, executor 1, partition 21, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 22.0 in stage 0.0 (TID 22, ip-172-23-70-80.ec2.internal, executor 2, partition 22, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 23.0 in stage 0.0 (TID 23, ip-172-23-75-58.ec2.internal, executor 1, partition 23, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 24.0 in stage 0.0 (TID 24, ip-172-23-70-80.ec2.internal, executor 2, partition 24, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 25.0 in stage 0.0 (TID 25, ip-172-23-75-58.ec2.internal, executor 1, partition 25, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 26.0 in stage 0.0 (TID 26, ip-172-23-70-80.ec2.internal, executor 2, partition 26, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 27.0 in stage 0.0 (TID 27, ip-172-23-75-58.ec2.internal, executor 1, partition 27, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 28.0 in stage 0.0 (TID 28, ip-172-23-70-80.ec2.internal, executor 2, partition 28, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 29.0 in stage 0.0 (TID 29, ip-172-23-75-58.ec2.internal, executor 1, partition 29, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 30.0 in stage 0.0 (TID 30, ip-172-23-70-80.ec2.internal, executor 2, partition 30, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 31.0 in stage 0.0 (TID 31, ip-172-23-75-58.ec2.internal, executor 1, partition 31, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 32.0 in stage 0.0 (TID 32, ip-172-23-70-80.ec2.internal, executor 2, partition 32, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 33.0 in stage 0.0 (TID 33, ip-172-23-75-58.ec2.internal, executor 1, partition 33, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 34.0 in stage 0.0 (TID 34, ip-172-23-70-80.ec2.internal, executor 2, partition 34, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 35.0 in stage 0.0 (TID 35, ip-172-23-75-58.ec2.internal, executor 1, partition 35, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 36.0 in stage 0.0 (TID 36, ip-172-23-70-80.ec2.internal, executor 2, partition 36, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 37.0 in stage 0.0 (TID 37, ip-172-23-75-58.ec2.internal, executor 1, partition 37, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 38.0 in stage 0.0 (TID 38, ip-172-23-70-80.ec2.internal, executor 2, partition 38, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 39.0 in stage 0.0 (TID 39, ip-172-23-75-58.ec2.internal, executor 1, partition 39, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 40.0 in stage 0.0 (TID 40, ip-172-23-70-80.ec2.internal, executor 2, partition 40, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 41.0 in stage 0.0 (TID 41, ip-172-23-75-58.ec2.internal, executor 1, partition 41, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 42.0 in stage 0.0 (TID 42, ip-172-23-70-80.ec2.internal, executor 2, partition 42, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 43.0 in stage 0.0 (TID 43, ip-172-23-75-58.ec2.internal, executor 1, partition 43, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 44.0 in stage 0.0 (TID 44, ip-172-23-70-80.ec2.internal, executor 2, partition 44, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 45.0 in stage 0.0 (TID 45, ip-172-23-75-58.ec2.internal, executor 1, partition 45, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 46.0 in stage 0.0 (TID 46, ip-172-23-70-80.ec2.internal, executor 2, partition 46, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 47.0 in stage 0.0 (TID 47, ip-172-23-75-58.ec2.internal, executor 1, partition 47, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 48.0 in stage 0.0 (TID 48, ip-172-23-70-80.ec2.internal, executor 2, partition 48, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 49.0 in stage 0.0 (TID 49, ip-172-23-75-58.ec2.internal, executor 1, partition 49, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 50.0 in stage 0.0 (TID 50, ip-172-23-70-80.ec2.internal, executor 2, partition 50, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 51.0 in stage 0.0 (TID 51, ip-172-23-75-58.ec2.internal, executor 1, partition 51, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 52.0 in stage 0.0 (TID 52, ip-172-23-70-80.ec2.internal, executor 2, partition 52, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 53.0 in stage 0.0 (TID 53, ip-172-23-75-58.ec2.internal, executor 1, partition 53, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 54.0 in stage 0.0 (TID 54, ip-172-23-70-80.ec2.internal, executor 2, partition 54, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 55.0 in stage 0.0 (TID 55, ip-172-23-75-58.ec2.internal, executor 1, partition 55, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 56.0 in stage 0.0 (TID 56, ip-172-23-70-80.ec2.internal, executor 2, partition 56, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 57.0 in stage 0.0 (TID 57, ip-172-23-75-58.ec2.internal, executor 1, partition 57, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 58.0 in stage 0.0 (TID 58, ip-172-23-70-80.ec2.internal, executor 2, partition 58, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 59.0 in stage 0.0 (TID 59, ip-172-23-75-58.ec2.internal, executor 1, partition 59, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 60.0 in stage 0.0 (TID 60, ip-172-23-70-80.ec2.internal, executor 2, partition 60, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 61.0 in stage 0.0 (TID 61, ip-172-23-75-58.ec2.internal, executor 1, partition 61, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 62.0 in stage 0.0 (TID 62, ip-172-23-70-80.ec2.internal, executor 2, partition 62, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 63.0 in stage 0.0 (TID 63, ip-172-23-75-58.ec2.internal, executor 1, partition 63, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 64.0 in stage 0.0 (TID 64, ip-172-23-70-80.ec2.internal, executor 2, partition 64, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 65.0 in stage 0.0 (TID 65, ip-172-23-75-58.ec2.internal, executor 1, partition 65, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 66.0 in stage 0.0 (TID 66, ip-172-23-70-80.ec2.internal, executor 2, partition 66, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 67.0 in stage 0.0 (TID 67, ip-172-23-75-58.ec2.internal, executor 1, partition 67, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 68.0 in stage 0.0 (TID 68, ip-172-23-70-80.ec2.internal, executor 2, partition 68, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 69.0 in stage 0.0 (TID 69, ip-172-23-75-58.ec2.internal, executor 1, partition 69, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 70.0 in stage 0.0 (TID 70, ip-172-23-70-80.ec2.internal, executor 2, partition 70, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 71.0 in stage 0.0 (TID 71, ip-172-23-75-58.ec2.internal, executor 1, partition 71, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 72.0 in stage 0.0 (TID 72, ip-172-23-70-80.ec2.internal, executor 2, partition 72, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 73.0 in stage 0.0 (TID 73, ip-172-23-75-58.ec2.internal, executor 1, partition 73, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 74.0 in stage 0.0 (TID 74, ip-172-23-70-80.ec2.internal, executor 2, partition 74, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 75.0 in stage 0.0 (TID 75, ip-172-23-75-58.ec2.internal, executor 1, partition 75, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 76.0 in stage 0.0 (TID 76, ip-172-23-70-80.ec2.internal, executor 2, partition 76, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 77.0 in stage 0.0 (TID 77, ip-172-23-75-58.ec2.internal, executor 1, partition 77, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 78.0 in stage 0.0 (TID 78, ip-172-23-70-80.ec2.internal, executor 2, partition 78, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 79.0 in stage 0.0 (TID 79, ip-172-23-75-58.ec2.internal, executor 1, partition 79, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 80.0 in stage 0.0 (TID 80, ip-172-23-70-80.ec2.internal, executor 2, partition 80, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 81.0 in stage 0.0 (TID 81, ip-172-23-75-58.ec2.internal, executor 1, partition 81, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 82.0 in stage 0.0 (TID 82, ip-172-23-70-80.ec2.internal, executor 2, partition 82, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 83.0 in stage 0.0 (TID 83, ip-172-23-75-58.ec2.internal, executor 1, partition 83, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 84.0 in stage 0.0 (TID 84, ip-172-23-70-80.ec2.internal, executor 2, partition 84, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 85.0 in stage 0.0 (TID 85, ip-172-23-75-58.ec2.internal, executor 1, partition 85, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 86.0 in stage 0.0 (TID 86, ip-172-23-70-80.ec2.internal, executor 2, partition 86, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 87.0 in stage 0.0 (TID 87, ip-172-23-75-58.ec2.internal, executor 1, partition 87, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 88.0 in stage 0.0 (TID 88, ip-172-23-70-80.ec2.internal, executor 2, partition 88, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 89.0 in stage 0.0 (TID 89, ip-172-23-75-58.ec2.internal, executor 1, partition 89, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 90.0 in stage 0.0 (TID 90, ip-172-23-70-80.ec2.internal, executor 2, partition 90, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 91.0 in stage 0.0 (TID 91, ip-172-23-75-58.ec2.internal, executor 1, partition 91, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 92.0 in stage 0.0 (TID 92, ip-172-23-70-80.ec2.internal, executor 2, partition 92, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 93.0 in stage 0.0 (TID 93, ip-172-23-75-58.ec2.internal, executor 1, partition 93, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 94.0 in stage 0.0 (TID 94, ip-172-23-70-80.ec2.internal, executor 2, partition 94, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:01 TaskSetManager: INFO: Starting task 95.0 in stage 0.0 (TID 95, ip-172-23-75-58.ec2.internal, executor 1, partition 95, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:02 BlockManagerInfo: INFO: Added broadcast_2_piece0 in memory on ip-172-23-70-80.ec2.internal:37501 (size: 13.2 KB, free: 181.7 GB) 2022-04-01 03:25:02 BlockManagerInfo: INFO: Added broadcast_2_piece0 in memory on ip-172-23-75-58.ec2.internal:40133 (size: 13.2 KB, free: 181.7 GB) 2022-04-01 03:25:02 BlockManagerInfo: INFO: Added broadcast_0_piece0 in memory on ip-172-23-70-80.ec2.internal:37501 (size: 29.9 KB, free: 181.7 GB) 2022-04-01 03:25:02 BlockManagerInfo: INFO: Added broadcast_0_piece0 in memory on ip-172-23-75-58.ec2.internal:40133 (size: 29.9 KB, free: 181.7 GB) 2022-04-01 03:25:02 ExecutorAllocationManager: INFO: Requesting 1 new executor because tasks are backlogged (new desired total will be 5) 2022-04-01 03:25:03 ExecutorAllocationManager: INFO: Requesting 2 new executors because tasks are backlogged (new desired total will be 7) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 96.0 in stage 0.0 (TID 96, ip-172-23-70-80.ec2.internal, executor 2, partition 96, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 97.0 in stage 0.0 (TID 97, ip-172-23-70-80.ec2.internal, executor 2, partition 97, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 30.0 in stage 0.0 (TID 30) in 2008 ms on ip-172-23-70-80.ec2.internal (executor 2) (1/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 12.0 in stage 0.0 (TID 12) in 2038 ms on ip-172-23-70-80.ec2.internal (executor 2) (2/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 98.0 in stage 0.0 (TID 98, ip-172-23-70-80.ec2.internal, executor 2, partition 98, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 99.0 in stage 0.0 (TID 99, ip-172-23-70-80.ec2.internal, executor 2, partition 99, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 100.0 in stage 0.0 (TID 100, ip-172-23-70-80.ec2.internal, executor 2, partition 100, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 101.0 in stage 0.0 (TID 101, ip-172-23-70-80.ec2.internal, executor 2, partition 101, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 102.0 in stage 0.0 (TID 102, ip-172-23-70-80.ec2.internal, executor 2, partition 102, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 20.0 in stage 0.0 (TID 20) in 2040 ms on ip-172-23-70-80.ec2.internal (executor 2) (3/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 2.0 in stage 0.0 (TID 2) in 2050 ms on ip-172-23-70-80.ec2.internal (executor 2) (4/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 24.0 in stage 0.0 (TID 24) in 2040 ms on ip-172-23-70-80.ec2.internal (executor 2) (5/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 103.0 in stage 0.0 (TID 103, ip-172-23-70-80.ec2.internal, executor 2, partition 103, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 104.0 in stage 0.0 (TID 104, ip-172-23-70-80.ec2.internal, executor 2, partition 104, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 105.0 in stage 0.0 (TID 105, ip-172-23-70-80.ec2.internal, executor 2, partition 105, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 106.0 in stage 0.0 (TID 106, ip-172-23-70-80.ec2.internal, executor 2, partition 106, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 107.0 in stage 0.0 (TID 107, ip-172-23-70-80.ec2.internal, executor 2, partition 107, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 108.0 in stage 0.0 (TID 108, ip-172-23-70-80.ec2.internal, executor 2, partition 108, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 109.0 in stage 0.0 (TID 109, ip-172-23-70-80.ec2.internal, executor 2, partition 109, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 110.0 in stage 0.0 (TID 110, ip-172-23-70-80.ec2.internal, executor 2, partition 110, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 74.0 in stage 0.0 (TID 74) in 2016 ms on ip-172-23-70-80.ec2.internal (executor 2) (6/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 68.0 in stage 0.0 (TID 68) in 2023 ms on ip-172-23-70-80.ec2.internal (executor 2) (7/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 94.0 in stage 0.0 (TID 94) in 1999 ms on ip-172-23-70-80.ec2.internal (executor 2) (8/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 26.0 in stage 0.0 (TID 26) in 2054 ms on ip-172-23-70-80.ec2.internal (executor 2) (9/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 80.0 in stage 0.0 (TID 80) in 2014 ms on ip-172-23-70-80.ec2.internal (executor 2) (10/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 76.0 in stage 0.0 (TID 76) in 2016 ms on ip-172-23-70-80.ec2.internal (executor 2) (11/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 66.0 in stage 0.0 (TID 66) in 2024 ms on ip-172-23-70-80.ec2.internal (executor 2) (12/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 84.0 in stage 0.0 (TID 84) in 2013 ms on ip-172-23-70-80.ec2.internal (executor 2) (13/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 34.0 in stage 0.0 (TID 34) in 2051 ms on ip-172-23-70-80.ec2.internal (executor 2) (14/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 111.0 in stage 0.0 (TID 111, ip-172-23-70-80.ec2.internal, executor 2, partition 111, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 112.0 in stage 0.0 (TID 112, ip-172-23-70-80.ec2.internal, executor 2, partition 112, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 113.0 in stage 0.0 (TID 113, ip-172-23-70-80.ec2.internal, executor 2, partition 113, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 114.0 in stage 0.0 (TID 114, ip-172-23-70-80.ec2.internal, executor 2, partition 114, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 64.0 in stage 0.0 (TID 64) in 2031 ms on ip-172-23-70-80.ec2.internal (executor 2) (15/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 115.0 in stage 0.0 (TID 115, ip-172-23-70-80.ec2.internal, executor 2, partition 115, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 18.0 in stage 0.0 (TID 18) in 2064 ms on ip-172-23-70-80.ec2.internal (executor 2) (16/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 82.0 in stage 0.0 (TID 82) in 2021 ms on ip-172-23-70-80.ec2.internal (executor 2) (17/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 54.0 in stage 0.0 (TID 54) in 2039 ms on ip-172-23-70-80.ec2.internal (executor 2) (18/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 16.0 in stage 0.0 (TID 16) in 2067 ms on ip-172-23-70-80.ec2.internal (executor 2) (19/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 22.0 in stage 0.0 (TID 22) in 2066 ms on ip-172-23-70-80.ec2.internal (executor 2) (20/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 36.0 in stage 0.0 (TID 36) in 2067 ms on ip-172-23-70-80.ec2.internal (executor 2) (21/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 116.0 in stage 0.0 (TID 116, ip-172-23-70-80.ec2.internal, executor 2, partition 116, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 117.0 in stage 0.0 (TID 117, ip-172-23-70-80.ec2.internal, executor 2, partition 117, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 8.0 in stage 0.0 (TID 8) in 2085 ms on ip-172-23-70-80.ec2.internal (executor 2) (22/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 118.0 in stage 0.0 (TID 118, ip-172-23-70-80.ec2.internal, executor 2, partition 118, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 92.0 in stage 0.0 (TID 92) in 2023 ms on ip-172-23-70-80.ec2.internal (executor 2) (23/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 119.0 in stage 0.0 (TID 119, ip-172-23-70-80.ec2.internal, executor 2, partition 119, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 120.0 in stage 0.0 (TID 120, ip-172-23-70-80.ec2.internal, executor 2, partition 120, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 58.0 in stage 0.0 (TID 58) in 2054 ms on ip-172-23-70-80.ec2.internal (executor 2) (24/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 72.0 in stage 0.0 (TID 72) in 2047 ms on ip-172-23-70-80.ec2.internal (executor 2) (25/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 121.0 in stage 0.0 (TID 121, ip-172-23-70-80.ec2.internal, executor 2, partition 121, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 50.0 in stage 0.0 (TID 50) in 2066 ms on ip-172-23-70-80.ec2.internal (executor 2) (26/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 122.0 in stage 0.0 (TID 122, ip-172-23-70-80.ec2.internal, executor 2, partition 122, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 123.0 in stage 0.0 (TID 123, ip-172-23-70-80.ec2.internal, executor 2, partition 123, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 124.0 in stage 0.0 (TID 124, ip-172-23-70-80.ec2.internal, executor 2, partition 124, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 125.0 in stage 0.0 (TID 125, ip-172-23-70-80.ec2.internal, executor 2, partition 125, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 126.0 in stage 0.0 (TID 126, ip-172-23-70-80.ec2.internal, executor 2, partition 126, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 127.0 in stage 0.0 (TID 127, ip-172-23-70-80.ec2.internal, executor 2, partition 127, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 60.0 in stage 0.0 (TID 60) in 2064 ms on ip-172-23-70-80.ec2.internal (executor 2) (27/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 90.0 in stage 0.0 (TID 90) in 2039 ms on ip-172-23-70-80.ec2.internal (executor 2) (28/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 70.0 in stage 0.0 (TID 70) in 2061 ms on ip-172-23-70-80.ec2.internal (executor 2) (29/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 4.0 in stage 0.0 (TID 4) in 2104 ms on ip-172-23-70-80.ec2.internal (executor 2) (30/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 10.0 in stage 0.0 (TID 10) in 2103 ms on ip-172-23-70-80.ec2.internal (executor 2) (31/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 40.0 in stage 0.0 (TID 40) in 2087 ms on ip-172-23-70-80.ec2.internal (executor 2) (32/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 62.0 in stage 0.0 (TID 62) in 2065 ms on ip-172-23-70-80.ec2.internal (executor 2) (33/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 128.0 in stage 0.0 (TID 128, ip-172-23-70-80.ec2.internal, executor 2, partition 128, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 14.0 in stage 0.0 (TID 14) in 2102 ms on ip-172-23-70-80.ec2.internal (executor 2) (34/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 129.0 in stage 0.0 (TID 129, ip-172-23-70-80.ec2.internal, executor 2, partition 129, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 44.0 in stage 0.0 (TID 44) in 2084 ms on ip-172-23-70-80.ec2.internal (executor 2) (35/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 130.0 in stage 0.0 (TID 130, ip-172-23-70-80.ec2.internal, executor 2, partition 130, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 42.0 in stage 0.0 (TID 42) in 2086 ms on ip-172-23-70-80.ec2.internal (executor 2) (36/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 131.0 in stage 0.0 (TID 131, ip-172-23-70-80.ec2.internal, executor 2, partition 131, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 86.0 in stage 0.0 (TID 86) in 2056 ms on ip-172-23-70-80.ec2.internal (executor 2) (37/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 132.0 in stage 0.0 (TID 132, ip-172-23-70-80.ec2.internal, executor 2, partition 132, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 78.0 in stage 0.0 (TID 78) in 2062 ms on ip-172-23-70-80.ec2.internal (executor 2) (38/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 133.0 in stage 0.0 (TID 133, ip-172-23-70-80.ec2.internal, executor 2, partition 133, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 38.0 in stage 0.0 (TID 38) in 2097 ms on ip-172-23-70-80.ec2.internal (executor 2) (39/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 134.0 in stage 0.0 (TID 134, ip-172-23-70-80.ec2.internal, executor 2, partition 134, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 46.0 in stage 0.0 (TID 46) in 2091 ms on ip-172-23-70-80.ec2.internal (executor 2) (40/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 135.0 in stage 0.0 (TID 135, ip-172-23-70-80.ec2.internal, executor 2, partition 135, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 52.0 in stage 0.0 (TID 52) in 2089 ms on ip-172-23-70-80.ec2.internal (executor 2) (41/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 136.0 in stage 0.0 (TID 136, ip-172-23-70-80.ec2.internal, executor 2, partition 136, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 88.0 in stage 0.0 (TID 88) in 2063 ms on ip-172-23-70-80.ec2.internal (executor 2) (42/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 137.0 in stage 0.0 (TID 137, ip-172-23-70-80.ec2.internal, executor 2, partition 137, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 56.0 in stage 0.0 (TID 56) in 2086 ms on ip-172-23-70-80.ec2.internal (executor 2) (43/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 138.0 in stage 0.0 (TID 138, ip-172-23-70-80.ec2.internal, executor 2, partition 138, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 139.0 in stage 0.0 (TID 139, ip-172-23-70-80.ec2.internal, executor 2, partition 139, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 6.0 in stage 0.0 (TID 6) in 2122 ms on ip-172-23-70-80.ec2.internal (executor 2) (44/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 28.0 in stage 0.0 (TID 28) in 2111 ms on ip-172-23-70-80.ec2.internal (executor 2) (45/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 140.0 in stage 0.0 (TID 140, ip-172-23-70-80.ec2.internal, executor 2, partition 140, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 32.0 in stage 0.0 (TID 32) in 2110 ms on ip-172-23-70-80.ec2.internal (executor 2) (46/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 141.0 in stage 0.0 (TID 141, ip-172-23-70-80.ec2.internal, executor 2, partition 141, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 142.0 in stage 0.0 (TID 142, ip-172-23-70-80.ec2.internal, executor 2, partition 142, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 143.0 in stage 0.0 (TID 143, ip-172-23-70-80.ec2.internal, executor 2, partition 143, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 97.0 in stage 0.0 (TID 97) in 115 ms on ip-172-23-70-80.ec2.internal (executor 2) (47/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 96.0 in stage 0.0 (TID 96) in 117 ms on ip-172-23-70-80.ec2.internal (executor 2) (48/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 144.0 in stage 0.0 (TID 144, ip-172-23-70-80.ec2.internal, executor 2, partition 144, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 100.0 in stage 0.0 (TID 100) in 82 ms on ip-172-23-70-80.ec2.internal (executor 2) (49/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 101.0 in stage 0.0 (TID 101) in 99 ms on ip-172-23-70-80.ec2.internal (executor 2) (50/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 145.0 in stage 0.0 (TID 145, ip-172-23-70-80.ec2.internal, executor 2, partition 145, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 146.0 in stage 0.0 (TID 146, ip-172-23-75-58.ec2.internal, executor 1, partition 146, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 147.0 in stage 0.0 (TID 147, ip-172-23-75-58.ec2.internal, executor 1, partition 147, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 148.0 in stage 0.0 (TID 148, ip-172-23-75-58.ec2.internal, executor 1, partition 148, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 149.0 in stage 0.0 (TID 149, ip-172-23-75-58.ec2.internal, executor 1, partition 149, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 63.0 in stage 0.0 (TID 63) in 2110 ms on ip-172-23-75-58.ec2.internal (executor 1) (51/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 61.0 in stage 0.0 (TID 61) in 2111 ms on ip-172-23-75-58.ec2.internal (executor 1) (52/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 150.0 in stage 0.0 (TID 150, ip-172-23-75-58.ec2.internal, executor 1, partition 150, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 151.0 in stage 0.0 (TID 151, ip-172-23-75-58.ec2.internal, executor 1, partition 151, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 152.0 in stage 0.0 (TID 152, ip-172-23-75-58.ec2.internal, executor 1, partition 152, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 9.0 in stage 0.0 (TID 9) in 2163 ms on ip-172-23-75-58.ec2.internal (executor 1) (53/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 13.0 in stage 0.0 (TID 13) in 2163 ms on ip-172-23-75-58.ec2.internal (executor 1) (54/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 57.0 in stage 0.0 (TID 57) in 2128 ms on ip-172-23-75-58.ec2.internal (executor 1) (55/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 23.0 in stage 0.0 (TID 23) in 2156 ms on ip-172-23-75-58.ec2.internal (executor 1) (56/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 35.0 in stage 0.0 (TID 35) in 2150 ms on ip-172-23-75-58.ec2.internal (executor 1) (57/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 3.0 in stage 0.0 (TID 3) in 2168 ms on ip-172-23-75-58.ec2.internal (executor 1) (58/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 153.0 in stage 0.0 (TID 153, ip-172-23-75-58.ec2.internal, executor 1, partition 153, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 79.0 in stage 0.0 (TID 79) in 2119 ms on ip-172-23-75-58.ec2.internal (executor 1) (59/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 154.0 in stage 0.0 (TID 154, ip-172-23-75-58.ec2.internal, executor 1, partition 154, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 73.0 in stage 0.0 (TID 73) in 2128 ms on ip-172-23-75-58.ec2.internal (executor 1) (60/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 155.0 in stage 0.0 (TID 155, ip-172-23-75-58.ec2.internal, executor 1, partition 155, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 43.0 in stage 0.0 (TID 43) in 2151 ms on ip-172-23-75-58.ec2.internal (executor 1) (61/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 156.0 in stage 0.0 (TID 156, ip-172-23-75-58.ec2.internal, executor 1, partition 156, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 99.0 in stage 0.0 (TID 99) in 130 ms on ip-172-23-70-80.ec2.internal (executor 2) (62/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 157.0 in stage 0.0 (TID 157, ip-172-23-70-80.ec2.internal, executor 2, partition 157, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 98.0 in stage 0.0 (TID 98) in 136 ms on ip-172-23-70-80.ec2.internal (executor 2) (63/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 158.0 in stage 0.0 (TID 158, ip-172-23-70-80.ec2.internal, executor 2, partition 158, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 41.0 in stage 0.0 (TID 41) in 2162 ms on ip-172-23-75-58.ec2.internal (executor 1) (64/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 159.0 in stage 0.0 (TID 159, ip-172-23-75-58.ec2.internal, executor 1, partition 159, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 25.0 in stage 0.0 (TID 25) in 2171 ms on ip-172-23-75-58.ec2.internal (executor 1) (65/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 160.0 in stage 0.0 (TID 160, ip-172-23-75-58.ec2.internal, executor 1, partition 160, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 45.0 in stage 0.0 (TID 45) in 2159 ms on ip-172-23-75-58.ec2.internal (executor 1) (66/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 161.0 in stage 0.0 (TID 161, ip-172-23-75-58.ec2.internal, executor 1, partition 161, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 162.0 in stage 0.0 (TID 162, ip-172-23-75-58.ec2.internal, executor 1, partition 162, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 37.0 in stage 0.0 (TID 37) in 2169 ms on ip-172-23-75-58.ec2.internal (executor 1) (67/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 39.0 in stage 0.0 (TID 39) in 2170 ms on ip-172-23-75-58.ec2.internal (executor 1) (68/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 163.0 in stage 0.0 (TID 163, ip-172-23-75-58.ec2.internal, executor 1, partition 163, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 83.0 in stage 0.0 (TID 83) in 2137 ms on ip-172-23-75-58.ec2.internal (executor 1) (69/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 164.0 in stage 0.0 (TID 164, ip-172-23-75-58.ec2.internal, executor 1, partition 164, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 27.0 in stage 0.0 (TID 27) in 2178 ms on ip-172-23-75-58.ec2.internal (executor 1) (70/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 165.0 in stage 0.0 (TID 165, ip-172-23-75-58.ec2.internal, executor 1, partition 165, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 19.0 in stage 0.0 (TID 19) in 2183 ms on ip-172-23-75-58.ec2.internal (executor 1) (71/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 166.0 in stage 0.0 (TID 166, ip-172-23-75-58.ec2.internal, executor 1, partition 166, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 89.0 in stage 0.0 (TID 89) in 2129 ms on ip-172-23-75-58.ec2.internal (executor 1) (72/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 167.0 in stage 0.0 (TID 167, ip-172-23-75-58.ec2.internal, executor 1, partition 167, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 15.0 in stage 0.0 (TID 15) in 2189 ms on ip-172-23-75-58.ec2.internal (executor 1) (73/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 168.0 in stage 0.0 (TID 168, ip-172-23-75-58.ec2.internal, executor 1, partition 168, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 BlockManagerInfo: INFO: Added broadcast_1_piece0 in memory on ip-172-23-70-80.ec2.internal:37501 (size: 123.7 KB, free: 181.7 GB) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 55.0 in stage 0.0 (TID 55) in 2165 ms on ip-172-23-75-58.ec2.internal (executor 1) (74/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 169.0 in stage 0.0 (TID 169, ip-172-23-75-58.ec2.internal, executor 1, partition 169, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 49.0 in stage 0.0 (TID 49) in 2174 ms on ip-172-23-75-58.ec2.internal (executor 1) (75/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 170.0 in stage 0.0 (TID 170, ip-172-23-75-58.ec2.internal, executor 1, partition 170, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 11.0 in stage 0.0 (TID 11) in 2201 ms on ip-172-23-75-58.ec2.internal (executor 1) (76/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 171.0 in stage 0.0 (TID 171, ip-172-23-75-58.ec2.internal, executor 1, partition 171, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 17.0 in stage 0.0 (TID 17) in 2197 ms on ip-172-23-75-58.ec2.internal (executor 1) (77/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 172.0 in stage 0.0 (TID 172, ip-172-23-75-58.ec2.internal, executor 1, partition 172, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 71.0 in stage 0.0 (TID 71) in 2163 ms on ip-172-23-75-58.ec2.internal (executor 1) (78/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 173.0 in stage 0.0 (TID 173, ip-172-23-75-58.ec2.internal, executor 1, partition 173, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 5.0 in stage 0.0 (TID 5) in 2206 ms on ip-172-23-75-58.ec2.internal (executor 1) (79/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 174.0 in stage 0.0 (TID 174, ip-172-23-75-58.ec2.internal, executor 1, partition 174, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 53.0 in stage 0.0 (TID 53) in 2176 ms on ip-172-23-75-58.ec2.internal (executor 1) (80/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 175.0 in stage 0.0 (TID 175, ip-172-23-75-58.ec2.internal, executor 1, partition 175, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 87.0 in stage 0.0 (TID 87) in 2155 ms on ip-172-23-75-58.ec2.internal (executor 1) (81/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 176.0 in stage 0.0 (TID 176, ip-172-23-75-58.ec2.internal, executor 1, partition 176, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 BlockManagerInfo: INFO: Added broadcast_1_piece0 in memory on ip-172-23-75-58.ec2.internal:40133 (size: 123.7 KB, free: 181.7 GB) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 77.0 in stage 0.0 (TID 77) in 2163 ms on ip-172-23-75-58.ec2.internal (executor 1) (82/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 177.0 in stage 0.0 (TID 177, ip-172-23-75-58.ec2.internal, executor 1, partition 177, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 1.0 in stage 0.0 (TID 1) in 2224 ms on ip-172-23-75-58.ec2.internal (executor 1) (83/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 178.0 in stage 0.0 (TID 178, ip-172-23-75-58.ec2.internal, executor 1, partition 178, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 47.0 in stage 0.0 (TID 47) in 2191 ms on ip-172-23-75-58.ec2.internal (executor 1) (84/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 179.0 in stage 0.0 (TID 179, ip-172-23-75-58.ec2.internal, executor 1, partition 179, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 51.0 in stage 0.0 (TID 51) in 2190 ms on ip-172-23-75-58.ec2.internal (executor 1) (85/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 180.0 in stage 0.0 (TID 180, ip-172-23-75-58.ec2.internal, executor 1, partition 180, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 181.0 in stage 0.0 (TID 181, ip-172-23-75-58.ec2.internal, executor 1, partition 181, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 29.0 in stage 0.0 (TID 29) in 2209 ms on ip-172-23-75-58.ec2.internal (executor 1) (86/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 67.0 in stage 0.0 (TID 67) in 2181 ms on ip-172-23-75-58.ec2.internal (executor 1) (87/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 182.0 in stage 0.0 (TID 182, ip-172-23-75-58.ec2.internal, executor 1, partition 182, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 7.0 in stage 0.0 (TID 7) in 2223 ms on ip-172-23-75-58.ec2.internal (executor 1) (88/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 183.0 in stage 0.0 (TID 183, ip-172-23-75-58.ec2.internal, executor 1, partition 183, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 69.0 in stage 0.0 (TID 69) in 2182 ms on ip-172-23-75-58.ec2.internal (executor 1) (89/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 184.0 in stage 0.0 (TID 184, ip-172-23-75-58.ec2.internal, executor 1, partition 184, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 65.0 in stage 0.0 (TID 65) in 2185 ms on ip-172-23-75-58.ec2.internal (executor 1) (90/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 185.0 in stage 0.0 (TID 185, ip-172-23-75-58.ec2.internal, executor 1, partition 185, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 21.0 in stage 0.0 (TID 21) in 2220 ms on ip-172-23-75-58.ec2.internal (executor 1) (91/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 186.0 in stage 0.0 (TID 186, ip-172-23-75-58.ec2.internal, executor 1, partition 186, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 33.0 in stage 0.0 (TID 33) in 2215 ms on ip-172-23-75-58.ec2.internal (executor 1) (92/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 187.0 in stage 0.0 (TID 187, ip-172-23-75-58.ec2.internal, executor 1, partition 187, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 93.0 in stage 0.0 (TID 93) in 2165 ms on ip-172-23-75-58.ec2.internal (executor 1) (93/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 188.0 in stage 0.0 (TID 188, ip-172-23-75-58.ec2.internal, executor 1, partition 188, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 85.0 in stage 0.0 (TID 85) in 2178 ms on ip-172-23-75-58.ec2.internal (executor 1) (94/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 189.0 in stage 0.0 (TID 189, ip-172-23-75-58.ec2.internal, executor 1, partition 189, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 95.0 in stage 0.0 (TID 95) in 2167 ms on ip-172-23-75-58.ec2.internal (executor 1) (95/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 190.0 in stage 0.0 (TID 190, ip-172-23-75-58.ec2.internal, executor 1, partition 190, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 91.0 in stage 0.0 (TID 91) in 2171 ms on ip-172-23-75-58.ec2.internal (executor 1) (96/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 191.0 in stage 0.0 (TID 191, ip-172-23-75-58.ec2.internal, executor 1, partition 191, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 59.0 in stage 0.0 (TID 59) in 2201 ms on ip-172-23-75-58.ec2.internal (executor 1) (97/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 192.0 in stage 0.0 (TID 192, ip-172-23-75-58.ec2.internal, executor 1, partition 192, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:03 TaskSetManager: INFO: Finished task 81.0 in stage 0.0 (TID 81) in 2188 ms on ip-172-23-75-58.ec2.internal (executor 1) (98/500) 2022-04-01 03:25:03 TaskSetManager: INFO: Starting task 193.0 in stage 0.0 (TID 193, ip-172-23-75-58.ec2.internal, executor 1, partition 193, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 194.0 in stage 0.0 (TID 194, ip-172-23-70-80.ec2.internal, executor 2, partition 194, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 0.0 in stage 0.0 (TID 0) in 2321 ms on ip-172-23-70-80.ec2.internal (executor 2) (99/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 195.0 in stage 0.0 (TID 195, ip-172-23-70-80.ec2.internal, executor 2, partition 195, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 141.0 in stage 0.0 (TID 141) in 185 ms on ip-172-23-70-80.ec2.internal (executor 2) (100/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 196.0 in stage 0.0 (TID 196, ip-172-23-70-80.ec2.internal, executor 2, partition 196, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 197.0 in stage 0.0 (TID 197, ip-172-23-70-80.ec2.internal, executor 2, partition 197, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 198.0 in stage 0.0 (TID 198, ip-172-23-70-80.ec2.internal, executor 2, partition 198, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 199.0 in stage 0.0 (TID 199, ip-172-23-70-80.ec2.internal, executor 2, partition 199, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 142.0 in stage 0.0 (TID 142) in 189 ms on ip-172-23-70-80.ec2.internal (executor 2) (101/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 129.0 in stage 0.0 (TID 129) in 208 ms on ip-172-23-70-80.ec2.internal (executor 2) (102/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 124.0 in stage 0.0 (TID 124) in 219 ms on ip-172-23-70-80.ec2.internal (executor 2) (103/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 128.0 in stage 0.0 (TID 128) in 211 ms on ip-172-23-70-80.ec2.internal (executor 2) (104/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 200.0 in stage 0.0 (TID 200, ip-172-23-70-80.ec2.internal, executor 2, partition 200, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 134.0 in stage 0.0 (TID 134) in 201 ms on ip-172-23-70-80.ec2.internal (executor 2) (105/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 130.0 in stage 0.0 (TID 130) in 210 ms on ip-172-23-70-80.ec2.internal (executor 2) (106/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 201.0 in stage 0.0 (TID 201, ip-172-23-70-80.ec2.internal, executor 2, partition 201, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 108.0 in stage 0.0 (TID 108) in 256 ms on ip-172-23-70-80.ec2.internal (executor 2) (107/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 202.0 in stage 0.0 (TID 202, ip-172-23-70-80.ec2.internal, executor 2, partition 202, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 203.0 in stage 0.0 (TID 203, ip-172-23-70-80.ec2.internal, executor 2, partition 203, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 127.0 in stage 0.0 (TID 127) in 226 ms on ip-172-23-70-80.ec2.internal (executor 2) (108/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 204.0 in stage 0.0 (TID 204, ip-172-23-70-80.ec2.internal, executor 2, partition 204, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 205.0 in stage 0.0 (TID 205, ip-172-23-70-80.ec2.internal, executor 2, partition 205, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 206.0 in stage 0.0 (TID 206, ip-172-23-70-80.ec2.internal, executor 2, partition 206, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 207.0 in stage 0.0 (TID 207, ip-172-23-70-80.ec2.internal, executor 2, partition 207, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 208.0 in stage 0.0 (TID 208, ip-172-23-70-80.ec2.internal, executor 2, partition 208, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 209.0 in stage 0.0 (TID 209, ip-172-23-70-80.ec2.internal, executor 2, partition 209, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 210.0 in stage 0.0 (TID 210, ip-172-23-70-80.ec2.internal, executor 2, partition 210, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 211.0 in stage 0.0 (TID 211, ip-172-23-70-80.ec2.internal, executor 2, partition 211, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 212.0 in stage 0.0 (TID 212, ip-172-23-70-80.ec2.internal, executor 2, partition 212, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 213.0 in stage 0.0 (TID 213, ip-172-23-70-80.ec2.internal, executor 2, partition 213, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 214.0 in stage 0.0 (TID 214, ip-172-23-70-80.ec2.internal, executor 2, partition 214, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 136.0 in stage 0.0 (TID 136) in 223 ms on ip-172-23-70-80.ec2.internal (executor 2) (109/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 143.0 in stage 0.0 (TID 143) in 214 ms on ip-172-23-70-80.ec2.internal (executor 2) (110/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 133.0 in stage 0.0 (TID 133) in 229 ms on ip-172-23-70-80.ec2.internal (executor 2) (111/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 116.0 in stage 0.0 (TID 116) in 258 ms on ip-172-23-70-80.ec2.internal (executor 2) (112/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 126.0 in stage 0.0 (TID 126) in 241 ms on ip-172-23-70-80.ec2.internal (executor 2) (113/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 125.0 in stage 0.0 (TID 125) in 245 ms on ip-172-23-70-80.ec2.internal (executor 2) (114/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 107.0 in stage 0.0 (TID 107) in 280 ms on ip-172-23-70-80.ec2.internal (executor 2) (115/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 140.0 in stage 0.0 (TID 140) in 219 ms on ip-172-23-70-80.ec2.internal (executor 2) (116/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 131.0 in stage 0.0 (TID 131) in 234 ms on ip-172-23-70-80.ec2.internal (executor 2) (117/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 139.0 in stage 0.0 (TID 139) in 221 ms on ip-172-23-70-80.ec2.internal (executor 2) (118/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 123.0 in stage 0.0 (TID 123) in 247 ms on ip-172-23-70-80.ec2.internal (executor 2) (119/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 215.0 in stage 0.0 (TID 215, ip-172-23-70-80.ec2.internal, executor 2, partition 215, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 216.0 in stage 0.0 (TID 216, ip-172-23-70-80.ec2.internal, executor 2, partition 216, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 217.0 in stage 0.0 (TID 217, ip-172-23-70-80.ec2.internal, executor 2, partition 217, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 218.0 in stage 0.0 (TID 218, ip-172-23-70-80.ec2.internal, executor 2, partition 218, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 219.0 in stage 0.0 (TID 219, ip-172-23-70-80.ec2.internal, executor 2, partition 219, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 220.0 in stage 0.0 (TID 220, ip-172-23-70-80.ec2.internal, executor 2, partition 220, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 221.0 in stage 0.0 (TID 221, ip-172-23-70-80.ec2.internal, executor 2, partition 221, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 222.0 in stage 0.0 (TID 222, ip-172-23-70-80.ec2.internal, executor 2, partition 222, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 223.0 in stage 0.0 (TID 223, ip-172-23-70-80.ec2.internal, executor 2, partition 223, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 224.0 in stage 0.0 (TID 224, ip-172-23-70-80.ec2.internal, executor 2, partition 224, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 225.0 in stage 0.0 (TID 225, ip-172-23-70-80.ec2.internal, executor 2, partition 225, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 226.0 in stage 0.0 (TID 226, ip-172-23-70-80.ec2.internal, executor 2, partition 226, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 227.0 in stage 0.0 (TID 227, ip-172-23-70-80.ec2.internal, executor 2, partition 227, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 228.0 in stage 0.0 (TID 228, ip-172-23-70-80.ec2.internal, executor 2, partition 228, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 114.0 in stage 0.0 (TID 114) in 283 ms on ip-172-23-70-80.ec2.internal (executor 2) (120/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 135.0 in stage 0.0 (TID 135) in 237 ms on ip-172-23-70-80.ec2.internal (executor 2) (121/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 132.0 in stage 0.0 (TID 132) in 243 ms on ip-172-23-70-80.ec2.internal (executor 2) (122/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 145.0 in stage 0.0 (TID 145) in 208 ms on ip-172-23-70-80.ec2.internal (executor 2) (123/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 122.0 in stage 0.0 (TID 122) in 260 ms on ip-172-23-70-80.ec2.internal (executor 2) (124/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 137.0 in stage 0.0 (TID 137) in 236 ms on ip-172-23-70-80.ec2.internal (executor 2) (125/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 117.0 in stage 0.0 (TID 117) in 271 ms on ip-172-23-70-80.ec2.internal (executor 2) (126/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 103.0 in stage 0.0 (TID 103) in 300 ms on ip-172-23-70-80.ec2.internal (executor 2) (127/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 144.0 in stage 0.0 (TID 144) in 228 ms on ip-172-23-70-80.ec2.internal (executor 2) (128/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 120.0 in stage 0.0 (TID 120) in 265 ms on ip-172-23-70-80.ec2.internal (executor 2) (129/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 115.0 in stage 0.0 (TID 115) in 284 ms on ip-172-23-70-80.ec2.internal (executor 2) (130/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 118.0 in stage 0.0 (TID 118) in 268 ms on ip-172-23-70-80.ec2.internal (executor 2) (131/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 106.0 in stage 0.0 (TID 106) in 298 ms on ip-172-23-70-80.ec2.internal (executor 2) (132/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 112.0 in stage 0.0 (TID 112) in 290 ms on ip-172-23-70-80.ec2.internal (executor 2) (133/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 229.0 in stage 0.0 (TID 229, ip-172-23-70-80.ec2.internal, executor 2, partition 229, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 157.0 in stage 0.0 (TID 157) in 194 ms on ip-172-23-70-80.ec2.internal (executor 2) (134/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 230.0 in stage 0.0 (TID 230, ip-172-23-70-80.ec2.internal, executor 2, partition 230, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 158.0 in stage 0.0 (TID 158) in 197 ms on ip-172-23-70-80.ec2.internal (executor 2) (135/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 231.0 in stage 0.0 (TID 231, ip-172-23-70-80.ec2.internal, executor 2, partition 231, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 104.0 in stage 0.0 (TID 104) in 327 ms on ip-172-23-70-80.ec2.internal (executor 2) (136/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 232.0 in stage 0.0 (TID 232, ip-172-23-70-80.ec2.internal, executor 2, partition 232, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 110.0 in stage 0.0 (TID 110) in 320 ms on ip-172-23-70-80.ec2.internal (executor 2) (137/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 233.0 in stage 0.0 (TID 233, ip-172-23-70-80.ec2.internal, executor 2, partition 233, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 113.0 in stage 0.0 (TID 113) in 314 ms on ip-172-23-70-80.ec2.internal (executor 2) (138/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 234.0 in stage 0.0 (TID 234, ip-172-23-70-80.ec2.internal, executor 2, partition 234, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 105.0 in stage 0.0 (TID 105) in 338 ms on ip-172-23-70-80.ec2.internal (executor 2) (139/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 235.0 in stage 0.0 (TID 235, ip-172-23-70-80.ec2.internal, executor 2, partition 235, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 102.0 in stage 0.0 (TID 102) in 347 ms on ip-172-23-70-80.ec2.internal (executor 2) (140/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 236.0 in stage 0.0 (TID 236, ip-172-23-70-80.ec2.internal, executor 2, partition 236, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 138.0 in stage 0.0 (TID 138) in 279 ms on ip-172-23-70-80.ec2.internal (executor 2) (141/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 237.0 in stage 0.0 (TID 237, ip-172-23-70-80.ec2.internal, executor 2, partition 237, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 238.0 in stage 0.0 (TID 238, ip-172-23-70-80.ec2.internal, executor 2, partition 238, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 194.0 in stage 0.0 (TID 194) in 108 ms on ip-172-23-70-80.ec2.internal (executor 2) (142/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 239.0 in stage 0.0 (TID 239, ip-172-23-70-80.ec2.internal, executor 2, partition 239, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 31.0 in stage 0.0 (TID 31) in 2404 ms on ip-172-23-75-58.ec2.internal (executor 1) (143/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 240.0 in stage 0.0 (TID 240, ip-172-23-75-58.ec2.internal, executor 1, partition 240, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 109.0 in stage 0.0 (TID 109) in 357 ms on ip-172-23-70-80.ec2.internal (executor 2) (144/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 241.0 in stage 0.0 (TID 241, ip-172-23-70-80.ec2.internal, executor 2, partition 241, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 195.0 in stage 0.0 (TID 195) in 115 ms on ip-172-23-70-80.ec2.internal (executor 2) (145/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 242.0 in stage 0.0 (TID 242, ip-172-23-70-80.ec2.internal, executor 2, partition 242, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 119.0 in stage 0.0 (TID 119) in 334 ms on ip-172-23-70-80.ec2.internal (executor 2) (146/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 243.0 in stage 0.0 (TID 243, ip-172-23-70-80.ec2.internal, executor 2, partition 243, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 111.0 in stage 0.0 (TID 111) in 359 ms on ip-172-23-70-80.ec2.internal (executor 2) (147/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 244.0 in stage 0.0 (TID 244, ip-172-23-70-80.ec2.internal, executor 2, partition 244, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 200.0 in stage 0.0 (TID 200) in 114 ms on ip-172-23-70-80.ec2.internal (executor 2) (148/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 245.0 in stage 0.0 (TID 245, ip-172-23-70-80.ec2.internal, executor 2, partition 245, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 246.0 in stage 0.0 (TID 246, ip-172-23-70-80.ec2.internal, executor 2, partition 246, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 247.0 in stage 0.0 (TID 247, ip-172-23-70-80.ec2.internal, executor 2, partition 247, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 248.0 in stage 0.0 (TID 248, ip-172-23-70-80.ec2.internal, executor 2, partition 248, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 249.0 in stage 0.0 (TID 249, ip-172-23-70-80.ec2.internal, executor 2, partition 249, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 250.0 in stage 0.0 (TID 250, ip-172-23-70-80.ec2.internal, executor 2, partition 250, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 251.0 in stage 0.0 (TID 251, ip-172-23-75-58.ec2.internal, executor 1, partition 251, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 252.0 in stage 0.0 (TID 252, ip-172-23-75-58.ec2.internal, executor 1, partition 252, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 253.0 in stage 0.0 (TID 253, ip-172-23-75-58.ec2.internal, executor 1, partition 253, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 254.0 in stage 0.0 (TID 254, ip-172-23-75-58.ec2.internal, executor 1, partition 254, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 255.0 in stage 0.0 (TID 255, ip-172-23-75-58.ec2.internal, executor 1, partition 255, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 256.0 in stage 0.0 (TID 256, ip-172-23-75-58.ec2.internal, executor 1, partition 256, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 257.0 in stage 0.0 (TID 257, ip-172-23-75-58.ec2.internal, executor 1, partition 257, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 258.0 in stage 0.0 (TID 258, ip-172-23-75-58.ec2.internal, executor 1, partition 258, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 259.0 in stage 0.0 (TID 259, ip-172-23-75-58.ec2.internal, executor 1, partition 259, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 260.0 in stage 0.0 (TID 260, ip-172-23-75-58.ec2.internal, executor 1, partition 260, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 261.0 in stage 0.0 (TID 261, ip-172-23-75-58.ec2.internal, executor 1, partition 261, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 262.0 in stage 0.0 (TID 262, ip-172-23-75-58.ec2.internal, executor 1, partition 262, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 121.0 in stage 0.0 (TID 121) in 380 ms on ip-172-23-70-80.ec2.internal (executor 2) (149/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 198.0 in stage 0.0 (TID 198) in 160 ms on ip-172-23-70-80.ec2.internal (executor 2) (150/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 199.0 in stage 0.0 (TID 199) in 160 ms on ip-172-23-70-80.ec2.internal (executor 2) (151/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 197.0 in stage 0.0 (TID 197) in 161 ms on ip-172-23-70-80.ec2.internal (executor 2) (152/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 181.0 in stage 0.0 (TID 181) in 253 ms on ip-172-23-75-58.ec2.internal (executor 1) (153/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 182.0 in stage 0.0 (TID 182) in 252 ms on ip-172-23-75-58.ec2.internal (executor 1) (154/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 178.0 in stage 0.0 (TID 178) in 261 ms on ip-172-23-75-58.ec2.internal (executor 1) (155/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 175.0 in stage 0.0 (TID 175) in 266 ms on ip-172-23-75-58.ec2.internal (executor 1) (156/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 171.0 in stage 0.0 (TID 171) in 272 ms on ip-172-23-75-58.ec2.internal (executor 1) (157/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 174.0 in stage 0.0 (TID 174) in 268 ms on ip-172-23-75-58.ec2.internal (executor 1) (158/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 189.0 in stage 0.0 (TID 189) in 244 ms on ip-172-23-75-58.ec2.internal (executor 1) (159/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 161.0 in stage 0.0 (TID 161) in 293 ms on ip-172-23-75-58.ec2.internal (executor 1) (160/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 183.0 in stage 0.0 (TID 183) in 252 ms on ip-172-23-75-58.ec2.internal (executor 1) (161/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 152.0 in stage 0.0 (TID 152) in 314 ms on ip-172-23-75-58.ec2.internal (executor 1) (162/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 191.0 in stage 0.0 (TID 191) in 241 ms on ip-172-23-75-58.ec2.internal (executor 1) (163/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 170.0 in stage 0.0 (TID 170) in 276 ms on ip-172-23-75-58.ec2.internal (executor 1) (164/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 48.0 in stage 0.0 (TID 48) in 2451 ms on ip-172-23-70-80.ec2.internal (executor 2) (165/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 201.0 in stage 0.0 (TID 201) in 159 ms on ip-172-23-70-80.ec2.internal (executor 2) (166/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 196.0 in stage 0.0 (TID 196) in 165 ms on ip-172-23-70-80.ec2.internal (executor 2) (167/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 263.0 in stage 0.0 (TID 263, ip-172-23-75-58.ec2.internal, executor 1, partition 263, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 264.0 in stage 0.0 (TID 264, ip-172-23-75-58.ec2.internal, executor 1, partition 264, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 265.0 in stage 0.0 (TID 265, ip-172-23-75-58.ec2.internal, executor 1, partition 265, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 266.0 in stage 0.0 (TID 266, ip-172-23-75-58.ec2.internal, executor 1, partition 266, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 267.0 in stage 0.0 (TID 267, ip-172-23-75-58.ec2.internal, executor 1, partition 267, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 268.0 in stage 0.0 (TID 268, ip-172-23-75-58.ec2.internal, executor 1, partition 268, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 269.0 in stage 0.0 (TID 269, ip-172-23-75-58.ec2.internal, executor 1, partition 269, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 270.0 in stage 0.0 (TID 270, ip-172-23-75-58.ec2.internal, executor 1, partition 270, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 271.0 in stage 0.0 (TID 271, ip-172-23-75-58.ec2.internal, executor 1, partition 271, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 272.0 in stage 0.0 (TID 272, ip-172-23-75-58.ec2.internal, executor 1, partition 272, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 273.0 in stage 0.0 (TID 273, ip-172-23-75-58.ec2.internal, executor 1, partition 273, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 274.0 in stage 0.0 (TID 274, ip-172-23-75-58.ec2.internal, executor 1, partition 274, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 275.0 in stage 0.0 (TID 275, ip-172-23-75-58.ec2.internal, executor 1, partition 275, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 172.0 in stage 0.0 (TID 172) in 310 ms on ip-172-23-75-58.ec2.internal (executor 1) (168/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 163.0 in stage 0.0 (TID 163) in 325 ms on ip-172-23-75-58.ec2.internal (executor 1) (169/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 179.0 in stage 0.0 (TID 179) in 298 ms on ip-172-23-75-58.ec2.internal (executor 1) (170/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 159.0 in stage 0.0 (TID 159) in 335 ms on ip-172-23-75-58.ec2.internal (executor 1) (171/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 149.0 in stage 0.0 (TID 149) in 366 ms on ip-172-23-75-58.ec2.internal (executor 1) (172/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 188.0 in stage 0.0 (TID 188) in 284 ms on ip-172-23-75-58.ec2.internal (executor 1) (173/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 156.0 in stage 0.0 (TID 156) in 341 ms on ip-172-23-75-58.ec2.internal (executor 1) (174/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 162.0 in stage 0.0 (TID 162) in 331 ms on ip-172-23-75-58.ec2.internal (executor 1) (175/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 192.0 in stage 0.0 (TID 192) in 277 ms on ip-172-23-75-58.ec2.internal (executor 1) (176/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 184.0 in stage 0.0 (TID 184) in 291 ms on ip-172-23-75-58.ec2.internal (executor 1) (177/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 187.0 in stage 0.0 (TID 187) in 285 ms on ip-172-23-75-58.ec2.internal (executor 1) (178/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 168.0 in stage 0.0 (TID 168) in 322 ms on ip-172-23-75-58.ec2.internal (executor 1) (179/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 75.0 in stage 0.0 (TID 75) in 2468 ms on ip-172-23-75-58.ec2.internal (executor 1) (180/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 276.0 in stage 0.0 (TID 276, ip-172-23-75-58.ec2.internal, executor 1, partition 276, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 277.0 in stage 0.0 (TID 277, ip-172-23-75-58.ec2.internal, executor 1, partition 277, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 278.0 in stage 0.0 (TID 278, ip-172-23-75-58.ec2.internal, executor 1, partition 278, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 279.0 in stage 0.0 (TID 279, ip-172-23-75-58.ec2.internal, executor 1, partition 279, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 280.0 in stage 0.0 (TID 280, ip-172-23-75-58.ec2.internal, executor 1, partition 280, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 154.0 in stage 0.0 (TID 154) in 367 ms on ip-172-23-75-58.ec2.internal (executor 1) (181/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 155.0 in stage 0.0 (TID 155) in 365 ms on ip-172-23-75-58.ec2.internal (executor 1) (182/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 180.0 in stage 0.0 (TID 180) in 320 ms on ip-172-23-75-58.ec2.internal (executor 1) (183/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 176.0 in stage 0.0 (TID 176) in 326 ms on ip-172-23-75-58.ec2.internal (executor 1) (184/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 147.0 in stage 0.0 (TID 147) in 391 ms on ip-172-23-75-58.ec2.internal (executor 1) (185/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 150.0 in stage 0.0 (TID 150) in 379 ms on ip-172-23-75-58.ec2.internal (executor 1) (186/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 281.0 in stage 0.0 (TID 281, ip-172-23-75-58.ec2.internal, executor 1, partition 281, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 190.0 in stage 0.0 (TID 190) in 306 ms on ip-172-23-75-58.ec2.internal (executor 1) (187/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 282.0 in stage 0.0 (TID 282, ip-172-23-75-58.ec2.internal, executor 1, partition 282, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 146.0 in stage 0.0 (TID 146) in 394 ms on ip-172-23-75-58.ec2.internal (executor 1) (188/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 283.0 in stage 0.0 (TID 283, ip-172-23-75-58.ec2.internal, executor 1, partition 283, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 284.0 in stage 0.0 (TID 284, ip-172-23-70-80.ec2.internal, executor 2, partition 284, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 207.0 in stage 0.0 (TID 207) in 211 ms on ip-172-23-70-80.ec2.internal (executor 2) (189/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 212.0 in stage 0.0 (TID 212) in 209 ms on ip-172-23-70-80.ec2.internal (executor 2) (190/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 285.0 in stage 0.0 (TID 285, ip-172-23-70-80.ec2.internal, executor 2, partition 285, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 151.0 in stage 0.0 (TID 151) in 386 ms on ip-172-23-75-58.ec2.internal (executor 1) (191/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 286.0 in stage 0.0 (TID 286, ip-172-23-75-58.ec2.internal, executor 1, partition 286, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 169.0 in stage 0.0 (TID 169) in 354 ms on ip-172-23-75-58.ec2.internal (executor 1) (192/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 287.0 in stage 0.0 (TID 287, ip-172-23-75-58.ec2.internal, executor 1, partition 287, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 210.0 in stage 0.0 (TID 210) in 216 ms on ip-172-23-70-80.ec2.internal (executor 2) (193/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 288.0 in stage 0.0 (TID 288, ip-172-23-70-80.ec2.internal, executor 2, partition 288, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 185.0 in stage 0.0 (TID 185) in 326 ms on ip-172-23-75-58.ec2.internal (executor 1) (194/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 289.0 in stage 0.0 (TID 289, ip-172-23-75-58.ec2.internal, executor 1, partition 289, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 203.0 in stage 0.0 (TID 203) in 227 ms on ip-172-23-70-80.ec2.internal (executor 2) (195/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 290.0 in stage 0.0 (TID 290, ip-172-23-70-80.ec2.internal, executor 2, partition 290, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 202.0 in stage 0.0 (TID 202) in 238 ms on ip-172-23-70-80.ec2.internal (executor 2) (196/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 291.0 in stage 0.0 (TID 291, ip-172-23-70-80.ec2.internal, executor 2, partition 291, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 166.0 in stage 0.0 (TID 166) in 367 ms on ip-172-23-75-58.ec2.internal (executor 1) (197/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 292.0 in stage 0.0 (TID 292, ip-172-23-75-58.ec2.internal, executor 1, partition 292, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 173.0 in stage 0.0 (TID 173) in 353 ms on ip-172-23-75-58.ec2.internal (executor 1) (198/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 293.0 in stage 0.0 (TID 293, ip-172-23-75-58.ec2.internal, executor 1, partition 293, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 193.0 in stage 0.0 (TID 193) in 320 ms on ip-172-23-75-58.ec2.internal (executor 1) (199/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 294.0 in stage 0.0 (TID 294, ip-172-23-75-58.ec2.internal, executor 1, partition 294, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 148.0 in stage 0.0 (TID 148) in 415 ms on ip-172-23-75-58.ec2.internal (executor 1) (200/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 295.0 in stage 0.0 (TID 295, ip-172-23-75-58.ec2.internal, executor 1, partition 295, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 205.0 in stage 0.0 (TID 205) in 230 ms on ip-172-23-70-80.ec2.internal (executor 2) (201/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 296.0 in stage 0.0 (TID 296, ip-172-23-70-80.ec2.internal, executor 2, partition 296, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 214.0 in stage 0.0 (TID 214) in 226 ms on ip-172-23-70-80.ec2.internal (executor 2) (202/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 297.0 in stage 0.0 (TID 297, ip-172-23-70-80.ec2.internal, executor 2, partition 297, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 211.0 in stage 0.0 (TID 211) in 229 ms on ip-172-23-70-80.ec2.internal (executor 2) (203/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 298.0 in stage 0.0 (TID 298, ip-172-23-70-80.ec2.internal, executor 2, partition 298, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 208.0 in stage 0.0 (TID 208) in 231 ms on ip-172-23-70-80.ec2.internal (executor 2) (204/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 299.0 in stage 0.0 (TID 299, ip-172-23-70-80.ec2.internal, executor 2, partition 299, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 177.0 in stage 0.0 (TID 177) in 356 ms on ip-172-23-75-58.ec2.internal (executor 1) (205/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 300.0 in stage 0.0 (TID 300, ip-172-23-75-58.ec2.internal, executor 1, partition 300, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 216.0 in stage 0.0 (TID 216) in 225 ms on ip-172-23-70-80.ec2.internal (executor 2) (206/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 301.0 in stage 0.0 (TID 301, ip-172-23-70-80.ec2.internal, executor 2, partition 301, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 225.0 in stage 0.0 (TID 225) in 221 ms on ip-172-23-70-80.ec2.internal (executor 2) (207/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 302.0 in stage 0.0 (TID 302, ip-172-23-70-80.ec2.internal, executor 2, partition 302, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 167.0 in stage 0.0 (TID 167) in 380 ms on ip-172-23-75-58.ec2.internal (executor 1) (208/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 303.0 in stage 0.0 (TID 303, ip-172-23-75-58.ec2.internal, executor 1, partition 303, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 218.0 in stage 0.0 (TID 218) in 229 ms on ip-172-23-70-80.ec2.internal (executor 2) (209/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 304.0 in stage 0.0 (TID 304, ip-172-23-70-80.ec2.internal, executor 2, partition 304, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 222.0 in stage 0.0 (TID 222) in 228 ms on ip-172-23-70-80.ec2.internal (executor 2) (210/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 305.0 in stage 0.0 (TID 305, ip-172-23-70-80.ec2.internal, executor 2, partition 305, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 209.0 in stage 0.0 (TID 209) in 244 ms on ip-172-23-70-80.ec2.internal (executor 2) (211/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 306.0 in stage 0.0 (TID 306, ip-172-23-70-80.ec2.internal, executor 2, partition 306, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 232.0 in stage 0.0 (TID 232) in 200 ms on ip-172-23-70-80.ec2.internal (executor 2) (212/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 307.0 in stage 0.0 (TID 307, ip-172-23-70-80.ec2.internal, executor 2, partition 307, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 213.0 in stage 0.0 (TID 213) in 249 ms on ip-172-23-70-80.ec2.internal (executor 2) (213/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 308.0 in stage 0.0 (TID 308, ip-172-23-70-80.ec2.internal, executor 2, partition 308, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 165.0 in stage 0.0 (TID 165) in 400 ms on ip-172-23-75-58.ec2.internal (executor 1) (214/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 309.0 in stage 0.0 (TID 309, ip-172-23-75-58.ec2.internal, executor 1, partition 309, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 160.0 in stage 0.0 (TID 160) in 410 ms on ip-172-23-75-58.ec2.internal (executor 1) (215/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 310.0 in stage 0.0 (TID 310, ip-172-23-75-58.ec2.internal, executor 1, partition 310, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 153.0 in stage 0.0 (TID 153) in 427 ms on ip-172-23-75-58.ec2.internal (executor 1) (216/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 311.0 in stage 0.0 (TID 311, ip-172-23-75-58.ec2.internal, executor 1, partition 311, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 186.0 in stage 0.0 (TID 186) in 368 ms on ip-172-23-75-58.ec2.internal (executor 1) (217/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 312.0 in stage 0.0 (TID 312, ip-172-23-75-58.ec2.internal, executor 1, partition 312, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 164.0 in stage 0.0 (TID 164) in 410 ms on ip-172-23-75-58.ec2.internal (executor 1) (218/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 313.0 in stage 0.0 (TID 313, ip-172-23-75-58.ec2.internal, executor 1, partition 313, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 221.0 in stage 0.0 (TID 221) in 252 ms on ip-172-23-70-80.ec2.internal (executor 2) (219/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 314.0 in stage 0.0 (TID 314, ip-172-23-70-80.ec2.internal, executor 2, partition 314, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 315.0 in stage 0.0 (TID 315, ip-172-23-70-80.ec2.internal, executor 2, partition 315, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 224.0 in stage 0.0 (TID 224) in 261 ms on ip-172-23-70-80.ec2.internal (executor 2) (220/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 233.0 in stage 0.0 (TID 233) in 233 ms on ip-172-23-70-80.ec2.internal (executor 2) (221/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 316.0 in stage 0.0 (TID 316, ip-172-23-70-80.ec2.internal, executor 2, partition 316, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 231.0 in stage 0.0 (TID 231) in 243 ms on ip-172-23-70-80.ec2.internal (executor 2) (222/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 317.0 in stage 0.0 (TID 317, ip-172-23-70-80.ec2.internal, executor 2, partition 317, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 230.0 in stage 0.0 (TID 230) in 249 ms on ip-172-23-70-80.ec2.internal (executor 2) (223/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 318.0 in stage 0.0 (TID 318, ip-172-23-70-80.ec2.internal, executor 2, partition 318, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 319.0 in stage 0.0 (TID 319, ip-172-23-70-80.ec2.internal, executor 2, partition 319, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 204.0 in stage 0.0 (TID 204) in 286 ms on ip-172-23-70-80.ec2.internal (executor 2) (224/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 229.0 in stage 0.0 (TID 229) in 253 ms on ip-172-23-70-80.ec2.internal (executor 2) (225/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 320.0 in stage 0.0 (TID 320, ip-172-23-70-80.ec2.internal, executor 2, partition 320, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 220.0 in stage 0.0 (TID 220) in 272 ms on ip-172-23-70-80.ec2.internal (executor 2) (226/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 321.0 in stage 0.0 (TID 321, ip-172-23-70-80.ec2.internal, executor 2, partition 321, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 240.0 in stage 0.0 (TID 240) in 203 ms on ip-172-23-75-58.ec2.internal (executor 1) (227/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 322.0 in stage 0.0 (TID 322, ip-172-23-75-58.ec2.internal, executor 1, partition 322, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 323.0 in stage 0.0 (TID 323, ip-172-23-70-80.ec2.internal, executor 2, partition 323, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 226.0 in stage 0.0 (TID 226) in 271 ms on ip-172-23-70-80.ec2.internal (executor 2) (228/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 223.0 in stage 0.0 (TID 223) in 278 ms on ip-172-23-70-80.ec2.internal (executor 2) (229/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 324.0 in stage 0.0 (TID 324, ip-172-23-70-80.ec2.internal, executor 2, partition 324, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 215.0 in stage 0.0 (TID 215) in 283 ms on ip-172-23-70-80.ec2.internal (executor 2) (230/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 325.0 in stage 0.0 (TID 325, ip-172-23-70-80.ec2.internal, executor 2, partition 325, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 227.0 in stage 0.0 (TID 227) in 278 ms on ip-172-23-70-80.ec2.internal (executor 2) (231/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 326.0 in stage 0.0 (TID 326, ip-172-23-70-80.ec2.internal, executor 2, partition 326, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 327.0 in stage 0.0 (TID 327, ip-172-23-70-80.ec2.internal, executor 2, partition 327, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 228.0 in stage 0.0 (TID 228) in 279 ms on ip-172-23-70-80.ec2.internal (executor 2) (232/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 328.0 in stage 0.0 (TID 328, ip-172-23-70-80.ec2.internal, executor 2, partition 328, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 217.0 in stage 0.0 (TID 217) in 285 ms on ip-172-23-70-80.ec2.internal (executor 2) (233/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 219.0 in stage 0.0 (TID 219) in 285 ms on ip-172-23-70-80.ec2.internal (executor 2) (234/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 329.0 in stage 0.0 (TID 329, ip-172-23-70-80.ec2.internal, executor 2, partition 329, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 330.0 in stage 0.0 (TID 330, ip-172-23-70-80.ec2.internal, executor 2, partition 330, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 331.0 in stage 0.0 (TID 331, ip-172-23-70-80.ec2.internal, executor 2, partition 331, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 206.0 in stage 0.0 (TID 206) in 304 ms on ip-172-23-70-80.ec2.internal (executor 2) (235/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 237.0 in stage 0.0 (TID 237) in 238 ms on ip-172-23-70-80.ec2.internal (executor 2) (236/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 235.0 in stage 0.0 (TID 235) in 245 ms on ip-172-23-70-80.ec2.internal (executor 2) (237/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 332.0 in stage 0.0 (TID 332, ip-172-23-70-80.ec2.internal, executor 2, partition 332, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 333.0 in stage 0.0 (TID 333, ip-172-23-70-80.ec2.internal, executor 2, partition 333, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 334.0 in stage 0.0 (TID 334, ip-172-23-70-80.ec2.internal, executor 2, partition 334, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 335.0 in stage 0.0 (TID 335, ip-172-23-70-80.ec2.internal, executor 2, partition 335, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 336.0 in stage 0.0 (TID 336, ip-172-23-70-80.ec2.internal, executor 2, partition 336, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 337.0 in stage 0.0 (TID 337, ip-172-23-70-80.ec2.internal, executor 2, partition 337, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 338.0 in stage 0.0 (TID 338, ip-172-23-70-80.ec2.internal, executor 2, partition 338, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 339.0 in stage 0.0 (TID 339, ip-172-23-70-80.ec2.internal, executor 2, partition 339, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 340.0 in stage 0.0 (TID 340, ip-172-23-70-80.ec2.internal, executor 2, partition 340, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 341.0 in stage 0.0 (TID 341, ip-172-23-70-80.ec2.internal, executor 2, partition 341, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 342.0 in stage 0.0 (TID 342, ip-172-23-75-58.ec2.internal, executor 1, partition 342, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 343.0 in stage 0.0 (TID 343, ip-172-23-75-58.ec2.internal, executor 1, partition 343, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 344.0 in stage 0.0 (TID 344, ip-172-23-75-58.ec2.internal, executor 1, partition 344, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 345.0 in stage 0.0 (TID 345, ip-172-23-75-58.ec2.internal, executor 1, partition 345, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 346.0 in stage 0.0 (TID 346, ip-172-23-75-58.ec2.internal, executor 1, partition 346, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 347.0 in stage 0.0 (TID 347, ip-172-23-75-58.ec2.internal, executor 1, partition 347, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 348.0 in stage 0.0 (TID 348, ip-172-23-75-58.ec2.internal, executor 1, partition 348, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 349.0 in stage 0.0 (TID 349, ip-172-23-75-58.ec2.internal, executor 1, partition 349, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 236.0 in stage 0.0 (TID 236) in 276 ms on ip-172-23-70-80.ec2.internal (executor 2) (238/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 243.0 in stage 0.0 (TID 243) in 249 ms on ip-172-23-70-80.ec2.internal (executor 2) (239/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 242.0 in stage 0.0 (TID 242) in 250 ms on ip-172-23-70-80.ec2.internal (executor 2) (240/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 248.0 in stage 0.0 (TID 248) in 225 ms on ip-172-23-70-80.ec2.internal (executor 2) (241/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 246.0 in stage 0.0 (TID 246) in 240 ms on ip-172-23-70-80.ec2.internal (executor 2) (242/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 239.0 in stage 0.0 (TID 239) in 270 ms on ip-172-23-70-80.ec2.internal (executor 2) (243/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 255.0 in stage 0.0 (TID 255) in 221 ms on ip-172-23-75-58.ec2.internal (executor 1) (244/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 251.0 in stage 0.0 (TID 251) in 224 ms on ip-172-23-75-58.ec2.internal (executor 1) (245/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 252.0 in stage 0.0 (TID 252) in 223 ms on ip-172-23-75-58.ec2.internal (executor 1) (246/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 256.0 in stage 0.0 (TID 256) in 213 ms on ip-172-23-75-58.ec2.internal (executor 1) (247/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 260.0 in stage 0.0 (TID 260) in 211 ms on ip-172-23-75-58.ec2.internal (executor 1) (248/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 253.0 in stage 0.0 (TID 253) in 223 ms on ip-172-23-75-58.ec2.internal (executor 1) (249/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 261.0 in stage 0.0 (TID 261) in 210 ms on ip-172-23-75-58.ec2.internal (executor 1) (250/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 257.0 in stage 0.0 (TID 257) in 212 ms on ip-172-23-75-58.ec2.internal (executor 1) (251/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 250.0 in stage 0.0 (TID 250) in 225 ms on ip-172-23-70-80.ec2.internal (executor 2) (252/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 244.0 in stage 0.0 (TID 244) in 249 ms on ip-172-23-70-80.ec2.internal (executor 2) (253/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 234.0 in stage 0.0 (TID 234) in 290 ms on ip-172-23-70-80.ec2.internal (executor 2) (254/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 350.0 in stage 0.0 (TID 350, ip-172-23-70-80.ec2.internal, executor 2, partition 350, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 351.0 in stage 0.0 (TID 351, ip-172-23-75-58.ec2.internal, executor 1, partition 351, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 352.0 in stage 0.0 (TID 352, ip-172-23-70-80.ec2.internal, executor 2, partition 352, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 353.0 in stage 0.0 (TID 353, ip-172-23-70-80.ec2.internal, executor 2, partition 353, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 247.0 in stage 0.0 (TID 247) in 244 ms on ip-172-23-70-80.ec2.internal (executor 2) (255/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 241.0 in stage 0.0 (TID 241) in 264 ms on ip-172-23-70-80.ec2.internal (executor 2) (256/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 238.0 in stage 0.0 (TID 238) in 283 ms on ip-172-23-70-80.ec2.internal (executor 2) (257/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 254.0 in stage 0.0 (TID 254) in 234 ms on ip-172-23-75-58.ec2.internal (executor 1) (258/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 245.0 in stage 0.0 (TID 245) in 258 ms on ip-172-23-70-80.ec2.internal (executor 2) (259/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 354.0 in stage 0.0 (TID 354, ip-172-23-70-80.ec2.internal, executor 2, partition 354, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 355.0 in stage 0.0 (TID 355, ip-172-23-70-80.ec2.internal, executor 2, partition 355, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 356.0 in stage 0.0 (TID 356, ip-172-23-75-58.ec2.internal, executor 1, partition 356, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 249.0 in stage 0.0 (TID 249) in 243 ms on ip-172-23-70-80.ec2.internal (executor 2) (260/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 259.0 in stage 0.0 (TID 259) in 229 ms on ip-172-23-75-58.ec2.internal (executor 1) (261/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 357.0 in stage 0.0 (TID 357, ip-172-23-75-58.ec2.internal, executor 1, partition 357, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 358.0 in stage 0.0 (TID 358, ip-172-23-75-58.ec2.internal, executor 1, partition 358, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 359.0 in stage 0.0 (TID 359, ip-172-23-75-58.ec2.internal, executor 1, partition 359, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 360.0 in stage 0.0 (TID 360, ip-172-23-75-58.ec2.internal, executor 1, partition 360, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 267.0 in stage 0.0 (TID 267) in 211 ms on ip-172-23-75-58.ec2.internal (executor 1) (262/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 263.0 in stage 0.0 (TID 263) in 213 ms on ip-172-23-75-58.ec2.internal (executor 1) (263/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 361.0 in stage 0.0 (TID 361, ip-172-23-75-58.ec2.internal, executor 1, partition 361, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 362.0 in stage 0.0 (TID 362, ip-172-23-75-58.ec2.internal, executor 1, partition 362, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 363.0 in stage 0.0 (TID 363, ip-172-23-75-58.ec2.internal, executor 1, partition 363, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 364.0 in stage 0.0 (TID 364, ip-172-23-75-58.ec2.internal, executor 1, partition 364, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 365.0 in stage 0.0 (TID 365, ip-172-23-75-58.ec2.internal, executor 1, partition 365, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 366.0 in stage 0.0 (TID 366, ip-172-23-75-58.ec2.internal, executor 1, partition 366, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 367.0 in stage 0.0 (TID 367, ip-172-23-75-58.ec2.internal, executor 1, partition 367, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 368.0 in stage 0.0 (TID 368, ip-172-23-75-58.ec2.internal, executor 1, partition 368, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 369.0 in stage 0.0 (TID 369, ip-172-23-75-58.ec2.internal, executor 1, partition 369, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 270.0 in stage 0.0 (TID 270) in 228 ms on ip-172-23-75-58.ec2.internal (executor 1) (264/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 271.0 in stage 0.0 (TID 271) in 228 ms on ip-172-23-75-58.ec2.internal (executor 1) (265/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 273.0 in stage 0.0 (TID 273) in 227 ms on ip-172-23-75-58.ec2.internal (executor 1) (266/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 265.0 in stage 0.0 (TID 265) in 231 ms on ip-172-23-75-58.ec2.internal (executor 1) (267/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 274.0 in stage 0.0 (TID 274) in 227 ms on ip-172-23-75-58.ec2.internal (executor 1) (268/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 268.0 in stage 0.0 (TID 268) in 230 ms on ip-172-23-75-58.ec2.internal (executor 1) (269/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 272.0 in stage 0.0 (TID 272) in 228 ms on ip-172-23-75-58.ec2.internal (executor 1) (270/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 275.0 in stage 0.0 (TID 275) in 214 ms on ip-172-23-75-58.ec2.internal (executor 1) (271/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 269.0 in stage 0.0 (TID 269) in 230 ms on ip-172-23-75-58.ec2.internal (executor 1) (272/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 262.0 in stage 0.0 (TID 262) in 256 ms on ip-172-23-75-58.ec2.internal (executor 1) (273/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 264.0 in stage 0.0 (TID 264) in 235 ms on ip-172-23-75-58.ec2.internal (executor 1) (274/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 370.0 in stage 0.0 (TID 370, ip-172-23-75-58.ec2.internal, executor 1, partition 370, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 371.0 in stage 0.0 (TID 371, ip-172-23-75-58.ec2.internal, executor 1, partition 371, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 279.0 in stage 0.0 (TID 279) in 195 ms on ip-172-23-75-58.ec2.internal (executor 1) (275/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 277.0 in stage 0.0 (TID 277) in 196 ms on ip-172-23-75-58.ec2.internal (executor 1) (276/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 372.0 in stage 0.0 (TID 372, ip-172-23-75-58.ec2.internal, executor 1, partition 372, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 373.0 in stage 0.0 (TID 373, ip-172-23-75-58.ec2.internal, executor 1, partition 373, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 374.0 in stage 0.0 (TID 374, ip-172-23-75-58.ec2.internal, executor 1, partition 374, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 375.0 in stage 0.0 (TID 375, ip-172-23-75-58.ec2.internal, executor 1, partition 375, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 376.0 in stage 0.0 (TID 376, ip-172-23-70-80.ec2.internal, executor 2, partition 376, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 377.0 in stage 0.0 (TID 377, ip-172-23-75-58.ec2.internal, executor 1, partition 377, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 378.0 in stage 0.0 (TID 378, ip-172-23-75-58.ec2.internal, executor 1, partition 378, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 276.0 in stage 0.0 (TID 276) in 203 ms on ip-172-23-75-58.ec2.internal (executor 1) (277/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 285.0 in stage 0.0 (TID 285) in 182 ms on ip-172-23-70-80.ec2.internal (executor 2) (278/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 283.0 in stage 0.0 (TID 283) in 184 ms on ip-172-23-75-58.ec2.internal (executor 1) (279/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 281.0 in stage 0.0 (TID 281) in 191 ms on ip-172-23-75-58.ec2.internal (executor 1) (280/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 266.0 in stage 0.0 (TID 266) in 243 ms on ip-172-23-75-58.ec2.internal (executor 1) (281/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 278.0 in stage 0.0 (TID 278) in 202 ms on ip-172-23-75-58.ec2.internal (executor 1) (282/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 280.0 in stage 0.0 (TID 280) in 201 ms on ip-172-23-75-58.ec2.internal (executor 1) (283/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 379.0 in stage 0.0 (TID 379, ip-172-23-75-58.ec2.internal, executor 1, partition 379, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 380.0 in stage 0.0 (TID 380, ip-172-23-70-80.ec2.internal, executor 2, partition 380, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 284.0 in stage 0.0 (TID 284) in 185 ms on ip-172-23-70-80.ec2.internal (executor 2) (284/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 282.0 in stage 0.0 (TID 282) in 192 ms on ip-172-23-75-58.ec2.internal (executor 1) (285/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 381.0 in stage 0.0 (TID 381, ip-172-23-75-58.ec2.internal, executor 1, partition 381, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 382.0 in stage 0.0 (TID 382, ip-172-23-75-58.ec2.internal, executor 1, partition 382, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 287.0 in stage 0.0 (TID 287) in 181 ms on ip-172-23-75-58.ec2.internal (executor 1) (286/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 286.0 in stage 0.0 (TID 286) in 183 ms on ip-172-23-75-58.ec2.internal (executor 1) (287/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 383.0 in stage 0.0 (TID 383, ip-172-23-70-80.ec2.internal, executor 2, partition 383, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 384.0 in stage 0.0 (TID 384, ip-172-23-70-80.ec2.internal, executor 2, partition 384, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 385.0 in stage 0.0 (TID 385, ip-172-23-75-58.ec2.internal, executor 1, partition 385, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 386.0 in stage 0.0 (TID 386, ip-172-23-70-80.ec2.internal, executor 2, partition 386, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 387.0 in stage 0.0 (TID 387, ip-172-23-70-80.ec2.internal, executor 2, partition 387, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 388.0 in stage 0.0 (TID 388, ip-172-23-75-58.ec2.internal, executor 1, partition 388, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 389.0 in stage 0.0 (TID 389, ip-172-23-70-80.ec2.internal, executor 2, partition 389, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 390.0 in stage 0.0 (TID 390, ip-172-23-75-58.ec2.internal, executor 1, partition 390, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 391.0 in stage 0.0 (TID 391, ip-172-23-70-80.ec2.internal, executor 2, partition 391, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 392.0 in stage 0.0 (TID 392, ip-172-23-75-58.ec2.internal, executor 1, partition 392, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 393.0 in stage 0.0 (TID 393, ip-172-23-75-58.ec2.internal, executor 1, partition 393, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 394.0 in stage 0.0 (TID 394, ip-172-23-70-80.ec2.internal, executor 2, partition 394, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 395.0 in stage 0.0 (TID 395, ip-172-23-70-80.ec2.internal, executor 2, partition 395, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 396.0 in stage 0.0 (TID 396, ip-172-23-75-58.ec2.internal, executor 1, partition 396, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 397.0 in stage 0.0 (TID 397, ip-172-23-70-80.ec2.internal, executor 2, partition 397, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 290.0 in stage 0.0 (TID 290) in 196 ms on ip-172-23-70-80.ec2.internal (executor 2) (288/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 298.0 in stage 0.0 (TID 298) in 185 ms on ip-172-23-70-80.ec2.internal (executor 2) (289/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 289.0 in stage 0.0 (TID 289) in 198 ms on ip-172-23-75-58.ec2.internal (executor 1) (290/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 297.0 in stage 0.0 (TID 297) in 187 ms on ip-172-23-70-80.ec2.internal (executor 2) (291/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 294.0 in stage 0.0 (TID 294) in 192 ms on ip-172-23-75-58.ec2.internal (executor 1) (292/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 296.0 in stage 0.0 (TID 296) in 188 ms on ip-172-23-70-80.ec2.internal (executor 2) (293/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 293.0 in stage 0.0 (TID 293) in 194 ms on ip-172-23-75-58.ec2.internal (executor 1) (294/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 295.0 in stage 0.0 (TID 295) in 191 ms on ip-172-23-75-58.ec2.internal (executor 1) (295/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 299.0 in stage 0.0 (TID 299) in 185 ms on ip-172-23-70-80.ec2.internal (executor 2) (296/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 301.0 in stage 0.0 (TID 301) in 184 ms on ip-172-23-70-80.ec2.internal (executor 2) (297/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 300.0 in stage 0.0 (TID 300) in 185 ms on ip-172-23-75-58.ec2.internal (executor 1) (298/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 304.0 in stage 0.0 (TID 304) in 178 ms on ip-172-23-70-80.ec2.internal (executor 2) (299/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 292.0 in stage 0.0 (TID 292) in 196 ms on ip-172-23-75-58.ec2.internal (executor 1) (300/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 288.0 in stage 0.0 (TID 288) in 200 ms on ip-172-23-70-80.ec2.internal (executor 2) (301/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 291.0 in stage 0.0 (TID 291) in 197 ms on ip-172-23-70-80.ec2.internal (executor 2) (302/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 398.0 in stage 0.0 (TID 398, ip-172-23-70-80.ec2.internal, executor 2, partition 398, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 399.0 in stage 0.0 (TID 399, ip-172-23-70-80.ec2.internal, executor 2, partition 399, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 400.0 in stage 0.0 (TID 400, ip-172-23-70-80.ec2.internal, executor 2, partition 400, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 401.0 in stage 0.0 (TID 401, ip-172-23-70-80.ec2.internal, executor 2, partition 401, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 305.0 in stage 0.0 (TID 305) in 183 ms on ip-172-23-70-80.ec2.internal (executor 2) (303/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 306.0 in stage 0.0 (TID 306) in 181 ms on ip-172-23-70-80.ec2.internal (executor 2) (304/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 302.0 in stage 0.0 (TID 302) in 189 ms on ip-172-23-70-80.ec2.internal (executor 2) (305/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 307.0 in stage 0.0 (TID 307) in 176 ms on ip-172-23-70-80.ec2.internal (executor 2) (306/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 402.0 in stage 0.0 (TID 402, ip-172-23-75-58.ec2.internal, executor 1, partition 402, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 303.0 in stage 0.0 (TID 303) in 197 ms on ip-172-23-75-58.ec2.internal (executor 1) (307/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 403.0 in stage 0.0 (TID 403, ip-172-23-70-80.ec2.internal, executor 2, partition 403, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 404.0 in stage 0.0 (TID 404, ip-172-23-75-58.ec2.internal, executor 1, partition 404, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 405.0 in stage 0.0 (TID 405, ip-172-23-75-58.ec2.internal, executor 1, partition 405, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 406.0 in stage 0.0 (TID 406, ip-172-23-75-58.ec2.internal, executor 1, partition 406, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 407.0 in stage 0.0 (TID 407, ip-172-23-75-58.ec2.internal, executor 1, partition 407, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 408.0 in stage 0.0 (TID 408, ip-172-23-75-58.ec2.internal, executor 1, partition 408, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 409.0 in stage 0.0 (TID 409, ip-172-23-70-80.ec2.internal, executor 2, partition 409, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 410.0 in stage 0.0 (TID 410, ip-172-23-70-80.ec2.internal, executor 2, partition 410, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 411.0 in stage 0.0 (TID 411, ip-172-23-70-80.ec2.internal, executor 2, partition 411, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 412.0 in stage 0.0 (TID 412, ip-172-23-70-80.ec2.internal, executor 2, partition 412, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 413.0 in stage 0.0 (TID 413, ip-172-23-70-80.ec2.internal, executor 2, partition 413, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 414.0 in stage 0.0 (TID 414, ip-172-23-75-58.ec2.internal, executor 1, partition 414, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 415.0 in stage 0.0 (TID 415, ip-172-23-70-80.ec2.internal, executor 2, partition 415, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 308.0 in stage 0.0 (TID 308) in 193 ms on ip-172-23-70-80.ec2.internal (executor 2) (308/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 309.0 in stage 0.0 (TID 309) in 192 ms on ip-172-23-75-58.ec2.internal (executor 1) (309/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 310.0 in stage 0.0 (TID 310) in 189 ms on ip-172-23-75-58.ec2.internal (executor 1) (310/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 313.0 in stage 0.0 (TID 313) in 182 ms on ip-172-23-75-58.ec2.internal (executor 1) (311/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 312.0 in stage 0.0 (TID 312) in 183 ms on ip-172-23-75-58.ec2.internal (executor 1) (312/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 311.0 in stage 0.0 (TID 311) in 187 ms on ip-172-23-75-58.ec2.internal (executor 1) (313/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 314.0 in stage 0.0 (TID 314) in 182 ms on ip-172-23-70-80.ec2.internal (executor 2) (314/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 315.0 in stage 0.0 (TID 315) in 177 ms on ip-172-23-70-80.ec2.internal (executor 2) (315/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 323.0 in stage 0.0 (TID 323) in 161 ms on ip-172-23-70-80.ec2.internal (executor 2) (316/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 320.0 in stage 0.0 (TID 320) in 162 ms on ip-172-23-70-80.ec2.internal (executor 2) (317/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 322.0 in stage 0.0 (TID 322) in 161 ms on ip-172-23-75-58.ec2.internal (executor 1) (318/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 317.0 in stage 0.0 (TID 317) in 164 ms on ip-172-23-70-80.ec2.internal (executor 2) (319/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 319.0 in stage 0.0 (TID 319) in 164 ms on ip-172-23-70-80.ec2.internal (executor 2) (320/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 416.0 in stage 0.0 (TID 416, ip-172-23-70-80.ec2.internal, executor 2, partition 416, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 417.0 in stage 0.0 (TID 417, ip-172-23-70-80.ec2.internal, executor 2, partition 417, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 418.0 in stage 0.0 (TID 418, ip-172-23-70-80.ec2.internal, executor 2, partition 418, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 419.0 in stage 0.0 (TID 419, ip-172-23-70-80.ec2.internal, executor 2, partition 419, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 420.0 in stage 0.0 (TID 420, ip-172-23-70-80.ec2.internal, executor 2, partition 420, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 421.0 in stage 0.0 (TID 421, ip-172-23-70-80.ec2.internal, executor 2, partition 421, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 321.0 in stage 0.0 (TID 321) in 172 ms on ip-172-23-70-80.ec2.internal (executor 2) (321/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 318.0 in stage 0.0 (TID 318) in 175 ms on ip-172-23-70-80.ec2.internal (executor 2) (322/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 316.0 in stage 0.0 (TID 316) in 176 ms on ip-172-23-70-80.ec2.internal (executor 2) (323/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 324.0 in stage 0.0 (TID 324) in 165 ms on ip-172-23-70-80.ec2.internal (executor 2) (324/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 327.0 in stage 0.0 (TID 327) in 163 ms on ip-172-23-70-80.ec2.internal (executor 2) (325/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 326.0 in stage 0.0 (TID 326) in 164 ms on ip-172-23-70-80.ec2.internal (executor 2) (326/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 422.0 in stage 0.0 (TID 422, ip-172-23-70-80.ec2.internal, executor 2, partition 422, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 423.0 in stage 0.0 (TID 423, ip-172-23-70-80.ec2.internal, executor 2, partition 423, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 424.0 in stage 0.0 (TID 424, ip-172-23-70-80.ec2.internal, executor 2, partition 424, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 425.0 in stage 0.0 (TID 425, ip-172-23-70-80.ec2.internal, executor 2, partition 425, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 426.0 in stage 0.0 (TID 426, ip-172-23-70-80.ec2.internal, executor 2, partition 426, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 427.0 in stage 0.0 (TID 427, ip-172-23-70-80.ec2.internal, executor 2, partition 427, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 428.0 in stage 0.0 (TID 428, ip-172-23-70-80.ec2.internal, executor 2, partition 428, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 429.0 in stage 0.0 (TID 429, ip-172-23-70-80.ec2.internal, executor 2, partition 429, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 325.0 in stage 0.0 (TID 325) in 184 ms on ip-172-23-70-80.ec2.internal (executor 2) (327/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 331.0 in stage 0.0 (TID 331) in 175 ms on ip-172-23-70-80.ec2.internal (executor 2) (328/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 330.0 in stage 0.0 (TID 330) in 176 ms on ip-172-23-70-80.ec2.internal (executor 2) (329/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 334.0 in stage 0.0 (TID 334) in 167 ms on ip-172-23-70-80.ec2.internal (executor 2) (330/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 333.0 in stage 0.0 (TID 333) in 173 ms on ip-172-23-70-80.ec2.internal (executor 2) (331/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 430.0 in stage 0.0 (TID 430, ip-172-23-70-80.ec2.internal, executor 2, partition 430, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 332.0 in stage 0.0 (TID 332) in 175 ms on ip-172-23-70-80.ec2.internal (executor 2) (332/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 337.0 in stage 0.0 (TID 337) in 163 ms on ip-172-23-70-80.ec2.internal (executor 2) (333/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 329.0 in stage 0.0 (TID 329) in 179 ms on ip-172-23-70-80.ec2.internal (executor 2) (334/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 328.0 in stage 0.0 (TID 328) in 185 ms on ip-172-23-70-80.ec2.internal (executor 2) (335/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 431.0 in stage 0.0 (TID 431, ip-172-23-70-80.ec2.internal, executor 2, partition 431, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 432.0 in stage 0.0 (TID 432, ip-172-23-70-80.ec2.internal, executor 2, partition 432, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 433.0 in stage 0.0 (TID 433, ip-172-23-70-80.ec2.internal, executor 2, partition 433, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 434.0 in stage 0.0 (TID 434, ip-172-23-70-80.ec2.internal, executor 2, partition 434, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 336.0 in stage 0.0 (TID 336) in 169 ms on ip-172-23-70-80.ec2.internal (executor 2) (336/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 340.0 in stage 0.0 (TID 340) in 161 ms on ip-172-23-70-80.ec2.internal (executor 2) (337/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 335.0 in stage 0.0 (TID 335) in 173 ms on ip-172-23-70-80.ec2.internal (executor 2) (338/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 338.0 in stage 0.0 (TID 338) in 165 ms on ip-172-23-70-80.ec2.internal (executor 2) (339/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 435.0 in stage 0.0 (TID 435, ip-172-23-70-80.ec2.internal, executor 2, partition 435, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 436.0 in stage 0.0 (TID 436, ip-172-23-75-58.ec2.internal, executor 1, partition 436, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 437.0 in stage 0.0 (TID 437, ip-172-23-75-58.ec2.internal, executor 1, partition 437, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 438.0 in stage 0.0 (TID 438, ip-172-23-75-58.ec2.internal, executor 1, partition 438, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 345.0 in stage 0.0 (TID 345) in 160 ms on ip-172-23-75-58.ec2.internal (executor 1) (340/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 346.0 in stage 0.0 (TID 346) in 159 ms on ip-172-23-75-58.ec2.internal (executor 1) (341/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 341.0 in stage 0.0 (TID 341) in 166 ms on ip-172-23-70-80.ec2.internal (executor 2) (342/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 439.0 in stage 0.0 (TID 439, ip-172-23-75-58.ec2.internal, executor 1, partition 439, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 440.0 in stage 0.0 (TID 440, ip-172-23-75-58.ec2.internal, executor 1, partition 440, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 342.0 in stage 0.0 (TID 342) in 171 ms on ip-172-23-75-58.ec2.internal (executor 1) (343/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 344.0 in stage 0.0 (TID 344) in 169 ms on ip-172-23-75-58.ec2.internal (executor 1) (344/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 343.0 in stage 0.0 (TID 343) in 171 ms on ip-172-23-75-58.ec2.internal (executor 1) (345/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 441.0 in stage 0.0 (TID 441, ip-172-23-75-58.ec2.internal, executor 1, partition 441, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 442.0 in stage 0.0 (TID 442, ip-172-23-75-58.ec2.internal, executor 1, partition 442, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 443.0 in stage 0.0 (TID 443, ip-172-23-70-80.ec2.internal, executor 2, partition 443, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 444.0 in stage 0.0 (TID 444, ip-172-23-70-80.ec2.internal, executor 2, partition 444, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 445.0 in stage 0.0 (TID 445, ip-172-23-70-80.ec2.internal, executor 2, partition 445, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 446.0 in stage 0.0 (TID 446, ip-172-23-75-58.ec2.internal, executor 1, partition 446, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 347.0 in stage 0.0 (TID 347) in 182 ms on ip-172-23-75-58.ec2.internal (executor 1) (346/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 352.0 in stage 0.0 (TID 352) in 166 ms on ip-172-23-70-80.ec2.internal (executor 2) (347/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 258.0 in stage 0.0 (TID 258) in 387 ms on ip-172-23-75-58.ec2.internal (executor 1) (348/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 348.0 in stage 0.0 (TID 348) in 179 ms on ip-172-23-75-58.ec2.internal (executor 1) (349/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 447.0 in stage 0.0 (TID 447, ip-172-23-75-58.ec2.internal, executor 1, partition 447, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 339.0 in stage 0.0 (TID 339) in 193 ms on ip-172-23-70-80.ec2.internal (executor 2) (350/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 349.0 in stage 0.0 (TID 349) in 180 ms on ip-172-23-75-58.ec2.internal (executor 1) (351/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 350.0 in stage 0.0 (TID 350) in 176 ms on ip-172-23-70-80.ec2.internal (executor 2) (352/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 448.0 in stage 0.0 (TID 448, ip-172-23-70-80.ec2.internal, executor 2, partition 448, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 449.0 in stage 0.0 (TID 449, ip-172-23-75-58.ec2.internal, executor 1, partition 449, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 450.0 in stage 0.0 (TID 450, ip-172-23-70-80.ec2.internal, executor 2, partition 450, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 451.0 in stage 0.0 (TID 451, ip-172-23-70-80.ec2.internal, executor 2, partition 451, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 452.0 in stage 0.0 (TID 452, ip-172-23-75-58.ec2.internal, executor 1, partition 452, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 453.0 in stage 0.0 (TID 453, ip-172-23-75-58.ec2.internal, executor 1, partition 453, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 454.0 in stage 0.0 (TID 454, ip-172-23-75-58.ec2.internal, executor 1, partition 454, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 455.0 in stage 0.0 (TID 455, ip-172-23-75-58.ec2.internal, executor 1, partition 455, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 355.0 in stage 0.0 (TID 355) in 183 ms on ip-172-23-70-80.ec2.internal (executor 2) (353/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 358.0 in stage 0.0 (TID 358) in 179 ms on ip-172-23-75-58.ec2.internal (executor 1) (354/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 456.0 in stage 0.0 (TID 456, ip-172-23-75-58.ec2.internal, executor 1, partition 456, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 354.0 in stage 0.0 (TID 354) in 185 ms on ip-172-23-70-80.ec2.internal (executor 2) (355/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 362.0 in stage 0.0 (TID 362) in 172 ms on ip-172-23-75-58.ec2.internal (executor 1) (356/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 357.0 in stage 0.0 (TID 357) in 181 ms on ip-172-23-75-58.ec2.internal (executor 1) (357/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 353.0 in stage 0.0 (TID 353) in 191 ms on ip-172-23-70-80.ec2.internal (executor 2) (358/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 351.0 in stage 0.0 (TID 351) in 193 ms on ip-172-23-75-58.ec2.internal (executor 1) (359/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 360.0 in stage 0.0 (TID 360) in 180 ms on ip-172-23-75-58.ec2.internal (executor 1) (360/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 457.0 in stage 0.0 (TID 457, ip-172-23-75-58.ec2.internal, executor 1, partition 457, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 356.0 in stage 0.0 (TID 356) in 186 ms on ip-172-23-75-58.ec2.internal (executor 1) (361/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 361.0 in stage 0.0 (TID 361) in 176 ms on ip-172-23-75-58.ec2.internal (executor 1) (362/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 458.0 in stage 0.0 (TID 458, ip-172-23-75-58.ec2.internal, executor 1, partition 458, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 359.0 in stage 0.0 (TID 359) in 183 ms on ip-172-23-75-58.ec2.internal (executor 1) (363/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 459.0 in stage 0.0 (TID 459, ip-172-23-75-58.ec2.internal, executor 1, partition 459, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 366.0 in stage 0.0 (TID 366) in 166 ms on ip-172-23-75-58.ec2.internal (executor 1) (364/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 460.0 in stage 0.0 (TID 460, ip-172-23-75-58.ec2.internal, executor 1, partition 460, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 364.0 in stage 0.0 (TID 364) in 168 ms on ip-172-23-75-58.ec2.internal (executor 1) (365/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 461.0 in stage 0.0 (TID 461, ip-172-23-75-58.ec2.internal, executor 1, partition 461, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 367.0 in stage 0.0 (TID 367) in 167 ms on ip-172-23-75-58.ec2.internal (executor 1) (366/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 462.0 in stage 0.0 (TID 462, ip-172-23-75-58.ec2.internal, executor 1, partition 462, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 363.0 in stage 0.0 (TID 363) in 182 ms on ip-172-23-75-58.ec2.internal (executor 1) (367/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 463.0 in stage 0.0 (TID 463, ip-172-23-75-58.ec2.internal, executor 1, partition 463, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 365.0 in stage 0.0 (TID 365) in 171 ms on ip-172-23-75-58.ec2.internal (executor 1) (368/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 464.0 in stage 0.0 (TID 464, ip-172-23-75-58.ec2.internal, executor 1, partition 464, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 369.0 in stage 0.0 (TID 369) in 170 ms on ip-172-23-75-58.ec2.internal (executor 1) (369/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 465.0 in stage 0.0 (TID 465, ip-172-23-75-58.ec2.internal, executor 1, partition 465, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 368.0 in stage 0.0 (TID 368) in 173 ms on ip-172-23-75-58.ec2.internal (executor 1) (370/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 466.0 in stage 0.0 (TID 466, ip-172-23-75-58.ec2.internal, executor 1, partition 466, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 374.0 in stage 0.0 (TID 374) in 164 ms on ip-172-23-75-58.ec2.internal (executor 1) (371/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 467.0 in stage 0.0 (TID 467, ip-172-23-75-58.ec2.internal, executor 1, partition 467, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 373.0 in stage 0.0 (TID 373) in 167 ms on ip-172-23-75-58.ec2.internal (executor 1) (372/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 468.0 in stage 0.0 (TID 468, ip-172-23-75-58.ec2.internal, executor 1, partition 468, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 370.0 in stage 0.0 (TID 370) in 171 ms on ip-172-23-75-58.ec2.internal (executor 1) (373/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 469.0 in stage 0.0 (TID 469, ip-172-23-75-58.ec2.internal, executor 1, partition 469, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 470.0 in stage 0.0 (TID 470, ip-172-23-75-58.ec2.internal, executor 1, partition 470, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 372.0 in stage 0.0 (TID 372) in 174 ms on ip-172-23-75-58.ec2.internal (executor 1) (374/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 375.0 in stage 0.0 (TID 375) in 172 ms on ip-172-23-75-58.ec2.internal (executor 1) (375/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 471.0 in stage 0.0 (TID 471, ip-172-23-75-58.ec2.internal, executor 1, partition 471, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 377.0 in stage 0.0 (TID 377) in 174 ms on ip-172-23-75-58.ec2.internal (executor 1) (376/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 472.0 in stage 0.0 (TID 472, ip-172-23-75-58.ec2.internal, executor 1, partition 472, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 371.0 in stage 0.0 (TID 371) in 179 ms on ip-172-23-75-58.ec2.internal (executor 1) (377/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 473.0 in stage 0.0 (TID 473, ip-172-23-75-58.ec2.internal, executor 1, partition 473, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 378.0 in stage 0.0 (TID 378) in 180 ms on ip-172-23-75-58.ec2.internal (executor 1) (378/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 474.0 in stage 0.0 (TID 474, ip-172-23-70-80.ec2.internal, executor 2, partition 474, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 475.0 in stage 0.0 (TID 475, ip-172-23-75-58.ec2.internal, executor 1, partition 475, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 476.0 in stage 0.0 (TID 476, ip-172-23-75-58.ec2.internal, executor 1, partition 476, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 477.0 in stage 0.0 (TID 477, ip-172-23-70-80.ec2.internal, executor 2, partition 477, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 478.0 in stage 0.0 (TID 478, ip-172-23-70-80.ec2.internal, executor 2, partition 478, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 479.0 in stage 0.0 (TID 479, ip-172-23-75-58.ec2.internal, executor 1, partition 479, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 480.0 in stage 0.0 (TID 480, ip-172-23-75-58.ec2.internal, executor 1, partition 480, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 481.0 in stage 0.0 (TID 481, ip-172-23-75-58.ec2.internal, executor 1, partition 481, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 482.0 in stage 0.0 (TID 482, ip-172-23-75-58.ec2.internal, executor 1, partition 482, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 483.0 in stage 0.0 (TID 483, ip-172-23-70-80.ec2.internal, executor 2, partition 483, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 484.0 in stage 0.0 (TID 484, ip-172-23-70-80.ec2.internal, executor 2, partition 484, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 485.0 in stage 0.0 (TID 485, ip-172-23-75-58.ec2.internal, executor 1, partition 485, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 376.0 in stage 0.0 (TID 376) in 195 ms on ip-172-23-70-80.ec2.internal (executor 2) (379/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 380.0 in stage 0.0 (TID 380) in 190 ms on ip-172-23-70-80.ec2.internal (executor 2) (380/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 379.0 in stage 0.0 (TID 379) in 190 ms on ip-172-23-75-58.ec2.internal (executor 1) (381/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 383.0 in stage 0.0 (TID 383) in 182 ms on ip-172-23-70-80.ec2.internal (executor 2) (382/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 381.0 in stage 0.0 (TID 381) in 189 ms on ip-172-23-75-58.ec2.internal (executor 1) (383/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 392.0 in stage 0.0 (TID 392) in 175 ms on ip-172-23-75-58.ec2.internal (executor 1) (384/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 387.0 in stage 0.0 (TID 387) in 181 ms on ip-172-23-70-80.ec2.internal (executor 2) (385/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 394.0 in stage 0.0 (TID 394) in 174 ms on ip-172-23-70-80.ec2.internal (executor 2) (386/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 388.0 in stage 0.0 (TID 388) in 178 ms on ip-172-23-75-58.ec2.internal (executor 1) (387/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 382.0 in stage 0.0 (TID 382) in 190 ms on ip-172-23-75-58.ec2.internal (executor 1) (388/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 385.0 in stage 0.0 (TID 385) in 182 ms on ip-172-23-75-58.ec2.internal (executor 1) (389/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 390.0 in stage 0.0 (TID 390) in 177 ms on ip-172-23-75-58.ec2.internal (executor 1) (390/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 486.0 in stage 0.0 (TID 486, ip-172-23-70-80.ec2.internal, executor 2, partition 486, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 397.0 in stage 0.0 (TID 397) in 173 ms on ip-172-23-70-80.ec2.internal (executor 2) (391/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 487.0 in stage 0.0 (TID 487, ip-172-23-75-58.ec2.internal, executor 1, partition 487, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 402.0 in stage 0.0 (TID 402) in 165 ms on ip-172-23-75-58.ec2.internal (executor 1) (392/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 488.0 in stage 0.0 (TID 488, ip-172-23-75-58.ec2.internal, executor 1, partition 488, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 404.0 in stage 0.0 (TID 404) in 158 ms on ip-172-23-75-58.ec2.internal (executor 1) (393/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 489.0 in stage 0.0 (TID 489, ip-172-23-70-80.ec2.internal, executor 2, partition 489, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 410.0 in stage 0.0 (TID 410) in 156 ms on ip-172-23-70-80.ec2.internal (executor 2) (394/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 490.0 in stage 0.0 (TID 490, ip-172-23-70-80.ec2.internal, executor 2, partition 490, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 413.0 in stage 0.0 (TID 413) in 161 ms on ip-172-23-70-80.ec2.internal (executor 2) (395/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 491.0 in stage 0.0 (TID 491, ip-172-23-70-80.ec2.internal, executor 2, partition 491, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 492.0 in stage 0.0 (TID 492, ip-172-23-75-58.ec2.internal, executor 1, partition 492, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 400.0 in stage 0.0 (TID 400) in 184 ms on ip-172-23-70-80.ec2.internal (executor 2) (396/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 493.0 in stage 0.0 (TID 493, ip-172-23-75-58.ec2.internal, executor 1, partition 493, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 393.0 in stage 0.0 (TID 393) in 197 ms on ip-172-23-75-58.ec2.internal (executor 1) (397/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 396.0 in stage 0.0 (TID 396) in 193 ms on ip-172-23-75-58.ec2.internal (executor 1) (398/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 494.0 in stage 0.0 (TID 494, ip-172-23-70-80.ec2.internal, executor 2, partition 494, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 415.0 in stage 0.0 (TID 415) in 165 ms on ip-172-23-70-80.ec2.internal (executor 2) (399/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 495.0 in stage 0.0 (TID 495, ip-172-23-70-80.ec2.internal, executor 2, partition 495, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 496.0 in stage 0.0 (TID 496, ip-172-23-70-80.ec2.internal, executor 2, partition 496, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 409.0 in stage 0.0 (TID 409) in 169 ms on ip-172-23-70-80.ec2.internal (executor 2) (400/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 395.0 in stage 0.0 (TID 395) in 197 ms on ip-172-23-70-80.ec2.internal (executor 2) (401/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 497.0 in stage 0.0 (TID 497, ip-172-23-70-80.ec2.internal, executor 2, partition 497, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 391.0 in stage 0.0 (TID 391) in 201 ms on ip-172-23-70-80.ec2.internal (executor 2) (402/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 498.0 in stage 0.0 (TID 498, ip-172-23-70-80.ec2.internal, executor 2, partition 498, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 401.0 in stage 0.0 (TID 401) in 189 ms on ip-172-23-70-80.ec2.internal (executor 2) (403/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Starting task 499.0 in stage 0.0 (TID 499, ip-172-23-70-80.ec2.internal, executor 2, partition 499, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 386.0 in stage 0.0 (TID 386) in 210 ms on ip-172-23-70-80.ec2.internal (executor 2) (404/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 405.0 in stage 0.0 (TID 405) in 192 ms on ip-172-23-75-58.ec2.internal (executor 1) (405/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 408.0 in stage 0.0 (TID 408) in 191 ms on ip-172-23-75-58.ec2.internal (executor 1) (406/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 407.0 in stage 0.0 (TID 407) in 191 ms on ip-172-23-75-58.ec2.internal (executor 1) (407/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 414.0 in stage 0.0 (TID 414) in 186 ms on ip-172-23-75-58.ec2.internal (executor 1) (408/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 399.0 in stage 0.0 (TID 399) in 209 ms on ip-172-23-70-80.ec2.internal (executor 2) (409/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 398.0 in stage 0.0 (TID 398) in 211 ms on ip-172-23-70-80.ec2.internal (executor 2) (410/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 412.0 in stage 0.0 (TID 412) in 188 ms on ip-172-23-70-80.ec2.internal (executor 2) (411/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 389.0 in stage 0.0 (TID 389) in 223 ms on ip-172-23-70-80.ec2.internal (executor 2) (412/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 418.0 in stage 0.0 (TID 418) in 179 ms on ip-172-23-70-80.ec2.internal (executor 2) (413/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 403.0 in stage 0.0 (TID 403) in 195 ms on ip-172-23-70-80.ec2.internal (executor 2) (414/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 417.0 in stage 0.0 (TID 417) in 180 ms on ip-172-23-70-80.ec2.internal (executor 2) (415/500) 2022-04-01 03:25:04 TaskSetManager: INFO: Finished task 411.0 in stage 0.0 (TID 411) in 189 ms on 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Coerced almost-sorted dataset 2022-04-01 03:25:04 root: INFO: Unsorted keys: CURRENT={ locus: { contig: chr1, position: 92478757 }, alleles: [2; CAGAGAG, C] }, PREV={ locus: { contig: chr1, position: 92478757 }, alleles: [2; CAGAGAG, CAGAGAGAGAGAGAGAG] } 2022-04-01 03:25:05 root: INFO: keysIfOneToOne struct{locus: locus, alleles: array} RVDPartitioner(struct{locus: locus, alleles: array}, [[[chr1:9710632]-[chr1:64845433]], [[chr1:64845434]-[chr2:32240318]], [[chr2:32240401]-[chr4:56493864]], [[chr4:56493939]-[chr5:68239961]], [[chr5:68239982]-[chr7:2926700]], [[chr7:2926811]-[chr10:89003044]], [[chr10:89003139]-[chr15:77035630]], [[chr15:77035767]-[chr16:81939869]], [[chr16:81956900]-[chr17:80184162]], [[chr17:80184196]-[chr19:53804068]], [[chr19:53805300]-[chrX:47206504]], [[chrX:47209889]-[chrX:154776873]]]) 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- Verify : 0.079ms, total 4.061s 2022-04-01 03:25:05 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 15: (Coalesce (Let __iruid_15 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1)) (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1))) (InsertFields (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1) None (locus (GetField locus (Ref __iruid_15))) (alleles (GetField alleles (Ref __iruid_15))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String]} (Str "Internal e..."))) 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.599ms, total 4.063s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.122ms, total 4.064s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.611ms, total 4.064s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 3.480ms, total 4.068s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.156ms, total 4.068s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 4.397ms, total 4.073s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.268ms, total 4.073s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.112ms, total 4.074s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.305ms, total 4.075s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 1.498ms, total 4.077s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.129ms, total 4.077s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.188ms, total 4.078s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.280ms, total 4.079s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.099ms, total 4.079s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.204ms, total 4.079s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 1.460ms, total 4.081s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.126ms, total 4.081s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.218ms, total 4.082s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 19.861ms, total 4.083s, tagged coverage 81.8 2022-04-01 03:25:05 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 15: (Coalesce (Let __iruid_19 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1)) (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1))) (InsertFields (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1) None (locus (GetField locus (Ref __iruid_19))) (alleles (GetField alleles (Ref __iruid_19))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String]} (Str "Internal e..."))) 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation : 22.159ms, total 4.083s, tagged coverage 73.3 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- Verify : 0.027ms, total 4.084s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR : 22.858ms, total 4.084s, tagged coverage 71.6 2022-04-01 03:25:05 root: INFO: Timer: Time taken for InlineApplyIR -- Verify : 0.055ms, total 4.085s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for InlineApplyIR -- LoweringTransformation : 0.463ms, total 4.085s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for InlineApplyIR -- Verify : 0.058ms, total 4.086s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for InlineApplyIR : 0.969ms, total 4.086s, tagged coverage 59.4 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- Verify : 0.024ms, total 4.086s 2022-04-01 03:25:05 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 15: (Coalesce (Let __iruid_19 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1)) (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1))) (InsertFields (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1) None (locus (GetField locus (Ref __iruid_19))) (alleles (GetField alleles (Ref __iruid_19))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String]} (Str "Internal e..."))) 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.191ms, total 4.087s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.106ms, total 4.087s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.210ms, total 4.088s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 1.403ms, total 4.089s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.133ms, total 4.090s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.236ms, total 4.091s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.225ms, total 4.091s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.102ms, total 4.092s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.205ms, total 4.092s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 1.461ms, total 4.094s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.125ms, total 4.094s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.535ms, total 4.095s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.228ms, total 4.096s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.098ms, total 4.096s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.204ms, total 4.096s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 1.957ms, total 4.099s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.126ms, total 4.099s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.077ms, total 4.100s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 13.432ms, total 4.100s, tagged coverage 79.1 2022-04-01 03:25:05 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 15: (Coalesce (Let __iruid_22 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1)) (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1))) (InsertFields (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1) None (locus (GetField locus (Ref __iruid_22))) (alleles (GetField alleles (Ref __iruid_22))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String]} (Str "Internal e..."))) 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 15.080ms, total 4.101s, tagged coverage 70.4 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- Verify : 0.028ms, total 4.101s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR : 15.540ms, total 4.102s, tagged coverage 68.7 2022-04-01 03:25:05 root: INFO: Timer: Time taken for LowerArrayAggsToRunAggs -- Verify : 0.058ms, total 4.103s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for LowerArrayAggsToRunAggs -- LoweringTransformation : 4.758ms, total 4.108s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for LowerArrayAggsToRunAggs -- Verify : 0.338ms, total 4.108s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for LowerArrayAggsToRunAggs : 5.618ms, total 4.108s, tagged coverage 91.8 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.024ms, total 4.109s 2022-04-01 03:25:05 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 15: (Coalesce (Let __iruid_22 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1)) (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1))) (InsertFields (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1) None (locus (GetField locus (Ref __iruid_22))) (alleles (GetField alleles (Ref __iruid_22))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String]} (Str "Internal e..."))) 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.190ms, total 4.110s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.112ms, total 4.110s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.255ms, total 4.110s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 1.320ms, total 4.112s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.135ms, total 4.112s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.073ms, total 4.113s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.238ms, total 4.114s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.101ms, total 4.114s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.201ms, total 4.114s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 1.278ms, total 4.116s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.134ms, total 4.116s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.224ms, total 4.117s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.239ms, total 4.118s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.105ms, total 4.118s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.206ms, total 4.118s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 1.239ms, total 4.120s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.130ms, total 4.120s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.098ms, total 4.121s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 11.865ms, total 4.121s, tagged coverage 78.2 2022-04-01 03:25:05 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 15: (Coalesce (Let __iruid_25 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1)) (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1))) (InsertFields (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString]} 1) None (locus (GetField locus (Ref __iruid_25))) (alleles (GetField alleles (Ref __iruid_25))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String]} (Str "Internal e..."))) 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 13.546ms, total 4.122s, tagged coverage 68.5 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.027ms, total 4.122s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs : 14.021ms, total 4.123s, tagged coverage 66.5 2022-04-01 03:25:05 root: INFO: encoder cache miss (0 hits, 1 misses, 0.000) 2022-04-01 03:25:05 root: INFO: instruction count: 6: __C31etypeEncode. 2022-04-01 03:25:05 root: INFO: instruction count: 8: __C31etypeEncode.apply 2022-04-01 03:25:05 root: INFO: instruction count: 16: __C31etypeEncode.__m32ENCODE_r_tuple_of_r_stringEND_TO_r_struct_of_r_binaryEND 2022-04-01 03:25:05 root: INFO: instruction count: 19: __C31etypeEncode.__m33ENCODE_r_binary_TO_r_binary 2022-04-01 03:25:05 MemoryStore: INFO: Block broadcast_3 stored as values in memory (estimated size 104.0 B, free 5.6 GB) 2022-04-01 03:25:05 MemoryStore: INFO: Block broadcast_3_piece0 stored as bytes in memory (estimated size 109.0 B, free 5.6 GB) 2022-04-01 03:25:05 BlockManagerInfo: INFO: Added broadcast_3_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 109.0 B, free: 5.6 GB) 2022-04-01 03:25:05 SparkContext: INFO: Created broadcast 3 from broadcast at SparkBackend.scala:233 2022-04-01 03:25:05 root: INFO: instruction count: 6: __C1Compiled. 2022-04-01 03:25:05 root: INFO: instruction count: 94: __C1Compiled.apply 2022-04-01 03:25:05 root: INFO: instruction count: 276: __C1Compiled.__m4min_rep 2022-04-01 03:25:05 root: INFO: instruction count: 15: __C1Compiled.__m7setup_null 2022-04-01 03:25:05 root: INFO: instruction count: 11: __C1Compiled.__m22addIRIntermediate 2022-04-01 03:25:05 root: INFO: instruction count: 8: __C1Compiled.__m23addIRIntermediate 2022-04-01 03:25:05 root: INFO: instruction count: 14: __C1Compiled.setPartitionIndex 2022-04-01 03:25:05 root: INFO: instruction count: 7: __C1Compiled.addPartitionRegion 2022-04-01 03:25:05 root: INFO: instruction count: 25: __C1Compiled.__m27DECODE_r_struct_of_r_binaryEND_TO_r_tuple_of_r_stringEND 2022-04-01 03:25:05 root: INFO: instruction count: 11: __C1Compiled.__m28read_fields_group_0 2022-04-01 03:25:05 root: INFO: instruction count: 34: __C1Compiled.__m29INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:05 root: INFO: instruction count: 41: __C1Compiled.addLiterals 2022-04-01 03:25:05 SparkContext: INFO: Starting job: runJob at ContextRDD.scala:228 2022-04-01 03:25:05 DAGScheduler: INFO: Got job 1 (runJob at ContextRDD.scala:228) with 12 output partitions 2022-04-01 03:25:05 DAGScheduler: INFO: Final stage: ResultStage 1 (runJob at ContextRDD.scala:228) 2022-04-01 03:25:05 DAGScheduler: INFO: Parents of final stage: List() 2022-04-01 03:25:05 DAGScheduler: INFO: Missing parents: List() 2022-04-01 03:25:05 DAGScheduler: INFO: Submitting ResultStage 1 (MapPartitionsRDD[8] at mapPartitions at ContextRDD.scala:212), which has no missing parents 2022-04-01 03:25:05 MemoryStore: INFO: Block broadcast_4 stored as values in memory (estimated size 150.9 KB, free 5.6 GB) 2022-04-01 03:25:05 MemoryStore: INFO: Block broadcast_4_piece0 stored as bytes in memory (estimated size 52.6 KB, free 5.6 GB) 2022-04-01 03:25:05 BlockManagerInfo: INFO: Added broadcast_4_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 52.6 KB, free: 5.6 GB) 2022-04-01 03:25:05 SparkContext: INFO: Created broadcast 4 from broadcast at DAGScheduler.scala:1280 2022-04-01 03:25:05 DAGScheduler: INFO: Submitting 12 missing tasks from ResultStage 1 (MapPartitionsRDD[8] at mapPartitions at ContextRDD.scala:212) (first 15 tasks are for partitions Vector(0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11)) 2022-04-01 03:25:05 YarnScheduler: INFO: Adding task set 1.0 with 12 tasks 2022-04-01 03:25:05 TaskSetManager: INFO: Starting task 0.0 in stage 1.0 (TID 500, ip-172-23-75-58.ec2.internal, executor 1, partition 0, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:05 TaskSetManager: INFO: Starting task 1.0 in stage 1.0 (TID 501, ip-172-23-70-80.ec2.internal, executor 2, partition 1, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:05 TaskSetManager: INFO: Starting task 2.0 in stage 1.0 (TID 502, ip-172-23-75-58.ec2.internal, executor 1, partition 2, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:05 TaskSetManager: INFO: Starting task 3.0 in stage 1.0 (TID 503, ip-172-23-70-80.ec2.internal, executor 2, partition 3, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:05 TaskSetManager: INFO: Starting task 4.0 in stage 1.0 (TID 504, ip-172-23-75-58.ec2.internal, executor 1, partition 4, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:05 TaskSetManager: INFO: Starting task 5.0 in stage 1.0 (TID 505, ip-172-23-70-80.ec2.internal, executor 2, partition 5, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:05 TaskSetManager: INFO: Starting task 6.0 in stage 1.0 (TID 506, ip-172-23-75-58.ec2.internal, executor 1, partition 6, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:05 TaskSetManager: INFO: Starting task 7.0 in stage 1.0 (TID 507, ip-172-23-70-80.ec2.internal, executor 2, partition 7, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:05 TaskSetManager: INFO: Starting task 8.0 in stage 1.0 (TID 508, ip-172-23-75-58.ec2.internal, executor 1, partition 8, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:05 TaskSetManager: INFO: Starting task 9.0 in stage 1.0 (TID 509, ip-172-23-70-80.ec2.internal, executor 2, partition 9, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:05 TaskSetManager: INFO: Starting task 10.0 in stage 1.0 (TID 510, ip-172-23-75-58.ec2.internal, executor 1, partition 10, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:05 TaskSetManager: INFO: Starting task 11.0 in stage 1.0 (TID 511, ip-172-23-70-80.ec2.internal, executor 2, partition 11, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:05 BlockManagerInfo: INFO: Added broadcast_4_piece0 in memory on ip-172-23-70-80.ec2.internal:37501 (size: 52.6 KB, free: 181.7 GB) 2022-04-01 03:25:05 BlockManagerInfo: INFO: Added broadcast_4_piece0 in memory on ip-172-23-75-58.ec2.internal:40133 (size: 52.6 KB, free: 181.7 GB) 2022-04-01 03:25:05 BlockManagerInfo: INFO: Added broadcast_3_piece0 in memory on ip-172-23-70-80.ec2.internal:37501 (size: 109.0 B, free: 181.7 GB) 2022-04-01 03:25:05 BlockManagerInfo: INFO: Added broadcast_3_piece0 in memory on ip-172-23-75-58.ec2.internal:40133 (size: 109.0 B, free: 181.7 GB) 2022-04-01 03:25:05 TaskSetManager: INFO: Finished task 11.0 in stage 1.0 (TID 511) in 171 ms on ip-172-23-70-80.ec2.internal (executor 2) (1/12) 2022-04-01 03:25:05 TaskSetManager: INFO: Finished task 7.0 in stage 1.0 (TID 507) in 185 ms on ip-172-23-70-80.ec2.internal (executor 2) (2/12) 2022-04-01 03:25:05 TaskSetManager: INFO: Finished task 3.0 in stage 1.0 (TID 503) in 186 ms on ip-172-23-70-80.ec2.internal (executor 2) (3/12) 2022-04-01 03:25:05 TaskSetManager: INFO: Finished task 9.0 in stage 1.0 (TID 509) in 186 ms on ip-172-23-70-80.ec2.internal (executor 2) (4/12) 2022-04-01 03:25:05 TaskSetManager: INFO: Finished task 0.0 in stage 1.0 (TID 500) in 189 ms on ip-172-23-75-58.ec2.internal (executor 1) (5/12) 2022-04-01 03:25:05 TaskSetManager: INFO: Finished task 1.0 in stage 1.0 (TID 501) in 188 ms on ip-172-23-70-80.ec2.internal (executor 2) (6/12) 2022-04-01 03:25:05 TaskSetManager: INFO: Finished task 5.0 in stage 1.0 (TID 505) in 189 ms on ip-172-23-70-80.ec2.internal (executor 2) (7/12) 2022-04-01 03:25:05 TaskSetManager: INFO: Finished task 6.0 in stage 1.0 (TID 506) in 194 ms on ip-172-23-75-58.ec2.internal (executor 1) (8/12) 2022-04-01 03:25:05 TaskSetManager: INFO: Finished task 8.0 in stage 1.0 (TID 508) in 193 ms on ip-172-23-75-58.ec2.internal (executor 1) (9/12) 2022-04-01 03:25:05 TaskSetManager: INFO: Finished task 2.0 in stage 1.0 (TID 502) in 196 ms on ip-172-23-75-58.ec2.internal (executor 1) (10/12) 2022-04-01 03:25:05 TaskSetManager: INFO: Finished task 4.0 in stage 1.0 (TID 504) in 196 ms on ip-172-23-75-58.ec2.internal (executor 1) (11/12) 2022-04-01 03:25:05 TaskSetManager: INFO: Finished task 10.0 in stage 1.0 (TID 510) in 196 ms on ip-172-23-75-58.ec2.internal (executor 1) (12/12) 2022-04-01 03:25:05 YarnScheduler: INFO: Removed TaskSet 1.0, whose tasks have all completed, from pool 2022-04-01 03:25:05 DAGScheduler: INFO: ResultStage 1 (runJob at ContextRDD.scala:228) finished in 0.214 s 2022-04-01 03:25:05 DAGScheduler: INFO: Job 1 finished: runJob at ContextRDD.scala:228, took 0.220055 s 2022-04-01 03:25:05 Hail: INFO: Ordering unsorted dataset with network shuffle 2022-04-01 03:25:05 root: INFO: Unsorted keys: CURRENT={ locus: { contig: chr1, position: 9710632 }, alleles: [2; C, CAG] }, PREV={ locus: { contig: chr1, position: 9710632 }, alleles: [2; CAG, C] } 2022-04-01 03:25:05 MemoryStore: INFO: Block broadcast_5 stored as values in memory (estimated size 1721.0 KB, free 5.6 GB) 2022-04-01 03:25:05 MemoryStore: INFO: Block broadcast_5_piece0 stored as bytes in memory (estimated size 35.6 KB, free 5.6 GB) 2022-04-01 03:25:05 BlockManagerInfo: INFO: Added broadcast_5_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 35.6 KB, free: 5.6 GB) 2022-04-01 03:25:05 SparkContext: INFO: Created broadcast 5 from broadcast at RVDPartitioner.scala:93 2022-04-01 03:25:05 root: INFO: encoder cache miss (0 hits, 2 misses, 0.000) 2022-04-01 03:25:05 root: INFO: instruction count: 6: __C34etypeEncode. 2022-04-01 03:25:05 root: INFO: instruction count: 8: __C34etypeEncode.apply 2022-04-01 03:25:05 root: INFO: instruction count: 22: __C34etypeEncode.__m35ENCODE_r_tuple_of_r_locusANDr_array_of_r_stringEND_TO_r_struct_of_r_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryEND 2022-04-01 03:25:05 root: INFO: instruction count: 26: __C34etypeEncode.__m36ENCODE_r_tuple_of_r_binaryANDr_int32END_TO_r_struct_of_r_binaryANDr_int32END 2022-04-01 03:25:05 root: INFO: instruction count: 19: __C34etypeEncode.__m37ENCODE_r_binary_TO_r_binary 2022-04-01 03:25:05 root: INFO: instruction count: 7: __C34etypeEncode.__m38ENCODE_r_int32_TO_r_int32 2022-04-01 03:25:05 root: INFO: instruction count: 57: __C34etypeEncode.__m39ENCODE_r_array_of_r_binary_TO_r_array_of_r_binary 2022-04-01 03:25:05 root: INFO: decoder cache miss (0 hits, 1 misses, 0.000 2022-04-01 03:25:05 root: INFO: instruction count: 6: __C40etypeDecode. 2022-04-01 03:25:05 root: INFO: instruction count: 8: __C40etypeDecode.apply 2022-04-01 03:25:05 root: INFO: instruction count: 25: __C40etypeDecode.__m41DECODE_r_struct_of_r_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryEND_TO_r_tuple_of_r_locusANDr_array_of_r_stringEND 2022-04-01 03:25:05 root: INFO: instruction count: 18: __C40etypeDecode.__m42read_fields_group_0 2022-04-01 03:25:05 root: INFO: instruction count: 17: __C40etypeDecode.__m43INPLACE_DECODE_r_struct_of_r_binaryANDr_int32END_TO_r_tuple_of_r_binaryANDr_int32END 2022-04-01 03:25:05 root: INFO: instruction count: 18: __C40etypeDecode.__m44read_fields_group_0 2022-04-01 03:25:05 root: INFO: instruction count: 34: __C40etypeDecode.__m45INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:05 root: INFO: instruction count: 11: __C40etypeDecode.__m46INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:25:05 root: INFO: instruction count: 58: __C40etypeDecode.__m47INPLACE_DECODE_r_array_of_r_binary_TO_r_array_of_r_binary 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- Verify : 0.050ms, total 4.837s 2022-04-01 03:25:05 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 6: (Coalesce (InsertFields (In +PCStruct{} 0) None (gencodeVersion (Str "25"))) (Die Struct{gencodeVersion:String} (Str "Internal e..."))) 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.221ms, total 4.838s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.073ms, total 4.838s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.121ms, total 4.838s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.644ms, total 4.839s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.086ms, total 4.839s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.378ms, total 4.840s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 2.539ms, total 4.840s, tagged coverage 60.0 2022-04-01 03:25:05 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 6: (Coalesce (InsertFields (In +PCStruct{} 0) None (gencodeVersion (Str "25"))) (Die Struct{gencodeVersion:String} (Str "Internal e..."))) 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- LoweringTransformation : 3.161ms, total 4.841s, tagged coverage 48.2 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR -- Verify : 0.015ms, total 4.841s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, initial IR : 3.744ms, total 4.841s, tagged coverage 42.4 2022-04-01 03:25:05 root: INFO: Timer: Time taken for InlineApplyIR -- Verify : 0.023ms, total 4.841s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for InlineApplyIR -- LoweringTransformation : 0.065ms, total 4.841s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for InlineApplyIR -- Verify : 0.027ms, total 4.841s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for InlineApplyIR : 0.474ms, total 4.842s, tagged coverage 24.2 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- Verify : 0.011ms, total 4.842s 2022-04-01 03:25:05 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 6: (Coalesce (InsertFields (In +PCStruct{} 0) None (gencodeVersion (Str "25"))) (Die Struct{gencodeVersion:String} (Str "Internal e..."))) 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.105ms, total 4.842s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.056ms, total 4.842s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.086ms, total 4.843s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.529ms, total 4.843s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.070ms, total 4.844s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.330ms, total 4.844s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 2.022ms, total 4.844s, tagged coverage 58.2 2022-04-01 03:25:05 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 6: (Coalesce (InsertFields (In +PCStruct{} 0) None (gencodeVersion (Str "25"))) (Die Struct{gencodeVersion:String} (Str "Internal e..."))) 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 2.613ms, total 4.844s, tagged coverage 45.1 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR -- Verify : 0.013ms, total 4.845s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after InlineApplyIR : 3.156ms, total 4.845s, tagged coverage 38.1 2022-04-01 03:25:05 root: INFO: Timer: Time taken for LowerArrayAggsToRunAggs -- Verify : 0.023ms, total 4.845s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for LowerArrayAggsToRunAggs -- LoweringTransformation : 0.629ms, total 4.846s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for LowerArrayAggsToRunAggs -- Verify : 0.026ms, total 4.846s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for LowerArrayAggsToRunAggs : 1.054ms, total 4.846s, tagged coverage 64.4 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.011ms, total 4.846s 2022-04-01 03:25:05 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 6: (Coalesce (InsertFields (In +PCStruct{} 0) None (gencodeVersion (Str "25"))) (Die Struct{gencodeVersion:String} (Str "Internal e..."))) 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.102ms, total 4.847s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.054ms, total 4.847s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.087ms, total 4.847s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.515ms, total 4.848s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.067ms, total 4.848s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.304ms, total 4.849s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 1.943ms, total 4.849s, tagged coverage 58.1 2022-04-01 03:25:05 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 6: (Coalesce (InsertFields (In +PCStruct{} 0) None (gencodeVersion (Str "25"))) (Die Struct{gencodeVersion:String} (Str "Internal e..."))) 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 2.535ms, total 4.849s, tagged coverage 44.6 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.019ms, total 4.849s 2022-04-01 03:25:05 root: INFO: Timer: Time taken for optimize: compileLowerer, after LowerArrayAggsToRunAggs : 2.985ms, total 4.849s, tagged coverage 38.8 2022-04-01 03:25:05 root: INFO: encoder cache miss (0 hits, 3 misses, 0.000) 2022-04-01 03:25:05 root: INFO: instruction count: 6: __C61etypeEncode. 2022-04-01 03:25:05 root: INFO: instruction count: 8: __C61etypeEncode.apply 2022-04-01 03:25:05 root: INFO: instruction count: 26: __C61etypeEncode.__m62ENCODE_r_tuple_of_r_stringANDr_stringEND_TO_r_struct_of_r_binaryANDr_binaryEND 2022-04-01 03:25:05 root: INFO: instruction count: 19: __C61etypeEncode.__m63ENCODE_r_binary_TO_r_binary 2022-04-01 03:25:05 MemoryStore: INFO: Block broadcast_6 stored as values in memory (estimated size 112.0 B, free 5.6 GB) 2022-04-01 03:25:05 MemoryStore: INFO: Block broadcast_6_piece0 stored as bytes in memory (estimated size 111.0 B, free 5.6 GB) 2022-04-01 03:25:05 BlockManagerInfo: INFO: Added broadcast_6_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 111.0 B, free: 5.6 GB) 2022-04-01 03:25:05 SparkContext: INFO: Created broadcast 6 from broadcast at SparkBackend.scala:233 2022-04-01 03:25:05 root: INFO: instruction count: 6: __C48Compiled. 2022-04-01 03:25:05 root: INFO: instruction count: 46: __C48Compiled.apply 2022-04-01 03:25:05 root: INFO: instruction count: 8: __C48Compiled.__m53addIRIntermediate 2022-04-01 03:25:05 root: INFO: instruction count: 14: __C48Compiled.setPartitionIndex 2022-04-01 03:25:05 root: INFO: instruction count: 7: __C48Compiled.addPartitionRegion 2022-04-01 03:25:05 root: INFO: instruction count: 25: __C48Compiled.__m57DECODE_r_struct_of_r_binaryANDr_binaryEND_TO_r_tuple_of_r_stringANDr_stringEND 2022-04-01 03:25:05 root: INFO: instruction count: 18: __C48Compiled.__m58read_fields_group_0 2022-04-01 03:25:05 root: INFO: instruction count: 34: __C48Compiled.__m59INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:05 root: INFO: instruction count: 50: __C48Compiled.addLiterals 2022-04-01 03:25:05 root: INFO: encoder cache miss (0 hits, 4 misses, 0.000) 2022-04-01 03:25:06 root: INFO: instruction count: 6: __C64etypeEncode. 2022-04-01 03:25:06 root: INFO: instruction count: 8: __C64etypeEncode.apply 2022-04-01 03:25:06 root: INFO: instruction count: 51: __C64etypeEncode.__m65ENCODE_r_tuple_of_r_locusANDr_array_of_r_stringANDo_tuple_of_o_stringANDo_stringANDo_stringANDo_array_of_o_tuple_of_o_stringANDo_float64ANDo_stringANDo_float64ANDo_stringANDo_stringANDo_float64ANDo_array_of_o_stringANDo_int32ANDo_stringANDo_float64ANDo_stringANDo_float64ANDo_stringANDo_float64ANDo_stringANDo_float64ANDo_stringANDo_stringANDo_float64ANDo_stringANDo_float64ANDo_stringANDo_float64ANDo_stringANDo_float64ANDo_float64ANDo_stringANDo_float64ANDo_stringANDo_float64ANDo_stringANDo_float64ANDo_stringANDo_stringANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_stringANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_stringANDo_int32ANDo_stringANDo_stringANDo_array_of_o_tuple_of_o_int32ANDo_array_of_o_stringANDo_stringANDo_int32ANDo_stringENDANDo_stringANDo_array_of_o_tuple_of_o_int32ANDo_array_of_o_stringANDo_stringANDo_stringANDo_int32ANDo_stringANDo_stringANDo_int32ANDo_float64ANDo_int32ANDo_stringENDANDo_array_of_o_tuple_of_o_int32ANDo_stringANDo_array_of_o_stringANDo_stringANDo_int32ANDo_stringANDo_stringENDANDo_stringANDo_int32ANDo_int32ANDo_array_of_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_stringANDo_stringANDo_int32ANDo_stringANDo_stringANDo_stringANDo_int32ANDo_stringANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_stringANDo_array_of_o_stringANDo_int32ANDo_array_of_o_tuple_of_o_stringANDo_stringENDANDo_stringANDo_stringANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_int32ANDo_stringANDo_float64ANDo_int32ANDo_int32ANDo_stringANDo_stringANDo_float64ANDo_int32ANDo_stringANDo_stringANDo_stringANDo_int32ANDo_stringANDo_stringENDANDo_stringENDEND_TO_r_struct_of_r_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryANDo_struct_of_o_binaryANDo_binaryANDo_binaryANDo_array_of_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64A 2022-04-01 03:25:06 root: INFO: instruction count: 26: __C64etypeEncode.__m66ENCODE_r_tuple_of_r_binaryANDr_int32END_TO_r_struct_of_r_binaryANDr_int32END 2022-04-01 03:25:06 root: INFO: instruction count: 19: __C64etypeEncode.__m67ENCODE_r_binary_TO_r_binary 2022-04-01 03:25:06 root: INFO: instruction count: 7: __C64etypeEncode.__m68ENCODE_r_int32_TO_r_int32 2022-04-01 03:25:06 root: INFO: instruction count: 57: __C64etypeEncode.__m69ENCODE_r_array_of_r_binary_TO_r_array_of_r_binary 2022-04-01 03:25:06 root: INFO: instruction count: 379: __C64etypeEncode.__m70ENCODE_o_tuple_of_o_binaryANDo_binaryANDo_binaryANDo_array_of_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_array_of_o_tuple_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryENDANDo_binaryANDo_array_of_o_tuple_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_float64ANDo_int32ANDo_binaryENDANDo_array_of_o_tuple_of_o_int32ANDo_binaryANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDANDo_binaryANDo_int32ANDo_int32ANDo_array_of_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDANDo_binaryEND_TO_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_array_of_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryAND 2022-04-01 03:25:06 root: INFO: instruction count: 19: __C64etypeEncode.__m71ENCODE_o_binary_TO_o_binary 2022-04-01 03:25:06 root: INFO: instruction count: 122: __C64etypeEncode.__m72ENCODE_o_array_of_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_array_of_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:25:06 root: INFO: instruction count: 484: __C64etypeEncode.__m73ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:25:06 root: INFO: instruction count: 7: __C64etypeEncode.__m74ENCODE_o_float64_TO_o_float64 2022-04-01 03:25:06 root: INFO: instruction count: 126: __C64etypeEncode.__m75ENCODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:25:06 root: INFO: instruction count: 7: __C64etypeEncode.__m76ENCODE_o_int32_TO_o_int32 2022-04-01 03:25:06 root: INFO: instruction count: 126: __C64etypeEncode.__m77ENCODE_o_array_of_o_int32_TO_o_array_of_o_int32 2022-04-01 03:25:06 root: INFO: instruction count: 122: __C64etypeEncode.__m78ENCODE_o_array_of_o_tuple_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryEND_TO_o_array_of_o_struct_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 123: __C64etypeEncode.__m79ENCODE_o_tuple_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryEND_TO_o_struct_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 122: __C64etypeEncode.__m80ENCODE_o_array_of_o_tuple_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_float64ANDo_int32ANDo_binaryEND_TO_o_array_of_o_struct_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_float64ANDo_int32ANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 253: __C64etypeEncode.__m81ENCODE_o_tuple_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_float64ANDo_int32ANDo_binaryEND_TO_o_struct_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_float64ANDo_int32ANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 122: __C64etypeEncode.__m82ENCODE_o_array_of_o_tuple_of_o_int32ANDo_binaryANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_array_of_o_struct_of_o_int32ANDo_binaryANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 165: __C64etypeEncode.__m83ENCODE_o_tuple_of_o_int32ANDo_binaryANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_binaryANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 122: __C64etypeEncode.__m84ENCODE_o_array_of_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_array_of_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 493: __C64etypeEncode.__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 122: __C64etypeEncode.__m86ENCODE_o_array_of_o_tuple_of_o_binaryANDo_binaryEND_TO_o_array_of_o_struct_of_o_binaryANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 60: __C64etypeEncode.__m87ENCODE_o_tuple_of_o_binaryANDo_binaryEND_TO_o_struct_of_o_binaryANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 85: __C64etypeEncode.__m73ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion0_5 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m73ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion120_125 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m73ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion114_119 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m73ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion108_113 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m73ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion102_107 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m73ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion96_101 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m73ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion90_95 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m73ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion84_89 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m73ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion78_83 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m73ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion72_77 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m73ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion66_71 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m73ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion60_65 2022-04-01 03:25:06 root: INFO: instruction count: 85: __C64etypeEncode.__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion0_5 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion138_143 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion132_137 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion126_131 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion120_125 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion114_119 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion108_113 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion102_107 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion96_101 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion90_95 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion84_89 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion78_83 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion72_77 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion66_71 2022-04-01 03:25:06 root: INFO: instruction count: 56: __C64etypeEncode.__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion60_65 2022-04-01 03:25:06 root: INFO: instruction count: 6: __C88__m73ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDSpills. 2022-04-01 03:25:06 root: INFO: instruction count: 6: __C105__m85ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDSpills. 2022-04-01 03:25:06 root: INFO: decoder cache miss (0 hits, 2 misses, 0.000 2022-04-01 03:25:06 root: INFO: instruction count: 6: __C125etypeDecode. 2022-04-01 03:25:06 root: INFO: instruction count: 8: __C125etypeDecode.apply 2022-04-01 03:25:06 root: INFO: instruction count: 38: __C125etypeDecode.__m126DECODE_r_struct_of_r_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryANDo_struct_of_o_binaryANDo_binaryANDo_binaryANDo_array_of_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_array_of_o_struct_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryENDANDo_binaryANDo_array_of_o_struct_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_float64ANDo_int32ANDo_binaryENDANDo_array_of_o_struct_of_o_int32ANDo_binaryANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDANDo_binaryANDo_int32ANDo_int32ANDo_array_of_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDANDo_binaryENDEND_TO_r_tuple_of_r_locusANDr_array_of_r_stringANDo_tuple_of_o_stringANDo_stringANDo_stringANDo_array_of_o_tuple_of_o_stringANDo_float64ANDo_stringANDo_float64ANDo_stringANDo_stringANDo_float64ANDo_array_of_o_stringANDo_int32ANDo_stringANDo_float64ANDo_stringANDo_float64ANDo_stringANDo_fl 2022-04-01 03:25:06 root: INFO: instruction count: 46: __C125etypeDecode.__m127read_fields_group_0 2022-04-01 03:25:06 root: INFO: instruction count: 17: __C125etypeDecode.__m128INPLACE_DECODE_r_struct_of_r_binaryANDr_int32END_TO_r_tuple_of_r_binaryANDr_int32END 2022-04-01 03:25:06 root: INFO: instruction count: 18: __C125etypeDecode.__m129read_fields_group_0 2022-04-01 03:25:06 root: INFO: instruction count: 34: __C125etypeDecode.__m130INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:06 root: INFO: instruction count: 11: __C125etypeDecode.__m131INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:25:06 root: INFO: instruction count: 58: __C125etypeDecode.__m132INPLACE_DECODE_r_array_of_r_binary_TO_r_array_of_r_binary 2022-04-01 03:25:06 root: INFO: instruction count: 48: __C125etypeDecode.__m133INPLACE_DECODE_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_array_of_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_array_of_o_struct_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryENDANDo_binaryANDo_array_of_o_struct_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_float64ANDo_int32ANDo_binaryENDANDo_array_of_o_struct_of_o_int32ANDo_binaryANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDANDo_binaryANDo_int32ANDo_int32ANDo_array_of_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDANDo_binaryEND_TO_o_tuple_of_o_binaryANDo_binaryANDo_binaryANDo_array_of_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64 2022-04-01 03:25:06 root: INFO: instruction count: 480: __C125etypeDecode.__m134read_fields_group_0 2022-04-01 03:25:06 root: INFO: instruction count: 34: __C125etypeDecode.__m135INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:25:06 root: INFO: instruction count: 105: __C125etypeDecode.__m136INPLACE_DECODE_o_array_of_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_array_of_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:25:06 root: INFO: instruction count: 22: __C125etypeDecode.__m137INPLACE_DECODE_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:25:06 root: INFO: instruction count: 480: __C125etypeDecode.__m138read_fields_group_0 2022-04-01 03:25:06 root: INFO: instruction count: 11: __C125etypeDecode.__m139INPLACE_DECODE_o_float64_TO_o_float64 2022-04-01 03:25:06 root: INFO: instruction count: 105: __C125etypeDecode.__m140INPLACE_DECODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:25:06 root: INFO: instruction count: 11: __C125etypeDecode.__m141INPLACE_DECODE_o_int32_TO_o_int32 2022-04-01 03:25:06 root: INFO: instruction count: 105: __C125etypeDecode.__m142INPLACE_DECODE_o_array_of_o_int32_TO_o_array_of_o_int32 2022-04-01 03:25:06 root: INFO: instruction count: 105: __C125etypeDecode.__m143INPLACE_DECODE_o_array_of_o_struct_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryEND_TO_o_array_of_o_tuple_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 30: __C125etypeDecode.__m144INPLACE_DECODE_o_struct_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryEND_TO_o_tuple_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 144: __C125etypeDecode.__m145read_fields_group_0 2022-04-01 03:25:06 root: INFO: instruction count: 105: __C125etypeDecode.__m146INPLACE_DECODE_o_array_of_o_struct_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_float64ANDo_int32ANDo_binaryEND_TO_o_array_of_o_tuple_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_float64ANDo_int32ANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 39: __C125etypeDecode.__m147INPLACE_DECODE_o_struct_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_float64ANDo_int32ANDo_binaryEND_TO_o_tuple_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_float64ANDo_int32ANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 312: __C125etypeDecode.__m148read_fields_group_0 2022-04-01 03:25:06 root: INFO: instruction count: 105: __C125etypeDecode.__m149INPLACE_DECODE_o_array_of_o_struct_of_o_int32ANDo_binaryANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_array_of_o_tuple_of_o_int32ANDo_binaryANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 30: __C125etypeDecode.__m150INPLACE_DECODE_o_struct_of_o_int32ANDo_binaryANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_tuple_of_o_int32ANDo_binaryANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 200: __C125etypeDecode.__m151read_fields_group_0 2022-04-01 03:25:06 root: INFO: instruction count: 105: __C125etypeDecode.__m152INPLACE_DECODE_o_array_of_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_array_of_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 22: __C125etypeDecode.__m153INPLACE_DECODE_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 436: __C125etypeDecode.__m154read_fields_group_0 2022-04-01 03:25:06 root: INFO: instruction count: 105: __C125etypeDecode.__m155INPLACE_DECODE_o_array_of_o_struct_of_o_binaryANDo_binaryEND_TO_o_array_of_o_tuple_of_o_binaryANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 30: __C125etypeDecode.__m156INPLACE_DECODE_o_struct_of_o_binaryANDo_binaryEND_TO_o_tuple_of_o_binaryANDo_binaryEND 2022-04-01 03:25:06 root: INFO: instruction count: 60: __C125etypeDecode.__m157read_fields_group_0 2022-04-01 03:25:06 root: INFO: instruction count: 81: __C125etypeDecode.__m138read_fields_group_0region0_7 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m138read_fields_group_0region160_167 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m138read_fields_group_0region152_159 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m138read_fields_group_0region144_151 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m138read_fields_group_0region136_143 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m138read_fields_group_0region128_135 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m138read_fields_group_0region120_127 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m138read_fields_group_0region112_119 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m138read_fields_group_0region104_111 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m138read_fields_group_0region96_103 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m138read_fields_group_0region88_95 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m138read_fields_group_0region80_87 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m138read_fields_group_0region72_79 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m138read_fields_group_0region64_71 2022-04-01 03:25:06 root: INFO: instruction count: 81: __C125etypeDecode.__m154read_fields_group_0region0_7 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region184_191 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region176_183 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region168_175 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region160_167 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region152_159 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region144_151 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region136_143 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region128_135 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region120_127 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region112_119 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region104_111 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region96_103 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region88_95 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region80_87 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region72_79 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region64_71 2022-04-01 03:25:06 root: INFO: instruction count: 76: __C125etypeDecode.__m154read_fields_group_0region56_63 2022-04-01 03:25:06 root: INFO: instruction count: 6: __C158__m138read_fields_group_0Spills. 2022-04-01 03:25:06 root: INFO: instruction count: 6: __C178__m154read_fields_group_0Spills. 2022-04-01 03:25:06 root: INFO: encoder cache miss (0 hits, 5 misses, 0.000) 2022-04-01 03:25:06 root: INFO: instruction count: 6: __C202etypeEncode. 2022-04-01 03:25:06 root: INFO: instruction count: 8: __C202etypeEncode.apply 2022-04-01 03:25:06 root: INFO: instruction count: 6: __C202etypeEncode.__m203ENCODE_r_tuple_of_END_TO_r_struct_of_END 2022-04-01 03:25:06 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/metadata.json.gz' for reading 2022-04-01 03:25:06 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/metadata.json.gz' for reading 2022-04-01 03:25:07 BlockManagerInfo: INFO: Removed broadcast_4_piece0 on ip-172-23-79-68.ec2.internal:36757 in memory (size: 52.6 KB, free: 5.6 GB) 2022-04-01 03:25:07 BlockManagerInfo: INFO: Removed broadcast_4_piece0 on ip-172-23-70-80.ec2.internal:37501 in memory (size: 52.6 KB, free: 181.7 GB) 2022-04-01 03:25:07 BlockManagerInfo: INFO: Removed broadcast_4_piece0 on ip-172-23-75-58.ec2.internal:40133 in memory (size: 52.6 KB, free: 181.7 GB) 2022-04-01 03:25:07 BlockManagerInfo: INFO: Removed broadcast_2_piece0 on ip-172-23-75-58.ec2.internal:40133 in memory (size: 13.2 KB, free: 181.7 GB) 2022-04-01 03:25:07 BlockManagerInfo: INFO: Removed broadcast_2_piece0 on ip-172-23-70-80.ec2.internal:37501 in memory (size: 13.2 KB, free: 181.7 GB) 2022-04-01 03:25:07 BlockManagerInfo: INFO: Removed broadcast_2_piece0 on ip-172-23-79-68.ec2.internal:36757 in memory (size: 13.2 KB, free: 5.6 GB) 2022-04-01 03:25:07 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:07 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 17 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 23 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 46 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 33 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 45 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 39 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 43 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 48 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 28 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 8 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 34 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 29 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 49 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 4 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 9 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 3 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 6 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 42 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 41 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 25 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 37 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 18 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 38 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 1 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 16 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 14 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 50 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 32 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 12 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 26 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 19 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 27 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 20 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 47 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 22 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 24 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 2 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 7 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 35 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 11 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 5 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 13 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 10 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 40 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 15 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 36 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 44 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 21 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 30 2022-04-01 03:25:11 ContextCleaner: INFO: Cleaned accumulator 31 2022-04-01 03:25:12 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/metadata.json.gz' for reading 2022-04-01 03:25:12 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/metadata.json.gz' for reading 2022-04-01 03:25:12 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:12 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:17 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- Verify : 1.549ms, total 39.033ms 2022-04-01 03:25:17 root: INFO: optimize optimize: relationalLowerer, initial IR: before: IR size 1891: (MatrixWrite "{\"name\":\"MatrixNativeWriter\",\"path\":\"s3://seqr-dp-build--prod/mt-hail-luigi/SEQR2_PROD/IUIS_PANELv1_20220321.mt\",\"overwrite\":true,\"stageLocally\":false,\"codecSpecJSONStr\":null,\"partitions\":null,\"partitionsTypeStr\":null}" (MatrixMapGlobals (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixAnnotateRowsTable "__uid_112" False (MatrixMapRows (MatrixMapRows (MatrixAnnotateRowsTable "__uid_111" False (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixAnnotateRowsTable "__uid_48" False (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixAnnotateRowsTable "__uid_46" False (MatrixMapRows (MatrixMapRows (MatrixAnnotateRowsTable "__uid_44" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_43" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_42" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_41" False (MatrixMapRows (MatrixMapRows (MatrixAnnotateRowsTable "__uid_38" False (MatrixMapRows (MatrixMapRows (MatrixAnnotateRowsTable "__uid_36" False (MatrixMapRows (MatrixMapRows (MatrixAnnotateRowsTable "__uid_35" False (MatrixMapRows (MatrixMapRows (MatrixAnnotateRowsTable "__uid_34" False (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixAnnotateRowsTable "__uid_31" False (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixAnnotateRowsTable "__uid_8" False (MatrixAnnotateRowsTable "__uid_7" False (MatrixAnnotateRowsTable "__uid_6" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_5" False (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixMapRows (MatrixAnnotateRowsTable "__uid_4" False (MatrixMapGlobals (MatrixKeyRowsBy (locus alleles) False (MatrixMapRows (MatrixKeyRowsBy () False (MatrixMapRows (MatrixMapRows (MatrixRead None False False "{\"files\":[\"s3://seqr-dp-data--prod/vcf/prod/IUIS_PANELv1_20220321.vcf.gz\"],\"callFields\":[\"PGT\"],\"entryFloatTypeName\":\"Float64\",\"minPartitions\":500,\"rg\":\"GRCh38\",\"contigRecoding\":{},\"arrayElementsRequired\":false,\"skipInvalidLoci\":false,\"gzAsBGZ\":true,\"forceGZ\":false,\"filterAndReplace\":{},\"partitionsJSON\":null,\"name\":\"MatrixVCFReader\"}") (InsertFields (SelectFields (locus alleles rsid qual filters info) (Ref va)) None (a_index (I32 1)))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index) (Ref va)) None (alleles_old (GetField alleles (Ref va))) (locus_old (GetField locus (Ref va)))))) (Let __uid_3 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (Ref va)) (GetField alleles (Ref va))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old) (Ref va)) None (locus (GetField locus (Ref __uid_3))) (alleles (GetField alleles (Ref __uid_3))))))) (InsertFields (SelectFields () (Ref global)) None (gencodeVersion (Str "25")))) (TableLiteral)) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old) (Ref va)) None (vep (GetField vep (GetField __uid_4 (Ref va)))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep) (Ref va)) None (aIndex (GetField a_index (Ref va))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex) (Ref va)) None (AC (ApplyIR indexArray () Int32 (GetField AC (GetField info (Ref va))) (ApplyBinaryPrimOp Subtract (GetField a_index (Ref va)) (I32 1)) (Str " File \"/h..."))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC) (Ref va)) None (AF (ApplyIR indexArray () Float64 (GetField AF (GetField info (Ref va))) (ApplyBinaryPrimOp Subtract (GetField a_index (Ref va)) (I32 1)) (Str " File \"/h..."))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF) (Ref va)) None (alt (ApplyIR indexArray () String (GetField alleles (Ref va)) (I32 1) (Str " File \"/h..."))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt) (Ref va)) None (AN (GetField AN (GetField info (Ref va)))))) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN) (Ref va)) None (cadd (GetField cadd (GetField __uid_5 (Ref va)))))) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht\",\"name\":\"TableNativeReader\"}")) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht\",\"name\":\"TableNativeReader\"}")) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd) (Ref va)) None (clinvar (MakeStruct (allele_id (GetField ALLELEID (GetField info (GetField __uid_6 (Ref va))))) (clinical_significance (Apply mkString () String (GetField CLNSIG (GetField info (GetField __uid_7 (Ref va)))) (Str ","))) (gold_stars (GetField gold_stars (GetField __uid_8 (Ref va)))))))) (Let __cse_7 (GetField vep (Ref va)) (Let __cse_2 (Literal Dict[String,Int32] ) (Let __cse_8 (ToArray (StreamMap __uid_26 (ToStream False (ArraySort __uid_24 __uid_25 (ToStream False (ToArray (StreamMap __uid_20 (ToStream False (ToArray (StreamMap __uid_17 (ToStream False (ToArray (StreamFilter __uid_16 (ToStream False (ToArray (StreamMap __uid_9 (ToStream False (GetField transcript_consequences (Ref __cse_7))) (Let __cse_1 (GetField consequence_terms (Ref __uid_9)) (InsertFields (SelectFields (biotype canonical cdna_start cdna_end codons gene_id gene_symbol hgvsc hgvsp transcript_id amino_acids lof lof_filter lof_flags lof_info polyphen_prediction protein_id protein_start sift_prediction) (Ref __uid_9)) None (consequence_terms (ToArray (StreamFilter __uid_10 (ToStream False (Ref __cse_1)) (ApplyUnaryPrimOp Bang (ApplyIR contains () Boolean (ToSet (ToStream False (Literal Array[String] ))) (Ref __uid_10)))))) (domains (ToArray (StreamMap __uid_11 (ToStream False (GetField domains (Ref __uid_9))) (Apply concat () String (Apply concat () String (GetField db (Ref __uid_11)) (Str ":")) (GetField name (Ref __uid_11)))))) (major_consequence (If (ApplyComparisonOp GT (ArrayLen (CastToArray (Ref __cse_1))) (I32 0)) (ApplyIR indexArray () String (ToArray (StreamMap __uid_15 (ToStream False (ArraySort __uid_13 __uid_14 (ToStream False (ToArray (StreamMap __uid_12 (ToStream False (GetField consequence_terms (Ref __uid_9))) (MakeTuple (0 1) (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (Ref __uid_12)) (Ref __uid_12))))) (If (IsNA (GetTupleElement 0 (Ref __uid_13))) (False) (If (IsNA (GetTupleElement 0 (Ref __uid_14))) (True) (If (False) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __uid_14)) (GetTupleElement 0 (Ref __uid_13))) (I32 0)) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __uid_13)) (GetTupleElement 0 (Ref __uid_14))) (I32 0))))))) (GetTupleElement 1 (Ref __uid_15)))) (I32 0) (Str " File \"/h...")) (NA String)))))))) (ApplyComparisonOp GT (ArrayLen (CastToArray (GetField consequence_terms (Ref __uid_16)))) (I32 0))))) (Let __cse_5 (GetField major_consequence (Ref __uid_17)) (InsertFields (Ref __uid_17) None (category (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Ref __cse_2) (Ref __cse_5)) (ApplyIR get () Int32 (Ref __cse_2) (Str "frameshift..."))) (Str "lof") (Let __cse_3 (Literal Dict[String,Int32] ) (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Ref __cse_3) (GetField major_consequence (Ref __uid_17))) (ApplyIR get () Int32 (Ref __cse_3) (Str "missense_v..."))) (Str "missense") (Let __cse_4 (Literal Dict[String,Int32] ) (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Ref __cse_4) (GetField major_consequence (Ref __uid_17))) (ApplyIR get () Int32 (Ref __cse_4) (Str "synonymous..."))) (Str "synonymous") (Str "other"))))))) (hgvs (If (ApplySpecial lor () Boolean (IsNA (GetField hgvsp (Ref __uid_17))) (ApplyIR contains () Boolean (ToSet (ToStream False (Literal Array[String] ))) (Ref __cse_5))) (ApplyIR indexArray () String (Apply split () Array[String] (GetField hgvsc (Ref __uid_17)) (Str ":")) (I32 -1) (Str " File \"/h...")) (Let __cse_6 (GetField hgvsp (Ref __uid_17)) (If (ApplySpecial lor () Boolean (Apply contains () Boolean (Ref __cse_6) (Str "=")) (Apply contains () Boolean (Ref __cse_6) (Str "%3D"))) (Let __uid_19 (Apply mkString () String (ToArray (StreamMap __uid_18 (ToStream False (Apply split () Array[String] (GetField amino_acids (Ref __uid_17)) (Str ""))) (ApplyIR get () String (Literal Dict[String,String] ) (Ref __uid_18)))) (Str "")) (Apply concat () String (Apply concat () String (Apply concat () String (Str "p.") (Ref __uid_19)) (Apply str () String (GetField protein_start (Ref __uid_17)))) (Ref __uid_19))) (ApplyIR indexArray () String (Apply split () Array[String] (GetField hgvsp (Ref __uid_17)) (Str ":")) (I32 -1) (Str " File \"/h...")))))) (major_consequence_rank (ApplyIR get () Int32 (Ref __cse_2) (Ref __cse_5)))))))) (MakeTuple (0 1) (Let __uid_23 (ApplyComparisonOp EQ (Coalesce (GetField canonical (Ref __uid_20)) (I32 0)) (I32 1)) (Let __uid_22 (ApplyIR contains () Boolean (ToSet (ToStream False (GetField consequence_terms (Ref __uid_20)))) (GetField most_severe_consequence (Ref __cse_7))) (Let __uid_21 (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __uid_20)) (Str "")) (Str "protein_co...")) (If (Ref __uid_21) (If (Ref __uid_22) (If (Ref __uid_23) (I32 1) (I32 2)) (If (Ref __uid_23) (I32 3) (I32 4))) (If (Ref __uid_22) (If (Ref __uid_23) (I32 5) (I32 6)) (If (Ref __uid_23) (I32 7) (I32 8))))))) (Ref __uid_20))))) (If (IsNA (GetTupleElement 0 (Ref __uid_24))) (False) (If (IsNA (GetTupleElement 0 (Ref __uid_25))) (True) (If (False) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __uid_25)) (GetTupleElement 0 (Ref __uid_24))) (I32 0)) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __uid_24)) (GetTupleElement 0 (Ref __uid_25))) (I32 0))))))) (GetTupleElement 1 (Ref __uid_26)))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar) (Ref va)) None (sortedTranscriptConsequences (ToArray (StreamMap __uid_28 (ToStream False (ToArray (StreamMap __uid_27 (ToStream False (ToArray (StreamRange False (I32 0) (ArrayLen (CastToArray (Ref __cse_8))) (I32 1)))) (MakeTuple (0 1) (ApplyBinaryPrimOp Add (Ref __uid_27) (I32 0)) (ApplyIR indexArray () Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32} (Ref __cse_8) (Ref __uid_27) (Str " File \"/h...")))))) (InsertFields (GetTupleElement 1 (Ref __uid_28)) None (transcript_rank (GetTupleElement 0 (Ref __uid_28)))))))))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences) (Ref va)) None (codingGeneIds (ToSet (ToStream False (ToArray (StreamMap __uid_30 (ToStream False (ToArray (StreamFilter __uid_29 (ToStream False (GetField sortedTranscriptConsequences (Ref va))) (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __uid_29)) (Str "")) (Str "protein_co..."))))) (GetField gene_id (Ref __uid_30))))))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds) (Ref va)) None (contig (Apply replace () String (Apply contig () String (GetField locus (Ref va))) (Str "^chr") (Str ""))))) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig) (Ref va)) None (dbnsfp (GetField dbnsfp (GetField __uid_31 (Ref va)))))) (Let __cse_9 (GetField locus (Ref va)) (Let __cse_10 (GetField alleles (Ref va)) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp) (Ref va)) None (docId (ApplyIR slice () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __cse_9)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __cse_9)))) (Str "-")) (ApplyIR indexArray () String (Ref __cse_10) (I32 0) (Str " File \"/h..."))) (Str "-")) (ApplyIR indexArray () String (Ref __cse_10) (I32 1) (Str " File \"/h..."))) (I32 0) (I32 512))))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId) (Ref va)) None (domains (ToSet (ToStream False (ToArray (StreamFlatMap __uid_33 (ToStream False (GetField sortedTranscriptConsequences (Ref va))) (ToStream False (GetField domains (Ref __uid_33)))))))))) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains) (Ref va)) None (eigen (GetField eigen (GetField __uid_34 (Ref va)))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen) (Ref va)) None (end (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (Apply position () Int32 (GetField locus (Ref va))) (Apply length () Int32 (ApplyIR indexArray () String (GetField alleles (Ref va)) (I32 0) (Str " File \"/h...")))) (I32 1))))) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end) (Ref va)) None (exac (GetField exac (GetField __uid_35 (Ref va)))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac) (Ref va)) None (filters (GetField filters (Ref va))))) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac) (Ref va)) None (g1k (GetField g1k (GetField __uid_36 (Ref va)))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k) (Ref va)) None (geneIds (ToSet (ToStream False (ToArray (StreamMap __uid_37 (ToStream False (GetField sortedTranscriptConsequences (Ref va))) (GetField gene_id (Ref __uid_37))))))))) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds) (Ref va)) None (geno2mp (GetField geno2mp (GetField __uid_38 (Ref va)))))) (AggLet __cse_11 False (ApplyUnaryPrimOp Bang (IsNA (GetField GT (Ref g)))) (AggLet __cse_12 False (GetField AD (Ref g)) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp) (Ref va)) None (genotypes (ApplyAggOp Collect () ( (MakeStruct (num_alt (If (Ref __cse_11) (Apply nNonRefAlleles () Int32 (GetField GT (Ref g))) (I32 -1))) (gq (If (Ref __cse_11) (GetField GQ (Ref g)) (NA Int32))) (ab (Let __uid_40 (ApplyIR sum () Int32 (ToArray (StreamFilter __uid_39 (ToStream False (Ref __cse_12)) (ApplyUnaryPrimOp Bang (IsNA (Ref __uid_39)))))) (If (ApplySpecial land () Boolean (ApplySpecial land () Boolean (Ref __cse_11) (ApplyComparisonOp NEQ (Ref __uid_40) (I32 0))) (ApplyComparisonOp GT (ArrayLen (CastToArray (Ref __cse_12))) (I32 1))) (ApplyIR toFloat64 () Float64 (ApplyBinaryPrimOp FloatingPointDivide (ApplyIR indexArray () Int32 (GetField AD (Ref g)) (I32 1) (Str " File \"/h...")) (Ref __uid_40))) (NA Float64)))) (dp (If (Ref __cse_11) (ApplyIR toFloat64 () Float64 (ApplySpecial min_ignore_missing () Int32 (GetField DP (Ref g)) (I32 32000))) (NA Float64))) (ad (If (Ref __cse_11) (Apply format () String (Str "%s") (MakeTuple (0) (GetField AD (Ref g)))) (NA String))) (pl (If (Ref __cse_11) (Apply format () String (Str "%s") (MakeTuple (0) (GetField PL (Ref g)))) (NA String))) (sample_id (GetField s (Ref sa))))))))))) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes) (Ref va)) None (gnomad_exome_coverage (GetField gnomad_exome_coverage (GetField __uid_41 (Ref va)))))) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage) (Ref va)) None (gnomad_exomes (GetField gnomad_exomes (GetField __uid_42 (Ref va)))))) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes) (Ref va)) None (gnomad_genome_coverage (GetField gnomad_genome_coverage (GetField __uid_43 (Ref va)))))) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage) (Ref va)) None (gnomad_genomes (GetField gnomad_genomes (GetField __uid_44 (Ref va)))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes) (Ref va)) None (mainTranscript (If (ApplyComparisonOp EQ (ArrayLen (CastToArray (GetField sortedTranscriptConsequences (Ref va)))) (I32 0)) (MakeStruct (biotype (NA String)) (canonical (NA Int32)) (category (NA String)) (cdna_start (NA Int32)) (cdna_end (NA Int32)) (codons (NA String)) (gene_id (NA String)) (gene_symbol (NA String)) (hgvs (NA String)) (hgvsc (NA String)) (major_consequence (NA String)) (major_consequence_rank (NA Int32)) (transcript_id (NA String)) (amino_acids (NA String)) (domains (NA String)) (hgvsp (NA String)) (lof (NA String)) (lof_flags (NA String)) (lof_filter (NA String)) (lof_info (NA String)) (polyphen_prediction (NA String)) (protein_id (NA String)) (sift_prediction (NA String))) (Let __uid_45 (ApplyIR indexArray () Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32} (GetField sortedTranscriptConsequences (Ref va)) (I32 0) (Str " File \"/h...")) (SelectFields (biotype canonical category cdna_start cdna_end codons gene_id gene_symbol hgvs hgvsc major_consequence major_consequence_rank transcript_id amino_acids domains hgvsp lof lof_flags lof_filter lof_info polyphen_prediction protein_id sift_prediction) (InsertFields (Ref __uid_45) None (domains (Apply mkString () String (ToSet (ToStream False (GetField domains (Ref __uid_45)))) (Str ",")))))))))) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript) (Ref va)) None (mpc (GetField mpc (GetField __uid_46 (Ref va)))))) (Let __cse_14 (GetField alleles_old (Ref va)) (Let __cse_13 (GetField locus_old (Ref va)) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc) (Ref va)) None (originalAltAlleles (ToArray (StreamMap __uid_47 (ToStream False (ApplyIR sliceRight () Array[String] (Ref __cse_14) (I32 1))) (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply contig () String (Ref __cse_13)) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __cse_13)))) (Str "-")) (ApplyIR indexArray () String (Ref __cse_14) (I32 0) (Str " File \"/h..."))) (Str "-")) (Ref __uid_47))))))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles) (Ref va)) None (pos (Apply position () Int32 (GetField locus (Ref va)))))) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos) (Ref va)) None (primate_ai (GetField primate_ai (GetField __uid_48 (Ref va)))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai) (Ref va)) None (ref (ApplyIR indexArray () String (GetField alleles (Ref va)) (I32 0) (Str " File \"/h..."))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref) (Ref va)) None (rsid (GetField rsid (Ref va))))) (Let __cse_16 (GetField genotypes (Ref va)) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref) (Ref va)) None (samples_ab (MakeStruct (0_to_5 (ToSet (ToStream False (ToArray (StreamMap __uid_50 (ToStream False (ToArray (StreamFilter __uid_49 (ToStream False (Ref __cse_16)) (Let __cse_15 (GetField ab (Ref __uid_49)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __uid_49)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __cse_15) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 0)))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __cse_15) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 5)))))))) (GetField sample_id (Ref __uid_50))))))) (5_to_10 (ToSet (ToStream False (ToArray (StreamMap __uid_52 (ToStream False (ToArray (StreamFilter __uid_51 (ToStream False (Ref __cse_16)) (Let __cse_17 (GetField ab (Ref __uid_51)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __uid_51)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __cse_17) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 5)))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __cse_17) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 10)))))))) (GetField sample_id (Ref __uid_52))))))) (10_to_15 (ToSet (ToStream False (ToArray (StreamMap __uid_54 (ToStream False (ToArray (StreamFilter __uid_53 (ToStream False (Ref __cse_16)) (Let __cse_18 (GetField ab (Ref __uid_53)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __uid_53)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __cse_18) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 10)))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __cse_18) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 15)))))))) (GetField sample_id (Ref __uid_54))))))) (15_to_20 (ToSet (ToStream False (ToArray (StreamMap __uid_56 (ToStream False (ToArray (StreamFilter __uid_55 (ToStream False (Ref __cse_16)) (Let __cse_19 (GetField ab (Ref __uid_55)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __uid_55)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __cse_19) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 15)))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __cse_19) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 20)))))))) (GetField sample_id (Ref __uid_56))))))) (20_to_25 (ToSet (ToStream False (ToArray (StreamMap __uid_58 (ToStream False (ToArray (StreamFilter __uid_57 (ToStream False (Ref __cse_16)) (Let __cse_20 (GetField ab (Ref __uid_57)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __uid_57)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __cse_20) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 20)))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __cse_20) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 25)))))))) (GetField sample_id (Ref __uid_58))))))) (25_to_30 (ToSet (ToStream False (ToArray (StreamMap __uid_60 (ToStream False (ToArray (StreamFilter __uid_59 (ToStream False (Ref __cse_16)) (Let __cse_21 (GetField ab (Ref __uid_59)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __uid_59)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __cse_21) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 25)))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __cse_21) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 30)))))))) (GetField sample_id (Ref __uid_60))))))) (30_to_35 (ToSet (ToStream False (ToArray (StreamMap __uid_62 (ToStream False (ToArray (StreamFilter __uid_61 (ToStream False (Ref __cse_16)) (Let __cse_22 (GetField ab (Ref __uid_61)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __uid_61)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __cse_22) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 30)))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __cse_22) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 35)))))))) (GetField sample_id (Ref __uid_62))))))) (35_to_40 (ToSet (ToStream False (ToArray (StreamMap __uid_64 (ToStream False (ToArray (StreamFilter __uid_63 (ToStream False (Ref __cse_16)) (Let __cse_23 (GetField ab (Ref __uid_63)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __uid_63)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __cse_23) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 35)))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __cse_23) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 40)))))))) (GetField sample_id (Ref __uid_64))))))) (40_to_45 (ToSet (ToStream False (ToArray (StreamMap __uid_66 (ToStream False (ToArray (StreamFilter __uid_65 (ToStream False (Ref __cse_16)) (Let __cse_24 (GetField ab (Ref __uid_65)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __uid_65)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __cse_24) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 40)))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __cse_24) (ApplyIR toFloat64 () Float64 (I32 100))) (ApplyIR toFloat64 () Float64 (I32 45)))))))) (GetField sample_id (Ref __uid_66)))))))))))) (Let __cse_26 (GetField genotypes (Ref va)) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab) (Ref va)) None (samples_gq (MakeStruct (0_to_5 (ToSet (ToStream False (ToArray (StreamMap __uid_68 (ToStream False (ToArray (StreamFilter __uid_67 (ToStream False (Ref __cse_26)) (Let __cse_25 (GetField gq (Ref __uid_67)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_25) (I32 0)) (ApplyComparisonOp LT (Ref __cse_25) (I32 5))))))) (GetField sample_id (Ref __uid_68))))))) (5_to_10 (ToSet (ToStream False (ToArray (StreamMap __uid_70 (ToStream False (ToArray (StreamFilter __uid_69 (ToStream False (Ref __cse_26)) (Let __cse_27 (GetField gq (Ref __uid_69)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_27) (I32 5)) (ApplyComparisonOp LT (Ref __cse_27) (I32 10))))))) (GetField sample_id (Ref __uid_70))))))) (10_to_15 (ToSet (ToStream False (ToArray (StreamMap __uid_72 (ToStream False (ToArray (StreamFilter __uid_71 (ToStream False (Ref __cse_26)) (Let __cse_28 (GetField gq (Ref __uid_71)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_28) (I32 10)) (ApplyComparisonOp LT (Ref __cse_28) (I32 15))))))) (GetField sample_id (Ref __uid_72))))))) (15_to_20 (ToSet (ToStream False (ToArray (StreamMap __uid_74 (ToStream False (ToArray (StreamFilter __uid_73 (ToStream False (Ref __cse_26)) (Let __cse_29 (GetField gq (Ref __uid_73)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_29) (I32 15)) (ApplyComparisonOp LT (Ref __cse_29) (I32 20))))))) (GetField sample_id (Ref __uid_74))))))) (20_to_25 (ToSet (ToStream False (ToArray (StreamMap __uid_76 (ToStream False (ToArray (StreamFilter __uid_75 (ToStream False (Ref __cse_26)) (Let __cse_30 (GetField gq (Ref __uid_75)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_30) (I32 20)) (ApplyComparisonOp LT (Ref __cse_30) (I32 25))))))) (GetField sample_id (Ref __uid_76))))))) (25_to_30 (ToSet (ToStream False (ToArray (StreamMap __uid_78 (ToStream False (ToArray (StreamFilter __uid_77 (ToStream False (Ref __cse_26)) (Let __cse_31 (GetField gq (Ref __uid_77)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_31) (I32 25)) (ApplyComparisonOp LT (Ref __cse_31) (I32 30))))))) (GetField sample_id (Ref __uid_78))))))) (30_to_35 (ToSet (ToStream False (ToArray (StreamMap __uid_80 (ToStream False (ToArray (StreamFilter __uid_79 (ToStream False (Ref __cse_26)) (Let __cse_32 (GetField gq (Ref __uid_79)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_32) (I32 30)) (ApplyComparisonOp LT (Ref __cse_32) (I32 35))))))) (GetField sample_id (Ref __uid_80))))))) (35_to_40 (ToSet (ToStream False (ToArray (StreamMap __uid_82 (ToStream False (ToArray (StreamFilter __uid_81 (ToStream False (Ref __cse_26)) (Let __cse_33 (GetField gq (Ref __uid_81)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_33) (I32 35)) (ApplyComparisonOp LT (Ref __cse_33) (I32 40))))))) (GetField sample_id (Ref __uid_82))))))) (40_to_45 (ToSet (ToStream False (ToArray (StreamMap __uid_84 (ToStream False (ToArray (StreamFilter __uid_83 (ToStream False (Ref __cse_26)) (Let __cse_34 (GetField gq (Ref __uid_83)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_34) (I32 40)) (ApplyComparisonOp LT (Ref __cse_34) (I32 45))))))) (GetField sample_id (Ref __uid_84))))))) (45_to_50 (ToSet (ToStream False (ToArray (StreamMap __uid_86 (ToStream False (ToArray (StreamFilter __uid_85 (ToStream False (Ref __cse_26)) (Let __cse_35 (GetField gq (Ref __uid_85)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_35) (I32 45)) (ApplyComparisonOp LT (Ref __cse_35) (I32 50))))))) (GetField sample_id (Ref __uid_86))))))) (50_to_55 (ToSet (ToStream False (ToArray (StreamMap __uid_88 (ToStream False (ToArray (StreamFilter __uid_87 (ToStream False (Ref __cse_26)) (Let __cse_36 (GetField gq (Ref __uid_87)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_36) (I32 50)) (ApplyComparisonOp LT (Ref __cse_36) (I32 55))))))) (GetField sample_id (Ref __uid_88))))))) (55_to_60 (ToSet (ToStream False (ToArray (StreamMap __uid_90 (ToStream False (ToArray (StreamFilter __uid_89 (ToStream False (Ref __cse_26)) (Let __cse_37 (GetField gq (Ref __uid_89)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_37) (I32 55)) (ApplyComparisonOp LT (Ref __cse_37) (I32 60))))))) (GetField sample_id (Ref __uid_90))))))) (60_to_65 (ToSet (ToStream False (ToArray (StreamMap __uid_92 (ToStream False (ToArray (StreamFilter __uid_91 (ToStream False (Ref __cse_26)) (Let __cse_38 (GetField gq (Ref __uid_91)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_38) (I32 60)) (ApplyComparisonOp LT (Ref __cse_38) (I32 65))))))) (GetField sample_id (Ref __uid_92))))))) (65_to_70 (ToSet (ToStream False (ToArray (StreamMap __uid_94 (ToStream False (ToArray (StreamFilter __uid_93 (ToStream False (Ref __cse_26)) (Let __cse_39 (GetField gq (Ref __uid_93)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_39) (I32 65)) (ApplyComparisonOp LT (Ref __cse_39) (I32 70))))))) (GetField sample_id (Ref __uid_94))))))) (70_to_75 (ToSet (ToStream False (ToArray (StreamMap __uid_96 (ToStream False (ToArray (StreamFilter __uid_95 (ToStream False (Ref __cse_26)) (Let __cse_40 (GetField gq (Ref __uid_95)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_40) (I32 70)) (ApplyComparisonOp LT (Ref __cse_40) (I32 75))))))) (GetField sample_id (Ref __uid_96))))))) (75_to_80 (ToSet (ToStream False (ToArray (StreamMap __uid_98 (ToStream False (ToArray (StreamFilter __uid_97 (ToStream False (Ref __cse_26)) (Let __cse_41 (GetField gq (Ref __uid_97)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_41) (I32 75)) (ApplyComparisonOp LT (Ref __cse_41) (I32 80))))))) (GetField sample_id (Ref __uid_98))))))) (80_to_85 (ToSet (ToStream False (ToArray (StreamMap __uid_100 (ToStream False (ToArray (StreamFilter __uid_99 (ToStream False (Ref __cse_26)) (Let __cse_42 (GetField gq (Ref __uid_99)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_42) (I32 80)) (ApplyComparisonOp LT (Ref __cse_42) (I32 85))))))) (GetField sample_id (Ref __uid_100))))))) (85_to_90 (ToSet (ToStream False (ToArray (StreamMap __uid_102 (ToStream False (ToArray (StreamFilter __uid_101 (ToStream False (Ref __cse_26)) (Let __cse_43 (GetField gq (Ref __uid_101)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_43) (I32 85)) (ApplyComparisonOp LT (Ref __cse_43) (I32 90))))))) (GetField sample_id (Ref __uid_102))))))) (90_to_95 (ToSet (ToStream False (ToArray (StreamMap __uid_104 (ToStream False (ToArray (StreamFilter __uid_103 (ToStream False (Ref __cse_26)) (Let __cse_44 (GetField gq (Ref __uid_103)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __cse_44) (I32 90)) (ApplyComparisonOp LT (Ref __cse_44) (I32 95))))))) (GetField sample_id (Ref __uid_104)))))))))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq) (Ref va)) None (samples_no_call (ToSet (ToStream False (ToArray (StreamMap __uid_106 (ToStream False (ToArray (StreamFilter __uid_105 (ToStream False (GetField genotypes (Ref va))) (ApplyComparisonOp EQ (GetField num_alt (Ref __uid_105)) (I32 -1))))) (GetField sample_id (Ref __uid_106))))))))) (Let __cse_45 (GetField genotypes (Ref va)) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call) (Ref va)) None (samples_num_alt (MakeStruct (1 (ToSet (ToStream False (ToArray (StreamMap __uid_108 (ToStream False (ToArray (StreamFilter __uid_107 (ToStream False (Ref __cse_45)) (ApplyComparisonOp EQ (GetField num_alt (Ref __uid_107)) (I32 1))))) (GetField sample_id (Ref __uid_108))))))) (2 (ToSet (ToStream False (ToArray (StreamMap __uid_110 (ToStream False (ToArray (StreamFilter __uid_109 (ToStream False (Ref __cse_45)) (ApplyComparisonOp EQ (GetField num_alt (Ref __uid_109)) (I32 2))))) (GetField sample_id (Ref __uid_110)))))))))))) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt) (Ref va)) None (splice_ai (GetField splice_ai (GetField __uid_111 (Ref va)))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai) (Ref va)) None (start (Apply position () Int32 (GetField locus (Ref va)))))) (TableRead None False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start) (Ref va)) None (topmed (GetField topmed (GetField __uid_112 (Ref va)))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start topmed) (Ref va)) None (transcriptConsequenceTerms (ToSet (ToStream False (ToArray (StreamFlatMap __uid_114 (ToStream False (GetField sortedTranscriptConsequences (Ref va))) (ToStream False (GetField consequence_terms (Ref __uid_114)))))))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start topmed transcriptConsequenceTerms) (Ref va)) None (transcriptIds (ToSet (ToStream False (ToArray (StreamMap __uid_115 (ToStream False (GetField sortedTranscriptConsequences (Ref va))) (GetField transcript_id (Ref __uid_115))))))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start topmed transcriptConsequenceTerms transcriptIds) (Ref va)) None (utrVariantAnnotation (ToArray (StreamMap __uid_117 (ToStream False (ToArray (StreamFilter __uid_116 (ToStream False (GetField transcript_consequences (GetField vep (Ref va)))) (ApplyIR contains () Boolean (GetField consequence_terms (Ref __uid_116)) (Str "5_prime_UT..."))))) (MakeStruct (existing_inframe_oorfs (GetField existing_inframe_oorfs (Ref __uid_117))) (existing_outofframe_oorfs (GetField existing_outofframe_oorfs (Ref __uid_117))) (existing_uorfs (GetField existing_uorfs (Ref __uid_117))) (five_prime_utr_variant_consequence (GetField five_prime_utr_variant_consequence (Ref __uid_117))) (five_prime_utr_variant_annotation (GetField five_prime_utr_variant_annotation (Ref __uid_117))))))))) (Let __cse_46 (GetField locus (Ref va)) (Let __cse_47 (GetField alleles (Ref va)) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start topmed transcriptConsequenceTerms transcriptIds utrVariantAnnotation) (Ref va)) None (variantId (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __cse_46)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __cse_46)))) (Str "-")) (ApplyIR indexArray () String (Ref __cse_47) (I32 0) (Str " File \"/h..."))) (Str "-")) (ApplyIR indexArray () String (Ref __cse_47) (I32 1) (Str " File \"/h...")))))))) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start topmed transcriptConsequenceTerms transcriptIds utrVariantAnnotation variantId) (Ref va)) None (vep (GetField vep (Ref va))))) (Let __cse_48 (GetField locus (Ref va)) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start topmed transcriptConsequenceTerms transcriptIds utrVariantAnnotation variantId) (Ref va)) None (xpos (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (ApplyIR toInt64 () Int64 (Let __uid_118 (Apply replace () String (Apply contig () String (Ref __cse_48)) (Str "^chr") (Str "")) (If (ApplyComparisonOp EQ (Ref __uid_118) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __uid_118) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __uid_118) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __uid_118))))))) (ApplyIR toInt64 () Int64 (I32 1000000000))) (ApplyIR toInt64 () Int64 (Apply position () Int32 (Ref __cse_48)))))))) (Let __cse_49 (GetField locus (Ref va)) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start topmed transcriptConsequenceTerms transcriptIds utrVariantAnnotation variantId xpos) (Ref va)) None (xstart (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (ApplyIR toInt64 () Int64 (Let __uid_119 (Apply replace () String (Apply contig () String (Ref __cse_49)) (Str "^chr") (Str "")) (If (ApplyComparisonOp EQ (Ref __uid_119) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __uid_119) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __uid_119) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __uid_119))))))) (ApplyIR toInt64 () Int64 (I32 1000000000))) (ApplyIR toInt64 () Int64 (Apply position () Int32 (Ref __cse_49)))))))) (Let __cse_50 (GetField locus (Ref va)) (InsertFields (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start topmed transcriptConsequenceTerms transcriptIds utrVariantAnnotation variantId xpos xstart) (Ref va)) None (xstop (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (ApplyIR toInt64 () Int64 (Let __uid_120 (Apply replace () String (Apply contig () String (Ref __cse_50)) (Str "^chr") (Str "")) (If (ApplyComparisonOp EQ (Ref __uid_120) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __uid_120) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __uid_120) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __uid_120))))))) (ApplyIR toInt64 () Int64 (I32 1000000000))) (ApplyIR toInt64 () Int64 (Apply position () Int32 (Ref __cse_50)))) (ApplyIR toInt64 () Int64 (Apply length () Int32 (ApplyIR indexArray () String (GetField alleles (Ref va)) (I32 0) (Str " File \"/h..."))))) (ApplyIR toInt64 () Int64 (I32 1))))))) (InsertFields (SelectFields (locus alleles aIndex AC AF alt AN cadd clinvar codingGeneIds contig dbnsfp docId domains eigen end exac filters g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref rsid samples_ab samples_gq samples_no_call samples_num_alt sortedTranscriptConsequences splice_ai start topmed transcriptConsequenceTerms transcriptIds utrVariantAnnotation variantId vep xpos xstart xstop) (SelectFields (locus alleles rsid qual filters info a_index alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start topmed transcriptConsequenceTerms transcriptIds utrVariantAnnotation variantId xpos xstart xstop) (Ref va))) None)) (InsertFields (SelectFields (gencodeVersion) (Ref global)) None (sourceFilePath (Str "s3://seqr-...")) (genomeVersion (Str "38")) (sampleType (Str "WGS")) (hail_version (Str "0.2.57"))))) 2022-04-01 03:25:17 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 23.394ms, total 136.043ms 2022-04-01 03:25:17 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 27.604ms, total 163.865ms 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 608.853ms, total 772.865ms 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 70.614ms, total 843.679ms 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 6.155ms, total 850.028ms 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 220.734ms, total 1.071s 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 14.670ms, total 1.086s 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 10.341ms, total 1.096s 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 16.998ms, total 1.114s 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 58.908ms, total 1.173s 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 4.554ms, total 1.177s 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 170.752ms, total 1.348s 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 8.203ms, total 1.357s 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 12.022ms, total 1.369s 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 12.841ms, total 1.382s 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 58.086ms, total 1.440s 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 4.239ms, total 1.445s 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 145.954ms, total 1.591s 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation -- Optimize : 1.479s, total 1.591s, tagged coverage 99.8 2022-04-01 03:25:18 root: INFO: optimize optimize: relationalLowerer, initial IR: after: IR size 1529: (MatrixWrite "{\"name\":\"MatrixNativeWriter\",\"path\":\"s3://seqr-dp-build--prod/mt-hail-luigi/SEQR2_PROD/IUIS_PANELv1_20220321.mt\",\"overwrite\":true,\"stageLocally\":false,\"codecSpecJSONStr\":null,\"partitions\":null,\"partitionsTypeStr\":null}" (MatrixMapGlobals (MatrixMapRows (MatrixAnnotateRowsTable "__uid_112" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_111" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_48" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_46" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_44" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_43" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_42" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_41" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_38" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_36" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_35" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_34" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_31" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_8" False (MatrixAnnotateRowsTable "__uid_7" False (MatrixAnnotateRowsTable "__uid_6" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_5" False (MatrixMapRows (MatrixAnnotateRowsTable "__uid_4" False (MatrixMapGlobals (MatrixKeyRowsBy (locus alleles) False (MatrixMapRows (MatrixKeyRowsBy () False (MatrixMapRows (MatrixRead Matrix{global:Struct{},col_key:[s],col:Struct{s:String},row_key:[[locus,alleles]],row:Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32}},entry:Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}} False False "{\"files\":[\"s3://seqr-dp-data--prod/vcf/prod/IUIS_PANELv1_20220321.vcf.gz\"],\"callFields\":[\"PGT\"],\"entryFloatTypeName\":\"Float64\",\"minPartitions\":500,\"rg\":\"GRCh38\",\"contigRecoding\":{},\"arrayElementsRequired\":false,\"skipInvalidLoci\":false,\"gzAsBGZ\":true,\"forceGZ\":false,\"filterAndReplace\":{},\"partitionsJSON\":null,\"name\":\"MatrixVCFReader\"}") (InsertFields (Ref va) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old") (a_index (I32 1)) (alleles_old (GetField alleles (Ref va))) (locus_old (GetField locus (Ref va)))))) (Let __iruid_2515 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (Ref va)) (GetField alleles (Ref va))) (InsertFields (Ref va) None (locus (GetField locus (Ref __iruid_2515))) (alleles (GetField alleles (Ref __iruid_2515))))))) (InsertFields (Ref global) None (gencodeVersion (Str "25")))) (TableLiteral)) (Let __iruid_2516 (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (Ref va)) (InsertFields (Ref __iruid_2516) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN") (vep (GetField vep (GetField __uid_4 (Ref va)))) (aIndex (GetField a_index (Ref __iruid_2516))) (AC (ApplyIR indexArray () Int32 (GetField AC (GetField info (Ref __iruid_2516))) (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_2516)) (I32 1)) (Str " File \"/h..."))) (AF (ApplyIR indexArray () Float64 (GetField AF (GetField info (Ref __iruid_2516))) (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_2516)) (I32 1)) (Str " File \"/h..."))) (alt (ApplyIR indexArray () String (GetField alleles (Ref __iruid_2516)) (I32 1) (Str " File \"/h..."))) (AN (GetField AN (GetField info (Ref __iruid_2516))))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],cadd:Struct{PHRED:Float32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN) (Ref va)) None (cadd (GetField cadd (GetField __uid_5 (Ref va)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],info:Struct{ALLELEID:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht\",\"name\":\"TableNativeReader\"}")) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],info:Struct{CLNSIG:Array[String]}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht\",\"name\":\"TableNativeReader\"}")) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],gold_stars:Int32}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht\",\"name\":\"TableNativeReader\"}")) (Let __iruid_2526 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd) (Ref va)) (Let __iruid_2527 (GetField vep (Ref __iruid_2526)) (Let __iruid_2528 (ToArray (StreamMap __iruid_2529 (ToStream False (ArraySort __iruid_2530 __iruid_2531 (StreamMap __iruid_2532 (StreamFilter __iruid_2533 (StreamMap __iruid_2534 (ToStream False (GetField transcript_consequences (Ref __iruid_2527))) (Let __iruid_2535 (GetField consequence_terms (Ref __iruid_2534)) (InsertFields (SelectFields (biotype canonical cdna_start cdna_end codons gene_id gene_symbol hgvsc hgvsp transcript_id amino_acids lof lof_filter lof_flags lof_info polyphen_prediction protein_id protein_start sift_prediction) (Ref __iruid_2534)) None (consequence_terms (ToArray (StreamFilter __iruid_2536 (ToStream False (Ref __iruid_2535)) (ApplyUnaryPrimOp Bang (ApplyIR contains () Boolean (ToSet (ToStream False (Literal Array[String] ))) (Ref __iruid_2536)))))) (domains (ToArray (StreamMap __iruid_2537 (ToStream False (GetField domains (Ref __iruid_2534))) (Apply concat () String (Apply concat () String (GetField db (Ref __iruid_2537)) (Str ":")) (GetField name (Ref __iruid_2537)))))) (major_consequence (If (ApplyComparisonOp GT (ArrayLen (Ref __iruid_2535)) (I32 0)) (ApplyIR indexArray () String (ToArray (StreamMap __iruid_2538 (ToStream False (ArraySort __iruid_2539 __iruid_2540 (StreamMap __iruid_2541 (ToStream False (GetField consequence_terms (Ref __iruid_2534))) (MakeTuple (0 1) (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (Ref __iruid_2541)) (Ref __iruid_2541))) (If (IsNA (GetTupleElement 0 (Ref __iruid_2539))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_2540))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_2539)) (GetTupleElement 0 (Ref __iruid_2540))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_2538)))) (I32 0) (Str " File \"/h...")) (NA String)))))) (ApplyComparisonOp GT (ArrayLen (GetField consequence_terms (Ref __iruid_2533))) (I32 0))) (Let __iruid_2542 (GetField major_consequence (Ref __iruid_2532)) (Let __iruid_2543 (InsertFields (Ref __iruid_2532) None (category (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (Ref __iruid_2542)) (I32 4)) (Str "lof") (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (GetField major_consequence (Ref __iruid_2532))) (I32 11)) (Str "missense") (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (GetField major_consequence (Ref __iruid_2532))) (I32 17)) (Str "synonymous") (Str "other"))))) (hgvs (If (ApplySpecial lor () Boolean (IsNA (GetField hgvsp (Ref __iruid_2532))) (ApplyIR contains () Boolean (ToSet (ToStream False (Literal Array[String] ))) (Ref __iruid_2542))) (ApplyIR indexArray () String (Apply split () Array[String] (GetField hgvsc (Ref __iruid_2532)) (Str ":")) (I32 -1) (Str " File \"/h...")) (Let __iruid_2544 (GetField hgvsp (Ref __iruid_2532)) (If (ApplySpecial lor () Boolean (Apply contains () Boolean (Ref __iruid_2544) (Str "=")) (Apply contains () Boolean (Ref __iruid_2544) (Str "%3D"))) (Let __iruid_2545 (Apply mkString () String (ToArray (StreamMap __iruid_2546 (ToStream False (Apply split () Array[String] (GetField amino_acids (Ref __iruid_2532)) (Str ""))) (ApplyIR get () String (Literal Dict[String,String] ) (Ref __iruid_2546)))) (Str "")) (Apply concat () String (Apply concat () String (Apply concat () String (Str "p.") (Ref __iruid_2545)) (Apply str () String (GetField protein_start (Ref __iruid_2532)))) (Ref __iruid_2545))) (ApplyIR indexArray () String (Apply split () Array[String] (GetField hgvsp (Ref __iruid_2532)) (Str ":")) (I32 -1) (Str " File \"/h...")))))) (major_consequence_rank (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (Ref __iruid_2542)))) (MakeTuple (0 1) (Let __iruid_2547 (ApplyComparisonOp EQ (Coalesce (GetField canonical (Ref __iruid_2543)) (I32 0)) (I32 1)) (Let __iruid_2548 (ApplyIR contains () Boolean (ToSet (ToStream False (GetField consequence_terms (Ref __iruid_2543)))) (GetField most_severe_consequence (Ref __iruid_2527))) (If (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_2543)) (Str "")) (Str "protein_co...")) (If (Ref __iruid_2548) (If (Ref __iruid_2547) (I32 1) (I32 2)) (If (Ref __iruid_2547) (I32 3) (I32 4))) (If (Ref __iruid_2548) (If (Ref __iruid_2547) (I32 5) (I32 6)) (If (Ref __iruid_2547) (I32 7) (I32 8)))))) (Ref __iruid_2543))))) (If (IsNA (GetTupleElement 0 (Ref __iruid_2530))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_2531))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_2530)) (GetTupleElement 0 (Ref __iruid_2531))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_2529)))) (Let __iruid_2549 (ToArray (StreamMap __iruid_2550 (StreamRange False (I32 0) (ArrayLen (Ref __iruid_2528)) (I32 1)) (Let __iruid_2551 (MakeTuple (0 1) (Ref __iruid_2550) (ApplyIR indexArray () Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32} (Ref __iruid_2528) (Ref __iruid_2550) (Str " File \"/h..."))) (InsertFields (GetTupleElement 1 (Ref __iruid_2551)) None (transcript_rank (GetTupleElement 0 (Ref __iruid_2551))))))) (InsertFields (Ref __iruid_2526) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig") (clinvar (MakeStruct (allele_id (GetField ALLELEID (GetField info (GetField __uid_6 (Ref va))))) (clinical_significance (Apply mkString () String (GetField CLNSIG (GetField info (GetField __uid_7 (Ref va)))) (Str ","))) (gold_stars (GetField gold_stars (GetField __uid_8 (Ref va)))))) (sortedTranscriptConsequences (Ref __iruid_2549)) (codingGeneIds (ToSet (StreamMap __iruid_2552 (StreamFilter __iruid_2553 (ToStream False (Ref __iruid_2549)) (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_2553)) (Str "")) (Str "protein_co..."))) (GetField gene_id (Ref __iruid_2552))))) (contig (Apply replace () String (Apply contig () String (GetField locus (Ref __iruid_2526))) (Str "^chr") (Str ""))))))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let __iruid_2554 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig) (Ref va)) (Let __iruid_2555 (GetField locus (Ref __iruid_2554)) (Let __iruid_2556 (GetField alleles (Ref __iruid_2554)) (InsertFields (Ref __iruid_2554) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains") (dbnsfp (GetField dbnsfp (GetField __uid_31 (Ref va)))) (docId (ApplyIR slice () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_2555)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_2555)))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_2556) (I32 0) (Str " File \"/h..."))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_2556) (I32 1) (Str " File \"/h..."))) (I32 0) (I32 512))) (domains (ToSet (StreamFlatMap __iruid_2557 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_2554))) (ToStream False (GetField domains (Ref __iruid_2557))))))))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],eigen:Struct{Eigen_phred:Float64}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let __iruid_2570 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains) (Ref va)) (InsertFields (Ref __iruid_2570) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end") (eigen (GetField eigen (GetField __uid_34 (Ref va)))) (end (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (Apply position () Int32 (GetField locus (Ref __iruid_2570))) (Apply length () Int32 (ApplyIR indexArray () String (GetField alleles (Ref __iruid_2570)) (I32 0) (Str " File \"/h...")))) (I32 1)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let __iruid_2574 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end) (Ref va)) (InsertFields (Ref __iruid_2574) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac") (exac (GetField exac (GetField __uid_35 (Ref va)))) (filters (GetField filters (Ref __iruid_2574)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let __iruid_2575 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac) (Ref va)) (InsertFields (Ref __iruid_2575) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds") (g1k (GetField g1k (GetField __uid_36 (Ref va)))) (geneIds (ToSet (StreamMap __iruid_2576 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_2575))) (GetField gene_id (Ref __iruid_2576)))))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],geno2mp:Struct{HPO_Count:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (AggLet __iruid_2577 False (ApplyUnaryPrimOp Bang (IsNA (GetField GT (Ref g)))) (AggLet __iruid_2578 False (GetField AD (Ref g)) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds) (Ref va)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes") (geno2mp (GetField geno2mp (GetField __uid_38 (Ref va)))) (genotypes (ApplyAggOp Collect () ( (MakeStruct (num_alt (If (Ref __iruid_2577) (Apply nNonRefAlleles () Int32 (GetField GT (Ref g))) (I32 -1))) (gq (If (Ref __iruid_2577) (GetField GQ (Ref g)) (NA Int32))) (ab (Let __iruid_2579 (StreamFold __iruid_2580 __iruid_2581 (StreamFilter __iruid_2582 (ToStream False (Ref __iruid_2578)) (ApplyUnaryPrimOp Bang (IsNA (Ref __iruid_2582)))) (I32 0) (ApplyBinaryPrimOp Add (Ref __iruid_2580) (Ref __iruid_2581))) (If (ApplySpecial land () Boolean (ApplySpecial land () Boolean (Ref __iruid_2577) (ApplyComparisonOp NEQ (Ref __iruid_2579) (I32 0))) (ApplyComparisonOp GT (ArrayLen (Ref __iruid_2578)) (I32 1))) (Cast Float64 (ApplyBinaryPrimOp FloatingPointDivide (ApplyIR indexArray () Int32 (GetField AD (Ref g)) (I32 1) (Str " File \"/h...")) (Ref __iruid_2579))) (NA Float64)))) (dp (If (Ref __iruid_2577) (Cast Float64 (ApplySpecial min_ignore_missing () Int32 (GetField DP (Ref g)) (I32 32000))) (NA Float64))) (ad (If (Ref __iruid_2577) (Apply format () String (Str "%s") (MakeTuple (0) (GetField AD (Ref g)))) (NA String))) (pl (If (Ref __iruid_2577) (Apply format () String (Str "%s") (MakeTuple (0) (GetField PL (Ref g)))) (NA String))) (sample_id (GetField s (Ref sa))))))))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],gnomad_exome_coverage:Float64}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes) (Ref va)) None (gnomad_exome_coverage (GetField gnomad_exome_coverage (GetField __uid_41 (Ref va)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage) (Ref va)) None (gnomad_exomes (GetField gnomad_exomes (GetField __uid_42 (Ref va)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],gnomad_genome_coverage:Float32}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes) (Ref va)) None (gnomad_genome_coverage (GetField gnomad_genome_coverage (GetField __uid_43 (Ref va)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let __iruid_2583 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage) (Ref va)) (InsertFields (Ref __iruid_2583) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript") (gnomad_genomes (GetField gnomad_genomes (GetField __uid_44 (Ref va)))) (mainTranscript (If (ApplyComparisonOp EQ (ArrayLen (GetField sortedTranscriptConsequences (Ref __iruid_2583))) (I32 0)) (Literal Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String} ) (Let __iruid_2584 (ApplyIR indexArray () Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32} (GetField sortedTranscriptConsequences (Ref __iruid_2583)) (I32 0) (Str " File \"/h...")) (InsertFields (SelectFields (biotype canonical category cdna_start cdna_end codons gene_id gene_symbol hgvs hgvsc major_consequence major_consequence_rank transcript_id amino_acids domains hgvsp lof lof_flags lof_filter lof_info polyphen_prediction protein_id sift_prediction) (Ref __iruid_2584)) ("biotype" "canonical" "category" "cdna_start" "cdna_end" "codons" "gene_id" "gene_symbol" "hgvs" "hgvsc" "major_consequence" "major_consequence_rank" "transcript_id" "amino_acids" "domains" "hgvsp" "lof" "lof_flags" "lof_filter" "lof_info" "polyphen_prediction" "protein_id" "sift_prediction") (domains (Apply mkString () String (ToSet (ToStream False (GetField domains (Ref __iruid_2584)))) (Str ",")))))))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],mpc:Struct{MPC:String}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let __iruid_2585 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript) (Ref va)) (Let __iruid_2586 (GetField alleles_old (Ref __iruid_2585)) (Let __iruid_2587 (GetField locus_old (Ref __iruid_2585)) (InsertFields (Ref __iruid_2585) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos") (mpc (GetField mpc (GetField __uid_46 (Ref va)))) (originalAltAlleles (ToArray (StreamMap __iruid_2588 (ToStream False (ApplyIR sliceRight () Array[String] (Ref __iruid_2586) (I32 1))) (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply contig () String (Ref __iruid_2587)) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_2587)))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_2586) (I32 0) (Str " File \"/h..."))) (Str "-")) (Ref __iruid_2588))))) (pos (Apply position () Int32 (GetField locus (Ref __iruid_2585))))))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],primate_ai:Struct{score:Float64}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let __iruid_2592 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos) (Ref va)) (Let __iruid_2593 (GetField genotypes (Ref __iruid_2592)) (Let __iruid_2594 (GetField genotypes (Ref __iruid_2592)) (Let __iruid_2595 (GetField genotypes (Ref __iruid_2592)) (InsertFields (Ref __iruid_2592) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt") (primate_ai (GetField primate_ai (GetField __uid_48 (Ref va)))) (ref (ApplyIR indexArray () String (GetField alleles (Ref __iruid_2592)) (I32 0) (Str " File \"/h..."))) (rsid (GetField rsid (Ref __iruid_2592))) (samples_ab (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_2596 (StreamFilter __iruid_2597 (ToStream False (Ref __iruid_2593)) (Let __iruid_2598 (GetField ab (Ref __iruid_2597)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2597)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2598) (F64 100.0)) (F64 0.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2598) (F64 100.0)) (F64 5.0))))) (GetField sample_id (Ref __iruid_2596))))) (5_to_10 (ToSet (StreamMap __iruid_2599 (StreamFilter __iruid_2600 (ToStream False (Ref __iruid_2593)) (Let __iruid_2601 (GetField ab (Ref __iruid_2600)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2600)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2601) (F64 100.0)) (F64 5.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2601) (F64 100.0)) (F64 10.0))))) (GetField sample_id (Ref __iruid_2599))))) (10_to_15 (ToSet (StreamMap __iruid_2602 (StreamFilter __iruid_2603 (ToStream False (Ref __iruid_2593)) (Let __iruid_2604 (GetField ab (Ref __iruid_2603)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2603)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2604) (F64 100.0)) (F64 10.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2604) (F64 100.0)) (F64 15.0))))) (GetField sample_id (Ref __iruid_2602))))) (15_to_20 (ToSet (StreamMap __iruid_2605 (StreamFilter __iruid_2606 (ToStream False (Ref __iruid_2593)) (Let __iruid_2607 (GetField ab (Ref __iruid_2606)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2606)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2607) (F64 100.0)) (F64 15.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2607) (F64 100.0)) (F64 20.0))))) (GetField sample_id (Ref __iruid_2605))))) (20_to_25 (ToSet (StreamMap __iruid_2608 (StreamFilter __iruid_2609 (ToStream False (Ref __iruid_2593)) (Let __iruid_2610 (GetField ab (Ref __iruid_2609)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2609)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2610) (F64 100.0)) (F64 20.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2610) (F64 100.0)) (F64 25.0))))) (GetField sample_id (Ref __iruid_2608))))) (25_to_30 (ToSet (StreamMap __iruid_2611 (StreamFilter __iruid_2612 (ToStream False (Ref __iruid_2593)) (Let __iruid_2613 (GetField ab (Ref __iruid_2612)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2612)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2613) (F64 100.0)) (F64 25.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2613) (F64 100.0)) (F64 30.0))))) (GetField sample_id (Ref __iruid_2611))))) (30_to_35 (ToSet (StreamMap __iruid_2614 (StreamFilter __iruid_2615 (ToStream False (Ref __iruid_2593)) (Let __iruid_2616 (GetField ab (Ref __iruid_2615)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2615)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2616) (F64 100.0)) (F64 30.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2616) (F64 100.0)) (F64 35.0))))) (GetField sample_id (Ref __iruid_2614))))) (35_to_40 (ToSet (StreamMap __iruid_2617 (StreamFilter __iruid_2618 (ToStream False (Ref __iruid_2593)) (Let __iruid_2619 (GetField ab (Ref __iruid_2618)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2618)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2619) (F64 100.0)) (F64 35.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2619) (F64 100.0)) (F64 40.0))))) (GetField sample_id (Ref __iruid_2617))))) (40_to_45 (ToSet (StreamMap __iruid_2620 (StreamFilter __iruid_2621 (ToStream False (Ref __iruid_2593)) (Let __iruid_2622 (GetField ab (Ref __iruid_2621)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2621)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2622) (F64 100.0)) (F64 40.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2622) (F64 100.0)) (F64 45.0))))) (GetField sample_id (Ref __iruid_2620))))))) (samples_gq (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_2623 (StreamFilter __iruid_2624 (ToStream False (Ref __iruid_2594)) (Let __iruid_2625 (GetField gq (Ref __iruid_2624)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2625) (I32 0)) (ApplyComparisonOp LT (Ref __iruid_2625) (I32 5))))) (GetField sample_id (Ref __iruid_2623))))) (5_to_10 (ToSet (StreamMap __iruid_2626 (StreamFilter __iruid_2627 (ToStream False (Ref __iruid_2594)) (Let __iruid_2628 (GetField gq (Ref __iruid_2627)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2628) (I32 5)) (ApplyComparisonOp LT (Ref __iruid_2628) (I32 10))))) (GetField sample_id (Ref __iruid_2626))))) (10_to_15 (ToSet (StreamMap __iruid_2629 (StreamFilter __iruid_2630 (ToStream False (Ref __iruid_2594)) (Let __iruid_2631 (GetField gq (Ref __iruid_2630)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2631) (I32 10)) (ApplyComparisonOp LT (Ref __iruid_2631) (I32 15))))) (GetField sample_id (Ref __iruid_2629))))) (15_to_20 (ToSet (StreamMap __iruid_2632 (StreamFilter __iruid_2633 (ToStream False (Ref __iruid_2594)) (Let __iruid_2634 (GetField gq (Ref __iruid_2633)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2634) (I32 15)) (ApplyComparisonOp LT (Ref __iruid_2634) (I32 20))))) (GetField sample_id (Ref __iruid_2632))))) (20_to_25 (ToSet (StreamMap __iruid_2635 (StreamFilter __iruid_2636 (ToStream False (Ref __iruid_2594)) (Let __iruid_2637 (GetField gq (Ref __iruid_2636)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2637) (I32 20)) (ApplyComparisonOp LT (Ref __iruid_2637) (I32 25))))) (GetField sample_id (Ref __iruid_2635))))) (25_to_30 (ToSet (StreamMap __iruid_2638 (StreamFilter __iruid_2639 (ToStream False (Ref __iruid_2594)) (Let __iruid_2640 (GetField gq (Ref __iruid_2639)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2640) (I32 25)) (ApplyComparisonOp LT (Ref __iruid_2640) (I32 30))))) (GetField sample_id (Ref __iruid_2638))))) (30_to_35 (ToSet (StreamMap __iruid_2641 (StreamFilter __iruid_2642 (ToStream False (Ref __iruid_2594)) (Let __iruid_2643 (GetField gq (Ref __iruid_2642)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2643) (I32 30)) (ApplyComparisonOp LT (Ref __iruid_2643) (I32 35))))) (GetField sample_id (Ref __iruid_2641))))) (35_to_40 (ToSet (StreamMap __iruid_2644 (StreamFilter __iruid_2645 (ToStream False (Ref __iruid_2594)) (Let __iruid_2646 (GetField gq (Ref __iruid_2645)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2646) (I32 35)) (ApplyComparisonOp LT (Ref __iruid_2646) (I32 40))))) (GetField sample_id (Ref __iruid_2644))))) (40_to_45 (ToSet (StreamMap __iruid_2647 (StreamFilter __iruid_2648 (ToStream False (Ref __iruid_2594)) (Let __iruid_2649 (GetField gq (Ref __iruid_2648)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2649) (I32 40)) (ApplyComparisonOp LT (Ref __iruid_2649) (I32 45))))) (GetField sample_id (Ref __iruid_2647))))) (45_to_50 (ToSet (StreamMap __iruid_2650 (StreamFilter __iruid_2651 (ToStream False (Ref __iruid_2594)) (Let __iruid_2652 (GetField gq (Ref __iruid_2651)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2652) (I32 45)) (ApplyComparisonOp LT (Ref __iruid_2652) (I32 50))))) (GetField sample_id (Ref __iruid_2650))))) (50_to_55 (ToSet (StreamMap __iruid_2653 (StreamFilter __iruid_2654 (ToStream False (Ref __iruid_2594)) (Let __iruid_2655 (GetField gq (Ref __iruid_2654)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2655) (I32 50)) (ApplyComparisonOp LT (Ref __iruid_2655) (I32 55))))) (GetField sample_id (Ref __iruid_2653))))) (55_to_60 (ToSet (StreamMap __iruid_2656 (StreamFilter __iruid_2657 (ToStream False (Ref __iruid_2594)) (Let __iruid_2658 (GetField gq (Ref __iruid_2657)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2658) (I32 55)) (ApplyComparisonOp LT (Ref __iruid_2658) (I32 60))))) (GetField sample_id (Ref __iruid_2656))))) (60_to_65 (ToSet (StreamMap __iruid_2659 (StreamFilter __iruid_2660 (ToStream False (Ref __iruid_2594)) (Let __iruid_2661 (GetField gq (Ref __iruid_2660)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2661) (I32 60)) (ApplyComparisonOp LT (Ref __iruid_2661) (I32 65))))) (GetField sample_id (Ref __iruid_2659))))) (65_to_70 (ToSet (StreamMap __iruid_2662 (StreamFilter __iruid_2663 (ToStream False (Ref __iruid_2594)) (Let __iruid_2664 (GetField gq (Ref __iruid_2663)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2664) (I32 65)) (ApplyComparisonOp LT (Ref __iruid_2664) (I32 70))))) (GetField sample_id (Ref __iruid_2662))))) (70_to_75 (ToSet (StreamMap __iruid_2665 (StreamFilter __iruid_2666 (ToStream False (Ref __iruid_2594)) (Let __iruid_2667 (GetField gq (Ref __iruid_2666)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2667) (I32 70)) (ApplyComparisonOp LT (Ref __iruid_2667) (I32 75))))) (GetField sample_id (Ref __iruid_2665))))) (75_to_80 (ToSet (StreamMap __iruid_2668 (StreamFilter __iruid_2669 (ToStream False (Ref __iruid_2594)) (Let __iruid_2670 (GetField gq (Ref __iruid_2669)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2670) (I32 75)) (ApplyComparisonOp LT (Ref __iruid_2670) (I32 80))))) (GetField sample_id (Ref __iruid_2668))))) (80_to_85 (ToSet (StreamMap __iruid_2671 (StreamFilter __iruid_2672 (ToStream False (Ref __iruid_2594)) (Let __iruid_2673 (GetField gq (Ref __iruid_2672)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2673) (I32 80)) (ApplyComparisonOp LT (Ref __iruid_2673) (I32 85))))) (GetField sample_id (Ref __iruid_2671))))) (85_to_90 (ToSet (StreamMap __iruid_2674 (StreamFilter __iruid_2675 (ToStream False (Ref __iruid_2594)) (Let __iruid_2676 (GetField gq (Ref __iruid_2675)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2676) (I32 85)) (ApplyComparisonOp LT (Ref __iruid_2676) (I32 90))))) (GetField sample_id (Ref __iruid_2674))))) (90_to_95 (ToSet (StreamMap __iruid_2677 (StreamFilter __iruid_2678 (ToStream False (Ref __iruid_2594)) (Let __iruid_2679 (GetField gq (Ref __iruid_2678)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2679) (I32 90)) (ApplyComparisonOp LT (Ref __iruid_2679) (I32 95))))) (GetField sample_id (Ref __iruid_2677))))))) (samples_no_call (ToSet (StreamMap __iruid_2680 (StreamFilter __iruid_2681 (ToStream False (GetField genotypes (Ref __iruid_2592))) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2681)) (I32 -1))) (GetField sample_id (Ref __iruid_2680))))) (samples_num_alt (MakeStruct (1 (ToSet (StreamMap __iruid_2682 (StreamFilter __iruid_2683 (ToStream False (Ref __iruid_2595)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2683)) (I32 1))) (GetField sample_id (Ref __iruid_2682))))) (2 (ToSet (StreamMap __iruid_2684 (StreamFilter __iruid_2685 (ToStream False (Ref __iruid_2595)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2685)) (I32 2))) (GetField sample_id (Ref __iruid_2684))))))))))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],splice_ai:Struct{delta_score:Float32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let __iruid_2689 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt) (Ref va)) (InsertFields (Ref __iruid_2689) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "splice_ai" "start") (splice_ai (GetField splice_ai (GetField __uid_111 (Ref va)))) (start (Apply position () Int32 (GetField locus (Ref __iruid_2689))))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],topmed:Struct{AC:Int32,AF:Float64,AN:Int32,Hom:Int32,Het:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let __iruid_2690 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start) (Ref va)) (Let __iruid_2691 (GetField locus (Ref __iruid_2690)) (Let __iruid_2692 (GetField alleles (Ref __iruid_2690)) (Let __iruid_2693 (GetField locus (Ref __iruid_2690)) (Let __iruid_2694 (GetField locus (Ref __iruid_2690)) (Let __iruid_2695 (GetField locus (Ref __iruid_2690)) (InsertFields (SelectFields (locus alleles aIndex AC AF alt AN cadd clinvar codingGeneIds contig dbnsfp docId domains eigen end exac filters g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref rsid samples_ab samples_gq samples_no_call samples_num_alt sortedTranscriptConsequences splice_ai start vep) (Ref __iruid_2690)) ("locus" "alleles" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "filters" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "rsid" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "sortedTranscriptConsequences" "splice_ai" "start" "topmed" "transcriptConsequenceTerms" "transcriptIds" "utrVariantAnnotation" "variantId" "vep" "xpos" "xstart" "xstop") (topmed (GetField topmed (GetField __uid_112 (Ref va)))) (transcriptConsequenceTerms (ToSet (StreamFlatMap __iruid_2696 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_2690))) (ToStream False (GetField consequence_terms (Ref __iruid_2696)))))) (transcriptIds (ToSet (StreamMap __iruid_2697 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_2690))) (GetField transcript_id (Ref __iruid_2697))))) (utrVariantAnnotation (ToArray (StreamMap __iruid_2698 (StreamFilter __iruid_2699 (ToStream False (GetField transcript_consequences (GetField vep (Ref __iruid_2690)))) (Let __iruid_2700 (Str "5_prime_UT...") (StreamFold __iruid_2701 __iruid_2702 (ToStream False (GetField consequence_terms (Ref __iruid_2699))) (False) (ApplySpecial lor () Boolean (Ref __iruid_2701) (ApplyComparisonOp EQWithNA (Ref __iruid_2702) (Ref __iruid_2700)))))) (MakeStruct (existing_inframe_oorfs (GetField existing_inframe_oorfs (Ref __iruid_2698))) (existing_outofframe_oorfs (GetField existing_outofframe_oorfs (Ref __iruid_2698))) (existing_uorfs (GetField existing_uorfs (Ref __iruid_2698))) (five_prime_utr_variant_consequence (GetField five_prime_utr_variant_consequence (Ref __iruid_2698))) (five_prime_utr_variant_annotation (GetField five_prime_utr_variant_annotation (Ref __iruid_2698))))))) (variantId (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_2691)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_2691)))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_2692) (I32 0) (Str " File \"/h..."))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_2692) (I32 1) (Str " File \"/h...")))) (xpos (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_2703 (Apply replace () String (Apply contig () String (Ref __iruid_2693)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_2703) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_2703) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __iruid_2703) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_2703))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_2693))))) (xstart (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_2704 (Apply replace () String (Apply contig () String (Ref __iruid_2694)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_2704) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_2704) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __iruid_2704) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_2704))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_2694))))) (xstop (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_2705 (Apply replace () String (Apply contig () String (Ref __iruid_2695)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_2705) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_2705) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __iruid_2705) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_2705))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_2695)))) (Cast Int64 (Apply length () Int32 (ApplyIR indexArray () String (GetField alleles (Ref __iruid_2690)) (I32 0) (Str " File \"/h..."))))) (I64 1))))))))))) (InsertFields (Ref global) None (sourceFilePath (Str "s3://seqr-...")) (genomeVersion (Str "38")) (sampleType (Str "WGS")) (hail_version (Str "0.2.57"))))) 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- LoweringTransformation : 1.573s, total 1.612s, tagged coverage 93.8 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR -- Verify : 0.645ms, total 1.613s 2022-04-01 03:25:18 root: INFO: Timer: Time taken for optimize: relationalLowerer, initial IR : 1.576s, total 1.613s, tagged coverage 93.7 2022-04-01 03:25:19 root: INFO: Timer: Time taken for LowerMatrixToTable -- Verify : 0.564ms, total 1.635s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for LowerMatrixToTable -- LoweringTransformation : 45.285ms, total 1.681s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for LowerMatrixToTable -- Verify : 2.102ms, total 1.683s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for LowerMatrixToTable : 48.451ms, total 1.683s, tagged coverage 99.0 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- Verify : 0.733ms, total 1.711s 2022-04-01 03:25:19 root: INFO: optimize optimize: relationalLowerer, after LowerMatrixToTable: before: IR size 1770: (TableWrite "{\"writer\":{\"path\":\"s3://seqr-dp-build--prod/mt-hail-luigi/SEQR2_PROD/IUIS_PANELv1_20220321.mt\",\"overwrite\":true,\"stageLocally\":false,\"codecSpecJSONStr\":null,\"partitions\":null,\"partitionsTypeStr\":null},\"colsFieldName\":\"__cols\",\"entriesFieldName\":\"the entries! [877f12a8827e18f61222c6c8c5fb04a8]\",\"colKey\":[\"s\"]}" (TableMapGlobals (TableMapRows (TableLeftJoinRightDistinct __uid_112 (TableMapRows (TableLeftJoinRightDistinct __uid_111 (TableMapRows (TableLeftJoinRightDistinct __uid_48 (TableMapRows (TableLeftJoinRightDistinct __uid_46 (TableMapRows (TableLeftJoinRightDistinct __uid_44 (TableMapRows (TableLeftJoinRightDistinct __uid_43 (TableMapRows (TableLeftJoinRightDistinct __uid_42 (TableMapRows (TableLeftJoinRightDistinct __uid_41 (TableMapRows (TableLeftJoinRightDistinct __uid_38 (TableMapRows (TableLeftJoinRightDistinct __uid_36 (TableMapRows (TableLeftJoinRightDistinct __uid_35 (TableMapRows (TableLeftJoinRightDistinct __uid_34 (TableMapRows (TableLeftJoinRightDistinct __uid_31 (TableMapRows (TableLeftJoinRightDistinct __uid_8 (TableLeftJoinRightDistinct __uid_7 (TableLeftJoinRightDistinct __uid_6 (TableMapRows (TableLeftJoinRightDistinct __uid_5 (TableMapRows (TableLeftJoinRightDistinct __uid_4 (TableMapGlobals (TableKeyBy (locus alleles) False (TableMapRows (TableKeyBy () False (TableMapRows (TableRead Table{global:Struct{__cols:Array[Struct{s:String}]},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]}} False "{\"files\":[\"s3://seqr-dp-data--prod/vcf/prod/IUIS_PANELv1_20220321.vcf.gz\"],\"callFields\":[\"PGT\"],\"entryFloatTypeName\":\"Float64\",\"minPartitions\":500,\"rg\":\"GRCh38\",\"contigRecoding\":{},\"arrayElementsRequired\":false,\"skipInvalidLoci\":false,\"gzAsBGZ\":true,\"forceGZ\":false,\"filterAndReplace\":{},\"partitionsJSON\":null,\"name\":\"MatrixVCFReader\"}") (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2952 (MakeStruct) (InsertFields (SelectFields (locus alleles rsid filters info) (Ref row)) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old") (a_index (I32 1)) (alleles_old (GetField alleles (SelectFields (locus alleles rsid filters info) (Ref row)))) (locus_old (GetField locus (SelectFields (locus alleles rsid filters info) (Ref row)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row))))))) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2953 (MakeStruct) (Let __iruid_2515 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (Ref row))) (GetField alleles (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (Ref row)))) (InsertFields (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (Ref row)) None (locus (GetField locus (Ref __iruid_2515))) (alleles (GetField alleles (Ref __iruid_2515)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row))))))) (InsertFields (InsertFields (SelectFields () (Ref global)) None (gencodeVersion (Str "25"))) None (__cols (GetField __cols (Ref global))))) (TableLiteral)) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2954 (MakeStruct) (Let __iruid_2516 (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old __uid_4) (Ref row))) (InsertFields (Ref __iruid_2516) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN") (vep (GetField vep (GetField __uid_4 (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old __uid_4) (Ref row))))) (aIndex (GetField a_index (Ref __iruid_2516))) (AC (ApplyIR indexArray () Int32 (GetField AC (GetField info (Ref __iruid_2516))) (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_2516)) (I32 1)) (Str " File \"/h..."))) (AF (ApplyIR indexArray () Float64 (GetField AF (GetField info (Ref __iruid_2516))) (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_2516)) (I32 1)) (Str " File \"/h..."))) (alt (ApplyIR indexArray () String (GetField alleles (Ref __iruid_2516)) (I32 1) (Str " File \"/h..."))) (AN (GetField AN (GetField info (Ref __iruid_2516))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],cadd:Struct{PHRED:Float32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2964 (MakeStruct) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN) (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old vep aIndex AC AF alt AN __uid_5) (Ref row))) None (cadd (GetField cadd (GetField __uid_5 (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old vep aIndex AC AF alt AN __uid_5) (Ref row))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],info:Struct{ALLELEID:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht\",\"name\":\"TableNativeReader\"}")) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],info:Struct{CLNSIG:Array[String]}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht\",\"name\":\"TableNativeReader\"}")) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],gold_stars:Int32}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht\",\"name\":\"TableNativeReader\"}")) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2965 (MakeStruct) (Let __iruid_2526 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd) (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd __uid_6 __uid_7 __uid_8) (Ref row))) (Let __iruid_2527 (GetField vep (Ref __iruid_2526)) (Let __iruid_2528 (ToArray (StreamMap __iruid_2529 (ToStream False (ArraySort __iruid_2530 __iruid_2531 (StreamMap __iruid_2532 (StreamFilter __iruid_2533 (StreamMap __iruid_2534 (ToStream False (GetField transcript_consequences (Ref __iruid_2527))) (Let __iruid_2535 (GetField consequence_terms (Ref __iruid_2534)) (InsertFields (SelectFields (biotype canonical cdna_start cdna_end codons gene_id gene_symbol hgvsc hgvsp transcript_id amino_acids lof lof_filter lof_flags lof_info polyphen_prediction protein_id protein_start sift_prediction) (Ref __iruid_2534)) None (consequence_terms (ToArray (StreamFilter __iruid_2536 (ToStream False (Ref __iruid_2535)) (ApplyUnaryPrimOp Bang (ApplyIR contains () Boolean (ToSet (ToStream False (Literal Array[String] ))) (Ref __iruid_2536)))))) (domains (ToArray (StreamMap __iruid_2537 (ToStream False (GetField domains (Ref __iruid_2534))) (Apply concat () String (Apply concat () String (GetField db (Ref __iruid_2537)) (Str ":")) (GetField name (Ref __iruid_2537)))))) (major_consequence (If (ApplyComparisonOp GT (ArrayLen (Ref __iruid_2535)) (I32 0)) (ApplyIR indexArray () String (ToArray (StreamMap __iruid_2538 (ToStream False (ArraySort __iruid_2539 __iruid_2540 (StreamMap __iruid_2541 (ToStream False (GetField consequence_terms (Ref __iruid_2534))) (MakeTuple (0 1) (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (Ref __iruid_2541)) (Ref __iruid_2541))) (If (IsNA (GetTupleElement 0 (Ref __iruid_2539))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_2540))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_2539)) (GetTupleElement 0 (Ref __iruid_2540))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_2538)))) (I32 0) (Str " File \"/h...")) (NA String)))))) (ApplyComparisonOp GT (ArrayLen (GetField consequence_terms (Ref __iruid_2533))) (I32 0))) (Let __iruid_2542 (GetField major_consequence (Ref __iruid_2532)) (Let __iruid_2543 (InsertFields (Ref __iruid_2532) None (category (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (Ref __iruid_2542)) (I32 4)) (Str "lof") (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (GetField major_consequence (Ref __iruid_2532))) (I32 11)) (Str "missense") (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (GetField major_consequence (Ref __iruid_2532))) (I32 17)) (Str "synonymous") (Str "other"))))) (hgvs (If (ApplySpecial lor () Boolean (IsNA (GetField hgvsp (Ref __iruid_2532))) (ApplyIR contains () Boolean (ToSet (ToStream False (Literal Array[String] ))) (Ref __iruid_2542))) (ApplyIR indexArray () String (Apply split () Array[String] (GetField hgvsc (Ref __iruid_2532)) (Str ":")) (I32 -1) (Str " File \"/h...")) (Let __iruid_2544 (GetField hgvsp (Ref __iruid_2532)) (If (ApplySpecial lor () Boolean (Apply contains () Boolean (Ref __iruid_2544) (Str "=")) (Apply contains () Boolean (Ref __iruid_2544) (Str "%3D"))) (Let __iruid_2545 (Apply mkString () String (ToArray (StreamMap __iruid_2546 (ToStream False (Apply split () Array[String] (GetField amino_acids (Ref __iruid_2532)) (Str ""))) (ApplyIR get () String (Literal Dict[String,String] ) (Ref __iruid_2546)))) (Str "")) (Apply concat () String (Apply concat () String (Apply concat () String (Str "p.") (Ref __iruid_2545)) (Apply str () String (GetField protein_start (Ref __iruid_2532)))) (Ref __iruid_2545))) (ApplyIR indexArray () String (Apply split () Array[String] (GetField hgvsp (Ref __iruid_2532)) (Str ":")) (I32 -1) (Str " File \"/h...")))))) (major_consequence_rank (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (Ref __iruid_2542)))) (MakeTuple (0 1) (Let __iruid_2547 (ApplyComparisonOp EQ (Coalesce (GetField canonical (Ref __iruid_2543)) (I32 0)) (I32 1)) (Let __iruid_2548 (ApplyIR contains () Boolean (ToSet (ToStream False (GetField consequence_terms (Ref __iruid_2543)))) (GetField most_severe_consequence (Ref __iruid_2527))) (If (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_2543)) (Str "")) (Str "protein_co...")) (If (Ref __iruid_2548) (If (Ref __iruid_2547) (I32 1) (I32 2)) (If (Ref __iruid_2547) (I32 3) (I32 4))) (If (Ref __iruid_2548) (If (Ref __iruid_2547) (I32 5) (I32 6)) (If (Ref __iruid_2547) (I32 7) (I32 8)))))) (Ref __iruid_2543))))) (If (IsNA (GetTupleElement 0 (Ref __iruid_2530))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_2531))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_2530)) (GetTupleElement 0 (Ref __iruid_2531))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_2529)))) (Let __iruid_2549 (ToArray (StreamMap __iruid_2550 (StreamRange False (I32 0) (ArrayLen (Ref __iruid_2528)) (I32 1)) (Let __iruid_2551 (MakeTuple (0 1) (Ref __iruid_2550) (ApplyIR indexArray () Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32} (Ref __iruid_2528) (Ref __iruid_2550) (Str " File \"/h..."))) (InsertFields (GetTupleElement 1 (Ref __iruid_2551)) None (transcript_rank (GetTupleElement 0 (Ref __iruid_2551))))))) (InsertFields (Ref __iruid_2526) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig") (clinvar (MakeStruct (allele_id (GetField ALLELEID (GetField info (GetField __uid_6 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd __uid_6 __uid_7 __uid_8) (Ref row)))))) (clinical_significance (Apply mkString () String (GetField CLNSIG (GetField info (GetField __uid_7 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd __uid_6 __uid_7 __uid_8) (Ref row))))) (Str ","))) (gold_stars (GetField gold_stars (GetField __uid_8 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd __uid_6 __uid_7 __uid_8) (Ref row))))))) (sortedTranscriptConsequences (Ref __iruid_2549)) (codingGeneIds (ToSet (StreamMap __iruid_2552 (StreamFilter __iruid_2553 (ToStream False (Ref __iruid_2549)) (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_2553)) (Str "")) (Str "protein_co..."))) (GetField gene_id (Ref __iruid_2552))))) (contig (Apply replace () String (Apply contig () String (GetField locus (Ref __iruid_2526))) (Str "^chr") (Str ""))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2966 (MakeStruct) (Let __iruid_2554 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig) (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig __uid_31) (Ref row))) (Let __iruid_2555 (GetField locus (Ref __iruid_2554)) (Let __iruid_2556 (GetField alleles (Ref __iruid_2554)) (InsertFields (Ref __iruid_2554) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains") (dbnsfp (GetField dbnsfp (GetField __uid_31 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig __uid_31) (Ref row))))) (docId (ApplyIR slice () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_2555)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_2555)))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_2556) (I32 0) (Str " File \"/h..."))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_2556) (I32 1) (Str " File \"/h..."))) (I32 0) (I32 512))) (domains (ToSet (StreamFlatMap __iruid_2557 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_2554))) (ToStream False (GetField domains (Ref __iruid_2557))))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],eigen:Struct{Eigen_phred:Float64}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2979 (MakeStruct) (Let __iruid_2570 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains) (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains __uid_34) (Ref row))) (InsertFields (Ref __iruid_2570) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end") (eigen (GetField eigen (GetField __uid_34 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains __uid_34) (Ref row))))) (end (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (Apply position () Int32 (GetField locus (Ref __iruid_2570))) (Apply length () Int32 (ApplyIR indexArray () String (GetField alleles (Ref __iruid_2570)) (I32 0) (Str " File \"/h...")))) (I32 1)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2983 (MakeStruct) (Let __iruid_2574 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end) (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end __uid_35) (Ref row))) (InsertFields (Ref __iruid_2574) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac") (exac (GetField exac (GetField __uid_35 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end __uid_35) (Ref row))))) (filters (GetField filters (Ref __iruid_2574)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2984 (MakeStruct) (Let __iruid_2575 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac) (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac __uid_36) (Ref row))) (InsertFields (Ref __iruid_2575) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds") (g1k (GetField g1k (GetField __uid_36 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac __uid_36) (Ref row))))) (geneIds (ToSet (StreamMap __iruid_2576 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_2575))) (GetField gene_id (Ref __iruid_2576)))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],geno2mp:Struct{HPO_Count:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2985 (MakeStruct) (StreamAgg i (ToStream False (ToArray (StreamFilter i (ToStream False (ToArray (StreamRange False (I32 0) (ArrayLen (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row))) (I32 1)))) (ApplyUnaryPrimOp Bang (IsNA (ArrayRef (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)) (Ref i) (Str ""))))))) (AggLet sa False (ArrayRef (GetField __cols (Ref global)) (Ref i) (Str "")) (AggLet g False (ArrayRef (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)) (Ref i) (Str "")) (AggLet __iruid_2577 False (ApplyUnaryPrimOp Bang (IsNA (GetField GT (Ref g)))) (AggLet __iruid_2578 False (GetField AD (Ref g)) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds) (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds __uid_38) (Ref row))) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes") (geno2mp (GetField geno2mp (GetField __uid_38 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds __uid_38) (Ref row))))) (genotypes (ApplyAggOp Collect () ( (MakeStruct (num_alt (If (Ref __iruid_2577) (Apply nNonRefAlleles () Int32 (GetField GT (Ref g))) (I32 -1))) (gq (If (Ref __iruid_2577) (GetField GQ (Ref g)) (NA Int32))) (ab (Let __iruid_2579 (StreamFold __iruid_2580 __iruid_2581 (StreamFilter __iruid_2582 (ToStream False (Ref __iruid_2578)) (ApplyUnaryPrimOp Bang (IsNA (Ref __iruid_2582)))) (I32 0) (ApplyBinaryPrimOp Add (Ref __iruid_2580) (Ref __iruid_2581))) (If (ApplySpecial land () Boolean (ApplySpecial land () Boolean (Ref __iruid_2577) (ApplyComparisonOp NEQ (Ref __iruid_2579) (I32 0))) (ApplyComparisonOp GT (ArrayLen (Ref __iruid_2578)) (I32 1))) (Cast Float64 (ApplyBinaryPrimOp FloatingPointDivide (ApplyIR indexArray () Int32 (GetField AD (Ref g)) (I32 1) (Str " File \"/h...")) (Ref __iruid_2579))) (NA Float64)))) (dp (If (Ref __iruid_2577) (Cast Float64 (ApplySpecial min_ignore_missing () Int32 (GetField DP (Ref g)) (I32 32000))) (NA Float64))) (ad (If (Ref __iruid_2577) (Apply format () String (Str "%s") (MakeTuple (0) (GetField AD (Ref g)))) (NA String))) (pl (If (Ref __iruid_2577) (Apply format () String (Str "%s") (MakeTuple (0) (GetField PL (Ref g)))) (NA String))) (sample_id (GetField s (Ref sa)))))))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],gnomad_exome_coverage:Float64}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2986 (MakeStruct) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes) (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes __uid_41) (Ref row))) None (gnomad_exome_coverage (GetField gnomad_exome_coverage (GetField __uid_41 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes __uid_41) (Ref row))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2987 (MakeStruct) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage) (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage __uid_42) (Ref row))) None (gnomad_exomes (GetField gnomad_exomes (GetField __uid_42 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage __uid_42) (Ref row))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],gnomad_genome_coverage:Float32}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2988 (MakeStruct) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes) (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes __uid_43) (Ref row))) None (gnomad_genome_coverage (GetField gnomad_genome_coverage (GetField __uid_43 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes __uid_43) (Ref row))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2989 (MakeStruct) (Let __iruid_2583 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage) (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage __uid_44) (Ref row))) (InsertFields (Ref __iruid_2583) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript") (gnomad_genomes (GetField gnomad_genomes (GetField __uid_44 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage __uid_44) (Ref row))))) (mainTranscript (If (ApplyComparisonOp EQ (ArrayLen (GetField sortedTranscriptConsequences (Ref __iruid_2583))) (I32 0)) (Literal Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String} ) (Let __iruid_2584 (ApplyIR indexArray () Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32} (GetField sortedTranscriptConsequences (Ref __iruid_2583)) (I32 0) (Str " File \"/h...")) (InsertFields (SelectFields (biotype canonical category cdna_start cdna_end codons gene_id gene_symbol hgvs hgvsc major_consequence major_consequence_rank transcript_id amino_acids domains hgvsp lof lof_flags lof_filter lof_info polyphen_prediction protein_id sift_prediction) (Ref __iruid_2584)) ("biotype" "canonical" "category" "cdna_start" "cdna_end" "codons" "gene_id" "gene_symbol" "hgvs" "hgvsc" "major_consequence" "major_consequence_rank" "transcript_id" "amino_acids" "domains" "hgvsp" "lof" "lof_flags" "lof_filter" "lof_info" "polyphen_prediction" "protein_id" "sift_prediction") (domains (Apply mkString () String (ToSet (ToStream False (GetField domains (Ref __iruid_2584)))) (Str ",")))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],mpc:Struct{MPC:String}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2990 (MakeStruct) (Let __iruid_2585 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript) (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript __uid_46) (Ref row))) (Let __iruid_2586 (GetField alleles_old (Ref __iruid_2585)) (Let __iruid_2587 (GetField locus_old (Ref __iruid_2585)) (InsertFields (Ref __iruid_2585) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos") (mpc (GetField mpc (GetField __uid_46 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript __uid_46) (Ref row))))) (originalAltAlleles (ToArray (StreamMap __iruid_2588 (ToStream False (ApplyIR sliceRight () Array[String] (Ref __iruid_2586) (I32 1))) (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply contig () String (Ref __iruid_2587)) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_2587)))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_2586) (I32 0) (Str " File \"/h..."))) (Str "-")) (Ref __iruid_2588))))) (pos (Apply position () Int32 (GetField locus (Ref __iruid_2585))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],primate_ai:Struct{score:Float64}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2994 (MakeStruct) (Let __iruid_2592 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos) (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos __uid_48) (Ref row))) (Let __iruid_2593 (GetField genotypes (Ref __iruid_2592)) (Let __iruid_2594 (GetField genotypes (Ref __iruid_2592)) (Let __iruid_2595 (GetField genotypes (Ref __iruid_2592)) (InsertFields (Ref __iruid_2592) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt") (primate_ai (GetField primate_ai (GetField __uid_48 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos __uid_48) (Ref row))))) (ref (ApplyIR indexArray () String (GetField alleles (Ref __iruid_2592)) (I32 0) (Str " File \"/h..."))) (rsid (GetField rsid (Ref __iruid_2592))) (samples_ab (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_2596 (StreamFilter __iruid_2597 (ToStream False (Ref __iruid_2593)) (Let __iruid_2598 (GetField ab (Ref __iruid_2597)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2597)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2598) (F64 100.0)) (F64 0.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2598) (F64 100.0)) (F64 5.0))))) (GetField sample_id (Ref __iruid_2596))))) (5_to_10 (ToSet (StreamMap __iruid_2599 (StreamFilter __iruid_2600 (ToStream False (Ref __iruid_2593)) (Let __iruid_2601 (GetField ab (Ref __iruid_2600)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2600)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2601) (F64 100.0)) (F64 5.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2601) (F64 100.0)) (F64 10.0))))) (GetField sample_id (Ref __iruid_2599))))) (10_to_15 (ToSet (StreamMap __iruid_2602 (StreamFilter __iruid_2603 (ToStream False (Ref __iruid_2593)) (Let __iruid_2604 (GetField ab (Ref __iruid_2603)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2603)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2604) (F64 100.0)) (F64 10.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2604) (F64 100.0)) (F64 15.0))))) (GetField sample_id (Ref __iruid_2602))))) (15_to_20 (ToSet (StreamMap __iruid_2605 (StreamFilter __iruid_2606 (ToStream False (Ref __iruid_2593)) (Let __iruid_2607 (GetField ab (Ref __iruid_2606)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2606)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2607) (F64 100.0)) (F64 15.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2607) (F64 100.0)) (F64 20.0))))) (GetField sample_id (Ref __iruid_2605))))) (20_to_25 (ToSet (StreamMap __iruid_2608 (StreamFilter __iruid_2609 (ToStream False (Ref __iruid_2593)) (Let __iruid_2610 (GetField ab (Ref __iruid_2609)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2609)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2610) (F64 100.0)) (F64 20.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2610) (F64 100.0)) (F64 25.0))))) (GetField sample_id (Ref __iruid_2608))))) (25_to_30 (ToSet (StreamMap __iruid_2611 (StreamFilter __iruid_2612 (ToStream False (Ref __iruid_2593)) (Let __iruid_2613 (GetField ab (Ref __iruid_2612)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2612)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2613) (F64 100.0)) (F64 25.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2613) (F64 100.0)) (F64 30.0))))) (GetField sample_id (Ref __iruid_2611))))) (30_to_35 (ToSet (StreamMap __iruid_2614 (StreamFilter __iruid_2615 (ToStream False (Ref __iruid_2593)) (Let __iruid_2616 (GetField ab (Ref __iruid_2615)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2615)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2616) (F64 100.0)) (F64 30.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2616) (F64 100.0)) (F64 35.0))))) (GetField sample_id (Ref __iruid_2614))))) (35_to_40 (ToSet (StreamMap __iruid_2617 (StreamFilter __iruid_2618 (ToStream False (Ref __iruid_2593)) (Let __iruid_2619 (GetField ab (Ref __iruid_2618)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2618)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2619) (F64 100.0)) (F64 35.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2619) (F64 100.0)) (F64 40.0))))) (GetField sample_id (Ref __iruid_2617))))) (40_to_45 (ToSet (StreamMap __iruid_2620 (StreamFilter __iruid_2621 (ToStream False (Ref __iruid_2593)) (Let __iruid_2622 (GetField ab (Ref __iruid_2621)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2621)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_2622) (F64 100.0)) (F64 40.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_2622) (F64 100.0)) (F64 45.0))))) (GetField sample_id (Ref __iruid_2620))))))) (samples_gq (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_2623 (StreamFilter __iruid_2624 (ToStream False (Ref __iruid_2594)) (Let __iruid_2625 (GetField gq (Ref __iruid_2624)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2625) (I32 0)) (ApplyComparisonOp LT (Ref __iruid_2625) (I32 5))))) (GetField sample_id (Ref __iruid_2623))))) (5_to_10 (ToSet (StreamMap __iruid_2626 (StreamFilter __iruid_2627 (ToStream False (Ref __iruid_2594)) (Let __iruid_2628 (GetField gq (Ref __iruid_2627)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2628) (I32 5)) (ApplyComparisonOp LT (Ref __iruid_2628) (I32 10))))) (GetField sample_id (Ref __iruid_2626))))) (10_to_15 (ToSet (StreamMap __iruid_2629 (StreamFilter __iruid_2630 (ToStream False (Ref __iruid_2594)) (Let __iruid_2631 (GetField gq (Ref __iruid_2630)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2631) (I32 10)) (ApplyComparisonOp LT (Ref __iruid_2631) (I32 15))))) (GetField sample_id (Ref __iruid_2629))))) (15_to_20 (ToSet (StreamMap __iruid_2632 (StreamFilter __iruid_2633 (ToStream False (Ref __iruid_2594)) (Let __iruid_2634 (GetField gq (Ref __iruid_2633)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2634) (I32 15)) (ApplyComparisonOp LT (Ref __iruid_2634) (I32 20))))) (GetField sample_id (Ref __iruid_2632))))) (20_to_25 (ToSet (StreamMap __iruid_2635 (StreamFilter __iruid_2636 (ToStream False (Ref __iruid_2594)) (Let __iruid_2637 (GetField gq (Ref __iruid_2636)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2637) (I32 20)) (ApplyComparisonOp LT (Ref __iruid_2637) (I32 25))))) (GetField sample_id (Ref __iruid_2635))))) (25_to_30 (ToSet (StreamMap __iruid_2638 (StreamFilter __iruid_2639 (ToStream False (Ref __iruid_2594)) (Let __iruid_2640 (GetField gq (Ref __iruid_2639)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2640) (I32 25)) (ApplyComparisonOp LT (Ref __iruid_2640) (I32 30))))) (GetField sample_id (Ref __iruid_2638))))) (30_to_35 (ToSet (StreamMap __iruid_2641 (StreamFilter __iruid_2642 (ToStream False (Ref __iruid_2594)) (Let __iruid_2643 (GetField gq (Ref __iruid_2642)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2643) (I32 30)) (ApplyComparisonOp LT (Ref __iruid_2643) (I32 35))))) (GetField sample_id (Ref __iruid_2641))))) (35_to_40 (ToSet (StreamMap __iruid_2644 (StreamFilter __iruid_2645 (ToStream False (Ref __iruid_2594)) (Let __iruid_2646 (GetField gq (Ref __iruid_2645)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2646) (I32 35)) (ApplyComparisonOp LT (Ref __iruid_2646) (I32 40))))) (GetField sample_id (Ref __iruid_2644))))) (40_to_45 (ToSet (StreamMap __iruid_2647 (StreamFilter __iruid_2648 (ToStream False (Ref __iruid_2594)) (Let __iruid_2649 (GetField gq (Ref __iruid_2648)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2649) (I32 40)) (ApplyComparisonOp LT (Ref __iruid_2649) (I32 45))))) (GetField sample_id (Ref __iruid_2647))))) (45_to_50 (ToSet (StreamMap __iruid_2650 (StreamFilter __iruid_2651 (ToStream False (Ref __iruid_2594)) (Let __iruid_2652 (GetField gq (Ref __iruid_2651)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2652) (I32 45)) (ApplyComparisonOp LT (Ref __iruid_2652) (I32 50))))) (GetField sample_id (Ref __iruid_2650))))) (50_to_55 (ToSet (StreamMap __iruid_2653 (StreamFilter __iruid_2654 (ToStream False (Ref __iruid_2594)) (Let __iruid_2655 (GetField gq (Ref __iruid_2654)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2655) (I32 50)) (ApplyComparisonOp LT (Ref __iruid_2655) (I32 55))))) (GetField sample_id (Ref __iruid_2653))))) (55_to_60 (ToSet (StreamMap __iruid_2656 (StreamFilter __iruid_2657 (ToStream False (Ref __iruid_2594)) (Let __iruid_2658 (GetField gq (Ref __iruid_2657)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2658) (I32 55)) (ApplyComparisonOp LT (Ref __iruid_2658) (I32 60))))) (GetField sample_id (Ref __iruid_2656))))) (60_to_65 (ToSet (StreamMap __iruid_2659 (StreamFilter __iruid_2660 (ToStream False (Ref __iruid_2594)) (Let __iruid_2661 (GetField gq (Ref __iruid_2660)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2661) (I32 60)) (ApplyComparisonOp LT (Ref __iruid_2661) (I32 65))))) (GetField sample_id (Ref __iruid_2659))))) (65_to_70 (ToSet (StreamMap __iruid_2662 (StreamFilter __iruid_2663 (ToStream False (Ref __iruid_2594)) (Let __iruid_2664 (GetField gq (Ref __iruid_2663)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2664) (I32 65)) (ApplyComparisonOp LT (Ref __iruid_2664) (I32 70))))) (GetField sample_id (Ref __iruid_2662))))) (70_to_75 (ToSet (StreamMap __iruid_2665 (StreamFilter __iruid_2666 (ToStream False (Ref __iruid_2594)) (Let __iruid_2667 (GetField gq (Ref __iruid_2666)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2667) (I32 70)) (ApplyComparisonOp LT (Ref __iruid_2667) (I32 75))))) (GetField sample_id (Ref __iruid_2665))))) (75_to_80 (ToSet (StreamMap __iruid_2668 (StreamFilter __iruid_2669 (ToStream False (Ref __iruid_2594)) (Let __iruid_2670 (GetField gq (Ref __iruid_2669)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2670) (I32 75)) (ApplyComparisonOp LT (Ref __iruid_2670) (I32 80))))) (GetField sample_id (Ref __iruid_2668))))) (80_to_85 (ToSet (StreamMap __iruid_2671 (StreamFilter __iruid_2672 (ToStream False (Ref __iruid_2594)) (Let __iruid_2673 (GetField gq (Ref __iruid_2672)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2673) (I32 80)) (ApplyComparisonOp LT (Ref __iruid_2673) (I32 85))))) (GetField sample_id (Ref __iruid_2671))))) (85_to_90 (ToSet (StreamMap __iruid_2674 (StreamFilter __iruid_2675 (ToStream False (Ref __iruid_2594)) (Let __iruid_2676 (GetField gq (Ref __iruid_2675)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2676) (I32 85)) (ApplyComparisonOp LT (Ref __iruid_2676) (I32 90))))) (GetField sample_id (Ref __iruid_2674))))) (90_to_95 (ToSet (StreamMap __iruid_2677 (StreamFilter __iruid_2678 (ToStream False (Ref __iruid_2594)) (Let __iruid_2679 (GetField gq (Ref __iruid_2678)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_2679) (I32 90)) (ApplyComparisonOp LT (Ref __iruid_2679) (I32 95))))) (GetField sample_id (Ref __iruid_2677))))))) (samples_no_call (ToSet (StreamMap __iruid_2680 (StreamFilter __iruid_2681 (ToStream False (GetField genotypes (Ref __iruid_2592))) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2681)) (I32 -1))) (GetField sample_id (Ref __iruid_2680))))) (samples_num_alt (MakeStruct (1 (ToSet (StreamMap __iruid_2682 (StreamFilter __iruid_2683 (ToStream False (Ref __iruid_2595)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2683)) (I32 1))) (GetField sample_id (Ref __iruid_2682))))) (2 (ToSet (StreamMap __iruid_2684 (StreamFilter __iruid_2685 (ToStream False (Ref __iruid_2595)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_2685)) (I32 2))) (GetField sample_id (Ref __iruid_2684))))))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],splice_ai:Struct{delta_score:Float32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2998 (MakeStruct) (Let __iruid_2689 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt) (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt __uid_111) (Ref row))) (InsertFields (Ref __iruid_2689) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "splice_ai" "start") (splice_ai (GetField splice_ai (GetField __uid_111 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt __uid_111) (Ref row))))) (start (Apply position () Int32 (GetField locus (Ref __iruid_2689))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],topmed:Struct{AC:Int32,AF:Float64,AN:Int32,Hom:Int32,Het:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (Let n_cols (ArrayLen (GetField __cols (Ref global))) (InsertFields (Let __iruid_2999 (MakeStruct) (Let __iruid_2690 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start) (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start __uid_112) (Ref row))) (Let __iruid_2691 (GetField locus (Ref __iruid_2690)) (Let __iruid_2692 (GetField alleles (Ref __iruid_2690)) (Let __iruid_2693 (GetField locus (Ref __iruid_2690)) (Let __iruid_2694 (GetField locus (Ref __iruid_2690)) (Let __iruid_2695 (GetField locus (Ref __iruid_2690)) (InsertFields (SelectFields (locus alleles aIndex AC AF alt AN cadd clinvar codingGeneIds contig dbnsfp docId domains eigen end exac filters g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref rsid samples_ab samples_gq samples_no_call samples_num_alt sortedTranscriptConsequences splice_ai start vep) (Ref __iruid_2690)) ("locus" "alleles" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "filters" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "rsid" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "sortedTranscriptConsequences" "splice_ai" "start" "topmed" "transcriptConsequenceTerms" "transcriptIds" "utrVariantAnnotation" "variantId" "vep" "xpos" "xstart" "xstop") (topmed (GetField topmed (GetField __uid_112 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start __uid_112) (Ref row))))) (transcriptConsequenceTerms (ToSet (StreamFlatMap __iruid_2696 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_2690))) (ToStream False (GetField consequence_terms (Ref __iruid_2696)))))) (transcriptIds (ToSet (StreamMap __iruid_2697 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_2690))) (GetField transcript_id (Ref __iruid_2697))))) (utrVariantAnnotation (ToArray (StreamMap __iruid_2698 (StreamFilter __iruid_2699 (ToStream False (GetField transcript_consequences (GetField vep (Ref __iruid_2690)))) (Let __iruid_2700 (Str "5_prime_UT...") (StreamFold __iruid_2701 __iruid_2702 (ToStream False (GetField consequence_terms (Ref __iruid_2699))) (False) (ApplySpecial lor () Boolean (Ref __iruid_2701) (ApplyComparisonOp EQWithNA (Ref __iruid_2702) (Ref __iruid_2700)))))) (MakeStruct (existing_inframe_oorfs (GetField existing_inframe_oorfs (Ref __iruid_2698))) (existing_outofframe_oorfs (GetField existing_outofframe_oorfs (Ref __iruid_2698))) (existing_uorfs (GetField existing_uorfs (Ref __iruid_2698))) (five_prime_utr_variant_consequence (GetField five_prime_utr_variant_consequence (Ref __iruid_2698))) (five_prime_utr_variant_annotation (GetField five_prime_utr_variant_annotation (Ref __iruid_2698))))))) (variantId (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_2691)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_2691)))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_2692) (I32 0) (Str " File \"/h..."))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_2692) (I32 1) (Str " File \"/h...")))) (xpos (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_2703 (Apply replace () String (Apply contig () String (Ref __iruid_2693)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_2703) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_2703) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __iruid_2703) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_2703))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_2693))))) (xstart (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_2704 (Apply replace () String (Apply contig () String (Ref __iruid_2694)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_2704) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_2704) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __iruid_2704) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_2704))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_2694))))) (xstop (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_2705 (Apply replace () String (Apply contig () String (Ref __iruid_2695)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_2705) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_2705) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __iruid_2705) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_2705))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_2695)))) (Cast Int64 (Apply length () Int32 (ApplyIR indexArray () String (GetField alleles (Ref __iruid_2690)) (I32 0) (Str " File \"/h..."))))) (I64 1))))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (InsertFields (InsertFields (SelectFields (gencodeVersion) (Ref global)) None (sourceFilePath (Str "s3://seqr-...")) (genomeVersion (Str "38")) (sampleType (Str "WGS")) (hail_version (Str "0.2.57"))) None (__cols (GetField __cols (Ref global)))))) 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- FoldConstants : 13.680ms, total 1.748s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 17.259ms, total 1.766s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- Simplify : 28.256ms, total 1.794s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ForwardLets : 61.354ms, total 1.856s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 5.120ms, total 1.861s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- PruneDeadFields : 149.638ms, total 2.011s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- FoldConstants : 8.136ms, total 2.019s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 12.352ms, total 2.032s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- Simplify : 18.586ms, total 2.051s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ForwardLets : 50.458ms, total 2.101s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 5.269ms, total 2.107s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- PruneDeadFields : 136.608ms, total 2.243s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- FoldConstants : 8.549ms, total 2.252s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 12.192ms, total 2.265s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- Simplify : 12.180ms, total 2.277s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ForwardLets : 45.524ms, total 2.323s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 4.001ms, total 2.327s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize -- PruneDeadFields : 136.507ms, total 2.463s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation -- Optimize : 729.102ms, total 2.464s, tagged coverage 99.5 2022-04-01 03:25:19 root: INFO: optimize optimize: relationalLowerer, after LowerMatrixToTable: after: IR size 1594: (TableWrite "{\"writer\":{\"path\":\"s3://seqr-dp-build--prod/mt-hail-luigi/SEQR2_PROD/IUIS_PANELv1_20220321.mt\",\"overwrite\":true,\"stageLocally\":false,\"codecSpecJSONStr\":null,\"partitions\":null,\"partitionsTypeStr\":null},\"colsFieldName\":\"__cols\",\"entriesFieldName\":\"the entries! [877f12a8827e18f61222c6c8c5fb04a8]\",\"colKey\":[\"s\"]}" (TableMapGlobals (TableMapRows (TableLeftJoinRightDistinct __uid_112 (TableMapRows (TableLeftJoinRightDistinct __uid_111 (TableMapRows (TableLeftJoinRightDistinct __uid_48 (TableMapRows (TableLeftJoinRightDistinct __uid_46 (TableMapRows (TableLeftJoinRightDistinct __uid_44 (TableMapRows (TableLeftJoinRightDistinct __uid_43 (TableMapRows (TableLeftJoinRightDistinct __uid_42 (TableMapRows (TableLeftJoinRightDistinct __uid_41 (TableMapRows (TableLeftJoinRightDistinct __uid_38 (TableMapRows (TableLeftJoinRightDistinct __uid_36 (TableMapRows (TableLeftJoinRightDistinct __uid_35 (TableMapRows (TableLeftJoinRightDistinct __uid_34 (TableMapRows (TableLeftJoinRightDistinct __uid_31 (TableMapRows (TableLeftJoinRightDistinct __uid_8 (TableLeftJoinRightDistinct __uid_7 (TableLeftJoinRightDistinct __uid_6 (TableMapRows (TableLeftJoinRightDistinct __uid_5 (TableMapRows (TableLeftJoinRightDistinct __uid_4 (TableMapGlobals (TableKeyBy (locus alleles) False (TableMapRows (TableKeyBy () False (TableMapRows (TableRead Table{global:Struct{__cols:Array[Struct{s:String}]},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]}} False "{\"files\":[\"s3://seqr-dp-data--prod/vcf/prod/IUIS_PANELv1_20220321.vcf.gz\"],\"callFields\":[\"PGT\"],\"entryFloatTypeName\":\"Float64\",\"minPartitions\":500,\"rg\":\"GRCh38\",\"contigRecoding\":{},\"arrayElementsRequired\":false,\"skipInvalidLoci\":false,\"gzAsBGZ\":true,\"forceGZ\":false,\"filterAndReplace\":{},\"partitionsJSON\":null,\"name\":\"MatrixVCFReader\"}") (InsertFields (Ref row) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (a_index (I32 1)) (alleles_old (GetField alleles (Ref row))) (locus_old (GetField locus (Ref row)))))) (InsertFields (Let __iruid_4283 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (Ref row)) (GetField alleles (Ref row))) (InsertFields (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (Ref row)) None (locus (GetField locus (Ref __iruid_4283))) (alleles (GetField alleles (Ref __iruid_4283))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)))))) (InsertFields (Ref global) ("gencodeVersion" "__cols") (gencodeVersion (Str "25")))) (TableLiteral)) (InsertFields (Let __iruid_4284 (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (Ref row)) (InsertFields (Ref __iruid_4284) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN") (vep (GetField vep (GetField __uid_4 (Ref row)))) (aIndex (GetField a_index (Ref __iruid_4284))) (AC (ApplyIR indexArray () Int32 (GetField AC (GetField info (Ref __iruid_4284))) (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_4284)) (I32 1)) (Str " File \"/h..."))) (AF (ApplyIR indexArray () Float64 (GetField AF (GetField info (Ref __iruid_4284))) (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_4284)) (I32 1)) (Str " File \"/h..."))) (alt (ApplyIR indexArray () String (GetField alleles (Ref __iruid_4284)) (I32 1) (Str " File \"/h..."))) (AN (GetField AN (GetField info (Ref __iruid_4284)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],cadd:Struct{PHRED:Float32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (Ref row)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (cadd (GetField cadd (GetField __uid_5 (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],info:Struct{ALLELEID:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht\",\"name\":\"TableNativeReader\"}")) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],info:Struct{CLNSIG:Array[String]}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht\",\"name\":\"TableNativeReader\"}")) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],gold_stars:Int32}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (Let __iruid_4294 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd) (Ref row)) (Let __iruid_4295 (GetField vep (Ref __iruid_4294)) (Let __iruid_4296 (ToArray (StreamMap __iruid_4297 (ToStream False (ArraySort __iruid_4298 __iruid_4299 (StreamMap __iruid_4300 (StreamFilter __iruid_4301 (StreamMap __iruid_4302 (ToStream False (GetField transcript_consequences (Ref __iruid_4295))) (Let __iruid_4303 (GetField consequence_terms (Ref __iruid_4302)) (InsertFields (SelectFields (biotype canonical cdna_start cdna_end codons gene_id gene_symbol hgvsc hgvsp transcript_id amino_acids lof lof_filter lof_flags lof_info polyphen_prediction protein_id protein_start sift_prediction) (Ref __iruid_4302)) None (consequence_terms (ToArray (StreamFilter __iruid_4304 (ToStream False (Ref __iruid_4303)) (ApplyUnaryPrimOp Bang (ApplyIR contains () Boolean (ToSet (ToStream False (Literal Array[String] ))) (Ref __iruid_4304)))))) (domains (ToArray (StreamMap __iruid_4305 (ToStream False (GetField domains (Ref __iruid_4302))) (Apply concat () String (Apply concat () String (GetField db (Ref __iruid_4305)) (Str ":")) (GetField name (Ref __iruid_4305)))))) (major_consequence (If (ApplyComparisonOp GT (ArrayLen (Ref __iruid_4303)) (I32 0)) (ApplyIR indexArray () String (ToArray (StreamMap __iruid_4306 (ToStream False (ArraySort __iruid_4307 __iruid_4308 (StreamMap __iruid_4309 (ToStream False (GetField consequence_terms (Ref __iruid_4302))) (MakeTuple (0 1) (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (Ref __iruid_4309)) (Ref __iruid_4309))) (If (IsNA (GetTupleElement 0 (Ref __iruid_4307))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_4308))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_4307)) (GetTupleElement 0 (Ref __iruid_4308))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_4306)))) (I32 0) (Str " File \"/h...")) (NA String)))))) (ApplyComparisonOp GT (ArrayLen (GetField consequence_terms (Ref __iruid_4301))) (I32 0))) (Let __iruid_4310 (GetField major_consequence (Ref __iruid_4300)) (Let __iruid_4311 (InsertFields (Ref __iruid_4300) None (category (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (Ref __iruid_4310)) (I32 4)) (Str "lof") (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (GetField major_consequence (Ref __iruid_4300))) (I32 11)) (Str "missense") (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (GetField major_consequence (Ref __iruid_4300))) (I32 17)) (Str "synonymous") (Str "other"))))) (hgvs (If (ApplySpecial lor () Boolean (IsNA (GetField hgvsp (Ref __iruid_4300))) (ApplyIR contains () Boolean (ToSet (ToStream False (Literal Array[String] ))) (Ref __iruid_4310))) (ApplyIR indexArray () String (Apply split () Array[String] (GetField hgvsc (Ref __iruid_4300)) (Str ":")) (I32 -1) (Str " File \"/h...")) (Let __iruid_4312 (GetField hgvsp (Ref __iruid_4300)) (If (ApplySpecial lor () Boolean (Apply contains () Boolean (Ref __iruid_4312) (Str "=")) (Apply contains () Boolean (Ref __iruid_4312) (Str "%3D"))) (Let __iruid_4313 (Apply mkString () String (ToArray (StreamMap __iruid_4314 (ToStream False (Apply split () Array[String] (GetField amino_acids (Ref __iruid_4300)) (Str ""))) (ApplyIR get () String (Literal Dict[String,String] ) (Ref __iruid_4314)))) (Str "")) (Apply concat () String (Apply concat () String (Apply concat () String (Str "p.") (Ref __iruid_4313)) (Apply str () String (GetField protein_start (Ref __iruid_4300)))) (Ref __iruid_4313))) (ApplyIR indexArray () String (Apply split () Array[String] (GetField hgvsp (Ref __iruid_4300)) (Str ":")) (I32 -1) (Str " File \"/h...")))))) (major_consequence_rank (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (Ref __iruid_4310)))) (MakeTuple (0 1) (Let __iruid_4315 (ApplyComparisonOp EQ (Coalesce (GetField canonical (Ref __iruid_4311)) (I32 0)) (I32 1)) (Let __iruid_4316 (ApplyIR contains () Boolean (ToSet (ToStream False (GetField consequence_terms (Ref __iruid_4311)))) (GetField most_severe_consequence (Ref __iruid_4295))) (If (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_4311)) (Str "")) (Str "protein_co...")) (If (Ref __iruid_4316) (If (Ref __iruid_4315) (I32 1) (I32 2)) (If (Ref __iruid_4315) (I32 3) (I32 4))) (If (Ref __iruid_4316) (If (Ref __iruid_4315) (I32 5) (I32 6)) (If (Ref __iruid_4315) (I32 7) (I32 8)))))) (Ref __iruid_4311))))) (If (IsNA (GetTupleElement 0 (Ref __iruid_4298))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_4299))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_4298)) (GetTupleElement 0 (Ref __iruid_4299))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_4297)))) (Let __iruid_4317 (ToArray (StreamMap __iruid_4318 (StreamRange False (I32 0) (ArrayLen (Ref __iruid_4296)) (I32 1)) (Let __iruid_4319 (MakeTuple (0 1) (Ref __iruid_4318) (ApplyIR indexArray () Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32} (Ref __iruid_4296) (Ref __iruid_4318) (Str " File \"/h..."))) (InsertFields (GetTupleElement 1 (Ref __iruid_4319)) None (transcript_rank (GetTupleElement 0 (Ref __iruid_4319))))))) (InsertFields (Ref __iruid_4294) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig") (clinvar (MakeStruct (allele_id (GetField ALLELEID (GetField info (GetField __uid_6 (Ref row))))) (clinical_significance (Apply mkString () String (GetField CLNSIG (GetField info (GetField __uid_7 (Ref row)))) (Str ","))) (gold_stars (GetField gold_stars (GetField __uid_8 (Ref row)))))) (sortedTranscriptConsequences (Ref __iruid_4317)) (codingGeneIds (ToSet (StreamMap __iruid_4320 (StreamFilter __iruid_4321 (ToStream False (Ref __iruid_4317)) (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_4321)) (Str "")) (Str "protein_co..."))) (GetField gene_id (Ref __iruid_4320))))) (contig (Apply replace () String (Apply contig () String (GetField locus (Ref __iruid_4294))) (Str "^chr") (Str "")))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (Let __iruid_4322 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig) (Ref row)) (Let __iruid_4323 (GetField locus (Ref __iruid_4322)) (Let __iruid_4324 (GetField alleles (Ref __iruid_4322)) (InsertFields (Ref __iruid_4322) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains") (dbnsfp (GetField dbnsfp (GetField __uid_31 (Ref row)))) (docId (ApplyIR slice () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_4323)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_4323)))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_4324) (I32 0) (Str " File \"/h..."))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_4324) (I32 1) (Str " File \"/h..."))) (I32 0) (I32 512))) (domains (ToSet (StreamFlatMap __iruid_4325 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_4322))) (ToStream False (GetField domains (Ref __iruid_4325)))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],eigen:Struct{Eigen_phred:Float64}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (Let __iruid_4338 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains) (Ref row)) (InsertFields (Ref __iruid_4338) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end") (eigen (GetField eigen (GetField __uid_34 (Ref row)))) (end (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (Apply position () Int32 (GetField locus (Ref __iruid_4338))) (Apply length () Int32 (ApplyIR indexArray () String (GetField alleles (Ref __iruid_4338)) (I32 0) (Str " File \"/h...")))) (I32 1))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (Let __iruid_4342 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end) (Ref row)) (InsertFields (Ref __iruid_4342) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac") (exac (GetField exac (GetField __uid_35 (Ref row)))) (filters (GetField filters (Ref __iruid_4342))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (Let __iruid_4343 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac) (Ref row)) (InsertFields (Ref __iruid_4343) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds") (g1k (GetField g1k (GetField __uid_36 (Ref row)))) (geneIds (ToSet (StreamMap __iruid_4344 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_4343))) (GetField gene_id (Ref __iruid_4344))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],geno2mp:Struct{HPO_Count:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (StreamAgg __iruid_4345 (StreamFilter __iruid_4346 (StreamRange False (I32 0) (ArrayLen (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row))) (I32 1)) (ApplyUnaryPrimOp Bang (IsNA (ArrayRef (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)) (Ref __iruid_4346) (Str ""))))) (AggLet __iruid_4347 False (ArrayRef (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row)) (Ref __iruid_4345) (Str "")) (AggLet __iruid_4348 False (ApplyUnaryPrimOp Bang (IsNA (GetField GT (Ref __iruid_4347)))) (AggLet __iruid_4349 False (GetField AD (Ref __iruid_4347)) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds) (Ref row)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes") (geno2mp (GetField geno2mp (GetField __uid_38 (Ref row)))) (genotypes (ApplyAggOp Collect () ( (MakeStruct (num_alt (If (Ref __iruid_4348) (Apply nNonRefAlleles () Int32 (GetField GT (Ref __iruid_4347))) (I32 -1))) (gq (If (Ref __iruid_4348) (GetField GQ (Ref __iruid_4347)) (NA Int32))) (ab (Let __iruid_4350 (StreamFold __iruid_4351 __iruid_4352 (StreamFilter __iruid_4353 (ToStream False (Ref __iruid_4349)) (ApplyUnaryPrimOp Bang (IsNA (Ref __iruid_4353)))) (I32 0) (ApplyBinaryPrimOp Add (Ref __iruid_4351) (Ref __iruid_4352))) (If (ApplySpecial land () Boolean (ApplySpecial land () Boolean (Ref __iruid_4348) (ApplyComparisonOp NEQ (Ref __iruid_4350) (I32 0))) (ApplyComparisonOp GT (ArrayLen (Ref __iruid_4349)) (I32 1))) (Cast Float64 (ApplyBinaryPrimOp FloatingPointDivide (ApplyIR indexArray () Int32 (GetField AD (Ref __iruid_4347)) (I32 1) (Str " File \"/h...")) (Ref __iruid_4350))) (NA Float64)))) (dp (If (Ref __iruid_4348) (Cast Float64 (ApplySpecial min_ignore_missing () Int32 (GetField DP (Ref __iruid_4347)) (I32 32000))) (NA Float64))) (ad (If (Ref __iruid_4348) (Apply format () String (Str "%s") (MakeTuple (0) (GetField AD (Ref __iruid_4347)))) (NA String))) (pl (If (Ref __iruid_4348) (Apply format () String (Str "%s") (MakeTuple (0) (GetField PL (Ref __iruid_4347)))) (NA String))) (sample_id (GetField s (ArrayRef (GetField __cols (Ref global)) (Ref __iruid_4345) (Str ""))))))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],gnomad_exome_coverage:Float64}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (Ref row)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_exome_coverage (GetField gnomad_exome_coverage (GetField __uid_41 (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (Ref row)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_exomes (GetField gnomad_exomes (GetField __uid_42 (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],gnomad_genome_coverage:Float32}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (Ref row)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_genome_coverage (GetField gnomad_genome_coverage (GetField __uid_43 (Ref row)))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (Let __iruid_4354 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage) (Ref row)) (InsertFields (Ref __iruid_4354) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript") (gnomad_genomes (GetField gnomad_genomes (GetField __uid_44 (Ref row)))) (mainTranscript (If (ApplyComparisonOp EQ (ArrayLen (GetField sortedTranscriptConsequences (Ref __iruid_4354))) (I32 0)) (Literal Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String} ) (Let __iruid_4355 (ApplyIR indexArray () Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32} (GetField sortedTranscriptConsequences (Ref __iruid_4354)) (I32 0) (Str " File \"/h...")) (InsertFields (SelectFields (biotype canonical category cdna_start cdna_end codons gene_id gene_symbol hgvs hgvsc major_consequence major_consequence_rank transcript_id amino_acids domains hgvsp lof lof_flags lof_filter lof_info polyphen_prediction protein_id sift_prediction) (Ref __iruid_4355)) ("biotype" "canonical" "category" "cdna_start" "cdna_end" "codons" "gene_id" "gene_symbol" "hgvs" "hgvsc" "major_consequence" "major_consequence_rank" "transcript_id" "amino_acids" "domains" "hgvsp" "lof" "lof_flags" "lof_filter" "lof_info" "polyphen_prediction" "protein_id" "sift_prediction") (domains (Apply mkString () String (ToSet (ToStream False (GetField domains (Ref __iruid_4355)))) (Str ","))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],mpc:Struct{MPC:String}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (Let __iruid_4356 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript) (Ref row)) (Let __iruid_4357 (GetField alleles_old (Ref __iruid_4356)) (Let __iruid_4358 (GetField locus_old (Ref __iruid_4356)) (InsertFields (Ref __iruid_4356) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos") (mpc (GetField mpc (GetField __uid_46 (Ref row)))) (originalAltAlleles (ToArray (StreamMap __iruid_4359 (ToStream False (ApplyIR sliceRight () Array[String] (Ref __iruid_4357) (I32 1))) (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply contig () String (Ref __iruid_4358)) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_4358)))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_4357) (I32 0) (Str " File \"/h..."))) (Str "-")) (Ref __iruid_4359))))) (pos (Apply position () Int32 (GetField locus (Ref __iruid_4356)))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],primate_ai:Struct{score:Float64}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (Let __iruid_4363 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos) (Ref row)) (Let __iruid_4364 (GetField genotypes (Ref __iruid_4363)) (Let __iruid_4365 (GetField genotypes (Ref __iruid_4363)) (Let __iruid_4366 (GetField genotypes (Ref __iruid_4363)) (InsertFields (Ref __iruid_4363) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt") (primate_ai (GetField primate_ai (GetField __uid_48 (Ref row)))) (ref (ApplyIR indexArray () String (GetField alleles (Ref __iruid_4363)) (I32 0) (Str " File \"/h..."))) (rsid (GetField rsid (Ref __iruid_4363))) (samples_ab (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_4367 (StreamFilter __iruid_4368 (ToStream False (Ref __iruid_4364)) (Let __iruid_4369 (GetField ab (Ref __iruid_4368)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4368)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4369) (F64 100.0)) (F64 0.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4369) (F64 100.0)) (F64 5.0))))) (GetField sample_id (Ref __iruid_4367))))) (5_to_10 (ToSet (StreamMap __iruid_4370 (StreamFilter __iruid_4371 (ToStream False (Ref __iruid_4364)) (Let __iruid_4372 (GetField ab (Ref __iruid_4371)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4371)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4372) (F64 100.0)) (F64 5.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4372) (F64 100.0)) (F64 10.0))))) (GetField sample_id (Ref __iruid_4370))))) (10_to_15 (ToSet (StreamMap __iruid_4373 (StreamFilter __iruid_4374 (ToStream False (Ref __iruid_4364)) (Let __iruid_4375 (GetField ab (Ref __iruid_4374)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4374)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4375) (F64 100.0)) (F64 10.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4375) (F64 100.0)) (F64 15.0))))) (GetField sample_id (Ref __iruid_4373))))) (15_to_20 (ToSet (StreamMap __iruid_4376 (StreamFilter __iruid_4377 (ToStream False (Ref __iruid_4364)) (Let __iruid_4378 (GetField ab (Ref __iruid_4377)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4377)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4378) (F64 100.0)) (F64 15.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4378) (F64 100.0)) (F64 20.0))))) (GetField sample_id (Ref __iruid_4376))))) (20_to_25 (ToSet (StreamMap __iruid_4379 (StreamFilter __iruid_4380 (ToStream False (Ref __iruid_4364)) (Let __iruid_4381 (GetField ab (Ref __iruid_4380)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4380)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4381) (F64 100.0)) (F64 20.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4381) (F64 100.0)) (F64 25.0))))) (GetField sample_id (Ref __iruid_4379))))) (25_to_30 (ToSet (StreamMap __iruid_4382 (StreamFilter __iruid_4383 (ToStream False (Ref __iruid_4364)) (Let __iruid_4384 (GetField ab (Ref __iruid_4383)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4383)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4384) (F64 100.0)) (F64 25.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4384) (F64 100.0)) (F64 30.0))))) (GetField sample_id (Ref __iruid_4382))))) (30_to_35 (ToSet (StreamMap __iruid_4385 (StreamFilter __iruid_4386 (ToStream False (Ref __iruid_4364)) (Let __iruid_4387 (GetField ab (Ref __iruid_4386)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4386)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4387) (F64 100.0)) (F64 30.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4387) (F64 100.0)) (F64 35.0))))) (GetField sample_id (Ref __iruid_4385))))) (35_to_40 (ToSet (StreamMap __iruid_4388 (StreamFilter __iruid_4389 (ToStream False (Ref __iruid_4364)) (Let __iruid_4390 (GetField ab (Ref __iruid_4389)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4389)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4390) (F64 100.0)) (F64 35.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4390) (F64 100.0)) (F64 40.0))))) (GetField sample_id (Ref __iruid_4388))))) (40_to_45 (ToSet (StreamMap __iruid_4391 (StreamFilter __iruid_4392 (ToStream False (Ref __iruid_4364)) (Let __iruid_4393 (GetField ab (Ref __iruid_4392)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4392)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4393) (F64 100.0)) (F64 40.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4393) (F64 100.0)) (F64 45.0))))) (GetField sample_id (Ref __iruid_4391))))))) (samples_gq (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_4394 (StreamFilter __iruid_4395 (ToStream False (Ref __iruid_4365)) (Let __iruid_4396 (GetField gq (Ref __iruid_4395)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4396) (I32 0)) (ApplyComparisonOp LT (Ref __iruid_4396) (I32 5))))) (GetField sample_id (Ref __iruid_4394))))) (5_to_10 (ToSet (StreamMap __iruid_4397 (StreamFilter __iruid_4398 (ToStream False (Ref __iruid_4365)) (Let __iruid_4399 (GetField gq (Ref __iruid_4398)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4399) (I32 5)) (ApplyComparisonOp LT (Ref __iruid_4399) (I32 10))))) (GetField sample_id (Ref __iruid_4397))))) (10_to_15 (ToSet (StreamMap __iruid_4400 (StreamFilter __iruid_4401 (ToStream False (Ref __iruid_4365)) (Let __iruid_4402 (GetField gq (Ref __iruid_4401)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4402) (I32 10)) (ApplyComparisonOp LT (Ref __iruid_4402) (I32 15))))) (GetField sample_id (Ref __iruid_4400))))) (15_to_20 (ToSet (StreamMap __iruid_4403 (StreamFilter __iruid_4404 (ToStream False (Ref __iruid_4365)) (Let __iruid_4405 (GetField gq (Ref __iruid_4404)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4405) (I32 15)) (ApplyComparisonOp LT (Ref __iruid_4405) (I32 20))))) (GetField sample_id (Ref __iruid_4403))))) (20_to_25 (ToSet (StreamMap __iruid_4406 (StreamFilter __iruid_4407 (ToStream False (Ref __iruid_4365)) (Let __iruid_4408 (GetField gq (Ref __iruid_4407)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4408) (I32 20)) (ApplyComparisonOp LT (Ref __iruid_4408) (I32 25))))) (GetField sample_id (Ref __iruid_4406))))) (25_to_30 (ToSet (StreamMap __iruid_4409 (StreamFilter __iruid_4410 (ToStream False (Ref __iruid_4365)) (Let __iruid_4411 (GetField gq (Ref __iruid_4410)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4411) (I32 25)) (ApplyComparisonOp LT (Ref __iruid_4411) (I32 30))))) (GetField sample_id (Ref __iruid_4409))))) (30_to_35 (ToSet (StreamMap __iruid_4412 (StreamFilter __iruid_4413 (ToStream False (Ref __iruid_4365)) (Let __iruid_4414 (GetField gq (Ref __iruid_4413)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4414) (I32 30)) (ApplyComparisonOp LT (Ref __iruid_4414) (I32 35))))) (GetField sample_id (Ref __iruid_4412))))) (35_to_40 (ToSet (StreamMap __iruid_4415 (StreamFilter __iruid_4416 (ToStream False (Ref __iruid_4365)) (Let __iruid_4417 (GetField gq (Ref __iruid_4416)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4417) (I32 35)) (ApplyComparisonOp LT (Ref __iruid_4417) (I32 40))))) (GetField sample_id (Ref __iruid_4415))))) (40_to_45 (ToSet (StreamMap __iruid_4418 (StreamFilter __iruid_4419 (ToStream False (Ref __iruid_4365)) (Let __iruid_4420 (GetField gq (Ref __iruid_4419)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4420) (I32 40)) (ApplyComparisonOp LT (Ref __iruid_4420) (I32 45))))) (GetField sample_id (Ref __iruid_4418))))) (45_to_50 (ToSet (StreamMap __iruid_4421 (StreamFilter __iruid_4422 (ToStream False (Ref __iruid_4365)) (Let __iruid_4423 (GetField gq (Ref __iruid_4422)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4423) (I32 45)) (ApplyComparisonOp LT (Ref __iruid_4423) (I32 50))))) (GetField sample_id (Ref __iruid_4421))))) (50_to_55 (ToSet (StreamMap __iruid_4424 (StreamFilter __iruid_4425 (ToStream False (Ref __iruid_4365)) (Let __iruid_4426 (GetField gq (Ref __iruid_4425)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4426) (I32 50)) (ApplyComparisonOp LT (Ref __iruid_4426) (I32 55))))) (GetField sample_id (Ref __iruid_4424))))) (55_to_60 (ToSet (StreamMap __iruid_4427 (StreamFilter __iruid_4428 (ToStream False (Ref __iruid_4365)) (Let __iruid_4429 (GetField gq (Ref __iruid_4428)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4429) (I32 55)) (ApplyComparisonOp LT (Ref __iruid_4429) (I32 60))))) (GetField sample_id (Ref __iruid_4427))))) (60_to_65 (ToSet (StreamMap __iruid_4430 (StreamFilter __iruid_4431 (ToStream False (Ref __iruid_4365)) (Let __iruid_4432 (GetField gq (Ref __iruid_4431)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4432) (I32 60)) (ApplyComparisonOp LT (Ref __iruid_4432) (I32 65))))) (GetField sample_id (Ref __iruid_4430))))) (65_to_70 (ToSet (StreamMap __iruid_4433 (StreamFilter __iruid_4434 (ToStream False (Ref __iruid_4365)) (Let __iruid_4435 (GetField gq (Ref __iruid_4434)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4435) (I32 65)) (ApplyComparisonOp LT (Ref __iruid_4435) (I32 70))))) (GetField sample_id (Ref __iruid_4433))))) (70_to_75 (ToSet (StreamMap __iruid_4436 (StreamFilter __iruid_4437 (ToStream False (Ref __iruid_4365)) (Let __iruid_4438 (GetField gq (Ref __iruid_4437)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4438) (I32 70)) (ApplyComparisonOp LT (Ref __iruid_4438) (I32 75))))) (GetField sample_id (Ref __iruid_4436))))) (75_to_80 (ToSet (StreamMap __iruid_4439 (StreamFilter __iruid_4440 (ToStream False (Ref __iruid_4365)) (Let __iruid_4441 (GetField gq (Ref __iruid_4440)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4441) (I32 75)) (ApplyComparisonOp LT (Ref __iruid_4441) (I32 80))))) (GetField sample_id (Ref __iruid_4439))))) (80_to_85 (ToSet (StreamMap __iruid_4442 (StreamFilter __iruid_4443 (ToStream False (Ref __iruid_4365)) (Let __iruid_4444 (GetField gq (Ref __iruid_4443)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4444) (I32 80)) (ApplyComparisonOp LT (Ref __iruid_4444) (I32 85))))) (GetField sample_id (Ref __iruid_4442))))) (85_to_90 (ToSet (StreamMap __iruid_4445 (StreamFilter __iruid_4446 (ToStream False (Ref __iruid_4365)) (Let __iruid_4447 (GetField gq (Ref __iruid_4446)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4447) (I32 85)) (ApplyComparisonOp LT (Ref __iruid_4447) (I32 90))))) (GetField sample_id (Ref __iruid_4445))))) (90_to_95 (ToSet (StreamMap __iruid_4448 (StreamFilter __iruid_4449 (ToStream False (Ref __iruid_4365)) (Let __iruid_4450 (GetField gq (Ref __iruid_4449)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4450) (I32 90)) (ApplyComparisonOp LT (Ref __iruid_4450) (I32 95))))) (GetField sample_id (Ref __iruid_4448))))))) (samples_no_call (ToSet (StreamMap __iruid_4451 (StreamFilter __iruid_4452 (ToStream False (GetField genotypes (Ref __iruid_4363))) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4452)) (I32 -1))) (GetField sample_id (Ref __iruid_4451))))) (samples_num_alt (MakeStruct (1 (ToSet (StreamMap __iruid_4453 (StreamFilter __iruid_4454 (ToStream False (Ref __iruid_4366)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4454)) (I32 1))) (GetField sample_id (Ref __iruid_4453))))) (2 (ToSet (StreamMap __iruid_4455 (StreamFilter __iruid_4456 (ToStream False (Ref __iruid_4366)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4456)) (I32 2))) (GetField sample_id (Ref __iruid_4455)))))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],splice_ai:Struct{delta_score:Float32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (Let __iruid_4460 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt) (Ref row)) (InsertFields (Ref __iruid_4460) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "splice_ai" "start") (splice_ai (GetField splice_ai (GetField __uid_111 (Ref row)))) (start (Apply position () Int32 (GetField locus (Ref __iruid_4460)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row))))) (TableRead Table{global:Struct{},key:[locus,alleles],row:Struct{locus:Locus(GRCh38),alleles:Array[String],topmed:Struct{AC:Int32,AF:Float64,AN:Int32,Hom:Int32,Het:Int32}}} False "{\"path\":\"s3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht\",\"name\":\"TableNativeReader\"}")) (InsertFields (Let __iruid_4461 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start) (Ref row)) (Let __iruid_4462 (GetField locus (Ref __iruid_4461)) (Let __iruid_4463 (GetField alleles (Ref __iruid_4461)) (Let __iruid_4464 (GetField locus (Ref __iruid_4461)) (Let __iruid_4465 (GetField locus (Ref __iruid_4461)) (Let __iruid_4466 (GetField locus (Ref __iruid_4461)) (InsertFields (SelectFields (locus alleles aIndex AC AF alt AN cadd clinvar codingGeneIds contig dbnsfp docId domains eigen end exac filters g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref rsid samples_ab samples_gq samples_no_call samples_num_alt sortedTranscriptConsequences splice_ai start vep) (Ref __iruid_4461)) ("locus" "alleles" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "filters" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "rsid" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "sortedTranscriptConsequences" "splice_ai" "start" "topmed" "transcriptConsequenceTerms" "transcriptIds" "utrVariantAnnotation" "variantId" "vep" "xpos" "xstart" "xstop") (topmed (GetField topmed (GetField __uid_112 (Ref row)))) (transcriptConsequenceTerms (ToSet (StreamFlatMap __iruid_4467 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_4461))) (ToStream False (GetField consequence_terms (Ref __iruid_4467)))))) (transcriptIds (ToSet (StreamMap __iruid_4468 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_4461))) (GetField transcript_id (Ref __iruid_4468))))) (utrVariantAnnotation (ToArray (StreamMap __iruid_4469 (StreamFilter __iruid_4470 (ToStream False (GetField transcript_consequences (GetField vep (Ref __iruid_4461)))) (Let __iruid_4471 (Str "5_prime_UT...") (StreamFold __iruid_4472 __iruid_4473 (ToStream False (GetField consequence_terms (Ref __iruid_4470))) (False) (ApplySpecial lor () Boolean (Ref __iruid_4472) (ApplyComparisonOp EQWithNA (Ref __iruid_4473) (Ref __iruid_4471)))))) (MakeStruct (existing_inframe_oorfs (GetField existing_inframe_oorfs (Ref __iruid_4469))) (existing_outofframe_oorfs (GetField existing_outofframe_oorfs (Ref __iruid_4469))) (existing_uorfs (GetField existing_uorfs (Ref __iruid_4469))) (five_prime_utr_variant_consequence (GetField five_prime_utr_variant_consequence (Ref __iruid_4469))) (five_prime_utr_variant_annotation (GetField five_prime_utr_variant_annotation (Ref __iruid_4469))))))) (variantId (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_4462)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_4462)))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_4463) (I32 0) (Str " File \"/h..."))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_4463) (I32 1) (Str " File \"/h...")))) (xpos (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_4474 (Apply replace () String (Apply contig () String (Ref __iruid_4464)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_4474) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_4474) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __iruid_4474) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_4474))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_4464))))) (xstart (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_4475 (Apply replace () String (Apply contig () String (Ref __iruid_4465)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_4475) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_4475) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __iruid_4475) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_4475))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_4465))))) (xstop (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_4476 (Apply replace () String (Apply contig () String (Ref __iruid_4466)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_4476) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_4476) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __iruid_4476) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_4476))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_4466)))) (Cast Int64 (Apply length () Int32 (ApplyIR indexArray () String (GetField alleles (Ref __iruid_4461)) (I32 0) (Str " File \"/h..."))))) (I64 1)))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (Ref row))))) (InsertFields (Ref global) ("gencodeVersion" "sourceFilePath" "genomeVersion" "sampleType" "hail_version" "__cols") (sourceFilePath (Str "s3://seqr-...")) (genomeVersion (Str "38")) (sampleType (Str "WGS")) (hail_version (Str "0.2.57"))))) 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- LoweringTransformation : 771.606ms, total 2.483s, tagged coverage 94.0 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable -- Verify : 0.588ms, total 2.484s 2022-04-01 03:25:19 root: INFO: Timer: Time taken for optimize: relationalLowerer, after LowerMatrixToTable : 773.349ms, total 2.484s, tagged coverage 94.0 2022-04-01 03:25:19 root: INFO: Timer: Time taken for InterpretNonCompilable -- Verify : 0.716ms, total 2.496s 2022-04-01 03:25:19 root: INFO: interpreting non compilable node: TableWrite 2022-04-01 03:25:19 SparkContext: INFO: Starting job: runJob at ContextRDD.scala:228 2022-04-01 03:25:19 DAGScheduler: INFO: Got job 2 (runJob at ContextRDD.scala:228) with 500 output partitions 2022-04-01 03:25:19 DAGScheduler: INFO: Final stage: ResultStage 2 (runJob at ContextRDD.scala:228) 2022-04-01 03:25:19 DAGScheduler: INFO: Parents of final stage: List() 2022-04-01 03:25:19 DAGScheduler: INFO: Missing parents: List() 2022-04-01 03:25:19 DAGScheduler: INFO: Submitting ResultStage 2 (GenericTableValueRDD[27] at RDD at GenericTableValue.scala:83), which has no missing parents 2022-04-01 03:25:20 MemoryStore: INFO: Block broadcast_7 stored as values in memory (estimated size 145.6 KB, free 5.6 GB) 2022-04-01 03:25:20 MemoryStore: INFO: Block broadcast_7_piece0 stored as bytes in memory (estimated size 49.5 KB, free 5.6 GB) 2022-04-01 03:25:20 BlockManagerInfo: INFO: Added broadcast_7_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 49.5 KB, free: 5.6 GB) 2022-04-01 03:25:20 SparkContext: INFO: Created broadcast 7 from broadcast at DAGScheduler.scala:1280 2022-04-01 03:25:20 DAGScheduler: INFO: Submitting 500 missing tasks from ResultStage 2 (GenericTableValueRDD[27] at RDD at GenericTableValue.scala:83) (first 15 tasks are for partitions Vector(0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)) 2022-04-01 03:25:20 YarnScheduler: INFO: Adding task set 2.0 with 500 tasks 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 0.0 in stage 2.0 (TID 512, ip-172-23-70-80.ec2.internal, executor 2, partition 0, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 1.0 in stage 2.0 (TID 513, ip-172-23-75-58.ec2.internal, executor 1, partition 1, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 2.0 in stage 2.0 (TID 514, ip-172-23-70-80.ec2.internal, executor 2, partition 2, PROCESS_LOCAL, 8160 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 3.0 in stage 2.0 (TID 515, ip-172-23-75-58.ec2.internal, executor 1, partition 3, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 4.0 in stage 2.0 (TID 516, ip-172-23-70-80.ec2.internal, executor 2, partition 4, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 5.0 in stage 2.0 (TID 517, ip-172-23-75-58.ec2.internal, executor 1, partition 5, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 6.0 in stage 2.0 (TID 518, ip-172-23-70-80.ec2.internal, executor 2, partition 6, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 7.0 in stage 2.0 (TID 519, ip-172-23-75-58.ec2.internal, executor 1, partition 7, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 8.0 in stage 2.0 (TID 520, ip-172-23-70-80.ec2.internal, executor 2, partition 8, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 9.0 in stage 2.0 (TID 521, ip-172-23-75-58.ec2.internal, executor 1, partition 9, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 10.0 in stage 2.0 (TID 522, ip-172-23-70-80.ec2.internal, executor 2, partition 10, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 11.0 in stage 2.0 (TID 523, ip-172-23-75-58.ec2.internal, executor 1, partition 11, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 12.0 in stage 2.0 (TID 524, ip-172-23-70-80.ec2.internal, executor 2, partition 12, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 13.0 in stage 2.0 (TID 525, ip-172-23-75-58.ec2.internal, executor 1, partition 13, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 14.0 in stage 2.0 (TID 526, ip-172-23-70-80.ec2.internal, executor 2, partition 14, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 15.0 in stage 2.0 (TID 527, ip-172-23-75-58.ec2.internal, executor 1, partition 15, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 16.0 in stage 2.0 (TID 528, ip-172-23-70-80.ec2.internal, executor 2, partition 16, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 17.0 in stage 2.0 (TID 529, ip-172-23-75-58.ec2.internal, executor 1, partition 17, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 18.0 in stage 2.0 (TID 530, ip-172-23-70-80.ec2.internal, executor 2, partition 18, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 19.0 in stage 2.0 (TID 531, ip-172-23-75-58.ec2.internal, executor 1, partition 19, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 20.0 in stage 2.0 (TID 532, ip-172-23-70-80.ec2.internal, executor 2, partition 20, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 21.0 in stage 2.0 (TID 533, ip-172-23-75-58.ec2.internal, executor 1, partition 21, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 22.0 in stage 2.0 (TID 534, ip-172-23-70-80.ec2.internal, executor 2, partition 22, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 23.0 in stage 2.0 (TID 535, ip-172-23-75-58.ec2.internal, executor 1, partition 23, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 24.0 in stage 2.0 (TID 536, ip-172-23-70-80.ec2.internal, executor 2, partition 24, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 25.0 in stage 2.0 (TID 537, ip-172-23-75-58.ec2.internal, executor 1, partition 25, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 26.0 in stage 2.0 (TID 538, ip-172-23-70-80.ec2.internal, executor 2, partition 26, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 27.0 in stage 2.0 (TID 539, ip-172-23-75-58.ec2.internal, executor 1, partition 27, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 28.0 in stage 2.0 (TID 540, ip-172-23-70-80.ec2.internal, executor 2, partition 28, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 29.0 in stage 2.0 (TID 541, ip-172-23-75-58.ec2.internal, executor 1, partition 29, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 30.0 in stage 2.0 (TID 542, ip-172-23-70-80.ec2.internal, executor 2, partition 30, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 31.0 in stage 2.0 (TID 543, ip-172-23-75-58.ec2.internal, executor 1, partition 31, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 32.0 in stage 2.0 (TID 544, ip-172-23-70-80.ec2.internal, executor 2, partition 32, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 33.0 in stage 2.0 (TID 545, ip-172-23-75-58.ec2.internal, executor 1, partition 33, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 34.0 in stage 2.0 (TID 546, ip-172-23-70-80.ec2.internal, executor 2, partition 34, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 35.0 in stage 2.0 (TID 547, ip-172-23-75-58.ec2.internal, executor 1, partition 35, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 36.0 in stage 2.0 (TID 548, ip-172-23-70-80.ec2.internal, executor 2, partition 36, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 37.0 in stage 2.0 (TID 549, ip-172-23-75-58.ec2.internal, executor 1, partition 37, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 38.0 in stage 2.0 (TID 550, ip-172-23-70-80.ec2.internal, executor 2, partition 38, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 39.0 in stage 2.0 (TID 551, ip-172-23-75-58.ec2.internal, executor 1, partition 39, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 40.0 in stage 2.0 (TID 552, ip-172-23-70-80.ec2.internal, executor 2, partition 40, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 41.0 in stage 2.0 (TID 553, ip-172-23-75-58.ec2.internal, executor 1, partition 41, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 42.0 in stage 2.0 (TID 554, ip-172-23-70-80.ec2.internal, executor 2, partition 42, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 43.0 in stage 2.0 (TID 555, ip-172-23-75-58.ec2.internal, executor 1, partition 43, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 44.0 in stage 2.0 (TID 556, ip-172-23-70-80.ec2.internal, executor 2, partition 44, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 45.0 in stage 2.0 (TID 557, ip-172-23-75-58.ec2.internal, executor 1, partition 45, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 46.0 in stage 2.0 (TID 558, ip-172-23-70-80.ec2.internal, executor 2, partition 46, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 47.0 in stage 2.0 (TID 559, ip-172-23-75-58.ec2.internal, executor 1, partition 47, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 48.0 in stage 2.0 (TID 560, ip-172-23-70-80.ec2.internal, executor 2, partition 48, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 49.0 in stage 2.0 (TID 561, ip-172-23-75-58.ec2.internal, executor 1, partition 49, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 50.0 in stage 2.0 (TID 562, ip-172-23-70-80.ec2.internal, executor 2, partition 50, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 51.0 in stage 2.0 (TID 563, ip-172-23-75-58.ec2.internal, executor 1, partition 51, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 52.0 in stage 2.0 (TID 564, ip-172-23-70-80.ec2.internal, executor 2, partition 52, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 53.0 in stage 2.0 (TID 565, ip-172-23-75-58.ec2.internal, executor 1, partition 53, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 54.0 in stage 2.0 (TID 566, ip-172-23-70-80.ec2.internal, executor 2, partition 54, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 55.0 in stage 2.0 (TID 567, ip-172-23-75-58.ec2.internal, executor 1, partition 55, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 56.0 in stage 2.0 (TID 568, ip-172-23-70-80.ec2.internal, executor 2, partition 56, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 57.0 in stage 2.0 (TID 569, ip-172-23-75-58.ec2.internal, executor 1, partition 57, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 58.0 in stage 2.0 (TID 570, ip-172-23-70-80.ec2.internal, executor 2, partition 58, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 59.0 in stage 2.0 (TID 571, ip-172-23-75-58.ec2.internal, executor 1, partition 59, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 60.0 in stage 2.0 (TID 572, ip-172-23-70-80.ec2.internal, executor 2, partition 60, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 61.0 in stage 2.0 (TID 573, ip-172-23-75-58.ec2.internal, executor 1, partition 61, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 62.0 in stage 2.0 (TID 574, ip-172-23-70-80.ec2.internal, executor 2, partition 62, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 63.0 in stage 2.0 (TID 575, ip-172-23-75-58.ec2.internal, executor 1, partition 63, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 64.0 in stage 2.0 (TID 576, ip-172-23-70-80.ec2.internal, executor 2, partition 64, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 65.0 in stage 2.0 (TID 577, ip-172-23-75-58.ec2.internal, executor 1, partition 65, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 66.0 in stage 2.0 (TID 578, ip-172-23-70-80.ec2.internal, executor 2, partition 66, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 67.0 in stage 2.0 (TID 579, ip-172-23-75-58.ec2.internal, executor 1, partition 67, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 68.0 in stage 2.0 (TID 580, ip-172-23-70-80.ec2.internal, executor 2, partition 68, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 69.0 in stage 2.0 (TID 581, ip-172-23-75-58.ec2.internal, executor 1, partition 69, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 70.0 in stage 2.0 (TID 582, ip-172-23-70-80.ec2.internal, executor 2, partition 70, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 71.0 in stage 2.0 (TID 583, ip-172-23-75-58.ec2.internal, executor 1, partition 71, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 72.0 in stage 2.0 (TID 584, ip-172-23-70-80.ec2.internal, executor 2, partition 72, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 73.0 in stage 2.0 (TID 585, ip-172-23-75-58.ec2.internal, executor 1, partition 73, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 74.0 in stage 2.0 (TID 586, ip-172-23-70-80.ec2.internal, executor 2, partition 74, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 75.0 in stage 2.0 (TID 587, ip-172-23-75-58.ec2.internal, executor 1, partition 75, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 76.0 in stage 2.0 (TID 588, ip-172-23-70-80.ec2.internal, executor 2, partition 76, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 77.0 in stage 2.0 (TID 589, ip-172-23-75-58.ec2.internal, executor 1, partition 77, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 78.0 in stage 2.0 (TID 590, ip-172-23-70-80.ec2.internal, executor 2, partition 78, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 79.0 in stage 2.0 (TID 591, ip-172-23-75-58.ec2.internal, executor 1, partition 79, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 80.0 in stage 2.0 (TID 592, ip-172-23-70-80.ec2.internal, executor 2, partition 80, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 81.0 in stage 2.0 (TID 593, ip-172-23-75-58.ec2.internal, executor 1, partition 81, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 82.0 in stage 2.0 (TID 594, ip-172-23-70-80.ec2.internal, executor 2, partition 82, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 83.0 in stage 2.0 (TID 595, ip-172-23-75-58.ec2.internal, executor 1, partition 83, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 84.0 in stage 2.0 (TID 596, ip-172-23-70-80.ec2.internal, executor 2, partition 84, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 85.0 in stage 2.0 (TID 597, ip-172-23-75-58.ec2.internal, executor 1, partition 85, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 86.0 in stage 2.0 (TID 598, ip-172-23-70-80.ec2.internal, executor 2, partition 86, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 87.0 in stage 2.0 (TID 599, ip-172-23-75-58.ec2.internal, executor 1, partition 87, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 88.0 in stage 2.0 (TID 600, ip-172-23-70-80.ec2.internal, executor 2, partition 88, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 89.0 in stage 2.0 (TID 601, ip-172-23-75-58.ec2.internal, executor 1, partition 89, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 90.0 in stage 2.0 (TID 602, ip-172-23-70-80.ec2.internal, executor 2, partition 90, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 91.0 in stage 2.0 (TID 603, ip-172-23-75-58.ec2.internal, executor 1, partition 91, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 92.0 in stage 2.0 (TID 604, ip-172-23-70-80.ec2.internal, executor 2, partition 92, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 93.0 in stage 2.0 (TID 605, ip-172-23-75-58.ec2.internal, executor 1, partition 93, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 94.0 in stage 2.0 (TID 606, ip-172-23-70-80.ec2.internal, executor 2, partition 94, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 95.0 in stage 2.0 (TID 607, ip-172-23-75-58.ec2.internal, executor 1, partition 95, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 BlockManagerInfo: INFO: Added broadcast_7_piece0 in memory on ip-172-23-70-80.ec2.internal:37501 (size: 49.5 KB, free: 181.7 GB) 2022-04-01 03:25:20 BlockManagerInfo: INFO: Added broadcast_7_piece0 in memory on ip-172-23-75-58.ec2.internal:40133 (size: 49.5 KB, free: 181.7 GB) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 96.0 in stage 2.0 (TID 608, ip-172-23-70-80.ec2.internal, executor 2, partition 96, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 82.0 in stage 2.0 (TID 594) in 75 ms on ip-172-23-70-80.ec2.internal (executor 2) (1/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 78.0 in stage 2.0 (TID 590) in 76 ms on ip-172-23-70-80.ec2.internal (executor 2) (2/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 97.0 in stage 2.0 (TID 609, ip-172-23-70-80.ec2.internal, executor 2, partition 97, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 98.0 in stage 2.0 (TID 610, ip-172-23-70-80.ec2.internal, executor 2, partition 98, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 76.0 in stage 2.0 (TID 588) in 79 ms on ip-172-23-70-80.ec2.internal (executor 2) (3/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 99.0 in stage 2.0 (TID 611, ip-172-23-70-80.ec2.internal, executor 2, partition 99, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 94.0 in stage 2.0 (TID 606) in 74 ms on ip-172-23-70-80.ec2.internal (executor 2) (4/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 100.0 in stage 2.0 (TID 612, ip-172-23-70-80.ec2.internal, executor 2, partition 100, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 28.0 in stage 2.0 (TID 540) in 87 ms on ip-172-23-70-80.ec2.internal (executor 2) (5/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 101.0 in stage 2.0 (TID 613, ip-172-23-70-80.ec2.internal, executor 2, partition 101, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 50.0 in stage 2.0 (TID 562) in 84 ms on ip-172-23-70-80.ec2.internal (executor 2) (6/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 102.0 in stage 2.0 (TID 614, ip-172-23-70-80.ec2.internal, executor 2, partition 102, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 86.0 in stage 2.0 (TID 598) in 78 ms on ip-172-23-70-80.ec2.internal (executor 2) (7/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 103.0 in stage 2.0 (TID 615, ip-172-23-70-80.ec2.internal, executor 2, partition 103, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 26.0 in stage 2.0 (TID 538) in 89 ms on ip-172-23-70-80.ec2.internal (executor 2) (8/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 104.0 in stage 2.0 (TID 616, ip-172-23-70-80.ec2.internal, executor 2, partition 104, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 88.0 in stage 2.0 (TID 600) in 80 ms on ip-172-23-70-80.ec2.internal (executor 2) (9/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 105.0 in stage 2.0 (TID 617, ip-172-23-70-80.ec2.internal, executor 2, partition 105, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 68.0 in stage 2.0 (TID 580) in 86 ms on ip-172-23-70-80.ec2.internal (executor 2) (10/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 106.0 in stage 2.0 (TID 618, ip-172-23-70-80.ec2.internal, executor 2, partition 106, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 52.0 in stage 2.0 (TID 564) in 90 ms on ip-172-23-70-80.ec2.internal (executor 2) (11/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 107.0 in stage 2.0 (TID 619, ip-172-23-70-80.ec2.internal, executor 2, partition 107, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 80.0 in stage 2.0 (TID 592) in 87 ms on ip-172-23-70-80.ec2.internal (executor 2) (12/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 108.0 in stage 2.0 (TID 620, ip-172-23-70-80.ec2.internal, executor 2, partition 108, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 10.0 in stage 2.0 (TID 522) in 96 ms on ip-172-23-70-80.ec2.internal (executor 2) (13/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 109.0 in stage 2.0 (TID 621, ip-172-23-70-80.ec2.internal, executor 2, partition 109, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 74.0 in stage 2.0 (TID 586) in 90 ms on ip-172-23-70-80.ec2.internal (executor 2) (14/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 110.0 in stage 2.0 (TID 622, ip-172-23-70-80.ec2.internal, executor 2, partition 110, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 66.0 in stage 2.0 (TID 578) in 91 ms on ip-172-23-70-80.ec2.internal (executor 2) (15/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 111.0 in stage 2.0 (TID 623, ip-172-23-70-80.ec2.internal, executor 2, partition 111, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 30.0 in stage 2.0 (TID 542) in 97 ms on ip-172-23-70-80.ec2.internal (executor 2) (16/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 112.0 in stage 2.0 (TID 624, ip-172-23-70-80.ec2.internal, executor 2, partition 112, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 32.0 in stage 2.0 (TID 544) in 98 ms on ip-172-23-70-80.ec2.internal (executor 2) (17/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 113.0 in stage 2.0 (TID 625, ip-172-23-70-80.ec2.internal, executor 2, partition 113, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 72.0 in stage 2.0 (TID 584) in 94 ms on ip-172-23-70-80.ec2.internal (executor 2) (18/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 114.0 in stage 2.0 (TID 626, ip-172-23-70-80.ec2.internal, executor 2, partition 114, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 60.0 in stage 2.0 (TID 572) in 95 ms on ip-172-23-70-80.ec2.internal (executor 2) (19/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 115.0 in stage 2.0 (TID 627, ip-172-23-70-80.ec2.internal, executor 2, partition 115, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 6.0 in stage 2.0 (TID 518) in 102 ms on ip-172-23-70-80.ec2.internal (executor 2) (20/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 116.0 in stage 2.0 (TID 628, ip-172-23-70-80.ec2.internal, executor 2, partition 116, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 0.0 in stage 2.0 (TID 512) in 104 ms on ip-172-23-70-80.ec2.internal (executor 2) (21/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 117.0 in stage 2.0 (TID 629, ip-172-23-70-80.ec2.internal, executor 2, partition 117, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 4.0 in stage 2.0 (TID 516) in 104 ms on ip-172-23-70-80.ec2.internal (executor 2) (22/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 118.0 in stage 2.0 (TID 630, ip-172-23-70-80.ec2.internal, executor 2, partition 118, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 34.0 in stage 2.0 (TID 546) in 103 ms on ip-172-23-70-80.ec2.internal (executor 2) (23/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 119.0 in stage 2.0 (TID 631, ip-172-23-70-80.ec2.internal, executor 2, partition 119, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 22.0 in stage 2.0 (TID 534) in 105 ms on ip-172-23-70-80.ec2.internal (executor 2) (24/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 120.0 in stage 2.0 (TID 632, ip-172-23-70-80.ec2.internal, executor 2, partition 120, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 12.0 in stage 2.0 (TID 524) in 107 ms on ip-172-23-70-80.ec2.internal (executor 2) (25/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 121.0 in stage 2.0 (TID 633, ip-172-23-75-58.ec2.internal, executor 1, partition 121, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 53.0 in stage 2.0 (TID 565) in 102 ms on ip-172-23-75-58.ec2.internal (executor 1) (26/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 122.0 in stage 2.0 (TID 634, ip-172-23-75-58.ec2.internal, executor 1, partition 122, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 95.0 in stage 2.0 (TID 607) in 94 ms on ip-172-23-75-58.ec2.internal (executor 1) (27/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 123.0 in stage 2.0 (TID 635, ip-172-23-75-58.ec2.internal, executor 1, partition 123, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 124.0 in stage 2.0 (TID 636, ip-172-23-75-58.ec2.internal, executor 1, partition 124, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 125.0 in stage 2.0 (TID 637, ip-172-23-75-58.ec2.internal, executor 1, partition 125, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 67.0 in stage 2.0 (TID 579) in 106 ms on ip-172-23-75-58.ec2.internal (executor 1) (28/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 69.0 in stage 2.0 (TID 581) in 106 ms on ip-172-23-75-58.ec2.internal (executor 1) (29/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 126.0 in stage 2.0 (TID 638, ip-172-23-75-58.ec2.internal, executor 1, partition 126, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 127.0 in stage 2.0 (TID 639, ip-172-23-75-58.ec2.internal, executor 1, partition 127, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 128.0 in stage 2.0 (TID 640, ip-172-23-75-58.ec2.internal, executor 1, partition 128, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 129.0 in stage 2.0 (TID 641, ip-172-23-75-58.ec2.internal, executor 1, partition 129, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 130.0 in stage 2.0 (TID 642, ip-172-23-75-58.ec2.internal, executor 1, partition 130, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 131.0 in stage 2.0 (TID 643, ip-172-23-75-58.ec2.internal, executor 1, partition 131, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 132.0 in stage 2.0 (TID 644, ip-172-23-75-58.ec2.internal, executor 1, partition 132, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 133.0 in stage 2.0 (TID 645, ip-172-23-75-58.ec2.internal, executor 1, partition 133, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 134.0 in stage 2.0 (TID 646, ip-172-23-75-58.ec2.internal, executor 1, partition 134, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 135.0 in stage 2.0 (TID 647, ip-172-23-75-58.ec2.internal, executor 1, partition 135, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 136.0 in stage 2.0 (TID 648, ip-172-23-75-58.ec2.internal, executor 1, partition 136, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 137.0 in stage 2.0 (TID 649, ip-172-23-75-58.ec2.internal, executor 1, partition 137, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 83.0 in stage 2.0 (TID 595) in 108 ms on ip-172-23-75-58.ec2.internal (executor 1) (30/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 85.0 in stage 2.0 (TID 597) in 108 ms on ip-172-23-75-58.ec2.internal (executor 1) (31/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 73.0 in stage 2.0 (TID 585) in 113 ms on ip-172-23-75-58.ec2.internal (executor 1) (32/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 81.0 in stage 2.0 (TID 593) in 112 ms on ip-172-23-75-58.ec2.internal (executor 1) (33/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 29.0 in stage 2.0 (TID 541) in 119 ms on ip-172-23-75-58.ec2.internal (executor 1) (34/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 15.0 in stage 2.0 (TID 527) in 120 ms on ip-172-23-75-58.ec2.internal (executor 1) (35/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 13.0 in stage 2.0 (TID 525) in 120 ms on ip-172-23-75-58.ec2.internal (executor 1) (36/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 51.0 in stage 2.0 (TID 563) in 116 ms on ip-172-23-75-58.ec2.internal (executor 1) (37/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 11.0 in stage 2.0 (TID 523) in 121 ms on ip-172-23-75-58.ec2.internal (executor 1) (38/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 77.0 in stage 2.0 (TID 589) in 113 ms on ip-172-23-75-58.ec2.internal (executor 1) (39/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 1.0 in stage 2.0 (TID 513) in 122 ms on ip-172-23-75-58.ec2.internal (executor 1) (40/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 93.0 in stage 2.0 (TID 605) in 108 ms on ip-172-23-75-58.ec2.internal (executor 1) (41/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 89.0 in stage 2.0 (TID 601) in 109 ms on ip-172-23-75-58.ec2.internal (executor 1) (42/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 91.0 in stage 2.0 (TID 603) in 112 ms on ip-172-23-75-58.ec2.internal (executor 1) (43/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 138.0 in stage 2.0 (TID 650, ip-172-23-75-58.ec2.internal, executor 1, partition 138, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 7.0 in stage 2.0 (TID 519) in 126 ms on ip-172-23-75-58.ec2.internal (executor 1) (44/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 139.0 in stage 2.0 (TID 651, ip-172-23-75-58.ec2.internal, executor 1, partition 139, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 27.0 in stage 2.0 (TID 539) in 125 ms on ip-172-23-75-58.ec2.internal (executor 1) (45/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 140.0 in stage 2.0 (TID 652, ip-172-23-75-58.ec2.internal, executor 1, partition 140, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 23.0 in stage 2.0 (TID 535) in 127 ms on ip-172-23-75-58.ec2.internal (executor 1) (46/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 141.0 in stage 2.0 (TID 653, ip-172-23-75-58.ec2.internal, executor 1, partition 141, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 9.0 in stage 2.0 (TID 521) in 129 ms on ip-172-23-75-58.ec2.internal (executor 1) (47/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 142.0 in stage 2.0 (TID 654, ip-172-23-75-58.ec2.internal, executor 1, partition 142, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 87.0 in stage 2.0 (TID 599) in 118 ms on ip-172-23-75-58.ec2.internal (executor 1) (48/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 143.0 in stage 2.0 (TID 655, ip-172-23-75-58.ec2.internal, executor 1, partition 143, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 61.0 in stage 2.0 (TID 573) in 125 ms on ip-172-23-75-58.ec2.internal (executor 1) (49/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 144.0 in stage 2.0 (TID 656, ip-172-23-75-58.ec2.internal, executor 1, partition 144, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 5.0 in stage 2.0 (TID 517) in 132 ms on ip-172-23-75-58.ec2.internal (executor 1) (50/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 145.0 in stage 2.0 (TID 657, ip-172-23-75-58.ec2.internal, executor 1, partition 145, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 59.0 in stage 2.0 (TID 571) in 127 ms on ip-172-23-75-58.ec2.internal (executor 1) (51/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 146.0 in stage 2.0 (TID 658, ip-172-23-75-58.ec2.internal, executor 1, partition 146, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 17.0 in stage 2.0 (TID 529) in 133 ms on ip-172-23-75-58.ec2.internal (executor 1) (52/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 147.0 in stage 2.0 (TID 659, ip-172-23-75-58.ec2.internal, executor 1, partition 147, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 45.0 in stage 2.0 (TID 557) in 130 ms on ip-172-23-75-58.ec2.internal (executor 1) (53/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 148.0 in stage 2.0 (TID 660, ip-172-23-75-58.ec2.internal, executor 1, partition 148, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 71.0 in stage 2.0 (TID 583) in 130 ms on ip-172-23-75-58.ec2.internal (executor 1) (54/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 149.0 in stage 2.0 (TID 661, ip-172-23-75-58.ec2.internal, executor 1, partition 149, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 3.0 in stage 2.0 (TID 515) in 141 ms on ip-172-23-75-58.ec2.internal (executor 1) (55/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 150.0 in stage 2.0 (TID 662, ip-172-23-75-58.ec2.internal, executor 1, partition 150, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 39.0 in stage 2.0 (TID 551) in 139 ms on ip-172-23-75-58.ec2.internal (executor 1) (56/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 151.0 in stage 2.0 (TID 663, ip-172-23-75-58.ec2.internal, executor 1, partition 151, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 75.0 in stage 2.0 (TID 587) in 136 ms on ip-172-23-75-58.ec2.internal (executor 1) (57/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 152.0 in stage 2.0 (TID 664, ip-172-23-75-58.ec2.internal, executor 1, partition 152, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 64.0 in stage 2.0 (TID 576) in 138 ms on ip-172-23-70-80.ec2.internal (executor 2) (58/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 153.0 in stage 2.0 (TID 665, ip-172-23-70-80.ec2.internal, executor 2, partition 153, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 14.0 in stage 2.0 (TID 526) in 144 ms on ip-172-23-70-80.ec2.internal (executor 2) (59/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 154.0 in stage 2.0 (TID 666, ip-172-23-70-80.ec2.internal, executor 2, partition 154, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 47.0 in stage 2.0 (TID 559) in 141 ms on ip-172-23-75-58.ec2.internal (executor 1) (60/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 155.0 in stage 2.0 (TID 667, ip-172-23-75-58.ec2.internal, executor 1, partition 155, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 35.0 in stage 2.0 (TID 547) in 146 ms on ip-172-23-75-58.ec2.internal (executor 1) (61/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 156.0 in stage 2.0 (TID 668, ip-172-23-75-58.ec2.internal, executor 1, partition 156, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 63.0 in stage 2.0 (TID 575) in 144 ms on ip-172-23-75-58.ec2.internal (executor 1) (62/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 157.0 in stage 2.0 (TID 669, ip-172-23-75-58.ec2.internal, executor 1, partition 157, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 57.0 in stage 2.0 (TID 569) in 145 ms on ip-172-23-75-58.ec2.internal (executor 1) (63/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 158.0 in stage 2.0 (TID 670, ip-172-23-75-58.ec2.internal, executor 1, partition 158, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 43.0 in stage 2.0 (TID 555) in 147 ms on ip-172-23-75-58.ec2.internal (executor 1) (64/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 159.0 in stage 2.0 (TID 671, ip-172-23-75-58.ec2.internal, executor 1, partition 159, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 49.0 in stage 2.0 (TID 561) in 151 ms on ip-172-23-75-58.ec2.internal (executor 1) (65/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 160.0 in stage 2.0 (TID 672, ip-172-23-75-58.ec2.internal, executor 1, partition 160, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 41.0 in stage 2.0 (TID 553) in 154 ms on ip-172-23-75-58.ec2.internal (executor 1) (66/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 161.0 in stage 2.0 (TID 673, ip-172-23-75-58.ec2.internal, executor 1, partition 161, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 79.0 in stage 2.0 (TID 591) in 149 ms on ip-172-23-75-58.ec2.internal (executor 1) (67/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 162.0 in stage 2.0 (TID 674, ip-172-23-75-58.ec2.internal, executor 1, partition 162, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 31.0 in stage 2.0 (TID 543) in 156 ms on ip-172-23-75-58.ec2.internal (executor 1) (68/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 163.0 in stage 2.0 (TID 675, ip-172-23-75-58.ec2.internal, executor 1, partition 163, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 44.0 in stage 2.0 (TID 556) in 153 ms on ip-172-23-70-80.ec2.internal (executor 2) (69/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 164.0 in stage 2.0 (TID 676, ip-172-23-70-80.ec2.internal, executor 2, partition 164, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 70.0 in stage 2.0 (TID 582) in 152 ms on ip-172-23-70-80.ec2.internal (executor 2) (70/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 165.0 in stage 2.0 (TID 677, ip-172-23-70-80.ec2.internal, executor 2, partition 165, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 24.0 in stage 2.0 (TID 536) in 159 ms on ip-172-23-70-80.ec2.internal (executor 2) (71/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 166.0 in stage 2.0 (TID 678, ip-172-23-70-80.ec2.internal, executor 2, partition 166, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 90.0 in stage 2.0 (TID 602) in 149 ms on ip-172-23-70-80.ec2.internal (executor 2) (72/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 167.0 in stage 2.0 (TID 679, ip-172-23-70-80.ec2.internal, executor 2, partition 167, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 168.0 in stage 2.0 (TID 680, ip-172-23-70-80.ec2.internal, executor 2, partition 168, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 56.0 in stage 2.0 (TID 568) in 159 ms on ip-172-23-70-80.ec2.internal (executor 2) (73/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 169.0 in stage 2.0 (TID 681, ip-172-23-70-80.ec2.internal, executor 2, partition 169, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 42.0 in stage 2.0 (TID 554) in 161 ms on ip-172-23-70-80.ec2.internal (executor 2) (74/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 170.0 in stage 2.0 (TID 682, ip-172-23-70-80.ec2.internal, executor 2, partition 170, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 84.0 in stage 2.0 (TID 596) in 156 ms on ip-172-23-70-80.ec2.internal (executor 2) (75/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 171.0 in stage 2.0 (TID 683, ip-172-23-70-80.ec2.internal, executor 2, partition 171, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 36.0 in stage 2.0 (TID 548) in 167 ms on ip-172-23-70-80.ec2.internal (executor 2) (76/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 172.0 in stage 2.0 (TID 684, ip-172-23-70-80.ec2.internal, executor 2, partition 172, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 8.0 in stage 2.0 (TID 520) in 171 ms on ip-172-23-70-80.ec2.internal (executor 2) (77/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 173.0 in stage 2.0 (TID 685, ip-172-23-70-80.ec2.internal, executor 2, partition 173, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 174.0 in stage 2.0 (TID 686, ip-172-23-70-80.ec2.internal, executor 2, partition 174, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 2.0 in stage 2.0 (TID 514) in 174 ms on ip-172-23-70-80.ec2.internal (executor 2) (78/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 38.0 in stage 2.0 (TID 550) in 171 ms on ip-172-23-70-80.ec2.internal (executor 2) (79/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 175.0 in stage 2.0 (TID 687, ip-172-23-70-80.ec2.internal, executor 2, partition 175, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 40.0 in stage 2.0 (TID 552) in 173 ms on ip-172-23-70-80.ec2.internal (executor 2) (80/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 176.0 in stage 2.0 (TID 688, ip-172-23-70-80.ec2.internal, executor 2, partition 176, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 58.0 in stage 2.0 (TID 570) in 172 ms on ip-172-23-70-80.ec2.internal (executor 2) (81/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 177.0 in stage 2.0 (TID 689, ip-172-23-75-58.ec2.internal, executor 1, partition 177, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 25.0 in stage 2.0 (TID 537) in 177 ms on ip-172-23-75-58.ec2.internal (executor 1) (82/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 178.0 in stage 2.0 (TID 690, ip-172-23-70-80.ec2.internal, executor 2, partition 178, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 46.0 in stage 2.0 (TID 558) in 175 ms on ip-172-23-70-80.ec2.internal (executor 2) (83/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 179.0 in stage 2.0 (TID 691, ip-172-23-70-80.ec2.internal, executor 2, partition 179, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 20.0 in stage 2.0 (TID 532) in 180 ms on ip-172-23-70-80.ec2.internal (executor 2) (84/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 180.0 in stage 2.0 (TID 692, ip-172-23-70-80.ec2.internal, executor 2, partition 180, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 62.0 in stage 2.0 (TID 574) in 177 ms on ip-172-23-70-80.ec2.internal (executor 2) (85/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 181.0 in stage 2.0 (TID 693, ip-172-23-75-58.ec2.internal, executor 1, partition 181, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 19.0 in stage 2.0 (TID 531) in 183 ms on ip-172-23-75-58.ec2.internal (executor 1) (86/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 182.0 in stage 2.0 (TID 694, ip-172-23-75-58.ec2.internal, executor 1, partition 182, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 37.0 in stage 2.0 (TID 549) in 182 ms on ip-172-23-75-58.ec2.internal (executor 1) (87/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 183.0 in stage 2.0 (TID 695, ip-172-23-70-80.ec2.internal, executor 2, partition 183, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 18.0 in stage 2.0 (TID 530) in 186 ms on ip-172-23-70-80.ec2.internal (executor 2) (88/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 184.0 in stage 2.0 (TID 696, ip-172-23-70-80.ec2.internal, executor 2, partition 184, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 54.0 in stage 2.0 (TID 566) in 183 ms on ip-172-23-70-80.ec2.internal (executor 2) (89/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 185.0 in stage 2.0 (TID 697, ip-172-23-70-80.ec2.internal, executor 2, partition 185, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 186.0 in stage 2.0 (TID 698, ip-172-23-70-80.ec2.internal, executor 2, partition 186, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 92.0 in stage 2.0 (TID 604) in 178 ms on ip-172-23-70-80.ec2.internal (executor 2) (90/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 48.0 in stage 2.0 (TID 560) in 186 ms on ip-172-23-70-80.ec2.internal (executor 2) (91/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 187.0 in stage 2.0 (TID 699, ip-172-23-70-80.ec2.internal, executor 2, partition 187, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 16.0 in stage 2.0 (TID 528) in 192 ms on ip-172-23-70-80.ec2.internal (executor 2) (92/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 188.0 in stage 2.0 (TID 700, ip-172-23-70-80.ec2.internal, executor 2, partition 188, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 96.0 in stage 2.0 (TID 608) in 113 ms on ip-172-23-70-80.ec2.internal (executor 2) (93/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 189.0 in stage 2.0 (TID 701, ip-172-23-70-80.ec2.internal, executor 2, partition 189, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 97.0 in stage 2.0 (TID 609) in 110 ms on ip-172-23-70-80.ec2.internal (executor 2) (94/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 190.0 in stage 2.0 (TID 702, ip-172-23-75-58.ec2.internal, executor 1, partition 190, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 33.0 in stage 2.0 (TID 545) in 193 ms on ip-172-23-75-58.ec2.internal (executor 1) (95/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 191.0 in stage 2.0 (TID 703, ip-172-23-70-80.ec2.internal, executor 2, partition 191, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 98.0 in stage 2.0 (TID 610) in 111 ms on ip-172-23-70-80.ec2.internal (executor 2) (96/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 192.0 in stage 2.0 (TID 704, ip-172-23-70-80.ec2.internal, executor 2, partition 192, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 103.0 in stage 2.0 (TID 615) in 106 ms on ip-172-23-70-80.ec2.internal (executor 2) (97/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 193.0 in stage 2.0 (TID 705, ip-172-23-70-80.ec2.internal, executor 2, partition 193, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 104.0 in stage 2.0 (TID 616) in 106 ms on ip-172-23-70-80.ec2.internal (executor 2) (98/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 194.0 in stage 2.0 (TID 706, ip-172-23-70-80.ec2.internal, executor 2, partition 194, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 102.0 in stage 2.0 (TID 614) in 110 ms on ip-172-23-70-80.ec2.internal (executor 2) (99/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 100.0 in stage 2.0 (TID 612) in 113 ms on ip-172-23-70-80.ec2.internal (executor 2) (100/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 195.0 in stage 2.0 (TID 707, ip-172-23-70-80.ec2.internal, executor 2, partition 195, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 99.0 in stage 2.0 (TID 611) in 115 ms on ip-172-23-70-80.ec2.internal (executor 2) (101/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 196.0 in stage 2.0 (TID 708, ip-172-23-70-80.ec2.internal, executor 2, partition 196, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 105.0 in stage 2.0 (TID 617) in 109 ms on ip-172-23-70-80.ec2.internal (executor 2) (102/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 197.0 in stage 2.0 (TID 709, ip-172-23-70-80.ec2.internal, executor 2, partition 197, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 198.0 in stage 2.0 (TID 710, ip-172-23-70-80.ec2.internal, executor 2, partition 198, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 101.0 in stage 2.0 (TID 613) in 115 ms on ip-172-23-70-80.ec2.internal (executor 2) (103/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 199.0 in stage 2.0 (TID 711, ip-172-23-70-80.ec2.internal, executor 2, partition 199, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 113.0 in stage 2.0 (TID 625) in 105 ms on ip-172-23-70-80.ec2.internal (executor 2) (104/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 200.0 in stage 2.0 (TID 712, ip-172-23-70-80.ec2.internal, executor 2, partition 200, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 108.0 in stage 2.0 (TID 620) in 110 ms on ip-172-23-70-80.ec2.internal (executor 2) (105/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 201.0 in stage 2.0 (TID 713, ip-172-23-75-58.ec2.internal, executor 1, partition 201, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 122.0 in stage 2.0 (TID 634) in 98 ms on ip-172-23-75-58.ec2.internal (executor 1) (106/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 202.0 in stage 2.0 (TID 714, ip-172-23-70-80.ec2.internal, executor 2, partition 202, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 106.0 in stage 2.0 (TID 618) in 114 ms on ip-172-23-70-80.ec2.internal (executor 2) (107/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 203.0 in stage 2.0 (TID 715, ip-172-23-70-80.ec2.internal, executor 2, partition 203, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 117.0 in stage 2.0 (TID 629) in 106 ms on ip-172-23-70-80.ec2.internal (executor 2) (108/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 204.0 in stage 2.0 (TID 716, ip-172-23-70-80.ec2.internal, executor 2, partition 204, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 109.0 in stage 2.0 (TID 621) in 113 ms on ip-172-23-70-80.ec2.internal (executor 2) (109/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 205.0 in stage 2.0 (TID 717, ip-172-23-70-80.ec2.internal, executor 2, partition 205, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 111.0 in stage 2.0 (TID 623) in 112 ms on ip-172-23-70-80.ec2.internal (executor 2) (110/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 206.0 in stage 2.0 (TID 718, ip-172-23-70-80.ec2.internal, executor 2, partition 206, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 110.0 in stage 2.0 (TID 622) in 114 ms on ip-172-23-70-80.ec2.internal (executor 2) (111/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 207.0 in stage 2.0 (TID 719, ip-172-23-70-80.ec2.internal, executor 2, partition 207, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 112.0 in stage 2.0 (TID 624) in 114 ms on ip-172-23-70-80.ec2.internal (executor 2) (112/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 208.0 in stage 2.0 (TID 720, ip-172-23-70-80.ec2.internal, executor 2, partition 208, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 115.0 in stage 2.0 (TID 627) in 112 ms on ip-172-23-70-80.ec2.internal (executor 2) (113/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 209.0 in stage 2.0 (TID 721, ip-172-23-70-80.ec2.internal, executor 2, partition 209, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 116.0 in stage 2.0 (TID 628) in 113 ms on ip-172-23-70-80.ec2.internal (executor 2) (114/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 210.0 in stage 2.0 (TID 722, ip-172-23-75-58.ec2.internal, executor 1, partition 210, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 21.0 in stage 2.0 (TID 533) in 214 ms on ip-172-23-75-58.ec2.internal (executor 1) (115/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 211.0 in stage 2.0 (TID 723, ip-172-23-75-58.ec2.internal, executor 1, partition 211, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 125.0 in stage 2.0 (TID 637) in 103 ms on ip-172-23-75-58.ec2.internal (executor 1) (116/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 212.0 in stage 2.0 (TID 724, ip-172-23-75-58.ec2.internal, executor 1, partition 212, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 213.0 in stage 2.0 (TID 725, ip-172-23-75-58.ec2.internal, executor 1, partition 213, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 123.0 in stage 2.0 (TID 635) in 107 ms on ip-172-23-75-58.ec2.internal (executor 1) (117/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 121.0 in stage 2.0 (TID 633) in 111 ms on ip-172-23-75-58.ec2.internal (executor 1) (118/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 214.0 in stage 2.0 (TID 726, ip-172-23-75-58.ec2.internal, executor 1, partition 214, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 124.0 in stage 2.0 (TID 636) in 107 ms on ip-172-23-75-58.ec2.internal (executor 1) (119/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 215.0 in stage 2.0 (TID 727, ip-172-23-75-58.ec2.internal, executor 1, partition 215, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 130.0 in stage 2.0 (TID 642) in 106 ms on ip-172-23-75-58.ec2.internal (executor 1) (120/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 216.0 in stage 2.0 (TID 728, ip-172-23-75-58.ec2.internal, executor 1, partition 216, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 127.0 in stage 2.0 (TID 639) in 108 ms on ip-172-23-75-58.ec2.internal (executor 1) (121/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 217.0 in stage 2.0 (TID 729, ip-172-23-75-58.ec2.internal, executor 1, partition 217, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 126.0 in stage 2.0 (TID 638) in 110 ms on ip-172-23-75-58.ec2.internal (executor 1) (122/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 218.0 in stage 2.0 (TID 730, ip-172-23-75-58.ec2.internal, executor 1, partition 218, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 129.0 in stage 2.0 (TID 641) in 112 ms on ip-172-23-75-58.ec2.internal (executor 1) (123/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 219.0 in stage 2.0 (TID 731, ip-172-23-75-58.ec2.internal, executor 1, partition 219, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 131.0 in stage 2.0 (TID 643) in 112 ms on ip-172-23-75-58.ec2.internal (executor 1) (124/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 220.0 in stage 2.0 (TID 732, ip-172-23-75-58.ec2.internal, executor 1, partition 220, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 134.0 in stage 2.0 (TID 646) in 113 ms on ip-172-23-75-58.ec2.internal (executor 1) (125/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 221.0 in stage 2.0 (TID 733, ip-172-23-75-58.ec2.internal, executor 1, partition 221, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 128.0 in stage 2.0 (TID 640) in 116 ms on ip-172-23-75-58.ec2.internal (executor 1) (126/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 222.0 in stage 2.0 (TID 734, ip-172-23-75-58.ec2.internal, executor 1, partition 222, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 137.0 in stage 2.0 (TID 649) in 114 ms on ip-172-23-75-58.ec2.internal (executor 1) (127/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 223.0 in stage 2.0 (TID 735, ip-172-23-70-80.ec2.internal, executor 2, partition 223, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 107.0 in stage 2.0 (TID 619) in 139 ms on ip-172-23-70-80.ec2.internal (executor 2) (128/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 224.0 in stage 2.0 (TID 736, ip-172-23-75-58.ec2.internal, executor 1, partition 224, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 133.0 in stage 2.0 (TID 645) in 118 ms on ip-172-23-75-58.ec2.internal (executor 1) (129/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 225.0 in stage 2.0 (TID 737, ip-172-23-75-58.ec2.internal, executor 1, partition 225, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 132.0 in stage 2.0 (TID 644) in 120 ms on ip-172-23-75-58.ec2.internal (executor 1) (130/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 226.0 in stage 2.0 (TID 738, ip-172-23-75-58.ec2.internal, executor 1, partition 226, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 136.0 in stage 2.0 (TID 648) in 120 ms on ip-172-23-75-58.ec2.internal (executor 1) (131/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 227.0 in stage 2.0 (TID 739, ip-172-23-75-58.ec2.internal, executor 1, partition 227, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 135.0 in stage 2.0 (TID 647) in 121 ms on ip-172-23-75-58.ec2.internal (executor 1) (132/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 228.0 in stage 2.0 (TID 740, ip-172-23-75-58.ec2.internal, executor 1, partition 228, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 65.0 in stage 2.0 (TID 577) in 233 ms on ip-172-23-75-58.ec2.internal (executor 1) (133/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 229.0 in stage 2.0 (TID 741, ip-172-23-75-58.ec2.internal, executor 1, partition 229, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 55.0 in stage 2.0 (TID 567) in 235 ms on ip-172-23-75-58.ec2.internal (executor 1) (134/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 230.0 in stage 2.0 (TID 742, ip-172-23-75-58.ec2.internal, executor 1, partition 230, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 143.0 in stage 2.0 (TID 655) in 111 ms on ip-172-23-75-58.ec2.internal (executor 1) (135/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 231.0 in stage 2.0 (TID 743, ip-172-23-75-58.ec2.internal, executor 1, partition 231, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 140.0 in stage 2.0 (TID 652) in 115 ms on ip-172-23-75-58.ec2.internal (executor 1) (136/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 232.0 in stage 2.0 (TID 744, ip-172-23-75-58.ec2.internal, executor 1, partition 232, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 139.0 in stage 2.0 (TID 651) in 116 ms on ip-172-23-75-58.ec2.internal (executor 1) (137/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 233.0 in stage 2.0 (TID 745, ip-172-23-75-58.ec2.internal, executor 1, partition 233, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 138.0 in stage 2.0 (TID 650) in 118 ms on ip-172-23-75-58.ec2.internal (executor 1) (138/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 234.0 in stage 2.0 (TID 746, ip-172-23-75-58.ec2.internal, executor 1, partition 234, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 145.0 in stage 2.0 (TID 657) in 112 ms on ip-172-23-75-58.ec2.internal (executor 1) (139/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 235.0 in stage 2.0 (TID 747, ip-172-23-75-58.ec2.internal, executor 1, partition 235, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 142.0 in stage 2.0 (TID 654) in 116 ms on ip-172-23-75-58.ec2.internal (executor 1) (140/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 236.0 in stage 2.0 (TID 748, ip-172-23-70-80.ec2.internal, executor 2, partition 236, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 120.0 in stage 2.0 (TID 632) in 140 ms on ip-172-23-70-80.ec2.internal (executor 2) (141/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 237.0 in stage 2.0 (TID 749, ip-172-23-70-80.ec2.internal, executor 2, partition 237, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 119.0 in stage 2.0 (TID 631) in 142 ms on ip-172-23-70-80.ec2.internal (executor 2) (142/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 238.0 in stage 2.0 (TID 750, ip-172-23-75-58.ec2.internal, executor 1, partition 238, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 141.0 in stage 2.0 (TID 653) in 119 ms on ip-172-23-75-58.ec2.internal (executor 1) (143/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 239.0 in stage 2.0 (TID 751, ip-172-23-75-58.ec2.internal, executor 1, partition 239, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 144.0 in stage 2.0 (TID 656) in 117 ms on ip-172-23-75-58.ec2.internal (executor 1) (144/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 240.0 in stage 2.0 (TID 752, ip-172-23-75-58.ec2.internal, executor 1, partition 240, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 146.0 in stage 2.0 (TID 658) in 117 ms on ip-172-23-75-58.ec2.internal (executor 1) (145/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 241.0 in stage 2.0 (TID 753, ip-172-23-75-58.ec2.internal, executor 1, partition 241, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 150.0 in stage 2.0 (TID 662) in 111 ms on ip-172-23-75-58.ec2.internal (executor 1) (146/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 151.0 in stage 2.0 (TID 663) in 111 ms on ip-172-23-75-58.ec2.internal (executor 1) (147/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 242.0 in stage 2.0 (TID 754, ip-172-23-75-58.ec2.internal, executor 1, partition 242, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 149.0 in stage 2.0 (TID 661) in 116 ms on ip-172-23-75-58.ec2.internal (executor 1) (148/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 243.0 in stage 2.0 (TID 755, ip-172-23-75-58.ec2.internal, executor 1, partition 243, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 244.0 in stage 2.0 (TID 756, ip-172-23-70-80.ec2.internal, executor 2, partition 244, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 153.0 in stage 2.0 (TID 665) in 110 ms on ip-172-23-70-80.ec2.internal (executor 2) (149/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 245.0 in stage 2.0 (TID 757, ip-172-23-75-58.ec2.internal, executor 1, partition 245, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 155.0 in stage 2.0 (TID 667) in 109 ms on ip-172-23-75-58.ec2.internal (executor 1) (150/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 152.0 in stage 2.0 (TID 664) in 112 ms on ip-172-23-75-58.ec2.internal (executor 1) (151/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 246.0 in stage 2.0 (TID 758, ip-172-23-75-58.ec2.internal, executor 1, partition 246, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 147.0 in stage 2.0 (TID 659) in 122 ms on ip-172-23-75-58.ec2.internal (executor 1) (152/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 247.0 in stage 2.0 (TID 759, ip-172-23-75-58.ec2.internal, executor 1, partition 247, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 248.0 in stage 2.0 (TID 760, ip-172-23-75-58.ec2.internal, executor 1, partition 248, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 148.0 in stage 2.0 (TID 660) in 122 ms on ip-172-23-75-58.ec2.internal (executor 1) (153/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 159.0 in stage 2.0 (TID 671) in 106 ms on ip-172-23-75-58.ec2.internal (executor 1) (154/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 249.0 in stage 2.0 (TID 761, ip-172-23-75-58.ec2.internal, executor 1, partition 249, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 157.0 in stage 2.0 (TID 669) in 109 ms on ip-172-23-75-58.ec2.internal (executor 1) (155/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 250.0 in stage 2.0 (TID 762, ip-172-23-75-58.ec2.internal, executor 1, partition 250, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 118.0 in stage 2.0 (TID 630) in 155 ms on ip-172-23-70-80.ec2.internal (executor 2) (156/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 251.0 in stage 2.0 (TID 763, ip-172-23-70-80.ec2.internal, executor 2, partition 251, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 252.0 in stage 2.0 (TID 764, ip-172-23-75-58.ec2.internal, executor 1, partition 252, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 156.0 in stage 2.0 (TID 668) in 113 ms on ip-172-23-75-58.ec2.internal (executor 1) (157/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 158.0 in stage 2.0 (TID 670) in 111 ms on ip-172-23-75-58.ec2.internal (executor 1) (158/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 253.0 in stage 2.0 (TID 765, ip-172-23-75-58.ec2.internal, executor 1, partition 253, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 161.0 in stage 2.0 (TID 673) in 106 ms on ip-172-23-75-58.ec2.internal (executor 1) (159/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 254.0 in stage 2.0 (TID 766, ip-172-23-75-58.ec2.internal, executor 1, partition 254, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 162.0 in stage 2.0 (TID 674) in 105 ms on ip-172-23-75-58.ec2.internal (executor 1) (160/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 255.0 in stage 2.0 (TID 767, ip-172-23-75-58.ec2.internal, executor 1, partition 255, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 256.0 in stage 2.0 (TID 768, ip-172-23-70-80.ec2.internal, executor 2, partition 256, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 257.0 in stage 2.0 (TID 769, ip-172-23-75-58.ec2.internal, executor 1, partition 257, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 154.0 in stage 2.0 (TID 666) in 119 ms on ip-172-23-70-80.ec2.internal (executor 2) (161/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 160.0 in stage 2.0 (TID 672) in 109 ms on ip-172-23-75-58.ec2.internal (executor 1) (162/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 164.0 in stage 2.0 (TID 676) in 107 ms on ip-172-23-70-80.ec2.internal (executor 2) (163/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 258.0 in stage 2.0 (TID 770, ip-172-23-70-80.ec2.internal, executor 2, partition 258, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 166.0 in stage 2.0 (TID 678) in 106 ms on ip-172-23-70-80.ec2.internal (executor 2) (164/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 259.0 in stage 2.0 (TID 771, ip-172-23-70-80.ec2.internal, executor 2, partition 259, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 260.0 in stage 2.0 (TID 772, ip-172-23-70-80.ec2.internal, executor 2, partition 260, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 168.0 in stage 2.0 (TID 680) in 107 ms on ip-172-23-70-80.ec2.internal (executor 2) (165/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 261.0 in stage 2.0 (TID 773, ip-172-23-70-80.ec2.internal, executor 2, partition 261, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 173.0 in stage 2.0 (TID 685) in 99 ms on ip-172-23-70-80.ec2.internal (executor 2) (166/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 170.0 in stage 2.0 (TID 682) in 104 ms on ip-172-23-70-80.ec2.internal (executor 2) (167/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 262.0 in stage 2.0 (TID 774, ip-172-23-70-80.ec2.internal, executor 2, partition 262, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 177.0 in stage 2.0 (TID 689) in 94 ms on ip-172-23-75-58.ec2.internal (executor 1) (168/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 263.0 in stage 2.0 (TID 775, ip-172-23-75-58.ec2.internal, executor 1, partition 263, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 264.0 in stage 2.0 (TID 776, ip-172-23-70-80.ec2.internal, executor 2, partition 264, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 175.0 in stage 2.0 (TID 687) in 97 ms on ip-172-23-70-80.ec2.internal (executor 2) (169/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 265.0 in stage 2.0 (TID 777, ip-172-23-70-80.ec2.internal, executor 2, partition 265, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 171.0 in stage 2.0 (TID 683) in 105 ms on ip-172-23-70-80.ec2.internal (executor 2) (170/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 172.0 in stage 2.0 (TID 684) in 104 ms on ip-172-23-70-80.ec2.internal (executor 2) (171/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 266.0 in stage 2.0 (TID 778, ip-172-23-70-80.ec2.internal, executor 2, partition 266, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 181.0 in stage 2.0 (TID 693) in 91 ms on ip-172-23-75-58.ec2.internal (executor 1) (172/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 267.0 in stage 2.0 (TID 779, ip-172-23-75-58.ec2.internal, executor 1, partition 267, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 268.0 in stage 2.0 (TID 780, ip-172-23-75-58.ec2.internal, executor 1, partition 268, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 182.0 in stage 2.0 (TID 694) in 91 ms on ip-172-23-75-58.ec2.internal (executor 1) (173/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 269.0 in stage 2.0 (TID 781, ip-172-23-70-80.ec2.internal, executor 2, partition 269, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 167.0 in stage 2.0 (TID 679) in 115 ms on ip-172-23-70-80.ec2.internal (executor 2) (174/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 169.0 in stage 2.0 (TID 681) in 111 ms on ip-172-23-70-80.ec2.internal (executor 2) (175/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 270.0 in stage 2.0 (TID 782, ip-172-23-70-80.ec2.internal, executor 2, partition 270, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 174.0 in stage 2.0 (TID 686) in 105 ms on ip-172-23-70-80.ec2.internal (executor 2) (176/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 271.0 in stage 2.0 (TID 783, ip-172-23-70-80.ec2.internal, executor 2, partition 271, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 272.0 in stage 2.0 (TID 784, ip-172-23-70-80.ec2.internal, executor 2, partition 272, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 165.0 in stage 2.0 (TID 677) in 119 ms on ip-172-23-70-80.ec2.internal (executor 2) (177/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 273.0 in stage 2.0 (TID 785, ip-172-23-75-58.ec2.internal, executor 1, partition 273, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 190.0 in stage 2.0 (TID 702) in 84 ms on ip-172-23-75-58.ec2.internal (executor 1) (178/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 180.0 in stage 2.0 (TID 692) in 97 ms on ip-172-23-70-80.ec2.internal (executor 2) (179/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 274.0 in stage 2.0 (TID 786, ip-172-23-70-80.ec2.internal, executor 2, partition 274, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 178.0 in stage 2.0 (TID 690) in 100 ms on ip-172-23-70-80.ec2.internal (executor 2) (180/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 275.0 in stage 2.0 (TID 787, ip-172-23-70-80.ec2.internal, executor 2, partition 275, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 276.0 in stage 2.0 (TID 788, ip-172-23-75-58.ec2.internal, executor 1, partition 276, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 163.0 in stage 2.0 (TID 675) in 122 ms on ip-172-23-75-58.ec2.internal (executor 1) (181/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 277.0 in stage 2.0 (TID 789, ip-172-23-70-80.ec2.internal, executor 2, partition 277, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 184.0 in stage 2.0 (TID 696) in 92 ms on ip-172-23-70-80.ec2.internal (executor 2) (182/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 183.0 in stage 2.0 (TID 695) in 96 ms on ip-172-23-70-80.ec2.internal (executor 2) (183/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 278.0 in stage 2.0 (TID 790, ip-172-23-70-80.ec2.internal, executor 2, partition 278, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 179.0 in stage 2.0 (TID 691) in 101 ms on ip-172-23-70-80.ec2.internal (executor 2) (184/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 279.0 in stage 2.0 (TID 791, ip-172-23-70-80.ec2.internal, executor 2, partition 279, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 280.0 in stage 2.0 (TID 792, ip-172-23-70-80.ec2.internal, executor 2, partition 280, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 185.0 in stage 2.0 (TID 697) in 98 ms on ip-172-23-70-80.ec2.internal (executor 2) (185/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 281.0 in stage 2.0 (TID 793, ip-172-23-75-58.ec2.internal, executor 1, partition 281, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 201.0 in stage 2.0 (TID 713) in 80 ms on ip-172-23-75-58.ec2.internal (executor 1) (186/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 199.0 in stage 2.0 (TID 711) in 83 ms on ip-172-23-70-80.ec2.internal (executor 2) (187/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 282.0 in stage 2.0 (TID 794, ip-172-23-70-80.ec2.internal, executor 2, partition 282, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 191.0 in stage 2.0 (TID 703) in 92 ms on ip-172-23-70-80.ec2.internal (executor 2) (188/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 283.0 in stage 2.0 (TID 795, ip-172-23-70-80.ec2.internal, executor 2, partition 283, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 284.0 in stage 2.0 (TID 796, ip-172-23-75-58.ec2.internal, executor 1, partition 284, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 212.0 in stage 2.0 (TID 724) in 71 ms on ip-172-23-75-58.ec2.internal (executor 1) (189/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 285.0 in stage 2.0 (TID 797, ip-172-23-75-58.ec2.internal, executor 1, partition 285, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 210.0 in stage 2.0 (TID 722) in 78 ms on ip-172-23-75-58.ec2.internal (executor 1) (190/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 189.0 in stage 2.0 (TID 701) in 98 ms on ip-172-23-70-80.ec2.internal (executor 2) (191/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 286.0 in stage 2.0 (TID 798, ip-172-23-70-80.ec2.internal, executor 2, partition 286, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 200.0 in stage 2.0 (TID 712) in 87 ms on ip-172-23-70-80.ec2.internal (executor 2) (192/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 287.0 in stage 2.0 (TID 799, ip-172-23-70-80.ec2.internal, executor 2, partition 287, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 288.0 in stage 2.0 (TID 800, ip-172-23-70-80.ec2.internal, executor 2, partition 288, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 202.0 in stage 2.0 (TID 714) in 86 ms on ip-172-23-70-80.ec2.internal (executor 2) (193/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 289.0 in stage 2.0 (TID 801, ip-172-23-70-80.ec2.internal, executor 2, partition 289, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 196.0 in stage 2.0 (TID 708) in 92 ms on ip-172-23-70-80.ec2.internal (executor 2) (194/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 188.0 in stage 2.0 (TID 700) in 102 ms on ip-172-23-70-80.ec2.internal (executor 2) (195/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 290.0 in stage 2.0 (TID 802, ip-172-23-70-80.ec2.internal, executor 2, partition 290, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 214.0 in stage 2.0 (TID 726) in 75 ms on ip-172-23-75-58.ec2.internal (executor 1) (196/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 291.0 in stage 2.0 (TID 803, ip-172-23-75-58.ec2.internal, executor 1, partition 291, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 292.0 in stage 2.0 (TID 804, ip-172-23-70-80.ec2.internal, executor 2, partition 292, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 203.0 in stage 2.0 (TID 715) in 87 ms on ip-172-23-70-80.ec2.internal (executor 2) (197/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 293.0 in stage 2.0 (TID 805, ip-172-23-75-58.ec2.internal, executor 1, partition 293, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 213.0 in stage 2.0 (TID 725) in 79 ms on ip-172-23-75-58.ec2.internal (executor 1) (198/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 193.0 in stage 2.0 (TID 705) in 101 ms on ip-172-23-70-80.ec2.internal (executor 2) (199/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 294.0 in stage 2.0 (TID 806, ip-172-23-70-80.ec2.internal, executor 2, partition 294, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 216.0 in stage 2.0 (TID 728) in 75 ms on ip-172-23-75-58.ec2.internal (executor 1) (200/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 295.0 in stage 2.0 (TID 807, ip-172-23-75-58.ec2.internal, executor 1, partition 295, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 296.0 in stage 2.0 (TID 808, ip-172-23-70-80.ec2.internal, executor 2, partition 296, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 198.0 in stage 2.0 (TID 710) in 95 ms on ip-172-23-70-80.ec2.internal (executor 2) (201/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 297.0 in stage 2.0 (TID 809, ip-172-23-70-80.ec2.internal, executor 2, partition 297, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 204.0 in stage 2.0 (TID 716) in 89 ms on ip-172-23-70-80.ec2.internal (executor 2) (202/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 209.0 in stage 2.0 (TID 721) in 86 ms on ip-172-23-70-80.ec2.internal (executor 2) (203/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 298.0 in stage 2.0 (TID 810, ip-172-23-70-80.ec2.internal, executor 2, partition 298, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 205.0 in stage 2.0 (TID 717) in 89 ms on ip-172-23-70-80.ec2.internal (executor 2) (204/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 299.0 in stage 2.0 (TID 811, ip-172-23-70-80.ec2.internal, executor 2, partition 299, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 300.0 in stage 2.0 (TID 812, ip-172-23-75-58.ec2.internal, executor 1, partition 300, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 211.0 in stage 2.0 (TID 723) in 85 ms on ip-172-23-75-58.ec2.internal (executor 1) (205/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 301.0 in stage 2.0 (TID 813, ip-172-23-75-58.ec2.internal, executor 1, partition 301, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 215.0 in stage 2.0 (TID 727) in 82 ms on ip-172-23-75-58.ec2.internal (executor 1) (206/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 219.0 in stage 2.0 (TID 731) in 74 ms on ip-172-23-75-58.ec2.internal (executor 1) (207/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 302.0 in stage 2.0 (TID 814, ip-172-23-75-58.ec2.internal, executor 1, partition 302, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 217.0 in stage 2.0 (TID 729) in 79 ms on ip-172-23-75-58.ec2.internal (executor 1) (208/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 303.0 in stage 2.0 (TID 815, ip-172-23-75-58.ec2.internal, executor 1, partition 303, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 304.0 in stage 2.0 (TID 816, ip-172-23-75-58.ec2.internal, executor 1, partition 304, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 218.0 in stage 2.0 (TID 730) in 76 ms on ip-172-23-75-58.ec2.internal (executor 1) (209/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 305.0 in stage 2.0 (TID 817, ip-172-23-70-80.ec2.internal, executor 2, partition 305, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 208.0 in stage 2.0 (TID 720) in 91 ms on ip-172-23-70-80.ec2.internal (executor 2) (210/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 224.0 in stage 2.0 (TID 736) in 70 ms on ip-172-23-75-58.ec2.internal (executor 1) (211/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 306.0 in stage 2.0 (TID 818, ip-172-23-75-58.ec2.internal, executor 1, partition 306, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 207.0 in stage 2.0 (TID 719) in 92 ms on ip-172-23-70-80.ec2.internal (executor 2) (212/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 307.0 in stage 2.0 (TID 819, ip-172-23-70-80.ec2.internal, executor 2, partition 307, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 308.0 in stage 2.0 (TID 820, ip-172-23-70-80.ec2.internal, executor 2, partition 308, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 186.0 in stage 2.0 (TID 698) in 116 ms on ip-172-23-70-80.ec2.internal (executor 2) (213/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 309.0 in stage 2.0 (TID 821, ip-172-23-70-80.ec2.internal, executor 2, partition 309, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 176.0 in stage 2.0 (TID 688) in 132 ms on ip-172-23-70-80.ec2.internal (executor 2) (214/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 310.0 in stage 2.0 (TID 822, ip-172-23-70-80.ec2.internal, executor 2, partition 310, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 311.0 in stage 2.0 (TID 823, ip-172-23-70-80.ec2.internal, executor 2, partition 311, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 206.0 in stage 2.0 (TID 718) in 97 ms on ip-172-23-70-80.ec2.internal (executor 2) (215/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 312.0 in stage 2.0 (TID 824, ip-172-23-75-58.ec2.internal, executor 1, partition 312, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 194.0 in stage 2.0 (TID 706) in 110 ms on ip-172-23-70-80.ec2.internal (executor 2) (216/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 228.0 in stage 2.0 (TID 740) in 69 ms on ip-172-23-75-58.ec2.internal (executor 1) (217/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 222.0 in stage 2.0 (TID 734) in 76 ms on ip-172-23-75-58.ec2.internal (executor 1) (218/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 313.0 in stage 2.0 (TID 825, ip-172-23-75-58.ec2.internal, executor 1, partition 313, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 314.0 in stage 2.0 (TID 826, ip-172-23-75-58.ec2.internal, executor 1, partition 314, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 230.0 in stage 2.0 (TID 742) in 69 ms on ip-172-23-75-58.ec2.internal (executor 1) (219/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 315.0 in stage 2.0 (TID 827, ip-172-23-70-80.ec2.internal, executor 2, partition 315, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 187.0 in stage 2.0 (TID 699) in 118 ms on ip-172-23-70-80.ec2.internal (executor 2) (220/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 220.0 in stage 2.0 (TID 732) in 80 ms on ip-172-23-75-58.ec2.internal (executor 1) (221/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 316.0 in stage 2.0 (TID 828, ip-172-23-75-58.ec2.internal, executor 1, partition 316, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 227.0 in stage 2.0 (TID 739) in 73 ms on ip-172-23-75-58.ec2.internal (executor 1) (222/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 317.0 in stage 2.0 (TID 829, ip-172-23-75-58.ec2.internal, executor 1, partition 317, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 318.0 in stage 2.0 (TID 830, ip-172-23-75-58.ec2.internal, executor 1, partition 318, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 225.0 in stage 2.0 (TID 737) in 77 ms on ip-172-23-75-58.ec2.internal (executor 1) (223/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 319.0 in stage 2.0 (TID 831, ip-172-23-75-58.ec2.internal, executor 1, partition 319, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 229.0 in stage 2.0 (TID 741) in 74 ms on ip-172-23-75-58.ec2.internal (executor 1) (224/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 233.0 in stage 2.0 (TID 745) in 74 ms on ip-172-23-75-58.ec2.internal (executor 1) (225/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 320.0 in stage 2.0 (TID 832, ip-172-23-75-58.ec2.internal, executor 1, partition 320, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 232.0 in stage 2.0 (TID 744) in 75 ms on ip-172-23-75-58.ec2.internal (executor 1) (226/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 321.0 in stage 2.0 (TID 833, ip-172-23-75-58.ec2.internal, executor 1, partition 321, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 322.0 in stage 2.0 (TID 834, ip-172-23-75-58.ec2.internal, executor 1, partition 322, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 226.0 in stage 2.0 (TID 738) in 81 ms on ip-172-23-75-58.ec2.internal (executor 1) (227/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 323.0 in stage 2.0 (TID 835, ip-172-23-75-58.ec2.internal, executor 1, partition 323, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 235.0 in stage 2.0 (TID 747) in 73 ms on ip-172-23-75-58.ec2.internal (executor 1) (228/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 234.0 in stage 2.0 (TID 746) in 76 ms on ip-172-23-75-58.ec2.internal (executor 1) (229/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 324.0 in stage 2.0 (TID 836, ip-172-23-75-58.ec2.internal, executor 1, partition 324, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 231.0 in stage 2.0 (TID 743) in 79 ms on ip-172-23-75-58.ec2.internal (executor 1) (230/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 325.0 in stage 2.0 (TID 837, ip-172-23-75-58.ec2.internal, executor 1, partition 325, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 326.0 in stage 2.0 (TID 838, ip-172-23-75-58.ec2.internal, executor 1, partition 326, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 242.0 in stage 2.0 (TID 754) in 69 ms on ip-172-23-75-58.ec2.internal (executor 1) (231/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 327.0 in stage 2.0 (TID 839, ip-172-23-75-58.ec2.internal, executor 1, partition 327, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 239.0 in stage 2.0 (TID 751) in 73 ms on ip-172-23-75-58.ec2.internal (executor 1) (232/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 237.0 in stage 2.0 (TID 749) in 76 ms on ip-172-23-70-80.ec2.internal (executor 2) (233/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 328.0 in stage 2.0 (TID 840, ip-172-23-70-80.ec2.internal, executor 2, partition 328, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 238.0 in stage 2.0 (TID 750) in 75 ms on ip-172-23-75-58.ec2.internal (executor 1) (234/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 329.0 in stage 2.0 (TID 841, ip-172-23-75-58.ec2.internal, executor 1, partition 329, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 330.0 in stage 2.0 (TID 842, ip-172-23-75-58.ec2.internal, executor 1, partition 330, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 243.0 in stage 2.0 (TID 755) in 70 ms on ip-172-23-75-58.ec2.internal (executor 1) (235/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 331.0 in stage 2.0 (TID 843, ip-172-23-75-58.ec2.internal, executor 1, partition 331, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 248.0 in stage 2.0 (TID 760) in 70 ms on ip-172-23-75-58.ec2.internal (executor 1) (236/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 197.0 in stage 2.0 (TID 709) in 126 ms on ip-172-23-70-80.ec2.internal (executor 2) (237/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 332.0 in stage 2.0 (TID 844, ip-172-23-70-80.ec2.internal, executor 2, partition 332, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 244.0 in stage 2.0 (TID 756) in 74 ms on ip-172-23-70-80.ec2.internal (executor 2) (238/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 333.0 in stage 2.0 (TID 845, ip-172-23-70-80.ec2.internal, executor 2, partition 333, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 334.0 in stage 2.0 (TID 846, ip-172-23-70-80.ec2.internal, executor 2, partition 334, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 236.0 in stage 2.0 (TID 748) in 82 ms on ip-172-23-70-80.ec2.internal (executor 2) (239/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 335.0 in stage 2.0 (TID 847, ip-172-23-70-80.ec2.internal, executor 2, partition 335, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 195.0 in stage 2.0 (TID 707) in 128 ms on ip-172-23-70-80.ec2.internal (executor 2) (240/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 245.0 in stage 2.0 (TID 757) in 73 ms on ip-172-23-75-58.ec2.internal (executor 1) (241/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 336.0 in stage 2.0 (TID 848, ip-172-23-75-58.ec2.internal, executor 1, partition 336, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 241.0 in stage 2.0 (TID 753) in 78 ms on ip-172-23-75-58.ec2.internal (executor 1) (242/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 337.0 in stage 2.0 (TID 849, ip-172-23-75-58.ec2.internal, executor 1, partition 337, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 338.0 in stage 2.0 (TID 850, ip-172-23-75-58.ec2.internal, executor 1, partition 338, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 246.0 in stage 2.0 (TID 758) in 75 ms on ip-172-23-75-58.ec2.internal (executor 1) (243/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 339.0 in stage 2.0 (TID 851, ip-172-23-75-58.ec2.internal, executor 1, partition 339, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 254.0 in stage 2.0 (TID 766) in 69 ms on ip-172-23-75-58.ec2.internal (executor 1) (244/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 240.0 in stage 2.0 (TID 752) in 82 ms on ip-172-23-75-58.ec2.internal (executor 1) (245/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 340.0 in stage 2.0 (TID 852, ip-172-23-75-58.ec2.internal, executor 1, partition 340, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 252.0 in stage 2.0 (TID 764) in 73 ms on ip-172-23-75-58.ec2.internal (executor 1) (246/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 341.0 in stage 2.0 (TID 853, ip-172-23-75-58.ec2.internal, executor 1, partition 341, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 342.0 in stage 2.0 (TID 854, ip-172-23-75-58.ec2.internal, executor 1, partition 342, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 247.0 in stage 2.0 (TID 759) in 76 ms on ip-172-23-75-58.ec2.internal (executor 1) (247/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 343.0 in stage 2.0 (TID 855, ip-172-23-70-80.ec2.internal, executor 2, partition 343, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 256.0 in stage 2.0 (TID 768) in 70 ms on ip-172-23-70-80.ec2.internal (executor 2) (248/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 223.0 in stage 2.0 (TID 735) in 100 ms on ip-172-23-70-80.ec2.internal (executor 2) (249/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 344.0 in stage 2.0 (TID 856, ip-172-23-70-80.ec2.internal, executor 2, partition 344, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 260.0 in stage 2.0 (TID 772) in 67 ms on ip-172-23-70-80.ec2.internal (executor 2) (250/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 345.0 in stage 2.0 (TID 857, ip-172-23-70-80.ec2.internal, executor 2, partition 345, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 346.0 in stage 2.0 (TID 858, ip-172-23-75-58.ec2.internal, executor 1, partition 346, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 253.0 in stage 2.0 (TID 765) in 73 ms on ip-172-23-75-58.ec2.internal (executor 1) (251/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 347.0 in stage 2.0 (TID 859, ip-172-23-75-58.ec2.internal, executor 1, partition 347, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 250.0 in stage 2.0 (TID 762) in 78 ms on ip-172-23-75-58.ec2.internal (executor 1) (252/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 348.0 in stage 2.0 (TID 860, ip-172-23-75-58.ec2.internal, executor 1, partition 348, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 249.0 in stage 2.0 (TID 761) in 79 ms on ip-172-23-75-58.ec2.internal (executor 1) (253/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 257.0 in stage 2.0 (TID 769) in 73 ms on ip-172-23-75-58.ec2.internal (executor 1) (254/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 349.0 in stage 2.0 (TID 861, ip-172-23-75-58.ec2.internal, executor 1, partition 349, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 350.0 in stage 2.0 (TID 862, ip-172-23-75-58.ec2.internal, executor 1, partition 350, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 263.0 in stage 2.0 (TID 775) in 66 ms on ip-172-23-75-58.ec2.internal (executor 1) (255/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 255.0 in stage 2.0 (TID 767) in 75 ms on ip-172-23-75-58.ec2.internal (executor 1) (256/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 351.0 in stage 2.0 (TID 863, ip-172-23-75-58.ec2.internal, executor 1, partition 351, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 352.0 in stage 2.0 (TID 864, ip-172-23-70-80.ec2.internal, executor 2, partition 352, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 251.0 in stage 2.0 (TID 763) in 79 ms on ip-172-23-70-80.ec2.internal (executor 2) (257/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 262.0 in stage 2.0 (TID 774) in 69 ms on ip-172-23-70-80.ec2.internal (executor 2) (258/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 353.0 in stage 2.0 (TID 865, ip-172-23-70-80.ec2.internal, executor 2, partition 353, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 354.0 in stage 2.0 (TID 866, ip-172-23-75-58.ec2.internal, executor 1, partition 354, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 268.0 in stage 2.0 (TID 780) in 66 ms on ip-172-23-75-58.ec2.internal (executor 1) (259/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 276.0 in stage 2.0 (TID 788) in 63 ms on ip-172-23-75-58.ec2.internal (executor 1) (260/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 355.0 in stage 2.0 (TID 867, ip-172-23-75-58.ec2.internal, executor 1, partition 355, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 356.0 in stage 2.0 (TID 868, ip-172-23-75-58.ec2.internal, executor 1, partition 356, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 273.0 in stage 2.0 (TID 785) in 66 ms on ip-172-23-75-58.ec2.internal (executor 1) (261/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 267.0 in stage 2.0 (TID 779) in 73 ms on ip-172-23-75-58.ec2.internal (executor 1) (262/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 357.0 in stage 2.0 (TID 869, ip-172-23-75-58.ec2.internal, executor 1, partition 357, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 358.0 in stage 2.0 (TID 870, ip-172-23-70-80.ec2.internal, executor 2, partition 358, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 274.0 in stage 2.0 (TID 786) in 70 ms on ip-172-23-70-80.ec2.internal (executor 2) (263/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 359.0 in stage 2.0 (TID 871, ip-172-23-70-80.ec2.internal, executor 2, partition 359, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 360.0 in stage 2.0 (TID 872, ip-172-23-70-80.ec2.internal, executor 2, partition 360, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 261.0 in stage 2.0 (TID 773) in 79 ms on ip-172-23-70-80.ec2.internal (executor 2) (264/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 264.0 in stage 2.0 (TID 776) in 78 ms on ip-172-23-70-80.ec2.internal (executor 2) (265/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 258.0 in stage 2.0 (TID 770) in 83 ms on ip-172-23-70-80.ec2.internal (executor 2) (266/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 361.0 in stage 2.0 (TID 873, ip-172-23-70-80.ec2.internal, executor 2, partition 361, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 362.0 in stage 2.0 (TID 874, ip-172-23-70-80.ec2.internal, executor 2, partition 362, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 259.0 in stage 2.0 (TID 771) in 84 ms on ip-172-23-70-80.ec2.internal (executor 2) (267/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 266.0 in stage 2.0 (TID 778) in 77 ms on ip-172-23-70-80.ec2.internal (executor 2) (268/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 363.0 in stage 2.0 (TID 875, ip-172-23-70-80.ec2.internal, executor 2, partition 363, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 269.0 in stage 2.0 (TID 781) in 75 ms on ip-172-23-70-80.ec2.internal (executor 2) (269/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 364.0 in stage 2.0 (TID 876, ip-172-23-70-80.ec2.internal, executor 2, partition 364, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 270.0 in stage 2.0 (TID 782) in 75 ms on ip-172-23-70-80.ec2.internal (executor 2) (270/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 365.0 in stage 2.0 (TID 877, ip-172-23-70-80.ec2.internal, executor 2, partition 365, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 366.0 in stage 2.0 (TID 878, ip-172-23-70-80.ec2.internal, executor 2, partition 366, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 283.0 in stage 2.0 (TID 795) in 64 ms on ip-172-23-70-80.ec2.internal (executor 2) (271/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 284.0 in stage 2.0 (TID 796) in 64 ms on ip-172-23-75-58.ec2.internal (executor 1) (272/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 367.0 in stage 2.0 (TID 879, ip-172-23-75-58.ec2.internal, executor 1, partition 367, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 277.0 in stage 2.0 (TID 789) in 73 ms on ip-172-23-70-80.ec2.internal (executor 2) (273/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 368.0 in stage 2.0 (TID 880, ip-172-23-70-80.ec2.internal, executor 2, partition 368, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 281.0 in stage 2.0 (TID 793) in 66 ms on ip-172-23-75-58.ec2.internal (executor 1) (274/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 369.0 in stage 2.0 (TID 881, ip-172-23-75-58.ec2.internal, executor 1, partition 369, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 370.0 in stage 2.0 (TID 882, ip-172-23-70-80.ec2.internal, executor 2, partition 370, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 275.0 in stage 2.0 (TID 787) in 75 ms on ip-172-23-70-80.ec2.internal (executor 2) (275/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 265.0 in stage 2.0 (TID 777) in 85 ms on ip-172-23-70-80.ec2.internal (executor 2) (276/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 371.0 in stage 2.0 (TID 883, ip-172-23-70-80.ec2.internal, executor 2, partition 371, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 221.0 in stage 2.0 (TID 733) in 127 ms on ip-172-23-75-58.ec2.internal (executor 1) (277/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 372.0 in stage 2.0 (TID 884, ip-172-23-75-58.ec2.internal, executor 1, partition 372, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 291.0 in stage 2.0 (TID 803) in 64 ms on ip-172-23-75-58.ec2.internal (executor 1) (278/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 373.0 in stage 2.0 (TID 885, ip-172-23-75-58.ec2.internal, executor 1, partition 373, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 374.0 in stage 2.0 (TID 886, ip-172-23-75-58.ec2.internal, executor 1, partition 374, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 285.0 in stage 2.0 (TID 797) in 68 ms on ip-172-23-75-58.ec2.internal (executor 1) (279/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 278.0 in stage 2.0 (TID 790) in 78 ms on ip-172-23-70-80.ec2.internal (executor 2) (280/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 375.0 in stage 2.0 (TID 887, ip-172-23-70-80.ec2.internal, executor 2, partition 375, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 282.0 in stage 2.0 (TID 794) in 72 ms on ip-172-23-70-80.ec2.internal (executor 2) (281/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 376.0 in stage 2.0 (TID 888, ip-172-23-70-80.ec2.internal, executor 2, partition 376, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 298.0 in stage 2.0 (TID 810) in 61 ms on ip-172-23-70-80.ec2.internal (executor 2) (282/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 377.0 in stage 2.0 (TID 889, ip-172-23-70-80.ec2.internal, executor 2, partition 377, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 378.0 in stage 2.0 (TID 890, ip-172-23-70-80.ec2.internal, executor 2, partition 378, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 280.0 in stage 2.0 (TID 792) in 78 ms on ip-172-23-70-80.ec2.internal (executor 2) (283/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 287.0 in stage 2.0 (TID 799) in 68 ms on ip-172-23-70-80.ec2.internal (executor 2) (284/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 379.0 in stage 2.0 (TID 891, ip-172-23-70-80.ec2.internal, executor 2, partition 379, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 299.0 in stage 2.0 (TID 811) in 62 ms on ip-172-23-70-80.ec2.internal (executor 2) (285/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 380.0 in stage 2.0 (TID 892, ip-172-23-70-80.ec2.internal, executor 2, partition 380, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 294.0 in stage 2.0 (TID 806) in 65 ms on ip-172-23-70-80.ec2.internal (executor 2) (286/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 381.0 in stage 2.0 (TID 893, ip-172-23-70-80.ec2.internal, executor 2, partition 381, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 382.0 in stage 2.0 (TID 894, ip-172-23-75-58.ec2.internal, executor 1, partition 382, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 303.0 in stage 2.0 (TID 815) in 59 ms on ip-172-23-75-58.ec2.internal (executor 1) (287/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 313.0 in stage 2.0 (TID 825) in 54 ms on ip-172-23-75-58.ec2.internal (executor 1) (288/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 383.0 in stage 2.0 (TID 895, ip-172-23-75-58.ec2.internal, executor 1, partition 383, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 306.0 in stage 2.0 (TID 818) in 59 ms on ip-172-23-75-58.ec2.internal (executor 1) (289/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 384.0 in stage 2.0 (TID 896, ip-172-23-75-58.ec2.internal, executor 1, partition 384, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 301.0 in stage 2.0 (TID 813) in 62 ms on ip-172-23-75-58.ec2.internal (executor 1) (290/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 385.0 in stage 2.0 (TID 897, ip-172-23-75-58.ec2.internal, executor 1, partition 385, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 386.0 in stage 2.0 (TID 898, ip-172-23-75-58.ec2.internal, executor 1, partition 386, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 300.0 in stage 2.0 (TID 812) in 64 ms on ip-172-23-75-58.ec2.internal (executor 1) (291/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 302.0 in stage 2.0 (TID 814) in 65 ms on ip-172-23-75-58.ec2.internal (executor 1) (292/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 387.0 in stage 2.0 (TID 899, ip-172-23-75-58.ec2.internal, executor 1, partition 387, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 304.0 in stage 2.0 (TID 816) in 65 ms on ip-172-23-75-58.ec2.internal (executor 1) (293/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 388.0 in stage 2.0 (TID 900, ip-172-23-75-58.ec2.internal, executor 1, partition 388, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 315.0 in stage 2.0 (TID 827) in 60 ms on ip-172-23-70-80.ec2.internal (executor 2) (294/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 389.0 in stage 2.0 (TID 901, ip-172-23-70-80.ec2.internal, executor 2, partition 389, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 390.0 in stage 2.0 (TID 902, ip-172-23-75-58.ec2.internal, executor 1, partition 390, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 293.0 in stage 2.0 (TID 805) in 73 ms on ip-172-23-75-58.ec2.internal (executor 1) (295/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 312.0 in stage 2.0 (TID 824) in 62 ms on ip-172-23-75-58.ec2.internal (executor 1) (296/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 391.0 in stage 2.0 (TID 903, ip-172-23-75-58.ec2.internal, executor 1, partition 391, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 289.0 in stage 2.0 (TID 801) in 77 ms on ip-172-23-70-80.ec2.internal (executor 2) (297/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 392.0 in stage 2.0 (TID 904, ip-172-23-70-80.ec2.internal, executor 2, partition 392, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 297.0 in stage 2.0 (TID 809) in 73 ms on ip-172-23-70-80.ec2.internal (executor 2) (298/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 393.0 in stage 2.0 (TID 905, ip-172-23-70-80.ec2.internal, executor 2, partition 393, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 394.0 in stage 2.0 (TID 906, ip-172-23-70-80.ec2.internal, executor 2, partition 394, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 296.0 in stage 2.0 (TID 808) in 73 ms on ip-172-23-70-80.ec2.internal (executor 2) (299/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 318.0 in stage 2.0 (TID 830) in 60 ms on ip-172-23-75-58.ec2.internal (executor 1) (300/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 395.0 in stage 2.0 (TID 907, ip-172-23-75-58.ec2.internal, executor 1, partition 395, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 328.0 in stage 2.0 (TID 840) in 51 ms on ip-172-23-70-80.ec2.internal (executor 2) (301/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 396.0 in stage 2.0 (TID 908, ip-172-23-70-80.ec2.internal, executor 2, partition 396, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 311.0 in stage 2.0 (TID 823) in 65 ms on ip-172-23-70-80.ec2.internal (executor 2) (302/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 397.0 in stage 2.0 (TID 909, ip-172-23-70-80.ec2.internal, executor 2, partition 397, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 398.0 in stage 2.0 (TID 910, ip-172-23-70-80.ec2.internal, executor 2, partition 398, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 305.0 in stage 2.0 (TID 817) in 71 ms on ip-172-23-70-80.ec2.internal (executor 2) (303/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 399.0 in stage 2.0 (TID 911, ip-172-23-70-80.ec2.internal, executor 2, partition 399, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 290.0 in stage 2.0 (TID 802) in 80 ms on ip-172-23-70-80.ec2.internal (executor 2) (304/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 295.0 in stage 2.0 (TID 807) in 77 ms on ip-172-23-75-58.ec2.internal (executor 1) (305/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 400.0 in stage 2.0 (TID 912, ip-172-23-75-58.ec2.internal, executor 1, partition 400, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 317.0 in stage 2.0 (TID 829) in 64 ms on ip-172-23-75-58.ec2.internal (executor 1) (306/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 401.0 in stage 2.0 (TID 913, ip-172-23-75-58.ec2.internal, executor 1, partition 401, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 319.0 in stage 2.0 (TID 831) in 64 ms on ip-172-23-75-58.ec2.internal (executor 1) (307/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 402.0 in stage 2.0 (TID 914, ip-172-23-75-58.ec2.internal, executor 1, partition 402, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 403.0 in stage 2.0 (TID 915, ip-172-23-70-80.ec2.internal, executor 2, partition 403, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 307.0 in stage 2.0 (TID 819) in 73 ms on ip-172-23-70-80.ec2.internal (executor 2) (308/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 314.0 in stage 2.0 (TID 826) in 69 ms on ip-172-23-75-58.ec2.internal (executor 1) (309/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 404.0 in stage 2.0 (TID 916, ip-172-23-75-58.ec2.internal, executor 1, partition 404, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 316.0 in stage 2.0 (TID 828) in 68 ms on ip-172-23-75-58.ec2.internal (executor 1) (310/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 405.0 in stage 2.0 (TID 917, ip-172-23-75-58.ec2.internal, executor 1, partition 405, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 321.0 in stage 2.0 (TID 833) in 62 ms on ip-172-23-75-58.ec2.internal (executor 1) (311/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 406.0 in stage 2.0 (TID 918, ip-172-23-75-58.ec2.internal, executor 1, partition 406, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 407.0 in stage 2.0 (TID 919, ip-172-23-75-58.ec2.internal, executor 1, partition 407, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 320.0 in stage 2.0 (TID 832) in 62 ms on ip-172-23-75-58.ec2.internal (executor 1) (312/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 326.0 in stage 2.0 (TID 838) in 59 ms on ip-172-23-75-58.ec2.internal (executor 1) (313/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 408.0 in stage 2.0 (TID 920, ip-172-23-75-58.ec2.internal, executor 1, partition 408, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 323.0 in stage 2.0 (TID 835) in 63 ms on ip-172-23-75-58.ec2.internal (executor 1) (314/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 409.0 in stage 2.0 (TID 921, ip-172-23-75-58.ec2.internal, executor 1, partition 409, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 322.0 in stage 2.0 (TID 834) in 65 ms on ip-172-23-75-58.ec2.internal (executor 1) (315/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 410.0 in stage 2.0 (TID 922, ip-172-23-75-58.ec2.internal, executor 1, partition 410, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 411.0 in stage 2.0 (TID 923, ip-172-23-75-58.ec2.internal, executor 1, partition 411, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 327.0 in stage 2.0 (TID 839) in 62 ms on ip-172-23-75-58.ec2.internal (executor 1) (316/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 329.0 in stage 2.0 (TID 841) in 61 ms on ip-172-23-75-58.ec2.internal (executor 1) (317/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 412.0 in stage 2.0 (TID 924, ip-172-23-75-58.ec2.internal, executor 1, partition 412, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 413.0 in stage 2.0 (TID 925, ip-172-23-75-58.ec2.internal, executor 1, partition 413, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 324.0 in stage 2.0 (TID 836) in 68 ms on ip-172-23-75-58.ec2.internal (executor 1) (318/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 414.0 in stage 2.0 (TID 926, ip-172-23-75-58.ec2.internal, executor 1, partition 414, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 330.0 in stage 2.0 (TID 842) in 66 ms on ip-172-23-75-58.ec2.internal (executor 1) (319/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 415.0 in stage 2.0 (TID 927, ip-172-23-70-80.ec2.internal, executor 2, partition 415, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 345.0 in stage 2.0 (TID 857) in 56 ms on ip-172-23-70-80.ec2.internal (executor 2) (320/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 416.0 in stage 2.0 (TID 928, ip-172-23-75-58.ec2.internal, executor 1, partition 416, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 325.0 in stage 2.0 (TID 837) in 70 ms on ip-172-23-75-58.ec2.internal (executor 1) (321/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 417.0 in stage 2.0 (TID 929, ip-172-23-70-80.ec2.internal, executor 2, partition 417, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 332.0 in stage 2.0 (TID 844) in 66 ms on ip-172-23-70-80.ec2.internal (executor 2) (322/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 418.0 in stage 2.0 (TID 930, ip-172-23-75-58.ec2.internal, executor 1, partition 418, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 337.0 in stage 2.0 (TID 849) in 65 ms on ip-172-23-75-58.ec2.internal (executor 1) (323/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 419.0 in stage 2.0 (TID 931, ip-172-23-75-58.ec2.internal, executor 1, partition 419, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 336.0 in stage 2.0 (TID 848) in 66 ms on ip-172-23-75-58.ec2.internal (executor 1) (324/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 420.0 in stage 2.0 (TID 932, ip-172-23-75-58.ec2.internal, executor 1, partition 420, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 338.0 in stage 2.0 (TID 850) in 67 ms on ip-172-23-75-58.ec2.internal (executor 1) (325/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 421.0 in stage 2.0 (TID 933, ip-172-23-75-58.ec2.internal, executor 1, partition 421, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 422.0 in stage 2.0 (TID 934, ip-172-23-75-58.ec2.internal, executor 1, partition 422, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 350.0 in stage 2.0 (TID 862) in 61 ms on ip-172-23-75-58.ec2.internal (executor 1) (326/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 346.0 in stage 2.0 (TID 858) in 64 ms on ip-172-23-75-58.ec2.internal (executor 1) (327/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 423.0 in stage 2.0 (TID 935, ip-172-23-75-58.ec2.internal, executor 1, partition 423, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 351.0 in stage 2.0 (TID 863) in 62 ms on ip-172-23-75-58.ec2.internal (executor 1) (328/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 424.0 in stage 2.0 (TID 936, ip-172-23-75-58.ec2.internal, executor 1, partition 424, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 348.0 in stage 2.0 (TID 860) in 65 ms on ip-172-23-75-58.ec2.internal (executor 1) (329/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 425.0 in stage 2.0 (TID 937, ip-172-23-75-58.ec2.internal, executor 1, partition 425, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 339.0 in stage 2.0 (TID 851) in 71 ms on ip-172-23-75-58.ec2.internal (executor 1) (330/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 426.0 in stage 2.0 (TID 938, ip-172-23-75-58.ec2.internal, executor 1, partition 426, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 349.0 in stage 2.0 (TID 861) in 66 ms on ip-172-23-75-58.ec2.internal (executor 1) (331/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 427.0 in stage 2.0 (TID 939, ip-172-23-75-58.ec2.internal, executor 1, partition 427, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 428.0 in stage 2.0 (TID 940, ip-172-23-75-58.ec2.internal, executor 1, partition 428, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 331.0 in stage 2.0 (TID 843) in 79 ms on ip-172-23-75-58.ec2.internal (executor 1) (332/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 347.0 in stage 2.0 (TID 859) in 69 ms on ip-172-23-75-58.ec2.internal (executor 1) (333/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 429.0 in stage 2.0 (TID 941, ip-172-23-75-58.ec2.internal, executor 1, partition 429, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 355.0 in stage 2.0 (TID 867) in 64 ms on ip-172-23-75-58.ec2.internal (executor 1) (334/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 430.0 in stage 2.0 (TID 942, ip-172-23-75-58.ec2.internal, executor 1, partition 430, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 342.0 in stage 2.0 (TID 854) in 75 ms on ip-172-23-75-58.ec2.internal (executor 1) (335/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 431.0 in stage 2.0 (TID 943, ip-172-23-75-58.ec2.internal, executor 1, partition 431, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 354.0 in stage 2.0 (TID 866) in 68 ms on ip-172-23-75-58.ec2.internal (executor 1) (336/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 432.0 in stage 2.0 (TID 944, ip-172-23-75-58.ec2.internal, executor 1, partition 432, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 356.0 in stage 2.0 (TID 868) in 66 ms on ip-172-23-75-58.ec2.internal (executor 1) (337/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 433.0 in stage 2.0 (TID 945, ip-172-23-75-58.ec2.internal, executor 1, partition 433, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 340.0 in stage 2.0 (TID 852) in 79 ms on ip-172-23-75-58.ec2.internal (executor 1) (338/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 434.0 in stage 2.0 (TID 946, ip-172-23-75-58.ec2.internal, executor 1, partition 434, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 341.0 in stage 2.0 (TID 853) in 78 ms on ip-172-23-75-58.ec2.internal (executor 1) (339/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 435.0 in stage 2.0 (TID 947, ip-172-23-75-58.ec2.internal, executor 1, partition 435, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 357.0 in stage 2.0 (TID 869) in 64 ms on ip-172-23-75-58.ec2.internal (executor 1) (340/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 436.0 in stage 2.0 (TID 948, ip-172-23-75-58.ec2.internal, executor 1, partition 436, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 367.0 in stage 2.0 (TID 879) in 60 ms on ip-172-23-75-58.ec2.internal (executor 1) (341/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 437.0 in stage 2.0 (TID 949, ip-172-23-70-80.ec2.internal, executor 2, partition 437, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 333.0 in stage 2.0 (TID 845) in 86 ms on ip-172-23-70-80.ec2.internal (executor 2) (342/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 438.0 in stage 2.0 (TID 950, ip-172-23-70-80.ec2.internal, executor 2, partition 438, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 343.0 in stage 2.0 (TID 855) in 81 ms on ip-172-23-70-80.ec2.internal (executor 2) (343/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 439.0 in stage 2.0 (TID 951, ip-172-23-70-80.ec2.internal, executor 2, partition 439, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 310.0 in stage 2.0 (TID 822) in 108 ms on ip-172-23-70-80.ec2.internal (executor 2) (344/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 440.0 in stage 2.0 (TID 952, ip-172-23-75-58.ec2.internal, executor 1, partition 440, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 369.0 in stage 2.0 (TID 881) in 62 ms on ip-172-23-75-58.ec2.internal (executor 1) (345/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 441.0 in stage 2.0 (TID 953, ip-172-23-70-80.ec2.internal, executor 2, partition 441, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 370.0 in stage 2.0 (TID 882) in 63 ms on ip-172-23-70-80.ec2.internal (executor 2) (346/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 442.0 in stage 2.0 (TID 954, ip-172-23-70-80.ec2.internal, executor 2, partition 442, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 443.0 in stage 2.0 (TID 955, ip-172-23-70-80.ec2.internal, executor 2, partition 443, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 344.0 in stage 2.0 (TID 856) in 84 ms on ip-172-23-70-80.ec2.internal (executor 2) (347/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 309.0 in stage 2.0 (TID 821) in 111 ms on ip-172-23-70-80.ec2.internal (executor 2) (348/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 444.0 in stage 2.0 (TID 956, ip-172-23-70-80.ec2.internal, executor 2, partition 444, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 352.0 in stage 2.0 (TID 864) in 81 ms on ip-172-23-70-80.ec2.internal (executor 2) (349/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 445.0 in stage 2.0 (TID 957, ip-172-23-70-80.ec2.internal, executor 2, partition 445, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 292.0 in stage 2.0 (TID 804) in 126 ms on ip-172-23-70-80.ec2.internal (executor 2) (350/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 446.0 in stage 2.0 (TID 958, ip-172-23-70-80.ec2.internal, executor 2, partition 446, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 359.0 in stage 2.0 (TID 871) in 73 ms on ip-172-23-70-80.ec2.internal (executor 2) (351/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 447.0 in stage 2.0 (TID 959, ip-172-23-70-80.ec2.internal, executor 2, partition 447, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 362.0 in stage 2.0 (TID 874) in 73 ms on ip-172-23-70-80.ec2.internal (executor 2) (352/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 448.0 in stage 2.0 (TID 960, ip-172-23-70-80.ec2.internal, executor 2, partition 448, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 335.0 in stage 2.0 (TID 847) in 94 ms on ip-172-23-70-80.ec2.internal (executor 2) (353/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 449.0 in stage 2.0 (TID 961, ip-172-23-70-80.ec2.internal, executor 2, partition 449, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 353.0 in stage 2.0 (TID 865) in 83 ms on ip-172-23-70-80.ec2.internal (executor 2) (354/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 450.0 in stage 2.0 (TID 962, ip-172-23-70-80.ec2.internal, executor 2, partition 450, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 361.0 in stage 2.0 (TID 873) in 75 ms on ip-172-23-70-80.ec2.internal (executor 2) (355/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 451.0 in stage 2.0 (TID 963, ip-172-23-70-80.ec2.internal, executor 2, partition 451, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 288.0 in stage 2.0 (TID 800) in 132 ms on ip-172-23-70-80.ec2.internal (executor 2) (356/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 452.0 in stage 2.0 (TID 964, ip-172-23-70-80.ec2.internal, executor 2, partition 452, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 453.0 in stage 2.0 (TID 965, ip-172-23-70-80.ec2.internal, executor 2, partition 453, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 377.0 in stage 2.0 (TID 889) in 66 ms on ip-172-23-70-80.ec2.internal (executor 2) (357/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 376.0 in stage 2.0 (TID 888) in 67 ms on ip-172-23-70-80.ec2.internal (executor 2) (358/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 454.0 in stage 2.0 (TID 966, ip-172-23-70-80.ec2.internal, executor 2, partition 454, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 455.0 in stage 2.0 (TID 967, ip-172-23-70-80.ec2.internal, executor 2, partition 455, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 456.0 in stage 2.0 (TID 968, ip-172-23-70-80.ec2.internal, executor 2, partition 456, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 365.0 in stage 2.0 (TID 877) in 77 ms on ip-172-23-70-80.ec2.internal (executor 2) (359/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 375.0 in stage 2.0 (TID 887) in 69 ms on ip-172-23-70-80.ec2.internal (executor 2) (360/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 334.0 in stage 2.0 (TID 846) in 100 ms on ip-172-23-70-80.ec2.internal (executor 2) (361/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 457.0 in stage 2.0 (TID 969, ip-172-23-75-58.ec2.internal, executor 1, partition 457, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 395.0 in stage 2.0 (TID 907) in 57 ms on ip-172-23-75-58.ec2.internal (executor 1) (362/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 458.0 in stage 2.0 (TID 970, ip-172-23-75-58.ec2.internal, executor 1, partition 458, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 459.0 in stage 2.0 (TID 971, ip-172-23-75-58.ec2.internal, executor 1, partition 459, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 404.0 in stage 2.0 (TID 916) in 53 ms on ip-172-23-75-58.ec2.internal (executor 1) (363/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 400.0 in stage 2.0 (TID 912) in 56 ms on ip-172-23-75-58.ec2.internal (executor 1) (364/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 460.0 in stage 2.0 (TID 972, ip-172-23-75-58.ec2.internal, executor 1, partition 460, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 461.0 in stage 2.0 (TID 973, ip-172-23-75-58.ec2.internal, executor 1, partition 461, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 390.0 in stage 2.0 (TID 902) in 63 ms on ip-172-23-75-58.ec2.internal (executor 1) (365/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 402.0 in stage 2.0 (TID 914) in 57 ms on ip-172-23-75-58.ec2.internal (executor 1) (366/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 462.0 in stage 2.0 (TID 974, ip-172-23-75-58.ec2.internal, executor 1, partition 462, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 463.0 in stage 2.0 (TID 975, ip-172-23-75-58.ec2.internal, executor 1, partition 463, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 405.0 in stage 2.0 (TID 917) in 56 ms on ip-172-23-75-58.ec2.internal (executor 1) (367/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 388.0 in stage 2.0 (TID 900) in 66 ms on ip-172-23-75-58.ec2.internal (executor 1) (368/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 464.0 in stage 2.0 (TID 976, ip-172-23-75-58.ec2.internal, executor 1, partition 464, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 401.0 in stage 2.0 (TID 913) in 60 ms on ip-172-23-75-58.ec2.internal (executor 1) (369/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 465.0 in stage 2.0 (TID 977, ip-172-23-75-58.ec2.internal, executor 1, partition 465, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 391.0 in stage 2.0 (TID 903) in 65 ms on ip-172-23-75-58.ec2.internal (executor 1) (370/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 466.0 in stage 2.0 (TID 978, ip-172-23-70-80.ec2.internal, executor 2, partition 466, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 358.0 in stage 2.0 (TID 870) in 88 ms on ip-172-23-70-80.ec2.internal (executor 2) (371/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 467.0 in stage 2.0 (TID 979, ip-172-23-75-58.ec2.internal, executor 1, partition 467, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 383.0 in stage 2.0 (TID 895) in 73 ms on ip-172-23-75-58.ec2.internal (executor 1) (372/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 468.0 in stage 2.0 (TID 980, ip-172-23-75-58.ec2.internal, executor 1, partition 468, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 385.0 in stage 2.0 (TID 897) in 73 ms on ip-172-23-75-58.ec2.internal (executor 1) (373/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 469.0 in stage 2.0 (TID 981, ip-172-23-75-58.ec2.internal, executor 1, partition 469, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 386.0 in stage 2.0 (TID 898) in 73 ms on ip-172-23-75-58.ec2.internal (executor 1) (374/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 470.0 in stage 2.0 (TID 982, ip-172-23-75-58.ec2.internal, executor 1, partition 470, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 384.0 in stage 2.0 (TID 896) in 75 ms on ip-172-23-75-58.ec2.internal (executor 1) (375/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 471.0 in stage 2.0 (TID 983, ip-172-23-75-58.ec2.internal, executor 1, partition 471, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 372.0 in stage 2.0 (TID 884) in 80 ms on ip-172-23-75-58.ec2.internal (executor 1) (376/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 472.0 in stage 2.0 (TID 984, ip-172-23-75-58.ec2.internal, executor 1, partition 472, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 374.0 in stage 2.0 (TID 886) in 81 ms on ip-172-23-75-58.ec2.internal (executor 1) (377/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 473.0 in stage 2.0 (TID 985, ip-172-23-75-58.ec2.internal, executor 1, partition 473, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 382.0 in stage 2.0 (TID 894) in 78 ms on ip-172-23-75-58.ec2.internal (executor 1) (378/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 474.0 in stage 2.0 (TID 986, ip-172-23-75-58.ec2.internal, executor 1, partition 474, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 373.0 in stage 2.0 (TID 885) in 82 ms on ip-172-23-75-58.ec2.internal (executor 1) (379/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 475.0 in stage 2.0 (TID 987, ip-172-23-75-58.ec2.internal, executor 1, partition 475, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 408.0 in stage 2.0 (TID 920) in 61 ms on ip-172-23-75-58.ec2.internal (executor 1) (380/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 476.0 in stage 2.0 (TID 988, ip-172-23-75-58.ec2.internal, executor 1, partition 476, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 410.0 in stage 2.0 (TID 922) in 58 ms on ip-172-23-75-58.ec2.internal (executor 1) (381/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 477.0 in stage 2.0 (TID 989, ip-172-23-75-58.ec2.internal, executor 1, partition 477, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 406.0 in stage 2.0 (TID 918) in 63 ms on ip-172-23-75-58.ec2.internal (executor 1) (382/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 478.0 in stage 2.0 (TID 990, ip-172-23-75-58.ec2.internal, executor 1, partition 478, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 411.0 in stage 2.0 (TID 923) in 60 ms on ip-172-23-75-58.ec2.internal (executor 1) (383/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 479.0 in stage 2.0 (TID 991, ip-172-23-70-80.ec2.internal, executor 2, partition 479, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 381.0 in stage 2.0 (TID 893) in 81 ms on ip-172-23-70-80.ec2.internal (executor 2) (384/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 480.0 in stage 2.0 (TID 992, ip-172-23-75-58.ec2.internal, executor 1, partition 480, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 481.0 in stage 2.0 (TID 993, ip-172-23-70-80.ec2.internal, executor 2, partition 481, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 378.0 in stage 2.0 (TID 890) in 84 ms on ip-172-23-70-80.ec2.internal (executor 2) (385/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 412.0 in stage 2.0 (TID 924) in 61 ms on ip-172-23-75-58.ec2.internal (executor 1) (386/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 482.0 in stage 2.0 (TID 994, ip-172-23-75-58.ec2.internal, executor 1, partition 482, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 409.0 in stage 2.0 (TID 921) in 64 ms on ip-172-23-75-58.ec2.internal (executor 1) (387/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 483.0 in stage 2.0 (TID 995, ip-172-23-70-80.ec2.internal, executor 2, partition 483, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 368.0 in stage 2.0 (TID 880) in 94 ms on ip-172-23-70-80.ec2.internal (executor 2) (388/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 484.0 in stage 2.0 (TID 996, ip-172-23-70-80.ec2.internal, executor 2, partition 484, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 379.0 in stage 2.0 (TID 891) in 85 ms on ip-172-23-70-80.ec2.internal (executor 2) (389/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 485.0 in stage 2.0 (TID 997, ip-172-23-70-80.ec2.internal, executor 2, partition 485, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 380.0 in stage 2.0 (TID 892) in 86 ms on ip-172-23-70-80.ec2.internal (executor 2) (390/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 486.0 in stage 2.0 (TID 998, ip-172-23-70-80.ec2.internal, executor 2, partition 486, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 392.0 in stage 2.0 (TID 904) in 77 ms on ip-172-23-70-80.ec2.internal (executor 2) (391/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 487.0 in stage 2.0 (TID 999, ip-172-23-70-80.ec2.internal, executor 2, partition 487, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 399.0 in stage 2.0 (TID 911) in 74 ms on ip-172-23-70-80.ec2.internal (executor 2) (392/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 488.0 in stage 2.0 (TID 1000, ip-172-23-75-58.ec2.internal, executor 1, partition 488, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 413.0 in stage 2.0 (TID 925) in 62 ms on ip-172-23-75-58.ec2.internal (executor 1) (393/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 489.0 in stage 2.0 (TID 1001, ip-172-23-75-58.ec2.internal, executor 1, partition 489, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 414.0 in stage 2.0 (TID 926) in 62 ms on ip-172-23-75-58.ec2.internal (executor 1) (394/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 490.0 in stage 2.0 (TID 1002, ip-172-23-70-80.ec2.internal, executor 2, partition 490, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 417.0 in stage 2.0 (TID 929) in 58 ms on ip-172-23-70-80.ec2.internal (executor 2) (395/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 491.0 in stage 2.0 (TID 1003, ip-172-23-75-58.ec2.internal, executor 1, partition 491, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 416.0 in stage 2.0 (TID 928) in 60 ms on ip-172-23-75-58.ec2.internal (executor 1) (396/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 492.0 in stage 2.0 (TID 1004, ip-172-23-70-80.ec2.internal, executor 2, partition 492, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 389.0 in stage 2.0 (TID 901) in 82 ms on ip-172-23-70-80.ec2.internal (executor 2) (397/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 493.0 in stage 2.0 (TID 1005, ip-172-23-75-58.ec2.internal, executor 1, partition 493, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 418.0 in stage 2.0 (TID 930) in 59 ms on ip-172-23-75-58.ec2.internal (executor 1) (398/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 494.0 in stage 2.0 (TID 1006, ip-172-23-70-80.ec2.internal, executor 2, partition 494, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 393.0 in stage 2.0 (TID 905) in 82 ms on ip-172-23-70-80.ec2.internal (executor 2) (399/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 495.0 in stage 2.0 (TID 1007, ip-172-23-75-58.ec2.internal, executor 1, partition 495, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 421.0 in stage 2.0 (TID 933) in 56 ms on ip-172-23-75-58.ec2.internal (executor 1) (400/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 496.0 in stage 2.0 (TID 1008, ip-172-23-70-80.ec2.internal, executor 2, partition 496, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 394.0 in stage 2.0 (TID 906) in 83 ms on ip-172-23-70-80.ec2.internal (executor 2) (401/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 497.0 in stage 2.0 (TID 1009, ip-172-23-75-58.ec2.internal, executor 1, partition 497, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 419.0 in stage 2.0 (TID 931) in 61 ms on ip-172-23-75-58.ec2.internal (executor 1) (402/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 498.0 in stage 2.0 (TID 1010, ip-172-23-75-58.ec2.internal, executor 1, partition 498, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 420.0 in stage 2.0 (TID 932) in 59 ms on ip-172-23-75-58.ec2.internal (executor 1) (403/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Starting task 499.0 in stage 2.0 (TID 1011, ip-172-23-75-58.ec2.internal, executor 1, partition 499, PROCESS_LOCAL, 8165 bytes) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 422.0 in stage 2.0 (TID 934) in 58 ms on ip-172-23-75-58.ec2.internal (executor 1) (404/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 430.0 in stage 2.0 (TID 942) in 50 ms on ip-172-23-75-58.ec2.internal (executor 1) (405/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 425.0 in stage 2.0 (TID 937) in 55 ms on ip-172-23-75-58.ec2.internal (executor 1) (406/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 434.0 in stage 2.0 (TID 946) in 47 ms on ip-172-23-75-58.ec2.internal (executor 1) (407/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 396.0 in stage 2.0 (TID 908) in 84 ms on ip-172-23-70-80.ec2.internal (executor 2) (408/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 428.0 in stage 2.0 (TID 940) in 52 ms on ip-172-23-75-58.ec2.internal (executor 1) (409/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 424.0 in stage 2.0 (TID 936) in 58 ms on ip-172-23-75-58.ec2.internal (executor 1) (410/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 440.0 in stage 2.0 (TID 952) in 44 ms on ip-172-23-75-58.ec2.internal (executor 1) (411/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 438.0 in stage 2.0 (TID 950) in 46 ms on ip-172-23-70-80.ec2.internal (executor 2) (412/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 432.0 in stage 2.0 (TID 944) in 50 ms on ip-172-23-75-58.ec2.internal (executor 1) (413/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 433.0 in stage 2.0 (TID 945) in 50 ms on ip-172-23-75-58.ec2.internal (executor 1) (414/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 364.0 in stage 2.0 (TID 876) in 109 ms on ip-172-23-70-80.ec2.internal (executor 2) (415/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 431.0 in stage 2.0 (TID 943) in 52 ms on ip-172-23-75-58.ec2.internal (executor 1) (416/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 435.0 in stage 2.0 (TID 947) in 50 ms on ip-172-23-75-58.ec2.internal (executor 1) (417/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 452.0 in stage 2.0 (TID 964) in 36 ms on ip-172-23-70-80.ec2.internal (executor 2) (418/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 436.0 in stage 2.0 (TID 948) in 50 ms on ip-172-23-75-58.ec2.internal (executor 1) (419/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 445.0 in stage 2.0 (TID 957) in 43 ms on ip-172-23-70-80.ec2.internal (executor 2) (420/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 429.0 in stage 2.0 (TID 941) in 56 ms on ip-172-23-75-58.ec2.internal (executor 1) (421/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 426.0 in stage 2.0 (TID 938) in 59 ms on ip-172-23-75-58.ec2.internal (executor 1) (422/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 398.0 in stage 2.0 (TID 910) in 89 ms on ip-172-23-70-80.ec2.internal (executor 2) (423/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 387.0 in stage 2.0 (TID 899) in 95 ms on ip-172-23-75-58.ec2.internal (executor 1) (424/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 449.0 in stage 2.0 (TID 961) in 40 ms on ip-172-23-70-80.ec2.internal (executor 2) (425/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 427.0 in stage 2.0 (TID 939) in 59 ms on ip-172-23-75-58.ec2.internal (executor 1) (426/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 454.0 in stage 2.0 (TID 966) in 37 ms on ip-172-23-70-80.ec2.internal (executor 2) (427/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 441.0 in stage 2.0 (TID 953) in 48 ms on ip-172-23-70-80.ec2.internal (executor 2) (428/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 442.0 in stage 2.0 (TID 954) in 48 ms on ip-172-23-70-80.ec2.internal (executor 2) (429/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 407.0 in stage 2.0 (TID 919) in 86 ms on ip-172-23-75-58.ec2.internal (executor 1) (430/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 457.0 in stage 2.0 (TID 969) in 37 ms on ip-172-23-75-58.ec2.internal (executor 1) (431/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 459.0 in stage 2.0 (TID 971) in 35 ms on ip-172-23-75-58.ec2.internal (executor 1) (432/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 446.0 in stage 2.0 (TID 958) in 46 ms on ip-172-23-70-80.ec2.internal (executor 2) (433/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 448.0 in stage 2.0 (TID 960) in 44 ms on ip-172-23-70-80.ec2.internal (executor 2) (434/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 462.0 in stage 2.0 (TID 974) in 33 ms on ip-172-23-75-58.ec2.internal (executor 1) (435/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 423.0 in stage 2.0 (TID 935) in 66 ms on ip-172-23-75-58.ec2.internal (executor 1) (436/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 363.0 in stage 2.0 (TID 875) in 118 ms on ip-172-23-70-80.ec2.internal (executor 2) (437/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 455.0 in stage 2.0 (TID 967) in 41 ms on ip-172-23-70-80.ec2.internal (executor 2) (438/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 366.0 in stage 2.0 (TID 878) in 119 ms on ip-172-23-70-80.ec2.internal (executor 2) (439/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 443.0 in stage 2.0 (TID 955) in 54 ms on ip-172-23-70-80.ec2.internal (executor 2) (440/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 460.0 in stage 2.0 (TID 972) in 39 ms on ip-172-23-75-58.ec2.internal (executor 1) (441/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 461.0 in stage 2.0 (TID 973) in 39 ms on ip-172-23-75-58.ec2.internal (executor 1) (442/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 467.0 in stage 2.0 (TID 979) in 35 ms on ip-172-23-75-58.ec2.internal (executor 1) (443/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 458.0 in stage 2.0 (TID 970) in 41 ms on ip-172-23-75-58.ec2.internal (executor 1) (444/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 469.0 in stage 2.0 (TID 981) in 35 ms on ip-172-23-75-58.ec2.internal (executor 1) (445/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 456.0 in stage 2.0 (TID 968) in 44 ms on ip-172-23-70-80.ec2.internal (executor 2) (446/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 453.0 in stage 2.0 (TID 965) in 47 ms on ip-172-23-70-80.ec2.internal (executor 2) (447/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 439.0 in stage 2.0 (TID 951) in 59 ms on ip-172-23-70-80.ec2.internal (executor 2) (448/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 444.0 in stage 2.0 (TID 956) in 57 ms on ip-172-23-70-80.ec2.internal (executor 2) (449/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 468.0 in stage 2.0 (TID 980) in 38 ms on ip-172-23-75-58.ec2.internal (executor 1) (450/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 371.0 in stage 2.0 (TID 883) in 118 ms on ip-172-23-70-80.ec2.internal (executor 2) (451/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 465.0 in stage 2.0 (TID 977) in 41 ms on ip-172-23-75-58.ec2.internal (executor 1) (452/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 464.0 in stage 2.0 (TID 976) in 42 ms on ip-172-23-75-58.ec2.internal (executor 1) (453/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 451.0 in stage 2.0 (TID 963) in 51 ms on ip-172-23-70-80.ec2.internal (executor 2) (454/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 470.0 in stage 2.0 (TID 982) in 38 ms on ip-172-23-75-58.ec2.internal (executor 1) (455/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 415.0 in stage 2.0 (TID 927) in 87 ms on ip-172-23-70-80.ec2.internal (executor 2) (456/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 472.0 in stage 2.0 (TID 984) in 39 ms on ip-172-23-75-58.ec2.internal (executor 1) (457/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 473.0 in stage 2.0 (TID 985) in 39 ms on ip-172-23-75-58.ec2.internal (executor 1) (458/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 463.0 in stage 2.0 (TID 975) in 44 ms on ip-172-23-75-58.ec2.internal (executor 1) (459/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 479.0 in stage 2.0 (TID 991) in 37 ms on ip-172-23-70-80.ec2.internal (executor 2) (460/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 475.0 in stage 2.0 (TID 987) in 39 ms on ip-172-23-75-58.ec2.internal (executor 1) (461/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 485.0 in stage 2.0 (TID 997) in 33 ms on ip-172-23-70-80.ec2.internal (executor 2) (462/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 471.0 in stage 2.0 (TID 983) in 43 ms on ip-172-23-75-58.ec2.internal (executor 1) (463/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 474.0 in stage 2.0 (TID 986) in 42 ms on ip-172-23-75-58.ec2.internal (executor 1) (464/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 480.0 in stage 2.0 (TID 992) in 38 ms on ip-172-23-75-58.ec2.internal (executor 1) (465/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 476.0 in stage 2.0 (TID 988) in 41 ms on ip-172-23-75-58.ec2.internal (executor 1) (466/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 482.0 in stage 2.0 (TID 994) in 39 ms on ip-172-23-75-58.ec2.internal (executor 1) (467/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 488.0 in stage 2.0 (TID 1000) in 35 ms on ip-172-23-75-58.ec2.internal (executor 1) (468/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 478.0 in stage 2.0 (TID 990) in 42 ms on ip-172-23-75-58.ec2.internal (executor 1) (469/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 483.0 in stage 2.0 (TID 995) in 38 ms on ip-172-23-70-80.ec2.internal (executor 2) (470/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 477.0 in stage 2.0 (TID 989) in 42 ms on ip-172-23-75-58.ec2.internal (executor 1) (471/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 491.0 in stage 2.0 (TID 1003) in 36 ms on ip-172-23-75-58.ec2.internal (executor 1) (472/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 489.0 in stage 2.0 (TID 1001) in 38 ms on ip-172-23-75-58.ec2.internal (executor 1) (473/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 494.0 in stage 2.0 (TID 1006) in 36 ms on ip-172-23-70-80.ec2.internal (executor 2) (474/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 490.0 in stage 2.0 (TID 1002) in 38 ms on ip-172-23-70-80.ec2.internal (executor 2) (475/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 497.0 in stage 2.0 (TID 1009) in 34 ms on ip-172-23-75-58.ec2.internal (executor 1) (476/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 499.0 in stage 2.0 (TID 1011) in 34 ms on ip-172-23-75-58.ec2.internal (executor 1) (477/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 495.0 in stage 2.0 (TID 1007) in 37 ms on ip-172-23-75-58.ec2.internal (executor 1) (478/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 493.0 in stage 2.0 (TID 1005) in 39 ms on ip-172-23-75-58.ec2.internal (executor 1) (479/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 496.0 in stage 2.0 (TID 1008) in 37 ms on ip-172-23-70-80.ec2.internal (executor 2) (480/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 492.0 in stage 2.0 (TID 1004) in 43 ms on ip-172-23-70-80.ec2.internal (executor 2) (481/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 360.0 in stage 2.0 (TID 872) in 149 ms on ip-172-23-70-80.ec2.internal (executor 2) (482/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 466.0 in stage 2.0 (TID 978) in 62 ms on ip-172-23-70-80.ec2.internal (executor 2) (483/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 487.0 in stage 2.0 (TID 999) in 52 ms on ip-172-23-70-80.ec2.internal (executor 2) (484/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 450.0 in stage 2.0 (TID 962) in 85 ms on ip-172-23-70-80.ec2.internal (executor 2) (485/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 279.0 in stage 2.0 (TID 791) in 228 ms on ip-172-23-70-80.ec2.internal (executor 2) (486/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 481.0 in stage 2.0 (TID 993) in 66 ms on ip-172-23-70-80.ec2.internal (executor 2) (487/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 486.0 in stage 2.0 (TID 998) in 68 ms on ip-172-23-70-80.ec2.internal (executor 2) (488/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 437.0 in stage 2.0 (TID 949) in 102 ms on ip-172-23-70-80.ec2.internal (executor 2) (489/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 484.0 in stage 2.0 (TID 996) in 70 ms on ip-172-23-70-80.ec2.internal (executor 2) (490/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 498.0 in stage 2.0 (TID 1010) in 64 ms on ip-172-23-75-58.ec2.internal (executor 1) (491/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 272.0 in stage 2.0 (TID 784) in 268 ms on ip-172-23-70-80.ec2.internal (executor 2) (492/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 286.0 in stage 2.0 (TID 798) in 268 ms on ip-172-23-70-80.ec2.internal (executor 2) (493/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 114.0 in stage 2.0 (TID 626) in 463 ms on ip-172-23-70-80.ec2.internal (executor 2) (494/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 403.0 in stage 2.0 (TID 915) in 259 ms on ip-172-23-70-80.ec2.internal (executor 2) (495/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 397.0 in stage 2.0 (TID 909) in 267 ms on ip-172-23-70-80.ec2.internal (executor 2) (496/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 192.0 in stage 2.0 (TID 704) in 474 ms on ip-172-23-70-80.ec2.internal (executor 2) (497/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 271.0 in stage 2.0 (TID 783) in 479 ms on ip-172-23-70-80.ec2.internal (executor 2) (498/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 308.0 in stage 2.0 (TID 820) in 452 ms on ip-172-23-70-80.ec2.internal (executor 2) (499/500) 2022-04-01 03:25:20 TaskSetManager: INFO: Finished task 447.0 in stage 2.0 (TID 959) in 458 ms on ip-172-23-70-80.ec2.internal (executor 2) (500/500) 2022-04-01 03:25:20 YarnScheduler: INFO: Removed TaskSet 2.0, whose tasks have all completed, from pool 2022-04-01 03:25:20 DAGScheduler: INFO: ResultStage 2 (runJob at ContextRDD.scala:228) finished in 1.025 s 2022-04-01 03:25:20 DAGScheduler: INFO: Job 2 finished: runJob at ContextRDD.scala:228, took 1.031193 s 2022-04-01 03:25:20 Hail: INFO: Coerced almost-sorted dataset 2022-04-01 03:25:20 root: INFO: Unsorted keys: CURRENT={ locus: { contig: chr1, position: 92478757 }, alleles: [2; CAGAGAG, C] }, PREV={ locus: { contig: chr1, position: 92478757 }, alleles: [2; CAGAGAG, CAGAGAGAGAGAGAGAG] } 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.034ms, total 3.589s 2022-04-01 03:25:20 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 10: (Coalesce (InsertFields (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (a_index (I32 1)) (alleles_old (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1))) (locus_old (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.350ms, total 3.590s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.115ms, total 3.590s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.100ms, total 3.590s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 1.351ms, total 3.592s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.062ms, total 3.592s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.603ms, total 3.592s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 3.170ms, total 3.593s, tagged coverage 81.4 2022-04-01 03:25:20 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 10: (Coalesce (InsertFields (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (a_index (I32 1)) (alleles_old (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1))) (locus_old (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 4.255ms, total 3.593s, tagged coverage 60.7 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.035ms, total 3.593s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 4.702ms, total 3.593s, tagged coverage 56.4 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.061ms, total 3.594s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.055ms, total 3.594s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.024ms, total 3.594s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.370ms, total 3.594s, tagged coverage 37.8 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.007ms, total 3.594s 2022-04-01 03:25:20 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 10: (Coalesce (InsertFields (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (a_index (I32 1)) (alleles_old (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1))) (locus_old (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.092ms, total 3.595s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.064ms, total 3.595s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.096ms, total 3.595s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.934ms, total 3.596s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.047ms, total 3.596s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.433ms, total 3.597s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 2.145ms, total 3.597s, tagged coverage 77.7 2022-04-01 03:25:20 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 10: (Coalesce (InsertFields (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (a_index (I32 1)) (alleles_old (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1))) (locus_old (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 3.002ms, total 3.597s, tagged coverage 55.5 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.010ms, total 3.597s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 3.225ms, total 3.597s, tagged coverage 52.2 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.025ms, total 3.598s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 1.924ms, total 3.600s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.025ms, total 3.600s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 2.205ms, total 3.600s, tagged coverage 89.6 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.007ms, total 3.600s 2022-04-01 03:25:20 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 10: (Coalesce (InsertFields (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (a_index (I32 1)) (alleles_old (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1))) (locus_old (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.082ms, total 3.600s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.060ms, total 3.601s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.076ms, total 3.601s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.919ms, total 3.602s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.049ms, total 3.602s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.425ms, total 3.602s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 2.012ms, total 3.602s, tagged coverage 80.1 2022-04-01 03:25:20 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 10: (Coalesce (InsertFields (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (a_index (I32 1)) (alleles_old (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1))) (locus_old (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 2.779ms, total 3.603s, tagged coverage 58.0 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.009ms, total 3.603s 2022-04-01 03:25:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 2.985ms, total 3.603s, tagged coverage 54.5 2022-04-01 03:25:20 root: INFO: encoder cache hit 2022-04-01 03:25:20 MemoryStore: INFO: Block broadcast_8 stored as values in memory (estimated size 104.0 B, free 5.6 GB) 2022-04-01 03:25:20 MemoryStore: INFO: Block broadcast_8_piece0 stored as bytes in memory (estimated size 109.0 B, free 5.6 GB) 2022-04-01 03:25:20 BlockManagerInfo: INFO: Added broadcast_8_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 109.0 B, free: 5.6 GB) 2022-04-01 03:25:20 SparkContext: INFO: Created broadcast 8 from broadcast at SparkBackend.scala:233 2022-04-01 03:25:21 root: INFO: instruction count: 6: __C204Compiled. 2022-04-01 03:25:21 root: INFO: instruction count: 230: __C204Compiled.apply 2022-04-01 03:25:21 root: INFO: instruction count: 11: __C204Compiled.__m208addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C204Compiled.__m209addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C204Compiled.__m210addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C204Compiled.__m211addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 11: __C204Compiled.__m212addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C204Compiled.__m213addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 14: __C204Compiled.setPartitionIndex 2022-04-01 03:25:21 root: INFO: instruction count: 7: __C204Compiled.addPartitionRegion 2022-04-01 03:25:21 root: INFO: instruction count: 25: __C204Compiled.__m217DECODE_r_struct_of_r_binaryEND_TO_r_tuple_of_r_stringEND 2022-04-01 03:25:21 root: INFO: instruction count: 11: __C204Compiled.__m218read_fields_group_0 2022-04-01 03:25:21 root: INFO: instruction count: 34: __C204Compiled.__m219INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:21 root: INFO: instruction count: 41: __C204Compiled.addLiterals 2022-04-01 03:25:21 root: INFO: keysIfOneToOne struct{locus: locus, alleles: array} RVDPartitioner(struct{locus: locus, alleles: array}, [[[chr1:9710632]-[chr1:64845433]], [[chr1:64845434]-[chr2:32240318]], [[chr2:32240401]-[chr4:56493864]], [[chr4:56493939]-[chr5:68239961]], [[chr5:68239982]-[chr7:2926700]], [[chr7:2926811]-[chr10:89003044]], [[chr10:89003139]-[chr15:77035630]], [[chr15:77035767]-[chr16:81939869]], [[chr16:81956900]-[chr17:80184162]], [[chr17:80184196]-[chr19:53804068]], [[chr19:53805300]-[chrX:47206504]], [[chrX:47209889]-[chrX:154776873]]]) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.031ms, total 3.648s 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 19: (Coalesce (InsertFields (Let __iruid_4283 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)) (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1))) (InsertFields (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)) None (locus (GetField locus (Ref __iruid_4283))) (alleles (GetField alleles (Ref __iruid_4283))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.306ms, total 3.649s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.107ms, total 3.649s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.154ms, total 3.650s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.579ms, total 3.650s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.082ms, total 3.650s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.157ms, total 3.652s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.151ms, total 3.652s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.096ms, total 3.652s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.132ms, total 3.652s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.539ms, total 3.653s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.066ms, total 3.653s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.882ms, total 3.654s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.115ms, total 3.654s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.075ms, total 3.654s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.131ms, total 3.654s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.539ms, total 3.655s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.061ms, total 3.655s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.805ms, total 3.656s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 7.106ms, total 3.656s, tagged coverage 84.1 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 19: (Coalesce (InsertFields (Let __iruid_4727 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)) (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1))) (InsertFields (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)) None (locus (GetField locus (Ref __iruid_4727))) (alleles (GetField alleles (Ref __iruid_4727))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 8.349ms, total 3.657s, tagged coverage 71.6 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.016ms, total 3.657s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 8.778ms, total 3.657s, tagged coverage 68.6 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.037ms, total 3.657s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.057ms, total 3.657s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.036ms, total 3.657s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.286ms, total 3.657s, tagged coverage 45.5 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.011ms, total 3.657s 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 19: (Coalesce (InsertFields (Let __iruid_4727 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)) (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1))) (InsertFields (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)) None (locus (GetField locus (Ref __iruid_4727))) (alleles (GetField alleles (Ref __iruid_4727))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.120ms, total 3.658s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.110ms, total 3.658s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.127ms, total 3.658s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.519ms, total 3.659s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.072ms, total 3.659s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.849ms, total 3.660s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.170ms, total 3.660s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.089ms, total 3.660s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.119ms, total 3.661s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.529ms, total 3.661s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.070ms, total 3.661s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.912ms, total 3.662s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.117ms, total 3.663s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.090ms, total 3.663s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.121ms, total 3.663s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.516ms, total 3.663s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.160ms, total 3.664s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.807ms, total 3.665s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 6.569ms, total 3.665s, tagged coverage 83.7 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 19: (Coalesce (InsertFields (Let __iruid_4730 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)) (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1))) (InsertFields (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)) None (locus (GetField locus (Ref __iruid_4730))) (alleles (GetField alleles (Ref __iruid_4730))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 7.662ms, total 3.665s, tagged coverage 71.8 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.014ms, total 3.665s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 7.841ms, total 3.665s, tagged coverage 70.4 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.037ms, total 3.666s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 3.287ms, total 3.669s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.099ms, total 3.669s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 3.617ms, total 3.669s, tagged coverage 94.6 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.011ms, total 3.669s 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 19: (Coalesce (InsertFields (Let __iruid_4730 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)) (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1))) (InsertFields (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)) None (locus (GetField locus (Ref __iruid_4730))) (alleles (GetField alleles (Ref __iruid_4730))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.091ms, total 3.670s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.109ms, total 3.670s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.124ms, total 3.670s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.564ms, total 3.671s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.071ms, total 3.671s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.924ms, total 3.672s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.121ms, total 3.672s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.091ms, total 3.672s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.125ms, total 3.673s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.559ms, total 3.673s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.071ms, total 3.673s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.828ms, total 3.674s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.120ms, total 3.674s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.089ms, total 3.675s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.141ms, total 3.675s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.501ms, total 3.675s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.100ms, total 3.675s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.799ms, total 3.676s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 6.469ms, total 3.676s, tagged coverage 83.9 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 19: (Coalesce (InsertFields (Let __iruid_4733 (Apply min_rep () Struct{locus:Locus(GRCh38),alleles:Array[String]} (GetField locus (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)) (GetField alleles (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1))) (InsertFields (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)) None (locus (GetField locus (Ref __iruid_4733))) (alleles (GetField alleles (Ref __iruid_4733))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}]} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 7.557ms, total 3.677s, tagged coverage 71.8 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.016ms, total 3.677s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 7.757ms, total 3.677s, tagged coverage 70.3 2022-04-01 03:25:21 root: INFO: encoder cache hit 2022-04-01 03:25:21 MemoryStore: INFO: Block broadcast_9 stored as values in memory (estimated size 104.0 B, free 5.6 GB) 2022-04-01 03:25:21 MemoryStore: INFO: Block broadcast_9_piece0 stored as bytes in memory (estimated size 109.0 B, free 5.6 GB) 2022-04-01 03:25:21 BlockManagerInfo: INFO: Added broadcast_9_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 109.0 B, free: 5.6 GB) 2022-04-01 03:25:21 SparkContext: INFO: Created broadcast 9 from broadcast at SparkBackend.scala:233 2022-04-01 03:25:21 root: INFO: instruction count: 6: __C221Compiled. 2022-04-01 03:25:21 root: INFO: instruction count: 364: __C221Compiled.apply 2022-04-01 03:25:21 root: INFO: instruction count: 276: __C221Compiled.__m224min_rep 2022-04-01 03:25:21 root: INFO: instruction count: 15: __C221Compiled.__m227setup_null 2022-04-01 03:25:21 root: INFO: instruction count: 11: __C221Compiled.__m242addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C221Compiled.__m243addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C221Compiled.__m244addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C221Compiled.__m245addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 11: __C221Compiled.__m246addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C221Compiled.__m253addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 14: __C221Compiled.setPartitionIndex 2022-04-01 03:25:21 root: INFO: instruction count: 7: __C221Compiled.addPartitionRegion 2022-04-01 03:25:21 root: INFO: instruction count: 25: __C221Compiled.__m257DECODE_r_struct_of_r_binaryEND_TO_r_tuple_of_r_stringEND 2022-04-01 03:25:21 root: INFO: instruction count: 11: __C221Compiled.__m258read_fields_group_0 2022-04-01 03:25:21 root: INFO: instruction count: 34: __C221Compiled.__m259INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:21 root: INFO: instruction count: 41: __C221Compiled.addLiterals 2022-04-01 03:25:21 root: INFO: instruction count: 331: __C221Compiled.applyregion0_7 2022-04-01 03:25:21 root: INFO: instruction count: 6: __C261applySpills. 2022-04-01 03:25:21 SparkContext: INFO: Starting job: runJob at ContextRDD.scala:228 2022-04-01 03:25:21 DAGScheduler: INFO: Got job 3 (runJob at ContextRDD.scala:228) with 12 output partitions 2022-04-01 03:25:21 DAGScheduler: INFO: Final stage: ResultStage 3 (runJob at ContextRDD.scala:228) 2022-04-01 03:25:21 DAGScheduler: INFO: Parents of final stage: List() 2022-04-01 03:25:21 DAGScheduler: INFO: Missing parents: List() 2022-04-01 03:25:21 DAGScheduler: INFO: Submitting ResultStage 3 (MapPartitionsRDD[35] at mapPartitions at ContextRDD.scala:212), which has no missing parents 2022-04-01 03:25:21 MemoryStore: INFO: Block broadcast_10 stored as values in memory (estimated size 172.5 KB, free 5.6 GB) 2022-04-01 03:25:21 MemoryStore: INFO: Block broadcast_10_piece0 stored as bytes in memory (estimated size 60.8 KB, free 5.6 GB) 2022-04-01 03:25:21 BlockManagerInfo: INFO: Added broadcast_10_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 60.8 KB, free: 5.6 GB) 2022-04-01 03:25:21 SparkContext: INFO: Created broadcast 10 from broadcast at DAGScheduler.scala:1280 2022-04-01 03:25:21 DAGScheduler: INFO: Submitting 12 missing tasks from ResultStage 3 (MapPartitionsRDD[35] at mapPartitions at ContextRDD.scala:212) (first 15 tasks are for partitions Vector(0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11)) 2022-04-01 03:25:21 YarnScheduler: INFO: Adding task set 3.0 with 12 tasks 2022-04-01 03:25:21 TaskSetManager: INFO: Starting task 0.0 in stage 3.0 (TID 1012, ip-172-23-75-58.ec2.internal, executor 1, partition 0, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:21 TaskSetManager: INFO: Starting task 1.0 in stage 3.0 (TID 1013, ip-172-23-70-80.ec2.internal, executor 2, partition 1, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:21 TaskSetManager: INFO: Starting task 2.0 in stage 3.0 (TID 1014, ip-172-23-75-58.ec2.internal, executor 1, partition 2, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:21 TaskSetManager: INFO: Starting task 3.0 in stage 3.0 (TID 1015, ip-172-23-70-80.ec2.internal, executor 2, partition 3, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:21 TaskSetManager: INFO: Starting task 4.0 in stage 3.0 (TID 1016, ip-172-23-75-58.ec2.internal, executor 1, partition 4, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:21 TaskSetManager: INFO: Starting task 5.0 in stage 3.0 (TID 1017, ip-172-23-70-80.ec2.internal, executor 2, partition 5, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:21 TaskSetManager: INFO: Starting task 6.0 in stage 3.0 (TID 1018, ip-172-23-75-58.ec2.internal, executor 1, partition 6, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:21 TaskSetManager: INFO: Starting task 7.0 in stage 3.0 (TID 1019, ip-172-23-70-80.ec2.internal, executor 2, partition 7, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:21 TaskSetManager: INFO: Starting task 8.0 in stage 3.0 (TID 1020, ip-172-23-75-58.ec2.internal, executor 1, partition 8, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:21 TaskSetManager: INFO: Starting task 9.0 in stage 3.0 (TID 1021, ip-172-23-70-80.ec2.internal, executor 2, partition 9, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:21 TaskSetManager: INFO: Starting task 10.0 in stage 3.0 (TID 1022, ip-172-23-75-58.ec2.internal, executor 1, partition 10, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:21 TaskSetManager: INFO: Starting task 11.0 in stage 3.0 (TID 1023, ip-172-23-70-80.ec2.internal, executor 2, partition 11, PROCESS_LOCAL, 8265 bytes) 2022-04-01 03:25:21 BlockManagerInfo: INFO: Added broadcast_10_piece0 in memory on ip-172-23-70-80.ec2.internal:37501 (size: 60.8 KB, free: 181.7 GB) 2022-04-01 03:25:21 BlockManagerInfo: INFO: Added broadcast_10_piece0 in memory on ip-172-23-75-58.ec2.internal:40133 (size: 60.8 KB, free: 181.7 GB) 2022-04-01 03:25:21 BlockManagerInfo: INFO: Added broadcast_9_piece0 in memory on ip-172-23-70-80.ec2.internal:37501 (size: 109.0 B, free: 181.7 GB) 2022-04-01 03:25:21 BlockManagerInfo: INFO: Added broadcast_8_piece0 in memory on ip-172-23-70-80.ec2.internal:37501 (size: 109.0 B, free: 181.7 GB) 2022-04-01 03:25:21 BlockManagerInfo: INFO: Added broadcast_9_piece0 in memory on ip-172-23-75-58.ec2.internal:40133 (size: 109.0 B, free: 181.7 GB) 2022-04-01 03:25:21 BlockManagerInfo: INFO: Added broadcast_8_piece0 in memory on ip-172-23-75-58.ec2.internal:40133 (size: 109.0 B, free: 181.7 GB) 2022-04-01 03:25:21 TaskSetManager: INFO: Finished task 11.0 in stage 3.0 (TID 1023) in 77 ms on ip-172-23-70-80.ec2.internal (executor 2) (1/12) 2022-04-01 03:25:21 TaskSetManager: INFO: Finished task 7.0 in stage 3.0 (TID 1019) in 110 ms on ip-172-23-70-80.ec2.internal (executor 2) (2/12) 2022-04-01 03:25:21 TaskSetManager: INFO: Finished task 1.0 in stage 3.0 (TID 1013) in 112 ms on ip-172-23-70-80.ec2.internal (executor 2) (3/12) 2022-04-01 03:25:21 TaskSetManager: INFO: Finished task 5.0 in stage 3.0 (TID 1017) in 112 ms on ip-172-23-70-80.ec2.internal (executor 2) (4/12) 2022-04-01 03:25:21 TaskSetManager: INFO: Finished task 9.0 in stage 3.0 (TID 1021) in 117 ms on ip-172-23-70-80.ec2.internal (executor 2) (5/12) 2022-04-01 03:25:21 TaskSetManager: INFO: Finished task 3.0 in stage 3.0 (TID 1015) in 136 ms on ip-172-23-70-80.ec2.internal (executor 2) (6/12) 2022-04-01 03:25:21 TaskSetManager: INFO: Finished task 4.0 in stage 3.0 (TID 1016) in 154 ms on ip-172-23-75-58.ec2.internal (executor 1) (7/12) 2022-04-01 03:25:21 TaskSetManager: INFO: Finished task 8.0 in stage 3.0 (TID 1020) in 155 ms on ip-172-23-75-58.ec2.internal (executor 1) (8/12) 2022-04-01 03:25:21 TaskSetManager: INFO: Finished task 6.0 in stage 3.0 (TID 1018) in 155 ms on ip-172-23-75-58.ec2.internal (executor 1) (9/12) 2022-04-01 03:25:21 TaskSetManager: INFO: Finished task 0.0 in stage 3.0 (TID 1012) in 156 ms on ip-172-23-75-58.ec2.internal (executor 1) (10/12) 2022-04-01 03:25:21 TaskSetManager: INFO: Finished task 10.0 in stage 3.0 (TID 1022) in 155 ms on ip-172-23-75-58.ec2.internal (executor 1) (11/12) 2022-04-01 03:25:21 TaskSetManager: INFO: Finished task 2.0 in stage 3.0 (TID 1014) in 159 ms on ip-172-23-75-58.ec2.internal (executor 1) (12/12) 2022-04-01 03:25:21 YarnScheduler: INFO: Removed TaskSet 3.0, whose tasks have all completed, from pool 2022-04-01 03:25:21 DAGScheduler: INFO: ResultStage 3 (runJob at ContextRDD.scala:228) finished in 0.170 s 2022-04-01 03:25:21 DAGScheduler: INFO: Job 3 finished: runJob at ContextRDD.scala:228, took 0.172276 s 2022-04-01 03:25:21 Hail: INFO: Ordering unsorted dataset with network shuffle 2022-04-01 03:25:21 root: INFO: Unsorted keys: CURRENT={ locus: { contig: chr1, position: 9710632 }, alleles: [2; C, CAG] }, PREV={ locus: { contig: chr1, position: 9710632 }, alleles: [2; CAG, C] } 2022-04-01 03:25:21 MemoryStore: INFO: Block broadcast_11 stored as values in memory (estimated size 1721.5 KB, free 5.6 GB) 2022-04-01 03:25:21 MemoryStore: INFO: Block broadcast_11_piece0 stored as bytes in memory (estimated size 35.6 KB, free 5.6 GB) 2022-04-01 03:25:21 BlockManagerInfo: INFO: Added broadcast_11_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 35.6 KB, free: 5.6 GB) 2022-04-01 03:25:21 SparkContext: INFO: Created broadcast 11 from broadcast at RVDPartitioner.scala:93 2022-04-01 03:25:21 root: INFO: encoder cache miss (2 hits, 6 misses, 0.250) 2022-04-01 03:25:21 root: INFO: instruction count: 6: __C267etypeEncode. 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C267etypeEncode.apply 2022-04-01 03:25:21 root: INFO: instruction count: 118: __C267etypeEncode.__m268ENCODE_r_tuple_of_r_locusANDr_array_of_r_stringANDo_stringANDo_set_of_r_stringANDr_tuple_of_o_array_of_o_int32ANDo_array_of_o_float64ANDo_int32ENDANDr_int32ANDr_array_of_r_stringANDr_locusANDr_array_of_r_tuple_of_o_array_of_o_int32ANDo_int32ANDo_int32ANDo_callANDo_int32ANDo_callANDo_stringANDo_array_of_o_int32ANDo_int32ANDo_int32ANDo_array_of_o_int32ENDEND_TO_r_struct_of_r_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryANDo_binaryANDo_array_of_r_binaryANDr_struct_of_o_array_of_o_int32ANDo_array_of_o_float64ANDo_int32ENDANDr_int32ANDr_array_of_r_binaryANDr_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_struct_of_o_array_of_o_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_int32ANDo_int32ANDo_int32ANDo_array_of_o_int32ENDEND 2022-04-01 03:25:21 root: INFO: instruction count: 26: __C267etypeEncode.__m269ENCODE_r_tuple_of_r_binaryANDr_int32END_TO_r_struct_of_r_binaryANDr_int32END 2022-04-01 03:25:21 root: INFO: instruction count: 19: __C267etypeEncode.__m270ENCODE_r_binary_TO_r_binary 2022-04-01 03:25:21 root: INFO: instruction count: 7: __C267etypeEncode.__m271ENCODE_r_int32_TO_r_int32 2022-04-01 03:25:21 root: INFO: instruction count: 57: __C267etypeEncode.__m272ENCODE_r_array_of_r_binary_TO_r_array_of_r_binary 2022-04-01 03:25:21 root: INFO: instruction count: 19: __C267etypeEncode.__m273ENCODE_o_binary_TO_o_binary 2022-04-01 03:25:21 root: INFO: instruction count: 57: __C267etypeEncode.__m274ENCODE_o_array_of_r_binary_TO_o_array_of_r_binary 2022-04-01 03:25:21 root: INFO: instruction count: 81: __C267etypeEncode.__m275ENCODE_r_tuple_of_o_array_of_o_int32ANDo_array_of_o_float64ANDo_int32END_TO_r_struct_of_o_array_of_o_int32ANDo_array_of_o_float64ANDo_int32END 2022-04-01 03:25:21 root: INFO: instruction count: 126: __C267etypeEncode.__m276ENCODE_o_array_of_o_int32_TO_o_array_of_o_int32 2022-04-01 03:25:21 root: INFO: instruction count: 7: __C267etypeEncode.__m277ENCODE_o_int32_TO_o_int32 2022-04-01 03:25:21 root: INFO: instruction count: 126: __C267etypeEncode.__m278ENCODE_o_array_of_o_float64_TO_o_array_of_o_float64 2022-04-01 03:25:21 root: INFO: instruction count: 7: __C267etypeEncode.__m279ENCODE_o_float64_TO_o_float64 2022-04-01 03:25:21 root: INFO: instruction count: 53: __C267etypeEncode.__m280ENCODE_r_array_of_r_tuple_of_o_array_of_o_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_int32ANDo_int32ANDo_int32ANDo_array_of_o_int32END_TO_r_array_of_r_struct_of_o_array_of_o_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_int32ANDo_int32ANDo_int32ANDo_array_of_o_int32END 2022-04-01 03:25:21 root: INFO: instruction count: 253: __C267etypeEncode.__m281ENCODE_r_tuple_of_o_array_of_o_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_int32ANDo_int32ANDo_int32ANDo_array_of_o_int32END_TO_r_struct_of_o_array_of_o_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_int32ANDo_int32ANDo_int32ANDo_array_of_o_int32END 2022-04-01 03:25:21 root: INFO: decoder cache miss (0 hits, 3 misses, 0.000 2022-04-01 03:25:21 root: INFO: instruction count: 6: __C282etypeDecode. 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C282etypeDecode.apply 2022-04-01 03:25:21 root: INFO: instruction count: 38: __C282etypeDecode.__m283DECODE_r_struct_of_r_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryANDo_binaryANDo_array_of_r_binaryANDr_struct_of_o_array_of_o_int32ANDo_array_of_o_float64ANDo_int32ENDANDr_int32ANDr_array_of_r_binaryANDr_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_struct_of_o_array_of_o_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_int32ANDo_int32ANDo_int32ANDo_array_of_o_int32ENDEND_TO_r_tuple_of_r_locusANDr_array_of_r_stringANDo_stringANDo_set_of_r_stringANDr_tuple_of_o_array_of_o_int32ANDo_array_of_o_float64ANDo_int32ENDANDr_int32ANDr_array_of_r_stringANDr_locusANDr_array_of_r_tuple_of_o_array_of_o_int32ANDo_int32ANDo_int32ANDo_callANDo_int32ANDo_callANDo_stringANDo_array_of_o_int32ANDo_int32ANDo_int32ANDo_array_of_o_int32ENDEND 2022-04-01 03:25:21 root: INFO: instruction count: 109: __C282etypeDecode.__m284read_fields_group_0 2022-04-01 03:25:21 root: INFO: instruction count: 17: __C282etypeDecode.__m285INPLACE_DECODE_r_struct_of_r_binaryANDr_int32END_TO_r_tuple_of_r_binaryANDr_int32END 2022-04-01 03:25:21 root: INFO: instruction count: 18: __C282etypeDecode.__m286read_fields_group_0 2022-04-01 03:25:21 root: INFO: instruction count: 34: __C282etypeDecode.__m287INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:21 root: INFO: instruction count: 11: __C282etypeDecode.__m288INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:25:21 root: INFO: instruction count: 58: __C282etypeDecode.__m289INPLACE_DECODE_r_array_of_r_binary_TO_r_array_of_r_binary 2022-04-01 03:25:21 root: INFO: instruction count: 34: __C282etypeDecode.__m290INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:25:21 root: INFO: instruction count: 58: __C282etypeDecode.__m291INPLACE_DECODE_o_array_of_r_binary_TO_o_array_of_r_binary 2022-04-01 03:25:21 root: INFO: instruction count: 30: __C282etypeDecode.__m292INPLACE_DECODE_r_struct_of_o_array_of_o_int32ANDo_array_of_o_float64ANDo_int32END_TO_r_tuple_of_o_array_of_o_int32ANDo_array_of_o_float64ANDo_int32END 2022-04-01 03:25:21 root: INFO: instruction count: 88: __C282etypeDecode.__m293read_fields_group_0 2022-04-01 03:25:21 root: INFO: instruction count: 105: __C282etypeDecode.__m294INPLACE_DECODE_o_array_of_o_int32_TO_o_array_of_o_int32 2022-04-01 03:25:21 root: INFO: instruction count: 11: __C282etypeDecode.__m295INPLACE_DECODE_o_int32_TO_o_int32 2022-04-01 03:25:21 root: INFO: instruction count: 105: __C282etypeDecode.__m296INPLACE_DECODE_o_array_of_o_float64_TO_o_array_of_o_float64 2022-04-01 03:25:21 root: INFO: instruction count: 11: __C282etypeDecode.__m297INPLACE_DECODE_o_float64_TO_o_float64 2022-04-01 03:25:21 root: INFO: instruction count: 58: __C282etypeDecode.__m298INPLACE_DECODE_r_array_of_r_struct_of_o_array_of_o_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_int32ANDo_int32ANDo_int32ANDo_array_of_o_int32END_TO_r_array_of_r_tuple_of_o_array_of_o_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_int32ANDo_int32ANDo_int32ANDo_array_of_o_int32END 2022-04-01 03:25:21 root: INFO: instruction count: 39: __C282etypeDecode.__m299INPLACE_DECODE_r_struct_of_o_array_of_o_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_int32ANDo_int32ANDo_int32ANDo_array_of_o_int32END_TO_r_tuple_of_o_array_of_o_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_int32ANDo_int32ANDo_int32ANDo_array_of_o_int32END 2022-04-01 03:25:21 root: INFO: instruction count: 312: __C282etypeDecode.__m300read_fields_group_0 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.028ms, total 4.006s 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 6: (Coalesce (InsertFields (In +PCStruct{__cols:+PCArray[+PCStruct{s:+PCString}]} 0) ("gencodeVersion" "__cols") (gencodeVersion (Str "25"))) (Die Struct{gencodeVersion:String,__cols:Array[Struct{s:String}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.174ms, total 4.007s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.059ms, total 4.007s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.063ms, total 4.007s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.282ms, total 4.007s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.035ms, total 4.007s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.300ms, total 4.008s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 1.245ms, total 4.008s, tagged coverage 73.3 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 6: (Coalesce (InsertFields (In +PCStruct{__cols:+PCArray[+PCStruct{s:+PCString}]} 0) ("gencodeVersion" "__cols") (gencodeVersion (Str "25"))) (Die Struct{gencodeVersion:String,__cols:Array[Struct{s:String}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 1.617ms, total 4.008s, tagged coverage 56.5 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.007ms, total 4.008s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 1.849ms, total 4.008s, tagged coverage 51.3 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.015ms, total 4.008s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.025ms, total 4.008s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.016ms, total 4.008s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.150ms, total 4.008s, tagged coverage 38.2 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.004ms, total 4.008s 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 6: (Coalesce (InsertFields (In +PCStruct{__cols:+PCArray[+PCStruct{s:+PCString}]} 0) ("gencodeVersion" "__cols") (gencodeVersion (Str "25"))) (Die Struct{gencodeVersion:String,__cols:Array[Struct{s:String}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.058ms, total 4.009s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.033ms, total 4.009s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.050ms, total 4.009s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.209ms, total 4.009s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.030ms, total 4.009s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.224ms, total 4.009s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 0.849ms, total 4.009s, tagged coverage 70.9 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 6: (Coalesce (InsertFields (In +PCStruct{__cols:+PCArray[+PCStruct{s:+PCString}]} 0) ("gencodeVersion" "__cols") (gencodeVersion (Str "25"))) (Die Struct{gencodeVersion:String,__cols:Array[Struct{s:String}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 1.102ms, total 4.010s, tagged coverage 54.7 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.008ms, total 4.010s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 1.213ms, total 4.010s, tagged coverage 50.6 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.015ms, total 4.010s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 0.416ms, total 4.010s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.017ms, total 4.010s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 0.595ms, total 4.010s, tagged coverage 75.3 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.004ms, total 4.011s 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 6: (Coalesce (InsertFields (In +PCStruct{__cols:+PCArray[+PCStruct{s:+PCString}]} 0) ("gencodeVersion" "__cols") (gencodeVersion (Str "25"))) (Die Struct{gencodeVersion:String,__cols:Array[Struct{s:String}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.053ms, total 4.011s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.034ms, total 4.011s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.048ms, total 4.011s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.205ms, total 4.011s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.027ms, total 4.011s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.219ms, total 4.011s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 0.831ms, total 4.011s, tagged coverage 70.5 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 6: (Coalesce (InsertFields (In +PCStruct{__cols:+PCArray[+PCStruct{s:+PCString}]} 0) ("gencodeVersion" "__cols") (gencodeVersion (Str "25"))) (Die Struct{gencodeVersion:String,__cols:Array[Struct{s:String}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 1.204ms, total 4.012s, tagged coverage 48.7 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.006ms, total 4.012s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 1.329ms, total 4.012s, tagged coverage 44.9 2022-04-01 03:25:21 root: INFO: encoder cache hit 2022-04-01 03:25:21 MemoryStore: INFO: Block broadcast_12 stored as values in memory (estimated size 112.0 B, free 5.6 GB) 2022-04-01 03:25:21 MemoryStore: INFO: Block broadcast_12_piece0 stored as bytes in memory (estimated size 111.0 B, free 5.6 GB) 2022-04-01 03:25:21 BlockManagerInfo: INFO: Added broadcast_12_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 111.0 B, free: 5.6 GB) 2022-04-01 03:25:21 SparkContext: INFO: Created broadcast 12 from broadcast at SparkBackend.scala:233 2022-04-01 03:25:21 root: INFO: instruction count: 6: __C301Compiled. 2022-04-01 03:25:21 root: INFO: instruction count: 65: __C301Compiled.apply 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C301Compiled.__m306addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C301Compiled.__m307addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 14: __C301Compiled.setPartitionIndex 2022-04-01 03:25:21 root: INFO: instruction count: 7: __C301Compiled.addPartitionRegion 2022-04-01 03:25:21 root: INFO: instruction count: 25: __C301Compiled.__m311DECODE_r_struct_of_r_binaryANDr_binaryEND_TO_r_tuple_of_r_stringANDr_stringEND 2022-04-01 03:25:21 root: INFO: instruction count: 18: __C301Compiled.__m312read_fields_group_0 2022-04-01 03:25:21 root: INFO: instruction count: 34: __C301Compiled.__m313INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:21 root: INFO: instruction count: 50: __C301Compiled.addLiterals 2022-04-01 03:25:21 root: INFO: decoder cache miss (0 hits, 4 misses, 0.000 2022-04-01 03:25:21 root: INFO: instruction count: 6: __C315etypeDecode. 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C315etypeDecode.apply 2022-04-01 03:25:21 root: INFO: instruction count: 19: __C315etypeDecode.__m316DECODE_r_struct_of_END_TO_r_tuple_of_END 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.042ms, total 4.126s 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 42: (Coalesce (InsertFields (Let __iruid_4284 (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)) (InsertFields (Ref __iruid_4284) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN") (vep (GetField vep (GetField __uid_4 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)))) (aIndex (GetField a_index (Ref __iruid_4284))) (AC (ApplyIR indexArray () Int32 (GetField AC (GetField info (Ref __iruid_4284))) (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_4284)) (I32 1)) (Str " File \"/h..."))) (AF (ApplyIR indexArray () Float64 (GetField AF (GetField info (Ref __iruid_4284))) (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_4284)) (I32 1)) (Str " File \"/h..."))) (alt (ApplyIR indexArray () String (GetField alleles (Ref __iruid_4284)) (I32 1) (Str " File \"/h..."))) (AN (GetField AN (GetField info (Ref __iruid_4284)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.414ms, total 4.128s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.161ms, total 4.129s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.469ms, total 4.129s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.872ms, total 4.130s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.122ms, total 4.130s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.886ms, total 4.132s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.208ms, total 4.133s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.140ms, total 4.133s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.415ms, total 4.133s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.803ms, total 4.134s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.108ms, total 4.134s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.672ms, total 4.136s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.180ms, total 4.136s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.136ms, total 4.136s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.386ms, total 4.137s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 1.560ms, total 4.138s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.103ms, total 4.139s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.580ms, total 4.140s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 12.273ms, total 4.140s, tagged coverage 91.4 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 42: (Coalesce (InsertFields (Let __iruid_4818 (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)) (InsertFields (Ref __iruid_4818) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN") (vep (GetField vep (GetField __uid_4 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)))) (aIndex (GetField a_index (Ref __iruid_4818))) (AC (ApplyIR indexArray () Int32 (GetField AC (GetField info (Ref __iruid_4818))) (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_4818)) (I32 1)) (Str " File \"/h..."))) (AF (ApplyIR indexArray () Float64 (GetField AF (GetField info (Ref __iruid_4818))) (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_4818)) (I32 1)) (Str " File \"/h..."))) (alt (ApplyIR indexArray () String (GetField alleles (Ref __iruid_4818)) (I32 1) (Str " File \"/h..."))) (AN (GetField AN (GetField info (Ref __iruid_4818)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 15.546ms, total 4.142s, tagged coverage 72.2 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.020ms, total 4.142s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 15.862ms, total 4.142s, tagged coverage 71.1 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.058ms, total 4.142s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.265ms, total 4.142s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.137ms, total 4.143s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.569ms, total 4.143s, tagged coverage 80.7 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.032ms, total 4.143s 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 84: (Coalesce (InsertFields (Let __iruid_4818 (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)) (InsertFields (Ref __iruid_4818) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN") (vep (GetField vep (GetField __uid_4 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)))) (aIndex (GetField a_index (Ref __iruid_4818))) (AC (Let __iruid_4828 (GetField AC (GetField info (Ref __iruid_4818))) (Let __iruid_4829 (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_4818)) (I32 1)) (Let __iruid_4830 (Str " File \"/h...") (ArrayRef (Ref __iruid_4828) (If (ApplyComparisonOp LT (Ref __iruid_4829) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_4828)) (Ref __iruid_4829)) (Ref __iruid_4829)) (Ref __iruid_4830)))))) (AF (Let __iruid_4831 (GetField AF (GetField info (Ref __iruid_4818))) (Let __iruid_4832 (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_4818)) (I32 1)) (Let __iruid_4833 (Str " File \"/h...") (ArrayRef (Ref __iruid_4831) (If (ApplyComparisonOp LT (Ref __iruid_4832) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_4831)) (Ref __iruid_4832)) (Ref __iruid_4832)) (Ref __iruid_4833)))))) (alt (Let __iruid_4834 (GetField alleles (Ref __iruid_4818)) (Let __iruid_4835 (I32 1) (Let __iruid_4836 (Str " File \"/h...") (ArrayRef (Ref __iruid_4834) (If (ApplyComparisonOp LT (Ref __iruid_4835) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_4834)) (Ref __iruid_4835)) (Ref __iruid_4835)) (Ref __iruid_4836)))))) (AN (GetField AN (GetField info (Ref __iruid_4818)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.247ms, total 4.145s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.215ms, total 4.145s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.390ms, total 4.146s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 1.490ms, total 4.147s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.242ms, total 4.148s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.007ms, total 4.150s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 1.129ms, total 4.151s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.193ms, total 4.151s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.383ms, total 4.152s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 1.278ms, total 4.153s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.170ms, total 4.153s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.652ms, total 4.155s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.220ms, total 4.155s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.183ms, total 4.155s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.311ms, total 4.156s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 1.170ms, total 4.157s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.159ms, total 4.157s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.619ms, total 4.159s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 13.933ms, total 4.159s, tagged coverage 93.7 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 66: (Coalesce (InsertFields (Let __iruid_4853 (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)) (InsertFields (Ref __iruid_4853) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN") (vep (GetField vep (GetField __uid_4 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)))) (aIndex (GetField a_index (Ref __iruid_4853))) (AC (Let __iruid_4854 (GetField AC (GetField info (Ref __iruid_4853))) (Let __iruid_4855 (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_4853)) (I32 1)) (ArrayRef (Ref __iruid_4854) (If (ApplyComparisonOp LT (Ref __iruid_4855) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_4854)) (Ref __iruid_4855)) (Ref __iruid_4855)) (Str " File \"/h..."))))) (AF (Let __iruid_4856 (GetField AF (GetField info (Ref __iruid_4853))) (Let __iruid_4857 (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_4853)) (I32 1)) (ArrayRef (Ref __iruid_4856) (If (ApplyComparisonOp LT (Ref __iruid_4857) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_4856)) (Ref __iruid_4857)) (Ref __iruid_4857)) (Str " File \"/h..."))))) (alt (ArrayRef (GetField alleles (Ref __iruid_4853)) (I32 1) (Str " File \"/h..."))) (AN (GetField AN (GetField info (Ref __iruid_4853)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 17.068ms, total 4.160s, tagged coverage 76.5 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.029ms, total 4.161s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 17.263ms, total 4.161s, tagged coverage 76.0 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.106ms, total 4.161s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 13.249ms, total 4.174s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.113ms, total 4.175s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 13.666ms, total 4.175s, tagged coverage 98.5 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.022ms, total 4.175s 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 66: (Coalesce (InsertFields (Let __iruid_4853 (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)) (InsertFields (Ref __iruid_4853) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN") (vep (GetField vep (GetField __uid_4 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)))) (aIndex (GetField a_index (Ref __iruid_4853))) (AC (Let __iruid_4854 (GetField AC (GetField info (Ref __iruid_4853))) (Let __iruid_4855 (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_4853)) (I32 1)) (ArrayRef (Ref __iruid_4854) (If (ApplyComparisonOp LT (Ref __iruid_4855) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_4854)) (Ref __iruid_4855)) (Ref __iruid_4855)) (Str " File \"/h..."))))) (AF (Let __iruid_4856 (GetField AF (GetField info (Ref __iruid_4853))) (Let __iruid_4857 (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_4853)) (I32 1)) (ArrayRef (Ref __iruid_4856) (If (ApplyComparisonOp LT (Ref __iruid_4857) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_4856)) (Ref __iruid_4857)) (Ref __iruid_4857)) (Str " File \"/h..."))))) (alt (ArrayRef (GetField alleles (Ref __iruid_4853)) (I32 1) (Str " File \"/h..."))) (AN (GetField AN (GetField info (Ref __iruid_4853)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.224ms, total 4.177s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.203ms, total 4.177s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.331ms, total 4.178s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 1.388ms, total 4.179s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.162ms, total 4.179s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.945ms, total 4.181s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.237ms, total 4.182s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.190ms, total 4.182s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.315ms, total 4.182s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 1.132ms, total 4.183s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.146ms, total 4.184s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.695ms, total 4.185s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.236ms, total 4.186s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.197ms, total 4.186s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.323ms, total 4.186s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 1.218ms, total 4.187s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.170ms, total 4.188s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.655ms, total 4.189s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 12.656ms, total 4.189s, tagged coverage 93.0 2022-04-01 03:25:21 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 66: (Coalesce (InsertFields (Let __iruid_4868 (SelectFields (locus alleles rsid filters info a_index alleles_old locus_old) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)) (InsertFields (Ref __iruid_4868) ("locus" "alleles" "rsid" "filters" "info" "a_index" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN") (vep (GetField vep (GetField __uid_4 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)))) (aIndex (GetField a_index (Ref __iruid_4868))) (AC (Let __iruid_4869 (GetField AC (GetField info (Ref __iruid_4868))) (Let __iruid_4870 (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_4868)) (I32 1)) (ArrayRef (Ref __iruid_4869) (If (ApplyComparisonOp LT (Ref __iruid_4870) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_4869)) (Ref __iruid_4870)) (Ref __iruid_4870)) (Str " File \"/h..."))))) (AF (Let __iruid_4871 (GetField AF (GetField info (Ref __iruid_4868))) (Let __iruid_4872 (ApplyBinaryPrimOp Subtract (GetField a_index (Ref __iruid_4868)) (I32 1)) (ArrayRef (Ref __iruid_4871) (If (ApplyComparisonOp LT (Ref __iruid_4872) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_4871)) (Ref __iruid_4872)) (Ref __iruid_4872)) (Str " File \"/h..."))))) (alt (ArrayRef (GetField alleles (Ref __iruid_4868)) (I32 1) (Str " File \"/h..."))) (AN (GetField AN (GetField info (Ref __iruid_4868)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_4:PCStruct{vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],info:Struct{AC:Array[Int32],AF:Array[Float64],AN:Int32},a_index:Int32,alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 15.845ms, total 4.191s, tagged coverage 74.3 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.029ms, total 4.191s 2022-04-01 03:25:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 16.040ms, total 4.191s, tagged coverage 73.7 2022-04-01 03:25:21 root: INFO: encoder cache hit 2022-04-01 03:25:21 MemoryStore: INFO: Block broadcast_13 stored as values in memory (estimated size 104.0 B, free 5.6 GB) 2022-04-01 03:25:21 MemoryStore: INFO: Block broadcast_13_piece0 stored as bytes in memory (estimated size 109.0 B, free 5.6 GB) 2022-04-01 03:25:21 BlockManagerInfo: INFO: Added broadcast_13_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 109.0 B, free: 5.6 GB) 2022-04-01 03:25:21 SparkContext: INFO: Created broadcast 13 from broadcast at SparkBackend.scala:233 2022-04-01 03:25:21 root: INFO: instruction count: 6: __C317Compiled. 2022-04-01 03:25:21 root: INFO: instruction count: 746: __C317Compiled.apply 2022-04-01 03:25:21 root: INFO: instruction count: 11: __C317Compiled.__m323addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C317Compiled.__m324addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C317Compiled.__m325addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C317Compiled.__m326addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 11: __C317Compiled.__m327addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 11: __C317Compiled.__m331addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 26: __C317Compiled.__m338cord 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C317Compiled.__m345addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C317Compiled.__m349addIRIntermediate 2022-04-01 03:25:21 root: INFO: instruction count: 14: __C317Compiled.setPartitionIndex 2022-04-01 03:25:21 root: INFO: instruction count: 7: __C317Compiled.addPartitionRegion 2022-04-01 03:25:21 root: INFO: instruction count: 25: __C317Compiled.__m353DECODE_r_struct_of_r_binaryEND_TO_r_tuple_of_r_stringEND 2022-04-01 03:25:21 root: INFO: instruction count: 11: __C317Compiled.__m354read_fields_group_0 2022-04-01 03:25:21 root: INFO: instruction count: 34: __C317Compiled.__m355INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:21 root: INFO: instruction count: 41: __C317Compiled.addLiterals 2022-04-01 03:25:21 root: INFO: instruction count: 565: __C317Compiled.applyregion59_92 2022-04-01 03:25:21 root: INFO: instruction count: 305: __C317Compiled.applyregion0_7 2022-04-01 03:25:21 root: INFO: instruction count: 6: __C357applySpills. 2022-04-01 03:25:21 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:21 root: INFO: decoder cache miss (0 hits, 5 misses, 0.000 2022-04-01 03:25:21 root: INFO: instruction count: 6: __C367etypeDecode. 2022-04-01 03:25:21 root: INFO: instruction count: 8: __C367etypeDecode.apply 2022-04-01 03:25:21 root: INFO: instruction count: 25: __C367etypeDecode.__m368DECODE_r_struct_of_r_binaryANDr_array_of_r_struct_of_r_binaryANDr_binaryENDANDr_binaryEND_TO_r_tuple_of_END 2022-04-01 03:25:21 root: INFO: instruction count: 16: __C367etypeDecode.__m369read_fields_group_0 2022-04-01 03:25:21 root: INFO: instruction count: 10: __C367etypeDecode.__m370SKIP_r_binary 2022-04-01 03:25:21 root: INFO: instruction count: 28: __C367etypeDecode.__m371SKIP_r_array_of_r_struct_of_r_binaryANDr_binaryEND 2022-04-01 03:25:21 root: INFO: instruction count: 19: __C367etypeDecode.__m372SKIP_r_struct_of_r_binaryANDr_binaryEND 2022-04-01 03:25:21 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/parts/part-0' for reading 2022-04-01 03:25:21 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 91 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 80 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 64 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 71 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 92 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 93 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 97 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 100 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 96 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 52 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 55 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 57 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 88 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 82 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 70 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 69 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 62 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 74 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 61 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 75 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 60 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 72 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 78 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 89 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 67 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 85 2022-04-01 03:25:23 BlockManagerInfo: INFO: Removed broadcast_10_piece0 on ip-172-23-75-58.ec2.internal:40133 in memory (size: 60.8 KB, free: 181.7 GB) 2022-04-01 03:25:23 BlockManagerInfo: INFO: Removed broadcast_10_piece0 on ip-172-23-70-80.ec2.internal:37501 in memory (size: 60.8 KB, free: 181.7 GB) 2022-04-01 03:25:23 BlockManagerInfo: INFO: Removed broadcast_10_piece0 on ip-172-23-79-68.ec2.internal:36757 in memory (size: 60.8 KB, free: 5.6 GB) 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 76 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 83 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 73 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 63 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 79 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 77 2022-04-01 03:25:23 BlockManagerInfo: INFO: Removed broadcast_7_piece0 on ip-172-23-70-80.ec2.internal:37501 in memory (size: 49.5 KB, free: 181.7 GB) 2022-04-01 03:25:23 BlockManagerInfo: INFO: Removed broadcast_7_piece0 on ip-172-23-75-58.ec2.internal:40133 in memory (size: 49.5 KB, free: 181.7 GB) 2022-04-01 03:25:23 BlockManagerInfo: INFO: Removed broadcast_7_piece0 on ip-172-23-79-68.ec2.internal:36757 in memory (size: 49.5 KB, free: 5.6 GB) 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 54 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 68 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 59 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 87 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 51 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 56 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 94 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 95 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 99 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 81 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 66 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 58 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 84 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 86 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 98 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 53 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 90 2022-04-01 03:25:23 ContextCleaner: INFO: Cleaned accumulator 65 2022-04-01 03:25:23 root: INFO: decoder cache miss (0 hits, 6 misses, 0.000 2022-04-01 03:25:23 root: INFO: instruction count: 6: __C373etypeDecode. 2022-04-01 03:25:23 root: INFO: instruction count: 8: __C373etypeDecode.apply 2022-04-01 03:25:23 root: INFO: instruction count: 47: __C373etypeDecode.__m374DECODE_r_struct_of_o_struct_of_r_binaryANDr_int32ENDANDo_array_of_o_binaryANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_struct_of_o_binaryENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryENDANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_int32ENDANDo_float32ANDo_float64END_TO_r_tuple_of_o_locusANDo_array_of_o_stringANDo_tuple_of_o_float32ENDEND 2022-04-01 03:25:23 root: INFO: instruction count: 283: __C373etypeDecode.__m375read_fields_group_0 2022-04-01 03:25:23 root: INFO: instruction count: 17: __C373etypeDecode.__m376INPLACE_DECODE_o_struct_of_r_binaryANDr_int32END_TO_o_tuple_of_r_binaryANDr_int32END 2022-04-01 03:25:23 root: INFO: instruction count: 18: __C373etypeDecode.__m377read_fields_group_0 2022-04-01 03:25:23 root: INFO: instruction count: 34: __C373etypeDecode.__m378INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:23 root: INFO: instruction count: 11: __C373etypeDecode.__m379INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:25:23 root: INFO: instruction count: 105: __C373etypeDecode.__m380INPLACE_DECODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:25:23 root: INFO: instruction count: 34: __C373etypeDecode.__m381INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:25:23 root: INFO: instruction count: 84: __C373etypeDecode.__m382SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64END 2022-04-01 03:25:23 root: INFO: instruction count: 6: __C373etypeDecode.__m383SKIP_o_int32 2022-04-01 03:25:23 root: INFO: instruction count: 6: __C373etypeDecode.__m384SKIP_o_float64 2022-04-01 03:25:23 root: INFO: instruction count: 39: __C373etypeDecode.__m385SKIP_o_struct_of_o_binaryEND 2022-04-01 03:25:23 root: INFO: instruction count: 10: __C373etypeDecode.__m386SKIP_o_binary 2022-04-01 03:25:23 root: INFO: instruction count: 30: __C373etypeDecode.__m387INPLACE_DECODE_o_struct_of_o_float32END_TO_o_tuple_of_o_float32END 2022-04-01 03:25:23 root: INFO: instruction count: 32: __C373etypeDecode.__m388read_fields_group_0 2022-04-01 03:25:23 root: INFO: instruction count: 11: __C373etypeDecode.__m389INPLACE_DECODE_o_float32_TO_o_float32 2022-04-01 03:25:23 root: INFO: instruction count: 39: __C373etypeDecode.__m390SKIP_o_struct_of_o_float64END 2022-04-01 03:25:23 root: INFO: instruction count: 144: __C373etypeDecode.__m391SKIP_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:25:23 root: INFO: instruction count: 99: __C373etypeDecode.__m392SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:25:23 root: INFO: instruction count: 39: __C373etypeDecode.__m393SKIP_o_struct_of_o_float64END 2022-04-01 03:25:23 root: INFO: instruction count: 39: __C373etypeDecode.__m394SKIP_o_struct_of_o_float32END 2022-04-01 03:25:23 root: INFO: instruction count: 6: __C373etypeDecode.__m395SKIP_o_float32 2022-04-01 03:25:23 root: INFO: instruction count: 129: __C373etypeDecode.__m396SKIP_o_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:25:23 root: INFO: instruction count: 129: __C373etypeDecode.__m397SKIP_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:25:23 root: INFO: instruction count: 39: __C373etypeDecode.__m398SKIP_o_struct_of_o_int32END 2022-04-01 03:25:27 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:28 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.020ms, total 11.429s 2022-04-01 03:25:28 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_5:PCStruct{cadd:PCStruct{PHRED:PFloat32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (cadd (GetField cadd (GetField __uid_5 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_5:PCStruct{cadd:PCStruct{PHRED:PFloat32}}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.467ms, total 11.432s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.084ms, total 11.432s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.133ms, total 11.432s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.258ms, total 11.433s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.053ms, total 11.433s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.639ms, total 11.433s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 1.994ms, total 11.433s, tagged coverage 81.9 2022-04-01 03:25:28 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_5:PCStruct{cadd:PCStruct{PHRED:PFloat32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (cadd (GetField cadd (GetField __uid_5 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_5:PCStruct{cadd:PCStruct{PHRED:PFloat32}}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 4.843ms, total 11.434s, tagged coverage 33.7 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.011ms, total 11.435s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 5.133ms, total 11.435s, tagged coverage 32.4 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.039ms, total 11.435s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.033ms, total 11.435s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.019ms, total 11.435s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.208ms, total 11.435s, tagged coverage 44.1 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.006ms, total 11.435s 2022-04-01 03:25:28 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_5:PCStruct{cadd:PCStruct{PHRED:PFloat32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (cadd (GetField cadd (GetField __uid_5 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_5:PCStruct{cadd:PCStruct{PHRED:PFloat32}}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.085ms, total 11.436s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.052ms, total 11.437s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.083ms, total 11.437s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.223ms, total 11.437s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.038ms, total 11.437s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.589ms, total 11.438s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 1.364ms, total 11.438s, tagged coverage 78.4 2022-04-01 03:25:28 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_5:PCStruct{cadd:PCStruct{PHRED:PFloat32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (cadd (GetField cadd (GetField __uid_5 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_5:PCStruct{cadd:PCStruct{PHRED:PFloat32}}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 3.543ms, total 11.439s, tagged coverage 30.2 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.008ms, total 11.439s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 3.694ms, total 11.439s, tagged coverage 29.3 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.031ms, total 11.439s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 3.998ms, total 11.443s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.054ms, total 11.443s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 4.280ms, total 11.443s, tagged coverage 95.4 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.006ms, total 11.444s 2022-04-01 03:25:28 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_5:PCStruct{cadd:PCStruct{PHRED:PFloat32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (cadd (GetField cadd (GetField __uid_5 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_5:PCStruct{cadd:PCStruct{PHRED:PFloat32}}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.084ms, total 11.445s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.069ms, total 11.445s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.079ms, total 11.445s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.195ms, total 11.445s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.036ms, total 11.445s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.647ms, total 11.446s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 1.436ms, total 11.446s, tagged coverage 77.3 2022-04-01 03:25:28 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_5:PCStruct{cadd:PCStruct{PHRED:PFloat32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (cadd (GetField cadd (GetField __uid_5 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],info:+PCStruct{AC:PCArray[PInt32],AF:PCArray[PFloat64],AN:PInt32},a_index:+PInt32,alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_5:PCStruct{cadd:PCStruct{PHRED:PFloat32}}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 3.327ms, total 11.447s, tagged coverage 33.4 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.008ms, total 11.447s 2022-04-01 03:25:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 3.463ms, total 11.447s, tagged coverage 32.4 2022-04-01 03:25:28 root: INFO: encoder cache hit 2022-04-01 03:25:28 MemoryStore: INFO: Block broadcast_14 stored as values in memory (estimated size 104.0 B, free 5.6 GB) 2022-04-01 03:25:28 MemoryStore: INFO: Block broadcast_14_piece0 stored as bytes in memory (estimated size 109.0 B, free 5.6 GB) 2022-04-01 03:25:28 BlockManagerInfo: INFO: Added broadcast_14_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 109.0 B, free: 5.6 GB) 2022-04-01 03:25:28 SparkContext: INFO: Created broadcast 14 from broadcast at SparkBackend.scala:233 2022-04-01 03:25:28 root: INFO: instruction count: 6: __C399Compiled. 2022-04-01 03:25:28 root: INFO: instruction count: 478: __C399Compiled.apply 2022-04-01 03:25:28 root: INFO: instruction count: 11: __C399Compiled.__m403addIRIntermediate 2022-04-01 03:25:28 root: INFO: instruction count: 8: __C399Compiled.__m404addIRIntermediate 2022-04-01 03:25:28 root: INFO: instruction count: 8: __C399Compiled.__m405addIRIntermediate 2022-04-01 03:25:28 root: INFO: instruction count: 8: __C399Compiled.__m406addIRIntermediate 2022-04-01 03:25:28 root: INFO: instruction count: 11: __C399Compiled.__m407addIRIntermediate 2022-04-01 03:25:28 root: INFO: instruction count: 8: __C399Compiled.__m408addIRIntermediate 2022-04-01 03:25:28 root: INFO: instruction count: 8: __C399Compiled.__m409addIRIntermediate 2022-04-01 03:25:28 root: INFO: instruction count: 11: __C399Compiled.__m413addIRIntermediate 2022-04-01 03:25:28 root: INFO: instruction count: 14: __C399Compiled.setPartitionIndex 2022-04-01 03:25:28 root: INFO: instruction count: 7: __C399Compiled.addPartitionRegion 2022-04-01 03:25:28 root: INFO: instruction count: 25: __C399Compiled.__m417DECODE_r_struct_of_r_binaryEND_TO_r_tuple_of_r_stringEND 2022-04-01 03:25:28 root: INFO: instruction count: 11: __C399Compiled.__m418read_fields_group_0 2022-04-01 03:25:28 root: INFO: instruction count: 34: __C399Compiled.__m419INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:28 root: INFO: instruction count: 41: __C399Compiled.addLiterals 2022-04-01 03:25:28 root: INFO: instruction count: 212: __C399Compiled.applyregion0_7 2022-04-01 03:25:28 root: INFO: instruction count: 156: __C399Compiled.applyregion16_23 2022-04-01 03:25:28 root: INFO: instruction count: 6: __C421applySpills. 2022-04-01 03:25:28 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:29 root: INFO: decoder cache miss (0 hits, 7 misses, 0.000 2022-04-01 03:25:29 root: INFO: instruction count: 6: __C429etypeDecode. 2022-04-01 03:25:29 root: INFO: instruction count: 8: __C429etypeDecode.apply 2022-04-01 03:25:29 root: INFO: instruction count: 25: __C429etypeDecode.__m430DECODE_r_struct_of_r_binaryANDr_binaryEND_TO_r_tuple_of_END 2022-04-01 03:25:29 root: INFO: instruction count: 12: __C429etypeDecode.__m431read_fields_group_0 2022-04-01 03:25:29 root: INFO: instruction count: 10: __C429etypeDecode.__m432SKIP_r_binary 2022-04-01 03:25:29 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/parts/part-0' for reading 2022-04-01 03:25:29 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:29 root: INFO: decoder cache miss (0 hits, 8 misses, 0.000 2022-04-01 03:25:29 root: INFO: instruction count: 6: __C433etypeDecode. 2022-04-01 03:25:29 root: INFO: instruction count: 8: __C433etypeDecode.apply 2022-04-01 03:25:29 root: INFO: instruction count: 38: __C433etypeDecode.__m434DECODE_r_struct_of_r_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryANDo_binaryANDo_float64ANDo_array_of_r_binaryANDr_struct_of_o_float64ANDo_float64ANDo_float64ANDo_int32ANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_int32ENDANDo_array_of_r_binaryANDr_int32ANDr_boolANDo_int32END_TO_r_tuple_of_r_locusANDr_array_of_r_stringANDr_tuple_of_o_int32ENDEND 2022-04-01 03:25:29 root: INFO: instruction count: 108: __C433etypeDecode.__m435read_fields_group_0 2022-04-01 03:25:29 root: INFO: instruction count: 17: __C433etypeDecode.__m436INPLACE_DECODE_r_struct_of_r_binaryANDr_int32END_TO_r_tuple_of_r_binaryANDr_int32END 2022-04-01 03:25:29 root: INFO: instruction count: 18: __C433etypeDecode.__m437read_fields_group_0 2022-04-01 03:25:29 root: INFO: instruction count: 34: __C433etypeDecode.__m438INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:29 root: INFO: instruction count: 11: __C433etypeDecode.__m439INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:25:29 root: INFO: instruction count: 58: __C433etypeDecode.__m440INPLACE_DECODE_r_array_of_r_binary_TO_r_array_of_r_binary 2022-04-01 03:25:29 root: INFO: instruction count: 10: __C433etypeDecode.__m441SKIP_o_binary 2022-04-01 03:25:29 root: INFO: instruction count: 6: __C433etypeDecode.__m442SKIP_o_float64 2022-04-01 03:25:29 root: INFO: instruction count: 28: __C433etypeDecode.__m443SKIP_o_array_of_r_binary 2022-04-01 03:25:29 root: INFO: instruction count: 10: __C433etypeDecode.__m444SKIP_r_binary 2022-04-01 03:25:29 root: INFO: instruction count: 48: __C433etypeDecode.__m445INPLACE_DECODE_r_struct_of_o_float64ANDo_float64ANDo_float64ANDo_int32ANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_int32END_TO_r_tuple_of_o_int32END 2022-04-01 03:25:29 root: INFO: instruction count: 347: __C433etypeDecode.__m446read_fields_group_0 2022-04-01 03:25:29 root: INFO: instruction count: 11: __C433etypeDecode.__m447INPLACE_DECODE_o_int32_TO_o_int32 2022-04-01 03:25:29 root: INFO: instruction count: 59: __C433etypeDecode.__m448SKIP_o_array_of_o_binary 2022-04-01 03:25:29 root: INFO: instruction count: 6: __C433etypeDecode.__m449SKIP_o_int32 2022-04-01 03:25:29 root: INFO: instruction count: 6: __C433etypeDecode.__m450SKIP_r_int32 2022-04-01 03:25:29 root: INFO: instruction count: 6: __C433etypeDecode.__m451SKIP_r_bool 2022-04-01 03:25:29 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:30 root: INFO: decoder cache hit 2022-04-01 03:25:30 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/parts/part-0' for reading 2022-04-01 03:25:30 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:30 root: INFO: decoder cache miss (1 hits, 9 misses, 0.100 2022-04-01 03:25:30 root: INFO: instruction count: 6: __C452etypeDecode. 2022-04-01 03:25:30 root: INFO: instruction count: 8: __C452etypeDecode.apply 2022-04-01 03:25:30 root: INFO: instruction count: 38: __C452etypeDecode.__m453DECODE_r_struct_of_r_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryANDo_binaryANDo_float64ANDo_array_of_r_binaryANDr_struct_of_o_float64ANDo_float64ANDo_float64ANDo_int32ANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_int32ENDANDo_array_of_r_binaryANDr_int32ANDr_boolANDo_int32END_TO_r_tuple_of_r_locusANDr_array_of_r_stringANDr_tuple_of_o_array_of_o_stringENDEND 2022-04-01 03:25:30 root: INFO: instruction count: 108: __C452etypeDecode.__m454read_fields_group_0 2022-04-01 03:25:30 root: INFO: instruction count: 17: __C452etypeDecode.__m455INPLACE_DECODE_r_struct_of_r_binaryANDr_int32END_TO_r_tuple_of_r_binaryANDr_int32END 2022-04-01 03:25:30 root: INFO: instruction count: 18: __C452etypeDecode.__m456read_fields_group_0 2022-04-01 03:25:30 root: INFO: instruction count: 34: __C452etypeDecode.__m457INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:30 root: INFO: instruction count: 11: __C452etypeDecode.__m458INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:25:30 root: INFO: instruction count: 58: __C452etypeDecode.__m459INPLACE_DECODE_r_array_of_r_binary_TO_r_array_of_r_binary 2022-04-01 03:25:30 root: INFO: instruction count: 10: __C452etypeDecode.__m460SKIP_o_binary 2022-04-01 03:25:30 root: INFO: instruction count: 6: __C452etypeDecode.__m461SKIP_o_float64 2022-04-01 03:25:30 root: INFO: instruction count: 28: __C452etypeDecode.__m462SKIP_o_array_of_r_binary 2022-04-01 03:25:30 root: INFO: instruction count: 10: __C452etypeDecode.__m463SKIP_r_binary 2022-04-01 03:25:30 root: INFO: instruction count: 48: __C452etypeDecode.__m464INPLACE_DECODE_r_struct_of_o_float64ANDo_float64ANDo_float64ANDo_int32ANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_int32END_TO_r_tuple_of_o_array_of_o_binaryEND 2022-04-01 03:25:30 root: INFO: instruction count: 347: __C452etypeDecode.__m465read_fields_group_0 2022-04-01 03:25:30 root: INFO: instruction count: 6: __C452etypeDecode.__m466SKIP_o_int32 2022-04-01 03:25:30 root: INFO: instruction count: 59: __C452etypeDecode.__m467SKIP_o_array_of_o_binary 2022-04-01 03:25:30 root: INFO: instruction count: 105: __C452etypeDecode.__m468INPLACE_DECODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:25:30 root: INFO: instruction count: 34: __C452etypeDecode.__m469INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:25:30 root: INFO: instruction count: 6: __C452etypeDecode.__m470SKIP_r_int32 2022-04-01 03:25:30 root: INFO: instruction count: 6: __C452etypeDecode.__m471SKIP_r_bool 2022-04-01 03:25:30 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:30 root: INFO: decoder cache hit 2022-04-01 03:25:30 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/parts/part-0' for reading 2022-04-01 03:25:30 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:30 root: INFO: decoder cache miss (2 hits, 10 misses, 0.167 2022-04-01 03:25:30 root: INFO: instruction count: 6: __C472etypeDecode. 2022-04-01 03:25:30 root: INFO: instruction count: 8: __C472etypeDecode.apply 2022-04-01 03:25:30 root: INFO: instruction count: 38: __C472etypeDecode.__m473DECODE_r_struct_of_r_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryANDo_binaryANDo_float64ANDo_array_of_r_binaryANDr_struct_of_o_float64ANDo_float64ANDo_float64ANDo_int32ANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_int32ENDANDo_array_of_r_binaryANDr_int32ANDr_boolANDo_int32END_TO_r_tuple_of_r_locusANDr_array_of_r_stringANDo_int32END 2022-04-01 03:25:30 root: INFO: instruction count: 118: __C472etypeDecode.__m474read_fields_group_0 2022-04-01 03:25:30 root: INFO: instruction count: 17: __C472etypeDecode.__m475INPLACE_DECODE_r_struct_of_r_binaryANDr_int32END_TO_r_tuple_of_r_binaryANDr_int32END 2022-04-01 03:25:30 root: INFO: instruction count: 18: __C472etypeDecode.__m476read_fields_group_0 2022-04-01 03:25:30 root: INFO: instruction count: 34: __C472etypeDecode.__m477INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:30 root: INFO: instruction count: 11: __C472etypeDecode.__m478INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:25:30 root: INFO: instruction count: 58: __C472etypeDecode.__m479INPLACE_DECODE_r_array_of_r_binary_TO_r_array_of_r_binary 2022-04-01 03:25:30 root: INFO: instruction count: 10: __C472etypeDecode.__m480SKIP_o_binary 2022-04-01 03:25:30 root: INFO: instruction count: 6: __C472etypeDecode.__m481SKIP_o_float64 2022-04-01 03:25:30 root: INFO: instruction count: 28: __C472etypeDecode.__m482SKIP_o_array_of_r_binary 2022-04-01 03:25:30 root: INFO: instruction count: 10: __C472etypeDecode.__m483SKIP_r_binary 2022-04-01 03:25:30 root: INFO: instruction count: 372: __C472etypeDecode.__m484SKIP_r_struct_of_o_float64ANDo_float64ANDo_float64ANDo_int32ANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_int32END 2022-04-01 03:25:30 root: INFO: instruction count: 6: __C472etypeDecode.__m485SKIP_o_int32 2022-04-01 03:25:30 root: INFO: instruction count: 59: __C472etypeDecode.__m486SKIP_o_array_of_o_binary 2022-04-01 03:25:30 root: INFO: instruction count: 6: __C472etypeDecode.__m487SKIP_r_int32 2022-04-01 03:25:30 root: INFO: instruction count: 6: __C472etypeDecode.__m488SKIP_r_bool 2022-04-01 03:25:30 root: INFO: instruction count: 11: __C472etypeDecode.__m489INPLACE_DECODE_o_int32_TO_o_int32 2022-04-01 03:25:31 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:32 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:32 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:33 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:33 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:33 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:33 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:33 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.199ms, total 16.066s 2022-04-01 03:25:33 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 306: (Coalesce (InsertFields (Let __iruid_4294 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)) (Let __iruid_4295 (GetField vep (Ref __iruid_4294)) (Let __iruid_4296 (ToArray (StreamMap __iruid_4297 (ToStream False (ArraySort __iruid_4298 __iruid_4299 (StreamMap __iruid_4300 (StreamFilter __iruid_4301 (StreamMap __iruid_4302 (ToStream False (GetField transcript_consequences (Ref __iruid_4295))) (Let __iruid_4303 (GetField consequence_terms (Ref __iruid_4302)) (InsertFields (SelectFields (biotype canonical cdna_start cdna_end codons gene_id gene_symbol hgvsc hgvsp transcript_id amino_acids lof lof_filter lof_flags lof_info polyphen_prediction protein_id protein_start sift_prediction) (Ref __iruid_4302)) None (consequence_terms (ToArray (StreamFilter __iruid_4304 (ToStream False (Ref __iruid_4303)) (ApplyUnaryPrimOp Bang (ApplyIR contains () Boolean (ToSet (ToStream False (Literal Array[String] ))) (Ref __iruid_4304)))))) (domains (ToArray (StreamMap __iruid_4305 (ToStream False (GetField domains (Ref __iruid_4302))) (Apply concat () String (Apply concat () String (GetField db (Ref __iruid_4305)) (Str ":")) (GetField name (Ref __iruid_4305)))))) (major_consequence (If (ApplyComparisonOp GT (ArrayLen (Ref __iruid_4303)) (I32 0)) (ApplyIR indexArray () String (ToArray (StreamMap __iruid_4306 (ToStream False (ArraySort __iruid_4307 __iruid_4308 (StreamMap __iruid_4309 (ToStream False (GetField consequence_terms (Ref __iruid_4302))) (MakeTuple (0 1) (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (Ref __iruid_4309)) (Ref __iruid_4309))) (If (IsNA (GetTupleElement 0 (Ref __iruid_4307))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_4308))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_4307)) (GetTupleElement 0 (Ref __iruid_4308))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_4306)))) (I32 0) (Str " File \"/h...")) (NA String)))))) (ApplyComparisonOp GT (ArrayLen (GetField consequence_terms (Ref __iruid_4301))) (I32 0))) (Let __iruid_4310 (GetField major_consequence (Ref __iruid_4300)) (Let __iruid_4311 (InsertFields (Ref __iruid_4300) None (category (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (Ref __iruid_4310)) (I32 4)) (Str "lof") (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (GetField major_consequence (Ref __iruid_4300))) (I32 11)) (Str "missense") (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (GetField major_consequence (Ref __iruid_4300))) (I32 17)) (Str "synonymous") (Str "other"))))) (hgvs (If (ApplySpecial lor () Boolean (IsNA (GetField hgvsp (Ref __iruid_4300))) (ApplyIR contains () Boolean (ToSet (ToStream False (Literal Array[String] ))) (Ref __iruid_4310))) (ApplyIR indexArray () String (Apply split () Array[String] (GetField hgvsc (Ref __iruid_4300)) (Str ":")) (I32 -1) (Str " File \"/h...")) (Let __iruid_4312 (GetField hgvsp (Ref __iruid_4300)) (If (ApplySpecial lor () Boolean (Apply contains () Boolean (Ref __iruid_4312) (Str "=")) (Apply contains () Boolean (Ref __iruid_4312) (Str "%3D"))) (Let __iruid_4313 (Apply mkString () String (ToArray (StreamMap __iruid_4314 (ToStream False (Apply split () Array[String] (GetField amino_acids (Ref __iruid_4300)) (Str ""))) (ApplyIR get () String (Literal Dict[String,String] ) (Ref __iruid_4314)))) (Str "")) (Apply concat () String (Apply concat () String (Apply concat () String (Str "p.") (Ref __iruid_4313)) (Apply str () String (GetField protein_start (Ref __iruid_4300)))) (Ref __iruid_4313))) (ApplyIR indexArray () String (Apply split () Array[String] (GetField hgvsp (Ref __iruid_4300)) (Str ":")) (I32 -1) (Str " File \"/h...")))))) (major_consequence_rank (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (Ref __iruid_4310)))) (MakeTuple (0 1) (Let __iruid_4315 (ApplyComparisonOp EQ (Coalesce (GetField canonical (Ref __iruid_4311)) (I32 0)) (I32 1)) (Let __iruid_4316 (ApplyIR contains () Boolean (ToSet (ToStream False (GetField consequence_terms (Ref __iruid_4311)))) (GetField most_severe_consequence (Ref __iruid_4295))) (If (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_4311)) (Str "")) (Str "protein_co...")) (If (Ref __iruid_4316) (If (Ref __iruid_4315) (I32 1) (I32 2)) (If (Ref __iruid_4315) (I32 3) (I32 4))) (If (Ref __iruid_4316) (If (Ref __iruid_4315) (I32 5) (I32 6)) (If (Ref __iruid_4315) (I32 7) (I32 8)))))) (Ref __iruid_4311))))) (If (IsNA (GetTupleElement 0 (Ref __iruid_4298))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_4299))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_4298)) (GetTupleElement 0 (Ref __iruid_4299))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_4297)))) (Let __iruid_4317 (ToArray (StreamMap __iruid_4318 (StreamRange False (I32 0) (ArrayLen (Ref __iruid_4296)) (I32 1)) (Let __iruid_4319 (MakeTuple (0 1) (Ref __iruid_4318) (ApplyIR indexArray () Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32} (Ref __iruid_4296) (Ref __iruid_4318) (Str " File \"/h..."))) (InsertFields (GetTupleElement 1 (Ref __iruid_4319)) None (transcript_rank (GetTupleElement 0 (Ref __iruid_4319))))))) (InsertFields (Ref __iruid_4294) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig") (clinvar (MakeStruct (allele_id (GetField ALLELEID (GetField info (GetField __uid_6 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1))))) (clinical_significance (Apply mkString () String (GetField CLNSIG (GetField info (GetField __uid_7 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))) (Str ","))) (gold_stars (GetField gold_stars (GetField __uid_8 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))))) (sortedTranscriptConsequences (Ref __iruid_4317)) (codingGeneIds (ToSet (StreamMap __iruid_4320 (StreamFilter __iruid_4321 (ToStream False (Ref __iruid_4317)) (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_4321)) (Str "")) (Str "protein_co..."))) (GetField gene_id (Ref __iruid_4320))))) (contig (Apply replace () String (Apply contig () String (GetField locus (Ref __iruid_4294))) (Str "^chr") (Str "")))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 2.474ms, total 16.073s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.996ms, total 16.074s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 3.261ms, total 16.078s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 17.264ms, total 16.095s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.715ms, total 16.096s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 31.310ms, total 16.127s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 1.315ms, total 16.129s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.978ms, total 16.130s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 3.186ms, total 16.133s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 37.647ms, total 16.171s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.725ms, total 16.172s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 21.050ms, total 16.193s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 1.224ms, total 16.194s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.989ms, total 16.195s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 7.227ms, total 16.203s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 11.141ms, total 16.214s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.716ms, total 16.215s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 24.902ms, total 16.240s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 168.994ms, total 16.240s, tagged coverage 98.9 2022-04-01 03:25:33 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 306: (Coalesce (InsertFields (Let __iruid_5351 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)) (Let __iruid_5352 (GetField vep (Ref __iruid_5351)) (Let __iruid_5353 (ToArray (StreamMap __iruid_5354 (ToStream False (ArraySort __iruid_5355 __iruid_5356 (StreamMap __iruid_5357 (StreamFilter __iruid_5358 (StreamMap __iruid_5359 (ToStream False (GetField transcript_consequences (Ref __iruid_5352))) (Let __iruid_5360 (GetField consequence_terms (Ref __iruid_5359)) (InsertFields (SelectFields (biotype canonical cdna_start cdna_end codons gene_id gene_symbol hgvsc hgvsp transcript_id amino_acids lof lof_filter lof_flags lof_info polyphen_prediction protein_id protein_start sift_prediction) (Ref __iruid_5359)) None (consequence_terms (ToArray (StreamFilter __iruid_5361 (ToStream False (Ref __iruid_5360)) (ApplyUnaryPrimOp Bang (ApplyIR contains () Boolean (ToSet (ToStream False (Literal Array[String] ))) (Ref __iruid_5361)))))) (domains (ToArray (StreamMap __iruid_5362 (ToStream False (GetField domains (Ref __iruid_5359))) (Apply concat () String (Apply concat () String (GetField db (Ref __iruid_5362)) (Str ":")) (GetField name (Ref __iruid_5362)))))) (major_consequence (If (ApplyComparisonOp GT (ArrayLen (Ref __iruid_5360)) (I32 0)) (ApplyIR indexArray () String (ToArray (StreamMap __iruid_5363 (ToStream False (ArraySort __iruid_5364 __iruid_5365 (StreamMap __iruid_5366 (ToStream False (GetField consequence_terms (Ref __iruid_5359))) (MakeTuple (0 1) (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (Ref __iruid_5366)) (Ref __iruid_5366))) (If (IsNA (GetTupleElement 0 (Ref __iruid_5364))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_5365))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_5364)) (GetTupleElement 0 (Ref __iruid_5365))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_5363)))) (I32 0) (Str " File \"/h...")) (NA String)))))) (ApplyComparisonOp GT (ArrayLen (GetField consequence_terms (Ref __iruid_5358))) (I32 0))) (Let __iruid_5367 (GetField major_consequence (Ref __iruid_5357)) (Let __iruid_5368 (InsertFields (Ref __iruid_5357) None (category (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (Ref __iruid_5367)) (I32 4)) (Str "lof") (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (GetField major_consequence (Ref __iruid_5357))) (I32 11)) (Str "missense") (If (ApplyComparisonOp LTEQ (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (GetField major_consequence (Ref __iruid_5357))) (I32 17)) (Str "synonymous") (Str "other"))))) (hgvs (If (ApplySpecial lor () Boolean (IsNA (GetField hgvsp (Ref __iruid_5357))) (ApplyIR contains () Boolean (ToSet (ToStream False (Literal Array[String] ))) (Ref __iruid_5367))) (ApplyIR indexArray () String (Apply split () Array[String] (GetField hgvsc (Ref __iruid_5357)) (Str ":")) (I32 -1) (Str " File \"/h...")) (Let __iruid_5369 (GetField hgvsp (Ref __iruid_5357)) (If (ApplySpecial lor () Boolean (Apply contains () Boolean (Ref __iruid_5369) (Str "=")) (Apply contains () Boolean (Ref __iruid_5369) (Str "%3D"))) (Let __iruid_5370 (Apply mkString () String (ToArray (StreamMap __iruid_5371 (ToStream False (Apply split () Array[String] (GetField amino_acids (Ref __iruid_5357)) (Str ""))) (ApplyIR get () String (Literal Dict[String,String] ) (Ref __iruid_5371)))) (Str "")) (Apply concat () String (Apply concat () String (Apply concat () String (Str "p.") (Ref __iruid_5370)) (Apply str () String (GetField protein_start (Ref __iruid_5357)))) (Ref __iruid_5370))) (ApplyIR indexArray () String (Apply split () Array[String] (GetField hgvsp (Ref __iruid_5357)) (Str ":")) (I32 -1) (Str " File \"/h...")))))) (major_consequence_rank (ApplyIR get () Int32 (Literal Dict[String,Int32] ) (Ref __iruid_5367)))) (MakeTuple (0 1) (Let __iruid_5372 (ApplyComparisonOp EQ (Coalesce (GetField canonical (Ref __iruid_5368)) (I32 0)) (I32 1)) (Let __iruid_5373 (ApplyIR contains () Boolean (ToSet (ToStream False (GetField consequence_terms (Ref __iruid_5368)))) (GetField most_severe_consequence (Ref __iruid_5352))) (If (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_5368)) (Str "")) (Str "protein_co...")) (If (Ref __iruid_5373) (If (Ref __iruid_5372) (I32 1) (I32 2)) (If (Ref __iruid_5372) (I32 3) (I32 4))) (If (Ref __iruid_5373) (If (Ref __iruid_5372) (I32 5) (I32 6)) (If (Ref __iruid_5372) (I32 7) (I32 8)))))) (Ref __iruid_5368))))) (If (IsNA (GetTupleElement 0 (Ref __iruid_5355))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_5356))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_5355)) (GetTupleElement 0 (Ref __iruid_5356))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_5354)))) (Let __iruid_5374 (ToArray (StreamMap __iruid_5375 (StreamRange False (I32 0) (ArrayLen (Ref __iruid_5353)) (I32 1)) (Let __iruid_5376 (MakeTuple (0 1) (Ref __iruid_5375) (ApplyIR indexArray () Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32} (Ref __iruid_5353) (Ref __iruid_5375) (Str " File \"/h..."))) (InsertFields (GetTupleElement 1 (Ref __iruid_5376)) None (transcript_rank (GetTupleElement 0 (Ref __iruid_5376))))))) (InsertFields (Ref __iruid_5351) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig") (clinvar (MakeStruct (allele_id (GetField ALLELEID (GetField info (GetField __uid_6 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1))))) (clinical_significance (Apply mkString () String (GetField CLNSIG (GetField info (GetField __uid_7 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))) (Str ","))) (gold_stars (GetField gold_stars (GetField __uid_8 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))))) (sortedTranscriptConsequences (Ref __iruid_5374)) (codingGeneIds (ToSet (StreamMap __iruid_5377 (StreamFilter __iruid_5378 (ToStream False (Ref __iruid_5374)) (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_5378)) (Str "")) (Str "protein_co..."))) (GetField gene_id (Ref __iruid_5377))))) (contig (Apply replace () String (Apply contig () String (GetField locus (Ref __iruid_5351))) (Str "^chr") (Str "")))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 181.913ms, total 16.248s, tagged coverage 91.9 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.146ms, total 16.248s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 182.509ms, total 16.248s, tagged coverage 91.8 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 2.218ms, total 16.252s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 5.287ms, total 16.257s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.746ms, total 16.258s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 8.481ms, total 16.258s, tagged coverage 97.3 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.988ms, total 16.262s 2022-04-01 03:25:33 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 623: (Coalesce (InsertFields (Let __iruid_5351 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)) (Let __iruid_5352 (GetField vep (Ref __iruid_5351)) (Let __iruid_5353 (ToArray (StreamMap __iruid_5354 (ToStream False (ArraySort __iruid_5355 __iruid_5356 (StreamMap __iruid_5357 (StreamFilter __iruid_5358 (StreamMap __iruid_5359 (ToStream False (GetField transcript_consequences (Ref __iruid_5352))) (Let __iruid_5360 (GetField consequence_terms (Ref __iruid_5359)) (InsertFields (SelectFields (biotype canonical cdna_start cdna_end codons gene_id gene_symbol hgvsc hgvsp transcript_id amino_acids lof lof_filter lof_flags lof_info polyphen_prediction protein_id protein_start sift_prediction) (Ref __iruid_5359)) None (consequence_terms (ToArray (StreamFilter __iruid_5361 (ToStream False (Ref __iruid_5360)) (ApplyUnaryPrimOp Bang (Let __iruid_5490 (ToSet (ToStream False (Literal Array[String] ))) (Let __iruid_5491 (Ref __iruid_5361) (If (IsNA (Ref __iruid_5490)) (NA Boolean) (Let __iruid_5492 (LowerBoundOnOrderedCollection False (Ref __iruid_5490) (Ref __iruid_5491)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5492) (ArrayLen (CastToArray (Ref __iruid_5490)))) (False) (ApplyComparisonOp EQWithNA (ArrayRef (CastToArray (Ref __iruid_5490)) (Ref __iruid_5492) (Str "")) (Ref __iruid_5491))))))))))) (domains (ToArray (StreamMap __iruid_5362 (ToStream False (GetField domains (Ref __iruid_5359))) (Apply concat () String (Apply concat () String (GetField db (Ref __iruid_5362)) (Str ":")) (GetField name (Ref __iruid_5362)))))) (major_consequence (If (ApplyComparisonOp GT (ArrayLen (Ref __iruid_5360)) (I32 0)) (Let __iruid_5493 (ToArray (StreamMap __iruid_5363 (ToStream False (ArraySort __iruid_5364 __iruid_5365 (StreamMap __iruid_5366 (ToStream False (GetField consequence_terms (Ref __iruid_5359))) (MakeTuple (0 1) (Let __iruid_5454 (Literal Dict[String,Int32] ) (Let __iruid_5455 (Ref __iruid_5366) (If (IsNA (Ref __iruid_5454)) (NA Int32) (Let __iruid_5456 (LowerBoundOnOrderedCollection True (Ref __iruid_5454) (Ref __iruid_5455)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5456) (ArrayLen (CastToArray (Ref __iruid_5454)))) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (CastToArray (Ref __iruid_5454)) (Ref __iruid_5456) (Str ""))) (Ref __iruid_5455)) (GetField value (ArrayRef (CastToArray (Ref __iruid_5454)) (Ref __iruid_5456) (Str ""))) (NA Int32))))))) (Ref __iruid_5366))) (If (IsNA (GetTupleElement 0 (Ref __iruid_5364))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_5365))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_5364)) (GetTupleElement 0 (Ref __iruid_5365))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_5363)))) (Let __iruid_5494 (I32 0) (Let __iruid_5495 (Str " File \"/h...") (ArrayRef (Ref __iruid_5493) (If (ApplyComparisonOp LT (Ref __iruid_5494) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_5493)) (Ref __iruid_5494)) (Ref __iruid_5494)) (Ref __iruid_5495))))) (NA String)))))) (ApplyComparisonOp GT (ArrayLen (GetField consequence_terms (Ref __iruid_5358))) (I32 0))) (Let __iruid_5367 (GetField major_consequence (Ref __iruid_5357)) (Let __iruid_5368 (InsertFields (Ref __iruid_5357) None (category (If (ApplyComparisonOp LTEQ (Let __iruid_5475 (Literal Dict[String,Int32] ) (Let __iruid_5476 (Ref __iruid_5367) (If (IsNA (Ref __iruid_5475)) (NA Int32) (Let __iruid_5477 (LowerBoundOnOrderedCollection True (Ref __iruid_5475) (Ref __iruid_5476)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5477) (ArrayLen (CastToArray (Ref __iruid_5475)))) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (CastToArray (Ref __iruid_5475)) (Ref __iruid_5477) (Str ""))) (Ref __iruid_5476)) (GetField value (ArrayRef (CastToArray (Ref __iruid_5475)) (Ref __iruid_5477) (Str ""))) (NA Int32))))))) (I32 4)) (Str "lof") (If (ApplyComparisonOp LTEQ (Let __iruid_5463 (Literal Dict[String,Int32] ) (Let __iruid_5464 (GetField major_consequence (Ref __iruid_5357)) (If (IsNA (Ref __iruid_5463)) (NA Int32) (Let __iruid_5465 (LowerBoundOnOrderedCollection True (Ref __iruid_5463) (Ref __iruid_5464)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5465) (ArrayLen (CastToArray (Ref __iruid_5463)))) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (CastToArray (Ref __iruid_5463)) (Ref __iruid_5465) (Str ""))) (Ref __iruid_5464)) (GetField value (ArrayRef (CastToArray (Ref __iruid_5463)) (Ref __iruid_5465) (Str ""))) (NA Int32))))))) (I32 11)) (Str "missense") (If (ApplyComparisonOp LTEQ (Let __iruid_5460 (Literal Dict[String,Int32] ) (Let __iruid_5461 (GetField major_consequence (Ref __iruid_5357)) (If (IsNA (Ref __iruid_5460)) (NA Int32) (Let __iruid_5462 (LowerBoundOnOrderedCollection True (Ref __iruid_5460) (Ref __iruid_5461)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5462) (ArrayLen (CastToArray (Ref __iruid_5460)))) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (CastToArray (Ref __iruid_5460)) (Ref __iruid_5462) (Str ""))) (Ref __iruid_5461)) (GetField value (ArrayRef (CastToArray (Ref __iruid_5460)) (Ref __iruid_5462) (Str ""))) (NA Int32))))))) (I32 17)) (Str "synonymous") (Str "other"))))) (hgvs (If (ApplySpecial lor () Boolean (IsNA (GetField hgvsp (Ref __iruid_5357))) (Let __iruid_5478 (ToSet (ToStream False (Literal Array[String] ))) (Let __iruid_5479 (Ref __iruid_5367) (If (IsNA (Ref __iruid_5478)) (NA Boolean) (Let __iruid_5480 (LowerBoundOnOrderedCollection False (Ref __iruid_5478) (Ref __iruid_5479)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5480) (ArrayLen (CastToArray (Ref __iruid_5478)))) (False) (ApplyComparisonOp EQWithNA (ArrayRef (CastToArray (Ref __iruid_5478)) (Ref __iruid_5480) (Str "")) (Ref __iruid_5479)))))))) (Let __iruid_5472 (Apply split () Array[String] (GetField hgvsc (Ref __iruid_5357)) (Str ":")) (Let __iruid_5473 (I32 -1) (Let __iruid_5474 (Str " File \"/h...") (ArrayRef (Ref __iruid_5472) (If (ApplyComparisonOp LT (Ref __iruid_5473) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_5472)) (Ref __iruid_5473)) (Ref __iruid_5473)) (Ref __iruid_5474))))) (Let __iruid_5369 (GetField hgvsp (Ref __iruid_5357)) (If (ApplySpecial lor () Boolean (Apply contains () Boolean (Ref __iruid_5369) (Str "=")) (Apply contains () Boolean (Ref __iruid_5369) (Str "%3D"))) (Let __iruid_5370 (Apply mkString () String (ToArray (StreamMap __iruid_5371 (ToStream False (Apply split () Array[String] (GetField amino_acids (Ref __iruid_5357)) (Str ""))) (Let __iruid_5466 (Literal Dict[String,String] ) (Let __iruid_5467 (Ref __iruid_5371) (If (IsNA (Ref __iruid_5466)) (NA String) (Let __iruid_5468 (LowerBoundOnOrderedCollection True (Ref __iruid_5466) (Ref __iruid_5467)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5468) (ArrayLen (CastToArray (Ref __iruid_5466)))) (NA String) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (CastToArray (Ref __iruid_5466)) (Ref __iruid_5468) (Str ""))) (Ref __iruid_5467)) (GetField value (ArrayRef (CastToArray (Ref __iruid_5466)) (Ref __iruid_5468) (Str ""))) (NA String))))))))) (Str "")) (Apply concat () String (Apply concat () String (Apply concat () String (Str "p.") (Ref __iruid_5370)) (Apply str () String (GetField protein_start (Ref __iruid_5357)))) (Ref __iruid_5370))) (Let __iruid_5469 (Apply split () Array[String] (GetField hgvsp (Ref __iruid_5357)) (Str ":")) (Let __iruid_5470 (I32 -1) (Let __iruid_5471 (Str " File \"/h...") (ArrayRef (Ref __iruid_5469) (If (ApplyComparisonOp LT (Ref __iruid_5470) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_5469)) (Ref __iruid_5470)) (Ref __iruid_5470)) (Ref __iruid_5471))))))))) (major_consequence_rank (Let __iruid_5481 (Literal Dict[String,Int32] ) (Let __iruid_5482 (Ref __iruid_5367) (If (IsNA (Ref __iruid_5481)) (NA Int32) (Let __iruid_5483 (LowerBoundOnOrderedCollection True (Ref __iruid_5481) (Ref __iruid_5482)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5483) (ArrayLen (CastToArray (Ref __iruid_5481)))) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (CastToArray (Ref __iruid_5481)) (Ref __iruid_5483) (Str ""))) (Ref __iruid_5482)) (GetField value (ArrayRef (CastToArray (Ref __iruid_5481)) (Ref __iruid_5483) (Str ""))) (NA Int32))))))))) (MakeTuple (0 1) (Let __iruid_5372 (ApplyComparisonOp EQ (Coalesce (GetField canonical (Ref __iruid_5368)) (I32 0)) (I32 1)) (Let __iruid_5373 (Let __iruid_5484 (ToSet (ToStream False (GetField consequence_terms (Ref __iruid_5368)))) (Let __iruid_5485 (GetField most_severe_consequence (Ref __iruid_5352)) (If (IsNA (Ref __iruid_5484)) (NA Boolean) (Let __iruid_5486 (LowerBoundOnOrderedCollection False (Ref __iruid_5484) (Ref __iruid_5485)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5486) (ArrayLen (CastToArray (Ref __iruid_5484)))) (False) (ApplyComparisonOp EQWithNA (ArrayRef (CastToArray (Ref __iruid_5484)) (Ref __iruid_5486) (Str "")) (Ref __iruid_5485))))))) (If (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_5368)) (Str "")) (Str "protein_co...")) (If (Ref __iruid_5373) (If (Ref __iruid_5372) (I32 1) (I32 2)) (If (Ref __iruid_5372) (I32 3) (I32 4))) (If (Ref __iruid_5373) (If (Ref __iruid_5372) (I32 5) (I32 6)) (If (Ref __iruid_5372) (I32 7) (I32 8)))))) (Ref __iruid_5368))))) (If (IsNA (GetTupleElement 0 (Ref __iruid_5355))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_5356))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_5355)) (GetTupleElement 0 (Ref __iruid_5356))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_5354)))) (Let __iruid_5374 (ToArray (StreamMap __iruid_5375 (StreamRange False (I32 0) (ArrayLen (Ref __iruid_5353)) (I32 1)) (Let __iruid_5376 (MakeTuple (0 1) (Ref __iruid_5375) (Let __iruid_5487 (Ref __iruid_5353) (Let __iruid_5488 (Ref __iruid_5375) (Let __iruid_5489 (Str " File \"/h...") (ArrayRef (Ref __iruid_5487) (If (ApplyComparisonOp LT (Ref __iruid_5488) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_5487)) (Ref __iruid_5488)) (Ref __iruid_5488)) (Ref __iruid_5489)))))) (InsertFields (GetTupleElement 1 (Ref __iruid_5376)) None (transcript_rank (GetTupleElement 0 (Ref __iruid_5376))))))) (InsertFields (Ref __iruid_5351) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig") (clinvar (MakeStruct (allele_id (GetField ALLELEID (GetField info (GetField __uid_6 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1))))) (clinical_significance (Apply mkString () String (GetField CLNSIG (GetField info (GetField __uid_7 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))) (Str ","))) (gold_stars (GetField gold_stars (GetField __uid_8 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))))) (sortedTranscriptConsequences (Ref __iruid_5374)) (codingGeneIds (ToSet (StreamMap __iruid_5377 (StreamFilter __iruid_5378 (ToStream False (Ref __iruid_5374)) (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_5378)) (Str "")) (Str "protein_co..."))) (GetField gene_id (Ref __iruid_5377))))) (contig (Apply replace () String (Apply contig () String (GetField locus (Ref __iruid_5351))) (Str "^chr") (Str "")))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 1.464ms, total 16.269s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 10.149ms, total 16.279s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 3.853ms, total 16.283s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 18.689ms, total 16.302s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 2.149ms, total 16.304s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 27.294ms, total 16.332s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 5.247ms, total 16.337s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 5.715ms, total 16.343s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 4.640ms, total 16.348s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 11.900ms, total 16.360s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 2.023ms, total 16.362s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 14.121ms, total 16.376s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 2.210ms, total 16.378s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 1.037ms, total 16.379s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 3.638ms, total 16.383s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 10.567ms, total 16.394s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 1.774ms, total 16.396s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 16.010ms, total 16.412s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 144.239ms, total 16.412s, tagged coverage 98.8 2022-04-01 03:25:33 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 513: (Coalesce (InsertFields (Let __iruid_5609 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)) (Let __iruid_5610 (GetField vep (Ref __iruid_5609)) (Let __iruid_5611 (ToArray (StreamMap __iruid_5612 (ToStream False (ArraySort __iruid_5613 __iruid_5614 (StreamMap __iruid_5615 (StreamFilter __iruid_5616 (StreamMap __iruid_5617 (ToStream False (GetField transcript_consequences (Ref __iruid_5610))) (Let __iruid_5618 (GetField consequence_terms (Ref __iruid_5617)) (InsertFields (SelectFields (biotype canonical cdna_start cdna_end codons gene_id gene_symbol hgvsc hgvsp transcript_id amino_acids lof lof_filter lof_flags lof_info polyphen_prediction protein_id protein_start sift_prediction) (Ref __iruid_5617)) None (consequence_terms (ToArray (StreamFilter __iruid_5619 (ToStream False (Ref __iruid_5618)) (ApplyUnaryPrimOp Bang (Let __iruid_5620 (ToSet (ToStream False (Literal Array[String] ))) (If (IsNA (Ref __iruid_5620)) (NA Boolean) (Let __iruid_5621 (LowerBoundOnOrderedCollection False (Ref __iruid_5620) (Ref __iruid_5619)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5621) (ArrayLen (CastToArray (Ref __iruid_5620)))) (False) (ApplyComparisonOp EQWithNA (ArrayRef (CastToArray (Ref __iruid_5620)) (Ref __iruid_5621) (Str "")) (Ref __iruid_5619)))))))))) (domains (ToArray (StreamMap __iruid_5622 (ToStream False (GetField domains (Ref __iruid_5617))) (Apply concat () String (Apply concat () String (GetField db (Ref __iruid_5622)) (Str ":")) (GetField name (Ref __iruid_5622)))))) (major_consequence (If (ApplyComparisonOp GT (ArrayLen (Ref __iruid_5618)) (I32 0)) (ArrayRef (ToArray (StreamMap __iruid_5623 (ToStream False (ArraySort __iruid_5624 __iruid_5625 (StreamMap __iruid_5626 (ToStream False (GetField consequence_terms (Ref __iruid_5617))) (MakeTuple (0 1) (Let __iruid_5627 (LowerBoundOnOrderedCollection True (Literal Dict[String,Int32] ) (Ref __iruid_5626)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5627) (I32 39)) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5627) (Str ""))) (Ref __iruid_5626)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5627) (Str ""))) (NA Int32)))) (Ref __iruid_5626))) (If (IsNA (GetTupleElement 0 (Ref __iruid_5624))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_5625))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_5624)) (GetTupleElement 0 (Ref __iruid_5625))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_5623)))) (I32 0) (Str " File \"/h...")) (NA String)))))) (ApplyComparisonOp GT (ArrayLen (GetField consequence_terms (Ref __iruid_5616))) (I32 0))) (Let __iruid_5628 (GetField major_consequence (Ref __iruid_5615)) (Let __iruid_5629 (InsertFields (Ref __iruid_5615) None (category (If (ApplyComparisonOp LTEQ (Let __iruid_5630 (LowerBoundOnOrderedCollection True (Literal Dict[String,Int32] ) (Ref __iruid_5628)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5630) (I32 39)) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5630) (Str ""))) (Ref __iruid_5628)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5630) (Str ""))) (NA Int32)))) (I32 4)) (Str "lof") (If (ApplyComparisonOp LTEQ (Let __iruid_5631 (GetField major_consequence (Ref __iruid_5615)) (Let __iruid_5632 (LowerBoundOnOrderedCollection True (Literal Dict[String,Int32] ) (Ref __iruid_5631)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5632) (I32 39)) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5632) (Str ""))) (Ref __iruid_5631)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5632) (Str ""))) (NA Int32))))) (I32 11)) (Str "missense") (If (ApplyComparisonOp LTEQ (Let __iruid_5633 (GetField major_consequence (Ref __iruid_5615)) (Let __iruid_5634 (LowerBoundOnOrderedCollection True (Literal Dict[String,Int32] ) (Ref __iruid_5633)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5634) (I32 39)) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5634) (Str ""))) (Ref __iruid_5633)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5634) (Str ""))) (NA Int32))))) (I32 17)) (Str "synonymous") (Str "other"))))) (hgvs (If (ApplySpecial lor () Boolean (IsNA (GetField hgvsp (Ref __iruid_5615))) (Let __iruid_5635 (ToSet (ToStream False (Literal Array[String] ))) (If (IsNA (Ref __iruid_5635)) (NA Boolean) (Let __iruid_5636 (LowerBoundOnOrderedCollection False (Ref __iruid_5635) (Ref __iruid_5628)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5636) (ArrayLen (CastToArray (Ref __iruid_5635)))) (False) (ApplyComparisonOp EQWithNA (ArrayRef (CastToArray (Ref __iruid_5635)) (Ref __iruid_5636) (Str "")) (Ref __iruid_5628))))))) (Let __iruid_5637 (Apply split () Array[String] (GetField hgvsc (Ref __iruid_5615)) (Str ":")) (ArrayRef (Ref __iruid_5637) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_5637)) (I32 -1)) (Str " File \"/h..."))) (Let __iruid_5638 (GetField hgvsp (Ref __iruid_5615)) (If (ApplySpecial lor () Boolean (Apply contains () Boolean (Ref __iruid_5638) (Str "=")) (Apply contains () Boolean (Ref __iruid_5638) (Str "%3D"))) (Let __iruid_5639 (Apply mkString () String (ToArray (StreamMap __iruid_5640 (ToStream False (Apply split () Array[String] (GetField amino_acids (Ref __iruid_5615)) (Str ""))) (Let __iruid_5641 (LowerBoundOnOrderedCollection True (Literal Dict[String,String] ) (Ref __iruid_5640)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5641) (I32 23)) (NA String) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:String}] ) (Ref __iruid_5641) (Str ""))) (Ref __iruid_5640)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:String}] ) (Ref __iruid_5641) (Str ""))) (NA String)))))) (Str "")) (Apply concat () String (Apply concat () String (Apply concat () String (Str "p.") (Ref __iruid_5639)) (Apply str () String (GetField protein_start (Ref __iruid_5615)))) (Ref __iruid_5639))) (Let __iruid_5642 (Apply split () Array[String] (GetField hgvsp (Ref __iruid_5615)) (Str ":")) (ArrayRef (Ref __iruid_5642) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_5642)) (I32 -1)) (Str " File \"/h..."))))))) (major_consequence_rank (Let __iruid_5643 (LowerBoundOnOrderedCollection True (Literal Dict[String,Int32] ) (Ref __iruid_5628)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5643) (I32 39)) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5643) (Str ""))) (Ref __iruid_5628)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5643) (Str ""))) (NA Int32)))))) (MakeTuple (0 1) (Let __iruid_5644 (ApplyComparisonOp EQ (Coalesce (GetField canonical (Ref __iruid_5629)) (I32 0)) (I32 1)) (Let __iruid_5645 (ToSet (ToStream False (GetField consequence_terms (Ref __iruid_5629)))) (Let __iruid_5646 (GetField most_severe_consequence (Ref __iruid_5610)) (Let __iruid_5647 (If (IsNA (Ref __iruid_5645)) (NA Boolean) (Let __iruid_5648 (LowerBoundOnOrderedCollection False (Ref __iruid_5645) (Ref __iruid_5646)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5648) (ArrayLen (CastToArray (Ref __iruid_5645)))) (False) (ApplyComparisonOp EQWithNA (ArrayRef (CastToArray (Ref __iruid_5645)) (Ref __iruid_5648) (Str "")) (Ref __iruid_5646))))) (If (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_5629)) (Str "")) (Str "protein_co...")) (If (Ref __iruid_5647) (If (Ref __iruid_5644) (I32 1) (I32 2)) (If (Ref __iruid_5644) (I32 3) (I32 4))) (If (Ref __iruid_5647) (If (Ref __iruid_5644) (I32 5) (I32 6)) (If (Ref __iruid_5644) (I32 7) (I32 8)))))))) (Ref __iruid_5629))))) (If (IsNA (GetTupleElement 0 (Ref __iruid_5613))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_5614))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_5613)) (GetTupleElement 0 (Ref __iruid_5614))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_5612)))) (Let __iruid_5649 (ToArray (StreamMap __iruid_5650 (StreamRange False (I32 0) (ArrayLen (Ref __iruid_5611)) (I32 1)) (Let __iruid_5651 (MakeTuple (0 1) (Ref __iruid_5650) (ArrayRef (Ref __iruid_5611) (If (ApplyComparisonOp LT (Ref __iruid_5650) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_5611)) (Ref __iruid_5650)) (Ref __iruid_5650)) (Str " File \"/h..."))) (InsertFields (GetTupleElement 1 (Ref __iruid_5651)) None (transcript_rank (GetTupleElement 0 (Ref __iruid_5651))))))) (InsertFields (Ref __iruid_5609) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig") (clinvar (MakeStruct (allele_id (GetField ALLELEID (GetField info (GetField __uid_6 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1))))) (clinical_significance (Apply mkString () String (GetField CLNSIG (GetField info (GetField __uid_7 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))) (Str ","))) (gold_stars (GetField gold_stars (GetField __uid_8 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))))) (sortedTranscriptConsequences (Ref __iruid_5649)) (codingGeneIds (ToSet (StreamMap __iruid_5652 (StreamFilter __iruid_5653 (ToStream False (Ref __iruid_5649)) (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_5653)) (Str "")) (Str "protein_co..."))) (GetField gene_id (Ref __iruid_5652))))) (contig (Apply replace () String (Apply contig () String (GetField locus (Ref __iruid_5609))) (Str "^chr") (Str "")))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 154.973ms, total 16.417s, tagged coverage 91.9 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.093ms, total 16.418s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 156.230ms, total 16.418s, tagged coverage 91.9 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.216ms, total 16.420s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 52.238ms, total 16.473s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 1.285ms, total 16.474s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 54.017ms, total 16.474s, tagged coverage 99.5 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.044ms, total 16.481s 2022-04-01 03:25:33 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 513: (Coalesce (InsertFields (Let __iruid_5609 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)) (Let __iruid_5610 (GetField vep (Ref __iruid_5609)) (Let __iruid_5611 (ToArray (StreamMap __iruid_5612 (ToStream False (ArraySort __iruid_5613 __iruid_5614 (StreamMap __iruid_5615 (StreamFilter __iruid_5616 (StreamMap __iruid_5617 (ToStream False (GetField transcript_consequences (Ref __iruid_5610))) (Let __iruid_5618 (GetField consequence_terms (Ref __iruid_5617)) (InsertFields (SelectFields (biotype canonical cdna_start cdna_end codons gene_id gene_symbol hgvsc hgvsp transcript_id amino_acids lof lof_filter lof_flags lof_info polyphen_prediction protein_id protein_start sift_prediction) (Ref __iruid_5617)) None (consequence_terms (ToArray (StreamFilter __iruid_5619 (ToStream False (Ref __iruid_5618)) (ApplyUnaryPrimOp Bang (Let __iruid_5620 (ToSet (ToStream False (Literal Array[String] ))) (If (IsNA (Ref __iruid_5620)) (NA Boolean) (Let __iruid_5621 (LowerBoundOnOrderedCollection False (Ref __iruid_5620) (Ref __iruid_5619)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5621) (ArrayLen (CastToArray (Ref __iruid_5620)))) (False) (ApplyComparisonOp EQWithNA (ArrayRef (CastToArray (Ref __iruid_5620)) (Ref __iruid_5621) (Str "")) (Ref __iruid_5619)))))))))) (domains (ToArray (StreamMap __iruid_5622 (ToStream False (GetField domains (Ref __iruid_5617))) (Apply concat () String (Apply concat () String (GetField db (Ref __iruid_5622)) (Str ":")) (GetField name (Ref __iruid_5622)))))) (major_consequence (If (ApplyComparisonOp GT (ArrayLen (Ref __iruid_5618)) (I32 0)) (ArrayRef (ToArray (StreamMap __iruid_5623 (ToStream False (ArraySort __iruid_5624 __iruid_5625 (StreamMap __iruid_5626 (ToStream False (GetField consequence_terms (Ref __iruid_5617))) (MakeTuple (0 1) (Let __iruid_5627 (LowerBoundOnOrderedCollection True (Literal Dict[String,Int32] ) (Ref __iruid_5626)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5627) (I32 39)) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5627) (Str ""))) (Ref __iruid_5626)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5627) (Str ""))) (NA Int32)))) (Ref __iruid_5626))) (If (IsNA (GetTupleElement 0 (Ref __iruid_5624))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_5625))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_5624)) (GetTupleElement 0 (Ref __iruid_5625))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_5623)))) (I32 0) (Str " File \"/h...")) (NA String)))))) (ApplyComparisonOp GT (ArrayLen (GetField consequence_terms (Ref __iruid_5616))) (I32 0))) (Let __iruid_5628 (GetField major_consequence (Ref __iruid_5615)) (Let __iruid_5629 (InsertFields (Ref __iruid_5615) None (category (If (ApplyComparisonOp LTEQ (Let __iruid_5630 (LowerBoundOnOrderedCollection True (Literal Dict[String,Int32] ) (Ref __iruid_5628)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5630) (I32 39)) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5630) (Str ""))) (Ref __iruid_5628)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5630) (Str ""))) (NA Int32)))) (I32 4)) (Str "lof") (If (ApplyComparisonOp LTEQ (Let __iruid_5631 (GetField major_consequence (Ref __iruid_5615)) (Let __iruid_5632 (LowerBoundOnOrderedCollection True (Literal Dict[String,Int32] ) (Ref __iruid_5631)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5632) (I32 39)) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5632) (Str ""))) (Ref __iruid_5631)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5632) (Str ""))) (NA Int32))))) (I32 11)) (Str "missense") (If (ApplyComparisonOp LTEQ (Let __iruid_5633 (GetField major_consequence (Ref __iruid_5615)) (Let __iruid_5634 (LowerBoundOnOrderedCollection True (Literal Dict[String,Int32] ) (Ref __iruid_5633)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5634) (I32 39)) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5634) (Str ""))) (Ref __iruid_5633)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5634) (Str ""))) (NA Int32))))) (I32 17)) (Str "synonymous") (Str "other"))))) (hgvs (If (ApplySpecial lor () Boolean (IsNA (GetField hgvsp (Ref __iruid_5615))) (Let __iruid_5635 (ToSet (ToStream False (Literal Array[String] ))) (If (IsNA (Ref __iruid_5635)) (NA Boolean) (Let __iruid_5636 (LowerBoundOnOrderedCollection False (Ref __iruid_5635) (Ref __iruid_5628)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5636) (ArrayLen (CastToArray (Ref __iruid_5635)))) (False) (ApplyComparisonOp EQWithNA (ArrayRef (CastToArray (Ref __iruid_5635)) (Ref __iruid_5636) (Str "")) (Ref __iruid_5628))))))) (Let __iruid_5637 (Apply split () Array[String] (GetField hgvsc (Ref __iruid_5615)) (Str ":")) (ArrayRef (Ref __iruid_5637) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_5637)) (I32 -1)) (Str " File \"/h..."))) (Let __iruid_5638 (GetField hgvsp (Ref __iruid_5615)) (If (ApplySpecial lor () Boolean (Apply contains () Boolean (Ref __iruid_5638) (Str "=")) (Apply contains () Boolean (Ref __iruid_5638) (Str "%3D"))) (Let __iruid_5639 (Apply mkString () String (ToArray (StreamMap __iruid_5640 (ToStream False (Apply split () Array[String] (GetField amino_acids (Ref __iruid_5615)) (Str ""))) (Let __iruid_5641 (LowerBoundOnOrderedCollection True (Literal Dict[String,String] ) (Ref __iruid_5640)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5641) (I32 23)) (NA String) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:String}] ) (Ref __iruid_5641) (Str ""))) (Ref __iruid_5640)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:String}] ) (Ref __iruid_5641) (Str ""))) (NA String)))))) (Str "")) (Apply concat () String (Apply concat () String (Apply concat () String (Str "p.") (Ref __iruid_5639)) (Apply str () String (GetField protein_start (Ref __iruid_5615)))) (Ref __iruid_5639))) (Let __iruid_5642 (Apply split () Array[String] (GetField hgvsp (Ref __iruid_5615)) (Str ":")) (ArrayRef (Ref __iruid_5642) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_5642)) (I32 -1)) (Str " File \"/h..."))))))) (major_consequence_rank (Let __iruid_5643 (LowerBoundOnOrderedCollection True (Literal Dict[String,Int32] ) (Ref __iruid_5628)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5643) (I32 39)) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5643) (Str ""))) (Ref __iruid_5628)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5643) (Str ""))) (NA Int32)))))) (MakeTuple (0 1) (Let __iruid_5644 (ApplyComparisonOp EQ (Coalesce (GetField canonical (Ref __iruid_5629)) (I32 0)) (I32 1)) (Let __iruid_5645 (ToSet (ToStream False (GetField consequence_terms (Ref __iruid_5629)))) (Let __iruid_5646 (GetField most_severe_consequence (Ref __iruid_5610)) (Let __iruid_5647 (If (IsNA (Ref __iruid_5645)) (NA Boolean) (Let __iruid_5648 (LowerBoundOnOrderedCollection False (Ref __iruid_5645) (Ref __iruid_5646)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5648) (ArrayLen (CastToArray (Ref __iruid_5645)))) (False) (ApplyComparisonOp EQWithNA (ArrayRef (CastToArray (Ref __iruid_5645)) (Ref __iruid_5648) (Str "")) (Ref __iruid_5646))))) (If (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_5629)) (Str "")) (Str "protein_co...")) (If (Ref __iruid_5647) (If (Ref __iruid_5644) (I32 1) (I32 2)) (If (Ref __iruid_5644) (I32 3) (I32 4))) (If (Ref __iruid_5647) (If (Ref __iruid_5644) (I32 5) (I32 6)) (If (Ref __iruid_5644) (I32 7) (I32 8)))))))) (Ref __iruid_5629))))) (If (IsNA (GetTupleElement 0 (Ref __iruid_5613))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_5614))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_5613)) (GetTupleElement 0 (Ref __iruid_5614))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_5612)))) (Let __iruid_5649 (ToArray (StreamMap __iruid_5650 (StreamRange False (I32 0) (ArrayLen (Ref __iruid_5611)) (I32 1)) (Let __iruid_5651 (MakeTuple (0 1) (Ref __iruid_5650) (ArrayRef (Ref __iruid_5611) (If (ApplyComparisonOp LT (Ref __iruid_5650) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_5611)) (Ref __iruid_5650)) (Ref __iruid_5650)) (Str " File \"/h..."))) (InsertFields (GetTupleElement 1 (Ref __iruid_5651)) None (transcript_rank (GetTupleElement 0 (Ref __iruid_5651))))))) (InsertFields (Ref __iruid_5609) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig") (clinvar (MakeStruct (allele_id (GetField ALLELEID (GetField info (GetField __uid_6 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1))))) (clinical_significance (Apply mkString () String (GetField CLNSIG (GetField info (GetField __uid_7 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))) (Str ","))) (gold_stars (GetField gold_stars (GetField __uid_8 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))))) (sortedTranscriptConsequences (Ref __iruid_5649)) (codingGeneIds (ToSet (StreamMap __iruid_5652 (StreamFilter __iruid_5653 (ToStream False (Ref __iruid_5649)) (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_5653)) (Str "")) (Str "protein_co..."))) (GetField gene_id (Ref __iruid_5652))))) (contig (Apply replace () String (Apply contig () String (GetField locus (Ref __iruid_5609))) (Str "^chr") (Str "")))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 1.345ms, total 16.489s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 1.076ms, total 16.490s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 3.704ms, total 16.494s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 22.002ms, total 16.516s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 1.749ms, total 16.518s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 14.212ms, total 16.532s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 2.002ms, total 16.534s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 1.024ms, total 16.535s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 3.993ms, total 16.539s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 11.663ms, total 16.551s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 1.672ms, total 16.553s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 14.456ms, total 16.567s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 1.943ms, total 16.569s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 1.988ms, total 16.572s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 4.034ms, total 16.576s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 8.841ms, total 16.585s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 1.655ms, total 16.586s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 14.318ms, total 16.601s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 113.197ms, total 16.601s, tagged coverage 98.7 2022-04-01 03:25:33 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 513: (Coalesce (InsertFields (Let __iruid_5744 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)) (Let __iruid_5745 (GetField vep (Ref __iruid_5744)) (Let __iruid_5746 (ToArray (StreamMap __iruid_5747 (ToStream False (ArraySort __iruid_5748 __iruid_5749 (StreamMap __iruid_5750 (StreamFilter __iruid_5751 (StreamMap __iruid_5752 (ToStream False (GetField transcript_consequences (Ref __iruid_5745))) (Let __iruid_5753 (GetField consequence_terms (Ref __iruid_5752)) (InsertFields (SelectFields (biotype canonical cdna_start cdna_end codons gene_id gene_symbol hgvsc hgvsp transcript_id amino_acids lof lof_filter lof_flags lof_info polyphen_prediction protein_id protein_start sift_prediction) (Ref __iruid_5752)) None (consequence_terms (ToArray (StreamFilter __iruid_5754 (ToStream False (Ref __iruid_5753)) (ApplyUnaryPrimOp Bang (Let __iruid_5755 (ToSet (ToStream False (Literal Array[String] ))) (If (IsNA (Ref __iruid_5755)) (NA Boolean) (Let __iruid_5756 (LowerBoundOnOrderedCollection False (Ref __iruid_5755) (Ref __iruid_5754)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5756) (ArrayLen (CastToArray (Ref __iruid_5755)))) (False) (ApplyComparisonOp EQWithNA (ArrayRef (CastToArray (Ref __iruid_5755)) (Ref __iruid_5756) (Str "")) (Ref __iruid_5754)))))))))) (domains (ToArray (StreamMap __iruid_5757 (ToStream False (GetField domains (Ref __iruid_5752))) (Apply concat () String (Apply concat () String (GetField db (Ref __iruid_5757)) (Str ":")) (GetField name (Ref __iruid_5757)))))) (major_consequence (If (ApplyComparisonOp GT (ArrayLen (Ref __iruid_5753)) (I32 0)) (ArrayRef (ToArray (StreamMap __iruid_5758 (ToStream False (ArraySort __iruid_5759 __iruid_5760 (StreamMap __iruid_5761 (ToStream False (GetField consequence_terms (Ref __iruid_5752))) (MakeTuple (0 1) (Let __iruid_5762 (LowerBoundOnOrderedCollection True (Literal Dict[String,Int32] ) (Ref __iruid_5761)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5762) (I32 39)) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5762) (Str ""))) (Ref __iruid_5761)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5762) (Str ""))) (NA Int32)))) (Ref __iruid_5761))) (If (IsNA (GetTupleElement 0 (Ref __iruid_5759))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_5760))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_5759)) (GetTupleElement 0 (Ref __iruid_5760))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_5758)))) (I32 0) (Str " File \"/h...")) (NA String)))))) (ApplyComparisonOp GT (ArrayLen (GetField consequence_terms (Ref __iruid_5751))) (I32 0))) (Let __iruid_5763 (GetField major_consequence (Ref __iruid_5750)) (Let __iruid_5764 (InsertFields (Ref __iruid_5750) None (category (If (ApplyComparisonOp LTEQ (Let __iruid_5765 (LowerBoundOnOrderedCollection True (Literal Dict[String,Int32] ) (Ref __iruid_5763)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5765) (I32 39)) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5765) (Str ""))) (Ref __iruid_5763)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5765) (Str ""))) (NA Int32)))) (I32 4)) (Str "lof") (If (ApplyComparisonOp LTEQ (Let __iruid_5766 (GetField major_consequence (Ref __iruid_5750)) (Let __iruid_5767 (LowerBoundOnOrderedCollection True (Literal Dict[String,Int32] ) (Ref __iruid_5766)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5767) (I32 39)) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5767) (Str ""))) (Ref __iruid_5766)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5767) (Str ""))) (NA Int32))))) (I32 11)) (Str "missense") (If (ApplyComparisonOp LTEQ (Let __iruid_5768 (GetField major_consequence (Ref __iruid_5750)) (Let __iruid_5769 (LowerBoundOnOrderedCollection True (Literal Dict[String,Int32] ) (Ref __iruid_5768)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5769) (I32 39)) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5769) (Str ""))) (Ref __iruid_5768)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5769) (Str ""))) (NA Int32))))) (I32 17)) (Str "synonymous") (Str "other"))))) (hgvs (If (ApplySpecial lor () Boolean (IsNA (GetField hgvsp (Ref __iruid_5750))) (Let __iruid_5770 (ToSet (ToStream False (Literal Array[String] ))) (If (IsNA (Ref __iruid_5770)) (NA Boolean) (Let __iruid_5771 (LowerBoundOnOrderedCollection False (Ref __iruid_5770) (Ref __iruid_5763)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5771) (ArrayLen (CastToArray (Ref __iruid_5770)))) (False) (ApplyComparisonOp EQWithNA (ArrayRef (CastToArray (Ref __iruid_5770)) (Ref __iruid_5771) (Str "")) (Ref __iruid_5763))))))) (Let __iruid_5772 (Apply split () Array[String] (GetField hgvsc (Ref __iruid_5750)) (Str ":")) (ArrayRef (Ref __iruid_5772) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_5772)) (I32 -1)) (Str " File \"/h..."))) (Let __iruid_5773 (GetField hgvsp (Ref __iruid_5750)) (If (ApplySpecial lor () Boolean (Apply contains () Boolean (Ref __iruid_5773) (Str "=")) (Apply contains () Boolean (Ref __iruid_5773) (Str "%3D"))) (Let __iruid_5774 (Apply mkString () String (ToArray (StreamMap __iruid_5775 (ToStream False (Apply split () Array[String] (GetField amino_acids (Ref __iruid_5750)) (Str ""))) (Let __iruid_5776 (LowerBoundOnOrderedCollection True (Literal Dict[String,String] ) (Ref __iruid_5775)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5776) (I32 23)) (NA String) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:String}] ) (Ref __iruid_5776) (Str ""))) (Ref __iruid_5775)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:String}] ) (Ref __iruid_5776) (Str ""))) (NA String)))))) (Str "")) (Apply concat () String (Apply concat () String (Apply concat () String (Str "p.") (Ref __iruid_5774)) (Apply str () String (GetField protein_start (Ref __iruid_5750)))) (Ref __iruid_5774))) (Let __iruid_5777 (Apply split () Array[String] (GetField hgvsp (Ref __iruid_5750)) (Str ":")) (ArrayRef (Ref __iruid_5777) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_5777)) (I32 -1)) (Str " File \"/h..."))))))) (major_consequence_rank (Let __iruid_5778 (LowerBoundOnOrderedCollection True (Literal Dict[String,Int32] ) (Ref __iruid_5763)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5778) (I32 39)) (NA Int32) (If (ApplyComparisonOp EQWithNA (GetField key (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5778) (Str ""))) (Ref __iruid_5763)) (GetField value (ArrayRef (Literal Array[Struct{key:String,value:Int32}] ) (Ref __iruid_5778) (Str ""))) (NA Int32)))))) (MakeTuple (0 1) (Let __iruid_5779 (ApplyComparisonOp EQ (Coalesce (GetField canonical (Ref __iruid_5764)) (I32 0)) (I32 1)) (Let __iruid_5780 (ToSet (ToStream False (GetField consequence_terms (Ref __iruid_5764)))) (Let __iruid_5781 (GetField most_severe_consequence (Ref __iruid_5745)) (Let __iruid_5782 (If (IsNA (Ref __iruid_5780)) (NA Boolean) (Let __iruid_5783 (LowerBoundOnOrderedCollection False (Ref __iruid_5780) (Ref __iruid_5781)) (If (ApplyComparisonOp EQWithNA (Ref __iruid_5783) (ArrayLen (CastToArray (Ref __iruid_5780)))) (False) (ApplyComparisonOp EQWithNA (ArrayRef (CastToArray (Ref __iruid_5780)) (Ref __iruid_5783) (Str "")) (Ref __iruid_5781))))) (If (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_5764)) (Str "")) (Str "protein_co...")) (If (Ref __iruid_5782) (If (Ref __iruid_5779) (I32 1) (I32 2)) (If (Ref __iruid_5779) (I32 3) (I32 4))) (If (Ref __iruid_5782) (If (Ref __iruid_5779) (I32 5) (I32 6)) (If (Ref __iruid_5779) (I32 7) (I32 8)))))))) (Ref __iruid_5764))))) (If (IsNA (GetTupleElement 0 (Ref __iruid_5748))) (False) (If (IsNA (GetTupleElement 0 (Ref __iruid_5749))) (True) (ApplyComparisonOp LT (ApplyComparisonOp Compare (GetTupleElement 0 (Ref __iruid_5748)) (GetTupleElement 0 (Ref __iruid_5749))) (I32 0)))))) (GetTupleElement 1 (Ref __iruid_5747)))) (Let __iruid_5784 (ToArray (StreamMap __iruid_5785 (StreamRange False (I32 0) (ArrayLen (Ref __iruid_5746)) (I32 1)) (Let __iruid_5786 (MakeTuple (0 1) (Ref __iruid_5785) (ArrayRef (Ref __iruid_5746) (If (ApplyComparisonOp LT (Ref __iruid_5785) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_5746)) (Ref __iruid_5785)) (Ref __iruid_5785)) (Str " File \"/h..."))) (InsertFields (GetTupleElement 1 (Ref __iruid_5786)) None (transcript_rank (GetTupleElement 0 (Ref __iruid_5786))))))) (InsertFields (Ref __iruid_5744) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig") (clinvar (MakeStruct (allele_id (GetField ALLELEID (GetField info (GetField __uid_6 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1))))) (clinical_significance (Apply mkString () String (GetField CLNSIG (GetField info (GetField __uid_7 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))) (Str ","))) (gold_stars (GetField gold_stars (GetField __uid_8 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))))) (sortedTranscriptConsequences (Ref __iruid_5784)) (codingGeneIds (ToSet (StreamMap __iruid_5787 (StreamFilter __iruid_5788 (ToStream False (Ref __iruid_5784)) (ApplyComparisonOp EQ (Coalesce (GetField biotype (Ref __iruid_5788)) (Str "")) (Str "protein_co..."))) (GetField gene_id (Ref __iruid_5787))))) (contig (Apply replace () String (Apply contig () String (GetField locus (Ref __iruid_5744))) (Str "^chr") (Str "")))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_6:PCStruct{info:+PCStruct{ALLELEID:PInt32}},__uid_7:PCStruct{info:+PCStruct{CLNSIG:PCArray[PCString]}},__uid_8:PCStruct{gold_stars:PInt32}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 125.276ms, total 16.607s, tagged coverage 89.1 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.058ms, total 16.607s 2022-04-01 03:25:33 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 125.570ms, total 16.607s, tagged coverage 89.0 2022-04-01 03:25:34 root: INFO: encoder cache miss (5 hits, 7 misses, 0.417) 2022-04-01 03:25:34 root: INFO: instruction count: 6: __C859etypeEncode. 2022-04-01 03:25:34 root: INFO: instruction count: 8: __C859etypeEncode.apply 2022-04-01 03:25:34 root: INFO: instruction count: 196: __C859etypeEncode.__m860ENCODE_r_tuple_of_r_dict_of_r_stringANDr_stringANDr_array_of_r_tuple_of_r_stringANDr_stringENDANDr_array_of_r_stringANDr_stringANDr_stringANDr_stringANDr_array_of_r_tuple_of_r_stringANDr_int32ENDANDr_stringANDr_stringANDr_stringANDr_dict_of_r_stringANDr_int32ANDr_stringANDr_stringANDr_array_of_r_stringANDr_stringANDr_stringANDr_stringANDr_stringANDr_stringEND_TO_r_struct_of_r_array_of_r_struct_of_r_binaryANDr_binaryENDANDr_array_of_r_struct_of_r_binaryANDr_binaryENDANDr_array_of_r_binaryANDr_binaryANDr_binaryANDr_binaryANDr_array_of_r_struct_of_r_binaryANDr_int32ENDANDr_binaryANDr_binaryANDr_binaryANDr_array_of_r_struct_of_r_binaryANDr_int32ENDANDr_binaryANDr_binaryANDr_array_of_r_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryEND 2022-04-01 03:25:34 root: INFO: instruction count: 53: __C859etypeEncode.__m861ENCODE_r_array_of_r_tuple_of_r_binaryANDr_binaryEND_TO_r_array_of_r_struct_of_r_binaryANDr_binaryEND 2022-04-01 03:25:34 root: INFO: instruction count: 26: __C859etypeEncode.__m862ENCODE_r_tuple_of_r_binaryANDr_binaryEND_TO_r_struct_of_r_binaryANDr_binaryEND 2022-04-01 03:25:34 root: INFO: instruction count: 19: __C859etypeEncode.__m863ENCODE_r_binary_TO_r_binary 2022-04-01 03:25:34 root: INFO: instruction count: 57: __C859etypeEncode.__m864ENCODE_r_array_of_r_binary_TO_r_array_of_r_binary 2022-04-01 03:25:34 root: INFO: instruction count: 53: __C859etypeEncode.__m865ENCODE_r_array_of_r_tuple_of_r_binaryANDr_int32END_TO_r_array_of_r_struct_of_r_binaryANDr_int32END 2022-04-01 03:25:34 root: INFO: instruction count: 26: __C859etypeEncode.__m866ENCODE_r_tuple_of_r_binaryANDr_int32END_TO_r_struct_of_r_binaryANDr_int32END 2022-04-01 03:25:34 root: INFO: instruction count: 7: __C859etypeEncode.__m867ENCODE_r_int32_TO_r_int32 2022-04-01 03:25:34 MemoryStore: INFO: Block broadcast_15 stored as values in memory (estimated size 3.1 KB, free 5.6 GB) 2022-04-01 03:25:34 MemoryStore: INFO: Block broadcast_15_piece0 stored as bytes in memory (estimated size 1136.0 B, free 5.6 GB) 2022-04-01 03:25:34 BlockManagerInfo: INFO: Added broadcast_15_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 1136.0 B, free: 5.6 GB) 2022-04-01 03:25:34 SparkContext: INFO: Created broadcast 15 from broadcast at SparkBackend.scala:233 2022-04-01 03:25:34 root: INFO: instruction count: 6: __C490Compiled. 2022-04-01 03:25:34 root: INFO: instruction count: 750: __C490Compiled.apply 2022-04-01 03:25:34 root: INFO: instruction count: 11: __C490Compiled.__m496addIRIntermediate 2022-04-01 03:25:34 root: INFO: instruction count: 8: __C490Compiled.__m497addIRIntermediate 2022-04-01 03:25:34 root: INFO: instruction count: 8: __C490Compiled.__m498addIRIntermediate 2022-04-01 03:25:34 root: INFO: instruction count: 8: __C490Compiled.__m499addIRIntermediate 2022-04-01 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__C490Compiled.__m570cord 2022-04-01 03:25:34 root: INFO: instruction count: 135: __C490Compiled.__m571cord 2022-04-01 03:25:34 root: INFO: instruction count: 8: __C490Compiled.__m572addIRIntermediate 2022-04-01 03:25:34 root: INFO: instruction count: 83: __C490Compiled.__m580concat 2022-04-01 03:25:34 root: INFO: instruction count: 83: __C490Compiled.__m583concat 2022-04-01 03:25:34 root: INFO: instruction count: 26: __C490Compiled.__m587cord 2022-04-01 03:25:34 root: INFO: instruction count: 15: __C490Compiled.__m590setup_jab 2022-04-01 03:25:34 root: INFO: instruction count: 81: __C490Compiled.__m608findElt 2022-04-01 03:25:34 root: INFO: instruction count: 11: __C490Compiled.__m615addIRIntermediate 2022-04-01 03:25:34 root: INFO: instruction count: 26: __C490Compiled.__m634cord 2022-04-01 03:25:34 root: INFO: instruction count: 81: __C490Compiled.__m637findElt 2022-04-01 03:25:34 root: INFO: instruction count: 81: __C490Compiled.__m643findElt 2022-04-01 03:25:34 root: INFO: instruction count: 81: __C490Compiled.__m649findElt 2022-04-01 03:25:34 root: INFO: instruction count: 15: __C490Compiled.__m658setup_jab 2022-04-01 03:25:34 root: INFO: instruction count: 50: __C490Compiled.__m659discardNext 2022-04-01 03:25:34 root: INFO: instruction count: 63: __C490Compiled.__m676findElt 2022-04-01 03:25:34 root: INFO: instruction count: 173: __C490Compiled.__m681split 2022-04-01 03:25:34 root: INFO: instruction count: 46: __C490Compiled.__m689contains 2022-04-01 03:25:34 root: INFO: instruction count: 81: __C490Compiled.__m694mkString 2022-04-01 03:25:34 root: INFO: instruction count: 15: __C490Compiled.__m697setup_null 2022-04-01 03:25:34 root: INFO: instruction count: 81: __C490Compiled.__m713findElt 2022-04-01 03:25:34 root: INFO: instruction count: 142: __C490Compiled.__m714cord 2022-04-01 03:25:34 root: INFO: instruction count: 83: __C490Compiled.__m718concat 2022-04-01 03:25:34 root: INFO: instruction count: 61: __C490Compiled.__m722str 2022-04-01 03:25:34 root: INFO: instruction count: 15: __C490Compiled.__m725setup_null 2022-04-01 03:25:34 root: INFO: instruction count: 81: __C490Compiled.__m734findElt 2022-04-01 03:25:34 root: INFO: instruction count: 15: __C490Compiled.__m745setup_jab 2022-04-01 03:25:34 root: INFO: instruction count: 66: __C490Compiled.__m746discardNext 2022-04-01 03:25:34 root: INFO: instruction count: 135: __C490Compiled.__m747cord 2022-04-01 03:25:34 root: INFO: instruction count: 142: __C490Compiled.__m765cord 2022-04-01 03:25:34 root: INFO: instruction count: 92: __C490Compiled.__m766findElt 2022-04-01 03:25:34 root: INFO: instruction count: 38: __C490Compiled.__m767cord 2022-04-01 03:25:34 root: INFO: instruction count: 11: __C490Compiled.__m769addIRIntermediate 2022-04-01 03:25:34 root: INFO: instruction count: 11: __C490Compiled.__m773addIRIntermediate 2022-04-01 03:25:34 root: INFO: instruction count: 26: __C490Compiled.__m803cord 2022-04-01 03:25:34 root: INFO: instruction count: 11: __C490Compiled.__m807addIRIntermediate 2022-04-01 03:25:34 root: INFO: instruction count: 11: __C490Compiled.__m814addIRIntermediate 2022-04-01 03:25:34 root: INFO: instruction count: 8: __C490Compiled.__m815addIRIntermediate 2022-04-01 03:25:34 root: INFO: instruction count: 15: __C490Compiled.__m818setup_jab 2022-04-01 03:25:34 root: INFO: instruction count: 66: __C490Compiled.__m819discardNext 2022-04-01 03:25:34 root: INFO: instruction count: 102: __C490Compiled.__m835replace 2022-04-01 03:25:34 root: INFO: instruction count: 11: __C490Compiled.__m838contig 2022-04-01 03:25:34 root: INFO: instruction count: 8: __C490Compiled.__m843addIRIntermediate 2022-04-01 03:25:34 root: INFO: instruction count: 14: __C490Compiled.setPartitionIndex 2022-04-01 03:25:34 root: INFO: instruction count: 7: __C490Compiled.addPartitionRegion 2022-04-01 03:25:34 root: INFO: instruction count: 25: __C490Compiled.__m847DECODE_r_struct_of_r_array_of_r_struct_of_r_binaryANDr_binaryENDANDr_array_of_r_struct_of_r_binaryANDr_binaryENDANDr_array_of_r_binaryANDr_binaryANDr_binaryANDr_binaryANDr_array_of_r_struct_of_r_binaryANDr_int32ENDANDr_binaryANDr_binaryANDr_binaryANDr_array_of_r_struct_of_r_binaryANDr_int32ENDANDr_binaryANDr_binaryANDr_array_of_r_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryEND_TO_r_tuple_of_r_dict_of_r_stringANDr_stringANDr_array_of_r_tuple_of_r_stringANDr_stringENDANDr_array_of_r_stringANDr_stringANDr_stringANDr_stringANDr_array_of_r_tuple_of_r_stringANDr_int32ENDANDr_stringANDr_stringANDr_stringANDr_dict_of_r_stringANDr_int32ANDr_stringANDr_stringANDr_array_of_r_stringANDr_stringANDr_stringANDr_stringANDr_stringANDr_stringEND 2022-04-01 03:25:34 root: INFO: instruction count: 137: __C490Compiled.__m848read_fields_group_0 2022-04-01 03:25:34 root: INFO: instruction count: 58: __C490Compiled.__m849INPLACE_DECODE_r_array_of_r_struct_of_r_binaryANDr_binaryEND_TO_r_array_of_r_tuple_of_r_binaryANDr_binaryEND 2022-04-01 03:25:34 root: INFO: instruction count: 17: __C490Compiled.__m850INPLACE_DECODE_r_struct_of_r_binaryANDr_binaryEND_TO_r_tuple_of_r_binaryANDr_binaryEND 2022-04-01 03:25:34 root: INFO: instruction count: 18: __C490Compiled.__m851read_fields_group_0 2022-04-01 03:25:34 root: INFO: instruction count: 34: __C490Compiled.__m852INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:34 root: INFO: instruction count: 58: __C490Compiled.__m853INPLACE_DECODE_r_array_of_r_binary_TO_r_array_of_r_binary 2022-04-01 03:25:34 root: INFO: instruction count: 58: __C490Compiled.__m854INPLACE_DECODE_r_array_of_r_struct_of_r_binaryANDr_int32END_TO_r_array_of_r_tuple_of_r_binaryANDr_int32END 2022-04-01 03:25:34 root: INFO: instruction count: 17: __C490Compiled.__m855INPLACE_DECODE_r_struct_of_r_binaryANDr_int32END_TO_r_tuple_of_r_binaryANDr_int32END 2022-04-01 03:25:34 root: INFO: instruction count: 18: __C490Compiled.__m856read_fields_group_0 2022-04-01 03:25:34 root: INFO: instruction count: 11: __C490Compiled.__m857INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:25:34 root: INFO: instruction count: 287: __C490Compiled.addLiterals 2022-04-01 03:25:34 root: INFO: instruction count: 508: __C490Compiled.applyregion270_328 2022-04-01 03:25:34 root: INFO: instruction count: 582: __C490Compiled.applyregion259_362 2022-04-01 03:25:34 root: INFO: instruction count: 307: __C490Compiled.applyregion241_258 2022-04-01 03:25:34 root: INFO: instruction count: 372: __C490Compiled.applyregion437_483 2022-04-01 03:25:34 root: INFO: instruction count: 270: __C490Compiled.applyregion390_433 2022-04-01 03:25:34 root: INFO: instruction count: 138: __C490Compiled.applyregion76_83 2022-04-01 03:25:34 root: INFO: instruction count: 94: __C490Compiled.applyregion236_238 2022-04-01 03:25:34 root: INFO: instruction count: 86: __C490Compiled.applyregion212_219 2022-04-01 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299: __C490Compiled.applyregion601_633 2022-04-01 03:25:34 root: INFO: instruction count: 117: __C490Compiled.applyregion506_513 2022-04-01 03:25:34 root: INFO: instruction count: 87: __C490Compiled.applyregion586_593 2022-04-01 03:25:34 root: INFO: instruction count: 86: __C490Compiled.applyregion578_585 2022-04-01 03:25:34 root: INFO: instruction count: 86: __C490Compiled.applyregion562_569 2022-04-01 03:25:34 root: INFO: instruction count: 86: __C490Compiled.applyregion554_561 2022-04-01 03:25:34 root: INFO: instruction count: 86: __C490Compiled.applyregion546_553 2022-04-01 03:25:34 root: INFO: instruction count: 86: __C490Compiled.applyregion538_545 2022-04-01 03:25:34 root: INFO: instruction count: 86: __C490Compiled.applyregion530_537 2022-04-01 03:25:34 root: INFO: instruction count: 86: __C490Compiled.applyregion522_529 2022-04-01 03:25:34 root: INFO: instruction count: 84: __C490Compiled.applyregion570_577 2022-04-01 03:25:34 root: INFO: instruction count: 82: __C490Compiled.applyregion514_521 2022-04-01 03:25:34 root: INFO: instruction count: 65: __C490Compiled.applyregion767_772 2022-04-01 03:25:34 root: INFO: instruction count: 52: __C490Compiled.applyregion754_759 2022-04-01 03:25:34 root: INFO: instruction count: 58: __C490Compiled.applyregion745_753 2022-04-01 03:25:34 root: INFO: instruction count: 48: __C490Compiled.applyregion961_967 2022-04-01 03:25:34 root: INFO: instruction count: 49: __C490Compiled.applyregion996_1001 2022-04-01 03:25:34 root: INFO: instruction count: 103: __C490Compiled.applyregion1050_1055 2022-04-01 03:25:34 root: INFO: instruction count: 800: __C490Compiled.applyregion505_1026 2022-04-01 03:25:34 root: INFO: instruction count: 632: __C490Compiled.applyregion1035_1124 2022-04-01 03:25:34 root: INFO: instruction count: 577: __C490Compiled.applyregion75_493 2022-04-01 03:25:34 root: INFO: instruction count: 352: __C490Compiled.applyregion1125_1176 2022-04-01 03:25:34 root: INFO: instruction count: 275: __C490Compiled.applyregion1186_1231 2022-04-01 03:25:34 root: INFO: instruction count: 111: __C490Compiled.applyregion66_74 2022-04-01 03:25:34 root: INFO: instruction count: 98: __C490Compiled.applyregion1177_1185 2022-04-01 03:25:34 root: INFO: instruction count: 116: __C490Compiled.applyregion1460_1467 2022-04-01 03:25:34 root: INFO: instruction count: 86: __C490Compiled.applyregion1548_1555 2022-04-01 03:25:34 root: INFO: instruction count: 86: __C490Compiled.applyregion1540_1547 2022-04-01 03:25:34 root: INFO: instruction count: 86: __C490Compiled.applyregion1532_1539 2022-04-01 03:25:34 root: INFO: instruction count: 86: __C490Compiled.applyregion1516_1523 2022-04-01 03:25:34 root: INFO: instruction count: 86: __C490Compiled.applyregion1508_1515 2022-04-01 03:25:34 root: INFO: instruction count: 86: __C490Compiled.applyregion1500_1507 2022-04-01 03:25:34 root: INFO: instruction count: 531: __C490Compiled.applyregion1459_1561 2022-04-01 03:25:34 root: INFO: instruction count: 716: __C490Compiled.applyregion32_1238 2022-04-01 03:25:34 root: INFO: instruction count: 304: __C490Compiled.applyregion1316_1365 2022-04-01 03:25:34 root: INFO: instruction count: 212: __C490Compiled.applyregion1258_1265 2022-04-01 03:25:34 root: INFO: instruction count: 205: __C490Compiled.applyregion1373_1380 2022-04-01 03:25:34 root: INFO: instruction count: 188: __C490Compiled.applyregion0_7 2022-04-01 03:25:34 root: INFO: instruction count: 124: __C490Compiled.applyregion1253_1255 2022-04-01 03:25:34 root: INFO: instruction count: 126: __C490Compiled.applyregion1291_1300 2022-04-01 03:25:34 root: INFO: instruction count: 128: __C490Compiled.applyregion1421_1429 2022-04-01 03:25:34 root: INFO: instruction count: 123: __C490Compiled.applyregion1282_1290 2022-04-01 03:25:34 root: INFO: instruction count: 114: __C490Compiled.applyregion1240_1252 2022-04-01 03:25:34 root: INFO: instruction count: 102: __C490Compiled.applyregion1389_1396 2022-04-01 03:25:34 root: INFO: instruction count: 102: __C490Compiled.applyregion1274_1281 2022-04-01 03:25:34 root: INFO: instruction count: 102: __C490Compiled.applyregion16_23 2022-04-01 03:25:34 root: INFO: instruction count: 98: __C490Compiled.applyregion1381_1388 2022-04-01 03:25:34 root: INFO: instruction count: 98: __C490Compiled.applyregion1266_1273 2022-04-01 03:25:34 root: INFO: instruction count: 98: __C490Compiled.applyregion8_15 2022-04-01 03:25:34 root: INFO: instruction count: 98: __C490Compiled.applyregion1397_1404 2022-04-01 03:25:34 root: INFO: instruction count: 87: __C490Compiled.applyregion1366_1368 2022-04-01 03:25:34 root: INFO: instruction count: 98: __C490Compiled.applyregion1405_1411 2022-04-01 03:25:34 root: INFO: instruction count: 6: __C868applySpills. 2022-04-01 03:25:34 root: INFO: instruction count: 6: __C512sort_compare. 2022-04-01 03:25:34 root: INFO: instruction count: 10: __C512sort_compare.apply 2022-04-01 03:25:34 root: INFO: instruction count: 21: __C512sort_compare.apply 2022-04-01 03:25:34 root: INFO: instruction count: 203: __C512sort_compare.__m514sort 2022-04-01 03:25:34 root: INFO: instruction count: 26: __C512sort_compare.__m515cord 2022-04-01 03:25:34 root: INFO: instruction count: 49: __C512sort_compare.__m516cord 2022-04-01 03:25:34 root: INFO: instruction count: 6: __C551sort_compare. 2022-04-01 03:25:34 root: INFO: instruction count: 10: __C551sort_compare.apply 2022-04-01 03:25:34 root: INFO: instruction count: 21: __C551sort_compare.apply 2022-04-01 03:25:34 root: INFO: instruction count: 45: __C551sort_compare.__m553sort 2022-04-01 03:25:34 root: INFO: instruction count: 26: __C551sort_compare.__m554cord 2022-04-01 03:25:34 root: INFO: instruction count: 142: __C551sort_compare.__m555cord 2022-04-01 03:25:34 root: INFO: instruction count: 6: __C591sort_compare. 2022-04-01 03:25:34 root: INFO: instruction count: 10: __C591sort_compare.apply 2022-04-01 03:25:34 root: INFO: instruction count: 21: __C591sort_compare.apply 2022-04-01 03:25:34 root: INFO: instruction count: 203: __C591sort_compare.__m593sort 2022-04-01 03:25:34 root: INFO: instruction count: 26: __C591sort_compare.__m594cord 2022-04-01 03:25:34 root: INFO: instruction count: 49: __C591sort_compare.__m595cord 2022-04-01 03:25:34 root: INFO: instruction count: 6: __C660sort_compare. 2022-04-01 03:25:34 root: INFO: instruction count: 10: __C660sort_compare.apply 2022-04-01 03:25:34 root: INFO: instruction count: 21: __C660sort_compare.apply 2022-04-01 03:25:34 root: INFO: instruction count: 45: __C660sort_compare.__m662sort 2022-04-01 03:25:34 root: INFO: instruction count: 26: __C660sort_compare.__m663cord 2022-04-01 03:25:34 root: INFO: instruction count: 142: __C660sort_compare.__m664cord 2022-04-01 03:25:34 root: INFO: instruction count: 6: __C748sort_compare. 2022-04-01 03:25:34 root: INFO: instruction count: 20: __C748sort_compare.apply 2022-04-01 03:25:34 root: INFO: instruction count: 21: __C748sort_compare.apply 2022-04-01 03:25:34 root: INFO: instruction count: 61: __C748sort_compare.__m750sort 2022-04-01 03:25:34 root: INFO: instruction count: 26: __C748sort_compare.__m751cord 2022-04-01 03:25:34 root: INFO: instruction count: 142: __C748sort_compare.__m752cord 2022-04-01 03:25:34 root: INFO: instruction count: 6: __C820sort_compare. 2022-04-01 03:25:34 root: INFO: instruction count: 20: __C820sort_compare.apply 2022-04-01 03:25:34 root: INFO: instruction count: 21: __C820sort_compare.apply 2022-04-01 03:25:34 root: INFO: instruction count: 61: __C820sort_compare.__m822sort 2022-04-01 03:25:34 root: INFO: instruction count: 26: __C820sort_compare.__m823cord 2022-04-01 03:25:34 root: INFO: instruction count: 142: __C820sort_compare.__m824cord 2022-04-01 03:25:34 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:35 root: INFO: decoder cache hit 2022-04-01 03:25:35 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/parts/part-0' for reading 2022-04-01 03:25:35 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:36 root: INFO: decoder cache miss (3 hits, 11 misses, 0.214 2022-04-01 03:25:36 root: INFO: instruction count: 6: __C1024etypeDecode. 2022-04-01 03:25:36 root: INFO: instruction count: 8: __C1024etypeDecode.apply 2022-04-01 03:25:36 root: INFO: instruction count: 47: __C1024etypeDecode.__m1025DECODE_r_struct_of_o_struct_of_r_binaryANDr_int32ENDANDo_array_of_o_binaryANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_struct_of_o_binaryENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryENDANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_int32ENDANDo_float32ANDo_float64END_TO_r_tuple_of_o_locusANDo_array_of_o_stringANDo_tuple_of_o_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDEND 2022-04-01 03:25:36 root: INFO: instruction count: 283: __C1024etypeDecode.__m1026read_fields_group_0 2022-04-01 03:25:36 root: INFO: instruction count: 17: __C1024etypeDecode.__m1027INPLACE_DECODE_o_struct_of_r_binaryANDr_int32END_TO_o_tuple_of_r_binaryANDr_int32END 2022-04-01 03:25:36 root: INFO: instruction count: 18: __C1024etypeDecode.__m1028read_fields_group_0 2022-04-01 03:25:36 root: INFO: instruction count: 34: __C1024etypeDecode.__m1029INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:36 root: INFO: instruction count: 11: __C1024etypeDecode.__m1030INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:25:36 root: INFO: instruction count: 105: __C1024etypeDecode.__m1031INPLACE_DECODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:25:36 root: INFO: instruction count: 34: __C1024etypeDecode.__m1032INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:25:36 root: INFO: instruction count: 84: __C1024etypeDecode.__m1033SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64END 2022-04-01 03:25:36 root: INFO: instruction count: 6: __C1024etypeDecode.__m1034SKIP_o_int32 2022-04-01 03:25:36 root: INFO: instruction count: 6: __C1024etypeDecode.__m1035SKIP_o_float64 2022-04-01 03:25:36 root: INFO: instruction count: 39: __C1024etypeDecode.__m1036SKIP_o_struct_of_o_binaryEND 2022-04-01 03:25:36 root: INFO: instruction count: 10: __C1024etypeDecode.__m1037SKIP_o_binary 2022-04-01 03:25:36 root: INFO: instruction count: 39: __C1024etypeDecode.__m1038SKIP_o_struct_of_o_float32END 2022-04-01 03:25:36 root: INFO: instruction count: 6: __C1024etypeDecode.__m1039SKIP_o_float32 2022-04-01 03:25:36 root: INFO: instruction count: 39: __C1024etypeDecode.__m1040SKIP_o_struct_of_o_float64END 2022-04-01 03:25:36 root: INFO: instruction count: 30: __C1024etypeDecode.__m1041INPLACE_DECODE_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND_TO_o_tuple_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:25:36 root: INFO: instruction count: 228: __C1024etypeDecode.__m1042read_fields_group_0 2022-04-01 03:25:36 root: INFO: instruction count: 99: __C1024etypeDecode.__m1043SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:25:36 root: INFO: instruction count: 39: __C1024etypeDecode.__m1044SKIP_o_struct_of_o_float64END 2022-04-01 03:25:36 root: INFO: instruction count: 39: __C1024etypeDecode.__m1045SKIP_o_struct_of_o_float32END 2022-04-01 03:25:36 root: INFO: instruction count: 129: __C1024etypeDecode.__m1046SKIP_o_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:25:36 root: INFO: instruction count: 129: __C1024etypeDecode.__m1047SKIP_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:25:36 root: INFO: instruction count: 39: __C1024etypeDecode.__m1048SKIP_o_struct_of_o_int32END 2022-04-01 03:25:39 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:40 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:40 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:40 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:40 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:41 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:41 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:41 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:41 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:42 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.049ms, total 24.783s 2022-04-01 03:25:42 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 56: (Coalesce (InsertFields (Let __iruid_4322 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)) (Let __iruid_4323 (GetField locus (Ref __iruid_4322)) (Let __iruid_4324 (GetField alleles (Ref __iruid_4322)) (InsertFields (Ref __iruid_4322) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains") (dbnsfp (GetField dbnsfp (GetField __uid_31 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)))) (docId (ApplyIR slice () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_4323)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_4323)))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_4324) (I32 0) (Str " File \"/h..."))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_4324) (I32 1) (Str " File \"/h..."))) (I32 0) (I32 512))) (domains (ToSet (StreamFlatMap __iruid_4325 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_4322))) (ToStream False (GetField domains (Ref __iruid_4325)))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.566ms, total 24.786s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.167ms, total 24.786s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.823ms, total 24.787s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 1.278ms, total 24.788s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.162ms, total 24.789s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 3.309ms, total 24.792s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.289ms, total 24.792s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.212ms, total 24.793s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.768ms, total 24.793s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 1.007ms, total 24.794s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.253ms, total 24.795s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 3.365ms, total 24.798s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.323ms, total 24.799s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.163ms, total 24.799s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.764ms, total 24.800s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 1.010ms, total 24.801s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.155ms, total 24.801s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 3.003ms, total 24.804s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 18.654ms, total 24.804s, tagged coverage 94.4 2022-04-01 03:25:42 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 56: (Coalesce (InsertFields (Let __iruid_5906 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)) (Let __iruid_5907 (GetField locus (Ref __iruid_5906)) (Let __iruid_5908 (GetField alleles (Ref __iruid_5906)) (InsertFields (Ref __iruid_5906) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains") (dbnsfp (GetField dbnsfp (GetField __uid_31 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)))) (docId (ApplyIR slice () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_5907)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_5907)))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_5908) (I32 0) (Str " File \"/h..."))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_5908) (I32 1) (Str " File \"/h..."))) (I32 0) (I32 512))) (domains (ToSet (StreamFlatMap __iruid_5909 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_5906))) (ToStream False (GetField domains (Ref __iruid_5909)))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 22.928ms, total 24.806s, tagged coverage 76.8 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.012ms, total 24.806s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 23.226ms, total 24.806s, tagged coverage 76.1 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.029ms, total 24.807s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.626ms, total 24.807s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.059ms, total 24.807s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.842ms, total 24.807s, tagged coverage 84.8 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.017ms, total 24.808s 2022-04-01 03:25:42 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 138: (Coalesce (InsertFields (Let __iruid_5906 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)) (Let __iruid_5907 (GetField locus (Ref __iruid_5906)) (Let __iruid_5908 (GetField alleles (Ref __iruid_5906)) (InsertFields (Ref __iruid_5906) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains") (dbnsfp (GetField dbnsfp (GetField __uid_31 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)))) (docId (Let __iruid_5934 (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_5907)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_5907)))) (Str "-")) (Let __iruid_5923 (Ref __iruid_5908) (Let __iruid_5924 (I32 0) (Let __iruid_5925 (Str " File \"/h...") (ArrayRef (Ref __iruid_5923) (If (ApplyComparisonOp LT (Ref __iruid_5924) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_5923)) (Ref __iruid_5924)) (Ref __iruid_5924)) (Ref __iruid_5925)))))) (Str "-")) (Let __iruid_5926 (Ref __iruid_5908) (Let __iruid_5927 (I32 1) (Let __iruid_5928 (Str " File \"/h...") (ArrayRef (Ref __iruid_5926) (If (ApplyComparisonOp LT (Ref __iruid_5927) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_5926)) (Ref __iruid_5927)) (Ref __iruid_5927)) (Ref __iruid_5928)))))) (Let __iruid_5935 (I32 0) (Let __iruid_5936 (I32 512) (Let __iruid_5937 (Apply length () Int32 (Ref __iruid_5934)) (Let __iruid_5938 (If (ApplyComparisonOp LT (Ref __iruid_5935) (ApplyUnaryPrimOp Negate (Ref __iruid_5937))) (I32 0) (If (ApplyComparisonOp LT (Ref __iruid_5935) (I32 0)) (ApplyBinaryPrimOp Add (Ref __iruid_5935) (Ref __iruid_5937)) (If (ApplyComparisonOp GTEQ (Ref __iruid_5935) (Ref __iruid_5937)) (Ref __iruid_5937) (Ref __iruid_5935)))) (Let __iruid_5939 (If (ApplyComparisonOp LT (Ref __iruid_5936) (ApplyUnaryPrimOp Negate (Ref __iruid_5937))) (I32 0) (If (ApplyComparisonOp LT (Ref __iruid_5936) (I32 0)) (ApplyBinaryPrimOp Add (Ref __iruid_5936) (Ref __iruid_5937)) (If (ApplyComparisonOp GTEQ (Ref __iruid_5936) (Ref __iruid_5937)) (Ref __iruid_5937) (Ref __iruid_5936)))) (Apply substring () String (Ref __iruid_5934) (Ref __iruid_5938) (If (ApplyComparisonOp LT (Ref __iruid_5939) (Ref __iruid_5938)) (Ref __iruid_5938) (Ref __iruid_5939)))))))))) (domains (ToSet (StreamFlatMap __iruid_5909 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_5906))) (ToStream False (GetField domains (Ref __iruid_5909)))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.366ms, total 24.811s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.289ms, total 24.811s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.678ms, total 24.812s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 2.414ms, total 24.814s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.387ms, total 24.815s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 4.321ms, total 24.819s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 1.008ms, total 24.820s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.243ms, total 24.821s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.671ms, total 24.821s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 11.054ms, total 24.832s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.260ms, total 24.833s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 3.450ms, total 24.836s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.292ms, total 24.837s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.215ms, total 24.837s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.452ms, total 24.837s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 1.703ms, total 24.839s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.236ms, total 24.839s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 3.216ms, total 24.843s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 32.228ms, total 24.843s, tagged coverage 97.0 2022-04-01 03:25:42 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 92: (Coalesce (InsertFields (Let __iruid_5964 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)) (Let __iruid_5965 (GetField locus (Ref __iruid_5964)) (Let __iruid_5966 (GetField alleles (Ref __iruid_5964)) (InsertFields (Ref __iruid_5964) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains") (dbnsfp (GetField dbnsfp (GetField __uid_31 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)))) (docId (Let __iruid_5967 (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_5965)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_5965)))) (Str "-")) (ArrayRef (Ref __iruid_5966) (I32 0) (Str " File \"/h..."))) (Str "-")) (ArrayRef (Ref __iruid_5966) (I32 1) (Str " File \"/h..."))) (Let __iruid_5968 (Apply length () Int32 (Ref __iruid_5967)) (Let __iruid_5969 (If (ApplyComparisonOp LT (I32 0) (ApplyUnaryPrimOp Negate (Ref __iruid_5968))) (I32 0) (If (ApplyComparisonOp GTEQ (I32 0) (Ref __iruid_5968)) (Ref __iruid_5968) (I32 0))) (Let __iruid_5970 (If (ApplyComparisonOp LT (I32 512) (ApplyUnaryPrimOp Negate (Ref __iruid_5968))) (I32 0) (If (ApplyComparisonOp GTEQ (I32 512) (Ref __iruid_5968)) (Ref __iruid_5968) (I32 512))) (Apply substring () String (Ref __iruid_5967) (Ref __iruid_5969) (If (ApplyComparisonOp LT (Ref __iruid_5970) (Ref __iruid_5969)) (Ref __iruid_5969) (Ref __iruid_5970)))))))) (domains (ToSet (StreamFlatMap __iruid_5971 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_5964))) (ToStream False (GetField domains (Ref __iruid_5971)))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 36.855ms, total 24.845s, tagged coverage 84.8 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.054ms, total 24.845s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 37.074ms, total 24.845s, tagged coverage 84.5 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.035ms, total 24.846s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 11.811ms, total 24.858s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.034ms, total 24.858s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 12.053ms, total 24.858s, tagged coverage 98.6 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.011ms, total 24.859s 2022-04-01 03:25:42 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 92: (Coalesce (InsertFields (Let __iruid_5964 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)) (Let __iruid_5965 (GetField locus (Ref __iruid_5964)) (Let __iruid_5966 (GetField alleles (Ref __iruid_5964)) (InsertFields (Ref __iruid_5964) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains") (dbnsfp (GetField dbnsfp (GetField __uid_31 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)))) (docId (Let __iruid_5967 (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_5965)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_5965)))) (Str "-")) (ArrayRef (Ref __iruid_5966) (I32 0) (Str " File \"/h..."))) (Str "-")) (ArrayRef (Ref __iruid_5966) (I32 1) (Str " File \"/h..."))) (Let __iruid_5968 (Apply length () Int32 (Ref __iruid_5967)) (Let __iruid_5969 (If (ApplyComparisonOp LT (I32 0) (ApplyUnaryPrimOp Negate (Ref __iruid_5968))) (I32 0) (If (ApplyComparisonOp GTEQ (I32 0) (Ref __iruid_5968)) (Ref __iruid_5968) (I32 0))) (Let __iruid_5970 (If (ApplyComparisonOp LT (I32 512) (ApplyUnaryPrimOp Negate (Ref __iruid_5968))) (I32 0) (If (ApplyComparisonOp GTEQ (I32 512) (Ref __iruid_5968)) (Ref __iruid_5968) (I32 512))) (Apply substring () String (Ref __iruid_5967) (Ref __iruid_5969) (If (ApplyComparisonOp LT (Ref __iruid_5970) (Ref __iruid_5969)) (Ref __iruid_5969) (Ref __iruid_5970)))))))) (domains (ToSet (StreamFlatMap __iruid_5971 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_5964))) (ToStream False (GetField domains (Ref __iruid_5971)))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.317ms, total 24.861s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.221ms, total 24.861s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.448ms, total 24.862s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 1.560ms, total 24.864s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.201ms, total 24.864s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 3.066ms, total 24.867s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.349ms, total 24.867s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.238ms, total 24.868s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.433ms, total 24.868s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 1.543ms, total 24.870s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.259ms, total 24.870s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 3.286ms, total 24.873s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.787ms, total 24.874s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.213ms, total 24.874s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.430ms, total 24.875s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 1.544ms, total 24.877s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.212ms, total 24.877s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.964ms, total 24.880s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 19.060ms, total 24.880s, tagged coverage 94.8 2022-04-01 03:25:42 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 92: (Coalesce (InsertFields (Let __iruid_5988 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)) (Let __iruid_5989 (GetField locus (Ref __iruid_5988)) (Let __iruid_5990 (GetField alleles (Ref __iruid_5988)) (InsertFields (Ref __iruid_5988) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains") (dbnsfp (GetField dbnsfp (GetField __uid_31 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)))) (docId (Let __iruid_5991 (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_5989)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_5989)))) (Str "-")) (ArrayRef (Ref __iruid_5990) (I32 0) (Str " File \"/h..."))) (Str "-")) (ArrayRef (Ref __iruid_5990) (I32 1) (Str " File \"/h..."))) (Let __iruid_5992 (Apply length () Int32 (Ref __iruid_5991)) (Let __iruid_5993 (If (ApplyComparisonOp LT (I32 0) (ApplyUnaryPrimOp Negate (Ref __iruid_5992))) (I32 0) (If (ApplyComparisonOp GTEQ (I32 0) (Ref __iruid_5992)) (Ref __iruid_5992) (I32 0))) (Let __iruid_5994 (If (ApplyComparisonOp LT (I32 512) (ApplyUnaryPrimOp Negate (Ref __iruid_5992))) (I32 0) (If (ApplyComparisonOp GTEQ (I32 512) (Ref __iruid_5992)) (Ref __iruid_5992) (I32 512))) (Apply substring () String (Ref __iruid_5991) (Ref __iruid_5993) (If (ApplyComparisonOp LT (Ref __iruid_5994) (Ref __iruid_5993)) (Ref __iruid_5993) (Ref __iruid_5994)))))))) (domains (ToSet (StreamFlatMap __iruid_5995 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_5988))) (ToStream False (GetField domains (Ref __iruid_5995)))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_31:PCStruct{dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 23.015ms, total 24.882s, tagged coverage 78.5 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.016ms, total 24.882s 2022-04-01 03:25:42 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 23.187ms, total 24.882s, tagged coverage 78.1 2022-04-01 03:25:42 root: INFO: encoder cache miss (5 hits, 8 misses, 0.385) 2022-04-01 03:25:42 root: INFO: instruction count: 6: __C1141etypeEncode. 2022-04-01 03:25:42 root: INFO: instruction count: 8: __C1141etypeEncode.apply 2022-04-01 03:25:42 root: INFO: instruction count: 46: __C1141etypeEncode.__m1142ENCODE_r_tuple_of_r_stringANDr_stringANDr_stringANDr_stringEND_TO_r_struct_of_r_binaryANDr_binaryANDr_binaryANDr_binaryEND 2022-04-01 03:25:42 root: INFO: instruction count: 19: __C1141etypeEncode.__m1143ENCODE_r_binary_TO_r_binary 2022-04-01 03:25:42 MemoryStore: INFO: Block broadcast_16 stored as values in memory (estimated size 128.0 B, free 5.6 GB) 2022-04-01 03:25:42 MemoryStore: INFO: Block broadcast_16_piece0 stored as bytes in memory (estimated size 126.0 B, free 5.6 GB) 2022-04-01 03:25:42 BlockManagerInfo: INFO: Added broadcast_16_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 126.0 B, free: 5.6 GB) 2022-04-01 03:25:42 SparkContext: INFO: Created broadcast 16 from broadcast at SparkBackend.scala:233 2022-04-01 03:25:42 root: INFO: instruction count: 6: __C1049Compiled. 2022-04-01 03:25:42 root: INFO: instruction count: 496: __C1049Compiled.apply 2022-04-01 03:25:42 root: INFO: instruction count: 11: __C1049Compiled.__m1055addIRIntermediate 2022-04-01 03:25:42 root: INFO: instruction count: 8: __C1049Compiled.__m1056addIRIntermediate 2022-04-01 03:25:42 root: INFO: instruction count: 8: __C1049Compiled.__m1057addIRIntermediate 2022-04-01 03:25:42 root: INFO: instruction count: 8: __C1049Compiled.__m1058addIRIntermediate 2022-04-01 03:25:42 root: INFO: instruction count: 11: __C1049Compiled.__m1059addIRIntermediate 2022-04-01 03:25:42 root: INFO: instruction count: 8: __C1049Compiled.__m1060addIRIntermediate 2022-04-01 03:25:42 root: INFO: instruction count: 11: __C1049Compiled.__m1061addIRIntermediate 2022-04-01 03:25:42 root: INFO: instruction count: 11: __C1049Compiled.__m1062addIRIntermediate 2022-04-01 03:25:42 root: INFO: instruction count: 8: __C1049Compiled.__m1063addIRIntermediate 2022-04-01 03:25:42 root: INFO: instruction count: 8: __C1049Compiled.__m1064addIRIntermediate 2022-04-01 03:25:42 root: INFO: instruction count: 11: __C1049Compiled.__m1076addIRIntermediate 2022-04-01 03:25:42 root: INFO: instruction count: 83: __C1049Compiled.__m1079concat 2022-04-01 03:25:42 root: INFO: instruction count: 102: __C1049Compiled.__m1082replace 2022-04-01 03:25:42 root: INFO: instruction count: 11: __C1049Compiled.__m1085contig 2022-04-01 03:25:42 root: INFO: instruction count: 61: __C1049Compiled.__m1089str 2022-04-01 03:25:42 root: INFO: instruction count: 15: __C1049Compiled.__m1092setup_null 2022-04-01 03:25:42 root: INFO: instruction count: 11: __C1049Compiled.__m1095position 2022-04-01 03:25:42 root: INFO: instruction count: 26: __C1049Compiled.__m1098length 2022-04-01 03:25:42 root: INFO: instruction count: 26: __C1049Compiled.__m1101cord 2022-04-01 03:25:42 root: INFO: instruction count: 26: __C1049Compiled.__m1102cord 2022-04-01 03:25:42 root: INFO: instruction count: 65: __C1049Compiled.__m1105substring 2022-04-01 03:25:42 root: INFO: instruction count: 15: __C1049Compiled.__m1110setup_jab 2022-04-01 03:25:42 root: INFO: instruction count: 66: __C1049Compiled.__m1111discardNext 2022-04-01 03:25:42 root: INFO: instruction count: 135: __C1049Compiled.__m1112cord 2022-04-01 03:25:42 root: INFO: instruction count: 8: __C1049Compiled.__m1133addIRIntermediate 2022-04-01 03:25:42 root: INFO: instruction count: 14: __C1049Compiled.setPartitionIndex 2022-04-01 03:25:42 root: INFO: instruction count: 7: __C1049Compiled.addPartitionRegion 2022-04-01 03:25:42 root: INFO: instruction count: 25: __C1049Compiled.__m1137DECODE_r_struct_of_r_binaryANDr_binaryANDr_binaryANDr_binaryEND_TO_r_tuple_of_r_stringANDr_stringANDr_stringANDr_stringEND 2022-04-01 03:25:42 root: INFO: instruction count: 32: __C1049Compiled.__m1138read_fields_group_0 2022-04-01 03:25:42 root: INFO: instruction count: 34: __C1049Compiled.__m1139INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:42 root: INFO: instruction count: 68: __C1049Compiled.addLiterals 2022-04-01 03:25:42 root: INFO: instruction count: 302: __C1049Compiled.applyregion138_186 2022-04-01 03:25:42 root: INFO: instruction count: 167: __C1049Compiled.applyregion194_201 2022-04-01 03:25:42 root: INFO: instruction count: 122: __C1049Compiled.applyregion226_233 2022-04-01 03:25:42 root: INFO: instruction count: 102: __C1049Compiled.applyregion210_217 2022-04-01 03:25:42 root: INFO: instruction count: 98: __C1049Compiled.applyregion202_209 2022-04-01 03:25:42 root: INFO: instruction count: 98: __C1049Compiled.applyregion218_225 2022-04-01 03:25:42 root: INFO: instruction count: 719: __C1049Compiled.applyregion106_257 2022-04-01 03:25:42 root: INFO: instruction count: 486: __C1049Compiled.applyregion72_259 2022-04-01 03:25:42 root: INFO: instruction count: 243: __C1049Compiled.applyregion32_39 2022-04-01 03:25:42 root: INFO: instruction count: 188: __C1049Compiled.applyregion0_7 2022-04-01 03:25:42 root: INFO: instruction count: 136: __C1049Compiled.applyregion40_47 2022-04-01 03:25:42 root: INFO: instruction count: 110: __C1049Compiled.applyregion64_71 2022-04-01 03:25:42 root: INFO: instruction count: 6: __C1144applySpills. 2022-04-01 03:25:42 root: INFO: instruction count: 6: __C1113sort_compare. 2022-04-01 03:25:42 root: INFO: instruction count: 20: __C1113sort_compare.apply 2022-04-01 03:25:42 root: INFO: instruction count: 21: __C1113sort_compare.apply 2022-04-01 03:25:42 root: INFO: instruction count: 61: __C1113sort_compare.__m1115sort 2022-04-01 03:25:42 root: INFO: instruction count: 26: __C1113sort_compare.__m1116cord 2022-04-01 03:25:42 root: INFO: instruction count: 142: __C1113sort_compare.__m1117cord 2022-04-01 03:25:42 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:42 root: INFO: decoder cache hit 2022-04-01 03:25:42 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/parts/part-0' for reading 2022-04-01 03:25:42 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:43 root: INFO: decoder cache miss (4 hits, 12 misses, 0.250 2022-04-01 03:25:43 root: INFO: instruction count: 6: __C1175etypeDecode. 2022-04-01 03:25:43 root: INFO: instruction count: 8: __C1175etypeDecode.apply 2022-04-01 03:25:43 root: INFO: instruction count: 47: __C1175etypeDecode.__m1176DECODE_r_struct_of_o_struct_of_r_binaryANDr_int32ENDANDo_array_of_o_binaryANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_struct_of_o_binaryENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryENDANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_int32ENDANDo_float32ANDo_float64END_TO_r_tuple_of_o_locusANDo_array_of_o_stringANDo_tuple_of_o_float64ENDEND 2022-04-01 03:25:43 root: INFO: instruction count: 283: __C1175etypeDecode.__m1177read_fields_group_0 2022-04-01 03:25:43 root: INFO: instruction count: 17: __C1175etypeDecode.__m1178INPLACE_DECODE_o_struct_of_r_binaryANDr_int32END_TO_o_tuple_of_r_binaryANDr_int32END 2022-04-01 03:25:43 root: INFO: instruction count: 18: __C1175etypeDecode.__m1179read_fields_group_0 2022-04-01 03:25:43 root: INFO: instruction count: 34: __C1175etypeDecode.__m1180INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:43 root: INFO: instruction count: 11: __C1175etypeDecode.__m1181INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:25:43 root: INFO: instruction count: 105: __C1175etypeDecode.__m1182INPLACE_DECODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:25:43 root: INFO: instruction count: 34: __C1175etypeDecode.__m1183INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:25:43 root: INFO: instruction count: 84: __C1175etypeDecode.__m1184SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64END 2022-04-01 03:25:43 root: INFO: instruction count: 6: __C1175etypeDecode.__m1185SKIP_o_int32 2022-04-01 03:25:43 root: INFO: instruction count: 6: __C1175etypeDecode.__m1186SKIP_o_float64 2022-04-01 03:25:43 root: INFO: instruction count: 39: __C1175etypeDecode.__m1187SKIP_o_struct_of_o_binaryEND 2022-04-01 03:25:43 root: INFO: instruction count: 10: __C1175etypeDecode.__m1188SKIP_o_binary 2022-04-01 03:25:43 root: INFO: instruction count: 39: __C1175etypeDecode.__m1189SKIP_o_struct_of_o_float32END 2022-04-01 03:25:43 root: INFO: instruction count: 6: __C1175etypeDecode.__m1190SKIP_o_float32 2022-04-01 03:25:43 root: INFO: instruction count: 30: __C1175etypeDecode.__m1191INPLACE_DECODE_o_struct_of_o_float64END_TO_o_tuple_of_o_float64END 2022-04-01 03:25:43 root: INFO: instruction count: 32: __C1175etypeDecode.__m1192read_fields_group_0 2022-04-01 03:25:43 root: INFO: instruction count: 11: __C1175etypeDecode.__m1193INPLACE_DECODE_o_float64_TO_o_float64 2022-04-01 03:25:43 root: INFO: instruction count: 144: __C1175etypeDecode.__m1194SKIP_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:25:43 root: INFO: instruction count: 99: __C1175etypeDecode.__m1195SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:25:43 root: INFO: instruction count: 39: __C1175etypeDecode.__m1196SKIP_o_struct_of_o_float64END 2022-04-01 03:25:43 root: INFO: instruction count: 39: __C1175etypeDecode.__m1197SKIP_o_struct_of_o_float32END 2022-04-01 03:25:43 root: INFO: instruction count: 129: __C1175etypeDecode.__m1198SKIP_o_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:25:43 root: INFO: instruction count: 129: __C1175etypeDecode.__m1199SKIP_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:25:43 root: INFO: instruction count: 39: __C1175etypeDecode.__m1200SKIP_o_struct_of_o_int32END 2022-04-01 03:25:46 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:47 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:47 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:50 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:50 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:50 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:51 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:51 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:51 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:52 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:52 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:52 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.021ms, total 34.891s 2022-04-01 03:25:52 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 26: (Coalesce (InsertFields (Let __iruid_4338 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)) (InsertFields (Ref __iruid_4338) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end") (eigen (GetField eigen (GetField __uid_34 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)))) (end (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (Apply position () Int32 (GetField locus (Ref __iruid_4338))) (Apply length () Int32 (ApplyIR indexArray () String (GetField alleles (Ref __iruid_4338)) (I32 0) (Str " File \"/h...")))) (I32 1))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.347ms, total 34.893s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.096ms, total 34.893s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.256ms, total 34.893s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.565ms, total 34.894s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.095ms, total 34.894s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.119ms, total 34.896s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.139ms, total 34.897s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.090ms, total 34.897s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.221ms, total 34.897s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.460ms, total 34.897s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.084ms, total 34.898s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.251ms, total 34.900s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.205ms, total 34.900s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.087ms, total 34.900s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.233ms, total 34.901s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.460ms, total 34.901s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.085ms, total 34.901s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.981ms, total 34.903s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 10.694ms, total 34.903s, tagged coverage 91.4 2022-04-01 03:25:52 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 26: (Coalesce (InsertFields (Let __iruid_6026 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)) (InsertFields (Ref __iruid_6026) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end") (eigen (GetField eigen (GetField __uid_34 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)))) (end (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (Apply position () Int32 (GetField locus (Ref __iruid_6026))) (Apply length () Int32 (ApplyIR indexArray () String (GetField alleles (Ref __iruid_6026)) (I32 0) (Str " File \"/h...")))) (I32 1))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 13.696ms, total 34.905s, tagged coverage 71.4 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.010ms, total 34.905s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 13.938ms, total 34.905s, tagged coverage 70.3 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.016ms, total 34.905s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.185ms, total 34.906s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.028ms, total 34.906s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.357ms, total 34.906s, tagged coverage 63.9 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.009ms, total 34.906s 2022-04-01 03:25:52 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 40: (Coalesce (InsertFields (Let __iruid_6026 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)) (InsertFields (Ref __iruid_6026) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end") (eigen (GetField eigen (GetField __uid_34 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)))) (end (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (Apply position () Int32 (GetField locus (Ref __iruid_6026))) (Apply length () Int32 (Let __iruid_6030 (GetField alleles (Ref __iruid_6026)) (Let __iruid_6031 (I32 0) (Let __iruid_6032 (Str " File \"/h...") (ArrayRef (Ref __iruid_6030) (If (ApplyComparisonOp LT (Ref __iruid_6031) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_6030)) (Ref __iruid_6031)) (Ref __iruid_6031)) (Ref __iruid_6032))))))) (I32 1))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.152ms, total 34.908s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.109ms, total 34.908s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.215ms, total 34.908s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.628ms, total 34.909s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.099ms, total 34.909s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.002ms, total 34.911s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.395ms, total 34.912s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.096ms, total 34.912s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.298ms, total 34.912s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.540ms, total 34.913s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.085ms, total 34.913s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.786ms, total 34.915s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.110ms, total 34.915s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.083ms, total 34.915s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.142ms, total 34.915s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.457ms, total 34.916s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.081ms, total 34.916s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.791ms, total 34.918s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 9.999ms, total 34.918s, tagged coverage 90.7 2022-04-01 03:25:52 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 26: (Coalesce (InsertFields (Let __iruid_6039 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)) (InsertFields (Ref __iruid_6039) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end") (eigen (GetField eigen (GetField __uid_34 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)))) (end (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (Apply position () Int32 (GetField locus (Ref __iruid_6039))) (Apply length () Int32 (ArrayRef (GetField alleles (Ref __iruid_6039)) (I32 0) (Str " File \"/h...")))) (I32 1))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 13.016ms, total 34.919s, tagged coverage 69.7 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.010ms, total 34.919s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 13.187ms, total 34.919s, tagged coverage 68.9 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.013ms, total 34.920s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 6.326ms, total 34.926s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.013ms, total 34.926s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 6.485ms, total 34.926s, tagged coverage 98.0 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.005ms, total 34.927s 2022-04-01 03:25:52 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 26: (Coalesce (InsertFields (Let __iruid_6039 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)) (InsertFields (Ref __iruid_6039) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end") (eigen (GetField eigen (GetField __uid_34 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)))) (end (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (Apply position () Int32 (GetField locus (Ref __iruid_6039))) (Apply length () Int32 (ArrayRef (GetField alleles (Ref __iruid_6039)) (I32 0) (Str " File \"/h...")))) (I32 1))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.100ms, total 34.928s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.089ms, total 34.928s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.147ms, total 34.928s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.432ms, total 34.929s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.077ms, total 34.929s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.824ms, total 34.931s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.108ms, total 34.931s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.085ms, total 34.931s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.133ms, total 34.931s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.419ms, total 34.932s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.079ms, total 34.932s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.702ms, total 34.934s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.125ms, total 34.934s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.082ms, total 34.934s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.138ms, total 34.934s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.431ms, total 34.935s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.079ms, total 34.935s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.827ms, total 34.937s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 8.637ms, total 34.937s, tagged coverage 91.2 2022-04-01 03:25:52 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 26: (Coalesce (InsertFields (Let __iruid_6042 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)) (InsertFields (Ref __iruid_6042) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end") (eigen (GetField eigen (GetField __uid_34 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)))) (end (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (Apply position () Int32 (GetField locus (Ref __iruid_6042))) (Apply length () Int32 (ArrayRef (GetField alleles (Ref __iruid_6042)) (I32 0) (Str " File \"/h...")))) (I32 1))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_34:PCStruct{eigen:PCStruct{Eigen_phred:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 11.560ms, total 34.938s, tagged coverage 68.1 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.009ms, total 34.938s 2022-04-01 03:25:52 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 11.695ms, total 34.938s, tagged coverage 67.5 2022-04-01 03:25:52 root: INFO: encoder cache hit 2022-04-01 03:25:52 MemoryStore: INFO: Block broadcast_17 stored as values in memory (estimated size 104.0 B, free 5.6 GB) 2022-04-01 03:25:52 MemoryStore: INFO: Block broadcast_17_piece0 stored as bytes in memory (estimated size 109.0 B, free 5.6 GB) 2022-04-01 03:25:52 BlockManagerInfo: INFO: Added broadcast_17_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 109.0 B, free: 5.6 GB) 2022-04-01 03:25:52 SparkContext: INFO: Created broadcast 17 from broadcast at SparkBackend.scala:233 2022-04-01 03:25:52 root: INFO: instruction count: 6: __C1201Compiled. 2022-04-01 03:25:52 root: INFO: instruction count: 505: __C1201Compiled.apply 2022-04-01 03:25:52 root: INFO: instruction count: 11: __C1201Compiled.__m1207addIRIntermediate 2022-04-01 03:25:52 root: INFO: instruction count: 8: __C1201Compiled.__m1208addIRIntermediate 2022-04-01 03:25:52 root: INFO: instruction count: 8: __C1201Compiled.__m1209addIRIntermediate 2022-04-01 03:25:52 root: INFO: instruction count: 8: __C1201Compiled.__m1210addIRIntermediate 2022-04-01 03:25:52 root: INFO: instruction count: 11: __C1201Compiled.__m1211addIRIntermediate 2022-04-01 03:25:52 root: INFO: instruction count: 8: __C1201Compiled.__m1212addIRIntermediate 2022-04-01 03:25:52 root: INFO: instruction count: 11: __C1201Compiled.__m1213addIRIntermediate 2022-04-01 03:25:52 root: INFO: instruction count: 11: __C1201Compiled.__m1214addIRIntermediate 2022-04-01 03:25:52 root: INFO: instruction count: 8: __C1201Compiled.__m1215addIRIntermediate 2022-04-01 03:25:52 root: INFO: instruction count: 8: __C1201Compiled.__m1216addIRIntermediate 2022-04-01 03:25:52 root: INFO: instruction count: 11: __C1201Compiled.__m1217addIRIntermediate 2022-04-01 03:25:52 root: INFO: instruction count: 11: __C1201Compiled.__m1221addIRIntermediate 2022-04-01 03:25:52 root: INFO: instruction count: 11: __C1201Compiled.__m1222position 2022-04-01 03:25:52 root: INFO: instruction count: 26: __C1201Compiled.__m1223length 2022-04-01 03:25:52 root: INFO: instruction count: 8: __C1201Compiled.__m1227addIRIntermediate 2022-04-01 03:25:52 root: INFO: instruction count: 14: __C1201Compiled.setPartitionIndex 2022-04-01 03:25:52 root: INFO: instruction count: 7: __C1201Compiled.addPartitionRegion 2022-04-01 03:25:52 root: INFO: instruction count: 25: __C1201Compiled.__m1231DECODE_r_struct_of_r_binaryEND_TO_r_tuple_of_r_stringEND 2022-04-01 03:25:52 root: INFO: instruction count: 11: __C1201Compiled.__m1232read_fields_group_0 2022-04-01 03:25:52 root: INFO: instruction count: 34: __C1201Compiled.__m1233INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:52 root: INFO: instruction count: 41: __C1201Compiled.addLiterals 2022-04-01 03:25:52 root: INFO: instruction count: 204: __C1201Compiled.applyregion95_102 2022-04-01 03:25:52 root: INFO: instruction count: 122: __C1201Compiled.applyregion127_134 2022-04-01 03:25:52 root: INFO: instruction count: 556: __C1201Compiled.applyregion88_146 2022-04-01 03:25:52 root: INFO: instruction count: 188: __C1201Compiled.applyregion0_7 2022-04-01 03:25:52 root: INFO: instruction count: 169: __C1201Compiled.applyregion40_47 2022-04-01 03:25:52 root: INFO: instruction count: 136: __C1201Compiled.applyregion48_55 2022-04-01 03:25:52 root: INFO: instruction count: 122: __C1201Compiled.applyregion32_39 2022-04-01 03:25:52 root: INFO: instruction count: 106: __C1201Compiled.applyregion72_79 2022-04-01 03:25:52 root: INFO: instruction count: 102: __C1201Compiled.applyregion56_63 2022-04-01 03:25:52 root: INFO: instruction count: 6: __C1235applySpills. 2022-04-01 03:25:52 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:25:52 root: INFO: decoder cache hit 2022-04-01 03:25:52 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/parts/part-0' for reading 2022-04-01 03:25:52 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:25:54 root: INFO: decoder cache miss (5 hits, 13 misses, 0.278 2022-04-01 03:25:54 root: INFO: instruction count: 6: __C1258etypeDecode. 2022-04-01 03:25:54 root: INFO: instruction count: 8: __C1258etypeDecode.apply 2022-04-01 03:25:54 root: INFO: instruction count: 47: __C1258etypeDecode.__m1259DECODE_r_struct_of_o_struct_of_r_binaryANDr_int32ENDANDo_array_of_o_binaryANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_struct_of_o_binaryENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryENDANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_int32ENDANDo_float32ANDo_float64END_TO_r_tuple_of_o_locusANDo_array_of_o_stringANDo_tuple_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDEND 2022-04-01 03:25:54 root: INFO: instruction count: 283: __C1258etypeDecode.__m1260read_fields_group_0 2022-04-01 03:25:54 root: INFO: instruction count: 17: __C1258etypeDecode.__m1261INPLACE_DECODE_o_struct_of_r_binaryANDr_int32END_TO_o_tuple_of_r_binaryANDr_int32END 2022-04-01 03:25:54 root: INFO: instruction count: 18: __C1258etypeDecode.__m1262read_fields_group_0 2022-04-01 03:25:54 root: INFO: instruction count: 34: __C1258etypeDecode.__m1263INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:25:54 root: INFO: instruction count: 11: __C1258etypeDecode.__m1264INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:25:54 root: INFO: instruction count: 105: __C1258etypeDecode.__m1265INPLACE_DECODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:25:54 root: INFO: instruction count: 34: __C1258etypeDecode.__m1266INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:25:54 root: INFO: instruction count: 84: __C1258etypeDecode.__m1267SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64END 2022-04-01 03:25:54 root: INFO: instruction count: 6: __C1258etypeDecode.__m1268SKIP_o_int32 2022-04-01 03:25:54 root: INFO: instruction count: 6: __C1258etypeDecode.__m1269SKIP_o_float64 2022-04-01 03:25:54 root: INFO: instruction count: 39: __C1258etypeDecode.__m1270SKIP_o_struct_of_o_binaryEND 2022-04-01 03:25:54 root: INFO: instruction count: 10: __C1258etypeDecode.__m1271SKIP_o_binary 2022-04-01 03:25:54 root: INFO: instruction count: 39: __C1258etypeDecode.__m1272SKIP_o_struct_of_o_float32END 2022-04-01 03:25:54 root: INFO: instruction count: 6: __C1258etypeDecode.__m1273SKIP_o_float32 2022-04-01 03:25:54 root: INFO: instruction count: 39: __C1258etypeDecode.__m1274SKIP_o_struct_of_o_float64END 2022-04-01 03:25:54 root: INFO: instruction count: 144: __C1258etypeDecode.__m1275SKIP_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:25:54 root: INFO: instruction count: 99: __C1258etypeDecode.__m1276SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:25:54 root: INFO: instruction count: 39: __C1258etypeDecode.__m1277SKIP_o_struct_of_o_float64END 2022-04-01 03:25:54 root: INFO: instruction count: 39: __C1258etypeDecode.__m1278SKIP_o_struct_of_o_float32END 2022-04-01 03:25:54 root: INFO: instruction count: 30: __C1258etypeDecode.__m1279INPLACE_DECODE_o_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END_TO_o_tuple_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:25:54 root: INFO: instruction count: 200: __C1258etypeDecode.__m1280read_fields_group_0 2022-04-01 03:25:54 root: INFO: instruction count: 11: __C1258etypeDecode.__m1281INPLACE_DECODE_o_float64_TO_o_float64 2022-04-01 03:25:54 root: INFO: instruction count: 11: __C1258etypeDecode.__m1282INPLACE_DECODE_o_int32_TO_o_int32 2022-04-01 03:25:54 root: INFO: instruction count: 129: __C1258etypeDecode.__m1283SKIP_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:25:54 root: INFO: instruction count: 39: __C1258etypeDecode.__m1284SKIP_o_struct_of_o_int32END 2022-04-01 03:25:57 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:00 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:00 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:01 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:01 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:01 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:01 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:02 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:02 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:04 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:04 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:04 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:04 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:04 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.017ms, total 47.652s 2022-04-01 03:26:05 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 16: (Coalesce (InsertFields (Let __iruid_4342 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)) (InsertFields (Ref __iruid_4342) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac") (exac (GetField exac (GetField __uid_35 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)))) (filters (GetField filters (Ref __iruid_4342))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.265ms, total 47.653s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.066ms, total 47.654s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.118ms, total 47.654s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.430ms, total 47.654s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.074ms, total 47.654s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.103ms, total 47.656s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.096ms, total 47.657s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.062ms, total 47.657s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.107ms, total 47.657s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.312ms, total 47.657s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.116ms, total 47.657s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.935ms, total 47.659s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.086ms, total 47.660s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.064ms, total 47.660s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.099ms, total 47.660s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.334ms, total 47.660s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.045ms, total 47.660s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.524ms, total 47.662s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 8.656ms, total 47.662s, tagged coverage 90.5 2022-04-01 03:26:05 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 16: (Coalesce (InsertFields (Let __iruid_6046 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)) (InsertFields (Ref __iruid_6046) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac") (exac (GetField exac (GetField __uid_35 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)))) (filters (GetField filters (Ref __iruid_6046))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 11.347ms, total 47.663s, tagged coverage 69.0 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.008ms, total 47.663s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 11.580ms, total 47.663s, tagged coverage 67.9 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.010ms, total 47.664s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.032ms, total 47.664s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.010ms, total 47.664s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.141ms, total 47.664s, tagged coverage 37.0 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.003ms, total 47.664s 2022-04-01 03:26:05 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 16: (Coalesce (InsertFields (Let __iruid_6046 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)) (InsertFields (Ref __iruid_6046) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac") (exac (GetField exac (GetField __uid_35 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)))) (filters (GetField filters (Ref __iruid_6046))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.059ms, total 47.665s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.044ms, total 47.665s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.073ms, total 47.665s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.217ms, total 47.665s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.032ms, total 47.666s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.012ms, total 47.667s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.059ms, total 47.667s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.042ms, total 47.667s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.067ms, total 47.667s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.190ms, total 47.667s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.032ms, total 47.667s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.898ms, total 47.668s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.059ms, total 47.668s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.038ms, total 47.668s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.067ms, total 47.668s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.188ms, total 47.668s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.030ms, total 47.668s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.897ms, total 47.669s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 4.442ms, total 47.669s, tagged coverage 90.1 2022-04-01 03:26:05 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 16: (Coalesce (InsertFields (Let __iruid_6049 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)) (InsertFields (Ref __iruid_6049) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac") (exac (GetField exac (GetField __uid_35 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)))) (filters (GetField filters (Ref __iruid_6049))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 6.303ms, total 47.670s, tagged coverage 63.5 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.006ms, total 47.670s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 6.400ms, total 47.670s, tagged coverage 62.7 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.008ms, total 47.671s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 3.499ms, total 47.674s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.008ms, total 47.674s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 3.615ms, total 47.674s, tagged coverage 97.2 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.027ms, total 47.674s 2022-04-01 03:26:05 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 16: (Coalesce (InsertFields (Let __iruid_6049 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)) (InsertFields (Ref __iruid_6049) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac") (exac (GetField exac (GetField __uid_35 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)))) (filters (GetField filters (Ref __iruid_6049))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.061ms, total 47.676s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.045ms, total 47.676s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.072ms, total 47.676s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.285ms, total 47.676s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.034ms, total 47.676s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.972ms, total 47.677s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.058ms, total 47.677s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.039ms, total 47.677s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.065ms, total 47.677s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.191ms, total 47.678s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.030ms, total 47.678s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.987ms, total 47.679s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.056ms, total 47.679s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.038ms, total 47.679s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.064ms, total 47.679s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.187ms, total 47.679s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.030ms, total 47.679s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.938ms, total 47.680s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 4.610ms, total 47.680s, tagged coverage 90.1 2022-04-01 03:26:05 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 16: (Coalesce (InsertFields (Let __iruid_6052 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)) (InsertFields (Ref __iruid_6052) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac") (exac (GetField exac (GetField __uid_35 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)))) (filters (GetField filters (Ref __iruid_6052))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_35:PCStruct{exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 6.532ms, total 47.681s, tagged coverage 63.6 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.006ms, total 47.681s 2022-04-01 03:26:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 6.648ms, total 47.681s, tagged coverage 63.0 2022-04-01 03:26:05 root: INFO: encoder cache hit 2022-04-01 03:26:05 MemoryStore: INFO: Block broadcast_18 stored as values in memory (estimated size 104.0 B, free 5.6 GB) 2022-04-01 03:26:05 MemoryStore: INFO: Block broadcast_18_piece0 stored as bytes in memory (estimated size 109.0 B, free 5.6 GB) 2022-04-01 03:26:05 BlockManagerInfo: INFO: Added broadcast_18_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 109.0 B, free: 5.6 GB) 2022-04-01 03:26:05 SparkContext: INFO: Created broadcast 18 from broadcast at SparkBackend.scala:233 2022-04-01 03:26:05 root: INFO: instruction count: 6: __C1285Compiled. 2022-04-01 03:26:05 root: INFO: instruction count: 434: __C1285Compiled.apply 2022-04-01 03:26:05 root: INFO: instruction count: 11: __C1285Compiled.__m1291addIRIntermediate 2022-04-01 03:26:05 root: INFO: instruction count: 8: __C1285Compiled.__m1292addIRIntermediate 2022-04-01 03:26:05 root: INFO: instruction count: 8: __C1285Compiled.__m1293addIRIntermediate 2022-04-01 03:26:05 root: INFO: instruction count: 8: __C1285Compiled.__m1294addIRIntermediate 2022-04-01 03:26:05 root: INFO: instruction count: 11: __C1285Compiled.__m1295addIRIntermediate 2022-04-01 03:26:05 root: INFO: instruction count: 8: __C1285Compiled.__m1296addIRIntermediate 2022-04-01 03:26:05 root: INFO: instruction count: 11: __C1285Compiled.__m1297addIRIntermediate 2022-04-01 03:26:05 root: INFO: instruction count: 11: __C1285Compiled.__m1298addIRIntermediate 2022-04-01 03:26:05 root: INFO: instruction count: 8: __C1285Compiled.__m1299addIRIntermediate 2022-04-01 03:26:05 root: INFO: instruction count: 8: __C1285Compiled.__m1300addIRIntermediate 2022-04-01 03:26:05 root: INFO: instruction count: 11: __C1285Compiled.__m1301addIRIntermediate 2022-04-01 03:26:05 root: INFO: instruction count: 11: __C1285Compiled.__m1302addIRIntermediate 2022-04-01 03:26:05 root: INFO: instruction count: 11: __C1285Compiled.__m1306addIRIntermediate 2022-04-01 03:26:05 root: INFO: instruction count: 8: __C1285Compiled.__m1310addIRIntermediate 2022-04-01 03:26:05 root: INFO: instruction count: 14: __C1285Compiled.setPartitionIndex 2022-04-01 03:26:05 root: INFO: instruction count: 7: __C1285Compiled.addPartitionRegion 2022-04-01 03:26:05 root: INFO: instruction count: 25: __C1285Compiled.__m1314DECODE_r_struct_of_r_binaryEND_TO_r_tuple_of_r_stringEND 2022-04-01 03:26:05 root: INFO: instruction count: 11: __C1285Compiled.__m1315read_fields_group_0 2022-04-01 03:26:05 root: INFO: instruction count: 34: __C1285Compiled.__m1316INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:26:05 root: INFO: instruction count: 41: __C1285Compiled.addLiterals 2022-04-01 03:26:05 root: INFO: instruction count: 188: __C1285Compiled.applyregion0_7 2022-04-01 03:26:05 root: INFO: instruction count: 183: __C1285Compiled.applyregion40_47 2022-04-01 03:26:05 root: INFO: instruction count: 136: __C1285Compiled.applyregion105_112 2022-04-01 03:26:05 root: INFO: instruction count: 129: __C1285Compiled.applyregion96_104 2022-04-01 03:26:05 root: INFO: instruction count: 123: __C1285Compiled.applyregion48_55 2022-04-01 03:26:05 root: INFO: instruction count: 122: __C1285Compiled.applyregion80_87 2022-04-01 03:26:05 root: INFO: instruction count: 122: __C1285Compiled.applyregion32_39 2022-04-01 03:26:05 root: INFO: instruction count: 109: __C1285Compiled.applyregion145_152 2022-04-01 03:26:05 root: INFO: instruction count: 106: __C1285Compiled.applyregion129_136 2022-04-01 03:26:05 root: INFO: instruction count: 102: __C1285Compiled.applyregion113_120 2022-04-01 03:26:05 root: INFO: instruction count: 102: __C1285Compiled.applyregion64_71 2022-04-01 03:26:05 root: INFO: instruction count: 102: __C1285Compiled.applyregion16_23 2022-04-01 03:26:05 root: INFO: instruction count: 102: __C1285Compiled.applyregion137_144 2022-04-01 03:26:05 root: INFO: instruction count: 104: __C1285Compiled.applyregion88_95 2022-04-01 03:26:05 root: INFO: instruction count: 98: __C1285Compiled.applyregion56_63 2022-04-01 03:26:05 root: INFO: instruction count: 6: __C1318applySpills. 2022-04-01 03:26:05 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:05 root: INFO: decoder cache hit 2022-04-01 03:26:05 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/parts/part-0' for reading 2022-04-01 03:26:05 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:06 root: INFO: decoder cache miss (6 hits, 14 misses, 0.300 2022-04-01 03:26:06 root: INFO: instruction count: 6: __C1343etypeDecode. 2022-04-01 03:26:06 root: INFO: instruction count: 8: __C1343etypeDecode.apply 2022-04-01 03:26:06 root: INFO: instruction count: 47: __C1343etypeDecode.__m1344DECODE_r_struct_of_o_struct_of_r_binaryANDr_int32ENDANDo_array_of_o_binaryANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_struct_of_o_binaryENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryENDANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_int32ENDANDo_float32ANDo_float64END_TO_r_tuple_of_o_locusANDo_array_of_o_stringANDo_tuple_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDEND 2022-04-01 03:26:06 root: INFO: instruction count: 283: __C1343etypeDecode.__m1345read_fields_group_0 2022-04-01 03:26:06 root: INFO: instruction count: 17: __C1343etypeDecode.__m1346INPLACE_DECODE_o_struct_of_r_binaryANDr_int32END_TO_o_tuple_of_r_binaryANDr_int32END 2022-04-01 03:26:06 root: INFO: instruction count: 18: __C1343etypeDecode.__m1347read_fields_group_0 2022-04-01 03:26:06 root: INFO: instruction count: 34: __C1343etypeDecode.__m1348INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:26:06 root: INFO: instruction count: 11: __C1343etypeDecode.__m1349INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:26:06 root: INFO: instruction count: 105: __C1343etypeDecode.__m1350INPLACE_DECODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:26:06 root: INFO: instruction count: 34: __C1343etypeDecode.__m1351INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:26:06 root: INFO: instruction count: 30: __C1343etypeDecode.__m1352INPLACE_DECODE_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64END_TO_o_tuple_of_o_int32ANDo_float64ANDo_int32ANDo_float64END 2022-04-01 03:26:06 root: INFO: instruction count: 116: __C1343etypeDecode.__m1353read_fields_group_0 2022-04-01 03:26:06 root: INFO: instruction count: 11: __C1343etypeDecode.__m1354INPLACE_DECODE_o_int32_TO_o_int32 2022-04-01 03:26:06 root: INFO: instruction count: 11: __C1343etypeDecode.__m1355INPLACE_DECODE_o_float64_TO_o_float64 2022-04-01 03:26:06 root: INFO: instruction count: 39: __C1343etypeDecode.__m1356SKIP_o_struct_of_o_binaryEND 2022-04-01 03:26:06 root: INFO: instruction count: 10: __C1343etypeDecode.__m1357SKIP_o_binary 2022-04-01 03:26:06 root: INFO: instruction count: 39: __C1343etypeDecode.__m1358SKIP_o_struct_of_o_float32END 2022-04-01 03:26:06 root: INFO: instruction count: 6: __C1343etypeDecode.__m1359SKIP_o_float32 2022-04-01 03:26:06 root: INFO: instruction count: 39: __C1343etypeDecode.__m1360SKIP_o_struct_of_o_float64END 2022-04-01 03:26:06 root: INFO: instruction count: 6: __C1343etypeDecode.__m1361SKIP_o_float64 2022-04-01 03:26:06 root: INFO: instruction count: 144: __C1343etypeDecode.__m1362SKIP_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:26:06 root: INFO: instruction count: 99: __C1343etypeDecode.__m1363SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:26:06 root: INFO: instruction count: 6: __C1343etypeDecode.__m1364SKIP_o_int32 2022-04-01 03:26:06 root: INFO: instruction count: 39: __C1343etypeDecode.__m1365SKIP_o_struct_of_o_float64END 2022-04-01 03:26:06 root: INFO: instruction count: 39: __C1343etypeDecode.__m1366SKIP_o_struct_of_o_float32END 2022-04-01 03:26:06 root: INFO: instruction count: 129: __C1343etypeDecode.__m1367SKIP_o_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:26:06 root: INFO: instruction count: 129: __C1343etypeDecode.__m1368SKIP_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:26:06 root: INFO: instruction count: 39: __C1343etypeDecode.__m1369SKIP_o_struct_of_o_int32END 2022-04-01 03:26:10 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:12 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:12 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:12 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:12 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:13 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:13 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:13 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:13 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:14 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:14 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:15 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:15 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:15 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:15 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:16 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.025ms, total 59.431s 2022-04-01 03:26:16 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 21: (Coalesce (InsertFields (Let __iruid_4343 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)) (InsertFields (Ref __iruid_4343) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds") (g1k (GetField g1k (GetField __uid_36 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)))) (geneIds (ToSet (StreamMap __iruid_4344 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_4343))) (GetField gene_id (Ref __iruid_4344))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.286ms, total 59.433s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.067ms, total 59.433s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.107ms, total 59.433s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.274ms, total 59.433s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.043ms, total 59.434s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.281ms, total 59.435s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.072ms, total 59.435s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.057ms, total 59.435s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.091ms, total 59.435s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.264ms, total 59.435s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.043ms, total 59.436s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.254ms, total 59.437s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.107ms, total 59.437s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.081ms, total 59.437s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.094ms, total 59.437s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.245ms, total 59.438s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.038ms, total 59.438s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.158ms, total 59.439s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 6.186ms, total 59.439s, tagged coverage 89.9 2022-04-01 03:26:16 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 21: (Coalesce (InsertFields (Let __iruid_6058 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)) (InsertFields (Ref __iruid_6058) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds") (g1k (GetField g1k (GetField __uid_36 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)))) (geneIds (ToSet (StreamMap __iruid_6059 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_6058))) (GetField gene_id (Ref __iruid_6059))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 8.487ms, total 59.440s, tagged coverage 65.5 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.008ms, total 59.440s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 8.712ms, total 59.440s, tagged coverage 64.2 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.010ms, total 59.440s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.026ms, total 59.440s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.007ms, total 59.440s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.101ms, total 59.440s, tagged coverage 42.5 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.002ms, total 59.441s 2022-04-01 03:26:16 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 21: (Coalesce (InsertFields (Let __iruid_6058 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)) (InsertFields (Ref __iruid_6058) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds") (g1k (GetField g1k (GetField __uid_36 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)))) (geneIds (ToSet (StreamMap __iruid_6059 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_6058))) (GetField gene_id (Ref __iruid_6059))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.109ms, total 59.442s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.074ms, total 59.442s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.119ms, total 59.442s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.271ms, total 59.442s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.039ms, total 59.442s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.111ms, total 59.443s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.064ms, total 59.444s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.046ms, total 59.444s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.080ms, total 59.444s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.240ms, total 59.444s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.065ms, total 59.444s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.076ms, total 59.445s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.061ms, total 59.445s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.046ms, total 59.445s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.078ms, total 59.445s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.289ms, total 59.446s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.037ms, total 59.446s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.156ms, total 59.447s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 5.506ms, total 59.447s, tagged coverage 90.1 2022-04-01 03:26:16 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 21: (Coalesce (InsertFields (Let __iruid_6064 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)) (InsertFields (Ref __iruid_6064) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds") (g1k (GetField g1k (GetField __uid_36 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)))) (geneIds (ToSet (StreamMap __iruid_6065 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_6064))) (GetField gene_id (Ref __iruid_6065))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 7.314ms, total 59.448s, tagged coverage 67.9 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.007ms, total 59.448s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 7.402ms, total 59.448s, tagged coverage 67.2 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.008ms, total 59.448s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 4.863ms, total 59.453s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.010ms, total 59.453s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 4.977ms, total 59.453s, tagged coverage 98.1 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.003ms, total 59.453s 2022-04-01 03:26:16 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 21: (Coalesce (InsertFields (Let __iruid_6064 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)) (InsertFields (Ref __iruid_6064) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds") (g1k (GetField g1k (GetField __uid_36 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)))) (geneIds (ToSet (StreamMap __iruid_6065 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_6064))) (GetField gene_id (Ref __iruid_6065))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.076ms, total 59.455s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.071ms, total 59.455s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.095ms, total 59.455s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.260ms, total 59.455s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.058ms, total 59.455s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.440ms, total 59.457s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.112ms, total 59.457s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.071ms, total 59.457s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.088ms, total 59.457s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.267ms, total 59.457s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.037ms, total 59.457s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.247ms, total 59.459s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.128ms, total 59.459s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.074ms, total 59.459s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.114ms, total 59.459s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.366ms, total 59.459s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.039ms, total 59.460s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.103ms, total 59.461s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 6.246ms, total 59.461s, tagged coverage 90.4 2022-04-01 03:26:16 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 21: (Coalesce (InsertFields (Let __iruid_6070 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)) (InsertFields (Ref __iruid_6070) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds") (g1k (GetField g1k (GetField __uid_36 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)))) (geneIds (ToSet (StreamMap __iruid_6071 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_6070))) (GetField gene_id (Ref __iruid_6071))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_36:PCStruct{g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 8.298ms, total 59.462s, tagged coverage 68.0 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.007ms, total 59.462s 2022-04-01 03:26:16 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 8.389ms, total 59.462s, tagged coverage 67.4 2022-04-01 03:26:16 root: INFO: encoder cache hit 2022-04-01 03:26:16 MemoryStore: INFO: Block broadcast_19 stored as values in memory (estimated size 104.0 B, free 5.6 GB) 2022-04-01 03:26:16 MemoryStore: INFO: Block broadcast_19_piece0 stored as bytes in memory (estimated size 109.0 B, free 5.6 GB) 2022-04-01 03:26:16 BlockManagerInfo: INFO: Added broadcast_19_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 109.0 B, free: 5.6 GB) 2022-04-01 03:26:16 SparkContext: INFO: Created broadcast 19 from broadcast at SparkBackend.scala:233 2022-04-01 03:26:16 root: INFO: instruction count: 6: __C1370Compiled. 2022-04-01 03:26:16 root: INFO: instruction count: 468: __C1370Compiled.apply 2022-04-01 03:26:16 root: INFO: instruction count: 11: __C1370Compiled.__m1376addIRIntermediate 2022-04-01 03:26:16 root: INFO: instruction count: 8: __C1370Compiled.__m1377addIRIntermediate 2022-04-01 03:26:16 root: INFO: instruction count: 8: __C1370Compiled.__m1378addIRIntermediate 2022-04-01 03:26:16 root: INFO: instruction count: 8: __C1370Compiled.__m1379addIRIntermediate 2022-04-01 03:26:16 root: INFO: instruction count: 11: __C1370Compiled.__m1380addIRIntermediate 2022-04-01 03:26:16 root: INFO: instruction count: 8: __C1370Compiled.__m1381addIRIntermediate 2022-04-01 03:26:16 root: INFO: instruction count: 11: __C1370Compiled.__m1382addIRIntermediate 2022-04-01 03:26:16 root: INFO: instruction count: 11: __C1370Compiled.__m1383addIRIntermediate 2022-04-01 03:26:16 root: INFO: instruction count: 8: __C1370Compiled.__m1384addIRIntermediate 2022-04-01 03:26:16 root: INFO: instruction count: 8: __C1370Compiled.__m1385addIRIntermediate 2022-04-01 03:26:16 root: INFO: instruction count: 11: __C1370Compiled.__m1386addIRIntermediate 2022-04-01 03:26:16 root: INFO: instruction count: 11: __C1370Compiled.__m1387addIRIntermediate 2022-04-01 03:26:16 root: INFO: instruction count: 11: __C1370Compiled.__m1388addIRIntermediate 2022-04-01 03:26:16 root: INFO: instruction count: 11: __C1370Compiled.__m1392addIRIntermediate 2022-04-01 03:26:16 root: INFO: instruction count: 15: __C1370Compiled.__m1395setup_jab 2022-04-01 03:26:16 root: INFO: instruction count: 66: __C1370Compiled.__m1396discardNext 2022-04-01 03:26:16 root: INFO: instruction count: 135: __C1370Compiled.__m1397cord 2022-04-01 03:26:16 root: INFO: instruction count: 8: __C1370Compiled.__m1414addIRIntermediate 2022-04-01 03:26:16 root: INFO: instruction count: 14: __C1370Compiled.setPartitionIndex 2022-04-01 03:26:16 root: INFO: instruction count: 7: __C1370Compiled.addPartitionRegion 2022-04-01 03:26:16 root: INFO: instruction count: 25: __C1370Compiled.__m1418DECODE_r_struct_of_r_binaryEND_TO_r_tuple_of_r_stringEND 2022-04-01 03:26:16 root: INFO: instruction count: 11: __C1370Compiled.__m1419read_fields_group_0 2022-04-01 03:26:16 root: INFO: instruction count: 34: __C1370Compiled.__m1420INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:26:16 root: INFO: instruction count: 41: __C1370Compiled.addLiterals 2022-04-01 03:26:16 root: INFO: instruction count: 304: __C1370Compiled.applyregion133_182 2022-04-01 03:26:16 root: INFO: instruction count: 505: __C1370Compiled.applyregion104_199 2022-04-01 03:26:16 root: INFO: instruction count: 188: __C1370Compiled.applyregion0_7 2022-04-01 03:26:16 root: INFO: instruction count: 165: __C1370Compiled.applyregion48_55 2022-04-01 03:26:16 root: INFO: instruction count: 136: __C1370Compiled.applyregion56_63 2022-04-01 03:26:16 root: INFO: instruction count: 122: __C1370Compiled.applyregion232_239 2022-04-01 03:26:16 root: INFO: instruction count: 122: __C1370Compiled.applyregion200_207 2022-04-01 03:26:16 root: INFO: instruction count: 122: __C1370Compiled.applyregion32_39 2022-04-01 03:26:16 root: INFO: instruction count: 106: __C1370Compiled.applyregion80_87 2022-04-01 03:26:16 root: INFO: instruction count: 102: __C1370Compiled.applyregion216_223 2022-04-01 03:26:16 root: INFO: instruction count: 102: __C1370Compiled.applyregion64_71 2022-04-01 03:26:16 root: INFO: instruction count: 102: __C1370Compiled.applyregion16_23 2022-04-01 03:26:16 root: INFO: instruction count: 102: __C1370Compiled.applyregion88_95 2022-04-01 03:26:16 root: INFO: instruction count: 100: __C1370Compiled.applyregion240_247 2022-04-01 03:26:16 root: INFO: instruction count: 100: __C1370Compiled.applyregion40_47 2022-04-01 03:26:16 root: INFO: instruction count: 98: __C1370Compiled.applyregion208_215 2022-04-01 03:26:16 root: INFO: instruction count: 98: __C1370Compiled.applyregion8_15 2022-04-01 03:26:16 root: INFO: instruction count: 98: __C1370Compiled.applyregion224_231 2022-04-01 03:26:16 root: INFO: instruction count: 6: __C1422applySpills. 2022-04-01 03:26:16 root: INFO: instruction count: 6: __C1398sort_compare. 2022-04-01 03:26:16 root: INFO: instruction count: 20: __C1398sort_compare.apply 2022-04-01 03:26:16 root: INFO: instruction count: 21: __C1398sort_compare.apply 2022-04-01 03:26:16 root: INFO: instruction count: 61: __C1398sort_compare.__m1400sort 2022-04-01 03:26:16 root: INFO: instruction count: 26: __C1398sort_compare.__m1401cord 2022-04-01 03:26:16 root: INFO: instruction count: 142: __C1398sort_compare.__m1402cord 2022-04-01 03:26:17 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:17 root: INFO: decoder cache hit 2022-04-01 03:26:17 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/parts/part-0' for reading 2022-04-01 03:26:17 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:18 root: INFO: decoder cache miss (7 hits, 15 misses, 0.318 2022-04-01 03:26:18 root: INFO: instruction count: 6: __C1452etypeDecode. 2022-04-01 03:26:18 root: INFO: instruction count: 8: __C1452etypeDecode.apply 2022-04-01 03:26:18 root: INFO: instruction count: 47: __C1452etypeDecode.__m1453DECODE_r_struct_of_o_struct_of_r_binaryANDr_int32ENDANDo_array_of_o_binaryANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_struct_of_o_binaryENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryENDANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_int32ENDANDo_float32ANDo_float64END_TO_r_tuple_of_o_locusANDo_array_of_o_stringANDo_tuple_of_o_int32ENDEND 2022-04-01 03:26:18 root: INFO: instruction count: 283: __C1452etypeDecode.__m1454read_fields_group_0 2022-04-01 03:26:18 root: INFO: instruction count: 17: __C1452etypeDecode.__m1455INPLACE_DECODE_o_struct_of_r_binaryANDr_int32END_TO_o_tuple_of_r_binaryANDr_int32END 2022-04-01 03:26:18 root: INFO: instruction count: 18: __C1452etypeDecode.__m1456read_fields_group_0 2022-04-01 03:26:18 root: INFO: instruction count: 34: __C1452etypeDecode.__m1457INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:26:18 root: INFO: instruction count: 11: __C1452etypeDecode.__m1458INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:26:18 root: INFO: instruction count: 105: __C1452etypeDecode.__m1459INPLACE_DECODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:26:18 root: INFO: instruction count: 34: __C1452etypeDecode.__m1460INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:26:18 root: INFO: instruction count: 84: __C1452etypeDecode.__m1461SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64END 2022-04-01 03:26:18 root: INFO: instruction count: 6: __C1452etypeDecode.__m1462SKIP_o_int32 2022-04-01 03:26:18 root: INFO: instruction count: 6: __C1452etypeDecode.__m1463SKIP_o_float64 2022-04-01 03:26:18 root: INFO: instruction count: 39: __C1452etypeDecode.__m1464SKIP_o_struct_of_o_binaryEND 2022-04-01 03:26:18 root: INFO: instruction count: 10: __C1452etypeDecode.__m1465SKIP_o_binary 2022-04-01 03:26:18 root: INFO: instruction count: 39: __C1452etypeDecode.__m1466SKIP_o_struct_of_o_float32END 2022-04-01 03:26:18 root: INFO: instruction count: 6: __C1452etypeDecode.__m1467SKIP_o_float32 2022-04-01 03:26:18 root: INFO: instruction count: 39: __C1452etypeDecode.__m1468SKIP_o_struct_of_o_float64END 2022-04-01 03:26:18 root: INFO: instruction count: 144: __C1452etypeDecode.__m1469SKIP_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:26:18 root: INFO: instruction count: 99: __C1452etypeDecode.__m1470SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:26:18 root: INFO: instruction count: 39: __C1452etypeDecode.__m1471SKIP_o_struct_of_o_float64END 2022-04-01 03:26:18 root: INFO: instruction count: 39: __C1452etypeDecode.__m1472SKIP_o_struct_of_o_float32END 2022-04-01 03:26:18 root: INFO: instruction count: 129: __C1452etypeDecode.__m1473SKIP_o_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:26:18 root: INFO: instruction count: 129: __C1452etypeDecode.__m1474SKIP_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:26:18 root: INFO: instruction count: 30: __C1452etypeDecode.__m1475INPLACE_DECODE_o_struct_of_o_int32END_TO_o_tuple_of_o_int32END 2022-04-01 03:26:18 root: INFO: instruction count: 32: __C1452etypeDecode.__m1476read_fields_group_0 2022-04-01 03:26:18 root: INFO: instruction count: 11: __C1452etypeDecode.__m1477INPLACE_DECODE_o_int32_TO_o_int32 2022-04-01 03:26:21 ExecutorAllocationManager: INFO: Request to remove executorIds: 2, 1 2022-04-01 03:26:21 YarnClientSchedulerBackend: INFO: Requesting to kill executor(s) 2, 1 2022-04-01 03:26:21 YarnClientSchedulerBackend: INFO: Actual list of executor(s) to be killed is 2, 1 2022-04-01 03:26:21 ExecutorAllocationManager: INFO: Removing executor 2 because it has been idle for 60 seconds (new desired total will be 1) 2022-04-01 03:26:21 ExecutorAllocationManager: INFO: Removing executor 1 because it has been idle for 60 seconds (new desired total will be 0) 2022-04-01 03:26:22 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:23 YarnSchedulerBackend$YarnDriverEndpoint: INFO: Disabling executor 2. 2022-04-01 03:26:23 DAGScheduler: INFO: Executor lost: 2 (epoch 0) 2022-04-01 03:26:23 BlockManagerMasterEndpoint: INFO: Trying to remove executor 2 from BlockManagerMaster. 2022-04-01 03:26:23 BlockManagerMasterEndpoint: INFO: Removing block manager BlockManagerId(2, ip-172-23-70-80.ec2.internal, 37501, None) 2022-04-01 03:26:23 BlockManagerMaster: INFO: Removed 2 successfully in removeExecutor 2022-04-01 03:26:23 YarnSchedulerBackend$YarnDriverEndpoint: INFO: Disabling executor 1. 2022-04-01 03:26:23 DAGScheduler: INFO: Executor lost: 1 (epoch 0) 2022-04-01 03:26:23 BlockManagerMasterEndpoint: INFO: Trying to remove executor 1 from BlockManagerMaster. 2022-04-01 03:26:23 BlockManagerMasterEndpoint: INFO: Removing block manager BlockManagerId(1, ip-172-23-75-58.ec2.internal, 40133, None) 2022-04-01 03:26:23 BlockManagerMaster: INFO: Removed 1 successfully in removeExecutor 2022-04-01 03:26:23 YarnScheduler: INFO: Executor 2 on ip-172-23-70-80.ec2.internal killed by driver. 2022-04-01 03:26:23 ExecutorAllocationManager: INFO: Existing executor 2 has been removed (new total is 1) 2022-04-01 03:26:23 YarnScheduler: INFO: Executor 1 on ip-172-23-75-58.ec2.internal killed by driver. 2022-04-01 03:26:23 ExecutorAllocationManager: INFO: Existing executor 1 has been removed (new total is 0) 2022-04-01 03:26:24 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:24 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:25 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:25 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:25 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:25 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:26 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:26 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:26 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:26 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:27 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:27 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:28 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:28 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:28 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:28 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:29 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.275ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 116: (Coalesce (InsertFields (StreamAgg __iruid_4345 (StreamFilter __iruid_4346 (StreamRange False (I32 0) (ArrayLen (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! 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[877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) (Ref __iruid_4346) (Str ""))))) (AggLet __iruid_4347 False (ArrayRef (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) (Ref __iruid_4345) (Str "")) (AggLet __iruid_4348 False (ApplyUnaryPrimOp Bang (IsNA (GetField GT (Ref __iruid_4347)))) (AggLet __iruid_4349 False (GetField AD (Ref __iruid_4347)) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes") (geno2mp (GetField geno2mp (GetField __uid_38 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)))) (genotypes (ApplyAggOp Collect () ( (MakeStruct (num_alt (If (Ref __iruid_4348) (Apply nNonRefAlleles () Int32 (GetField GT (Ref __iruid_4347))) (I32 -1))) (gq (If (Ref __iruid_4348) (GetField GQ (Ref __iruid_4347)) (NA Int32))) (ab (Let __iruid_4350 (StreamFold __iruid_4351 __iruid_4352 (StreamFilter __iruid_4353 (ToStream False (Ref __iruid_4349)) (ApplyUnaryPrimOp Bang (IsNA (Ref __iruid_4353)))) (I32 0) (ApplyBinaryPrimOp Add (Ref __iruid_4351) (Ref __iruid_4352))) (If (ApplySpecial land () Boolean (ApplySpecial land () Boolean (Ref __iruid_4348) (ApplyComparisonOp NEQ (Ref __iruid_4350) (I32 0))) (ApplyComparisonOp GT (ArrayLen (Ref __iruid_4349)) (I32 1))) (Cast Float64 (ApplyBinaryPrimOp FloatingPointDivide (ApplyIR indexArray () Int32 (GetField AD (Ref __iruid_4347)) (I32 1) (Str " File \"/h...")) (Ref __iruid_4350))) (NA Float64)))) (dp (If (Ref __iruid_4348) (Cast Float64 (ApplySpecial min_ignore_missing () Int32 (GetField DP (Ref __iruid_4347)) (I32 32000))) (NA Float64))) (ad (If (Ref __iruid_4348) (Apply format () String (Str "%s") (MakeTuple (0) (GetField AD (Ref __iruid_4347)))) (NA String))) (pl (If (Ref __iruid_4348) (Apply format () String (Str "%s") (MakeTuple (0) (GetField PL (Ref __iruid_4347)))) (NA String))) (sample_id (GetField s (ArrayRef (GetField __cols (In +PCStruct{gencodeVersion:+PCString,__cols:+PCArray[+PCStruct{s:+PCString}]} 0)) (Ref __iruid_4345) (Str ""))))))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 1.582ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.311ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.750ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 2.151ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.300ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 3.982ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.529ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.294ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.743ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 1.880ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.300ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 3.035ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.436ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.295ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.675ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 1.946ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.306ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.922ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 23.608ms, total 1m12.4s, tagged coverage 95.0 2022-04-01 03:26:29 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 116: (Coalesce (InsertFields (StreamAgg __iruid_6115 (StreamFilter __iruid_6116 (StreamRange False (I32 0) (ArrayLen (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1))) (I32 1)) (ApplyUnaryPrimOp Bang (IsNA (ArrayRef (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) (Ref __iruid_6116) (Str ""))))) (AggLet __iruid_6117 False (ArrayRef (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) (Ref __iruid_6115) (Str "")) (AggLet __iruid_6118 False (ApplyUnaryPrimOp Bang (IsNA (GetField GT (Ref __iruid_6117)))) (AggLet __iruid_6119 False (GetField AD (Ref __iruid_6117)) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes") (geno2mp (GetField geno2mp (GetField __uid_38 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)))) (genotypes (ApplyAggOp Collect () ( (MakeStruct (num_alt (If (Ref __iruid_6118) (Apply nNonRefAlleles () Int32 (GetField GT (Ref __iruid_6117))) (I32 -1))) (gq (If (Ref __iruid_6118) (GetField GQ (Ref __iruid_6117)) (NA Int32))) (ab (Let __iruid_6120 (StreamFold __iruid_6121 __iruid_6122 (StreamFilter __iruid_6123 (ToStream False (Ref __iruid_6119)) (ApplyUnaryPrimOp Bang (IsNA (Ref __iruid_6123)))) (I32 0) (ApplyBinaryPrimOp Add (Ref __iruid_6121) (Ref __iruid_6122))) (If (ApplySpecial land () Boolean (ApplySpecial land () Boolean (Ref __iruid_6118) (ApplyComparisonOp NEQ (Ref __iruid_6120) (I32 0))) (ApplyComparisonOp GT (ArrayLen (Ref __iruid_6119)) (I32 1))) (Cast Float64 (ApplyBinaryPrimOp FloatingPointDivide (ApplyIR indexArray () Int32 (GetField AD (Ref __iruid_6117)) (I32 1) (Str " File \"/h...")) (Ref __iruid_6120))) (NA Float64)))) (dp (If (Ref __iruid_6118) (Cast Float64 (ApplySpecial min_ignore_missing () Int32 (GetField DP (Ref __iruid_6117)) (I32 32000))) (NA Float64))) (ad (If (Ref __iruid_6118) (Apply format () String (Str "%s") (MakeTuple (0) (GetField AD (Ref __iruid_6117)))) (NA String))) (pl (If (Ref __iruid_6118) (Apply format () String (Str "%s") (MakeTuple (0) (GetField PL (Ref __iruid_6117)))) (NA String))) (sample_id (GetField s (ArrayRef (GetField __cols (In +PCStruct{gencodeVersion:+PCString,__cols:+PCArray[+PCStruct{s:+PCString}]} 0)) (Ref __iruid_6115) (Str ""))))))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 28.888ms, total 1m12.4s, tagged coverage 77.7 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.018ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 29.415ms, total 1m12.4s, tagged coverage 77.3 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.044ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.309ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.067ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.580ms, total 1m12.4s, tagged coverage 72.4 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.014ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 130: (Coalesce (InsertFields (StreamAgg __iruid_6115 (StreamFilter __iruid_6116 (StreamRange False (I32 0) (ArrayLen (GetField `the entries! 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[877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1))) (I32 1)) (ApplyUnaryPrimOp Bang (IsNA (ArrayRef (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) (Ref __iruid_6116) (Str ""))))) (AggLet __iruid_6117 False (ArrayRef (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) (Ref __iruid_6115) (Str "")) (AggLet __iruid_6118 False (ApplyUnaryPrimOp Bang (IsNA (GetField GT (Ref __iruid_6117)))) (AggLet __iruid_6119 False (GetField AD (Ref __iruid_6117)) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes") (geno2mp (GetField geno2mp (GetField __uid_38 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)))) (genotypes (ApplyAggOp Collect () ( (MakeStruct (num_alt (If (Ref __iruid_6118) (Apply nNonRefAlleles () Int32 (GetField GT (Ref __iruid_6117))) (I32 -1))) (gq (If (Ref __iruid_6118) (GetField GQ (Ref __iruid_6117)) (NA Int32))) (ab (Let __iruid_6120 (StreamFold __iruid_6121 __iruid_6122 (StreamFilter __iruid_6123 (ToStream False (Ref __iruid_6119)) (ApplyUnaryPrimOp Bang (IsNA (Ref __iruid_6123)))) (I32 0) (ApplyBinaryPrimOp Add (Ref __iruid_6121) (Ref __iruid_6122))) (If (ApplySpecial land () Boolean (ApplySpecial land () Boolean (Ref __iruid_6118) (ApplyComparisonOp NEQ (Ref __iruid_6120) (I32 0))) (ApplyComparisonOp GT (ArrayLen (Ref __iruid_6119)) (I32 1))) (Cast Float64 (ApplyBinaryPrimOp FloatingPointDivide (Let __iruid_6127 (GetField AD (Ref __iruid_6117)) (Let __iruid_6128 (I32 1) (Let __iruid_6129 (Str " File \"/h...") (ArrayRef (Ref __iruid_6127) (If (ApplyComparisonOp LT (Ref __iruid_6128) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_6127)) (Ref __iruid_6128)) (Ref __iruid_6128)) (Ref __iruid_6129))))) (Ref __iruid_6120))) (NA Float64)))) (dp (If (Ref __iruid_6118) (Cast Float64 (ApplySpecial min_ignore_missing () Int32 (GetField DP (Ref __iruid_6117)) (I32 32000))) (NA Float64))) (ad (If (Ref __iruid_6118) (Apply format () String (Str "%s") (MakeTuple (0) (GetField AD (Ref __iruid_6117)))) (NA String))) (pl (If (Ref __iruid_6118) (Apply format () String (Str "%s") (MakeTuple (0) (GetField PL (Ref __iruid_6117)))) (NA String))) (sample_id (GetField s (ArrayRef (GetField __cols (In +PCStruct{gencodeVersion:+PCString,__cols:+PCArray[+PCStruct{s:+PCString}]} 0)) (Ref __iruid_6115) (Str ""))))))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.212ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.321ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.659ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 2.191ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.308ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 3.007ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.601ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.308ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.729ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 1.993ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.266ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 7.408ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.275ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.293ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.570ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 1.912ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.283ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.874ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 25.320ms, total 1m12.4s, tagged coverage 95.6 2022-04-01 03:26:29 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 116: (Coalesce (InsertFields (StreamAgg __iruid_6152 (StreamFilter __iruid_6153 (StreamRange False (I32 0) (ArrayLen (GetField `the entries! 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[877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1))) (I32 1)) (ApplyUnaryPrimOp Bang (IsNA (ArrayRef (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) (Ref __iruid_6153) (Str ""))))) (AggLet __iruid_6154 False (ArrayRef (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) (Ref __iruid_6152) (Str "")) (AggLet __iruid_6155 False (ApplyUnaryPrimOp Bang (IsNA (GetField GT (Ref __iruid_6154)))) (AggLet __iruid_6156 False (GetField AD (Ref __iruid_6154)) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes") (geno2mp (GetField geno2mp (GetField __uid_38 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)))) (genotypes (ApplyAggOp Collect () ( (MakeStruct (num_alt (If (Ref __iruid_6155) (Apply nNonRefAlleles () Int32 (GetField GT (Ref __iruid_6154))) (I32 -1))) (gq (If (Ref __iruid_6155) (GetField GQ (Ref __iruid_6154)) (NA Int32))) (ab (Let __iruid_6157 (StreamFold __iruid_6158 __iruid_6159 (StreamFilter __iruid_6160 (ToStream False (Ref __iruid_6156)) (ApplyUnaryPrimOp Bang (IsNA (Ref __iruid_6160)))) (I32 0) (ApplyBinaryPrimOp Add (Ref __iruid_6158) (Ref __iruid_6159))) (If (ApplySpecial land () Boolean (ApplySpecial land () Boolean (Ref __iruid_6155) (ApplyComparisonOp NEQ (Ref __iruid_6157) (I32 0))) (ApplyComparisonOp GT (ArrayLen (Ref __iruid_6156)) (I32 1))) (Cast Float64 (ApplyBinaryPrimOp FloatingPointDivide (ArrayRef (GetField AD (Ref __iruid_6154)) (I32 1) (Str " File \"/h...")) (Ref __iruid_6157))) (NA Float64)))) (dp (If (Ref __iruid_6155) (Cast Float64 (ApplySpecial min_ignore_missing () Int32 (GetField DP (Ref __iruid_6154)) (I32 32000))) (NA Float64))) (ad (If (Ref __iruid_6155) (Apply format () String (Str "%s") (MakeTuple (0) (GetField AD (Ref __iruid_6154)))) (NA String))) (pl (If (Ref __iruid_6155) (Apply format () String (Str "%s") (MakeTuple (0) (GetField PL (Ref __iruid_6154)))) (NA String))) (sample_id (GetField s (ArrayRef (GetField __cols (In +PCStruct{gencodeVersion:+PCString,__cols:+PCArray[+PCStruct{s:+PCString}]} 0)) (Ref __iruid_6152) (Str ""))))))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 31.405ms, total 1m12.4s, tagged coverage 77.1 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.017ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 31.604ms, total 1m12.4s, tagged coverage 76.7 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.044ms, total 1m12.4s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 26.618ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.086ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 27.032ms, total 1m12.5s, tagged coverage 99.0 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.015ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 125: (Coalesce (InsertFields (Let __iruid_6161 (RunAgg ( (CollectStateSig +PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString})) (Begin (Begin (InitOp 0 (Collect (CollectStateSig +PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString})) ())) (StreamFor __iruid_6152 (StreamFilter __iruid_6153 (StreamRange False (I32 0) (ArrayLen (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1))) (I32 1)) (ApplyUnaryPrimOp Bang (IsNA (ArrayRef (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) (Ref __iruid_6153) (Str ""))))) (Let __iruid_6154 (ArrayRef (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) (Ref __iruid_6152) (Str "")) (Let __iruid_6155 (ApplyUnaryPrimOp Bang (IsNA (GetField GT (Ref __iruid_6154)))) (Let __iruid_6156 (GetField AD (Ref __iruid_6154)) (Begin (SeqOp 0 (Collect (CollectStateSig +PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString})) ( (MakeStruct (num_alt (If (Ref __iruid_6155) (Apply nNonRefAlleles () Int32 (GetField GT (Ref __iruid_6154))) (I32 -1))) (gq (If (Ref __iruid_6155) (GetField GQ (Ref __iruid_6154)) (NA Int32))) (ab (Let __iruid_6157 (StreamFold __iruid_6158 __iruid_6159 (StreamFilter __iruid_6160 (ToStream False (Ref __iruid_6156)) (ApplyUnaryPrimOp Bang (IsNA (Ref __iruid_6160)))) (I32 0) (ApplyBinaryPrimOp Add (Ref __iruid_6158) (Ref __iruid_6159))) (If (ApplySpecial land () Boolean (ApplySpecial land () Boolean (Ref __iruid_6155) (ApplyComparisonOp NEQ (Ref __iruid_6157) (I32 0))) (ApplyComparisonOp GT (ArrayLen (Ref __iruid_6156)) (I32 1))) (Cast Float64 (ApplyBinaryPrimOp FloatingPointDivide (ArrayRef (GetField AD (Ref __iruid_6154)) (I32 1) (Str " File \"/h...")) (Ref __iruid_6157))) (NA Float64)))) (dp (If (Ref __iruid_6155) (Cast Float64 (ApplySpecial min_ignore_missing () Int32 (GetField DP (Ref __iruid_6154)) (I32 32000))) (NA Float64))) (ad (If (Ref __iruid_6155) (Apply format () String (Str "%s") (MakeTuple (0) (GetField AD (Ref __iruid_6154)))) (NA String))) (pl (If (Ref __iruid_6155) (Apply format () String (Str "%s") (MakeTuple (0) (GetField PL (Ref __iruid_6154)))) (NA String))) (sample_id (GetField s (ArrayRef (GetField __cols (In +PCStruct{gencodeVersion:+PCString,__cols:+PCArray[+PCStruct{s:+PCString}]} 0)) (Ref __iruid_6152) (Str ""))))))))))))) (ResultOp 0 ( (Collect (CollectStateSig +PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}))))) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes") (geno2mp (GetField geno2mp (GetField __uid_38 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)))) (genotypes (GetTupleElement 0 (Ref __iruid_6161))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.524ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 1.113ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 1.195ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 4.402ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.892ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 4.978ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.770ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.315ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.985ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 3.381ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.955ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 3.775ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.541ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.203ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.711ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 2.033ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.484ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.598ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 30.852ms, total 1m12.5s, tagged coverage 96.8 2022-04-01 03:26:29 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 125: (Coalesce (InsertFields (Let __iruid_6182 (RunAgg ( (CollectStateSig +PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString})) (Begin (Begin (InitOp 0 (Collect (CollectStateSig +PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString})) ())) (StreamFor __iruid_6183 (StreamFilter __iruid_6184 (StreamRange False (I32 0) (ArrayLen (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1))) (I32 1)) (ApplyUnaryPrimOp Bang (IsNA (ArrayRef (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) (Ref __iruid_6184) (Str ""))))) (Let __iruid_6185 (ArrayRef (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) (Ref __iruid_6183) (Str "")) (Let __iruid_6186 (ApplyUnaryPrimOp Bang (IsNA (GetField GT (Ref __iruid_6185)))) (Let __iruid_6187 (GetField AD (Ref __iruid_6185)) (Begin (SeqOp 0 (Collect (CollectStateSig +PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString})) ( (MakeStruct (num_alt (If (Ref __iruid_6186) (Apply nNonRefAlleles () Int32 (GetField GT (Ref __iruid_6185))) (I32 -1))) (gq (If (Ref __iruid_6186) (GetField GQ (Ref __iruid_6185)) (NA Int32))) (ab (Let __iruid_6188 (StreamFold __iruid_6189 __iruid_6190 (StreamFilter __iruid_6191 (ToStream False (Ref __iruid_6187)) (ApplyUnaryPrimOp Bang (IsNA (Ref __iruid_6191)))) (I32 0) (ApplyBinaryPrimOp Add (Ref __iruid_6189) (Ref __iruid_6190))) (If (ApplySpecial land () Boolean (ApplySpecial land () Boolean (Ref __iruid_6186) (ApplyComparisonOp NEQ (Ref __iruid_6188) (I32 0))) (ApplyComparisonOp GT (ArrayLen (Ref __iruid_6187)) (I32 1))) (Cast Float64 (ApplyBinaryPrimOp FloatingPointDivide (ArrayRef (GetField AD (Ref __iruid_6185)) (I32 1) (Str " File \"/h...")) (Ref __iruid_6188))) (NA Float64)))) (dp (If (Ref __iruid_6186) (Cast Float64 (ApplySpecial min_ignore_missing () Int32 (GetField DP (Ref __iruid_6185)) (I32 32000))) (NA Float64))) (ad (If (Ref __iruid_6186) (Apply format () String (Str "%s") (MakeTuple (0) (GetField AD (Ref __iruid_6185)))) (NA String))) (pl (If (Ref __iruid_6186) (Apply format () String (Str "%s") (MakeTuple (0) (GetField PL (Ref __iruid_6185)))) (NA String))) (sample_id (GetField s (ArrayRef (GetField __cols (In +PCStruct{gencodeVersion:+PCString,__cols:+PCArray[+PCStruct{s:+PCString}]} 0)) (Ref __iruid_6183) (Str ""))))))))))))) (ResultOp 0 ( (Collect (CollectStateSig +PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}))))) (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes") (geno2mp (GetField geno2mp (GetField __uid_38 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)))) (genotypes (GetTupleElement 0 (Ref __iruid_6182))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_38:PCStruct{geno2mp:PCStruct{HPO_Count:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 38.515ms, total 1m12.5s, tagged coverage 77.5 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.019ms, total 1m12.5s 2022-04-01 03:26:29 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 38.727ms, total 1m12.5s, tagged coverage 77.2 2022-04-01 03:26:29 root: INFO: encoder cache hit 2022-04-01 03:26:29 MemoryStore: INFO: Block broadcast_20 stored as values in memory (estimated size 112.0 B, free 5.6 GB) 2022-04-01 03:26:29 MemoryStore: INFO: Block broadcast_20_piece0 stored as bytes in memory (estimated size 115.0 B, free 5.6 GB) 2022-04-01 03:26:29 BlockManagerInfo: INFO: Added broadcast_20_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 115.0 B, free: 5.6 GB) 2022-04-01 03:26:29 SparkContext: INFO: Created broadcast 20 from broadcast at SparkBackend.scala:233 2022-04-01 03:26:30 root: INFO: instruction count: 6: __C1478Compiled. 2022-04-01 03:26:30 root: INFO: instruction count: 249: __C1478Compiled.apply 2022-04-01 03:26:30 root: INFO: instruction count: 9: __C1478Compiled.__m1510nNonRefAlleles 2022-04-01 03:26:30 root: INFO: instruction count: 50: __C1478Compiled.__m1521cord 2022-04-01 03:26:30 root: INFO: instruction count: 26: __C1478Compiled.__m1522cord 2022-04-01 03:26:30 root: INFO: instruction count: 82: __C1478Compiled.__m1523format 2022-04-01 03:26:30 root: INFO: instruction count: 15: __C1478Compiled.__m1526setup_null 2022-04-01 03:26:30 root: INFO: instruction count: 8: __C1478Compiled.__m1532addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 8: __C1478Compiled.__m1533addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 8: __C1478Compiled.__m1536addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 134: __C1478Compiled.__m1537blockLinkedListPush 2022-04-01 03:26:30 root: INFO: instruction count: 158: __C1478Compiled.__m1538deepCopy 2022-04-01 03:26:30 root: INFO: instruction count: 11: __C1478Compiled.__m1552addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 8: __C1478Compiled.__m1553addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 8: __C1478Compiled.__m1554addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 11: __C1478Compiled.__m1555addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 11: __C1478Compiled.__m1556addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 11: __C1478Compiled.__m1557addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 8: __C1478Compiled.__m1558addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 8: __C1478Compiled.__m1559addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 11: __C1478Compiled.__m1560addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 11: __C1478Compiled.__m1561addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 11: __C1478Compiled.__m1562addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 11: __C1478Compiled.__m1563addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 11: __C1478Compiled.__m1567addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 8: __C1478Compiled.__m1568addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 8: __C1478Compiled.__m1572addIRIntermediate 2022-04-01 03:26:30 root: INFO: instruction count: 14: __C1478Compiled.setPartitionIndex 2022-04-01 03:26:30 root: INFO: instruction count: 7: __C1478Compiled.addPartitionRegion 2022-04-01 03:26:30 root: INFO: instruction count: 25: __C1478Compiled.__m1576DECODE_r_struct_of_r_binaryANDr_binaryEND_TO_r_tuple_of_r_stringANDr_stringEND 2022-04-01 03:26:30 root: INFO: instruction count: 18: __C1478Compiled.__m1577read_fields_group_0 2022-04-01 03:26:30 root: INFO: instruction count: 34: __C1478Compiled.__m1578INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:26:30 root: INFO: instruction count: 50: __C1478Compiled.addLiterals 2022-04-01 03:26:30 root: INFO: instruction count: 230: __C1478Compiled.applyregion57_85 2022-04-01 03:26:30 root: INFO: instruction count: 200: __C1478Compiled.applyregion173_185 2022-04-01 03:26:30 root: INFO: instruction count: 213: __C1478Compiled.applyregion115_134 2022-04-01 03:26:30 root: INFO: instruction count: 163: __C1478Compiled.applyregion160_172 2022-04-01 03:26:30 root: INFO: instruction count: 144: __C1478Compiled.applyregion135_159 2022-04-01 03:26:30 root: INFO: instruction count: 219: __C1478Compiled.applyregion192_198 2022-04-01 03:26:30 root: INFO: instruction count: 152: __C1478Compiled.applyregion311_319 2022-04-01 03:26:30 root: INFO: instruction count: 136: __C1478Compiled.applyregion199_206 2022-04-01 03:26:30 root: INFO: instruction count: 122: __C1478Compiled.applyregion352_359 2022-04-01 03:26:30 root: INFO: instruction count: 122: __C1478Compiled.applyregion320_327 2022-04-01 03:26:30 root: INFO: instruction count: 122: __C1478Compiled.applyregion287_294 2022-04-01 03:26:30 root: INFO: instruction count: 122: __C1478Compiled.applyregion255_262 2022-04-01 03:26:30 root: INFO: instruction count: 116: __C1478Compiled.applyregion247_254 2022-04-01 03:26:30 root: INFO: instruction count: 115: __C1478Compiled.applyregion376_383 2022-04-01 03:26:30 root: INFO: instruction count: 106: __C1478Compiled.applyregion223_230 2022-04-01 03:26:30 root: INFO: instruction count: 102: __C1478Compiled.applyregion336_343 2022-04-01 03:26:30 root: INFO: instruction count: 102: __C1478Compiled.applyregion271_278 2022-04-01 03:26:30 root: INFO: instruction count: 102: __C1478Compiled.applyregion207_214 2022-04-01 03:26:30 root: INFO: instruction count: 102: __C1478Compiled.applyregion231_238 2022-04-01 03:26:30 root: INFO: instruction count: 100: __C1478Compiled.applyregion360_367 2022-04-01 03:26:30 root: INFO: instruction count: 100: __C1478Compiled.applyregion295_302 2022-04-01 03:26:30 root: INFO: instruction count: 98: __C1478Compiled.applyregion328_335 2022-04-01 03:26:30 root: INFO: instruction count: 98: __C1478Compiled.applyregion263_270 2022-04-01 03:26:30 root: INFO: instruction count: 98: __C1478Compiled.applyregion344_351 2022-04-01 03:26:30 root: INFO: instruction count: 98: __C1478Compiled.applyregion279_286 2022-04-01 03:26:30 root: INFO: instruction count: 566: __C1478Compiled.applyregion191_393 2022-04-01 03:26:30 root: INFO: instruction count: 847: __C1478Compiled.applyregion14_394 2022-04-01 03:26:30 root: INFO: instruction count: 6: __C1580applySpills. 2022-04-01 03:26:30 root: INFO: encoder cache miss (9 hits, 9 misses, 0.500) 2022-04-01 03:26:30 root: INFO: instruction count: 6: __C1627etypeEncode. 2022-04-01 03:26:30 root: INFO: instruction count: 8: __C1627etypeEncode.apply 2022-04-01 03:26:30 root: INFO: instruction count: 26: __C1627etypeEncode.__m1628ENCODE_r_tuple_of_r_stringANDr_array_of_r_tuple_of_r_stringENDEND_TO_r_struct_of_r_binaryANDr_array_of_r_struct_of_r_binaryENDEND 2022-04-01 03:26:30 root: INFO: instruction count: 19: __C1627etypeEncode.__m1629ENCODE_r_binary_TO_r_binary 2022-04-01 03:26:30 root: INFO: instruction count: 53: __C1627etypeEncode.__m1630ENCODE_r_array_of_r_tuple_of_r_binaryEND_TO_r_array_of_r_struct_of_r_binaryEND 2022-04-01 03:26:30 root: INFO: instruction count: 16: __C1627etypeEncode.__m1631ENCODE_r_tuple_of_r_binaryEND_TO_r_struct_of_r_binaryEND 2022-04-01 03:26:30 root: INFO: decoder cache miss (7 hits, 16 misses, 0.304 2022-04-01 03:26:30 root: INFO: instruction count: 6: __C1632etypeDecode. 2022-04-01 03:26:30 root: INFO: instruction count: 8: __C1632etypeDecode.apply 2022-04-01 03:26:30 root: INFO: instruction count: 25: __C1632etypeDecode.__m1633DECODE_r_struct_of_r_binaryANDr_array_of_r_struct_of_r_binaryENDEND_TO_r_tuple_of_r_stringANDr_array_of_r_tuple_of_r_stringENDEND 2022-04-01 03:26:30 root: INFO: instruction count: 18: __C1632etypeDecode.__m1634read_fields_group_0 2022-04-01 03:26:30 root: INFO: instruction count: 34: __C1632etypeDecode.__m1635INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:26:30 root: INFO: instruction count: 58: __C1632etypeDecode.__m1636INPLACE_DECODE_r_array_of_r_struct_of_r_binaryEND_TO_r_array_of_r_tuple_of_r_binaryEND 2022-04-01 03:26:30 root: INFO: instruction count: 17: __C1632etypeDecode.__m1637INPLACE_DECODE_r_struct_of_r_binaryEND_TO_r_tuple_of_r_binaryEND 2022-04-01 03:26:30 root: INFO: instruction count: 11: __C1632etypeDecode.__m1638read_fields_group_0 2022-04-01 03:26:30 MemoryStore: INFO: Block broadcast_21 stored as values in memory (estimated size 7.2 KB, free 5.6 GB) 2022-04-01 03:26:30 MemoryStore: INFO: Block broadcast_21_piece0 stored as bytes in memory (estimated size 2.7 KB, free 5.6 GB) 2022-04-01 03:26:30 BlockManagerInfo: INFO: Added broadcast_21_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 2.7 KB, free: 5.6 GB) 2022-04-01 03:26:30 SparkContext: INFO: Created broadcast 21 from broadcast at SparkBackend.scala:233 2022-04-01 03:26:30 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:30 root: INFO: decoder cache hit 2022-04-01 03:26:30 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/parts/part-0' for reading 2022-04-01 03:26:30 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:31 root: INFO: decoder cache miss (8 hits, 17 misses, 0.320 2022-04-01 03:26:31 root: INFO: instruction count: 6: __C1639etypeDecode. 2022-04-01 03:26:31 root: INFO: instruction count: 8: __C1639etypeDecode.apply 2022-04-01 03:26:31 root: INFO: instruction count: 47: __C1639etypeDecode.__m1640DECODE_r_struct_of_o_struct_of_r_binaryANDr_int32ENDANDo_array_of_o_binaryANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_struct_of_o_binaryENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryENDANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_int32ENDANDo_float32ANDo_float64END_TO_r_tuple_of_o_locusANDo_array_of_o_stringANDo_float64END 2022-04-01 03:26:31 root: INFO: instruction count: 283: __C1639etypeDecode.__m1641read_fields_group_0 2022-04-01 03:26:31 root: INFO: instruction count: 17: __C1639etypeDecode.__m1642INPLACE_DECODE_o_struct_of_r_binaryANDr_int32END_TO_o_tuple_of_r_binaryANDr_int32END 2022-04-01 03:26:31 root: INFO: instruction count: 18: __C1639etypeDecode.__m1643read_fields_group_0 2022-04-01 03:26:31 root: INFO: instruction count: 34: __C1639etypeDecode.__m1644INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:26:31 root: INFO: instruction count: 11: __C1639etypeDecode.__m1645INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:26:31 root: INFO: instruction count: 105: __C1639etypeDecode.__m1646INPLACE_DECODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:26:31 root: INFO: instruction count: 34: __C1639etypeDecode.__m1647INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:26:31 root: INFO: instruction count: 84: __C1639etypeDecode.__m1648SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64END 2022-04-01 03:26:31 root: INFO: instruction count: 6: __C1639etypeDecode.__m1649SKIP_o_int32 2022-04-01 03:26:31 root: INFO: instruction count: 6: __C1639etypeDecode.__m1650SKIP_o_float64 2022-04-01 03:26:31 root: INFO: instruction count: 39: __C1639etypeDecode.__m1651SKIP_o_struct_of_o_binaryEND 2022-04-01 03:26:31 root: INFO: instruction count: 10: __C1639etypeDecode.__m1652SKIP_o_binary 2022-04-01 03:26:31 root: INFO: instruction count: 39: __C1639etypeDecode.__m1653SKIP_o_struct_of_o_float32END 2022-04-01 03:26:31 root: INFO: instruction count: 6: __C1639etypeDecode.__m1654SKIP_o_float32 2022-04-01 03:26:31 root: INFO: instruction count: 39: __C1639etypeDecode.__m1655SKIP_o_struct_of_o_float64END 2022-04-01 03:26:31 root: INFO: instruction count: 144: __C1639etypeDecode.__m1656SKIP_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:26:31 root: INFO: instruction count: 99: __C1639etypeDecode.__m1657SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:26:31 root: INFO: instruction count: 39: __C1639etypeDecode.__m1658SKIP_o_struct_of_o_float64END 2022-04-01 03:26:31 root: INFO: instruction count: 39: __C1639etypeDecode.__m1659SKIP_o_struct_of_o_float32END 2022-04-01 03:26:31 root: INFO: instruction count: 129: __C1639etypeDecode.__m1660SKIP_o_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:26:31 root: INFO: instruction count: 129: __C1639etypeDecode.__m1661SKIP_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:26:31 root: INFO: instruction count: 39: __C1639etypeDecode.__m1662SKIP_o_struct_of_o_int32END 2022-04-01 03:26:31 root: INFO: instruction count: 11: __C1639etypeDecode.__m1663INPLACE_DECODE_o_float64_TO_o_float64 2022-04-01 03:26:36 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:37 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:37 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:39 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:39 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:39 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:39 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:40 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:40 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:41 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:41 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:41 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:41 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:42 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:42 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:43 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:43 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:44 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:44 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:45 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.046ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_41:PCStruct{gnomad_exome_coverage:PFloat64}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_exome_coverage (GetField gnomad_exome_coverage (GetField __uid_41 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_41:PCStruct{gnomad_exome_coverage:PFloat64}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.596ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.037ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.080ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.279ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.033ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.794ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 2.089ms, total 1m27.7s, tagged coverage 87.1 2022-04-01 03:26:45 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_41:PCStruct{gnomad_exome_coverage:PFloat64}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_exome_coverage (GetField gnomad_exome_coverage (GetField __uid_41 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_41:PCStruct{gnomad_exome_coverage:PFloat64}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 3.664ms, total 1m27.7s, tagged coverage 49.6 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.005ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 4.145ms, total 1m27.7s, tagged coverage 45.1 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.007ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.012ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.004ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.073ms, total 1m27.7s, tagged coverage 32.6 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.002ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_41:PCStruct{gnomad_exome_coverage:PFloat64}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_exome_coverage (GetField gnomad_exome_coverage (GetField __uid_41 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_41:PCStruct{gnomad_exome_coverage:PFloat64}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.093ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.032ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.069ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.146ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.026ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.702ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 1.262ms, total 1m27.7s, tagged coverage 84.5 2022-04-01 03:26:45 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_41:PCStruct{gnomad_exome_coverage:PFloat64}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_exome_coverage (GetField gnomad_exome_coverage (GetField __uid_41 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_41:PCStruct{gnomad_exome_coverage:PFloat64}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 2.713ms, total 1m27.7s, tagged coverage 39.3 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.004ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 2.969ms, total 1m27.7s, tagged coverage 36.1 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.006ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 2.795ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.009ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 3.044ms, total 1m27.7s, tagged coverage 92.3 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.002ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_41:PCStruct{gnomad_exome_coverage:PFloat64}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_exome_coverage (GetField gnomad_exome_coverage (GetField __uid_41 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_41:PCStruct{gnomad_exome_coverage:PFloat64}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.049ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.036ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.075ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.193ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.036ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.623ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 1.358ms, total 1m27.7s, tagged coverage 74.5 2022-04-01 03:26:45 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_41:PCStruct{gnomad_exome_coverage:PFloat64}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_exome_coverage (GetField gnomad_exome_coverage (GetField __uid_41 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_41:PCStruct{gnomad_exome_coverage:PFloat64}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 3.263ms, total 1m27.7s, tagged coverage 31.0 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.004ms, total 1m27.7s 2022-04-01 03:26:45 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 3.371ms, total 1m27.7s, tagged coverage 30.2 2022-04-01 03:26:45 root: INFO: encoder cache hit 2022-04-01 03:26:45 MemoryStore: INFO: Block broadcast_22 stored as values in memory (estimated size 104.0 B, free 5.6 GB) 2022-04-01 03:26:45 MemoryStore: INFO: Block broadcast_22_piece0 stored as bytes in memory (estimated size 109.0 B, free 5.6 GB) 2022-04-01 03:26:45 BlockManagerInfo: INFO: Added broadcast_22_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 109.0 B, free: 5.6 GB) 2022-04-01 03:26:45 SparkContext: INFO: Created broadcast 22 from broadcast at SparkBackend.scala:233 2022-04-01 03:26:45 root: INFO: instruction count: 6: __C1664Compiled. 2022-04-01 03:26:45 root: INFO: instruction count: 446: __C1664Compiled.apply 2022-04-01 03:26:45 root: INFO: instruction count: 11: __C1664Compiled.__m1668addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 8: __C1664Compiled.__m1669addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 8: __C1664Compiled.__m1670addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 8: __C1664Compiled.__m1671addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 11: __C1664Compiled.__m1672addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 8: __C1664Compiled.__m1673addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 11: __C1664Compiled.__m1674addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 11: __C1664Compiled.__m1675addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 8: __C1664Compiled.__m1676addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 8: __C1664Compiled.__m1677addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 11: __C1664Compiled.__m1678addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 11: __C1664Compiled.__m1679addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 11: __C1664Compiled.__m1680addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 11: __C1664Compiled.__m1681addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 11: __C1664Compiled.__m1682addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 8: __C1664Compiled.__m1683addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 8: __C1664Compiled.__m1684addIRIntermediate 2022-04-01 03:26:45 root: INFO: instruction count: 14: __C1664Compiled.setPartitionIndex 2022-04-01 03:26:45 root: INFO: instruction count: 7: __C1664Compiled.addPartitionRegion 2022-04-01 03:26:45 root: INFO: instruction count: 25: __C1664Compiled.__m1691DECODE_r_struct_of_r_binaryEND_TO_r_tuple_of_r_stringEND 2022-04-01 03:26:45 root: INFO: instruction count: 11: __C1664Compiled.__m1692read_fields_group_0 2022-04-01 03:26:45 root: INFO: instruction count: 34: __C1664Compiled.__m1693INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:26:45 root: INFO: instruction count: 41: __C1664Compiled.addLiterals 2022-04-01 03:26:45 root: INFO: instruction count: 212: __C1664Compiled.applyregion0_7 2022-04-01 03:26:45 root: INFO: instruction count: 156: __C1664Compiled.applyregion56_63 2022-04-01 03:26:45 root: INFO: instruction count: 122: __C1664Compiled.applyregion96_103 2022-04-01 03:26:45 root: INFO: instruction count: 122: __C1664Compiled.applyregion64_71 2022-04-01 03:26:45 root: INFO: instruction count: 122: __C1664Compiled.applyregion32_39 2022-04-01 03:26:45 root: INFO: instruction count: 102: __C1664Compiled.applyregion80_87 2022-04-01 03:26:45 root: INFO: instruction count: 102: __C1664Compiled.applyregion16_23 2022-04-01 03:26:45 root: INFO: instruction count: 106: __C1664Compiled.applyregion120_127 2022-04-01 03:26:45 root: INFO: instruction count: 100: __C1664Compiled.applyregion104_111 2022-04-01 03:26:45 root: INFO: instruction count: 100: __C1664Compiled.applyregion40_47 2022-04-01 03:26:45 root: INFO: instruction count: 98: __C1664Compiled.applyregion72_79 2022-04-01 03:26:45 root: INFO: instruction count: 98: __C1664Compiled.applyregion8_15 2022-04-01 03:26:45 root: INFO: instruction count: 6: __C1695applySpills. 2022-04-01 03:26:45 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:45 root: INFO: decoder cache hit 2022-04-01 03:26:45 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/parts/part-0' for reading 2022-04-01 03:26:45 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:46 root: INFO: decoder cache miss (9 hits, 18 misses, 0.333 2022-04-01 03:26:46 root: INFO: instruction count: 6: __C1717etypeDecode. 2022-04-01 03:26:46 root: INFO: instruction count: 8: __C1717etypeDecode.apply 2022-04-01 03:26:46 root: INFO: instruction count: 47: __C1717etypeDecode.__m1718DECODE_r_struct_of_o_struct_of_r_binaryANDr_int32ENDANDo_array_of_o_binaryANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_struct_of_o_binaryENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryENDANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_int32ENDANDo_float32ANDo_float64END_TO_r_tuple_of_o_locusANDo_array_of_o_stringANDo_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDEND 2022-04-01 03:26:46 root: INFO: instruction count: 283: __C1717etypeDecode.__m1719read_fields_group_0 2022-04-01 03:26:46 root: INFO: instruction count: 17: __C1717etypeDecode.__m1720INPLACE_DECODE_o_struct_of_r_binaryANDr_int32END_TO_o_tuple_of_r_binaryANDr_int32END 2022-04-01 03:26:46 root: INFO: instruction count: 18: __C1717etypeDecode.__m1721read_fields_group_0 2022-04-01 03:26:46 root: INFO: instruction count: 34: __C1717etypeDecode.__m1722INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:26:46 root: INFO: instruction count: 11: __C1717etypeDecode.__m1723INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:26:46 root: INFO: instruction count: 105: __C1717etypeDecode.__m1724INPLACE_DECODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:26:46 root: INFO: instruction count: 34: __C1717etypeDecode.__m1725INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:26:46 root: INFO: instruction count: 84: __C1717etypeDecode.__m1726SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64END 2022-04-01 03:26:46 root: INFO: instruction count: 6: __C1717etypeDecode.__m1727SKIP_o_int32 2022-04-01 03:26:46 root: INFO: instruction count: 6: __C1717etypeDecode.__m1728SKIP_o_float64 2022-04-01 03:26:46 root: INFO: instruction count: 39: __C1717etypeDecode.__m1729SKIP_o_struct_of_o_binaryEND 2022-04-01 03:26:46 root: INFO: instruction count: 10: __C1717etypeDecode.__m1730SKIP_o_binary 2022-04-01 03:26:46 root: INFO: instruction count: 39: __C1717etypeDecode.__m1731SKIP_o_struct_of_o_float32END 2022-04-01 03:26:46 root: INFO: instruction count: 6: __C1717etypeDecode.__m1732SKIP_o_float32 2022-04-01 03:26:46 root: INFO: instruction count: 39: __C1717etypeDecode.__m1733SKIP_o_struct_of_o_float64END 2022-04-01 03:26:46 root: INFO: instruction count: 144: __C1717etypeDecode.__m1734SKIP_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:26:46 root: INFO: instruction count: 99: __C1717etypeDecode.__m1735SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:26:46 root: INFO: instruction count: 39: __C1717etypeDecode.__m1736SKIP_o_struct_of_o_float64END 2022-04-01 03:26:46 root: INFO: instruction count: 39: __C1717etypeDecode.__m1737SKIP_o_struct_of_o_float32END 2022-04-01 03:26:46 root: INFO: instruction count: 129: __C1717etypeDecode.__m1738SKIP_o_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:26:46 root: INFO: instruction count: 129: __C1717etypeDecode.__m1739SKIP_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:26:46 root: INFO: instruction count: 30: __C1717etypeDecode.__m1740INPLACE_DECODE_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END_TO_o_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:26:46 root: INFO: instruction count: 200: __C1717etypeDecode.__m1741read_fields_group_0 2022-04-01 03:26:46 root: INFO: instruction count: 11: __C1717etypeDecode.__m1742INPLACE_DECODE_o_float64_TO_o_float64 2022-04-01 03:26:46 root: INFO: instruction count: 11: __C1717etypeDecode.__m1743INPLACE_DECODE_o_int32_TO_o_int32 2022-04-01 03:26:46 root: INFO: instruction count: 39: __C1717etypeDecode.__m1744SKIP_o_struct_of_o_int32END 2022-04-01 03:26:51 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:52 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:52 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:53 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:53 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:54 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:54 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:54 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:55 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:55 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:55 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:56 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:56 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:56 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:57 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:58 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:58 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:59 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:59 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:26:59 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:26:59 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:00 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.010ms, total 1m42.9s 2022-04-01 03:27:00 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_42:PCStruct{gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_exomes (GetField gnomad_exomes (GetField __uid_42 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_42:PCStruct{gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.217ms, total 1m42.9s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.036ms, total 1m42.9s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.081ms, total 1m42.9s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.214ms, total 1m42.9s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.044ms, total 1m42.9s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.817ms, total 1m42.9s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 1.638ms, total 1m42.9s, tagged coverage 86.1 2022-04-01 03:27:00 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_42:PCStruct{gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_exomes (GetField gnomad_exomes (GetField __uid_42 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_42:PCStruct{gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 3.633ms, total 1m42.9s, tagged coverage 38.8 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.006ms, total 1m42.9s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 3.872ms, total 1m42.9s, tagged coverage 36.8 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.010ms, total 1m42.9s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.024ms, total 1m42.9s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.007ms, total 1m42.9s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.196ms, total 1m42.9s, tagged coverage 20.8 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.003ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_42:PCStruct{gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_exomes (GetField gnomad_exomes (GetField __uid_42 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_42:PCStruct{gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.060ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.040ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.082ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.213ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.045ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.778ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 1.466ms, total 1m43.0s, tagged coverage 83.1 2022-04-01 03:27:00 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_42:PCStruct{gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_exomes (GetField gnomad_exomes (GetField __uid_42 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_42:PCStruct{gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 3.643ms, total 1m43.0s, tagged coverage 33.5 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.005ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 3.793ms, total 1m43.0s, tagged coverage 32.3 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.007ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 3.290ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.008ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 3.415ms, total 1m43.0s, tagged coverage 96.8 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.002ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_42:PCStruct{gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_exomes (GetField gnomad_exomes (GetField __uid_42 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_42:PCStruct{gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.055ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.040ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.078ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.219ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.041ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.792ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 1.457ms, total 1m43.0s, tagged coverage 84.1 2022-04-01 03:27:00 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_42:PCStruct{gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_exomes (GetField gnomad_exomes (GetField __uid_42 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_42:PCStruct{gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 3.625ms, total 1m43.0s, tagged coverage 33.8 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.004ms, total 1m43.0s 2022-04-01 03:27:00 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 3.736ms, total 1m43.0s, tagged coverage 33.0 2022-04-01 03:27:00 root: INFO: encoder cache hit 2022-04-01 03:27:00 MemoryStore: INFO: Block broadcast_23 stored as values in memory (estimated size 104.0 B, free 5.6 GB) 2022-04-01 03:27:00 MemoryStore: INFO: Block broadcast_23_piece0 stored as bytes in memory (estimated size 109.0 B, free 5.6 GB) 2022-04-01 03:27:00 BlockManagerInfo: INFO: Added broadcast_23_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 109.0 B, free: 5.6 GB) 2022-04-01 03:27:00 SparkContext: INFO: Created broadcast 23 from broadcast at SparkBackend.scala:233 2022-04-01 03:27:00 root: INFO: instruction count: 6: __C1745Compiled. 2022-04-01 03:27:00 root: INFO: instruction count: 446: __C1745Compiled.apply 2022-04-01 03:27:00 root: INFO: instruction count: 11: __C1745Compiled.__m1749addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 8: __C1745Compiled.__m1750addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 8: __C1745Compiled.__m1751addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 8: __C1745Compiled.__m1752addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 11: __C1745Compiled.__m1753addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 8: __C1745Compiled.__m1754addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 11: __C1745Compiled.__m1755addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 11: __C1745Compiled.__m1756addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 8: __C1745Compiled.__m1757addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 8: __C1745Compiled.__m1758addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 11: __C1745Compiled.__m1759addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 11: __C1745Compiled.__m1760addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 11: __C1745Compiled.__m1761addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 11: __C1745Compiled.__m1762addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 11: __C1745Compiled.__m1763addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 8: __C1745Compiled.__m1764addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 8: __C1745Compiled.__m1765addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 11: __C1745Compiled.__m1769addIRIntermediate 2022-04-01 03:27:00 root: INFO: instruction count: 14: __C1745Compiled.setPartitionIndex 2022-04-01 03:27:00 root: INFO: instruction count: 7: __C1745Compiled.addPartitionRegion 2022-04-01 03:27:00 root: INFO: instruction count: 25: __C1745Compiled.__m1773DECODE_r_struct_of_r_binaryEND_TO_r_tuple_of_r_stringEND 2022-04-01 03:27:00 root: INFO: instruction count: 11: __C1745Compiled.__m1774read_fields_group_0 2022-04-01 03:27:00 root: INFO: instruction count: 34: __C1745Compiled.__m1775INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:27:00 root: INFO: instruction count: 41: __C1745Compiled.addLiterals 2022-04-01 03:27:00 root: INFO: instruction count: 212: __C1745Compiled.applyregion0_7 2022-04-01 03:27:00 root: INFO: instruction count: 138: __C1745Compiled.applyregion64_71 2022-04-01 03:27:00 root: INFO: instruction count: 136: __C1745Compiled.applyregion72_79 2022-04-01 03:27:00 root: INFO: instruction count: 122: __C1745Compiled.applyregion32_39 2022-04-01 03:27:00 root: INFO: instruction count: 106: __C1745Compiled.applyregion96_103 2022-04-01 03:27:00 root: INFO: instruction count: 102: __C1745Compiled.applyregion80_87 2022-04-01 03:27:00 root: INFO: instruction count: 102: __C1745Compiled.applyregion16_23 2022-04-01 03:27:00 root: INFO: instruction count: 104: __C1745Compiled.applyregion128_135 2022-04-01 03:27:00 root: INFO: instruction count: 102: __C1745Compiled.applyregion104_111 2022-04-01 03:27:00 root: INFO: instruction count: 102: __C1745Compiled.applyregion56_63 2022-04-01 03:27:00 root: INFO: instruction count: 100: __C1745Compiled.applyregion40_47 2022-04-01 03:27:00 root: INFO: instruction count: 98: __C1745Compiled.applyregion8_15 2022-04-01 03:27:00 root: INFO: instruction count: 98: __C1745Compiled.applyregion24_31 2022-04-01 03:27:00 root: INFO: instruction count: 6: __C1777applySpills. 2022-04-01 03:27:01 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:01 root: INFO: decoder cache hit 2022-04-01 03:27:01 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/parts/part-0' for reading 2022-04-01 03:27:01 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:02 root: INFO: decoder cache miss (10 hits, 19 misses, 0.345 2022-04-01 03:27:02 root: INFO: instruction count: 6: __C1799etypeDecode. 2022-04-01 03:27:02 root: INFO: instruction count: 8: __C1799etypeDecode.apply 2022-04-01 03:27:02 root: INFO: instruction count: 47: __C1799etypeDecode.__m1800DECODE_r_struct_of_o_struct_of_r_binaryANDr_int32ENDANDo_array_of_o_binaryANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_struct_of_o_binaryENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryENDANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_int32ENDANDo_float32ANDo_float64END_TO_r_tuple_of_o_locusANDo_array_of_o_stringANDo_float32END 2022-04-01 03:27:02 root: INFO: instruction count: 283: __C1799etypeDecode.__m1801read_fields_group_0 2022-04-01 03:27:02 root: INFO: instruction count: 17: __C1799etypeDecode.__m1802INPLACE_DECODE_o_struct_of_r_binaryANDr_int32END_TO_o_tuple_of_r_binaryANDr_int32END 2022-04-01 03:27:02 root: INFO: instruction count: 18: __C1799etypeDecode.__m1803read_fields_group_0 2022-04-01 03:27:02 root: INFO: instruction count: 34: __C1799etypeDecode.__m1804INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:27:02 root: INFO: instruction count: 11: __C1799etypeDecode.__m1805INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:27:02 root: INFO: instruction count: 105: __C1799etypeDecode.__m1806INPLACE_DECODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:27:02 root: INFO: instruction count: 34: __C1799etypeDecode.__m1807INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:27:02 root: INFO: instruction count: 84: __C1799etypeDecode.__m1808SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64END 2022-04-01 03:27:02 root: INFO: instruction count: 6: __C1799etypeDecode.__m1809SKIP_o_int32 2022-04-01 03:27:02 root: INFO: instruction count: 6: __C1799etypeDecode.__m1810SKIP_o_float64 2022-04-01 03:27:02 root: INFO: instruction count: 39: __C1799etypeDecode.__m1811SKIP_o_struct_of_o_binaryEND 2022-04-01 03:27:02 root: INFO: instruction count: 10: __C1799etypeDecode.__m1812SKIP_o_binary 2022-04-01 03:27:02 root: INFO: instruction count: 39: __C1799etypeDecode.__m1813SKIP_o_struct_of_o_float32END 2022-04-01 03:27:02 root: INFO: instruction count: 6: __C1799etypeDecode.__m1814SKIP_o_float32 2022-04-01 03:27:02 root: INFO: instruction count: 39: __C1799etypeDecode.__m1815SKIP_o_struct_of_o_float64END 2022-04-01 03:27:02 root: INFO: instruction count: 144: __C1799etypeDecode.__m1816SKIP_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:27:02 root: INFO: instruction count: 99: __C1799etypeDecode.__m1817SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:27:02 root: INFO: instruction count: 39: __C1799etypeDecode.__m1818SKIP_o_struct_of_o_float64END 2022-04-01 03:27:02 root: INFO: instruction count: 39: __C1799etypeDecode.__m1819SKIP_o_struct_of_o_float32END 2022-04-01 03:27:02 root: INFO: instruction count: 129: __C1799etypeDecode.__m1820SKIP_o_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:27:02 root: INFO: instruction count: 129: __C1799etypeDecode.__m1821SKIP_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:27:02 root: INFO: instruction count: 39: __C1799etypeDecode.__m1822SKIP_o_struct_of_o_int32END 2022-04-01 03:27:02 root: INFO: instruction count: 11: __C1799etypeDecode.__m1823INPLACE_DECODE_o_float32_TO_o_float32 2022-04-01 03:27:08 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:09 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:09 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:10 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:10 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:10 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:10 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:11 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:12 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:12 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:13 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:13 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:13 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:14 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:14 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:15 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:15 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:16 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:16 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:17 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:17 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:17 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:17 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:18 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.016ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_43:PCStruct{gnomad_genome_coverage:PFloat32}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_genome_coverage (GetField gnomad_genome_coverage (GetField __uid_43 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_43:PCStruct{gnomad_genome_coverage:PFloat32}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.229ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.037ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.079ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.168ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.031ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.568ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 1.284ms, total 2m1.5s, tagged coverage 86.5 2022-04-01 03:27:18 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_43:PCStruct{gnomad_genome_coverage:PFloat32}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_genome_coverage (GetField gnomad_genome_coverage (GetField __uid_43 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_43:PCStruct{gnomad_genome_coverage:PFloat32}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 2.865ms, total 2m1.5s, tagged coverage 38.8 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.004ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 3.021ms, total 2m1.5s, tagged coverage 37.5 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.006ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.012ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.004ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.068ms, total 2m1.5s, tagged coverage 33.0 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.001ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_43:PCStruct{gnomad_genome_coverage:PFloat32}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_genome_coverage (GetField gnomad_genome_coverage (GetField __uid_43 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_43:PCStruct{gnomad_genome_coverage:PFloat32}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.046ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.030ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.067ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.132ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.027ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.494ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 0.939ms, total 2m1.5s, tagged coverage 84.6 2022-04-01 03:27:18 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_43:PCStruct{gnomad_genome_coverage:PFloat32}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_genome_coverage (GetField gnomad_genome_coverage (GetField __uid_43 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_43:PCStruct{gnomad_genome_coverage:PFloat32}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 2.491ms, total 2m1.5s, tagged coverage 31.9 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.004ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 2.626ms, total 2m1.5s, tagged coverage 30.5 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.006ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 2.317ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.006ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 2.412ms, total 2m1.5s, tagged coverage 96.5 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.001ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_43:PCStruct{gnomad_genome_coverage:PFloat32}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_genome_coverage (GetField gnomad_genome_coverage (GetField __uid_43 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_43:PCStruct{gnomad_genome_coverage:PFloat32}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.042ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.032ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.059ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.129ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.024ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.489ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 0.919ms, total 2m1.5s, tagged coverage 84.3 2022-04-01 03:27:18 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 9: (Coalesce (InsertFields (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes `the entries! [877f12a8827e18f61222c6c8c5fb04a8]`) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_43:PCStruct{gnomad_genome_coverage:PFloat32}} 1)) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "the entries! [877f12a8827e18f61222c6c8c5fb04a8]") (gnomad_genome_coverage (GetField gnomad_genome_coverage (GetField __uid_43 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_43:PCStruct{gnomad_genome_coverage:PFloat32}} 1))))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 2.377ms, total 2m1.5s, tagged coverage 32.6 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.003ms, total 2m1.5s 2022-04-01 03:27:18 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 2.466ms, total 2m1.5s, tagged coverage 31.6 2022-04-01 03:27:18 root: INFO: encoder cache hit 2022-04-01 03:27:18 MemoryStore: INFO: Block broadcast_24 stored as values in memory (estimated size 104.0 B, free 5.6 GB) 2022-04-01 03:27:18 MemoryStore: INFO: Block broadcast_24_piece0 stored as bytes in memory (estimated size 109.0 B, free 5.6 GB) 2022-04-01 03:27:18 BlockManagerInfo: INFO: Added broadcast_24_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 109.0 B, free: 5.6 GB) 2022-04-01 03:27:18 SparkContext: INFO: Created broadcast 24 from broadcast at SparkBackend.scala:233 2022-04-01 03:27:18 root: INFO: instruction count: 6: __C1824Compiled. 2022-04-01 03:27:18 root: INFO: instruction count: 434: __C1824Compiled.apply 2022-04-01 03:27:18 root: INFO: instruction count: 11: __C1824Compiled.__m1828addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 8: __C1824Compiled.__m1829addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 8: __C1824Compiled.__m1830addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 8: __C1824Compiled.__m1831addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 11: __C1824Compiled.__m1832addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 8: __C1824Compiled.__m1833addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 11: __C1824Compiled.__m1834addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 11: __C1824Compiled.__m1835addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 8: __C1824Compiled.__m1836addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 8: __C1824Compiled.__m1837addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 11: __C1824Compiled.__m1838addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 11: __C1824Compiled.__m1839addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 11: __C1824Compiled.__m1840addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 11: __C1824Compiled.__m1841addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 11: __C1824Compiled.__m1842addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 8: __C1824Compiled.__m1843addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 11: __C1824Compiled.__m1844addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 8: __C1824Compiled.__m1845addIRIntermediate 2022-04-01 03:27:18 root: INFO: instruction count: 14: __C1824Compiled.setPartitionIndex 2022-04-01 03:27:18 root: INFO: instruction count: 7: __C1824Compiled.addPartitionRegion 2022-04-01 03:27:18 root: INFO: instruction count: 25: __C1824Compiled.__m1852DECODE_r_struct_of_r_binaryEND_TO_r_tuple_of_r_stringEND 2022-04-01 03:27:18 root: INFO: instruction count: 11: __C1824Compiled.__m1853read_fields_group_0 2022-04-01 03:27:18 root: INFO: instruction count: 34: __C1824Compiled.__m1854INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:27:18 root: INFO: instruction count: 41: __C1824Compiled.addLiterals 2022-04-01 03:27:18 root: INFO: instruction count: 212: __C1824Compiled.applyregion0_7 2022-04-01 03:27:18 root: INFO: instruction count: 134: __C1824Compiled.applyregion64_71 2022-04-01 03:27:18 root: INFO: instruction count: 122: __C1824Compiled.applyregion104_111 2022-04-01 03:27:18 root: INFO: instruction count: 122: __C1824Compiled.applyregion72_79 2022-04-01 03:27:18 root: INFO: instruction count: 122: __C1824Compiled.applyregion32_39 2022-04-01 03:27:18 root: INFO: instruction count: 102: __C1824Compiled.applyregion88_95 2022-04-01 03:27:18 root: INFO: instruction count: 102: __C1824Compiled.applyregion16_23 2022-04-01 03:27:18 root: INFO: instruction count: 102: __C1824Compiled.applyregion128_135 2022-04-01 03:27:18 root: INFO: instruction count: 102: __C1824Compiled.applyregion56_63 2022-04-01 03:27:18 root: INFO: instruction count: 100: __C1824Compiled.applyregion112_119 2022-04-01 03:27:18 root: INFO: instruction count: 100: __C1824Compiled.applyregion40_47 2022-04-01 03:27:18 root: INFO: instruction count: 98: __C1824Compiled.applyregion80_87 2022-04-01 03:27:18 root: INFO: instruction count: 98: __C1824Compiled.applyregion8_15 2022-04-01 03:27:18 root: INFO: instruction count: 98: __C1824Compiled.applyregion96_103 2022-04-01 03:27:18 root: INFO: instruction count: 6: __C1856applySpills. 2022-04-01 03:27:19 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:19 root: INFO: decoder cache hit 2022-04-01 03:27:19 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/parts/part-0' for reading 2022-04-01 03:27:20 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:20 root: INFO: decoder cache miss (11 hits, 20 misses, 0.355 2022-04-01 03:27:20 root: INFO: instruction count: 6: __C1878etypeDecode. 2022-04-01 03:27:20 root: INFO: instruction count: 8: __C1878etypeDecode.apply 2022-04-01 03:27:20 root: INFO: instruction count: 47: __C1878etypeDecode.__m1879DECODE_r_struct_of_o_struct_of_r_binaryANDr_int32ENDANDo_array_of_o_binaryANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_struct_of_o_binaryENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryENDANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_int32ENDANDo_float32ANDo_float64END_TO_r_tuple_of_o_locusANDo_array_of_o_stringANDo_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDEND 2022-04-01 03:27:20 root: INFO: instruction count: 283: __C1878etypeDecode.__m1880read_fields_group_0 2022-04-01 03:27:20 root: INFO: instruction count: 17: __C1878etypeDecode.__m1881INPLACE_DECODE_o_struct_of_r_binaryANDr_int32END_TO_o_tuple_of_r_binaryANDr_int32END 2022-04-01 03:27:20 root: INFO: instruction count: 18: __C1878etypeDecode.__m1882read_fields_group_0 2022-04-01 03:27:20 root: INFO: instruction count: 34: __C1878etypeDecode.__m1883INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:27:20 root: INFO: instruction count: 11: __C1878etypeDecode.__m1884INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:27:20 root: INFO: instruction count: 105: __C1878etypeDecode.__m1885INPLACE_DECODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:27:20 root: INFO: instruction count: 34: __C1878etypeDecode.__m1886INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:27:20 root: INFO: instruction count: 84: __C1878etypeDecode.__m1887SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64END 2022-04-01 03:27:20 root: INFO: instruction count: 6: __C1878etypeDecode.__m1888SKIP_o_int32 2022-04-01 03:27:20 root: INFO: instruction count: 6: __C1878etypeDecode.__m1889SKIP_o_float64 2022-04-01 03:27:20 root: INFO: instruction count: 39: __C1878etypeDecode.__m1890SKIP_o_struct_of_o_binaryEND 2022-04-01 03:27:20 root: INFO: instruction count: 10: __C1878etypeDecode.__m1891SKIP_o_binary 2022-04-01 03:27:20 root: INFO: instruction count: 39: __C1878etypeDecode.__m1892SKIP_o_struct_of_o_float32END 2022-04-01 03:27:20 root: INFO: instruction count: 6: __C1878etypeDecode.__m1893SKIP_o_float32 2022-04-01 03:27:20 root: INFO: instruction count: 39: __C1878etypeDecode.__m1894SKIP_o_struct_of_o_float64END 2022-04-01 03:27:20 root: INFO: instruction count: 144: __C1878etypeDecode.__m1895SKIP_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:27:20 root: INFO: instruction count: 99: __C1878etypeDecode.__m1896SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:27:20 root: INFO: instruction count: 39: __C1878etypeDecode.__m1897SKIP_o_struct_of_o_float64END 2022-04-01 03:27:20 root: INFO: instruction count: 39: __C1878etypeDecode.__m1898SKIP_o_struct_of_o_float32END 2022-04-01 03:27:20 root: INFO: instruction count: 129: __C1878etypeDecode.__m1899SKIP_o_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:27:20 root: INFO: instruction count: 30: __C1878etypeDecode.__m1900INPLACE_DECODE_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END_TO_o_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:27:20 root: INFO: instruction count: 200: __C1878etypeDecode.__m1901read_fields_group_0 2022-04-01 03:27:20 root: INFO: instruction count: 11: __C1878etypeDecode.__m1902INPLACE_DECODE_o_float64_TO_o_float64 2022-04-01 03:27:20 root: INFO: instruction count: 11: __C1878etypeDecode.__m1903INPLACE_DECODE_o_int32_TO_o_int32 2022-04-01 03:27:20 root: INFO: instruction count: 129: __C1878etypeDecode.__m1904SKIP_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:27:20 root: INFO: instruction count: 39: __C1878etypeDecode.__m1905SKIP_o_struct_of_o_int32END 2022-04-01 03:27:26 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:28 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:28 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:29 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:29 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:29 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:30 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:30 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:30 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:31 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:31 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:32 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:32 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:32 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:32 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:33 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:33 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:40 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:40 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:41 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:41 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:42 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:42 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:42 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:42 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:43 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.034ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 36: (Coalesce (InsertFields (Let __iruid_4354 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)) (InsertFields (Ref __iruid_4354) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript") (gnomad_genomes (GetField gnomad_genomes (GetField __uid_44 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)))) (mainTranscript (If (ApplyComparisonOp EQ (ArrayLen (GetField sortedTranscriptConsequences (Ref __iruid_4354))) (I32 0)) (Literal Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String} ) (Let __iruid_4355 (ApplyIR indexArray () Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32} (GetField sortedTranscriptConsequences (Ref __iruid_4354)) (I32 0) (Str " File \"/h...")) (InsertFields (SelectFields (biotype canonical category cdna_start cdna_end codons gene_id gene_symbol hgvs hgvsc major_consequence major_consequence_rank transcript_id amino_acids domains hgvsp lof lof_flags lof_filter lof_info polyphen_prediction protein_id sift_prediction) (Ref __iruid_4355)) ("biotype" "canonical" "category" "cdna_start" "cdna_end" "codons" "gene_id" "gene_symbol" "hgvs" "hgvsc" "major_consequence" "major_consequence_rank" "transcript_id" "amino_acids" "domains" "hgvsp" "lof" "lof_flags" "lof_filter" "lof_info" "polyphen_prediction" "protein_id" "sift_prediction") (domains (Apply mkString () String (ToSet (ToStream False (GetField domains (Ref __iruid_4355)))) (Str ","))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.480ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.091ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.237ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.536ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.094ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.313ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.151ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.103ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.347ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.672ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.133ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.577ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.143ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.073ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.228ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.444ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.077ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.776ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 11.115ms, total 2m26.5s, tagged coverage 94.3 2022-04-01 03:27:43 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 36: (Coalesce (InsertFields (Let __iruid_6233 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)) (InsertFields (Ref __iruid_6233) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript") (gnomad_genomes (GetField gnomad_genomes (GetField __uid_44 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)))) (mainTranscript (If (ApplyComparisonOp EQ (ArrayLen (GetField sortedTranscriptConsequences (Ref __iruid_6233))) (I32 0)) (Literal Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String} ) (Let __iruid_6234 (ApplyIR indexArray () Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32} (GetField sortedTranscriptConsequences (Ref __iruid_6233)) (I32 0) (Str " File \"/h...")) (InsertFields (SelectFields (biotype canonical category cdna_start cdna_end codons gene_id gene_symbol hgvs hgvsc major_consequence major_consequence_rank transcript_id amino_acids domains hgvsp lof lof_flags lof_filter lof_info polyphen_prediction protein_id sift_prediction) (Ref __iruid_6234)) ("biotype" "canonical" "category" "cdna_start" "cdna_end" "codons" "gene_id" "gene_symbol" "hgvs" "hgvsc" "major_consequence" "major_consequence_rank" "transcript_id" "amino_acids" "domains" "hgvsp" "lof" "lof_flags" "lof_filter" "lof_info" "polyphen_prediction" "protein_id" "sift_prediction") (domains (Apply mkString () String (ToSet (ToStream False (GetField domains (Ref __iruid_6234)))) (Str ","))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 13.723ms, total 2m26.5s, tagged coverage 76.3 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.008ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 13.916ms, total 2m26.5s, tagged coverage 75.6 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.019ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.090ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.022ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.195ms, total 2m26.5s, tagged coverage 67.7 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.005ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 50: (Coalesce (InsertFields (Let __iruid_6233 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)) (InsertFields (Ref __iruid_6233) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript") (gnomad_genomes (GetField gnomad_genomes (GetField __uid_44 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)))) (mainTranscript (If (ApplyComparisonOp EQ (ArrayLen (GetField sortedTranscriptConsequences (Ref __iruid_6233))) (I32 0)) (Literal Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String} ) (Let __iruid_6234 (Let __iruid_6241 (GetField sortedTranscriptConsequences (Ref __iruid_6233)) (Let __iruid_6242 (I32 0) (Let __iruid_6243 (Str " File \"/h...") (ArrayRef (Ref __iruid_6241) (If (ApplyComparisonOp LT (Ref __iruid_6242) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_6241)) (Ref __iruid_6242)) (Ref __iruid_6242)) (Ref __iruid_6243))))) (InsertFields (SelectFields (biotype canonical category cdna_start cdna_end codons gene_id gene_symbol hgvs hgvsc major_consequence major_consequence_rank transcript_id amino_acids domains hgvsp lof lof_flags lof_filter lof_info polyphen_prediction protein_id sift_prediction) (Ref __iruid_6234)) ("biotype" "canonical" "category" "cdna_start" "cdna_end" "codons" "gene_id" "gene_symbol" "hgvs" "hgvsc" "major_consequence" "major_consequence_rank" "transcript_id" "amino_acids" "domains" "hgvsp" "lof" "lof_flags" "lof_filter" "lof_info" "polyphen_prediction" "protein_id" "sift_prediction") (domains (Apply mkString () String (ToSet (ToStream False (GetField domains (Ref __iruid_6234)))) (Str ","))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.085ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.086ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.471ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.581ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.106ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.959ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.363ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.074ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.205ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.471ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.076ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.803ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.094ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.071ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.145ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.388ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.074ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.733ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 9.318ms, total 2m26.5s, tagged coverage 94.3 2022-04-01 03:27:43 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 36: (Coalesce (InsertFields (Let __iruid_6252 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)) (InsertFields (Ref __iruid_6252) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript") (gnomad_genomes (GetField gnomad_genomes (GetField __uid_44 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)))) (mainTranscript (If (ApplyComparisonOp EQ (ArrayLen (GetField sortedTranscriptConsequences (Ref __iruid_6252))) (I32 0)) (Literal Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String} ) (Let __iruid_6253 (ArrayRef (GetField sortedTranscriptConsequences (Ref __iruid_6252)) (I32 0) (Str " File \"/h...")) (InsertFields (SelectFields (biotype canonical category cdna_start cdna_end codons gene_id gene_symbol hgvs hgvsc major_consequence major_consequence_rank transcript_id amino_acids domains hgvsp lof lof_flags lof_filter lof_info polyphen_prediction protein_id sift_prediction) (Ref __iruid_6253)) ("biotype" "canonical" "category" "cdna_start" "cdna_end" "codons" "gene_id" "gene_symbol" "hgvs" "hgvsc" "major_consequence" "major_consequence_rank" "transcript_id" "amino_acids" "domains" "hgvsp" "lof" "lof_flags" "lof_filter" "lof_info" "polyphen_prediction" "protein_id" "sift_prediction") (domains (Apply mkString () String (ToSet (ToStream False (GetField domains (Ref __iruid_6253)))) (Str ","))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 11.792ms, total 2m26.5s, tagged coverage 74.5 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.010ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 11.918ms, total 2m26.5s, tagged coverage 73.8 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.016ms, total 2m26.5s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 7.228ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.011ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 7.363ms, total 2m26.6s, tagged coverage 98.5 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.003ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 36: (Coalesce (InsertFields (Let __iruid_6252 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)) (InsertFields (Ref __iruid_6252) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript") (gnomad_genomes (GetField gnomad_genomes (GetField __uid_44 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)))) (mainTranscript (If (ApplyComparisonOp EQ (ArrayLen (GetField sortedTranscriptConsequences (Ref __iruid_6252))) (I32 0)) (Literal Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String} ) (Let __iruid_6253 (ArrayRef (GetField sortedTranscriptConsequences (Ref __iruid_6252)) (I32 0) (Str " File \"/h...")) (InsertFields (SelectFields (biotype canonical category cdna_start cdna_end codons gene_id gene_symbol hgvs hgvsc major_consequence major_consequence_rank transcript_id amino_acids domains hgvsp lof lof_flags lof_filter lof_info polyphen_prediction protein_id sift_prediction) (Ref __iruid_6253)) ("biotype" "canonical" "category" "cdna_start" "cdna_end" "codons" "gene_id" "gene_symbol" "hgvs" "hgvsc" "major_consequence" "major_consequence_rank" "transcript_id" "amino_acids" "domains" "hgvsp" "lof" "lof_flags" "lof_filter" "lof_info" "polyphen_prediction" "protein_id" "sift_prediction") (domains (Apply mkString () String (ToSet (ToStream False (GetField domains (Ref __iruid_6253)))) (Str ","))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.068ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.107ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.224ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.609ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.086ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.730ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.095ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.069ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.146ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.432ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.075ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.713ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.090ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.067ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.142ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.408ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.075ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.612ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 9.401ms, total 2m26.6s, tagged coverage 93.0 2022-04-01 03:27:43 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 36: (Coalesce (InsertFields (Let __iruid_6258 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)) (InsertFields (Ref __iruid_6258) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript") (gnomad_genomes (GetField gnomad_genomes (GetField __uid_44 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)))) (mainTranscript (If (ApplyComparisonOp EQ (ArrayLen (GetField sortedTranscriptConsequences (Ref __iruid_6258))) (I32 0)) (Literal Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String} ) (Let __iruid_6259 (ArrayRef (GetField sortedTranscriptConsequences (Ref __iruid_6258)) (I32 0) (Str " File \"/h...")) (InsertFields (SelectFields (biotype canonical category cdna_start cdna_end codons gene_id gene_symbol hgvs hgvsc major_consequence major_consequence_rank transcript_id amino_acids domains hgvsp lof lof_flags lof_filter lof_info polyphen_prediction protein_id sift_prediction) (Ref __iruid_6259)) ("biotype" "canonical" "category" "cdna_start" "cdna_end" "codons" "gene_id" "gene_symbol" "hgvs" "hgvsc" "major_consequence" "major_consequence_rank" "transcript_id" "amino_acids" "domains" "hgvsp" "lof" "lof_flags" "lof_filter" "lof_info" "polyphen_prediction" "protein_id" "sift_prediction") (domains (Apply mkString () String (ToSet (ToStream False (GetField domains (Ref __iruid_6259)))) (Str ","))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_44:PCStruct{gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 12.373ms, total 2m26.6s, tagged coverage 70.7 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.009ms, total 2m26.6s 2022-04-01 03:27:43 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 12.483ms, total 2m26.6s, tagged coverage 70.2 2022-04-01 03:27:43 root: INFO: encoder cache miss (12 hits, 10 misses, 0.545) 2022-04-01 03:27:43 root: INFO: instruction count: 6: __C1981etypeEncode. 2022-04-01 03:27:43 root: INFO: instruction count: 8: __C1981etypeEncode.apply 2022-04-01 03:27:43 root: INFO: instruction count: 32: __C1981etypeEncode.__m1982ENCODE_r_tuple_of_r_stringANDr_stringANDr_tuple_of_o_stringANDo_int32ANDo_stringANDo_int32ANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDEND_TO_r_struct_of_r_binaryANDr_binaryANDr_struct_of_o_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryENDEND 2022-04-01 03:27:43 root: INFO: instruction count: 19: __C1981etypeEncode.__m1983ENCODE_r_binary_TO_r_binary 2022-04-01 03:27:43 root: INFO: instruction count: 505: __C1981etypeEncode.__m1984ENCODE_r_tuple_of_o_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND_TO_r_struct_of_o_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:27:43 root: INFO: instruction count: 19: __C1981etypeEncode.__m1985ENCODE_o_binary_TO_o_binary 2022-04-01 03:27:43 root: INFO: instruction count: 7: __C1981etypeEncode.__m1986ENCODE_o_int32_TO_o_int32 2022-04-01 03:27:43 MemoryStore: INFO: Block broadcast_25 stored as values in memory (estimated size 112.0 B, free 5.6 GB) 2022-04-01 03:27:43 MemoryStore: INFO: Block broadcast_25_piece0 stored as bytes in memory (estimated size 117.0 B, free 5.6 GB) 2022-04-01 03:27:43 BlockManagerInfo: INFO: Added broadcast_25_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 117.0 B, free: 5.6 GB) 2022-04-01 03:27:43 SparkContext: INFO: Created broadcast 25 from broadcast at SparkBackend.scala:233 2022-04-01 03:27:44 root: INFO: instruction count: 6: __C1906Compiled. 2022-04-01 03:27:44 root: INFO: instruction count: 456: __C1906Compiled.apply 2022-04-01 03:27:44 root: INFO: instruction count: 11: __C1906Compiled.__m1912addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 8: __C1906Compiled.__m1913addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 8: __C1906Compiled.__m1914addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 8: __C1906Compiled.__m1915addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 11: __C1906Compiled.__m1916addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 8: __C1906Compiled.__m1917addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 11: __C1906Compiled.__m1918addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 11: __C1906Compiled.__m1919addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 8: __C1906Compiled.__m1920addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 8: __C1906Compiled.__m1921addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 11: __C1906Compiled.__m1922addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 11: __C1906Compiled.__m1923addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 11: __C1906Compiled.__m1924addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 11: __C1906Compiled.__m1925addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 11: __C1906Compiled.__m1926addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 8: __C1906Compiled.__m1927addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 11: __C1906Compiled.__m1928addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 38: __C1906Compiled.__m1932cord 2022-04-01 03:27:44 root: INFO: instruction count: 81: __C1906Compiled.__m1942mkString 2022-04-01 03:27:44 root: INFO: instruction count: 15: __C1906Compiled.__m1945setup_null 2022-04-01 03:27:44 root: INFO: instruction count: 15: __C1906Compiled.__m1950setup_jab 2022-04-01 03:27:44 root: INFO: instruction count: 66: __C1906Compiled.__m1951discardNext 2022-04-01 03:27:44 root: INFO: instruction count: 135: __C1906Compiled.__m1952cord 2022-04-01 03:27:44 root: INFO: instruction count: 11: __C1906Compiled.__m1965addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 8: __C1906Compiled.__m1969addIRIntermediate 2022-04-01 03:27:44 root: INFO: instruction count: 14: __C1906Compiled.setPartitionIndex 2022-04-01 03:27:44 root: INFO: instruction count: 7: __C1906Compiled.addPartitionRegion 2022-04-01 03:27:44 root: INFO: instruction count: 25: __C1906Compiled.__m1973DECODE_r_struct_of_r_binaryANDr_binaryANDr_struct_of_o_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryENDEND_TO_r_tuple_of_r_stringANDr_stringANDr_tuple_of_o_stringANDo_int32ANDo_stringANDo_int32ANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDEND 2022-04-01 03:27:44 root: INFO: instruction count: 25: __C1906Compiled.__m1974read_fields_group_0 2022-04-01 03:27:44 root: INFO: instruction count: 34: __C1906Compiled.__m1975INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:27:44 root: INFO: instruction count: 48: __C1906Compiled.__m1976INPLACE_DECODE_r_struct_of_o_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND_TO_r_tuple_of_o_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:27:44 root: INFO: instruction count: 450: __C1906Compiled.__m1977read_fields_group_0 2022-04-01 03:27:44 root: INFO: instruction count: 34: __C1906Compiled.__m1978INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:27:44 root: INFO: instruction count: 11: __C1906Compiled.__m1979INPLACE_DECODE_o_int32_TO_o_int32 2022-04-01 03:27:44 root: INFO: instruction count: 55: __C1906Compiled.addLiterals 2022-04-01 03:27:44 root: INFO: instruction count: 304: __C1906Compiled.applyregion328_377 2022-04-01 03:27:44 root: INFO: instruction count: 135: __C1906Compiled.applyregion168_175 2022-04-01 03:27:44 root: INFO: instruction count: 140: __C1906Compiled.applyregion160_167 2022-04-01 03:27:44 root: INFO: instruction count: 97: __C1906Compiled.applyregion385_392 2022-04-01 03:27:44 root: INFO: instruction count: 87: __C1906Compiled.applyregion378_380 2022-04-01 03:27:44 root: INFO: instruction count: 86: __C1906Compiled.applyregion401_408 2022-04-01 03:27:44 root: INFO: instruction count: 86: __C1906Compiled.applyregion393_400 2022-04-01 03:27:44 root: INFO: instruction count: 86: __C1906Compiled.applyregion296_303 2022-04-01 03:27:44 root: INFO: instruction count: 86: __C1906Compiled.applyregion288_295 2022-04-01 03:27:44 root: INFO: instruction count: 86: __C1906Compiled.applyregion280_287 2022-04-01 03:27:44 root: INFO: instruction count: 86: __C1906Compiled.applyregion248_255 2022-04-01 03:27:44 root: INFO: instruction count: 86: __C1906Compiled.applyregion240_247 2022-04-01 03:27:44 root: INFO: instruction count: 86: __C1906Compiled.applyregion232_239 2022-04-01 03:27:44 root: INFO: instruction count: 86: __C1906Compiled.applyregion224_231 2022-04-01 03:27:44 root: INFO: instruction count: 86: __C1906Compiled.applyregion216_223 2022-04-01 03:27:44 root: INFO: instruction count: 86: __C1906Compiled.applyregion200_207 2022-04-01 03:27:44 root: INFO: instruction count: 86: __C1906Compiled.applyregion192_199 2022-04-01 03:27:44 root: INFO: instruction count: 84: __C1906Compiled.applyregion304_311 2022-04-01 03:27:44 root: INFO: instruction count: 84: __C1906Compiled.applyregion264_271 2022-04-01 03:27:44 root: INFO: instruction count: 84: __C1906Compiled.applyregion208_215 2022-04-01 03:27:44 root: INFO: instruction count: 84: __C1906Compiled.applyregion184_191 2022-04-01 03:27:44 root: INFO: instruction count: 84: __C1906Compiled.applyregion176_183 2022-04-01 03:27:44 root: INFO: instruction count: 82: __C1906Compiled.applyregion272_279 2022-04-01 03:27:44 root: INFO: instruction count: 84: __C1906Compiled.applyregion256_263 2022-04-01 03:27:44 root: INFO: instruction count: 95: __C1906Compiled.applyregion434_439 2022-04-01 03:27:44 root: INFO: instruction count: 77: __C1906Compiled.applyregion409_416 2022-04-01 03:27:44 root: INFO: instruction count: 72: __C1906Compiled.applyregion318_323 2022-04-01 03:27:44 root: INFO: instruction count: 70: __C1906Compiled.applyregion494_499 2022-04-01 03:27:44 root: INFO: instruction count: 70: __C1906Compiled.applyregion488_493 2022-04-01 03:27:44 root: INFO: instruction count: 70: __C1906Compiled.applyregion482_487 2022-04-01 03:27:44 root: INFO: instruction count: 70: __C1906Compiled.applyregion476_481 2022-04-01 03:27:44 root: INFO: instruction count: 70: __C1906Compiled.applyregion470_475 2022-04-01 03:27:44 root: INFO: instruction count: 70: __C1906Compiled.applyregion458_463 2022-04-01 03:27:44 root: INFO: instruction count: 70: __C1906Compiled.applyregion452_457 2022-04-01 03:27:44 root: INFO: instruction count: 67: __C1906Compiled.applyregion464_469 2022-04-01 03:27:44 root: INFO: instruction count: 653: __C1906Compiled.applyregion157_503 2022-04-01 03:27:44 root: INFO: instruction count: 188: __C1906Compiled.applyregion0_7 2022-04-01 03:27:44 root: INFO: instruction count: 167: __C1906Compiled.applyregion72_79 2022-04-01 03:27:44 root: INFO: instruction count: 136: __C1906Compiled.applyregion512_519 2022-04-01 03:27:44 root: INFO: instruction count: 136: __C1906Compiled.applyregion80_87 2022-04-01 03:27:44 root: INFO: instruction count: 122: __C1906Compiled.applyregion32_39 2022-04-01 03:27:44 root: INFO: instruction count: 114: __C1906Compiled.applyregion504_511 2022-04-01 03:27:44 root: INFO: instruction count: 106: __C1906Compiled.applyregion536_543 2022-04-01 03:27:44 root: INFO: instruction count: 106: __C1906Compiled.applyregion104_111 2022-04-01 03:27:44 root: INFO: instruction count: 102: __C1906Compiled.applyregion520_527 2022-04-01 03:27:44 root: INFO: instruction count: 102: __C1906Compiled.applyregion88_95 2022-04-01 03:27:44 root: INFO: instruction count: 102: __C1906Compiled.applyregion16_23 2022-04-01 03:27:44 root: INFO: instruction count: 102: __C1906Compiled.applyregion544_551 2022-04-01 03:27:44 root: INFO: instruction count: 102: __C1906Compiled.applyregion112_119 2022-04-01 03:27:44 root: INFO: instruction count: 102: __C1906Compiled.applyregion56_63 2022-04-01 03:27:44 root: INFO: instruction count: 100: __C1906Compiled.applyregion568_575 2022-04-01 03:27:44 root: INFO: instruction count: 100: __C1906Compiled.applyregion136_143 2022-04-01 03:27:44 root: INFO: instruction count: 100: __C1906Compiled.applyregion40_47 2022-04-01 03:27:44 root: INFO: instruction count: 98: __C1906Compiled.applyregion8_15 2022-04-01 03:27:44 root: INFO: instruction count: 98: __C1906Compiled.applyregion24_31 2022-04-01 03:27:44 root: INFO: instruction count: 96: __C1906Compiled.applyregion552_559 2022-04-01 03:27:44 root: INFO: instruction count: 96: __C1906Compiled.applyregion528_535 2022-04-01 03:27:44 root: INFO: instruction count: 96: __C1906Compiled.applyregion120_127 2022-04-01 03:27:44 root: INFO: instruction count: 96: __C1906Compiled.applyregion96_103 2022-04-01 03:27:44 root: INFO: instruction count: 91: __C1906Compiled.applyregion584_591 2022-04-01 03:27:44 root: INFO: instruction count: 82: __C1906Compiled.applyregion560_567 2022-04-01 03:27:44 root: INFO: instruction count: 84: __C1906Compiled.applyregion144_151 2022-04-01 03:27:44 root: INFO: instruction count: 81: __C1906Compiled.__m1977read_fields_group_0region0_7 2022-04-01 03:27:44 root: INFO: instruction count: 76: __C1906Compiled.__m1977read_fields_group_0region80_87 2022-04-01 03:27:44 root: INFO: instruction count: 76: __C1906Compiled.__m1977read_fields_group_0region72_79 2022-04-01 03:27:44 root: INFO: instruction count: 76: __C1906Compiled.__m1977read_fields_group_0region64_71 2022-04-01 03:27:44 root: INFO: instruction count: 6: __C1987applySpills. 2022-04-01 03:27:44 root: INFO: instruction count: 6: __C2068__m1977read_fields_group_0Spills. 2022-04-01 03:27:44 root: INFO: instruction count: 6: __C1953sort_compare. 2022-04-01 03:27:44 root: INFO: instruction count: 20: __C1953sort_compare.apply 2022-04-01 03:27:44 root: INFO: instruction count: 21: __C1953sort_compare.apply 2022-04-01 03:27:44 root: INFO: instruction count: 61: __C1953sort_compare.__m1955sort 2022-04-01 03:27:44 root: INFO: instruction count: 26: __C1953sort_compare.__m1956cord 2022-04-01 03:27:44 root: INFO: instruction count: 142: __C1953sort_compare.__m1957cord 2022-04-01 03:27:45 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:45 root: INFO: decoder cache hit 2022-04-01 03:27:45 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/parts/part-0' for reading 2022-04-01 03:27:45 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:46 root: INFO: decoder cache miss (12 hits, 21 misses, 0.364 2022-04-01 03:27:46 root: INFO: instruction count: 6: __C2078etypeDecode. 2022-04-01 03:27:46 root: INFO: instruction count: 8: __C2078etypeDecode.apply 2022-04-01 03:27:46 root: INFO: instruction count: 47: __C2078etypeDecode.__m2079DECODE_r_struct_of_o_struct_of_r_binaryANDr_int32ENDANDo_array_of_o_binaryANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_struct_of_o_binaryENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryENDANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_int32ENDANDo_float32ANDo_float64END_TO_r_tuple_of_o_locusANDo_array_of_o_stringANDo_tuple_of_o_stringENDEND 2022-04-01 03:27:46 root: INFO: instruction count: 283: __C2078etypeDecode.__m2080read_fields_group_0 2022-04-01 03:27:46 root: INFO: instruction count: 17: __C2078etypeDecode.__m2081INPLACE_DECODE_o_struct_of_r_binaryANDr_int32END_TO_o_tuple_of_r_binaryANDr_int32END 2022-04-01 03:27:46 root: INFO: instruction count: 18: __C2078etypeDecode.__m2082read_fields_group_0 2022-04-01 03:27:46 root: INFO: instruction count: 34: __C2078etypeDecode.__m2083INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:27:46 root: INFO: instruction count: 11: __C2078etypeDecode.__m2084INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:27:46 root: INFO: instruction count: 105: __C2078etypeDecode.__m2085INPLACE_DECODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:27:46 root: INFO: instruction count: 34: __C2078etypeDecode.__m2086INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:27:46 root: INFO: instruction count: 84: __C2078etypeDecode.__m2087SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64END 2022-04-01 03:27:46 root: INFO: instruction count: 6: __C2078etypeDecode.__m2088SKIP_o_int32 2022-04-01 03:27:46 root: INFO: instruction count: 6: __C2078etypeDecode.__m2089SKIP_o_float64 2022-04-01 03:27:46 root: INFO: instruction count: 30: __C2078etypeDecode.__m2090INPLACE_DECODE_o_struct_of_o_binaryEND_TO_o_tuple_of_o_binaryEND 2022-04-01 03:27:46 root: INFO: instruction count: 32: __C2078etypeDecode.__m2091read_fields_group_0 2022-04-01 03:27:46 root: INFO: instruction count: 39: __C2078etypeDecode.__m2092SKIP_o_struct_of_o_float32END 2022-04-01 03:27:46 root: INFO: instruction count: 6: __C2078etypeDecode.__m2093SKIP_o_float32 2022-04-01 03:27:46 root: INFO: instruction count: 39: __C2078etypeDecode.__m2094SKIP_o_struct_of_o_float64END 2022-04-01 03:27:46 root: INFO: instruction count: 144: __C2078etypeDecode.__m2095SKIP_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:27:46 root: INFO: instruction count: 10: __C2078etypeDecode.__m2096SKIP_o_binary 2022-04-01 03:27:46 root: INFO: instruction count: 99: __C2078etypeDecode.__m2097SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:27:46 root: INFO: instruction count: 39: __C2078etypeDecode.__m2098SKIP_o_struct_of_o_float64END 2022-04-01 03:27:46 root: INFO: instruction count: 39: __C2078etypeDecode.__m2099SKIP_o_struct_of_o_float32END 2022-04-01 03:27:46 root: INFO: instruction count: 129: __C2078etypeDecode.__m2100SKIP_o_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:27:46 root: INFO: instruction count: 129: __C2078etypeDecode.__m2101SKIP_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:27:46 root: INFO: instruction count: 39: __C2078etypeDecode.__m2102SKIP_o_struct_of_o_int32END 2022-04-01 03:27:52 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:53 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:53 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:54 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:54 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:56 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:56 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:56 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:56 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:57 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:57 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:58 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:58 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:58 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:58 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:27:59 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:27:59 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:00 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:00 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:01 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:01 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:02 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:02 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:04 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:04 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:04 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:04 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:05 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.040ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 48: (Coalesce (InsertFields (Let __iruid_4356 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)) (Let __iruid_4357 (GetField alleles_old (Ref __iruid_4356)) (Let __iruid_4358 (GetField locus_old (Ref __iruid_4356)) (InsertFields (Ref __iruid_4356) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos") (mpc (GetField mpc (GetField __uid_46 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)))) (originalAltAlleles (ToArray (StreamMap __iruid_4359 (ToStream False (ApplyIR sliceRight () Array[String] (Ref __iruid_4357) (I32 1))) (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply contig () String (Ref __iruid_4358)) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_4358)))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_4357) (I32 0) (Str " File \"/h..."))) (Str "-")) (Ref __iruid_4359))))) (pos (Apply position () Int32 (GetField locus (Ref __iruid_4356)))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.512ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.102ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.331ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.674ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.098ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.170ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.215ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.145ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.454ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.799ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.113ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.344ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.160ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.091ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.290ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.566ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.091ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.935ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 11.734ms, total 2m48.2s, tagged coverage 94.5 2022-04-01 03:28:05 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 48: (Coalesce (InsertFields (Let __iruid_6329 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)) (Let __iruid_6330 (GetField alleles_old (Ref __iruid_6329)) (Let __iruid_6331 (GetField locus_old (Ref __iruid_6329)) (InsertFields (Ref __iruid_6329) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos") (mpc (GetField mpc (GetField __uid_46 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)))) (originalAltAlleles (ToArray (StreamMap __iruid_6332 (ToStream False (ApplyIR sliceRight () Array[String] (Ref __iruid_6330) (I32 1))) (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply contig () String (Ref __iruid_6331)) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_6331)))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_6330) (I32 0) (Str " File \"/h..."))) (Str "-")) (Ref __iruid_6332))))) (pos (Apply position () Int32 (GetField locus (Ref __iruid_6329)))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 15.669ms, total 2m48.2s, tagged coverage 70.8 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.010ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 15.909ms, total 2m48.2s, tagged coverage 70.0 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.022ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.168ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.065ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.366ms, total 2m48.2s, tagged coverage 69.5 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.010ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 90: (Coalesce (InsertFields (Let __iruid_6329 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)) (Let __iruid_6330 (GetField alleles_old (Ref __iruid_6329)) (Let __iruid_6331 (GetField locus_old (Ref __iruid_6329)) (InsertFields (Ref __iruid_6329) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos") (mpc (GetField mpc (GetField __uid_46 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)))) (originalAltAlleles (ToArray (StreamMap __iruid_6332 (ToStream False (Let __iruid_6342 (Ref __iruid_6330) (Let __iruid_6343 (I32 1) (ToArray (StreamMap __iruid_6344 (StreamRange False (If (ApplyComparisonOp LT (Ref __iruid_6343) (I32 0)) (If (ApplyComparisonOp GT (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_6342)) (Ref __iruid_6343)) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_6342)) (Ref __iruid_6343)) (I32 0)) (Ref __iruid_6343)) (ArrayLen (Ref __iruid_6342)) (I32 1)) (ArrayRef (Ref __iruid_6342) (Ref __iruid_6344) (Str ""))))))) (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply contig () String (Ref __iruid_6331)) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_6331)))) (Str "-")) (Let __iruid_6345 (Ref __iruid_6330) (Let __iruid_6346 (I32 0) (Let __iruid_6347 (Str " File \"/h...") (ArrayRef (Ref __iruid_6345) (If (ApplyComparisonOp LT (Ref __iruid_6346) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_6345)) (Ref __iruid_6346)) (Ref __iruid_6346)) (Ref __iruid_6347)))))) (Str "-")) (Ref __iruid_6332))))) (pos (Apply position () Int32 (GetField locus (Ref __iruid_6329)))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.174ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.197ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.493ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 1.450ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.242ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 3.238ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.604ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.188ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.694ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 1.021ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.186ms, total 2m48.2s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.858ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.158ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.144ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.278ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.939ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.178ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.786ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 16.662ms, total 2m48.3s, tagged coverage 95.0 2022-04-01 03:28:05 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 52: (Coalesce (InsertFields (Let __iruid_6363 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)) (Let __iruid_6364 (GetField alleles_old (Ref __iruid_6363)) (Let __iruid_6365 (GetField locus_old (Ref __iruid_6363)) (InsertFields (Ref __iruid_6363) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos") (mpc (GetField mpc (GetField __uid_46 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)))) (originalAltAlleles (ToArray (StreamMap __iruid_6366 (StreamRange False (I32 1) (ArrayLen (Ref __iruid_6364)) (I32 1)) (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply contig () String (Ref __iruid_6365)) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_6365)))) (Str "-")) (ArrayRef (Ref __iruid_6364) (I32 0) (Str " File \"/h..."))) (Str "-")) (ArrayRef (Ref __iruid_6364) (Ref __iruid_6366) (Str "")))))) (pos (Apply position () Int32 (GetField locus (Ref __iruid_6363)))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 20.633ms, total 2m48.3s, tagged coverage 76.7 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.010ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 20.774ms, total 2m48.3s, tagged coverage 76.3 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.019ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 9.903ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.022ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 10.067ms, total 2m48.3s, tagged coverage 98.8 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.008ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 52: (Coalesce (InsertFields (Let __iruid_6363 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)) (Let __iruid_6364 (GetField alleles_old (Ref __iruid_6363)) (Let __iruid_6365 (GetField locus_old (Ref __iruid_6363)) (InsertFields (Ref __iruid_6363) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos") (mpc (GetField mpc (GetField __uid_46 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)))) (originalAltAlleles (ToArray (StreamMap __iruid_6366 (StreamRange False (I32 1) (ArrayLen (Ref __iruid_6364)) (I32 1)) (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply contig () String (Ref __iruid_6365)) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_6365)))) (Str "-")) (ArrayRef (Ref __iruid_6364) (I32 0) (Str " File \"/h..."))) (Str "-")) (ArrayRef (Ref __iruid_6364) (Ref __iruid_6366) (Str "")))))) (pos (Apply position () Int32 (GetField locus (Ref __iruid_6363)))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.120ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.146ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.301ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.965ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.187ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.779ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.149ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.129ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.263ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 1.435ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.164ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.893ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.159ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.139ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.275ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 1.017ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.188ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.821ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 14.875ms, total 2m48.3s, tagged coverage 95.0 2022-04-01 03:28:05 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 52: (Coalesce (InsertFields (Let __iruid_6375 (SelectFields (locus alleles rsid filters alleles_old locus_old vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)) (Let __iruid_6376 (GetField alleles_old (Ref __iruid_6375)) (Let __iruid_6377 (GetField locus_old (Ref __iruid_6375)) (InsertFields (Ref __iruid_6375) ("locus" "alleles" "rsid" "filters" "alleles_old" "locus_old" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos") (mpc (GetField mpc (GetField __uid_46 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)))) (originalAltAlleles (ToArray (StreamMap __iruid_6378 (StreamRange False (I32 1) (ArrayLen (Ref __iruid_6376)) (I32 1)) (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply contig () String (Ref __iruid_6377)) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_6377)))) (Str "-")) (ArrayRef (Ref __iruid_6376) (I32 0) (Str " File \"/h..."))) (Str "-")) (ArrayRef (Ref __iruid_6376) (Ref __iruid_6378) (Str "")))))) (pos (Apply position () Int32 (GetField locus (Ref __iruid_6375)))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_46:PCStruct{mpc:PCStruct{MPC:PCString}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],alleles_old:Array[String],locus_old:Locus(GRCh38),vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 18.528ms, total 2m48.3s, tagged coverage 76.3 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.011ms, total 2m48.3s 2022-04-01 03:28:05 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 18.667ms, total 2m48.3s, tagged coverage 75.8 2022-04-01 03:28:05 root: INFO: encoder cache hit 2022-04-01 03:28:05 MemoryStore: INFO: Block broadcast_26 stored as values in memory (estimated size 112.0 B, free 5.6 GB) 2022-04-01 03:28:05 MemoryStore: INFO: Block broadcast_26_piece0 stored as bytes in memory (estimated size 114.0 B, free 5.6 GB) 2022-04-01 03:28:05 BlockManagerInfo: INFO: Added broadcast_26_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 114.0 B, free: 5.6 GB) 2022-04-01 03:28:05 SparkContext: INFO: Created broadcast 26 from broadcast at SparkBackend.scala:233 2022-04-01 03:28:05 root: INFO: instruction count: 6: __C2103Compiled. 2022-04-01 03:28:05 root: INFO: instruction count: 438: __C2103Compiled.apply 2022-04-01 03:28:05 root: INFO: instruction count: 11: __C2103Compiled.__m2109addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 8: __C2103Compiled.__m2110addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 8: __C2103Compiled.__m2111addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 8: __C2103Compiled.__m2112addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 11: __C2103Compiled.__m2113addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 8: __C2103Compiled.__m2114addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 11: __C2103Compiled.__m2115addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 11: __C2103Compiled.__m2116addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 8: __C2103Compiled.__m2117addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 8: __C2103Compiled.__m2118addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 11: __C2103Compiled.__m2119addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 11: __C2103Compiled.__m2120addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 11: __C2103Compiled.__m2121addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 11: __C2103Compiled.__m2122addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 11: __C2103Compiled.__m2123addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 8: __C2103Compiled.__m2124addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 11: __C2103Compiled.__m2125addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 11: __C2103Compiled.__m2126addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 11: __C2103Compiled.__m2138addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 83: __C2103Compiled.__m2153concat 2022-04-01 03:28:05 root: INFO: instruction count: 11: __C2103Compiled.__m2156contig 2022-04-01 03:28:05 root: INFO: instruction count: 61: __C2103Compiled.__m2158str 2022-04-01 03:28:05 root: INFO: instruction count: 15: __C2103Compiled.__m2161setup_null 2022-04-01 03:28:05 root: INFO: instruction count: 11: __C2103Compiled.__m2164position 2022-04-01 03:28:05 root: INFO: instruction count: 8: __C2103Compiled.__m2168addIRIntermediate 2022-04-01 03:28:05 root: INFO: instruction count: 14: __C2103Compiled.setPartitionIndex 2022-04-01 03:28:05 root: INFO: instruction count: 7: __C2103Compiled.addPartitionRegion 2022-04-01 03:28:05 root: INFO: instruction count: 25: __C2103Compiled.__m2172DECODE_r_struct_of_r_binaryANDr_binaryEND_TO_r_tuple_of_r_stringANDr_stringEND 2022-04-01 03:28:05 root: INFO: instruction count: 18: __C2103Compiled.__m2173read_fields_group_0 2022-04-01 03:28:05 root: INFO: instruction count: 34: __C2103Compiled.__m2174INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:28:05 root: INFO: instruction count: 50: __C2103Compiled.addLiterals 2022-04-01 03:28:05 root: INFO: instruction count: 197: __C2103Compiled.applyregion188_195 2022-04-01 03:28:05 root: INFO: instruction count: 129: __C2103Compiled.applyregion268_275 2022-04-01 03:28:05 root: INFO: instruction count: 122: __C2103Compiled.applyregion220_227 2022-04-01 03:28:05 root: INFO: instruction count: 102: __C2103Compiled.applyregion204_211 2022-04-01 03:28:05 root: INFO: instruction count: 102: __C2103Compiled.applyregion244_251 2022-04-01 03:28:05 root: INFO: instruction count: 100: __C2103Compiled.applyregion228_235 2022-04-01 03:28:05 root: INFO: instruction count: 747: __C2103Compiled.applyregion187_285 2022-04-01 03:28:05 root: INFO: instruction count: 253: __C2103Compiled.applyregion168_286 2022-04-01 03:28:05 root: INFO: instruction count: 219: __C2103Compiled.applyregion80_87 2022-04-01 03:28:05 root: INFO: instruction count: 188: __C2103Compiled.applyregion0_7 2022-04-01 03:28:05 root: INFO: instruction count: 136: __C2103Compiled.applyregion88_95 2022-04-01 03:28:05 root: INFO: instruction count: 122: __C2103Compiled.applyregion32_39 2022-04-01 03:28:05 root: INFO: instruction count: 106: __C2103Compiled.applyregion112_119 2022-04-01 03:28:05 root: INFO: instruction count: 102: __C2103Compiled.applyregion96_103 2022-04-01 03:28:05 root: INFO: instruction count: 102: __C2103Compiled.applyregion16_23 2022-04-01 03:28:05 root: INFO: instruction count: 102: __C2103Compiled.applyregion120_127 2022-04-01 03:28:05 root: INFO: instruction count: 102: __C2103Compiled.applyregion56_63 2022-04-01 03:28:05 root: INFO: instruction count: 100: __C2103Compiled.applyregion144_151 2022-04-01 03:28:05 root: INFO: instruction count: 100: __C2103Compiled.applyregion40_47 2022-04-01 03:28:05 root: INFO: instruction count: 98: __C2103Compiled.applyregion8_15 2022-04-01 03:28:05 root: INFO: instruction count: 98: __C2103Compiled.applyregion24_31 2022-04-01 03:28:05 root: INFO: instruction count: 96: __C2103Compiled.applyregion128_135 2022-04-01 03:28:05 root: INFO: instruction count: 96: __C2103Compiled.applyregion104_111 2022-04-01 03:28:05 root: INFO: instruction count: 82: __C2103Compiled.applyregion136_143 2022-04-01 03:28:05 root: INFO: instruction count: 6: __C2176applySpills. 2022-04-01 03:28:06 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:06 root: INFO: decoder cache hit 2022-04-01 03:28:06 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/parts/part-0' for reading 2022-04-01 03:28:06 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:07 root: INFO: decoder cache miss (13 hits, 22 misses, 0.371 2022-04-01 03:28:07 root: INFO: instruction count: 6: __C2213etypeDecode. 2022-04-01 03:28:07 root: INFO: instruction count: 8: __C2213etypeDecode.apply 2022-04-01 03:28:07 root: INFO: instruction count: 47: __C2213etypeDecode.__m2214DECODE_r_struct_of_o_struct_of_r_binaryANDr_int32ENDANDo_array_of_o_binaryANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_struct_of_o_binaryENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryENDANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_int32ENDANDo_float32ANDo_float64END_TO_r_tuple_of_o_locusANDo_array_of_o_stringANDo_tuple_of_o_float64ENDEND 2022-04-01 03:28:07 root: INFO: instruction count: 283: __C2213etypeDecode.__m2215read_fields_group_0 2022-04-01 03:28:07 root: INFO: instruction count: 17: __C2213etypeDecode.__m2216INPLACE_DECODE_o_struct_of_r_binaryANDr_int32END_TO_o_tuple_of_r_binaryANDr_int32END 2022-04-01 03:28:07 root: INFO: instruction count: 18: __C2213etypeDecode.__m2217read_fields_group_0 2022-04-01 03:28:07 root: INFO: instruction count: 34: __C2213etypeDecode.__m2218INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:28:07 root: INFO: instruction count: 11: __C2213etypeDecode.__m2219INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:28:07 root: INFO: instruction count: 105: __C2213etypeDecode.__m2220INPLACE_DECODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:28:07 root: INFO: instruction count: 34: __C2213etypeDecode.__m2221INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:28:07 root: INFO: instruction count: 84: __C2213etypeDecode.__m2222SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64END 2022-04-01 03:28:07 root: INFO: instruction count: 6: __C2213etypeDecode.__m2223SKIP_o_int32 2022-04-01 03:28:07 root: INFO: instruction count: 6: __C2213etypeDecode.__m2224SKIP_o_float64 2022-04-01 03:28:07 root: INFO: instruction count: 39: __C2213etypeDecode.__m2225SKIP_o_struct_of_o_binaryEND 2022-04-01 03:28:07 root: INFO: instruction count: 10: __C2213etypeDecode.__m2226SKIP_o_binary 2022-04-01 03:28:07 root: INFO: instruction count: 39: __C2213etypeDecode.__m2227SKIP_o_struct_of_o_float32END 2022-04-01 03:28:07 root: INFO: instruction count: 6: __C2213etypeDecode.__m2228SKIP_o_float32 2022-04-01 03:28:07 root: INFO: instruction count: 39: __C2213etypeDecode.__m2229SKIP_o_struct_of_o_float64END 2022-04-01 03:28:07 root: INFO: instruction count: 144: __C2213etypeDecode.__m2230SKIP_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:28:07 root: INFO: instruction count: 99: __C2213etypeDecode.__m2231SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:28:07 root: INFO: instruction count: 30: __C2213etypeDecode.__m2232INPLACE_DECODE_o_struct_of_o_float64END_TO_o_tuple_of_o_float64END 2022-04-01 03:28:07 root: INFO: instruction count: 32: __C2213etypeDecode.__m2233read_fields_group_0 2022-04-01 03:28:07 root: INFO: instruction count: 11: __C2213etypeDecode.__m2234INPLACE_DECODE_o_float64_TO_o_float64 2022-04-01 03:28:07 root: INFO: instruction count: 39: __C2213etypeDecode.__m2235SKIP_o_struct_of_o_float32END 2022-04-01 03:28:07 root: INFO: instruction count: 129: __C2213etypeDecode.__m2236SKIP_o_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:28:07 root: INFO: instruction count: 129: __C2213etypeDecode.__m2237SKIP_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:28:07 root: INFO: instruction count: 39: __C2213etypeDecode.__m2238SKIP_o_struct_of_o_int32END 2022-04-01 03:28:15 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:16 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:16 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:17 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:17 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:18 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:18 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:19 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:19 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:19 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:19 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:20 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:20 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:21 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:21 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:22 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:22 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:23 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:23 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:24 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:24 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:24 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:24 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:25 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:25 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:26 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:26 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:27 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:28 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:28 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.128ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 624: (Coalesce (InsertFields (Let __iruid_4363 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)) (Let __iruid_4364 (GetField genotypes (Ref __iruid_4363)) (Let __iruid_4365 (GetField genotypes (Ref __iruid_4363)) (Let __iruid_4366 (GetField genotypes (Ref __iruid_4363)) (InsertFields (Ref __iruid_4363) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt") (primate_ai (GetField primate_ai (GetField __uid_48 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)))) (ref (ApplyIR indexArray () String (GetField alleles (Ref __iruid_4363)) (I32 0) (Str " File \"/h..."))) (rsid (GetField rsid (Ref __iruid_4363))) (samples_ab (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_4367 (StreamFilter __iruid_4368 (ToStream False (Ref __iruid_4364)) (Let __iruid_4369 (GetField ab (Ref __iruid_4368)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4368)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4369) (F64 100.0)) (F64 0.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4369) (F64 100.0)) (F64 5.0))))) (GetField sample_id (Ref __iruid_4367))))) (5_to_10 (ToSet (StreamMap __iruid_4370 (StreamFilter __iruid_4371 (ToStream False (Ref __iruid_4364)) (Let __iruid_4372 (GetField ab (Ref __iruid_4371)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4371)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4372) (F64 100.0)) (F64 5.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4372) (F64 100.0)) (F64 10.0))))) (GetField sample_id (Ref __iruid_4370))))) (10_to_15 (ToSet (StreamMap __iruid_4373 (StreamFilter __iruid_4374 (ToStream False (Ref __iruid_4364)) (Let __iruid_4375 (GetField ab (Ref __iruid_4374)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4374)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4375) (F64 100.0)) (F64 10.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4375) (F64 100.0)) (F64 15.0))))) (GetField sample_id (Ref __iruid_4373))))) (15_to_20 (ToSet (StreamMap __iruid_4376 (StreamFilter __iruid_4377 (ToStream False (Ref __iruid_4364)) (Let __iruid_4378 (GetField ab (Ref __iruid_4377)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4377)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4378) (F64 100.0)) (F64 15.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4378) (F64 100.0)) (F64 20.0))))) (GetField sample_id (Ref __iruid_4376))))) (20_to_25 (ToSet (StreamMap __iruid_4379 (StreamFilter __iruid_4380 (ToStream False (Ref __iruid_4364)) (Let __iruid_4381 (GetField ab (Ref __iruid_4380)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4380)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4381) (F64 100.0)) (F64 20.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4381) (F64 100.0)) (F64 25.0))))) (GetField sample_id (Ref __iruid_4379))))) (25_to_30 (ToSet (StreamMap __iruid_4382 (StreamFilter __iruid_4383 (ToStream False (Ref __iruid_4364)) (Let __iruid_4384 (GetField ab (Ref __iruid_4383)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4383)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4384) (F64 100.0)) (F64 25.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4384) (F64 100.0)) (F64 30.0))))) (GetField sample_id (Ref __iruid_4382))))) (30_to_35 (ToSet (StreamMap __iruid_4385 (StreamFilter __iruid_4386 (ToStream False (Ref __iruid_4364)) (Let __iruid_4387 (GetField ab (Ref __iruid_4386)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4386)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4387) (F64 100.0)) (F64 30.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4387) (F64 100.0)) (F64 35.0))))) (GetField sample_id (Ref __iruid_4385))))) (35_to_40 (ToSet (StreamMap __iruid_4388 (StreamFilter __iruid_4389 (ToStream False (Ref __iruid_4364)) (Let __iruid_4390 (GetField ab (Ref __iruid_4389)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4389)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4390) (F64 100.0)) (F64 35.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4390) (F64 100.0)) (F64 40.0))))) (GetField sample_id (Ref __iruid_4388))))) (40_to_45 (ToSet (StreamMap __iruid_4391 (StreamFilter __iruid_4392 (ToStream False (Ref __iruid_4364)) (Let __iruid_4393 (GetField ab (Ref __iruid_4392)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4392)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_4393) (F64 100.0)) (F64 40.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_4393) (F64 100.0)) (F64 45.0))))) (GetField sample_id (Ref __iruid_4391))))))) (samples_gq (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_4394 (StreamFilter __iruid_4395 (ToStream False (Ref __iruid_4365)) (Let __iruid_4396 (GetField gq (Ref __iruid_4395)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4396) (I32 0)) (ApplyComparisonOp LT (Ref __iruid_4396) (I32 5))))) (GetField sample_id (Ref __iruid_4394))))) (5_to_10 (ToSet (StreamMap __iruid_4397 (StreamFilter __iruid_4398 (ToStream False (Ref __iruid_4365)) (Let __iruid_4399 (GetField gq (Ref __iruid_4398)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4399) (I32 5)) (ApplyComparisonOp LT (Ref __iruid_4399) (I32 10))))) (GetField sample_id (Ref __iruid_4397))))) (10_to_15 (ToSet (StreamMap __iruid_4400 (StreamFilter __iruid_4401 (ToStream False (Ref __iruid_4365)) (Let __iruid_4402 (GetField gq (Ref __iruid_4401)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4402) (I32 10)) (ApplyComparisonOp LT (Ref __iruid_4402) (I32 15))))) (GetField sample_id (Ref __iruid_4400))))) (15_to_20 (ToSet (StreamMap __iruid_4403 (StreamFilter __iruid_4404 (ToStream False (Ref __iruid_4365)) (Let __iruid_4405 (GetField gq (Ref __iruid_4404)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4405) (I32 15)) (ApplyComparisonOp LT (Ref __iruid_4405) (I32 20))))) (GetField sample_id (Ref __iruid_4403))))) (20_to_25 (ToSet (StreamMap __iruid_4406 (StreamFilter __iruid_4407 (ToStream False (Ref __iruid_4365)) (Let __iruid_4408 (GetField gq (Ref __iruid_4407)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4408) (I32 20)) (ApplyComparisonOp LT (Ref __iruid_4408) (I32 25))))) (GetField sample_id (Ref __iruid_4406))))) (25_to_30 (ToSet (StreamMap __iruid_4409 (StreamFilter __iruid_4410 (ToStream False (Ref __iruid_4365)) (Let __iruid_4411 (GetField gq (Ref __iruid_4410)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4411) (I32 25)) (ApplyComparisonOp LT (Ref __iruid_4411) (I32 30))))) (GetField sample_id (Ref __iruid_4409))))) (30_to_35 (ToSet (StreamMap __iruid_4412 (StreamFilter __iruid_4413 (ToStream False (Ref __iruid_4365)) (Let __iruid_4414 (GetField gq (Ref __iruid_4413)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4414) (I32 30)) (ApplyComparisonOp LT (Ref __iruid_4414) (I32 35))))) (GetField sample_id (Ref __iruid_4412))))) (35_to_40 (ToSet (StreamMap __iruid_4415 (StreamFilter __iruid_4416 (ToStream False (Ref __iruid_4365)) (Let __iruid_4417 (GetField gq (Ref __iruid_4416)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4417) (I32 35)) (ApplyComparisonOp LT (Ref __iruid_4417) (I32 40))))) (GetField sample_id (Ref __iruid_4415))))) (40_to_45 (ToSet (StreamMap __iruid_4418 (StreamFilter __iruid_4419 (ToStream False (Ref __iruid_4365)) (Let __iruid_4420 (GetField gq (Ref __iruid_4419)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4420) (I32 40)) (ApplyComparisonOp LT (Ref __iruid_4420) (I32 45))))) (GetField sample_id (Ref __iruid_4418))))) (45_to_50 (ToSet (StreamMap __iruid_4421 (StreamFilter __iruid_4422 (ToStream False (Ref __iruid_4365)) (Let __iruid_4423 (GetField gq (Ref __iruid_4422)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4423) (I32 45)) (ApplyComparisonOp LT (Ref __iruid_4423) (I32 50))))) (GetField sample_id (Ref __iruid_4421))))) (50_to_55 (ToSet (StreamMap __iruid_4424 (StreamFilter __iruid_4425 (ToStream False (Ref __iruid_4365)) (Let __iruid_4426 (GetField gq (Ref __iruid_4425)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4426) (I32 50)) (ApplyComparisonOp LT (Ref __iruid_4426) (I32 55))))) (GetField sample_id (Ref __iruid_4424))))) (55_to_60 (ToSet (StreamMap __iruid_4427 (StreamFilter __iruid_4428 (ToStream False (Ref __iruid_4365)) (Let __iruid_4429 (GetField gq (Ref __iruid_4428)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4429) (I32 55)) (ApplyComparisonOp LT (Ref __iruid_4429) (I32 60))))) (GetField sample_id (Ref __iruid_4427))))) (60_to_65 (ToSet (StreamMap __iruid_4430 (StreamFilter __iruid_4431 (ToStream False (Ref __iruid_4365)) (Let __iruid_4432 (GetField gq (Ref __iruid_4431)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4432) (I32 60)) (ApplyComparisonOp LT (Ref __iruid_4432) (I32 65))))) (GetField sample_id (Ref __iruid_4430))))) (65_to_70 (ToSet (StreamMap __iruid_4433 (StreamFilter __iruid_4434 (ToStream False (Ref __iruid_4365)) (Let __iruid_4435 (GetField gq (Ref __iruid_4434)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4435) (I32 65)) (ApplyComparisonOp LT (Ref __iruid_4435) (I32 70))))) (GetField sample_id (Ref __iruid_4433))))) (70_to_75 (ToSet (StreamMap __iruid_4436 (StreamFilter __iruid_4437 (ToStream False (Ref __iruid_4365)) (Let __iruid_4438 (GetField gq (Ref __iruid_4437)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4438) (I32 70)) (ApplyComparisonOp LT (Ref __iruid_4438) (I32 75))))) (GetField sample_id (Ref __iruid_4436))))) (75_to_80 (ToSet (StreamMap __iruid_4439 (StreamFilter __iruid_4440 (ToStream False (Ref __iruid_4365)) (Let __iruid_4441 (GetField gq (Ref __iruid_4440)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4441) (I32 75)) (ApplyComparisonOp LT (Ref __iruid_4441) (I32 80))))) (GetField sample_id (Ref __iruid_4439))))) (80_to_85 (ToSet (StreamMap __iruid_4442 (StreamFilter __iruid_4443 (ToStream False (Ref __iruid_4365)) (Let __iruid_4444 (GetField gq (Ref __iruid_4443)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4444) (I32 80)) (ApplyComparisonOp LT (Ref __iruid_4444) (I32 85))))) (GetField sample_id (Ref __iruid_4442))))) (85_to_90 (ToSet (StreamMap __iruid_4445 (StreamFilter __iruid_4446 (ToStream False (Ref __iruid_4365)) (Let __iruid_4447 (GetField gq (Ref __iruid_4446)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4447) (I32 85)) (ApplyComparisonOp LT (Ref __iruid_4447) (I32 90))))) (GetField sample_id (Ref __iruid_4445))))) (90_to_95 (ToSet (StreamMap __iruid_4448 (StreamFilter __iruid_4449 (ToStream False (Ref __iruid_4365)) (Let __iruid_4450 (GetField gq (Ref __iruid_4449)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_4450) (I32 90)) (ApplyComparisonOp LT (Ref __iruid_4450) (I32 95))))) (GetField sample_id (Ref __iruid_4448))))))) (samples_no_call (ToSet (StreamMap __iruid_4451 (StreamFilter __iruid_4452 (ToStream False (GetField genotypes (Ref __iruid_4363))) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4452)) (I32 -1))) (GetField sample_id (Ref __iruid_4451))))) (samples_num_alt (MakeStruct (1 (ToSet (StreamMap __iruid_4453 (StreamFilter __iruid_4454 (ToStream False (Ref __iruid_4366)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4454)) (I32 1))) (GetField sample_id (Ref __iruid_4453))))) (2 (ToSet (StreamMap __iruid_4455 (StreamFilter __iruid_4456 (ToStream False (Ref __iruid_4366)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_4456)) (I32 2))) (GetField sample_id (Ref __iruid_4455)))))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 1.349ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.789ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 2.629ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 6.774ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.898ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 12.475ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 1.617ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 1.213ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 2.558ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 7.814ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 1.189ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 9.829ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 1.619ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.921ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 1.771ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 5.827ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 1.439ms, total 3m10.9s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 12.378ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 74.111ms, total 3m11.0s, tagged coverage 98.6 2022-04-01 03:28:28 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 624: (Coalesce (InsertFields (Let __iruid_6595 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)) (Let __iruid_6596 (GetField genotypes (Ref __iruid_6595)) (Let __iruid_6597 (GetField genotypes (Ref __iruid_6595)) (Let __iruid_6598 (GetField genotypes (Ref __iruid_6595)) (InsertFields (Ref __iruid_6595) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt") (primate_ai (GetField primate_ai (GetField __uid_48 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)))) (ref (ApplyIR indexArray () String (GetField alleles (Ref __iruid_6595)) (I32 0) (Str " File \"/h..."))) (rsid (GetField rsid (Ref __iruid_6595))) (samples_ab (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_6599 (StreamFilter __iruid_6600 (ToStream False (Ref __iruid_6596)) (Let __iruid_6601 (GetField ab (Ref __iruid_6600)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6600)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6601) (F64 100.0)) (F64 0.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6601) (F64 100.0)) (F64 5.0))))) (GetField sample_id (Ref __iruid_6599))))) (5_to_10 (ToSet (StreamMap __iruid_6602 (StreamFilter __iruid_6603 (ToStream False (Ref __iruid_6596)) (Let __iruid_6604 (GetField ab (Ref __iruid_6603)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6603)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6604) (F64 100.0)) (F64 5.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6604) (F64 100.0)) (F64 10.0))))) (GetField sample_id (Ref __iruid_6602))))) (10_to_15 (ToSet (StreamMap __iruid_6605 (StreamFilter __iruid_6606 (ToStream False (Ref __iruid_6596)) (Let __iruid_6607 (GetField ab (Ref __iruid_6606)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6606)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6607) (F64 100.0)) (F64 10.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6607) (F64 100.0)) (F64 15.0))))) (GetField sample_id (Ref __iruid_6605))))) (15_to_20 (ToSet (StreamMap __iruid_6608 (StreamFilter __iruid_6609 (ToStream False (Ref __iruid_6596)) (Let __iruid_6610 (GetField ab (Ref __iruid_6609)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6609)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6610) (F64 100.0)) (F64 15.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6610) (F64 100.0)) (F64 20.0))))) (GetField sample_id (Ref __iruid_6608))))) (20_to_25 (ToSet (StreamMap __iruid_6611 (StreamFilter __iruid_6612 (ToStream False (Ref __iruid_6596)) (Let __iruid_6613 (GetField ab (Ref __iruid_6612)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6612)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6613) (F64 100.0)) (F64 20.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6613) (F64 100.0)) (F64 25.0))))) (GetField sample_id (Ref __iruid_6611))))) (25_to_30 (ToSet (StreamMap __iruid_6614 (StreamFilter __iruid_6615 (ToStream False (Ref __iruid_6596)) (Let __iruid_6616 (GetField ab (Ref __iruid_6615)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6615)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6616) (F64 100.0)) (F64 25.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6616) (F64 100.0)) (F64 30.0))))) (GetField sample_id (Ref __iruid_6614))))) (30_to_35 (ToSet (StreamMap __iruid_6617 (StreamFilter __iruid_6618 (ToStream False (Ref __iruid_6596)) (Let __iruid_6619 (GetField ab (Ref __iruid_6618)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6618)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6619) (F64 100.0)) (F64 30.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6619) (F64 100.0)) (F64 35.0))))) (GetField sample_id (Ref __iruid_6617))))) (35_to_40 (ToSet (StreamMap __iruid_6620 (StreamFilter __iruid_6621 (ToStream False (Ref __iruid_6596)) (Let __iruid_6622 (GetField ab (Ref __iruid_6621)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6621)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6622) (F64 100.0)) (F64 35.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6622) (F64 100.0)) (F64 40.0))))) (GetField sample_id (Ref __iruid_6620))))) (40_to_45 (ToSet (StreamMap __iruid_6623 (StreamFilter __iruid_6624 (ToStream False (Ref __iruid_6596)) (Let __iruid_6625 (GetField ab (Ref __iruid_6624)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6624)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6625) (F64 100.0)) (F64 40.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6625) (F64 100.0)) (F64 45.0))))) (GetField sample_id (Ref __iruid_6623))))))) (samples_gq (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_6626 (StreamFilter __iruid_6627 (ToStream False (Ref __iruid_6597)) (Let __iruid_6628 (GetField gq (Ref __iruid_6627)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6628) (I32 0)) (ApplyComparisonOp LT (Ref __iruid_6628) (I32 5))))) (GetField sample_id (Ref __iruid_6626))))) (5_to_10 (ToSet (StreamMap __iruid_6629 (StreamFilter __iruid_6630 (ToStream False (Ref __iruid_6597)) (Let __iruid_6631 (GetField gq (Ref __iruid_6630)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6631) (I32 5)) (ApplyComparisonOp LT (Ref __iruid_6631) (I32 10))))) (GetField sample_id (Ref __iruid_6629))))) (10_to_15 (ToSet (StreamMap __iruid_6632 (StreamFilter __iruid_6633 (ToStream False (Ref __iruid_6597)) (Let __iruid_6634 (GetField gq (Ref __iruid_6633)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6634) (I32 10)) (ApplyComparisonOp LT (Ref __iruid_6634) (I32 15))))) (GetField sample_id (Ref __iruid_6632))))) (15_to_20 (ToSet (StreamMap __iruid_6635 (StreamFilter __iruid_6636 (ToStream False (Ref __iruid_6597)) (Let __iruid_6637 (GetField gq (Ref __iruid_6636)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6637) (I32 15)) (ApplyComparisonOp LT (Ref __iruid_6637) (I32 20))))) (GetField sample_id (Ref __iruid_6635))))) (20_to_25 (ToSet (StreamMap __iruid_6638 (StreamFilter __iruid_6639 (ToStream False (Ref __iruid_6597)) (Let __iruid_6640 (GetField gq (Ref __iruid_6639)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6640) (I32 20)) (ApplyComparisonOp LT (Ref __iruid_6640) (I32 25))))) (GetField sample_id (Ref __iruid_6638))))) (25_to_30 (ToSet (StreamMap __iruid_6641 (StreamFilter __iruid_6642 (ToStream False (Ref __iruid_6597)) (Let __iruid_6643 (GetField gq (Ref __iruid_6642)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6643) (I32 25)) (ApplyComparisonOp LT (Ref __iruid_6643) (I32 30))))) (GetField sample_id (Ref __iruid_6641))))) (30_to_35 (ToSet (StreamMap __iruid_6644 (StreamFilter __iruid_6645 (ToStream False (Ref __iruid_6597)) (Let __iruid_6646 (GetField gq (Ref __iruid_6645)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6646) (I32 30)) (ApplyComparisonOp LT (Ref __iruid_6646) (I32 35))))) (GetField sample_id (Ref __iruid_6644))))) (35_to_40 (ToSet (StreamMap __iruid_6647 (StreamFilter __iruid_6648 (ToStream False (Ref __iruid_6597)) (Let __iruid_6649 (GetField gq (Ref __iruid_6648)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6649) (I32 35)) (ApplyComparisonOp LT (Ref __iruid_6649) (I32 40))))) (GetField sample_id (Ref __iruid_6647))))) (40_to_45 (ToSet (StreamMap __iruid_6650 (StreamFilter __iruid_6651 (ToStream False (Ref __iruid_6597)) (Let __iruid_6652 (GetField gq (Ref __iruid_6651)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6652) (I32 40)) (ApplyComparisonOp LT (Ref __iruid_6652) (I32 45))))) (GetField sample_id (Ref __iruid_6650))))) (45_to_50 (ToSet (StreamMap __iruid_6653 (StreamFilter __iruid_6654 (ToStream False (Ref __iruid_6597)) (Let __iruid_6655 (GetField gq (Ref __iruid_6654)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6655) (I32 45)) (ApplyComparisonOp LT (Ref __iruid_6655) (I32 50))))) (GetField sample_id (Ref __iruid_6653))))) (50_to_55 (ToSet (StreamMap __iruid_6656 (StreamFilter __iruid_6657 (ToStream False (Ref __iruid_6597)) (Let __iruid_6658 (GetField gq (Ref __iruid_6657)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6658) (I32 50)) (ApplyComparisonOp LT (Ref __iruid_6658) (I32 55))))) (GetField sample_id (Ref __iruid_6656))))) (55_to_60 (ToSet (StreamMap __iruid_6659 (StreamFilter __iruid_6660 (ToStream False (Ref __iruid_6597)) (Let __iruid_6661 (GetField gq (Ref __iruid_6660)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6661) (I32 55)) (ApplyComparisonOp LT (Ref __iruid_6661) (I32 60))))) (GetField sample_id (Ref __iruid_6659))))) (60_to_65 (ToSet (StreamMap __iruid_6662 (StreamFilter __iruid_6663 (ToStream False (Ref __iruid_6597)) (Let __iruid_6664 (GetField gq (Ref __iruid_6663)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6664) (I32 60)) (ApplyComparisonOp LT (Ref __iruid_6664) (I32 65))))) (GetField sample_id (Ref __iruid_6662))))) (65_to_70 (ToSet (StreamMap __iruid_6665 (StreamFilter __iruid_6666 (ToStream False (Ref __iruid_6597)) (Let __iruid_6667 (GetField gq (Ref __iruid_6666)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6667) (I32 65)) (ApplyComparisonOp LT (Ref __iruid_6667) (I32 70))))) (GetField sample_id (Ref __iruid_6665))))) (70_to_75 (ToSet (StreamMap __iruid_6668 (StreamFilter __iruid_6669 (ToStream False (Ref __iruid_6597)) (Let __iruid_6670 (GetField gq (Ref __iruid_6669)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6670) (I32 70)) (ApplyComparisonOp LT (Ref __iruid_6670) (I32 75))))) (GetField sample_id (Ref __iruid_6668))))) (75_to_80 (ToSet (StreamMap __iruid_6671 (StreamFilter __iruid_6672 (ToStream False (Ref __iruid_6597)) (Let __iruid_6673 (GetField gq (Ref __iruid_6672)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6673) (I32 75)) (ApplyComparisonOp LT (Ref __iruid_6673) (I32 80))))) (GetField sample_id (Ref __iruid_6671))))) (80_to_85 (ToSet (StreamMap __iruid_6674 (StreamFilter __iruid_6675 (ToStream False (Ref __iruid_6597)) (Let __iruid_6676 (GetField gq (Ref __iruid_6675)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6676) (I32 80)) (ApplyComparisonOp LT (Ref __iruid_6676) (I32 85))))) (GetField sample_id (Ref __iruid_6674))))) (85_to_90 (ToSet (StreamMap __iruid_6677 (StreamFilter __iruid_6678 (ToStream False (Ref __iruid_6597)) (Let __iruid_6679 (GetField gq (Ref __iruid_6678)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6679) (I32 85)) (ApplyComparisonOp LT (Ref __iruid_6679) (I32 90))))) (GetField sample_id (Ref __iruid_6677))))) (90_to_95 (ToSet (StreamMap __iruid_6680 (StreamFilter __iruid_6681 (ToStream False (Ref __iruid_6597)) (Let __iruid_6682 (GetField gq (Ref __iruid_6681)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6682) (I32 90)) (ApplyComparisonOp LT (Ref __iruid_6682) (I32 95))))) (GetField sample_id (Ref __iruid_6680))))))) (samples_no_call (ToSet (StreamMap __iruid_6683 (StreamFilter __iruid_6684 (ToStream False (GetField genotypes (Ref __iruid_6595))) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6684)) (I32 -1))) (GetField sample_id (Ref __iruid_6683))))) (samples_num_alt (MakeStruct (1 (ToSet (StreamMap __iruid_6685 (StreamFilter __iruid_6686 (ToStream False (Ref __iruid_6598)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6686)) (I32 1))) (GetField sample_id (Ref __iruid_6685))))) (2 (ToSet (StreamMap __iruid_6687 (StreamFilter __iruid_6688 (ToStream False (Ref __iruid_6598)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6688)) (I32 2))) (GetField sample_id (Ref __iruid_6687)))))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 82.464ms, total 3m11.0s, tagged coverage 88.6 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.031ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 82.821ms, total 3m11.0s, tagged coverage 88.4 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.178ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.631ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.199ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 1.136ms, total 3m11.0s, tagged coverage 88.7 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.025ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 638: (Coalesce (InsertFields (Let __iruid_6595 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)) (Let __iruid_6596 (GetField genotypes (Ref __iruid_6595)) (Let __iruid_6597 (GetField genotypes (Ref __iruid_6595)) (Let __iruid_6598 (GetField genotypes (Ref __iruid_6595)) (InsertFields (Ref __iruid_6595) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt") (primate_ai (GetField primate_ai (GetField __uid_48 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)))) (ref (Let __iruid_6692 (GetField alleles (Ref __iruid_6595)) (Let __iruid_6693 (I32 0) (Let __iruid_6694 (Str " File \"/h...") (ArrayRef (Ref __iruid_6692) (If (ApplyComparisonOp LT (Ref __iruid_6693) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_6692)) (Ref __iruid_6693)) (Ref __iruid_6693)) (Ref __iruid_6694)))))) (rsid (GetField rsid (Ref __iruid_6595))) (samples_ab (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_6599 (StreamFilter __iruid_6600 (ToStream False (Ref __iruid_6596)) (Let __iruid_6601 (GetField ab (Ref __iruid_6600)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6600)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6601) (F64 100.0)) (F64 0.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6601) (F64 100.0)) (F64 5.0))))) (GetField sample_id (Ref __iruid_6599))))) (5_to_10 (ToSet (StreamMap __iruid_6602 (StreamFilter __iruid_6603 (ToStream False (Ref __iruid_6596)) (Let __iruid_6604 (GetField ab (Ref __iruid_6603)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6603)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6604) (F64 100.0)) (F64 5.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6604) (F64 100.0)) (F64 10.0))))) (GetField sample_id (Ref __iruid_6602))))) (10_to_15 (ToSet (StreamMap __iruid_6605 (StreamFilter __iruid_6606 (ToStream False (Ref __iruid_6596)) (Let __iruid_6607 (GetField ab (Ref __iruid_6606)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6606)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6607) (F64 100.0)) (F64 10.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6607) (F64 100.0)) (F64 15.0))))) (GetField sample_id (Ref __iruid_6605))))) (15_to_20 (ToSet (StreamMap __iruid_6608 (StreamFilter __iruid_6609 (ToStream False (Ref __iruid_6596)) (Let __iruid_6610 (GetField ab (Ref __iruid_6609)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6609)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6610) (F64 100.0)) (F64 15.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6610) (F64 100.0)) (F64 20.0))))) (GetField sample_id (Ref __iruid_6608))))) (20_to_25 (ToSet (StreamMap __iruid_6611 (StreamFilter __iruid_6612 (ToStream False (Ref __iruid_6596)) (Let __iruid_6613 (GetField ab (Ref __iruid_6612)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6612)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6613) (F64 100.0)) (F64 20.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6613) (F64 100.0)) (F64 25.0))))) (GetField sample_id (Ref __iruid_6611))))) (25_to_30 (ToSet (StreamMap __iruid_6614 (StreamFilter __iruid_6615 (ToStream False (Ref __iruid_6596)) (Let __iruid_6616 (GetField ab (Ref __iruid_6615)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6615)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6616) (F64 100.0)) (F64 25.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6616) (F64 100.0)) (F64 30.0))))) (GetField sample_id (Ref __iruid_6614))))) (30_to_35 (ToSet (StreamMap __iruid_6617 (StreamFilter __iruid_6618 (ToStream False (Ref __iruid_6596)) (Let __iruid_6619 (GetField ab (Ref __iruid_6618)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6618)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6619) (F64 100.0)) (F64 30.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6619) (F64 100.0)) (F64 35.0))))) (GetField sample_id (Ref __iruid_6617))))) (35_to_40 (ToSet (StreamMap __iruid_6620 (StreamFilter __iruid_6621 (ToStream False (Ref __iruid_6596)) (Let __iruid_6622 (GetField ab (Ref __iruid_6621)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6621)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6622) (F64 100.0)) (F64 35.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6622) (F64 100.0)) (F64 40.0))))) (GetField sample_id (Ref __iruid_6620))))) (40_to_45 (ToSet (StreamMap __iruid_6623 (StreamFilter __iruid_6624 (ToStream False (Ref __iruid_6596)) (Let __iruid_6625 (GetField ab (Ref __iruid_6624)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6624)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6625) (F64 100.0)) (F64 40.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6625) (F64 100.0)) (F64 45.0))))) (GetField sample_id (Ref __iruid_6623))))))) (samples_gq (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_6626 (StreamFilter __iruid_6627 (ToStream False (Ref __iruid_6597)) (Let __iruid_6628 (GetField gq (Ref __iruid_6627)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6628) (I32 0)) (ApplyComparisonOp LT (Ref __iruid_6628) (I32 5))))) (GetField sample_id (Ref __iruid_6626))))) (5_to_10 (ToSet (StreamMap __iruid_6629 (StreamFilter __iruid_6630 (ToStream False (Ref __iruid_6597)) (Let __iruid_6631 (GetField gq (Ref __iruid_6630)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6631) (I32 5)) (ApplyComparisonOp LT (Ref __iruid_6631) (I32 10))))) (GetField sample_id (Ref __iruid_6629))))) (10_to_15 (ToSet (StreamMap __iruid_6632 (StreamFilter __iruid_6633 (ToStream False (Ref __iruid_6597)) (Let __iruid_6634 (GetField gq (Ref __iruid_6633)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6634) (I32 10)) (ApplyComparisonOp LT (Ref __iruid_6634) (I32 15))))) (GetField sample_id (Ref __iruid_6632))))) (15_to_20 (ToSet (StreamMap __iruid_6635 (StreamFilter __iruid_6636 (ToStream False (Ref __iruid_6597)) (Let __iruid_6637 (GetField gq (Ref __iruid_6636)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6637) (I32 15)) (ApplyComparisonOp LT (Ref __iruid_6637) (I32 20))))) (GetField sample_id (Ref __iruid_6635))))) (20_to_25 (ToSet (StreamMap __iruid_6638 (StreamFilter __iruid_6639 (ToStream False (Ref __iruid_6597)) (Let __iruid_6640 (GetField gq (Ref __iruid_6639)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6640) (I32 20)) (ApplyComparisonOp LT (Ref __iruid_6640) (I32 25))))) (GetField sample_id (Ref __iruid_6638))))) (25_to_30 (ToSet (StreamMap __iruid_6641 (StreamFilter __iruid_6642 (ToStream False (Ref __iruid_6597)) (Let __iruid_6643 (GetField gq (Ref __iruid_6642)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6643) (I32 25)) (ApplyComparisonOp LT (Ref __iruid_6643) (I32 30))))) (GetField sample_id (Ref __iruid_6641))))) (30_to_35 (ToSet (StreamMap __iruid_6644 (StreamFilter __iruid_6645 (ToStream False (Ref __iruid_6597)) (Let __iruid_6646 (GetField gq (Ref __iruid_6645)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6646) (I32 30)) (ApplyComparisonOp LT (Ref __iruid_6646) (I32 35))))) (GetField sample_id (Ref __iruid_6644))))) (35_to_40 (ToSet (StreamMap __iruid_6647 (StreamFilter __iruid_6648 (ToStream False (Ref __iruid_6597)) (Let __iruid_6649 (GetField gq (Ref __iruid_6648)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6649) (I32 35)) (ApplyComparisonOp LT (Ref __iruid_6649) (I32 40))))) (GetField sample_id (Ref __iruid_6647))))) (40_to_45 (ToSet (StreamMap __iruid_6650 (StreamFilter __iruid_6651 (ToStream False (Ref __iruid_6597)) (Let __iruid_6652 (GetField gq (Ref __iruid_6651)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6652) (I32 40)) (ApplyComparisonOp LT (Ref __iruid_6652) (I32 45))))) (GetField sample_id (Ref __iruid_6650))))) (45_to_50 (ToSet (StreamMap __iruid_6653 (StreamFilter __iruid_6654 (ToStream False (Ref __iruid_6597)) (Let __iruid_6655 (GetField gq (Ref __iruid_6654)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6655) (I32 45)) (ApplyComparisonOp LT (Ref __iruid_6655) (I32 50))))) (GetField sample_id (Ref __iruid_6653))))) (50_to_55 (ToSet (StreamMap __iruid_6656 (StreamFilter __iruid_6657 (ToStream False (Ref __iruid_6597)) (Let __iruid_6658 (GetField gq (Ref __iruid_6657)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6658) (I32 50)) (ApplyComparisonOp LT (Ref __iruid_6658) (I32 55))))) (GetField sample_id (Ref __iruid_6656))))) (55_to_60 (ToSet (StreamMap __iruid_6659 (StreamFilter __iruid_6660 (ToStream False (Ref __iruid_6597)) (Let __iruid_6661 (GetField gq (Ref __iruid_6660)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6661) (I32 55)) (ApplyComparisonOp LT (Ref __iruid_6661) (I32 60))))) (GetField sample_id (Ref __iruid_6659))))) (60_to_65 (ToSet (StreamMap __iruid_6662 (StreamFilter __iruid_6663 (ToStream False (Ref __iruid_6597)) (Let __iruid_6664 (GetField gq (Ref __iruid_6663)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6664) (I32 60)) (ApplyComparisonOp LT (Ref __iruid_6664) (I32 65))))) (GetField sample_id (Ref __iruid_6662))))) (65_to_70 (ToSet (StreamMap __iruid_6665 (StreamFilter __iruid_6666 (ToStream False (Ref __iruid_6597)) (Let __iruid_6667 (GetField gq (Ref __iruid_6666)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6667) (I32 65)) (ApplyComparisonOp LT (Ref __iruid_6667) (I32 70))))) (GetField sample_id (Ref __iruid_6665))))) (70_to_75 (ToSet (StreamMap __iruid_6668 (StreamFilter __iruid_6669 (ToStream False (Ref __iruid_6597)) (Let __iruid_6670 (GetField gq (Ref __iruid_6669)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6670) (I32 70)) (ApplyComparisonOp LT (Ref __iruid_6670) (I32 75))))) (GetField sample_id (Ref __iruid_6668))))) (75_to_80 (ToSet (StreamMap __iruid_6671 (StreamFilter __iruid_6672 (ToStream False (Ref __iruid_6597)) (Let __iruid_6673 (GetField gq (Ref __iruid_6672)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6673) (I32 75)) (ApplyComparisonOp LT (Ref __iruid_6673) (I32 80))))) (GetField sample_id (Ref __iruid_6671))))) (80_to_85 (ToSet (StreamMap __iruid_6674 (StreamFilter __iruid_6675 (ToStream False (Ref __iruid_6597)) (Let __iruid_6676 (GetField gq (Ref __iruid_6675)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6676) (I32 80)) (ApplyComparisonOp LT (Ref __iruid_6676) (I32 85))))) (GetField sample_id (Ref __iruid_6674))))) (85_to_90 (ToSet (StreamMap __iruid_6677 (StreamFilter __iruid_6678 (ToStream False (Ref __iruid_6597)) (Let __iruid_6679 (GetField gq (Ref __iruid_6678)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6679) (I32 85)) (ApplyComparisonOp LT (Ref __iruid_6679) (I32 90))))) (GetField sample_id (Ref __iruid_6677))))) (90_to_95 (ToSet (StreamMap __iruid_6680 (StreamFilter __iruid_6681 (ToStream False (Ref __iruid_6597)) (Let __iruid_6682 (GetField gq (Ref __iruid_6681)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6682) (I32 90)) (ApplyComparisonOp LT (Ref __iruid_6682) (I32 95))))) (GetField sample_id (Ref __iruid_6680))))))) (samples_no_call (ToSet (StreamMap __iruid_6683 (StreamFilter __iruid_6684 (ToStream False (GetField genotypes (Ref __iruid_6595))) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6684)) (I32 -1))) (GetField sample_id (Ref __iruid_6683))))) (samples_num_alt (MakeStruct (1 (ToSet (StreamMap __iruid_6685 (StreamFilter __iruid_6686 (ToStream False (Ref __iruid_6598)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6686)) (I32 1))) (GetField sample_id (Ref __iruid_6685))))) (2 (ToSet (StreamMap __iruid_6687 (StreamFilter __iruid_6688 (ToStream False (Ref __iruid_6598)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6688)) (I32 2))) (GetField sample_id (Ref __iruid_6687)))))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.841ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 1.175ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 2.572ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 7.014ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.744ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 7.272ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 1.171ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.746ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 1.809ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 6.964ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 1.215ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 12.212ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 1.607ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 1.190ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 2.540ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 7.209ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 1.148ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 11.714ms, total 3m11.0s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 70.071ms, total 3m11.0s, tagged coverage 98.7 2022-04-01 03:28:28 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 624: (Coalesce (InsertFields (Let __iruid_6887 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)) (Let __iruid_6888 (GetField genotypes (Ref __iruid_6887)) (Let __iruid_6889 (GetField genotypes (Ref __iruid_6887)) (Let __iruid_6890 (GetField genotypes (Ref __iruid_6887)) (InsertFields (Ref __iruid_6887) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt") (primate_ai (GetField primate_ai (GetField __uid_48 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)))) (ref (ArrayRef (GetField alleles (Ref __iruid_6887)) (I32 0) (Str " File \"/h..."))) (rsid (GetField rsid (Ref __iruid_6887))) (samples_ab (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_6891 (StreamFilter __iruid_6892 (ToStream False (Ref __iruid_6888)) (Let __iruid_6893 (GetField ab (Ref __iruid_6892)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6892)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6893) (F64 100.0)) (F64 0.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6893) (F64 100.0)) (F64 5.0))))) (GetField sample_id (Ref __iruid_6891))))) (5_to_10 (ToSet (StreamMap __iruid_6894 (StreamFilter __iruid_6895 (ToStream False (Ref __iruid_6888)) (Let __iruid_6896 (GetField ab (Ref __iruid_6895)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6895)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6896) (F64 100.0)) (F64 5.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6896) (F64 100.0)) (F64 10.0))))) (GetField sample_id (Ref __iruid_6894))))) (10_to_15 (ToSet (StreamMap __iruid_6897 (StreamFilter __iruid_6898 (ToStream False (Ref __iruid_6888)) (Let __iruid_6899 (GetField ab (Ref __iruid_6898)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6898)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6899) (F64 100.0)) (F64 10.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6899) (F64 100.0)) (F64 15.0))))) (GetField sample_id (Ref __iruid_6897))))) (15_to_20 (ToSet (StreamMap __iruid_6900 (StreamFilter __iruid_6901 (ToStream False (Ref __iruid_6888)) (Let __iruid_6902 (GetField ab (Ref __iruid_6901)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6901)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6902) (F64 100.0)) (F64 15.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6902) (F64 100.0)) (F64 20.0))))) (GetField sample_id (Ref __iruid_6900))))) (20_to_25 (ToSet (StreamMap __iruid_6903 (StreamFilter __iruid_6904 (ToStream False (Ref __iruid_6888)) (Let __iruid_6905 (GetField ab (Ref __iruid_6904)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6904)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6905) (F64 100.0)) (F64 20.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6905) (F64 100.0)) (F64 25.0))))) (GetField sample_id (Ref __iruid_6903))))) (25_to_30 (ToSet (StreamMap __iruid_6906 (StreamFilter __iruid_6907 (ToStream False (Ref __iruid_6888)) (Let __iruid_6908 (GetField ab (Ref __iruid_6907)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6907)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6908) (F64 100.0)) (F64 25.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6908) (F64 100.0)) (F64 30.0))))) (GetField sample_id (Ref __iruid_6906))))) (30_to_35 (ToSet (StreamMap __iruid_6909 (StreamFilter __iruid_6910 (ToStream False (Ref __iruid_6888)) (Let __iruid_6911 (GetField ab (Ref __iruid_6910)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6910)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6911) (F64 100.0)) (F64 30.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6911) (F64 100.0)) (F64 35.0))))) (GetField sample_id (Ref __iruid_6909))))) (35_to_40 (ToSet (StreamMap __iruid_6912 (StreamFilter __iruid_6913 (ToStream False (Ref __iruid_6888)) (Let __iruid_6914 (GetField ab (Ref __iruid_6913)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6913)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6914) (F64 100.0)) (F64 35.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6914) (F64 100.0)) (F64 40.0))))) (GetField sample_id (Ref __iruid_6912))))) (40_to_45 (ToSet (StreamMap __iruid_6915 (StreamFilter __iruid_6916 (ToStream False (Ref __iruid_6888)) (Let __iruid_6917 (GetField ab (Ref __iruid_6916)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6916)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6917) (F64 100.0)) (F64 40.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6917) (F64 100.0)) (F64 45.0))))) (GetField sample_id (Ref __iruid_6915))))))) (samples_gq (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_6918 (StreamFilter __iruid_6919 (ToStream False (Ref __iruid_6889)) (Let __iruid_6920 (GetField gq (Ref __iruid_6919)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6920) (I32 0)) (ApplyComparisonOp LT (Ref __iruid_6920) (I32 5))))) (GetField sample_id (Ref __iruid_6918))))) (5_to_10 (ToSet (StreamMap __iruid_6921 (StreamFilter __iruid_6922 (ToStream False (Ref __iruid_6889)) (Let __iruid_6923 (GetField gq (Ref __iruid_6922)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6923) (I32 5)) (ApplyComparisonOp LT (Ref __iruid_6923) (I32 10))))) (GetField sample_id (Ref __iruid_6921))))) (10_to_15 (ToSet (StreamMap __iruid_6924 (StreamFilter __iruid_6925 (ToStream False (Ref __iruid_6889)) (Let __iruid_6926 (GetField gq (Ref __iruid_6925)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6926) (I32 10)) (ApplyComparisonOp LT (Ref __iruid_6926) (I32 15))))) (GetField sample_id (Ref __iruid_6924))))) (15_to_20 (ToSet (StreamMap __iruid_6927 (StreamFilter __iruid_6928 (ToStream False (Ref __iruid_6889)) (Let __iruid_6929 (GetField gq (Ref __iruid_6928)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6929) (I32 15)) (ApplyComparisonOp LT (Ref __iruid_6929) (I32 20))))) (GetField sample_id (Ref __iruid_6927))))) (20_to_25 (ToSet (StreamMap __iruid_6930 (StreamFilter __iruid_6931 (ToStream False (Ref __iruid_6889)) (Let __iruid_6932 (GetField gq (Ref __iruid_6931)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6932) (I32 20)) (ApplyComparisonOp LT (Ref __iruid_6932) (I32 25))))) (GetField sample_id (Ref __iruid_6930))))) (25_to_30 (ToSet (StreamMap __iruid_6933 (StreamFilter __iruid_6934 (ToStream False (Ref __iruid_6889)) (Let __iruid_6935 (GetField gq (Ref __iruid_6934)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6935) (I32 25)) (ApplyComparisonOp LT (Ref __iruid_6935) (I32 30))))) (GetField sample_id (Ref __iruid_6933))))) (30_to_35 (ToSet (StreamMap __iruid_6936 (StreamFilter __iruid_6937 (ToStream False (Ref __iruid_6889)) (Let __iruid_6938 (GetField gq (Ref __iruid_6937)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6938) (I32 30)) (ApplyComparisonOp LT (Ref __iruid_6938) (I32 35))))) (GetField sample_id (Ref __iruid_6936))))) (35_to_40 (ToSet (StreamMap __iruid_6939 (StreamFilter __iruid_6940 (ToStream False (Ref __iruid_6889)) (Let __iruid_6941 (GetField gq (Ref __iruid_6940)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6941) (I32 35)) (ApplyComparisonOp LT (Ref __iruid_6941) (I32 40))))) (GetField sample_id (Ref __iruid_6939))))) (40_to_45 (ToSet (StreamMap __iruid_6942 (StreamFilter __iruid_6943 (ToStream False (Ref __iruid_6889)) (Let __iruid_6944 (GetField gq (Ref __iruid_6943)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6944) (I32 40)) (ApplyComparisonOp LT (Ref __iruid_6944) (I32 45))))) (GetField sample_id (Ref __iruid_6942))))) (45_to_50 (ToSet (StreamMap __iruid_6945 (StreamFilter __iruid_6946 (ToStream False (Ref __iruid_6889)) (Let __iruid_6947 (GetField gq (Ref __iruid_6946)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6947) (I32 45)) (ApplyComparisonOp LT (Ref __iruid_6947) (I32 50))))) (GetField sample_id (Ref __iruid_6945))))) (50_to_55 (ToSet (StreamMap __iruid_6948 (StreamFilter __iruid_6949 (ToStream False (Ref __iruid_6889)) (Let __iruid_6950 (GetField gq (Ref __iruid_6949)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6950) (I32 50)) (ApplyComparisonOp LT (Ref __iruid_6950) (I32 55))))) (GetField sample_id (Ref __iruid_6948))))) (55_to_60 (ToSet (StreamMap __iruid_6951 (StreamFilter __iruid_6952 (ToStream False (Ref __iruid_6889)) (Let __iruid_6953 (GetField gq (Ref __iruid_6952)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6953) (I32 55)) (ApplyComparisonOp LT (Ref __iruid_6953) (I32 60))))) (GetField sample_id (Ref __iruid_6951))))) (60_to_65 (ToSet (StreamMap __iruid_6954 (StreamFilter __iruid_6955 (ToStream False (Ref __iruid_6889)) (Let __iruid_6956 (GetField gq (Ref __iruid_6955)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6956) (I32 60)) (ApplyComparisonOp LT (Ref __iruid_6956) (I32 65))))) (GetField sample_id (Ref __iruid_6954))))) (65_to_70 (ToSet (StreamMap __iruid_6957 (StreamFilter __iruid_6958 (ToStream False (Ref __iruid_6889)) (Let __iruid_6959 (GetField gq (Ref __iruid_6958)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6959) (I32 65)) (ApplyComparisonOp LT (Ref __iruid_6959) (I32 70))))) (GetField sample_id (Ref __iruid_6957))))) (70_to_75 (ToSet (StreamMap __iruid_6960 (StreamFilter __iruid_6961 (ToStream False (Ref __iruid_6889)) (Let __iruid_6962 (GetField gq (Ref __iruid_6961)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6962) (I32 70)) (ApplyComparisonOp LT (Ref __iruid_6962) (I32 75))))) (GetField sample_id (Ref __iruid_6960))))) (75_to_80 (ToSet (StreamMap __iruid_6963 (StreamFilter __iruid_6964 (ToStream False (Ref __iruid_6889)) (Let __iruid_6965 (GetField gq (Ref __iruid_6964)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6965) (I32 75)) (ApplyComparisonOp LT (Ref __iruid_6965) (I32 80))))) (GetField sample_id (Ref __iruid_6963))))) (80_to_85 (ToSet (StreamMap __iruid_6966 (StreamFilter __iruid_6967 (ToStream False (Ref __iruid_6889)) (Let __iruid_6968 (GetField gq (Ref __iruid_6967)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6968) (I32 80)) (ApplyComparisonOp LT (Ref __iruid_6968) (I32 85))))) (GetField sample_id (Ref __iruid_6966))))) (85_to_90 (ToSet (StreamMap __iruid_6969 (StreamFilter __iruid_6970 (ToStream False (Ref __iruid_6889)) (Let __iruid_6971 (GetField gq (Ref __iruid_6970)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6971) (I32 85)) (ApplyComparisonOp LT (Ref __iruid_6971) (I32 90))))) (GetField sample_id (Ref __iruid_6969))))) (90_to_95 (ToSet (StreamMap __iruid_6972 (StreamFilter __iruid_6973 (ToStream False (Ref __iruid_6889)) (Let __iruid_6974 (GetField gq (Ref __iruid_6973)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6974) (I32 90)) (ApplyComparisonOp LT (Ref __iruid_6974) (I32 95))))) (GetField sample_id (Ref __iruid_6972))))))) (samples_no_call (ToSet (StreamMap __iruid_6975 (StreamFilter __iruid_6976 (ToStream False (GetField genotypes (Ref __iruid_6887))) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6976)) (I32 -1))) (GetField sample_id (Ref __iruid_6975))))) (samples_num_alt (MakeStruct (1 (ToSet (StreamMap __iruid_6977 (StreamFilter __iruid_6978 (ToStream False (Ref __iruid_6890)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6978)) (I32 1))) (GetField sample_id (Ref __iruid_6977))))) (2 (ToSet (StreamMap __iruid_6979 (StreamFilter __iruid_6980 (ToStream False (Ref __iruid_6890)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6980)) (I32 2))) (GetField sample_id (Ref __iruid_6979)))))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 79.908ms, total 3m11.1s, tagged coverage 86.5 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.040ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 80.102ms, total 3m11.1s, tagged coverage 86.4 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.182ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 24.248ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.149ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 24.736ms, total 3m11.1s, tagged coverage 99.4 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.022ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 624: (Coalesce (InsertFields (Let __iruid_6887 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)) (Let __iruid_6888 (GetField genotypes (Ref __iruid_6887)) (Let __iruid_6889 (GetField genotypes (Ref __iruid_6887)) (Let __iruid_6890 (GetField genotypes (Ref __iruid_6887)) (InsertFields (Ref __iruid_6887) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt") (primate_ai (GetField primate_ai (GetField __uid_48 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)))) (ref (ArrayRef (GetField alleles (Ref __iruid_6887)) (I32 0) (Str " File \"/h..."))) (rsid (GetField rsid (Ref __iruid_6887))) (samples_ab (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_6891 (StreamFilter __iruid_6892 (ToStream False (Ref __iruid_6888)) (Let __iruid_6893 (GetField ab (Ref __iruid_6892)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6892)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6893) (F64 100.0)) (F64 0.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6893) (F64 100.0)) (F64 5.0))))) (GetField sample_id (Ref __iruid_6891))))) (5_to_10 (ToSet (StreamMap __iruid_6894 (StreamFilter __iruid_6895 (ToStream False (Ref __iruid_6888)) (Let __iruid_6896 (GetField ab (Ref __iruid_6895)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6895)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6896) (F64 100.0)) (F64 5.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6896) (F64 100.0)) (F64 10.0))))) (GetField sample_id (Ref __iruid_6894))))) (10_to_15 (ToSet (StreamMap __iruid_6897 (StreamFilter __iruid_6898 (ToStream False (Ref __iruid_6888)) (Let __iruid_6899 (GetField ab (Ref __iruid_6898)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6898)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6899) (F64 100.0)) (F64 10.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6899) (F64 100.0)) (F64 15.0))))) (GetField sample_id (Ref __iruid_6897))))) (15_to_20 (ToSet (StreamMap __iruid_6900 (StreamFilter __iruid_6901 (ToStream False (Ref __iruid_6888)) (Let __iruid_6902 (GetField ab (Ref __iruid_6901)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6901)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6902) (F64 100.0)) (F64 15.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6902) (F64 100.0)) (F64 20.0))))) (GetField sample_id (Ref __iruid_6900))))) (20_to_25 (ToSet (StreamMap __iruid_6903 (StreamFilter __iruid_6904 (ToStream False (Ref __iruid_6888)) (Let __iruid_6905 (GetField ab (Ref __iruid_6904)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6904)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6905) (F64 100.0)) (F64 20.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6905) (F64 100.0)) (F64 25.0))))) (GetField sample_id (Ref __iruid_6903))))) (25_to_30 (ToSet (StreamMap __iruid_6906 (StreamFilter __iruid_6907 (ToStream False (Ref __iruid_6888)) (Let __iruid_6908 (GetField ab (Ref __iruid_6907)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6907)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6908) (F64 100.0)) (F64 25.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6908) (F64 100.0)) (F64 30.0))))) (GetField sample_id (Ref __iruid_6906))))) (30_to_35 (ToSet (StreamMap __iruid_6909 (StreamFilter __iruid_6910 (ToStream False (Ref __iruid_6888)) (Let __iruid_6911 (GetField ab (Ref __iruid_6910)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6910)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6911) (F64 100.0)) (F64 30.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6911) (F64 100.0)) (F64 35.0))))) (GetField sample_id (Ref __iruid_6909))))) (35_to_40 (ToSet (StreamMap __iruid_6912 (StreamFilter __iruid_6913 (ToStream False (Ref __iruid_6888)) (Let __iruid_6914 (GetField ab (Ref __iruid_6913)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6913)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6914) (F64 100.0)) (F64 35.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6914) (F64 100.0)) (F64 40.0))))) (GetField sample_id (Ref __iruid_6912))))) (40_to_45 (ToSet (StreamMap __iruid_6915 (StreamFilter __iruid_6916 (ToStream False (Ref __iruid_6888)) (Let __iruid_6917 (GetField ab (Ref __iruid_6916)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6916)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_6917) (F64 100.0)) (F64 40.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_6917) (F64 100.0)) (F64 45.0))))) (GetField sample_id (Ref __iruid_6915))))))) (samples_gq (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_6918 (StreamFilter __iruid_6919 (ToStream False (Ref __iruid_6889)) (Let __iruid_6920 (GetField gq (Ref __iruid_6919)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6920) (I32 0)) (ApplyComparisonOp LT (Ref __iruid_6920) (I32 5))))) (GetField sample_id (Ref __iruid_6918))))) (5_to_10 (ToSet (StreamMap __iruid_6921 (StreamFilter __iruid_6922 (ToStream False (Ref __iruid_6889)) (Let __iruid_6923 (GetField gq (Ref __iruid_6922)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6923) (I32 5)) (ApplyComparisonOp LT (Ref __iruid_6923) (I32 10))))) (GetField sample_id (Ref __iruid_6921))))) (10_to_15 (ToSet (StreamMap __iruid_6924 (StreamFilter __iruid_6925 (ToStream False (Ref __iruid_6889)) (Let __iruid_6926 (GetField gq (Ref __iruid_6925)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6926) (I32 10)) (ApplyComparisonOp LT (Ref __iruid_6926) (I32 15))))) (GetField sample_id (Ref __iruid_6924))))) (15_to_20 (ToSet (StreamMap __iruid_6927 (StreamFilter __iruid_6928 (ToStream False (Ref __iruid_6889)) (Let __iruid_6929 (GetField gq (Ref __iruid_6928)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6929) (I32 15)) (ApplyComparisonOp LT (Ref __iruid_6929) (I32 20))))) (GetField sample_id (Ref __iruid_6927))))) (20_to_25 (ToSet (StreamMap __iruid_6930 (StreamFilter __iruid_6931 (ToStream False (Ref __iruid_6889)) (Let __iruid_6932 (GetField gq (Ref __iruid_6931)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6932) (I32 20)) (ApplyComparisonOp LT (Ref __iruid_6932) (I32 25))))) (GetField sample_id (Ref __iruid_6930))))) (25_to_30 (ToSet (StreamMap __iruid_6933 (StreamFilter __iruid_6934 (ToStream False (Ref __iruid_6889)) (Let __iruid_6935 (GetField gq (Ref __iruid_6934)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6935) (I32 25)) (ApplyComparisonOp LT (Ref __iruid_6935) (I32 30))))) (GetField sample_id (Ref __iruid_6933))))) (30_to_35 (ToSet (StreamMap __iruid_6936 (StreamFilter __iruid_6937 (ToStream False (Ref __iruid_6889)) (Let __iruid_6938 (GetField gq (Ref __iruid_6937)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6938) (I32 30)) (ApplyComparisonOp LT (Ref __iruid_6938) (I32 35))))) (GetField sample_id (Ref __iruid_6936))))) (35_to_40 (ToSet (StreamMap __iruid_6939 (StreamFilter __iruid_6940 (ToStream False (Ref __iruid_6889)) (Let __iruid_6941 (GetField gq (Ref __iruid_6940)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6941) (I32 35)) (ApplyComparisonOp LT (Ref __iruid_6941) (I32 40))))) (GetField sample_id (Ref __iruid_6939))))) (40_to_45 (ToSet (StreamMap __iruid_6942 (StreamFilter __iruid_6943 (ToStream False (Ref __iruid_6889)) (Let __iruid_6944 (GetField gq (Ref __iruid_6943)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6944) (I32 40)) (ApplyComparisonOp LT (Ref __iruid_6944) (I32 45))))) (GetField sample_id (Ref __iruid_6942))))) (45_to_50 (ToSet (StreamMap __iruid_6945 (StreamFilter __iruid_6946 (ToStream False (Ref __iruid_6889)) (Let __iruid_6947 (GetField gq (Ref __iruid_6946)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6947) (I32 45)) (ApplyComparisonOp LT (Ref __iruid_6947) (I32 50))))) (GetField sample_id (Ref __iruid_6945))))) (50_to_55 (ToSet (StreamMap __iruid_6948 (StreamFilter __iruid_6949 (ToStream False (Ref __iruid_6889)) (Let __iruid_6950 (GetField gq (Ref __iruid_6949)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6950) (I32 50)) (ApplyComparisonOp LT (Ref __iruid_6950) (I32 55))))) (GetField sample_id (Ref __iruid_6948))))) (55_to_60 (ToSet (StreamMap __iruid_6951 (StreamFilter __iruid_6952 (ToStream False (Ref __iruid_6889)) (Let __iruid_6953 (GetField gq (Ref __iruid_6952)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6953) (I32 55)) (ApplyComparisonOp LT (Ref __iruid_6953) (I32 60))))) (GetField sample_id (Ref __iruid_6951))))) (60_to_65 (ToSet (StreamMap __iruid_6954 (StreamFilter __iruid_6955 (ToStream False (Ref __iruid_6889)) (Let __iruid_6956 (GetField gq (Ref __iruid_6955)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6956) (I32 60)) (ApplyComparisonOp LT (Ref __iruid_6956) (I32 65))))) (GetField sample_id (Ref __iruid_6954))))) (65_to_70 (ToSet (StreamMap __iruid_6957 (StreamFilter __iruid_6958 (ToStream False (Ref __iruid_6889)) (Let __iruid_6959 (GetField gq (Ref __iruid_6958)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6959) (I32 65)) (ApplyComparisonOp LT (Ref __iruid_6959) (I32 70))))) (GetField sample_id (Ref __iruid_6957))))) (70_to_75 (ToSet (StreamMap __iruid_6960 (StreamFilter __iruid_6961 (ToStream False (Ref __iruid_6889)) (Let __iruid_6962 (GetField gq (Ref __iruid_6961)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6962) (I32 70)) (ApplyComparisonOp LT (Ref __iruid_6962) (I32 75))))) (GetField sample_id (Ref __iruid_6960))))) (75_to_80 (ToSet (StreamMap __iruid_6963 (StreamFilter __iruid_6964 (ToStream False (Ref __iruid_6889)) (Let __iruid_6965 (GetField gq (Ref __iruid_6964)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6965) (I32 75)) (ApplyComparisonOp LT (Ref __iruid_6965) (I32 80))))) (GetField sample_id (Ref __iruid_6963))))) (80_to_85 (ToSet (StreamMap __iruid_6966 (StreamFilter __iruid_6967 (ToStream False (Ref __iruid_6889)) (Let __iruid_6968 (GetField gq (Ref __iruid_6967)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6968) (I32 80)) (ApplyComparisonOp LT (Ref __iruid_6968) (I32 85))))) (GetField sample_id (Ref __iruid_6966))))) (85_to_90 (ToSet (StreamMap __iruid_6969 (StreamFilter __iruid_6970 (ToStream False (Ref __iruid_6889)) (Let __iruid_6971 (GetField gq (Ref __iruid_6970)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6971) (I32 85)) (ApplyComparisonOp LT (Ref __iruid_6971) (I32 90))))) (GetField sample_id (Ref __iruid_6969))))) (90_to_95 (ToSet (StreamMap __iruid_6972 (StreamFilter __iruid_6973 (ToStream False (Ref __iruid_6889)) (Let __iruid_6974 (GetField gq (Ref __iruid_6973)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_6974) (I32 90)) (ApplyComparisonOp LT (Ref __iruid_6974) (I32 95))))) (GetField sample_id (Ref __iruid_6972))))))) (samples_no_call (ToSet (StreamMap __iruid_6975 (StreamFilter __iruid_6976 (ToStream False (GetField genotypes (Ref __iruid_6887))) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6976)) (I32 -1))) (GetField sample_id (Ref __iruid_6975))))) (samples_num_alt (MakeStruct (1 (ToSet (StreamMap __iruid_6977 (StreamFilter __iruid_6978 (ToStream False (Ref __iruid_6890)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6978)) (I32 1))) (GetField sample_id (Ref __iruid_6977))))) (2 (ToSet (StreamMap __iruid_6979 (StreamFilter __iruid_6980 (ToStream False (Ref __iruid_6890)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_6980)) (I32 2))) (GetField sample_id (Ref __iruid_6979)))))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.790ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 1.199ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 2.519ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 7.209ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.969ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 11.523ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 1.600ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 1.221ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 2.533ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 7.205ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 1.218ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 11.614ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 1.567ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 1.186ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 2.538ms, total 3m11.1s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 7.291ms, total 3m11.2s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 1.230ms, total 3m11.2s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 11.435ms, total 3m11.2s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 75.765ms, total 3m11.2s, tagged coverage 98.8 2022-04-01 03:28:28 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 624: (Coalesce (InsertFields (Let __iruid_7169 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)) (Let __iruid_7170 (GetField genotypes (Ref __iruid_7169)) (Let __iruid_7171 (GetField genotypes (Ref __iruid_7169)) (Let __iruid_7172 (GetField genotypes (Ref __iruid_7169)) (InsertFields (Ref __iruid_7169) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt") (primate_ai (GetField primate_ai (GetField __uid_48 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)))) (ref (ArrayRef (GetField alleles (Ref __iruid_7169)) (I32 0) (Str " File \"/h..."))) (rsid (GetField rsid (Ref __iruid_7169))) (samples_ab (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_7173 (StreamFilter __iruid_7174 (ToStream False (Ref __iruid_7170)) (Let __iruid_7175 (GetField ab (Ref __iruid_7174)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_7174)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_7175) (F64 100.0)) (F64 0.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_7175) (F64 100.0)) (F64 5.0))))) (GetField sample_id (Ref __iruid_7173))))) (5_to_10 (ToSet (StreamMap __iruid_7176 (StreamFilter __iruid_7177 (ToStream False (Ref __iruid_7170)) (Let __iruid_7178 (GetField ab (Ref __iruid_7177)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_7177)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_7178) (F64 100.0)) (F64 5.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_7178) (F64 100.0)) (F64 10.0))))) (GetField sample_id (Ref __iruid_7176))))) (10_to_15 (ToSet (StreamMap __iruid_7179 (StreamFilter __iruid_7180 (ToStream False (Ref __iruid_7170)) (Let __iruid_7181 (GetField ab (Ref __iruid_7180)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_7180)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_7181) (F64 100.0)) (F64 10.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_7181) (F64 100.0)) (F64 15.0))))) (GetField sample_id (Ref __iruid_7179))))) (15_to_20 (ToSet (StreamMap __iruid_7182 (StreamFilter __iruid_7183 (ToStream False (Ref __iruid_7170)) (Let __iruid_7184 (GetField ab (Ref __iruid_7183)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_7183)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_7184) (F64 100.0)) (F64 15.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_7184) (F64 100.0)) (F64 20.0))))) (GetField sample_id (Ref __iruid_7182))))) (20_to_25 (ToSet (StreamMap __iruid_7185 (StreamFilter __iruid_7186 (ToStream False (Ref __iruid_7170)) (Let __iruid_7187 (GetField ab (Ref __iruid_7186)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_7186)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_7187) (F64 100.0)) (F64 20.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_7187) (F64 100.0)) (F64 25.0))))) (GetField sample_id (Ref __iruid_7185))))) (25_to_30 (ToSet (StreamMap __iruid_7188 (StreamFilter __iruid_7189 (ToStream False (Ref __iruid_7170)) (Let __iruid_7190 (GetField ab (Ref __iruid_7189)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_7189)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_7190) (F64 100.0)) (F64 25.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_7190) (F64 100.0)) (F64 30.0))))) (GetField sample_id (Ref __iruid_7188))))) (30_to_35 (ToSet (StreamMap __iruid_7191 (StreamFilter __iruid_7192 (ToStream False (Ref __iruid_7170)) (Let __iruid_7193 (GetField ab (Ref __iruid_7192)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_7192)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_7193) (F64 100.0)) (F64 30.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_7193) (F64 100.0)) (F64 35.0))))) (GetField sample_id (Ref __iruid_7191))))) (35_to_40 (ToSet (StreamMap __iruid_7194 (StreamFilter __iruid_7195 (ToStream False (Ref __iruid_7170)) (Let __iruid_7196 (GetField ab (Ref __iruid_7195)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_7195)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_7196) (F64 100.0)) (F64 35.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_7196) (F64 100.0)) (F64 40.0))))) (GetField sample_id (Ref __iruid_7194))))) (40_to_45 (ToSet (StreamMap __iruid_7197 (StreamFilter __iruid_7198 (ToStream False (Ref __iruid_7170)) (Let __iruid_7199 (GetField ab (Ref __iruid_7198)) (ApplySpecial land () Boolean (ApplySpecial land () Boolean (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_7198)) (I32 1)) (ApplyComparisonOp GTEQ (ApplyBinaryPrimOp Multiply (Ref __iruid_7199) (F64 100.0)) (F64 40.0))) (ApplyComparisonOp LT (ApplyBinaryPrimOp Multiply (Ref __iruid_7199) (F64 100.0)) (F64 45.0))))) (GetField sample_id (Ref __iruid_7197))))))) (samples_gq (MakeStruct (0_to_5 (ToSet (StreamMap __iruid_7200 (StreamFilter __iruid_7201 (ToStream False (Ref __iruid_7171)) (Let __iruid_7202 (GetField gq (Ref __iruid_7201)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7202) (I32 0)) (ApplyComparisonOp LT (Ref __iruid_7202) (I32 5))))) (GetField sample_id (Ref __iruid_7200))))) (5_to_10 (ToSet (StreamMap __iruid_7203 (StreamFilter __iruid_7204 (ToStream False (Ref __iruid_7171)) (Let __iruid_7205 (GetField gq (Ref __iruid_7204)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7205) (I32 5)) (ApplyComparisonOp LT (Ref __iruid_7205) (I32 10))))) (GetField sample_id (Ref __iruid_7203))))) (10_to_15 (ToSet (StreamMap __iruid_7206 (StreamFilter __iruid_7207 (ToStream False (Ref __iruid_7171)) (Let __iruid_7208 (GetField gq (Ref __iruid_7207)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7208) (I32 10)) (ApplyComparisonOp LT (Ref __iruid_7208) (I32 15))))) (GetField sample_id (Ref __iruid_7206))))) (15_to_20 (ToSet (StreamMap __iruid_7209 (StreamFilter __iruid_7210 (ToStream False (Ref __iruid_7171)) (Let __iruid_7211 (GetField gq (Ref __iruid_7210)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7211) (I32 15)) (ApplyComparisonOp LT (Ref __iruid_7211) (I32 20))))) (GetField sample_id (Ref __iruid_7209))))) (20_to_25 (ToSet (StreamMap __iruid_7212 (StreamFilter __iruid_7213 (ToStream False (Ref __iruid_7171)) (Let __iruid_7214 (GetField gq (Ref __iruid_7213)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7214) (I32 20)) (ApplyComparisonOp LT (Ref __iruid_7214) (I32 25))))) (GetField sample_id (Ref __iruid_7212))))) (25_to_30 (ToSet (StreamMap __iruid_7215 (StreamFilter __iruid_7216 (ToStream False (Ref __iruid_7171)) (Let __iruid_7217 (GetField gq (Ref __iruid_7216)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7217) (I32 25)) (ApplyComparisonOp LT (Ref __iruid_7217) (I32 30))))) (GetField sample_id (Ref __iruid_7215))))) (30_to_35 (ToSet (StreamMap __iruid_7218 (StreamFilter __iruid_7219 (ToStream False (Ref __iruid_7171)) (Let __iruid_7220 (GetField gq (Ref __iruid_7219)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7220) (I32 30)) (ApplyComparisonOp LT (Ref __iruid_7220) (I32 35))))) (GetField sample_id (Ref __iruid_7218))))) (35_to_40 (ToSet (StreamMap __iruid_7221 (StreamFilter __iruid_7222 (ToStream False (Ref __iruid_7171)) (Let __iruid_7223 (GetField gq (Ref __iruid_7222)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7223) (I32 35)) (ApplyComparisonOp LT (Ref __iruid_7223) (I32 40))))) (GetField sample_id (Ref __iruid_7221))))) (40_to_45 (ToSet (StreamMap __iruid_7224 (StreamFilter __iruid_7225 (ToStream False (Ref __iruid_7171)) (Let __iruid_7226 (GetField gq (Ref __iruid_7225)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7226) (I32 40)) (ApplyComparisonOp LT (Ref __iruid_7226) (I32 45))))) (GetField sample_id (Ref __iruid_7224))))) (45_to_50 (ToSet (StreamMap __iruid_7227 (StreamFilter __iruid_7228 (ToStream False (Ref __iruid_7171)) (Let __iruid_7229 (GetField gq (Ref __iruid_7228)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7229) (I32 45)) (ApplyComparisonOp LT (Ref __iruid_7229) (I32 50))))) (GetField sample_id (Ref __iruid_7227))))) (50_to_55 (ToSet (StreamMap __iruid_7230 (StreamFilter __iruid_7231 (ToStream False (Ref __iruid_7171)) (Let __iruid_7232 (GetField gq (Ref __iruid_7231)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7232) (I32 50)) (ApplyComparisonOp LT (Ref __iruid_7232) (I32 55))))) (GetField sample_id (Ref __iruid_7230))))) (55_to_60 (ToSet (StreamMap __iruid_7233 (StreamFilter __iruid_7234 (ToStream False (Ref __iruid_7171)) (Let __iruid_7235 (GetField gq (Ref __iruid_7234)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7235) (I32 55)) (ApplyComparisonOp LT (Ref __iruid_7235) (I32 60))))) (GetField sample_id (Ref __iruid_7233))))) (60_to_65 (ToSet (StreamMap __iruid_7236 (StreamFilter __iruid_7237 (ToStream False (Ref __iruid_7171)) (Let __iruid_7238 (GetField gq (Ref __iruid_7237)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7238) (I32 60)) (ApplyComparisonOp LT (Ref __iruid_7238) (I32 65))))) (GetField sample_id (Ref __iruid_7236))))) (65_to_70 (ToSet (StreamMap __iruid_7239 (StreamFilter __iruid_7240 (ToStream False (Ref __iruid_7171)) (Let __iruid_7241 (GetField gq (Ref __iruid_7240)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7241) (I32 65)) (ApplyComparisonOp LT (Ref __iruid_7241) (I32 70))))) (GetField sample_id (Ref __iruid_7239))))) (70_to_75 (ToSet (StreamMap __iruid_7242 (StreamFilter __iruid_7243 (ToStream False (Ref __iruid_7171)) (Let __iruid_7244 (GetField gq (Ref __iruid_7243)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7244) (I32 70)) (ApplyComparisonOp LT (Ref __iruid_7244) (I32 75))))) (GetField sample_id (Ref __iruid_7242))))) (75_to_80 (ToSet (StreamMap __iruid_7245 (StreamFilter __iruid_7246 (ToStream False (Ref __iruid_7171)) (Let __iruid_7247 (GetField gq (Ref __iruid_7246)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7247) (I32 75)) (ApplyComparisonOp LT (Ref __iruid_7247) (I32 80))))) (GetField sample_id (Ref __iruid_7245))))) (80_to_85 (ToSet (StreamMap __iruid_7248 (StreamFilter __iruid_7249 (ToStream False (Ref __iruid_7171)) (Let __iruid_7250 (GetField gq (Ref __iruid_7249)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7250) (I32 80)) (ApplyComparisonOp LT (Ref __iruid_7250) (I32 85))))) (GetField sample_id (Ref __iruid_7248))))) (85_to_90 (ToSet (StreamMap __iruid_7251 (StreamFilter __iruid_7252 (ToStream False (Ref __iruid_7171)) (Let __iruid_7253 (GetField gq (Ref __iruid_7252)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7253) (I32 85)) (ApplyComparisonOp LT (Ref __iruid_7253) (I32 90))))) (GetField sample_id (Ref __iruid_7251))))) (90_to_95 (ToSet (StreamMap __iruid_7254 (StreamFilter __iruid_7255 (ToStream False (Ref __iruid_7171)) (Let __iruid_7256 (GetField gq (Ref __iruid_7255)) (ApplySpecial land () Boolean (ApplyComparisonOp GTEQ (Ref __iruid_7256) (I32 90)) (ApplyComparisonOp LT (Ref __iruid_7256) (I32 95))))) (GetField sample_id (Ref __iruid_7254))))))) (samples_no_call (ToSet (StreamMap __iruid_7257 (StreamFilter __iruid_7258 (ToStream False (GetField genotypes (Ref __iruid_7169))) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_7258)) (I32 -1))) (GetField sample_id (Ref __iruid_7257))))) (samples_num_alt (MakeStruct (1 (ToSet (StreamMap __iruid_7259 (StreamFilter __iruid_7260 (ToStream False (Ref __iruid_7172)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_7260)) (I32 1))) (GetField sample_id (Ref __iruid_7259))))) (2 (ToSet (StreamMap __iruid_7261 (StreamFilter __iruid_7262 (ToStream False (Ref __iruid_7172)) (ApplyComparisonOp EQ (GetField num_alt (Ref __iruid_7262)) (I32 2))) (GetField sample_id (Ref __iruid_7261)))))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],alleles_old:+PCArray[+PCString],locus_old:+PCLocus(GRCh38),vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_48:PCStruct{primate_ai:PCStruct{score:PFloat64}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 84.793ms, total 3m11.2s, tagged coverage 88.3 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.034ms, total 3m11.2s 2022-04-01 03:28:28 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 84.982ms, total 3m11.2s, tagged coverage 88.1 2022-04-01 03:28:28 root: INFO: encoder cache hit 2022-04-01 03:28:28 MemoryStore: INFO: Block broadcast_27 stored as values in memory (estimated size 104.0 B, free 5.6 GB) 2022-04-01 03:28:28 MemoryStore: INFO: Block broadcast_27_piece0 stored as bytes in memory (estimated size 109.0 B, free 5.6 GB) 2022-04-01 03:28:28 BlockManagerInfo: INFO: Added broadcast_27_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 109.0 B, free: 5.6 GB) 2022-04-01 03:28:28 SparkContext: INFO: Created broadcast 27 from broadcast at SparkBackend.scala:233 2022-04-01 03:28:28 root: INFO: instruction count: 6: __C2239Compiled. 2022-04-01 03:28:28 root: INFO: instruction count: 440: __C2239Compiled.apply 2022-04-01 03:28:28 root: INFO: instruction count: 11: __C2239Compiled.__m2245addIRIntermediate 2022-04-01 03:28:28 root: INFO: instruction count: 8: __C2239Compiled.__m2246addIRIntermediate 2022-04-01 03:28:28 root: INFO: instruction count: 8: __C2239Compiled.__m2247addIRIntermediate 2022-04-01 03:28:28 root: INFO: instruction count: 8: __C2239Compiled.__m2248addIRIntermediate 2022-04-01 03:28:28 root: INFO: instruction count: 11: 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__C2239Compiled.__m2860setup_jab 2022-04-01 03:28:28 root: INFO: instruction count: 50: __C2239Compiled.__m2861discardNext 2022-04-01 03:28:28 root: INFO: instruction count: 11: __C2239Compiled.__m2879addIRIntermediate 2022-04-01 03:28:28 root: INFO: instruction count: 15: __C2239Compiled.__m2882setup_jab 2022-04-01 03:28:28 root: INFO: instruction count: 50: __C2239Compiled.__m2883discardNext 2022-04-01 03:28:28 root: INFO: instruction count: 15: __C2239Compiled.__m2903setup_jab 2022-04-01 03:28:28 root: INFO: instruction count: 50: __C2239Compiled.__m2904discardNext 2022-04-01 03:28:28 root: INFO: instruction count: 15: __C2239Compiled.__m2922setup_jab 2022-04-01 03:28:28 root: INFO: instruction count: 50: __C2239Compiled.__m2923discardNext 2022-04-01 03:28:28 root: INFO: instruction count: 11: __C2239Compiled.__m2939addIRIntermediate 2022-04-01 03:28:28 root: INFO: instruction count: 8: __C2239Compiled.__m2943addIRIntermediate 2022-04-01 03:28:28 root: INFO: instruction count: 14: __C2239Compiled.setPartitionIndex 2022-04-01 03:28:28 root: INFO: instruction count: 7: __C2239Compiled.addPartitionRegion 2022-04-01 03:28:28 root: INFO: instruction count: 25: __C2239Compiled.__m2947DECODE_r_struct_of_r_binaryEND_TO_r_tuple_of_r_stringEND 2022-04-01 03:28:28 root: INFO: instruction count: 11: __C2239Compiled.__m2948read_fields_group_0 2022-04-01 03:28:28 root: INFO: instruction count: 34: __C2239Compiled.__m2949INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:28:28 root: INFO: instruction count: 41: __C2239Compiled.addLiterals 2022-04-01 03:28:28 root: INFO: instruction count: 217: __C2239Compiled.applyregion2177_2184 2022-04-01 03:28:28 root: INFO: instruction count: 198: __C2239Compiled.applyregion2080_2096 2022-04-01 03:28:28 root: INFO: instruction count: 106: __C2239Compiled.applyregion2121_2128 2022-04-01 03:28:28 root: INFO: instruction count: 102: __C2239Compiled.applyregion2105_2112 2022-04-01 03:28:28 root: INFO: instruction count: 102: 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count: 268: __C2239Compiled.applyregion654_696 2022-04-01 03:28:28 root: INFO: instruction count: 270: __C2239Compiled.applyregion545_588 2022-04-01 03:28:28 root: INFO: instruction count: 656: __C2239Compiled.applyregion541_3233 2022-04-01 03:28:28 root: INFO: instruction count: 311: __C2239Compiled.applyregion431_475 2022-04-01 03:28:28 root: INFO: instruction count: 576: __C2239Compiled.applyregion421_3234 2022-04-01 03:28:28 root: INFO: instruction count: 475: __C2239Compiled.applyregion370_3248 2022-04-01 03:28:28 root: INFO: instruction count: 311: __C2239Compiled.applyregion259_303 2022-04-01 03:28:28 root: INFO: instruction count: 270: __C2239Compiled.applyregion304_347 2022-04-01 03:28:28 root: INFO: instruction count: 270: __C2239Compiled.applyregion193_236 2022-04-01 03:28:28 root: INFO: instruction count: 223: __C2239Compiled.applyregion370_3285 2022-04-01 03:28:28 root: INFO: instruction count: 543: __C2239Compiled.applyregion189_3290 2022-04-01 03:28:28 root: INFO: instruction count: 427: __C2239Compiled.applyregion176_3328 2022-04-01 03:28:28 root: INFO: instruction count: 281: __C2239Compiled.applyregion80_87 2022-04-01 03:28:28 root: INFO: instruction count: 152: __C2239Compiled.applyregion0_7 2022-04-01 03:28:28 root: INFO: instruction count: 122: __C2239Compiled.applyregion120_127 2022-04-01 03:28:28 root: INFO: instruction count: 122: __C2239Compiled.applyregion32_39 2022-04-01 03:28:28 root: INFO: instruction count: 120: __C2239Compiled.applyregion168_175 2022-04-01 03:28:28 root: INFO: instruction count: 102: __C2239Compiled.applyregion104_111 2022-04-01 03:28:28 root: INFO: instruction count: 102: __C2239Compiled.applyregion16_23 2022-04-01 03:28:28 root: INFO: instruction count: 102: __C2239Compiled.applyregion144_151 2022-04-01 03:28:28 root: INFO: instruction count: 102: __C2239Compiled.applyregion56_63 2022-04-01 03:28:28 root: INFO: instruction count: 100: __C2239Compiled.applyregion128_135 2022-04-01 03:28:28 root: INFO: 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03:28:29 root: INFO: instruction count: 26: __C2374sort_compare.__m2377cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2374sort_compare.__m2378cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2395sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2395sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2395sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2395sort_compare.__m2397sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2395sort_compare.__m2398cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2395sort_compare.__m2399cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2416sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2416sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2416sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2416sort_compare.__m2418sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2416sort_compare.__m2419cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2416sort_compare.__m2420cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2437sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2437sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2437sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2437sort_compare.__m2439sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2437sort_compare.__m2440cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2437sort_compare.__m2441cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2458sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2458sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2458sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2458sort_compare.__m2460sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2458sort_compare.__m2461cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2458sort_compare.__m2462cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2482sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2482sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2482sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2482sort_compare.__m2484sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2482sort_compare.__m2485cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2482sort_compare.__m2486cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2505sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2505sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2505sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2505sort_compare.__m2507sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2505sort_compare.__m2508cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2505sort_compare.__m2509cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2526sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2526sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2526sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2526sort_compare.__m2528sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2526sort_compare.__m2529cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2526sort_compare.__m2530cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2547sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2547sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2547sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2547sort_compare.__m2549sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2547sort_compare.__m2550cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2547sort_compare.__m2551cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2568sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2568sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2568sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2568sort_compare.__m2570sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2568sort_compare.__m2571cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2568sort_compare.__m2572cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2589sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2589sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2589sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2589sort_compare.__m2591sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2589sort_compare.__m2592cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2589sort_compare.__m2593cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2610sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2610sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2610sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2610sort_compare.__m2612sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2610sort_compare.__m2613cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2610sort_compare.__m2614cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2631sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2631sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2631sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2631sort_compare.__m2633sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2631sort_compare.__m2634cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2631sort_compare.__m2635cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2652sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2652sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2652sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2652sort_compare.__m2654sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2652sort_compare.__m2655cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2652sort_compare.__m2656cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2673sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2673sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2673sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2673sort_compare.__m2675sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2673sort_compare.__m2676cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2673sort_compare.__m2677cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2694sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2694sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2694sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2694sort_compare.__m2696sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2694sort_compare.__m2697cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2694sort_compare.__m2698cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2715sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2715sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2715sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2715sort_compare.__m2717sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2715sort_compare.__m2718cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2715sort_compare.__m2719cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2736sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2736sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2736sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2736sort_compare.__m2738sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2736sort_compare.__m2739cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2736sort_compare.__m2740cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2757sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2757sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2757sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2757sort_compare.__m2759sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2757sort_compare.__m2760cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2757sort_compare.__m2761cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2778sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2778sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2778sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2778sort_compare.__m2780sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2778sort_compare.__m2781cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2778sort_compare.__m2782cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2799sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2799sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2799sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2799sort_compare.__m2801sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2799sort_compare.__m2802cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2799sort_compare.__m2803cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2820sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2820sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2820sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2820sort_compare.__m2822sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2820sort_compare.__m2823cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2820sort_compare.__m2824cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2841sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2841sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2841sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2841sort_compare.__m2843sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2841sort_compare.__m2844cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2841sort_compare.__m2845cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2862sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2862sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2862sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2862sort_compare.__m2864sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2862sort_compare.__m2865cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2862sort_compare.__m2866cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2884sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2884sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2884sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2884sort_compare.__m2886sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2884sort_compare.__m2887cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2884sort_compare.__m2888cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2905sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2905sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2905sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2905sort_compare.__m2907sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2905sort_compare.__m2908cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2905sort_compare.__m2909cord 2022-04-01 03:28:29 root: INFO: instruction count: 6: __C2924sort_compare. 2022-04-01 03:28:29 root: INFO: instruction count: 10: __C2924sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 21: __C2924sort_compare.apply 2022-04-01 03:28:29 root: INFO: instruction count: 45: __C2924sort_compare.__m2926sort 2022-04-01 03:28:29 root: INFO: instruction count: 26: __C2924sort_compare.__m2927cord 2022-04-01 03:28:29 root: INFO: instruction count: 142: __C2924sort_compare.__m2928cord 2022-04-01 03:28:30 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:30 root: INFO: decoder cache hit 2022-04-01 03:28:30 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/parts/part-0' for reading 2022-04-01 03:28:30 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:31 root: INFO: decoder cache miss (14 hits, 23 misses, 0.378 2022-04-01 03:28:31 root: INFO: instruction count: 6: __C3062etypeDecode. 2022-04-01 03:28:31 root: INFO: instruction count: 8: __C3062etypeDecode.apply 2022-04-01 03:28:31 root: INFO: instruction count: 47: __C3062etypeDecode.__m3063DECODE_r_struct_of_o_struct_of_r_binaryANDr_int32ENDANDo_array_of_o_binaryANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_struct_of_o_binaryENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryENDANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_int32ENDANDo_float32ANDo_float64END_TO_r_tuple_of_o_locusANDo_array_of_o_stringANDo_tuple_of_o_float32ENDEND 2022-04-01 03:28:31 root: INFO: instruction count: 283: __C3062etypeDecode.__m3064read_fields_group_0 2022-04-01 03:28:31 root: INFO: instruction count: 17: __C3062etypeDecode.__m3065INPLACE_DECODE_o_struct_of_r_binaryANDr_int32END_TO_o_tuple_of_r_binaryANDr_int32END 2022-04-01 03:28:31 root: INFO: instruction count: 18: __C3062etypeDecode.__m3066read_fields_group_0 2022-04-01 03:28:31 root: INFO: instruction count: 34: __C3062etypeDecode.__m3067INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:28:31 root: INFO: instruction count: 11: __C3062etypeDecode.__m3068INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:28:31 root: INFO: instruction count: 105: __C3062etypeDecode.__m3069INPLACE_DECODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:28:31 root: INFO: instruction count: 34: __C3062etypeDecode.__m3070INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:28:31 root: INFO: instruction count: 84: __C3062etypeDecode.__m3071SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64END 2022-04-01 03:28:31 root: INFO: instruction count: 6: __C3062etypeDecode.__m3072SKIP_o_int32 2022-04-01 03:28:31 root: INFO: instruction count: 6: __C3062etypeDecode.__m3073SKIP_o_float64 2022-04-01 03:28:31 root: INFO: instruction count: 39: __C3062etypeDecode.__m3074SKIP_o_struct_of_o_binaryEND 2022-04-01 03:28:31 root: INFO: instruction count: 10: __C3062etypeDecode.__m3075SKIP_o_binary 2022-04-01 03:28:31 root: INFO: instruction count: 39: __C3062etypeDecode.__m3076SKIP_o_struct_of_o_float32END 2022-04-01 03:28:31 root: INFO: instruction count: 6: __C3062etypeDecode.__m3077SKIP_o_float32 2022-04-01 03:28:31 root: INFO: instruction count: 39: __C3062etypeDecode.__m3078SKIP_o_struct_of_o_float64END 2022-04-01 03:28:31 root: INFO: instruction count: 144: __C3062etypeDecode.__m3079SKIP_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:28:31 root: INFO: instruction count: 99: __C3062etypeDecode.__m3080SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:28:31 root: INFO: instruction count: 39: __C3062etypeDecode.__m3081SKIP_o_struct_of_o_float64END 2022-04-01 03:28:31 root: INFO: instruction count: 30: __C3062etypeDecode.__m3082INPLACE_DECODE_o_struct_of_o_float32END_TO_o_tuple_of_o_float32END 2022-04-01 03:28:31 root: INFO: instruction count: 32: __C3062etypeDecode.__m3083read_fields_group_0 2022-04-01 03:28:31 root: INFO: instruction count: 11: __C3062etypeDecode.__m3084INPLACE_DECODE_o_float32_TO_o_float32 2022-04-01 03:28:31 root: INFO: instruction count: 129: __C3062etypeDecode.__m3085SKIP_o_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:28:31 root: INFO: instruction count: 129: __C3062etypeDecode.__m3086SKIP_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:28:31 root: INFO: instruction count: 39: __C3062etypeDecode.__m3087SKIP_o_struct_of_o_int32END 2022-04-01 03:28:39 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:40 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:40 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:41 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:41 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:42 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:42 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:43 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:43 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:43 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:43 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:44 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:44 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:45 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:45 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:47 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:47 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:48 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:48 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:48 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:49 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:49 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:49 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:50 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:50 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:51 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:51 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:52 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:52 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:53 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:53 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:53 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.011ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 17: (Coalesce (InsertFields (Let __iruid_4460 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)) (InsertFields (Ref __iruid_4460) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "splice_ai" "start") (splice_ai (GetField splice_ai (GetField __uid_111 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)))) (start (Apply position () Int32 (GetField locus (Ref __iruid_4460)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},splice_ai:Struct{delta_score:Float32},start:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.301ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.053ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.107ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.268ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.036ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.484ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.057ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.047ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.076ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.215ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.032ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.749ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.070ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.061ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.093ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.295ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.043ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.093ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 7.564ms, total 3m36.1s, tagged coverage 93.6 2022-04-01 03:28:53 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 17: (Coalesce (InsertFields (Let __iruid_7266 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)) (InsertFields (Ref __iruid_7266) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "splice_ai" "start") (splice_ai (GetField splice_ai (GetField __uid_111 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)))) (start (Apply position () Int32 (GetField locus (Ref __iruid_7266)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},splice_ai:Struct{delta_score:Float32},start:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 10.288ms, total 3m36.1s, tagged coverage 68.8 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.007ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 10.445ms, total 3m36.1s, tagged coverage 67.9 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.032ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.024ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.029ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.179ms, total 3m36.1s, tagged coverage 47.0 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.004ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 17: (Coalesce (InsertFields (Let __iruid_7266 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)) (InsertFields (Ref __iruid_7266) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "splice_ai" "start") (splice_ai (GetField splice_ai (GetField __uid_111 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)))) (start (Apply position () Int32 (GetField locus (Ref __iruid_7266)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},splice_ai:Struct{delta_score:Float32},start:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.064ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.067ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.109ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.336ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.047ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.254ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.072ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.092ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.093ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.314ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.047ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.241ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.070ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.068ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.093ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.346ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.050ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 2.174ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 9.244ms, total 3m36.1s, tagged coverage 92.3 2022-04-01 03:28:53 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 17: (Coalesce (InsertFields (Let __iruid_7269 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)) (InsertFields (Ref __iruid_7269) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "splice_ai" "start") (splice_ai (GetField splice_ai (GetField __uid_111 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)))) (start (Apply position () Int32 (GetField locus (Ref __iruid_7269)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},splice_ai:Struct{delta_score:Float32},start:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 13.050ms, total 3m36.1s, tagged coverage 65.4 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.006ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 13.169ms, total 3m36.1s, tagged coverage 64.9 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.025ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 6.800ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.018ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 6.941ms, total 3m36.1s, tagged coverage 98.6 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.003ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 17: (Coalesce (InsertFields (Let __iruid_7269 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)) (InsertFields (Ref __iruid_7269) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "splice_ai" "start") (splice_ai (GetField splice_ai (GetField __uid_111 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)))) (start (Apply position () Int32 (GetField locus (Ref __iruid_7269)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},splice_ai:Struct{delta_score:Float32},start:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.047ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.073ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.072ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.216ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.047ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.349ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.060ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.041ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.068ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.206ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.044ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.370ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.049ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.042ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.068ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.205ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.029ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 1.310ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 5.683ms, total 3m36.1s, tagged coverage 93.2 2022-04-01 03:28:53 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 17: (Coalesce (InsertFields (Let __iruid_7272 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)) (InsertFields (Ref __iruid_7272) ("locus" "alleles" "rsid" "filters" "vep" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "sortedTranscriptConsequences" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "splice_ai" "start") (splice_ai (GetField splice_ai (GetField __uid_111 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)))) (start (Apply position () Int32 (GetField locus (Ref __iruid_7272)))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_111:PCStruct{splice_ai:PCStruct{delta_score:PFloat32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],rsid:String,filters:Set[String],vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},splice_ai:Struct{delta_score:Float32},start:Int32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 8.054ms, total 3m36.1s, tagged coverage 65.8 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.006ms, total 3m36.1s 2022-04-01 03:28:53 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 8.140ms, total 3m36.1s, tagged coverage 65.2 2022-04-01 03:28:53 root: INFO: encoder cache hit 2022-04-01 03:28:53 MemoryStore: INFO: Block broadcast_28 stored as values in memory (estimated size 104.0 B, free 5.6 GB) 2022-04-01 03:28:53 MemoryStore: INFO: Block broadcast_28_piece0 stored as bytes in memory (estimated size 109.0 B, free 5.6 GB) 2022-04-01 03:28:53 BlockManagerInfo: INFO: Added broadcast_28_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 109.0 B, free: 5.6 GB) 2022-04-01 03:28:53 SparkContext: INFO: Created broadcast 28 from broadcast at SparkBackend.scala:233 2022-04-01 03:28:53 root: INFO: instruction count: 6: __C3088Compiled. 2022-04-01 03:28:53 root: INFO: instruction count: 408: __C3088Compiled.apply 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3094addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 8: __C3088Compiled.__m3095addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 8: __C3088Compiled.__m3096addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 8: __C3088Compiled.__m3097addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3098addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 8: __C3088Compiled.__m3099addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3100addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3101addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 8: __C3088Compiled.__m3102addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 8: __C3088Compiled.__m3103addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3104addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3105addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3106addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3107addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3108addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 8: __C3088Compiled.__m3109addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3110addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3111addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3112addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3113addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3114addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3115addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3116addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3120addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3121position 2022-04-01 03:28:53 root: INFO: instruction count: 8: __C3088Compiled.__m3125addIRIntermediate 2022-04-01 03:28:53 root: INFO: instruction count: 14: __C3088Compiled.setPartitionIndex 2022-04-01 03:28:53 root: INFO: instruction count: 7: __C3088Compiled.addPartitionRegion 2022-04-01 03:28:53 root: INFO: instruction count: 25: __C3088Compiled.__m3129DECODE_r_struct_of_r_binaryEND_TO_r_tuple_of_r_stringEND 2022-04-01 03:28:53 root: INFO: instruction count: 11: __C3088Compiled.__m3130read_fields_group_0 2022-04-01 03:28:53 root: INFO: instruction count: 34: __C3088Compiled.__m3131INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:28:53 root: INFO: instruction count: 41: __C3088Compiled.addLiterals 2022-04-01 03:28:53 root: INFO: instruction count: 253: __C3088Compiled.applyregion88_95 2022-04-01 03:28:53 root: INFO: instruction count: 208: __C3088Compiled.applyregion176_183 2022-04-01 03:28:53 root: INFO: instruction count: 204: __C3088Compiled.applyregion273_280 2022-04-01 03:28:53 root: INFO: instruction count: 152: __C3088Compiled.applyregion0_7 2022-04-01 03:28:53 root: INFO: instruction count: 151: __C3088Compiled.applyregion184_192 2022-04-01 03:28:53 root: INFO: instruction count: 122: __C3088Compiled.applyregion32_39 2022-04-01 03:28:53 root: INFO: instruction count: 116: __C3088Compiled.applyregion80_87 2022-04-01 03:28:53 root: INFO: instruction count: 106: __C3088Compiled.applyregion217_224 2022-04-01 03:28:53 root: INFO: instruction count: 106: __C3088Compiled.applyregion120_127 2022-04-01 03:28:53 root: INFO: instruction count: 102: __C3088Compiled.applyregion201_208 2022-04-01 03:28:53 root: INFO: instruction count: 102: __C3088Compiled.applyregion104_111 2022-04-01 03:28:53 root: INFO: instruction count: 102: __C3088Compiled.applyregion16_23 2022-04-01 03:28:53 root: INFO: instruction count: 102: __C3088Compiled.applyregion225_232 2022-04-01 03:28:53 root: INFO: instruction count: 102: __C3088Compiled.applyregion128_135 2022-04-01 03:28:53 root: INFO: instruction count: 102: __C3088Compiled.applyregion56_63 2022-04-01 03:28:53 root: INFO: instruction count: 100: __C3088Compiled.applyregion249_256 2022-04-01 03:28:53 root: INFO: instruction count: 100: __C3088Compiled.applyregion193_200 2022-04-01 03:28:53 root: INFO: instruction count: 100: __C3088Compiled.applyregion152_159 2022-04-01 03:28:53 root: INFO: instruction count: 100: __C3088Compiled.applyregion96_103 2022-04-01 03:28:53 root: INFO: instruction count: 100: __C3088Compiled.applyregion40_47 2022-04-01 03:28:53 root: INFO: instruction count: 98: __C3088Compiled.applyregion8_15 2022-04-01 03:28:53 root: INFO: instruction count: 98: __C3088Compiled.applyregion24_31 2022-04-01 03:28:53 root: INFO: instruction count: 96: __C3088Compiled.applyregion233_240 2022-04-01 03:28:53 root: INFO: instruction count: 96: __C3088Compiled.applyregion209_216 2022-04-01 03:28:53 root: INFO: instruction count: 96: __C3088Compiled.applyregion136_143 2022-04-01 03:28:53 root: INFO: instruction count: 96: __C3088Compiled.applyregion112_119 2022-04-01 03:28:53 root: INFO: instruction count: 92: __C3088Compiled.applyregion281_287 2022-04-01 03:28:53 root: INFO: instruction count: 82: __C3088Compiled.applyregion241_248 2022-04-01 03:28:53 root: INFO: instruction count: 82: __C3088Compiled.applyregion144_151 2022-04-01 03:28:53 root: INFO: instruction count: 80: __C3088Compiled.applyregion257_264 2022-04-01 03:28:53 root: INFO: instruction count: 80: __C3088Compiled.applyregion160_167 2022-04-01 03:28:53 root: INFO: instruction count: 80: __C3088Compiled.applyregion72_79 2022-04-01 03:28:53 root: INFO: instruction count: 6: __C3133applySpills. 2022-04-01 03:28:54 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:28:55 root: INFO: decoder cache hit 2022-04-01 03:28:55 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/parts/part-0' for reading 2022-04-01 03:28:55 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:28:55 root: INFO: decoder cache miss (15 hits, 24 misses, 0.385 2022-04-01 03:28:56 root: INFO: instruction count: 6: __C3176etypeDecode. 2022-04-01 03:28:56 root: INFO: instruction count: 8: __C3176etypeDecode.apply 2022-04-01 03:28:56 root: INFO: instruction count: 47: __C3176etypeDecode.__m3177DECODE_r_struct_of_o_struct_of_r_binaryANDr_int32ENDANDo_array_of_o_binaryANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_struct_of_o_binaryENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryENDANDo_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ENDANDo_struct_of_o_float32ENDANDo_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_struct_of_o_int32ENDANDo_float32ANDo_float64END_TO_r_tuple_of_o_locusANDo_array_of_o_stringANDo_tuple_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDEND 2022-04-01 03:28:56 root: INFO: instruction count: 283: __C3176etypeDecode.__m3178read_fields_group_0 2022-04-01 03:28:56 root: INFO: instruction count: 17: __C3176etypeDecode.__m3179INPLACE_DECODE_o_struct_of_r_binaryANDr_int32END_TO_o_tuple_of_r_binaryANDr_int32END 2022-04-01 03:28:56 root: INFO: instruction count: 18: __C3176etypeDecode.__m3180read_fields_group_0 2022-04-01 03:28:56 root: INFO: instruction count: 34: __C3176etypeDecode.__m3181INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:28:56 root: INFO: instruction count: 11: __C3176etypeDecode.__m3182INPLACE_DECODE_r_int32_TO_r_int32 2022-04-01 03:28:56 root: INFO: instruction count: 105: __C3176etypeDecode.__m3183INPLACE_DECODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:28:56 root: INFO: instruction count: 34: __C3176etypeDecode.__m3184INPLACE_DECODE_o_binary_TO_o_binary 2022-04-01 03:28:56 root: INFO: instruction count: 84: __C3176etypeDecode.__m3185SKIP_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64END 2022-04-01 03:28:56 root: INFO: instruction count: 6: __C3176etypeDecode.__m3186SKIP_o_int32 2022-04-01 03:28:56 root: INFO: instruction count: 6: __C3176etypeDecode.__m3187SKIP_o_float64 2022-04-01 03:28:56 root: INFO: instruction count: 39: __C3176etypeDecode.__m3188SKIP_o_struct_of_o_binaryEND 2022-04-01 03:28:56 root: INFO: instruction count: 10: __C3176etypeDecode.__m3189SKIP_o_binary 2022-04-01 03:28:56 root: INFO: instruction count: 39: __C3176etypeDecode.__m3190SKIP_o_struct_of_o_float32END 2022-04-01 03:28:56 root: INFO: instruction count: 6: __C3176etypeDecode.__m3191SKIP_o_float32 2022-04-01 03:28:56 root: INFO: instruction count: 39: __C3176etypeDecode.__m3192SKIP_o_struct_of_o_float64END 2022-04-01 03:28:56 root: INFO: instruction count: 144: __C3176etypeDecode.__m3193SKIP_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:28:56 root: INFO: instruction count: 30: __C3176etypeDecode.__m3194INPLACE_DECODE_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_tuple_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:28:56 root: INFO: instruction count: 144: __C3176etypeDecode.__m3195read_fields_group_0 2022-04-01 03:28:56 root: INFO: instruction count: 11: __C3176etypeDecode.__m3196INPLACE_DECODE_o_int32_TO_o_int32 2022-04-01 03:28:56 root: INFO: instruction count: 11: __C3176etypeDecode.__m3197INPLACE_DECODE_o_float64_TO_o_float64 2022-04-01 03:28:56 root: INFO: instruction count: 39: __C3176etypeDecode.__m3198SKIP_o_struct_of_o_float64END 2022-04-01 03:28:56 root: INFO: instruction count: 39: __C3176etypeDecode.__m3199SKIP_o_struct_of_o_float32END 2022-04-01 03:28:56 root: INFO: instruction count: 129: __C3176etypeDecode.__m3200SKIP_o_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:28:56 root: INFO: instruction count: 129: __C3176etypeDecode.__m3201SKIP_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:28:56 root: INFO: instruction count: 39: __C3176etypeDecode.__m3202SKIP_o_struct_of_o_int32END 2022-04-01 03:29:04 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:05 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:05 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:06 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:06 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:07 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:07 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:08 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:08 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:08 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:08 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:09 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:09 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:10 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:10 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:11 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:12 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:12 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:13 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:14 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:14 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:15 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:15 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:16 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:16 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:16 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:16 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:17 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:17 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:18 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:18 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:19 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/all_reference_data/combined_reference_data_grch38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:19 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/rows/metadata.json.gz' for reading 2022-04-01 03:29:19 S3NativeFileSystem: INFO: Opening 's3://seqr-dp-data--prod/seqr-reference-data/GRCh38/CLINVAR/clinvar.GRCh38.ht/globals/metadata.json.gz' for reading 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.032ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 206: (Coalesce (InsertFields (Let __iruid_4461 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)) (Let __iruid_4462 (GetField locus (Ref __iruid_4461)) (Let __iruid_4463 (GetField alleles (Ref __iruid_4461)) (Let __iruid_4464 (GetField locus (Ref __iruid_4461)) (Let __iruid_4465 (GetField locus (Ref __iruid_4461)) (Let __iruid_4466 (GetField locus (Ref __iruid_4461)) (InsertFields (SelectFields (locus alleles aIndex AC AF alt AN cadd clinvar codingGeneIds contig dbnsfp docId domains eigen end exac filters g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref rsid samples_ab samples_gq samples_no_call samples_num_alt sortedTranscriptConsequences splice_ai start vep) (Ref __iruid_4461)) ("locus" "alleles" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "filters" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "rsid" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "sortedTranscriptConsequences" "splice_ai" "start" "topmed" "transcriptConsequenceTerms" "transcriptIds" "utrVariantAnnotation" "variantId" "vep" "xpos" "xstart" "xstop") (topmed (GetField topmed (GetField __uid_112 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)))) (transcriptConsequenceTerms (ToSet (StreamFlatMap __iruid_4467 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_4461))) (ToStream False (GetField consequence_terms (Ref __iruid_4467)))))) (transcriptIds (ToSet (StreamMap __iruid_4468 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_4461))) (GetField transcript_id (Ref __iruid_4468))))) (utrVariantAnnotation (ToArray (StreamMap __iruid_4469 (StreamFilter __iruid_4470 (ToStream False (GetField transcript_consequences (GetField vep (Ref __iruid_4461)))) (Let __iruid_4471 (Str "5_prime_UT...") (StreamFold __iruid_4472 __iruid_4473 (ToStream False (GetField consequence_terms (Ref __iruid_4470))) (False) (ApplySpecial lor () Boolean (Ref __iruid_4472) (ApplyComparisonOp EQWithNA (Ref __iruid_4473) (Ref __iruid_4471)))))) (MakeStruct (existing_inframe_oorfs (GetField existing_inframe_oorfs (Ref __iruid_4469))) (existing_outofframe_oorfs (GetField existing_outofframe_oorfs (Ref __iruid_4469))) (existing_uorfs (GetField existing_uorfs (Ref __iruid_4469))) (five_prime_utr_variant_consequence (GetField five_prime_utr_variant_consequence (Ref __iruid_4469))) (five_prime_utr_variant_annotation (GetField five_prime_utr_variant_annotation (Ref __iruid_4469))))))) (variantId (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_4462)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_4462)))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_4463) (I32 0) (Str " File \"/h..."))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_4463) (I32 1) (Str " File \"/h...")))) (xpos (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_4474 (Apply replace () String (Apply contig () String (Ref __iruid_4464)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_4474) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_4474) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __iruid_4474) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_4474))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_4464))))) (xstart (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_4475 (Apply replace () String (Apply contig () String (Ref __iruid_4465)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_4475) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_4475) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __iruid_4475) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_4475))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_4465))))) (xstop (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_4476 (Apply replace () String (Apply contig () String (Ref __iruid_4466)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_4476) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_4476) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __iruid_4476) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_4476))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_4466)))) (Cast Int64 (Apply length () Int32 (ApplyIR indexArray () String (GetField alleles (Ref __iruid_4461)) (I32 0) (Str " File \"/h..."))))) (I64 1)))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},filters:Set[String],g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,rsid:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],splice_ai:Struct{delta_score:Float32},start:Int32,topmed:Struct{AC:Int32,AF:Float64,AN:Int32,Hom:Int32,Het:Int32},transcriptConsequenceTerms:Set[String],transcriptIds:Set[String],utrVariantAnnotation:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String}],variantId:String,vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},xpos:Int64,xstart:Int64,xstop:Int64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 1.510ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.474ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 2.352ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 3.102ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.500ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 9.123ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.742ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.454ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 2.215ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 2.999ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.509ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 8.445ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.766ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.467ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 2.192ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 3.145ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.495ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 8.098ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 48.523ms, total 4m2.8s, tagged coverage 98.1 2022-04-01 03:29:20 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 206: (Coalesce (InsertFields (Let __iruid_7480 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)) (Let __iruid_7481 (GetField locus (Ref __iruid_7480)) (Let __iruid_7482 (GetField alleles (Ref __iruid_7480)) (Let __iruid_7483 (GetField locus (Ref __iruid_7480)) (Let __iruid_7484 (GetField locus (Ref __iruid_7480)) (Let __iruid_7485 (GetField locus (Ref __iruid_7480)) (InsertFields (SelectFields (locus alleles aIndex AC AF alt AN cadd clinvar codingGeneIds contig dbnsfp docId domains eigen end exac filters g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref rsid samples_ab samples_gq samples_no_call samples_num_alt sortedTranscriptConsequences splice_ai start vep) (Ref __iruid_7480)) ("locus" "alleles" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "filters" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "rsid" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "sortedTranscriptConsequences" "splice_ai" "start" "topmed" "transcriptConsequenceTerms" "transcriptIds" "utrVariantAnnotation" "variantId" "vep" "xpos" "xstart" "xstop") (topmed (GetField topmed (GetField __uid_112 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)))) (transcriptConsequenceTerms (ToSet (StreamFlatMap __iruid_7486 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_7480))) (ToStream False (GetField consequence_terms (Ref __iruid_7486)))))) (transcriptIds (ToSet (StreamMap __iruid_7487 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_7480))) (GetField transcript_id (Ref __iruid_7487))))) (utrVariantAnnotation (ToArray (StreamMap __iruid_7488 (StreamFilter __iruid_7489 (ToStream False (GetField transcript_consequences (GetField vep (Ref __iruid_7480)))) (Let __iruid_7490 (Str "5_prime_UT...") (StreamFold __iruid_7491 __iruid_7492 (ToStream False (GetField consequence_terms (Ref __iruid_7489))) (False) (ApplySpecial lor () Boolean (Ref __iruid_7491) (ApplyComparisonOp EQWithNA (Ref __iruid_7492) (Ref __iruid_7490)))))) (MakeStruct (existing_inframe_oorfs (GetField existing_inframe_oorfs (Ref __iruid_7488))) (existing_outofframe_oorfs (GetField existing_outofframe_oorfs (Ref __iruid_7488))) (existing_uorfs (GetField existing_uorfs (Ref __iruid_7488))) (five_prime_utr_variant_consequence (GetField five_prime_utr_variant_consequence (Ref __iruid_7488))) (five_prime_utr_variant_annotation (GetField five_prime_utr_variant_annotation (Ref __iruid_7488))))))) (variantId (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_7481)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_7481)))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_7482) (I32 0) (Str " File \"/h..."))) (Str "-")) (ApplyIR indexArray () String (Ref __iruid_7482) (I32 1) (Str " File \"/h...")))) (xpos (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_7493 (Apply replace () String (Apply contig () String (Ref __iruid_7483)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_7493) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_7493) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __iruid_7493) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_7493))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_7483))))) (xstart (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_7494 (Apply replace () String (Apply contig () String (Ref __iruid_7484)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_7494) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_7494) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __iruid_7494) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_7494))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_7484))))) (xstop (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_7495 (Apply replace () String (Apply contig () String (Ref __iruid_7485)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_7495) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_7495) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (ApplyIR index () String (Ref __iruid_7495) (I32 0)) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_7495))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_7485)))) (Cast Int64 (Apply length () Int32 (ApplyIR indexArray () String (GetField alleles (Ref __iruid_7480)) (I32 0) (Str " File \"/h..."))))) (I64 1)))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},filters:Set[String],g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,rsid:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],splice_ai:Struct{delta_score:Float32},start:Int32,topmed:Struct{AC:Int32,AF:Float64,AN:Int32,Hom:Int32,Het:Int32},transcriptConsequenceTerms:Set[String],transcriptIds:Set[String],utrVariantAnnotation:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String}],variantId:String,vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},xpos:Int64,xstart:Int64,xstop:Int64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 54.582ms, total 4m2.8s, tagged coverage 87.2 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.019ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 54.770ms, total 4m2.8s, tagged coverage 87.0 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.046ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.493ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.120ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.788ms, total 4m2.8s, tagged coverage 83.6 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.024ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 362: (Coalesce (InsertFields (Let __iruid_7480 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)) (Let __iruid_7481 (GetField locus (Ref __iruid_7480)) (Let __iruid_7482 (GetField alleles (Ref __iruid_7480)) (Let __iruid_7483 (GetField locus (Ref __iruid_7480)) (Let __iruid_7484 (GetField locus (Ref __iruid_7480)) (Let __iruid_7485 (GetField locus (Ref __iruid_7480)) (InsertFields (SelectFields (locus alleles aIndex AC AF alt AN cadd clinvar codingGeneIds contig dbnsfp docId domains eigen end exac filters g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref rsid samples_ab samples_gq samples_no_call samples_num_alt sortedTranscriptConsequences splice_ai start vep) (Ref __iruid_7480)) ("locus" "alleles" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "filters" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "rsid" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "sortedTranscriptConsequences" "splice_ai" "start" "topmed" "transcriptConsequenceTerms" "transcriptIds" "utrVariantAnnotation" "variantId" "vep" "xpos" "xstart" "xstop") (topmed (GetField topmed (GetField __uid_112 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)))) (transcriptConsequenceTerms (ToSet (StreamFlatMap __iruid_7486 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_7480))) (ToStream False (GetField consequence_terms (Ref __iruid_7486)))))) (transcriptIds (ToSet (StreamMap __iruid_7487 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_7480))) (GetField transcript_id (Ref __iruid_7487))))) (utrVariantAnnotation (ToArray (StreamMap __iruid_7488 (StreamFilter __iruid_7489 (ToStream False (GetField transcript_consequences (GetField vep (Ref __iruid_7480)))) (Let __iruid_7490 (Str "5_prime_UT...") (StreamFold __iruid_7491 __iruid_7492 (ToStream False (GetField consequence_terms (Ref __iruid_7489))) (False) (ApplySpecial lor () Boolean (Ref __iruid_7491) (ApplyComparisonOp EQWithNA (Ref __iruid_7492) (Ref __iruid_7490)))))) (MakeStruct (existing_inframe_oorfs (GetField existing_inframe_oorfs (Ref __iruid_7488))) (existing_outofframe_oorfs (GetField existing_outofframe_oorfs (Ref __iruid_7488))) (existing_uorfs (GetField existing_uorfs (Ref __iruid_7488))) (five_prime_utr_variant_consequence (GetField five_prime_utr_variant_consequence (Ref __iruid_7488))) (five_prime_utr_variant_annotation (GetField five_prime_utr_variant_annotation (Ref __iruid_7488))))))) (variantId (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_7481)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_7481)))) (Str "-")) (Let __iruid_7529 (Ref __iruid_7482) (Let __iruid_7530 (I32 0) (Let __iruid_7531 (Str " File \"/h...") (ArrayRef (Ref __iruid_7529) (If (ApplyComparisonOp LT (Ref __iruid_7530) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_7529)) (Ref __iruid_7530)) (Ref __iruid_7530)) (Ref __iruid_7531)))))) (Str "-")) (Let __iruid_7532 (Ref __iruid_7482) (Let __iruid_7533 (I32 1) (Let __iruid_7534 (Str " File \"/h...") (ArrayRef (Ref __iruid_7532) (If (ApplyComparisonOp LT (Ref __iruid_7533) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_7532)) (Ref __iruid_7533)) (Ref __iruid_7533)) (Ref __iruid_7534))))))) (xpos (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_7493 (Apply replace () String (Apply contig () String (Ref __iruid_7483)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_7493) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_7493) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (Let __iruid_7517 (Ref __iruid_7493) (Let __iruid_7518 (I32 0) (Let __iruid_7519 (Apply length () Int32 (Ref __iruid_7517)) (Let __iruid_7520 (If (ApplySpecial lor () Boolean (ApplyComparisonOp LT (Ref __iruid_7518) (ApplyUnaryPrimOp Negate (Ref __iruid_7519))) (ApplyComparisonOp GTEQ (Ref __iruid_7518) (Ref __iruid_7519))) (Die Int32 (Apply concat () String (Str "string ind...") (Apply concat () String (Apply str () String (Ref __iruid_7518)) (Apply concat () String (Str " / ") (Apply str () String (Ref __iruid_7519)))))) (If (ApplyComparisonOp LT (Ref __iruid_7518) (I32 0)) (ApplyBinaryPrimOp Add (Ref __iruid_7518) (Ref __iruid_7519)) (Ref __iruid_7518))) (Apply substring () String (Ref __iruid_7517) (Ref __iruid_7520) (ApplyBinaryPrimOp Add (Ref __iruid_7520) (I32 1))))))) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_7493))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_7483))))) (xstart (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_7494 (Apply replace () String (Apply contig () String (Ref __iruid_7484)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_7494) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_7494) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (Let __iruid_7521 (Ref __iruid_7494) (Let __iruid_7522 (I32 0) (Let __iruid_7523 (Apply length () Int32 (Ref __iruid_7521)) (Let __iruid_7524 (If (ApplySpecial lor () Boolean (ApplyComparisonOp LT (Ref __iruid_7522) (ApplyUnaryPrimOp Negate (Ref __iruid_7523))) (ApplyComparisonOp GTEQ (Ref __iruid_7522) (Ref __iruid_7523))) (Die Int32 (Apply concat () String (Str "string ind...") (Apply concat () String (Apply str () String (Ref __iruid_7522)) (Apply concat () String (Str " / ") (Apply str () String (Ref __iruid_7523)))))) (If (ApplyComparisonOp LT (Ref __iruid_7522) (I32 0)) (ApplyBinaryPrimOp Add (Ref __iruid_7522) (Ref __iruid_7523)) (Ref __iruid_7522))) (Apply substring () String (Ref __iruid_7521) (Ref __iruid_7524) (ApplyBinaryPrimOp Add (Ref __iruid_7524) (I32 1))))))) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_7494))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_7484))))) (xstop (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_7495 (Apply replace () String (Apply contig () String (Ref __iruid_7485)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_7495) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_7495) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (Let __iruid_7525 (Ref __iruid_7495) (Let __iruid_7526 (I32 0) (Let __iruid_7527 (Apply length () Int32 (Ref __iruid_7525)) (Let __iruid_7528 (If (ApplySpecial lor () Boolean (ApplyComparisonOp LT (Ref __iruid_7526) (ApplyUnaryPrimOp Negate (Ref __iruid_7527))) (ApplyComparisonOp GTEQ (Ref __iruid_7526) (Ref __iruid_7527))) (Die Int32 (Apply concat () String (Str "string ind...") (Apply concat () String (Apply str () String (Ref __iruid_7526)) (Apply concat () String (Str " / ") (Apply str () String (Ref __iruid_7527)))))) (If (ApplyComparisonOp LT (Ref __iruid_7526) (I32 0)) (ApplyBinaryPrimOp Add (Ref __iruid_7526) (Ref __iruid_7527)) (Ref __iruid_7526))) (Apply substring () String (Ref __iruid_7525) (Ref __iruid_7528) (ApplyBinaryPrimOp Add (Ref __iruid_7528) (I32 1))))))) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_7495))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_7485)))) (Cast Int64 (Apply length () Int32 (Let __iruid_7535 (GetField alleles (Ref __iruid_7480)) (Let __iruid_7536 (I32 0) (Let __iruid_7537 (Str " File \"/h...") (ArrayRef (Ref __iruid_7535) (If (ApplyComparisonOp LT (Ref __iruid_7536) (I32 0)) (ApplyBinaryPrimOp Add (ArrayLen (Ref __iruid_7535)) (Ref __iruid_7536)) (Ref __iruid_7536)) (Ref __iruid_7537)))))))) (I64 1)))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},filters:Set[String],g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,rsid:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],splice_ai:Struct{delta_score:Float32},start:Int32,topmed:Struct{AC:Int32,AF:Float64,AN:Int32,Hom:Int32,Het:Int32},transcriptConsequenceTerms:Set[String],transcriptIds:Set[String],utrVariantAnnotation:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String}],variantId:String,vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},xpos:Int64,xstart:Int64,xstop:Int64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.476ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.710ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 1.755ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 5.824ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.675ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 8.058ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants -- InlineApplyIR -- Verify : 0.091ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants -- InlineApplyIR -- LoweringTransformation : 0.009ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants -- InlineApplyIR -- Verify : 0.004ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants -- InlineApplyIR : 0.179ms, total 4m2.8s, tagged coverage 58.5 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants -- LowerArrayAggsToRunAggs -- Verify : 0.003ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants -- LowerArrayAggsToRunAggs -- LoweringTransformation : 0.190ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants -- LowerArrayAggsToRunAggs -- Verify : 0.005ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants -- LowerArrayAggsToRunAggs : 0.267ms, total 4m2.8s, tagged coverage 73.7 2022-04-01 03:29:20 root: INFO: instruction count: 6: __C3203Compiled. 2022-04-01 03:29:20 root: INFO: instruction count: 63: __C3203Compiled.apply 2022-04-01 03:29:20 root: INFO: instruction count: 61: __C3203Compiled.__m3206str 2022-04-01 03:29:20 root: INFO: instruction count: 15: __C3203Compiled.__m3209setup_null 2022-04-01 03:29:20 root: INFO: instruction count: 8: __C3203Compiled.__m3212addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 14: __C3203Compiled.setPartitionIndex 2022-04-01 03:29:20 root: INFO: instruction count: 7: __C3203Compiled.addPartitionRegion 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 10.609ms, total 4m2.8s, tagged coverage 2.8 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.680ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 2.479ms, total 4m2.8s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 4.435ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.855ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 7.367ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.886ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.533ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 1.787ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 3.959ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.815ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 6.846ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 59.655ms, total 4m2.9s, tagged coverage 81.2 2022-04-01 03:29:20 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 284: (Coalesce (InsertFields (Let __iruid_7598 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)) (Let __iruid_7599 (GetField locus (Ref __iruid_7598)) (Let __iruid_7600 (GetField alleles (Ref __iruid_7598)) (Let __iruid_7601 (GetField locus (Ref __iruid_7598)) (Let __iruid_7602 (GetField locus (Ref __iruid_7598)) (Let __iruid_7603 (GetField locus (Ref __iruid_7598)) (InsertFields (SelectFields (locus alleles aIndex AC AF alt AN cadd clinvar codingGeneIds contig dbnsfp docId domains eigen end exac filters g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref rsid samples_ab samples_gq samples_no_call samples_num_alt sortedTranscriptConsequences splice_ai start vep) (Ref __iruid_7598)) ("locus" "alleles" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "filters" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "rsid" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "sortedTranscriptConsequences" "splice_ai" "start" "topmed" "transcriptConsequenceTerms" "transcriptIds" "utrVariantAnnotation" "variantId" "vep" "xpos" "xstart" "xstop") (topmed (GetField topmed (GetField __uid_112 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)))) (transcriptConsequenceTerms (ToSet (StreamFlatMap __iruid_7604 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_7598))) (ToStream False (GetField consequence_terms (Ref __iruid_7604)))))) (transcriptIds (ToSet (StreamMap __iruid_7605 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_7598))) (GetField transcript_id (Ref __iruid_7605))))) (utrVariantAnnotation (ToArray (StreamMap __iruid_7606 (StreamFilter __iruid_7607 (ToStream False (GetField transcript_consequences (GetField vep (Ref __iruid_7598)))) (Let __iruid_7608 (Str "5_prime_UT...") (StreamFold __iruid_7609 __iruid_7610 (ToStream False (GetField consequence_terms (Ref __iruid_7607))) (False) (ApplySpecial lor () Boolean (Ref __iruid_7609) (ApplyComparisonOp EQWithNA (Ref __iruid_7610) (Ref __iruid_7608)))))) (MakeStruct (existing_inframe_oorfs (GetField existing_inframe_oorfs (Ref __iruid_7606))) (existing_outofframe_oorfs (GetField existing_outofframe_oorfs (Ref __iruid_7606))) (existing_uorfs (GetField existing_uorfs (Ref __iruid_7606))) (five_prime_utr_variant_consequence (GetField five_prime_utr_variant_consequence (Ref __iruid_7606))) (five_prime_utr_variant_annotation (GetField five_prime_utr_variant_annotation (Ref __iruid_7606))))))) (variantId (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_7599)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_7599)))) (Str "-")) (ArrayRef (Ref __iruid_7600) (I32 0) (Str " File \"/h..."))) (Str "-")) (ArrayRef (Ref __iruid_7600) (I32 1) (Str " File \"/h...")))) (xpos (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_7611 (Apply replace () String (Apply contig () String (Ref __iruid_7601)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_7611) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_7611) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (Let __iruid_7612 (Apply length () Int32 (Ref __iruid_7611)) (Let __iruid_7613 (If (ApplySpecial lor () Boolean (ApplyComparisonOp LT (I32 0) (ApplyUnaryPrimOp Negate (Ref __iruid_7612))) (ApplyComparisonOp GTEQ (I32 0) (Ref __iruid_7612))) (Die Int32 (Apply concat () String (Str "string ind...") (Apply concat () String (Str "0") (Apply concat () String (Str " / ") (Apply str () String (Ref __iruid_7612)))))) (I32 0)) (Apply substring () String (Ref __iruid_7611) (Ref __iruid_7613) (ApplyBinaryPrimOp Add (Ref __iruid_7613) (I32 1))))) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_7611))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_7601))))) (xstart (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_7614 (Apply replace () String (Apply contig () String (Ref __iruid_7602)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_7614) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_7614) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (Let __iruid_7615 (Apply length () Int32 (Ref __iruid_7614)) (Let __iruid_7616 (If (ApplySpecial lor () Boolean (ApplyComparisonOp LT (I32 0) (ApplyUnaryPrimOp Negate (Ref __iruid_7615))) (ApplyComparisonOp GTEQ (I32 0) (Ref __iruid_7615))) (Die Int32 (Apply concat () String (Str "string ind...") (Apply concat () String (Str "0") (Apply concat () String (Str " / ") (Apply str () String (Ref __iruid_7615)))))) (I32 0)) (Apply substring () String (Ref __iruid_7614) (Ref __iruid_7616) (ApplyBinaryPrimOp Add (Ref __iruid_7616) (I32 1))))) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_7614))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_7602))))) (xstop (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_7617 (Apply replace () String (Apply contig () String (Ref __iruid_7603)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_7617) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_7617) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (Let __iruid_7618 (Apply length () Int32 (Ref __iruid_7617)) (Let __iruid_7619 (If (ApplySpecial lor () Boolean (ApplyComparisonOp LT (I32 0) (ApplyUnaryPrimOp Negate (Ref __iruid_7618))) (ApplyComparisonOp GTEQ (I32 0) (Ref __iruid_7618))) (Die Int32 (Apply concat () String (Str "string ind...") (Apply concat () String (Str "0") (Apply concat () String (Str " / ") (Apply str () String (Ref __iruid_7618)))))) (I32 0)) (Apply substring () String (Ref __iruid_7617) (Ref __iruid_7619) (ApplyBinaryPrimOp Add (Ref __iruid_7619) (I32 1))))) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_7617))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_7603)))) (Cast Int64 (Apply length () Int32 (ArrayRef (GetField alleles (Ref __iruid_7598)) (I32 0) (Str " File \"/h..."))))) (I64 1)))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},filters:Set[String],g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,rsid:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],splice_ai:Struct{delta_score:Float32},start:Int32,topmed:Struct{AC:Int32,AF:Float64,AN:Int32,Hom:Int32,Het:Int32},transcriptConsequenceTerms:Set[String],transcriptIds:Set[String],utrVariantAnnotation:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String}],variantId:String,vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},xpos:Int64,xstart:Int64,xstop:Int64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 66.839ms, total 4m2.9s, tagged coverage 72.5 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.024ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 67.007ms, total 4m2.9s, tagged coverage 72.4 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.053ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 32.099ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.065ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 32.374ms, total 4m2.9s, tagged coverage 99.5 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.019ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 284: (Coalesce (InsertFields (Let __iruid_7598 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)) (Let __iruid_7599 (GetField locus (Ref __iruid_7598)) (Let __iruid_7600 (GetField alleles (Ref __iruid_7598)) (Let __iruid_7601 (GetField locus (Ref __iruid_7598)) (Let __iruid_7602 (GetField locus (Ref __iruid_7598)) (Let __iruid_7603 (GetField locus (Ref __iruid_7598)) (InsertFields (SelectFields (locus alleles aIndex AC AF alt AN cadd clinvar codingGeneIds contig dbnsfp docId domains eigen end exac filters g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref rsid samples_ab samples_gq samples_no_call samples_num_alt sortedTranscriptConsequences splice_ai start vep) (Ref __iruid_7598)) ("locus" "alleles" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "filters" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "rsid" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "sortedTranscriptConsequences" "splice_ai" "start" "topmed" "transcriptConsequenceTerms" "transcriptIds" "utrVariantAnnotation" "variantId" "vep" "xpos" "xstart" "xstop") (topmed (GetField topmed (GetField __uid_112 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)))) (transcriptConsequenceTerms (ToSet (StreamFlatMap __iruid_7604 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_7598))) (ToStream False (GetField consequence_terms (Ref __iruid_7604)))))) (transcriptIds (ToSet (StreamMap __iruid_7605 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_7598))) (GetField transcript_id (Ref __iruid_7605))))) (utrVariantAnnotation (ToArray (StreamMap __iruid_7606 (StreamFilter __iruid_7607 (ToStream False (GetField transcript_consequences (GetField vep (Ref __iruid_7598)))) (Let __iruid_7608 (Str "5_prime_UT...") (StreamFold __iruid_7609 __iruid_7610 (ToStream False (GetField consequence_terms (Ref __iruid_7607))) (False) (ApplySpecial lor () Boolean (Ref __iruid_7609) (ApplyComparisonOp EQWithNA (Ref __iruid_7610) (Ref __iruid_7608)))))) (MakeStruct (existing_inframe_oorfs (GetField existing_inframe_oorfs (Ref __iruid_7606))) (existing_outofframe_oorfs (GetField existing_outofframe_oorfs (Ref __iruid_7606))) (existing_uorfs (GetField existing_uorfs (Ref __iruid_7606))) (five_prime_utr_variant_consequence (GetField five_prime_utr_variant_consequence (Ref __iruid_7606))) (five_prime_utr_variant_annotation (GetField five_prime_utr_variant_annotation (Ref __iruid_7606))))))) (variantId (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_7599)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_7599)))) (Str "-")) (ArrayRef (Ref __iruid_7600) (I32 0) (Str " File \"/h..."))) (Str "-")) (ArrayRef (Ref __iruid_7600) (I32 1) (Str " File \"/h...")))) (xpos (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_7611 (Apply replace () String (Apply contig () String (Ref __iruid_7601)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_7611) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_7611) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (Let __iruid_7612 (Apply length () Int32 (Ref __iruid_7611)) (Let __iruid_7613 (If (ApplySpecial lor () Boolean (ApplyComparisonOp LT (I32 0) (ApplyUnaryPrimOp Negate (Ref __iruid_7612))) (ApplyComparisonOp GTEQ (I32 0) (Ref __iruid_7612))) (Die Int32 (Apply concat () String (Str "string ind...") (Apply concat () String (Str "0") (Apply concat () String (Str " / ") (Apply str () String (Ref __iruid_7612)))))) (I32 0)) (Apply substring () String (Ref __iruid_7611) (Ref __iruid_7613) (ApplyBinaryPrimOp Add (Ref __iruid_7613) (I32 1))))) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_7611))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_7601))))) (xstart (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_7614 (Apply replace () String (Apply contig () String (Ref __iruid_7602)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_7614) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_7614) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (Let __iruid_7615 (Apply length () Int32 (Ref __iruid_7614)) (Let __iruid_7616 (If (ApplySpecial lor () Boolean (ApplyComparisonOp LT (I32 0) (ApplyUnaryPrimOp Negate (Ref __iruid_7615))) (ApplyComparisonOp GTEQ (I32 0) (Ref __iruid_7615))) (Die Int32 (Apply concat () String (Str "string ind...") (Apply concat () String (Str "0") (Apply concat () String (Str " / ") (Apply str () String (Ref __iruid_7615)))))) (I32 0)) (Apply substring () String (Ref __iruid_7614) (Ref __iruid_7616) (ApplyBinaryPrimOp Add (Ref __iruid_7616) (I32 1))))) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_7614))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_7602))))) (xstop (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_7617 (Apply replace () String (Apply contig () String (Ref __iruid_7603)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_7617) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_7617) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (Let __iruid_7618 (Apply length () Int32 (Ref __iruid_7617)) (Let __iruid_7619 (If (ApplySpecial lor () Boolean (ApplyComparisonOp LT (I32 0) (ApplyUnaryPrimOp Negate (Ref __iruid_7618))) (ApplyComparisonOp GTEQ (I32 0) (Ref __iruid_7618))) (Die Int32 (Apply concat () String (Str "string ind...") (Apply concat () String (Str "0") (Apply concat () String (Str " / ") (Apply str () String (Ref __iruid_7618)))))) (I32 0)) (Apply substring () String (Ref __iruid_7617) (Ref __iruid_7619) (ApplyBinaryPrimOp Add (Ref __iruid_7619) (I32 1))))) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_7617))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_7603)))) (Cast Int64 (Apply length () Int32 (ArrayRef (GetField alleles (Ref __iruid_7598)) (I32 0) (Str " File \"/h..."))))) (I64 1)))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},filters:Set[String],g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,rsid:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],splice_ai:Struct{delta_score:Float32},start:Int32,topmed:Struct{AC:Int32,AF:Float64,AN:Int32,Hom:Int32,Het:Int32},transcriptConsequenceTerms:Set[String],transcriptIds:Set[String],utrVariantAnnotation:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String}],variantId:String,vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},xpos:Int64,xstart:Int64,xstop:Int64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.384ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.588ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 1.917ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 4.153ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.912ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 7.542ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.956ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.611ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 1.918ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 4.981ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.915ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 7.417ms, total 4m2.9s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.961ms, total 4m3.0s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.579ms, total 4m3.0s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 1.903ms, total 4m3.0s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 3.899ms, total 4m3.0s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.918ms, total 4m3.0s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 7.548ms, total 4m3.0s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 48.969ms, total 4m3.0s, tagged coverage 98.2 2022-04-01 03:29:20 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 284: (Coalesce (InsertFields (Let __iruid_7664 (SelectFields (locus alleles rsid filters vep aIndex AC AF alt AN cadd clinvar sortedTranscriptConsequences codingGeneIds contig dbnsfp docId domains eigen end exac g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref samples_ab samples_gq samples_no_call samples_num_alt splice_ai start) (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)) (Let __iruid_7665 (GetField locus (Ref __iruid_7664)) (Let __iruid_7666 (GetField alleles (Ref __iruid_7664)) (Let __iruid_7667 (GetField locus (Ref __iruid_7664)) (Let __iruid_7668 (GetField locus (Ref __iruid_7664)) (Let __iruid_7669 (GetField locus (Ref __iruid_7664)) (InsertFields (SelectFields (locus alleles aIndex AC AF alt AN cadd clinvar codingGeneIds contig dbnsfp docId domains eigen end exac filters g1k geneIds geno2mp genotypes gnomad_exome_coverage gnomad_exomes gnomad_genome_coverage gnomad_genomes mainTranscript mpc originalAltAlleles pos primate_ai ref rsid samples_ab samples_gq samples_no_call samples_num_alt sortedTranscriptConsequences splice_ai start vep) (Ref __iruid_7664)) ("locus" "alleles" "aIndex" "AC" "AF" "alt" "AN" "cadd" "clinvar" "codingGeneIds" "contig" "dbnsfp" "docId" "domains" "eigen" "end" "exac" "filters" "g1k" "geneIds" "geno2mp" "genotypes" "gnomad_exome_coverage" "gnomad_exomes" "gnomad_genome_coverage" "gnomad_genomes" "mainTranscript" "mpc" "originalAltAlleles" "pos" "primate_ai" "ref" "rsid" "samples_ab" "samples_gq" "samples_no_call" "samples_num_alt" "sortedTranscriptConsequences" "splice_ai" "start" "topmed" "transcriptConsequenceTerms" "transcriptIds" "utrVariantAnnotation" "variantId" "vep" "xpos" "xstart" "xstop") (topmed (GetField topmed (GetField __uid_112 (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)))) (transcriptConsequenceTerms (ToSet (StreamFlatMap __iruid_7670 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_7664))) (ToStream False (GetField consequence_terms (Ref __iruid_7670)))))) (transcriptIds (ToSet (StreamMap __iruid_7671 (ToStream False (GetField sortedTranscriptConsequences (Ref __iruid_7664))) (GetField transcript_id (Ref __iruid_7671))))) (utrVariantAnnotation (ToArray (StreamMap __iruid_7672 (StreamFilter __iruid_7673 (ToStream False (GetField transcript_consequences (GetField vep (Ref __iruid_7664)))) (Let __iruid_7674 (Str "5_prime_UT...") (StreamFold __iruid_7675 __iruid_7676 (ToStream False (GetField consequence_terms (Ref __iruid_7673))) (False) (ApplySpecial lor () Boolean (Ref __iruid_7675) (ApplyComparisonOp EQWithNA (Ref __iruid_7676) (Ref __iruid_7674)))))) (MakeStruct (existing_inframe_oorfs (GetField existing_inframe_oorfs (Ref __iruid_7672))) (existing_outofframe_oorfs (GetField existing_outofframe_oorfs (Ref __iruid_7672))) (existing_uorfs (GetField existing_uorfs (Ref __iruid_7672))) (five_prime_utr_variant_consequence (GetField five_prime_utr_variant_consequence (Ref __iruid_7672))) (five_prime_utr_variant_annotation (GetField five_prime_utr_variant_annotation (Ref __iruid_7672))))))) (variantId (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply concat () String (Apply replace () String (Apply contig () String (Ref __iruid_7665)) (Str "^chr") (Str "")) (Str "-")) (Apply str () String (Apply position () Int32 (Ref __iruid_7665)))) (Str "-")) (ArrayRef (Ref __iruid_7666) (I32 0) (Str " File \"/h..."))) (Str "-")) (ArrayRef (Ref __iruid_7666) (I32 1) (Str " File \"/h...")))) (xpos (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_7677 (Apply replace () String (Apply contig () String (Ref __iruid_7667)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_7677) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_7677) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (Let __iruid_7678 (Apply length () Int32 (Ref __iruid_7677)) (Let __iruid_7679 (If (ApplySpecial lor () Boolean (ApplyComparisonOp LT (I32 0) (ApplyUnaryPrimOp Negate (Ref __iruid_7678))) (ApplyComparisonOp GTEQ (I32 0) (Ref __iruid_7678))) (Die Int32 (Apply concat () String (Str "string ind...") (Apply concat () String (Str "0") (Apply concat () String (Str " / ") (Apply str () String (Ref __iruid_7678)))))) (I32 0)) (Apply substring () String (Ref __iruid_7677) (Ref __iruid_7679) (ApplyBinaryPrimOp Add (Ref __iruid_7679) (I32 1))))) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_7677))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_7667))))) (xstart (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_7680 (Apply replace () String (Apply contig () String (Ref __iruid_7668)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_7680) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_7680) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (Let __iruid_7681 (Apply length () Int32 (Ref __iruid_7680)) (Let __iruid_7682 (If (ApplySpecial lor () Boolean (ApplyComparisonOp LT (I32 0) (ApplyUnaryPrimOp Negate (Ref __iruid_7681))) (ApplyComparisonOp GTEQ (I32 0) (Ref __iruid_7681))) (Die Int32 (Apply concat () String (Str "string ind...") (Apply concat () String (Str "0") (Apply concat () String (Str " / ") (Apply str () String (Ref __iruid_7681)))))) (I32 0)) (Apply substring () String (Ref __iruid_7680) (Ref __iruid_7682) (ApplyBinaryPrimOp Add (Ref __iruid_7682) (I32 1))))) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_7680))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_7668))))) (xstop (ApplyBinaryPrimOp Subtract (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Add (ApplyBinaryPrimOp Multiply (Let __iruid_7683 (Apply replace () String (Apply contig () String (Ref __iruid_7669)) (Str "^chr") (Str "")) (Cast Int64 (If (ApplyComparisonOp EQ (Ref __iruid_7683) (Str "X")) (I32 23) (If (ApplyComparisonOp EQ (Ref __iruid_7683) (Str "Y")) (I32 24) (If (ApplyComparisonOp EQ (Let __iruid_7684 (Apply length () Int32 (Ref __iruid_7683)) (Let __iruid_7685 (If (ApplySpecial lor () Boolean (ApplyComparisonOp LT (I32 0) (ApplyUnaryPrimOp Negate (Ref __iruid_7684))) (ApplyComparisonOp GTEQ (I32 0) (Ref __iruid_7684))) (Die Int32 (Apply concat () String (Str "string ind...") (Apply concat () String (Str "0") (Apply concat () String (Str " / ") (Apply str () String (Ref __iruid_7684)))))) (I32 0)) (Apply substring () String (Ref __iruid_7683) (Ref __iruid_7685) (ApplyBinaryPrimOp Add (Ref __iruid_7685) (I32 1))))) (Str "M")) (I32 25) (Apply toInt32 () Int32 (Ref __iruid_7683))))))) (I64 1000000000)) (Cast Int64 (Apply position () Int32 (Ref __iruid_7669)))) (Cast Int64 (Apply length () Int32 (ArrayRef (GetField alleles (Ref __iruid_7664)) (I32 0) (Str " File \"/h..."))))) (I64 1)))))))))) None (`the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (GetField `the entries! [877f12a8827e18f61222c6c8c5fb04a8]` (In +PCStruct{locus:+PCLocus(GRCh38),alleles:+PCArray[+PCString],rsid:PCString,filters:PCSet[+PCString],vep:PCStruct{assembly_name:PCString,allele_string:PCString,ancestral:PCString,colocated_variants:PCArray[PCStruct{aa_allele:PCString,aa_maf:PFloat64,afr_allele:PCString,afr_maf:PFloat64,allele_string:PCString,amr_allele:PCString,amr_maf:PFloat64,clin_sig:PCArray[PCString],end:PInt32,eas_allele:PCString,eas_maf:PFloat64,ea_allele:PCString,ea_maf:PFloat64,eur_allele:PCString,eur_maf:PFloat64,exac_adj_allele:PCString,exac_adj_maf:PFloat64,exac_allele:PCString,exac_afr_allele:PCString,exac_afr_maf:PFloat64,exac_amr_allele:PCString,exac_amr_maf:PFloat64,exac_eas_allele:PCString,exac_eas_maf:PFloat64,exac_fin_allele:PCString,exac_fin_maf:PFloat64,exac_maf:PFloat64,exac_nfe_allele:PCString,exac_nfe_maf:PFloat64,exac_oth_allele:PCString,exac_oth_maf:PFloat64,exac_sas_allele:PCString,exac_sas_maf:PFloat64,id:PCString,minor_allele:PCString,minor_allele_freq:PFloat64,phenotype_or_disease:PInt32,pubmed:PCArray[PInt32],sas_allele:PCString,sas_maf:PFloat64,somatic:PInt32,start:PInt32,strand:PInt32}],context:PCString,end:PInt32,id:PCString,input:PCString,intergenic_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,variant_allele:PCString}],most_severe_consequence:PCString,motif_feature_consequences:PCArray[PCStruct{allele_num:PInt32,consequence_terms:PCArray[PCString],high_inf_pos:PCString,impact:PCString,minimised:PInt32,motif_feature_id:PCString,motif_name:PCString,motif_pos:PInt32,motif_score_change:PFloat64,strand:PInt32,variant_allele:PCString}],regulatory_feature_consequences:PCArray[PCStruct{allele_num:PInt32,biotype:PCString,consequence_terms:PCArray[PCString],impact:PCString,minimised:PInt32,regulatory_feature_id:PCString,variant_allele:PCString}],seq_region_name:PCString,start:PInt32,strand:PInt32,transcript_consequences:PCArray[PCStruct{existing_inframe_oorfs:PInt32,existing_outofframe_oorfs:PInt32,existing_uorfs:PInt32,five_prime_utr_variant_consequence:PCString,five_prime_utr_variant_annotation:PCString,allele_num:PInt32,amino_acids:PCString,appris:PCString,biotype:PCString,canonical:PInt32,ccds:PCString,cdna_start:PInt32,cdna_end:PInt32,cds_end:PInt32,cds_start:PInt32,codons:PCString,consequence_terms:PCArray[PCString],distance:PInt32,domains:PCArray[PCStruct{db:PCString,name:PCString}],exon:PCString,gene_id:PCString,gene_pheno:PInt32,gene_symbol:PCString,gene_symbol_source:PCString,hgnc_id:PCString,hgvsc:PCString,hgvsp:PCString,hgvs_offset:PInt32,impact:PCString,intron:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,minimised:PInt32,polyphen_prediction:PCString,polyphen_score:PFloat64,protein_end:PInt32,protein_start:PInt32,protein_id:PCString,sift_prediction:PCString,sift_score:PFloat64,strand:PInt32,swissprot:PCString,transcript_id:PCString,trembl:PCString,tsl:PInt32,uniparc:PCString,variant_allele:PCString}],variant_class:PCString},aIndex:+PInt32,AC:PInt32,AF:PFloat64,alt:+PCString,AN:PInt32,cadd:PCStruct{PHRED:PFloat32},clinvar:+PCStruct{allele_id:PInt32,clinical_significance:PCString,gold_stars:PInt32},sortedTranscriptConsequences:PCArray[PCStruct{biotype:PCString,canonical:PInt32,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvsc:PCString,hgvsp:PCString,transcript_id:PCString,amino_acids:PCString,lof:PCString,lof_filter:PCString,lof_flags:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,protein_start:PInt32,sift_prediction:PCString,consequence_terms:PCArray[PCString],domains:PCArray[PCString],major_consequence:PCString,category:PCString,hgvs:PCString,major_consequence_rank:PInt32,transcript_rank:+PInt32}],codingGeneIds:PCSet[PCString],contig:+PCString,dbnsfp:PCStruct{SIFT_pred:PCString,Polyphen2_HVAR_pred:PCString,MutationTaster_pred:PCString,FATHMM_pred:PCString,MetaSVM_pred:PCString,REVEL_score:PCString,GERP_RS:PCString,phastCons100way_vertebrate:PCString},docId:+PCString,domains:PCSet[PCString],eigen:PCStruct{Eigen_phred:PFloat64},end:+PInt32,exac:PCStruct{AF_POPMAX:PFloat64,AF:PFloat64,AC_Adj:PInt32,AC_Het:PInt32,AC_Hom:PInt32,AC_Hemi:PInt32,AN_Adj:PInt32},g1k:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,POPMAX_AF:PFloat64},geneIds:PCSet[PCString],geno2mp:PCStruct{HPO_Count:PInt32},genotypes:+PCArray[+PCStruct{num_alt:PInt32,gq:PInt32,ab:PFloat64,dp:PFloat64,ad:PCString,pl:PCString,sample_id:+PCString}],gnomad_exome_coverage:PFloat64,gnomad_exomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},gnomad_genome_coverage:PFloat32,gnomad_genomes:PCStruct{AF:PFloat64,AN:PInt32,AC:PInt32,Hom:PInt32,AF_POPMAX_OR_GLOBAL:PFloat64,FAF_AF:PFloat64,Hemi:PInt32},mainTranscript:PCStruct{biotype:PCString,canonical:PInt32,category:PCString,cdna_start:PInt32,cdna_end:PInt32,codons:PCString,gene_id:PCString,gene_symbol:PCString,hgvs:PCString,hgvsc:PCString,major_consequence:PCString,major_consequence_rank:PInt32,transcript_id:PCString,amino_acids:PCString,domains:PCString,hgvsp:PCString,lof:PCString,lof_flags:PCString,lof_filter:PCString,lof_info:PCString,polyphen_prediction:PCString,protein_id:PCString,sift_prediction:PCString},mpc:PCStruct{MPC:PCString},originalAltAlleles:+PCArray[+PCString],pos:+PInt32,primate_ai:PCStruct{score:PFloat64},ref:+PCString,samples_ab:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString]},samples_gq:+PCStruct{`0_to_5`:+PCSet[+PCString],`5_to_10`:+PCSet[+PCString],`10_to_15`:+PCSet[+PCString],`15_to_20`:+PCSet[+PCString],`20_to_25`:+PCSet[+PCString],`25_to_30`:+PCSet[+PCString],`30_to_35`:+PCSet[+PCString],`35_to_40`:+PCSet[+PCString],`40_to_45`:+PCSet[+PCString],`45_to_50`:+PCSet[+PCString],`50_to_55`:+PCSet[+PCString],`55_to_60`:+PCSet[+PCString],`60_to_65`:+PCSet[+PCString],`65_to_70`:+PCSet[+PCString],`70_to_75`:+PCSet[+PCString],`75_to_80`:+PCSet[+PCString],`80_to_85`:+PCSet[+PCString],`85_to_90`:+PCSet[+PCString],`90_to_95`:+PCSet[+PCString]},samples_no_call:+PCSet[+PCString],samples_num_alt:+PCStruct{`1`:+PCSet[+PCString],`2`:+PCSet[+PCString]},splice_ai:PCStruct{delta_score:PFloat32},start:+PInt32,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:+PCArray[+PCStruct{AD:PCArray[PInt32],DP:PInt32,GQ:PInt32,GT:PCCall,MIN_DP:PInt32,PGT:PCCall,PID:PCString,PL:PCArray[PInt32],PS:PInt32,RGQ:PInt32,SB:PCArray[PInt32]}],__uid_112:PCStruct{topmed:PCStruct{AC:PInt32,AF:PFloat64,AN:PInt32,Hom:PInt32,Het:PInt32}}} 1)))) (Die Struct{locus:Locus(GRCh38),alleles:Array[String],aIndex:Int32,AC:Int32,AF:Float64,alt:String,AN:Int32,cadd:Struct{PHRED:Float32},clinvar:Struct{allele_id:Int32,clinical_significance:String,gold_stars:Int32},codingGeneIds:Set[String],contig:String,dbnsfp:Struct{SIFT_pred:String,Polyphen2_HVAR_pred:String,MutationTaster_pred:String,FATHMM_pred:String,MetaSVM_pred:String,REVEL_score:String,GERP_RS:String,phastCons100way_vertebrate:String},docId:String,domains:Set[String],eigen:Struct{Eigen_phred:Float64},end:Int32,exac:Struct{AF_POPMAX:Float64,AF:Float64,AC_Adj:Int32,AC_Het:Int32,AC_Hom:Int32,AC_Hemi:Int32,AN_Adj:Int32},filters:Set[String],g1k:Struct{AC:Int32,AF:Float64,AN:Int32,POPMAX_AF:Float64},geneIds:Set[String],geno2mp:Struct{HPO_Count:Int32},genotypes:Array[Struct{num_alt:Int32,gq:Int32,ab:Float64,dp:Float64,ad:String,pl:String,sample_id:String}],gnomad_exome_coverage:Float64,gnomad_exomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},gnomad_genome_coverage:Float32,gnomad_genomes:Struct{AF:Float64,AN:Int32,AC:Int32,Hom:Int32,AF_POPMAX_OR_GLOBAL:Float64,FAF_AF:Float64,Hemi:Int32},mainTranscript:Struct{biotype:String,canonical:Int32,category:String,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvs:String,hgvsc:String,major_consequence:String,major_consequence_rank:Int32,transcript_id:String,amino_acids:String,domains:String,hgvsp:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,polyphen_prediction:String,protein_id:String,sift_prediction:String},mpc:Struct{MPC:String},originalAltAlleles:Array[String],pos:Int32,primate_ai:Struct{score:Float64},ref:String,rsid:String,samples_ab:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String]},samples_gq:Struct{`0_to_5`:Set[String],`5_to_10`:Set[String],`10_to_15`:Set[String],`15_to_20`:Set[String],`20_to_25`:Set[String],`25_to_30`:Set[String],`30_to_35`:Set[String],`35_to_40`:Set[String],`40_to_45`:Set[String],`45_to_50`:Set[String],`50_to_55`:Set[String],`55_to_60`:Set[String],`60_to_65`:Set[String],`65_to_70`:Set[String],`70_to_75`:Set[String],`75_to_80`:Set[String],`80_to_85`:Set[String],`85_to_90`:Set[String],`90_to_95`:Set[String]},samples_no_call:Set[String],samples_num_alt:Struct{`1`:Set[String],`2`:Set[String]},sortedTranscriptConsequences:Array[Struct{biotype:String,canonical:Int32,cdna_start:Int32,cdna_end:Int32,codons:String,gene_id:String,gene_symbol:String,hgvsc:String,hgvsp:String,transcript_id:String,amino_acids:String,lof:String,lof_filter:String,lof_flags:String,lof_info:String,polyphen_prediction:String,protein_id:String,protein_start:Int32,sift_prediction:String,consequence_terms:Array[String],domains:Array[String],major_consequence:String,category:String,hgvs:String,major_consequence_rank:Int32,transcript_rank:Int32}],splice_ai:Struct{delta_score:Float32},start:Int32,topmed:Struct{AC:Int32,AF:Float64,AN:Int32,Hom:Int32,Het:Int32},transcriptConsequenceTerms:Set[String],transcriptIds:Set[String],utrVariantAnnotation:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String}],variantId:String,vep:Struct{assembly_name:String,allele_string:String,ancestral:String,colocated_variants:Array[Struct{aa_allele:String,aa_maf:Float64,afr_allele:String,afr_maf:Float64,allele_string:String,amr_allele:String,amr_maf:Float64,clin_sig:Array[String],end:Int32,eas_allele:String,eas_maf:Float64,ea_allele:String,ea_maf:Float64,eur_allele:String,eur_maf:Float64,exac_adj_allele:String,exac_adj_maf:Float64,exac_allele:String,exac_afr_allele:String,exac_afr_maf:Float64,exac_amr_allele:String,exac_amr_maf:Float64,exac_eas_allele:String,exac_eas_maf:Float64,exac_fin_allele:String,exac_fin_maf:Float64,exac_maf:Float64,exac_nfe_allele:String,exac_nfe_maf:Float64,exac_oth_allele:String,exac_oth_maf:Float64,exac_sas_allele:String,exac_sas_maf:Float64,id:String,minor_allele:String,minor_allele_freq:Float64,phenotype_or_disease:Int32,pubmed:Array[Int32],sas_allele:String,sas_maf:Float64,somatic:Int32,start:Int32,strand:Int32}],context:String,end:Int32,id:String,input:String,intergenic_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],impact:String,minimised:Int32,variant_allele:String}],most_severe_consequence:String,motif_feature_consequences:Array[Struct{allele_num:Int32,consequence_terms:Array[String],high_inf_pos:String,impact:String,minimised:Int32,motif_feature_id:String,motif_name:String,motif_pos:Int32,motif_score_change:Float64,strand:Int32,variant_allele:String}],regulatory_feature_consequences:Array[Struct{allele_num:Int32,biotype:String,consequence_terms:Array[String],impact:String,minimised:Int32,regulatory_feature_id:String,variant_allele:String}],seq_region_name:String,start:Int32,strand:Int32,transcript_consequences:Array[Struct{existing_inframe_oorfs:Int32,existing_outofframe_oorfs:Int32,existing_uorfs:Int32,five_prime_utr_variant_consequence:String,five_prime_utr_variant_annotation:String,allele_num:Int32,amino_acids:String,appris:String,biotype:String,canonical:Int32,ccds:String,cdna_start:Int32,cdna_end:Int32,cds_end:Int32,cds_start:Int32,codons:String,consequence_terms:Array[String],distance:Int32,domains:Array[Struct{db:String,name:String}],exon:String,gene_id:String,gene_pheno:Int32,gene_symbol:String,gene_symbol_source:String,hgnc_id:String,hgvsc:String,hgvsp:String,hgvs_offset:Int32,impact:String,intron:String,lof:String,lof_flags:String,lof_filter:String,lof_info:String,minimised:Int32,polyphen_prediction:String,polyphen_score:Float64,protein_end:Int32,protein_start:Int32,protein_id:String,sift_prediction:String,sift_score:Float64,strand:Int32,swissprot:String,transcript_id:String,trembl:String,tsl:Int32,uniparc:String,variant_allele:String}],variant_class:String},xpos:Int64,xstart:Int64,xstop:Int64,`the entries! [877f12a8827e18f61222c6c8c5fb04a8]`:Array[Struct{AD:Array[Int32],DP:Int32,GQ:Int32,GT:Call,MIN_DP:Int32,PGT:Call,PID:String,PL:Array[Int32],PS:Int32,RGQ:Int32,SB:Array[Int32]}]} (Str "Internal e..."))) 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 56.249ms, total 4m3.0s, tagged coverage 85.5 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.024ms, total 4m3.0s 2022-04-01 03:29:20 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 56.417ms, total 4m3.0s, tagged coverage 85.3 2022-04-01 03:29:20 root: INFO: encoder cache miss (15 hits, 11 misses, 0.577) 2022-04-01 03:29:20 root: INFO: instruction count: 6: __C3397etypeEncode. 2022-04-01 03:29:20 root: INFO: instruction count: 8: __C3397etypeEncode.apply 2022-04-01 03:29:20 root: INFO: instruction count: 116: __C3397etypeEncode.__m3398ENCODE_r_tuple_of_r_stringANDr_stringANDr_stringANDr_stringANDr_stringANDr_stringANDr_stringANDr_stringANDr_stringANDr_stringANDr_stringEND_TO_r_struct_of_r_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryEND 2022-04-01 03:29:20 root: INFO: instruction count: 19: __C3397etypeEncode.__m3399ENCODE_r_binary_TO_r_binary 2022-04-01 03:29:20 MemoryStore: INFO: Block broadcast_29 stored as values in memory (estimated size 208.0 B, free 5.6 GB) 2022-04-01 03:29:20 MemoryStore: INFO: Block broadcast_29_piece0 stored as bytes in memory (estimated size 209.0 B, free 5.6 GB) 2022-04-01 03:29:20 BlockManagerInfo: INFO: Added broadcast_29_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 209.0 B, free: 5.6 GB) 2022-04-01 03:29:20 SparkContext: INFO: Created broadcast 29 from broadcast at SparkBackend.scala:233 2022-04-01 03:29:20 root: INFO: instruction count: 6: __C3215Compiled. 2022-04-01 03:29:20 root: INFO: instruction count: 411: __C3215Compiled.apply 2022-04-01 03:29:20 root: INFO: instruction count: 11: __C3215Compiled.__m3221addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 8: __C3215Compiled.__m3222addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 8: __C3215Compiled.__m3223addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 8: __C3215Compiled.__m3224addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 11: __C3215Compiled.__m3225addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 8: __C3215Compiled.__m3226addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 11: __C3215Compiled.__m3227addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 11: __C3215Compiled.__m3228addIRIntermediate 2022-04-01 03:29:20 root: INFO: 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__C3215Compiled.__m3239addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 11: __C3215Compiled.__m3240addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 11: __C3215Compiled.__m3241addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 11: __C3215Compiled.__m3242addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 11: __C3215Compiled.__m3243addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 11: __C3215Compiled.__m3244addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 11: __C3215Compiled.__m3271addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 15: __C3215Compiled.__m3274setup_jab 2022-04-01 03:29:20 root: INFO: instruction count: 66: __C3215Compiled.__m3275discardNext 2022-04-01 03:29:20 root: INFO: instruction count: 135: __C3215Compiled.__m3276cord 2022-04-01 03:29:20 root: INFO: instruction count: 15: __C3215Compiled.__m3296setup_jab 2022-04-01 03:29:20 root: INFO: instruction count: 66: __C3215Compiled.__m3297discardNext 2022-04-01 03:29:20 root: INFO: instruction count: 15: __C3215Compiled.__m3318setup_jab 2022-04-01 03:29:20 root: INFO: instruction count: 135: __C3215Compiled.__m3330cord 2022-04-01 03:29:20 root: INFO: instruction count: 11: __C3215Compiled.__m3335addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 8: __C3215Compiled.__m3336addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 83: __C3215Compiled.__m3337concat 2022-04-01 03:29:20 root: INFO: instruction count: 102: __C3215Compiled.__m3340replace 2022-04-01 03:29:20 root: INFO: instruction count: 11: __C3215Compiled.__m3343contig 2022-04-01 03:29:20 root: INFO: instruction count: 61: __C3215Compiled.__m3347str 2022-04-01 03:29:20 root: INFO: instruction count: 15: __C3215Compiled.__m3350setup_null 2022-04-01 03:29:20 root: INFO: instruction count: 11: __C3215Compiled.__m3353position 2022-04-01 03:29:20 root: INFO: instruction count: 135: __C3215Compiled.__m3356cord 2022-04-01 03:29:20 root: INFO: instruction count: 26: __C3215Compiled.__m3361length 2022-04-01 03:29:20 root: INFO: instruction count: 26: __C3215Compiled.__m3364cord 2022-04-01 03:29:20 root: INFO: instruction count: 26: __C3215Compiled.__m3365cord 2022-04-01 03:29:20 root: INFO: instruction count: 65: __C3215Compiled.__m3369substring 2022-04-01 03:29:20 root: INFO: instruction count: 27: __C3215Compiled.__m3373toInt32 2022-04-01 03:29:20 root: INFO: instruction count: 8: __C3215Compiled.__m3389addIRIntermediate 2022-04-01 03:29:20 root: INFO: instruction count: 14: __C3215Compiled.setPartitionIndex 2022-04-01 03:29:20 root: INFO: instruction count: 7: __C3215Compiled.addPartitionRegion 2022-04-01 03:29:20 root: INFO: instruction count: 25: __C3215Compiled.__m3393DECODE_r_struct_of_r_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryEND_TO_r_tuple_of_r_stringANDr_stringANDr_stringANDr_stringANDr_stringANDr_stringANDr_stringANDr_stringANDr_stringANDr_stringANDr_stringEND 2022-04-01 03:29:20 root: INFO: instruction count: 81: __C3215Compiled.__m3394read_fields_group_0 2022-04-01 03:29:20 root: INFO: instruction count: 34: __C3215Compiled.__m3395INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:29:20 root: INFO: instruction count: 131: __C3215Compiled.addLiterals 2022-04-01 03:29:20 root: INFO: instruction count: 602: __C3215Compiled.applyregion464_537 2022-04-01 03:29:20 root: INFO: instruction count: 208: __C3215Compiled.applyregion677_684 2022-04-01 03:29:20 root: INFO: instruction count: 169: __C3215Compiled.applyregion781_788 2022-04-01 03:29:20 root: INFO: instruction count: 154: __C3215Compiled.applyregion757_764 2022-04-01 03:29:20 root: INFO: 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instruction count: 136: __C3215Compiled.applyregion168_175 2022-04-01 03:29:20 root: INFO: instruction count: 122: __C3215Compiled.applyregion208_215 2022-04-01 03:29:20 root: INFO: instruction count: 122: __C3215Compiled.applyregion112_119 2022-04-01 03:29:20 root: INFO: instruction count: 122: __C3215Compiled.applyregion32_39 2022-04-01 03:29:20 root: INFO: instruction count: 116: __C3215Compiled.applyregion80_87 2022-04-01 03:29:20 root: INFO: instruction count: 114: __C3215Compiled.applyregion280_288 2022-04-01 03:29:20 root: INFO: instruction count: 102: __C3215Compiled.applyregion192_199 2022-04-01 03:29:20 root: INFO: instruction count: 102: __C3215Compiled.applyregion96_103 2022-04-01 03:29:20 root: INFO: instruction count: 102: __C3215Compiled.applyregion16_23 2022-04-01 03:29:20 root: INFO: instruction count: 102: __C3215Compiled.applyregion56_63 2022-04-01 03:29:20 root: INFO: instruction count: 100: __C3215Compiled.applyregion240_247 2022-04-01 03:29:20 root: INFO: instruction count: 100: __C3215Compiled.applyregion216_223 2022-04-01 03:29:20 root: INFO: instruction count: 100: __C3215Compiled.applyregion144_151 2022-04-01 03:29:20 root: INFO: instruction count: 100: __C3215Compiled.applyregion120_127 2022-04-01 03:29:20 root: INFO: instruction count: 100: __C3215Compiled.applyregion40_47 2022-04-01 03:29:20 root: INFO: instruction count: 98: __C3215Compiled.applyregion8_15 2022-04-01 03:29:20 root: INFO: instruction count: 98: __C3215Compiled.applyregion24_31 2022-04-01 03:29:20 root: INFO: instruction count: 96: __C3215Compiled.applyregion200_207 2022-04-01 03:29:20 root: INFO: instruction count: 96: __C3215Compiled.applyregion104_111 2022-04-01 03:29:20 root: INFO: instruction count: 82: __C3215Compiled.applyregion232_239 2022-04-01 03:29:20 root: INFO: instruction count: 82: __C3215Compiled.applyregion224_231 2022-04-01 03:29:20 root: INFO: instruction count: 82: __C3215Compiled.applyregion136_143 2022-04-01 03:29:20 root: INFO: instruction count: 82: __C3215Compiled.applyregion128_135 2022-04-01 03:29:20 root: INFO: instruction count: 80: __C3215Compiled.applyregion248_255 2022-04-01 03:29:20 root: INFO: instruction count: 80: __C3215Compiled.applyregion152_159 2022-04-01 03:29:20 root: INFO: instruction count: 80: __C3215Compiled.applyregion72_79 2022-04-01 03:29:20 root: INFO: instruction count: 6: __C3400applySpills. 2022-04-01 03:29:20 root: INFO: instruction count: 6: __C3277sort_compare. 2022-04-01 03:29:20 root: INFO: instruction count: 20: __C3277sort_compare.apply 2022-04-01 03:29:20 root: INFO: instruction count: 21: __C3277sort_compare.apply 2022-04-01 03:29:20 root: INFO: instruction count: 61: __C3277sort_compare.__m3279sort 2022-04-01 03:29:20 root: INFO: instruction count: 26: __C3277sort_compare.__m3280cord 2022-04-01 03:29:20 root: INFO: instruction count: 142: __C3277sort_compare.__m3281cord 2022-04-01 03:29:20 root: INFO: instruction count: 6: __C3298sort_compare. 2022-04-01 03:29:20 root: INFO: instruction count: 20: __C3298sort_compare.apply 2022-04-01 03:29:20 root: INFO: instruction count: 21: __C3298sort_compare.apply 2022-04-01 03:29:20 root: INFO: instruction count: 61: __C3298sort_compare.__m3300sort 2022-04-01 03:29:20 root: INFO: instruction count: 26: __C3298sort_compare.__m3301cord 2022-04-01 03:29:20 root: INFO: instruction count: 142: __C3298sort_compare.__m3302cord 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.036ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: optimize optimize: compileLowerer, initial IR: before: IR size 9: (Coalesce (InsertFields (In +PCStruct{gencodeVersion:+PCString,__cols:+PCArray[+PCStruct{s:+PCString}]} 0) ("gencodeVersion" "sourceFilePath" "genomeVersion" "sampleType" "hail_version" "__cols") (sourceFilePath (Str "s3://seqr-...")) (genomeVersion (Str "38")) (sampleType (Str "WGS")) (hail_version (Str "0.2.57"))) (Die Struct{gencodeVersion:String,sourceFilePath:String,genomeVersion:String,sampleType:String,hail_version:String,__cols:Array[Struct{s:String}]} (Str "Internal e..."))) 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- FoldConstants : 0.101ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.031ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- Simplify : 0.112ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardLets : 0.116ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.022ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.411ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation -- Optimize : 0.945ms, total 4m4.5s, tagged coverage 83.9 2022-04-01 03:29:21 root: INFO: optimize optimize: compileLowerer, initial IR: after: IR size 9: (Coalesce (InsertFields (In +PCStruct{gencodeVersion:+PCString,__cols:+PCArray[+PCStruct{s:+PCString}]} 0) ("gencodeVersion" "sourceFilePath" "genomeVersion" "sampleType" "hail_version" "__cols") (sourceFilePath (Str "s3://seqr-...")) (genomeVersion (Str "38")) (sampleType (Str "WGS")) (hail_version (Str "0.2.57"))) (Die Struct{gencodeVersion:String,sourceFilePath:String,genomeVersion:String,sampleType:String,hail_version:String,__cols:Array[Struct{s:String}]} (Str "Internal e..."))) 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- LoweringTransformation : 1.234ms, total 4m4.5s, tagged coverage 64.3 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR -- Verify : 0.003ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, initial IR : 1.399ms, total 4m4.5s, tagged coverage 59.5 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.005ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- LoweringTransformation : 0.012ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR -- Verify : 0.003ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- InlineApplyIR : 0.055ms, total 4m4.5s, tagged coverage 37.0 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.001ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: before: IR size 9: (Coalesce (InsertFields (In +PCStruct{gencodeVersion:+PCString,__cols:+PCArray[+PCStruct{s:+PCString}]} 0) ("gencodeVersion" "sourceFilePath" "genomeVersion" "sampleType" "hail_version" "__cols") (sourceFilePath (Str "s3://seqr-...")) (genomeVersion (Str "38")) (sampleType (Str "WGS")) (hail_version (Str "0.2.57"))) (Die Struct{gencodeVersion:String,sourceFilePath:String,genomeVersion:String,sampleType:String,hail_version:String,__cols:Array[Struct{s:String}]} (Str "Internal e..."))) 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- FoldConstants : 0.037ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.028ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- Simplify : 0.046ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardLets : 0.101ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.017ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.151ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation -- Optimize : 0.486ms, total 4m4.5s, tagged coverage 78.2 2022-04-01 03:29:21 root: INFO: optimize optimize: compileLowerer, after InlineApplyIR: after: IR size 9: (Coalesce (InsertFields (In +PCStruct{gencodeVersion:+PCString,__cols:+PCArray[+PCStruct{s:+PCString}]} 0) ("gencodeVersion" "sourceFilePath" "genomeVersion" "sampleType" "hail_version" "__cols") (sourceFilePath (Str "s3://seqr-...")) (genomeVersion (Str "38")) (sampleType (Str "WGS")) (hail_version (Str "0.2.57"))) (Die Struct{gencodeVersion:String,sourceFilePath:String,genomeVersion:String,sampleType:String,hail_version:String,__cols:Array[Struct{s:String}]} (Str "Internal e..."))) 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- LoweringTransformation : 0.659ms, total 4m4.5s, tagged coverage 57.6 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR -- Verify : 0.002ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after InlineApplyIR : 0.725ms, total 4m4.5s, tagged coverage 52.8 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.003ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- LoweringTransformation : 0.189ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs -- Verify : 0.005ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- LowerArrayAggsToRunAggs : 0.247ms, total 4m4.5s, tagged coverage 80.0 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.002ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: before: IR size 9: (Coalesce (InsertFields (In +PCStruct{gencodeVersion:+PCString,__cols:+PCArray[+PCStruct{s:+PCString}]} 0) ("gencodeVersion" "sourceFilePath" "genomeVersion" "sampleType" "hail_version" "__cols") (sourceFilePath (Str "s3://seqr-...")) (genomeVersion (Str "38")) (sampleType (Str "WGS")) (hail_version (Str "0.2.57"))) (Die Struct{gencodeVersion:String,sourceFilePath:String,genomeVersion:String,sampleType:String,hail_version:String,__cols:Array[Struct{s:String}]} (Str "Internal e..."))) 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- FoldConstants : 0.049ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ExtractIntervalFilters : 0.023ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- Simplify : 0.038ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardLets : 0.096ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- ForwardRelationalLets : 0.016ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize -- PruneDeadFields : 0.146ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation -- Optimize : 0.478ms, total 4m4.5s, tagged coverage 76.9 2022-04-01 03:29:21 root: INFO: optimize optimize: compileLowerer, after LowerArrayAggsToRunAggs: after: IR size 9: (Coalesce (InsertFields (In +PCStruct{gencodeVersion:+PCString,__cols:+PCArray[+PCStruct{s:+PCString}]} 0) ("gencodeVersion" "sourceFilePath" "genomeVersion" "sampleType" "hail_version" "__cols") (sourceFilePath (Str "s3://seqr-...")) (genomeVersion (Str "38")) (sampleType (Str "WGS")) (hail_version (Str "0.2.57"))) (Die Struct{gencodeVersion:String,sourceFilePath:String,genomeVersion:String,sampleType:String,hail_version:String,__cols:Array[Struct{s:String}]} (Str "Internal e..."))) 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- LoweringTransformation : 0.745ms, total 4m4.5s, tagged coverage 49.3 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs -- Verify : 0.002ms, total 4m4.5s 2022-04-01 03:29:21 root: INFO: Timer: Time taken for InterpretNonCompilable -- LoweringTransformation -- optimize: compileLowerer, after LowerArrayAggsToRunAggs : 0.813ms, total 4m4.5s, tagged coverage 45.7 2022-04-01 03:29:21 root: INFO: encoder cache miss (15 hits, 12 misses, 0.556) 2022-04-01 03:29:21 root: INFO: instruction count: 6: __C3510etypeEncode. 2022-04-01 03:29:21 root: INFO: instruction count: 8: __C3510etypeEncode.apply 2022-04-01 03:29:21 root: INFO: instruction count: 56: __C3510etypeEncode.__m3511ENCODE_r_tuple_of_r_stringANDr_stringANDr_stringANDr_stringANDr_stringEND_TO_r_struct_of_r_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryEND 2022-04-01 03:29:21 root: INFO: instruction count: 19: __C3510etypeEncode.__m3512ENCODE_r_binary_TO_r_binary 2022-04-01 03:29:21 MemoryStore: INFO: Block broadcast_30 stored as values in memory (estimated size 192.0 B, free 5.6 GB) 2022-04-01 03:29:21 MemoryStore: INFO: Block broadcast_30_piece0 stored as bytes in memory (estimated size 193.0 B, free 5.6 GB) 2022-04-01 03:29:21 BlockManagerInfo: INFO: Added broadcast_30_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 193.0 B, free: 5.6 GB) 2022-04-01 03:29:21 SparkContext: INFO: Created broadcast 30 from broadcast at SparkBackend.scala:233 2022-04-01 03:29:21 root: INFO: instruction count: 6: __C3493Compiled. 2022-04-01 03:29:21 root: INFO: instruction count: 123: __C3493Compiled.apply 2022-04-01 03:29:21 root: INFO: instruction count: 8: __C3493Compiled.__m3497addIRIntermediate 2022-04-01 03:29:21 root: INFO: instruction count: 8: __C3493Compiled.__m3502addIRIntermediate 2022-04-01 03:29:21 root: INFO: instruction count: 14: __C3493Compiled.setPartitionIndex 2022-04-01 03:29:21 root: INFO: instruction count: 7: __C3493Compiled.addPartitionRegion 2022-04-01 03:29:21 root: INFO: instruction count: 25: __C3493Compiled.__m3506DECODE_r_struct_of_r_binaryANDr_binaryANDr_binaryANDr_binaryANDr_binaryEND_TO_r_tuple_of_r_stringANDr_stringANDr_stringANDr_stringANDr_stringEND 2022-04-01 03:29:21 root: INFO: instruction count: 39: __C3493Compiled.__m3507read_fields_group_0 2022-04-01 03:29:21 root: INFO: instruction count: 34: __C3493Compiled.__m3508INPLACE_DECODE_r_binary_TO_r_binary 2022-04-01 03:29:21 root: INFO: instruction count: 77: __C3493Compiled.addLiterals 2022-04-01 03:29:21 ClientConfigurationFactory: INFO: Set initial getObject socket timeout to 2000 ms. 2022-04-01 03:29:23 root: INFO: encoder cache miss (15 hits, 13 misses, 0.536) 2022-04-01 03:29:23 root: INFO: instruction count: 6: __C3513etypeEncode. 2022-04-01 03:29:23 root: INFO: instruction count: 8: __C3513etypeEncode.apply 2022-04-01 03:29:23 root: INFO: instruction count: 508: __C3513etypeEncode.__m3514ENCODE_r_tuple_of_r_locusANDr_array_of_r_stringANDr_int32ANDo_int32ANDo_float64ANDr_stringANDo_int32ANDo_tuple_of_o_float32ENDANDr_tuple_of_o_int32ANDo_stringANDo_int32ENDANDo_set_of_o_stringANDr_stringANDo_tuple_of_o_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDANDr_stringANDo_set_of_o_stringANDo_tuple_of_o_float64ENDANDr_int32ANDo_tuple_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_set_of_r_stringANDo_tuple_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_set_of_o_stringANDo_tuple_of_o_int32ENDANDr_array_of_r_tuple_of_o_int32ANDo_int32ANDo_float64ANDo_float64ANDo_stringANDo_stringANDr_stringENDANDo_float64ANDo_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_float32ANDo_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_tuple_of_o_stringANDo_int32ANDo_stringANDo_int32ANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDANDo_tuple_of_o_stringENDANDr_array_of_r_stringANDr_int32ANDo_tuple_of_o_float64ENDANDr_stringANDo_stringANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringENDANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringENDANDr_set_of_r_stringANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringENDANDo_array_of_o_tuple_of_o_stringANDo_int32ANDo_int32ANDo_int32ANDo_stringAN 2022-04-01 03:29:23 root: INFO: instruction count: 26: __C3513etypeEncode.__m3515ENCODE_r_tuple_of_r_binaryANDr_int32END_TO_r_struct_of_r_binaryANDr_int32END 2022-04-01 03:29:23 root: INFO: instruction count: 19: __C3513etypeEncode.__m3516ENCODE_r_binary_TO_r_binary 2022-04-01 03:29:23 root: INFO: instruction count: 7: __C3513etypeEncode.__m3517ENCODE_r_int32_TO_r_int32 2022-04-01 03:29:23 root: INFO: instruction count: 57: __C3513etypeEncode.__m3518ENCODE_r_array_of_r_binary_TO_r_array_of_r_binary 2022-04-01 03:29:23 root: INFO: instruction count: 7: __C3513etypeEncode.__m3519ENCODE_o_int32_TO_o_int32 2022-04-01 03:29:23 root: INFO: instruction count: 7: __C3513etypeEncode.__m3520ENCODE_o_float64_TO_o_float64 2022-04-01 03:29:23 root: INFO: instruction count: 39: __C3513etypeEncode.__m3521ENCODE_o_tuple_of_o_float32END_TO_o_struct_of_o_float32END 2022-04-01 03:29:23 root: INFO: instruction count: 7: __C3513etypeEncode.__m3522ENCODE_o_float32_TO_o_float32 2022-04-01 03:29:23 root: INFO: instruction count: 81: __C3513etypeEncode.__m3523ENCODE_r_tuple_of_o_int32ANDo_binaryANDo_int32END_TO_r_struct_of_o_int32ANDo_binaryANDo_int32END 2022-04-01 03:29:23 root: INFO: instruction count: 19: __C3513etypeEncode.__m3524ENCODE_o_binary_TO_o_binary 2022-04-01 03:29:23 root: INFO: instruction count: 126: __C3513etypeEncode.__m3525ENCODE_o_array_of_o_binary_TO_o_array_of_o_binary 2022-04-01 03:29:23 root: INFO: instruction count: 186: __C3513etypeEncode.__m3526ENCODE_o_tuple_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND_TO_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 39: __C3513etypeEncode.__m3527ENCODE_o_tuple_of_o_float64END_TO_o_struct_of_o_float64END 2022-04-01 03:29:23 root: INFO: instruction count: 165: __C3513etypeEncode.__m3528ENCODE_o_tuple_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:29:23 root: INFO: instruction count: 57: __C3513etypeEncode.__m3529ENCODE_o_array_of_r_binary_TO_o_array_of_r_binary 2022-04-01 03:29:23 root: INFO: instruction count: 102: __C3513etypeEncode.__m3530ENCODE_o_tuple_of_o_int32ANDo_float64ANDo_int32ANDo_float64END_TO_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_float64END 2022-04-01 03:29:23 root: INFO: instruction count: 39: __C3513etypeEncode.__m3531ENCODE_o_tuple_of_o_int32END_TO_o_struct_of_o_int32END 2022-04-01 03:29:23 root: INFO: instruction count: 53: __C3513etypeEncode.__m3532ENCODE_r_array_of_r_tuple_of_o_int32ANDo_int32ANDo_float64ANDo_float64ANDo_binaryANDo_binaryANDr_binaryEND_TO_r_array_of_r_struct_of_o_int32ANDo_int32ANDo_float64ANDo_float64ANDo_binaryANDo_binaryANDr_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 154: __C3513etypeEncode.__m3533ENCODE_r_tuple_of_o_int32ANDo_int32ANDo_float64ANDo_float64ANDo_binaryANDo_binaryANDr_binaryEND_TO_r_struct_of_o_int32ANDo_int32ANDo_float64ANDo_float64ANDo_binaryANDo_binaryANDr_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 165: __C3513etypeEncode.__m3534ENCODE_o_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END_TO_o_struct_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32END 2022-04-01 03:29:23 root: INFO: instruction count: 505: __C3513etypeEncode.__m3535ENCODE_o_tuple_of_o_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND_TO_o_struct_of_o_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 39: __C3513etypeEncode.__m3536ENCODE_o_tuple_of_o_binaryEND_TO_o_struct_of_o_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 39: __C3513etypeEncode.__m3537ENCODE_o_tuple_of_o_float64END_TO_o_struct_of_o_float64END 2022-04-01 03:29:23 root: INFO: instruction count: 96: __C3513etypeEncode.__m3538ENCODE_r_tuple_of_r_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryEND_TO_r_struct_of_r_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 196: __C3513etypeEncode.__m3539ENCODE_r_tuple_of_r_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryEND_TO_r_struct_of_r_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryANDr_array_of_r_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 26: __C3513etypeEncode.__m3540ENCODE_r_tuple_of_r_array_of_r_binaryANDr_array_of_r_binaryEND_TO_r_struct_of_r_array_of_r_binaryANDr_array_of_r_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 122: __C3513etypeEncode.__m3541ENCODE_o_array_of_o_tuple_of_o_binaryANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDr_int32END_TO_o_array_of_o_struct_of_o_binaryANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDr_int32END 2022-04-01 03:29:23 root: INFO: instruction count: 511: __C3513etypeEncode.__m3542ENCODE_o_tuple_of_o_binaryANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDr_int32END_TO_o_struct_of_o_binaryANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDr_int32END 2022-04-01 03:29:23 root: INFO: instruction count: 39: __C3513etypeEncode.__m3543ENCODE_o_tuple_of_o_float32END_TO_o_struct_of_o_float32END 2022-04-01 03:29:23 root: INFO: instruction count: 123: __C3513etypeEncode.__m3544ENCODE_o_tuple_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_int32ANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:29:23 root: INFO: instruction count: 53: __C3513etypeEncode.__m3545ENCODE_o_array_of_r_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryEND_TO_o_array_of_r_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 123: __C3513etypeEncode.__m3546ENCODE_r_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryEND_TO_r_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 379: __C3513etypeEncode.__m3547ENCODE_o_tuple_of_o_binaryANDo_binaryANDo_binaryANDo_array_of_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_array_of_o_tuple_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryENDANDo_binaryANDo_array_of_o_tuple_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_float64ANDo_int32ANDo_binaryENDANDo_array_of_o_tuple_of_o_int32ANDo_binaryANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDANDo_binaryANDo_int32ANDo_int32ANDo_array_of_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDANDo_binaryEND_TO_o_struct_of_o_binaryANDo_binaryANDo_binaryANDo_array_of_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryA 2022-04-01 03:29:23 root: INFO: instruction count: 122: __C3513etypeEncode.__m3548ENCODE_o_array_of_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_array_of_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:29:23 root: INFO: instruction count: 484: __C3513etypeEncode.__m3549ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END 2022-04-01 03:29:23 root: INFO: instruction count: 126: __C3513etypeEncode.__m3550ENCODE_o_array_of_o_int32_TO_o_array_of_o_int32 2022-04-01 03:29:23 root: INFO: instruction count: 122: __C3513etypeEncode.__m3551ENCODE_o_array_of_o_tuple_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryEND_TO_o_array_of_o_struct_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 123: __C3513etypeEncode.__m3552ENCODE_o_tuple_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryEND_TO_o_struct_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 122: __C3513etypeEncode.__m3553ENCODE_o_array_of_o_tuple_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_float64ANDo_int32ANDo_binaryEND_TO_o_array_of_o_struct_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_float64ANDo_int32ANDo_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 253: __C3513etypeEncode.__m3554ENCODE_o_tuple_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_float64ANDo_int32ANDo_binaryEND_TO_o_struct_of_o_int32ANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_float64ANDo_int32ANDo_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 122: __C3513etypeEncode.__m3555ENCODE_o_array_of_o_tuple_of_o_int32ANDo_binaryANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_array_of_o_struct_of_o_int32ANDo_binaryANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 165: __C3513etypeEncode.__m3556ENCODE_o_tuple_of_o_int32ANDo_binaryANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_binaryANDo_array_of_o_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 122: __C3513etypeEncode.__m3557ENCODE_o_array_of_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_array_of_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 493: __C3513etypeEncode.__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 122: __C3513etypeEncode.__m3559ENCODE_o_array_of_o_tuple_of_o_binaryANDo_binaryEND_TO_o_array_of_o_struct_of_o_binaryANDo_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 60: __C3513etypeEncode.__m3560ENCODE_o_tuple_of_o_binaryANDo_binaryEND_TO_o_struct_of_o_binaryANDo_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 7: __C3513etypeEncode.__m3561ENCODE_r_int64_TO_r_int64 2022-04-01 03:29:23 root: INFO: instruction count: 409: __C3513etypeEncode.__m3514ENCODE_r_tuple_of_r_locusANDr_array_of_r_stringANDr_int32ANDo_int32ANDo_float64ANDr_stringANDo_int32ANDo_tuple_of_o_float32ENDANDr_tuple_of_o_int32ANDo_stringANDo_int32ENDANDo_set_of_o_stringANDr_stringANDo_tuple_of_o_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDANDr_stringANDo_set_of_o_stringANDo_tuple_of_o_float64ENDANDr_int32ANDo_tuple_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_set_of_r_stringANDo_tuple_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_set_of_o_stringANDo_tuple_of_o_int32ENDANDr_array_of_r_tuple_of_o_int32ANDo_int32ANDo_float64ANDo_float64ANDo_stringANDo_stringANDr_stringENDANDo_float64ANDo_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_float32ANDo_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_tuple_of_o_stringANDo_int32ANDo_stringANDo_int32ANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDANDo_tuple_of_o_stringENDANDr_array_of_r_stringANDr_int32ANDo_tuple_of_o_float64ENDANDr_stringANDo_stringANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringENDANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringENDANDr_set_of_r_stringANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringENDANDo_array_of_o_tuple_of_o_stringANDo_int32ANDo_int32ANDo_int32ANDo_stringANregion0_5 2022-04-01 03:29:23 root: INFO: instruction count: 93: __C3513etypeEncode.__m3514ENCODE_r_tuple_of_r_locusANDr_array_of_r_stringANDr_int32ANDo_int32ANDo_float64ANDr_stringANDo_int32ANDo_tuple_of_o_float32ENDANDr_tuple_of_o_int32ANDo_stringANDo_int32ENDANDo_set_of_o_stringANDr_stringANDo_tuple_of_o_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDANDr_stringANDo_set_of_o_stringANDo_tuple_of_o_float64ENDANDr_int32ANDo_tuple_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_set_of_r_stringANDo_tuple_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_set_of_o_stringANDo_tuple_of_o_int32ENDANDr_array_of_r_tuple_of_o_int32ANDo_int32ANDo_float64ANDo_float64ANDo_stringANDo_stringANDr_stringENDANDo_float64ANDo_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_float32ANDo_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_tuple_of_o_stringANDo_int32ANDo_stringANDo_int32ANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDANDo_tuple_of_o_stringENDANDr_array_of_r_stringANDr_int32ANDo_tuple_of_o_float64ENDANDr_stringANDo_stringANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringENDANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringENDANDr_set_of_r_stringANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringENDANDo_array_of_o_tuple_of_o_stringANDo_int32ANDo_int32ANDo_int32ANDo_stringANregion78_83 2022-04-01 03:29:23 root: INFO: instruction count: 92: __C3513etypeEncode.__m3514ENCODE_r_tuple_of_r_locusANDr_array_of_r_stringANDr_int32ANDo_int32ANDo_float64ANDr_stringANDo_int32ANDo_tuple_of_o_float32ENDANDr_tuple_of_o_int32ANDo_stringANDo_int32ENDANDo_set_of_o_stringANDr_stringANDo_tuple_of_o_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDANDr_stringANDo_set_of_o_stringANDo_tuple_of_o_float64ENDANDr_int32ANDo_tuple_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_set_of_r_stringANDo_tuple_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_set_of_o_stringANDo_tuple_of_o_int32ENDANDr_array_of_r_tuple_of_o_int32ANDo_int32ANDo_float64ANDo_float64ANDo_stringANDo_stringANDr_stringENDANDo_float64ANDo_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_float32ANDo_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_tuple_of_o_stringANDo_int32ANDo_stringANDo_int32ANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDANDo_tuple_of_o_stringENDANDr_array_of_r_stringANDr_int32ANDo_tuple_of_o_float64ENDANDr_stringANDo_stringANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringENDANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringENDANDr_set_of_r_stringANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringENDANDo_array_of_o_tuple_of_o_stringANDo_int32ANDo_int32ANDo_int32ANDo_stringANregion60_65 2022-04-01 03:29:23 root: INFO: instruction count: 84: __C3513etypeEncode.__m3514ENCODE_r_tuple_of_r_locusANDr_array_of_r_stringANDr_int32ANDo_int32ANDo_float64ANDr_stringANDo_int32ANDo_tuple_of_o_float32ENDANDr_tuple_of_o_int32ANDo_stringANDo_int32ENDANDo_set_of_o_stringANDr_stringANDo_tuple_of_o_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDANDr_stringANDo_set_of_o_stringANDo_tuple_of_o_float64ENDANDr_int32ANDo_tuple_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_set_of_r_stringANDo_tuple_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_set_of_o_stringANDo_tuple_of_o_int32ENDANDr_array_of_r_tuple_of_o_int32ANDo_int32ANDo_float64ANDo_float64ANDo_stringANDo_stringANDr_stringENDANDo_float64ANDo_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_float32ANDo_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_tuple_of_o_stringANDo_int32ANDo_stringANDo_int32ANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDANDo_tuple_of_o_stringENDANDr_array_of_r_stringANDr_int32ANDo_tuple_of_o_float64ENDANDr_stringANDo_stringANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringENDANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringENDANDr_set_of_r_stringANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringENDANDo_array_of_o_tuple_of_o_stringANDo_int32ANDo_int32ANDo_int32ANDo_stringANregion54_59 2022-04-01 03:29:23 root: INFO: instruction count: 85: __C3513etypeEncode.__m3542ENCODE_o_tuple_of_o_binaryANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDr_int32END_TO_o_struct_of_o_binaryANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDr_int32ENDregion0_5 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3542ENCODE_o_tuple_of_o_binaryANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDr_int32END_TO_o_struct_of_o_binaryANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDr_int32ENDregion66_71 2022-04-01 03:29:23 root: INFO: instruction count: 85: __C3513etypeEncode.__m3549ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion0_5 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3549ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion120_125 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3549ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion114_119 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3549ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion108_113 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3549ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion102_107 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3549ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion96_101 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3549ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion90_95 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3549ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion84_89 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3549ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion78_83 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3549ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion72_77 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3549ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion66_71 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3549ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDregion60_65 2022-04-01 03:29:23 root: INFO: instruction count: 85: __C3513etypeEncode.__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion0_5 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion138_143 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion132_137 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion126_131 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion120_125 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion114_119 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion108_113 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion102_107 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion96_101 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion90_95 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion84_89 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion78_83 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion72_77 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion66_71 2022-04-01 03:29:23 root: INFO: instruction count: 56: __C3513etypeEncode.__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDregion60_65 2022-04-01 03:29:23 root: INFO: instruction count: 6: __C3562__m3514ENCODE_r_tuple_of_r_locusANDr_array_of_r_stringANDr_int32ANDo_int32ANDo_float64ANDr_stringANDo_int32ANDo_tuple_of_o_float32ENDANDr_tuple_of_o_int32ANDo_stringANDo_int32ENDANDo_set_of_o_stringANDr_stringANDo_tuple_of_o_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDANDr_stringANDo_set_of_o_stringANDo_tuple_of_o_float64ENDANDr_int32ANDo_tuple_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_set_of_r_stringANDo_tuple_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_set_of_o_stringANDo_tuple_of_o_int32ENDANDr_array_of_r_tuple_of_o_int32ANDo_int32ANDo_float64ANDo_float64ANDo_stringANDo_stringANDr_stringENDANDo_float64ANDo_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_float32ANDo_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_tuple_of_o_stringANDo_int32ANDo_stringANDo_int32ANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDANDo_tuple_of_o_stringENDANDr_array_of_r_stringANDr_int32ANDo_tuple_of_o_float64ENDANDr_stringANDo_stringANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringENDANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringENDANDr_set_of_r_stringANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringENDANDo_array_of_o_tuple_of_o_stringANDo_int32ANDo_int32ANDo_int32ANDo_stringANSpills. 2022-04-01 03:29:23 root: INFO: instruction count: 6: __C3571__m3542ENCODE_o_tuple_of_o_binaryANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDr_int32END_TO_o_struct_of_o_binaryANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_array_of_o_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDr_int32ENDSpills. 2022-04-01 03:29:23 root: INFO: instruction count: 6: __C3578__m3549ENCODE_o_tuple_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32END_TO_o_struct_of_o_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_array_of_o_binaryANDo_int32ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_float64ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_array_of_o_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_int32ENDSpills. 2022-04-01 03:29:23 root: INFO: instruction count: 6: __C3595__m3558ENCODE_o_tuple_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_tuple_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryEND_TO_o_struct_of_o_int32ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_binaryANDo_int32ANDo_array_of_o_struct_of_o_binaryANDo_binaryENDANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_float64ANDo_int32ANDo_int32ANDo_binaryANDo_binaryANDo_float64ANDo_int32ANDo_binaryANDo_binaryANDo_binaryANDo_int32ANDo_binaryANDo_binaryENDSpills. 2022-04-01 03:29:23 root: INFO: encoder cache miss (15 hits, 14 misses, 0.517) 2022-04-01 03:29:23 root: INFO: instruction count: 6: __C3615etypeEncode. 2022-04-01 03:29:23 root: INFO: instruction count: 8: __C3615etypeEncode.apply 2022-04-01 03:29:23 root: INFO: instruction count: 16: __C3615etypeEncode.__m3616ENCODE_r_tuple_of_r_locusANDr_array_of_r_stringANDr_int32ANDo_int32ANDo_float64ANDr_stringANDo_int32ANDo_tuple_of_o_float32ENDANDr_tuple_of_o_int32ANDo_stringANDo_int32ENDANDo_set_of_o_stringANDr_stringANDo_tuple_of_o_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDANDr_stringANDo_set_of_o_stringANDo_tuple_of_o_float64ENDANDr_int32ANDo_tuple_of_o_float64ANDo_float64ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ENDANDo_set_of_r_stringANDo_tuple_of_o_int32ANDo_float64ANDo_int32ANDo_float64ENDANDo_set_of_o_stringANDo_tuple_of_o_int32ENDANDr_array_of_r_tuple_of_o_int32ANDo_int32ANDo_float64ANDo_float64ANDo_stringANDo_stringANDr_stringENDANDo_float64ANDo_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_float32ANDo_tuple_of_o_float64ANDo_int32ANDo_int32ANDo_int32ANDo_float64ANDo_float64ANDo_int32ENDANDo_tuple_of_o_stringANDo_int32ANDo_stringANDo_int32ANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_int32ANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringANDo_stringENDANDo_tuple_of_o_stringENDANDr_array_of_r_stringANDr_int32ANDo_tuple_of_o_float64ENDANDr_stringANDo_stringANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringENDANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringANDr_set_of_r_stringENDANDr_set_of_r_stringANDr_tuple_of_r_set_of_r_stringANDr_set_of_r_stringENDANDo_array_of_o_tuple_of_o_stringANDo_int32ANDo_int32ANDo_int32ANDo_stringAN 2022-04-01 03:29:23 root: INFO: instruction count: 53: __C3615etypeEncode.__m3617ENCODE_r_array_of_r_tuple_of_o_array_of_o_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_int32ANDo_int32ANDo_int32ANDo_array_of_o_int32END_TO_r_array_of_r_struct_of_o_array_of_o_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_int32ANDo_int32ANDo_int32ANDo_array_of_o_int32END 2022-04-01 03:29:23 root: INFO: instruction count: 253: __C3615etypeEncode.__m3618ENCODE_r_tuple_of_o_array_of_o_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_int32ANDo_int32ANDo_int32ANDo_array_of_o_int32END_TO_r_struct_of_o_array_of_o_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_int32ANDo_binaryANDo_array_of_o_int32ANDo_int32ANDo_int32ANDo_array_of_o_int32END 2022-04-01 03:29:23 root: INFO: instruction count: 126: __C3615etypeEncode.__m3619ENCODE_o_array_of_o_int32_TO_o_array_of_o_int32 2022-04-01 03:29:23 root: INFO: instruction count: 7: __C3615etypeEncode.__m3620ENCODE_o_int32_TO_o_int32 2022-04-01 03:29:23 root: INFO: instruction count: 19: __C3615etypeEncode.__m3621ENCODE_o_binary_TO_o_binary 2022-04-01 03:29:23 root: INFO: instruction count: 6: __C3622indexwriter. 2022-04-01 03:29:23 root: INFO: instruction count: 241: __C3622indexwriter.apply 2022-04-01 03:29:23 root: INFO: instruction count: 457: __C3622indexwriter.__m3631writeInternalNode 2022-04-01 03:29:23 root: INFO: instruction count: 16: __C3622indexwriter.__m3632ENCODE_o_tuple_of_r_array_of_r_tuple_of_r_int64ANDr_int64ANDr_tuple_of_r_locusANDr_array_of_r_stringENDANDr_int64ANDr_tuple_of_o_int64ENDENDEND_TO_o_struct_of_r_array_of_r_struct_of_r_int64ANDr_int64ANDr_struct_of_r_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryENDANDr_int64ANDr_struct_of_o_int64ENDENDEND 2022-04-01 03:29:23 root: INFO: instruction count: 53: __C3622indexwriter.__m3633ENCODE_r_array_of_r_tuple_of_r_int64ANDr_int64ANDr_tuple_of_r_tuple_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryENDANDr_int64ANDr_tuple_of_o_int64ENDEND_TO_r_array_of_r_struct_of_r_int64ANDr_int64ANDr_struct_of_r_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryENDANDr_int64ANDr_struct_of_o_int64ENDEND 2022-04-01 03:29:23 root: INFO: instruction count: 48: __C3622indexwriter.__m3634ENCODE_r_tuple_of_r_int64ANDr_int64ANDr_tuple_of_r_tuple_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryENDANDr_int64ANDr_tuple_of_o_int64ENDEND_TO_r_struct_of_r_int64ANDr_int64ANDr_struct_of_r_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryENDANDr_int64ANDr_struct_of_o_int64ENDEND 2022-04-01 03:29:23 root: INFO: instruction count: 7: __C3622indexwriter.__m3635ENCODE_r_int64_TO_r_int64 2022-04-01 03:29:23 root: INFO: instruction count: 22: __C3622indexwriter.__m3636ENCODE_r_tuple_of_r_tuple_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryEND_TO_r_struct_of_r_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryEND 2022-04-01 03:29:23 root: INFO: instruction count: 26: __C3622indexwriter.__m3637ENCODE_r_tuple_of_r_binaryANDr_int32END_TO_r_struct_of_r_binaryANDr_int32END 2022-04-01 03:29:23 root: INFO: instruction count: 19: __C3622indexwriter.__m3638ENCODE_r_binary_TO_r_binary 2022-04-01 03:29:23 root: INFO: instruction count: 7: __C3622indexwriter.__m3639ENCODE_r_int32_TO_r_int32 2022-04-01 03:29:23 root: INFO: instruction count: 57: __C3622indexwriter.__m3640ENCODE_r_array_of_r_binary_TO_r_array_of_r_binary 2022-04-01 03:29:23 root: INFO: instruction count: 39: __C3622indexwriter.__m3641ENCODE_r_tuple_of_o_int64END_TO_r_struct_of_o_int64END 2022-04-01 03:29:23 root: INFO: instruction count: 7: __C3622indexwriter.__m3642ENCODE_o_int64_TO_o_int64 2022-04-01 03:29:23 root: INFO: instruction count: 386: __C3622indexwriter.__m3647writeLeafNode 2022-04-01 03:29:23 root: INFO: instruction count: 26: __C3622indexwriter.__m3648ENCODE_o_tuple_of_r_int64ANDr_array_of_r_tuple_of_r_tuple_of_r_locusANDr_array_of_r_stringENDANDr_int64ANDr_tuple_of_o_int64ENDENDEND_TO_o_struct_of_r_int64ANDr_array_of_r_struct_of_r_struct_of_r_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryENDANDr_int64ANDr_struct_of_o_int64ENDENDEND 2022-04-01 03:29:23 root: INFO: instruction count: 53: __C3622indexwriter.__m3649ENCODE_r_array_of_r_tuple_of_r_tuple_of_r_tuple_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryENDANDr_int64ANDr_tuple_of_o_int64ENDEND_TO_r_array_of_r_struct_of_r_struct_of_r_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryENDANDr_int64ANDr_struct_of_o_int64ENDEND 2022-04-01 03:29:23 root: INFO: instruction count: 28: __C3622indexwriter.__m3650ENCODE_r_tuple_of_r_tuple_of_r_tuple_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryENDANDr_int64ANDr_tuple_of_o_int64ENDEND_TO_r_struct_of_r_struct_of_r_struct_of_r_binaryANDr_int32ENDANDr_array_of_r_binaryENDANDr_int64ANDr_struct_of_o_int64ENDEND 2022-04-01 03:29:23 root: INFO: instruction count: 62: __C3622indexwriter.__m3655flush 2022-04-01 03:29:23 root: INFO: instruction count: 153: __C3622indexwriter.init 2022-04-01 03:29:23 root: INFO: instruction count: 7: __C3622indexwriter.setObjects 2022-04-01 03:29:23 root: INFO: instruction count: 33: __C3622indexwriter.close 2022-04-01 03:29:23 root: INFO: instruction count: 14: __C3622indexwriter.setPartitionIndex 2022-04-01 03:29:23 root: INFO: instruction count: 7: __C3622indexwriter.addPartitionRegion 2022-04-01 03:29:23 root: INFO: instruction count: 6: __C3657FSContainer. 2022-04-01 03:29:23 root: INFO: instruction count: 31: __C3657FSContainer.init_filesystem 2022-04-01 03:29:23 root: INFO: instruction count: 6: __C3657FSContainer. 2022-04-01 03:29:30 SparkContext: INFO: Starting job: collect at ContextRDD.scala:166 2022-04-01 03:29:30 DAGScheduler: INFO: Registering RDD 11 (mapPartitions at ContextRDD.scala:160) as input to shuffle 0 2022-04-01 03:29:30 DAGScheduler: INFO: Registering RDD 38 (mapPartitions at ContextRDD.scala:160) as input to shuffle 1 2022-04-01 03:29:30 DAGScheduler: INFO: Got job 4 (collect at ContextRDD.scala:166) with 12 output partitions 2022-04-01 03:29:30 DAGScheduler: INFO: Final stage: ResultStage 6 (collect at ContextRDD.scala:166) 2022-04-01 03:29:30 DAGScheduler: INFO: Parents of final stage: List(ShuffleMapStage 5, ShuffleMapStage 4) 2022-04-01 03:29:30 DAGScheduler: INFO: Missing parents: List(ShuffleMapStage 5, ShuffleMapStage 4) 2022-04-01 03:29:30 DAGScheduler: INFO: Submitting ShuffleMapStage 4 (MapPartitionsRDD[11] at mapPartitions at ContextRDD.scala:160), which has no missing parents 2022-04-01 03:29:30 MemoryStore: INFO: Block broadcast_31 stored as values in memory (estimated size 155.7 KB, free 5.6 GB) 2022-04-01 03:29:30 MemoryStore: INFO: Block broadcast_31_piece0 stored as bytes in memory (estimated size 55.2 KB, free 5.6 GB) 2022-04-01 03:29:30 BlockManagerInfo: INFO: Added broadcast_31_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 55.2 KB, free: 5.6 GB) 2022-04-01 03:29:30 SparkContext: INFO: Created broadcast 31 from broadcast at DAGScheduler.scala:1280 2022-04-01 03:29:30 DAGScheduler: INFO: Submitting 12 missing tasks from ShuffleMapStage 4 (MapPartitionsRDD[11] at mapPartitions at ContextRDD.scala:160) (first 15 tasks are for partitions Vector(0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11)) 2022-04-01 03:29:30 YarnScheduler: INFO: Adding task set 4.0 with 12 tasks 2022-04-01 03:29:30 DAGScheduler: INFO: Submitting ShuffleMapStage 5 (MapPartitionsRDD[38] at mapPartitions at ContextRDD.scala:160), which has no missing parents 2022-04-01 03:29:30 MemoryStore: INFO: Block broadcast_32 stored as values in memory (estimated size 185.1 KB, free 5.6 GB) 2022-04-01 03:29:30 MemoryStore: INFO: Block broadcast_32_piece0 stored as bytes in memory (estimated size 66.4 KB, free 5.6 GB) 2022-04-01 03:29:30 BlockManagerInfo: INFO: Added broadcast_32_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 66.4 KB, free: 5.6 GB) 2022-04-01 03:29:30 SparkContext: INFO: Created broadcast 32 from broadcast at DAGScheduler.scala:1280 2022-04-01 03:29:30 DAGScheduler: INFO: Submitting 12 missing tasks from ShuffleMapStage 5 (MapPartitionsRDD[38] at mapPartitions at ContextRDD.scala:160) (first 15 tasks are for partitions Vector(0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11)) 2022-04-01 03:29:30 YarnScheduler: INFO: Adding task set 5.0 with 12 tasks 2022-04-01 03:29:31 ExecutorAllocationManager: INFO: Requesting 1 new executor because tasks are backlogged (new desired total will be 1) 2022-04-01 03:29:33 YarnSchedulerBackend$YarnDriverEndpoint: INFO: Registered executor NettyRpcEndpointRef(spark-client://Executor) (172.23.70.80:48022) with ID 3 2022-04-01 03:29:33 ExecutorAllocationManager: INFO: New executor 3 has registered (new total is 1) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 0.0 in stage 4.0 (TID 1024, ip-172-23-70-80.ec2.internal, executor 3, partition 0, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 1.0 in stage 4.0 (TID 1025, ip-172-23-70-80.ec2.internal, executor 3, partition 1, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 2.0 in stage 4.0 (TID 1026, ip-172-23-70-80.ec2.internal, executor 3, partition 2, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 3.0 in stage 4.0 (TID 1027, ip-172-23-70-80.ec2.internal, executor 3, partition 3, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 4.0 in stage 4.0 (TID 1028, ip-172-23-70-80.ec2.internal, executor 3, partition 4, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 5.0 in stage 4.0 (TID 1029, ip-172-23-70-80.ec2.internal, executor 3, partition 5, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 6.0 in stage 4.0 (TID 1030, ip-172-23-70-80.ec2.internal, executor 3, partition 6, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 7.0 in stage 4.0 (TID 1031, ip-172-23-70-80.ec2.internal, executor 3, partition 7, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 8.0 in stage 4.0 (TID 1032, ip-172-23-70-80.ec2.internal, executor 3, partition 8, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 9.0 in stage 4.0 (TID 1033, ip-172-23-70-80.ec2.internal, executor 3, partition 9, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 10.0 in stage 4.0 (TID 1034, ip-172-23-70-80.ec2.internal, executor 3, partition 10, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 11.0 in stage 4.0 (TID 1035, ip-172-23-70-80.ec2.internal, executor 3, partition 11, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 0.0 in stage 5.0 (TID 1036, ip-172-23-70-80.ec2.internal, executor 3, partition 0, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 1.0 in stage 5.0 (TID 1037, ip-172-23-70-80.ec2.internal, executor 3, partition 1, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 2.0 in stage 5.0 (TID 1038, ip-172-23-70-80.ec2.internal, executor 3, partition 2, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 3.0 in stage 5.0 (TID 1039, ip-172-23-70-80.ec2.internal, executor 3, partition 3, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 4.0 in stage 5.0 (TID 1040, ip-172-23-70-80.ec2.internal, executor 3, partition 4, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 5.0 in stage 5.0 (TID 1041, ip-172-23-70-80.ec2.internal, executor 3, partition 5, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 6.0 in stage 5.0 (TID 1042, ip-172-23-70-80.ec2.internal, executor 3, partition 6, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 7.0 in stage 5.0 (TID 1043, ip-172-23-70-80.ec2.internal, executor 3, partition 7, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 8.0 in stage 5.0 (TID 1044, ip-172-23-70-80.ec2.internal, executor 3, partition 8, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 9.0 in stage 5.0 (TID 1045, ip-172-23-70-80.ec2.internal, executor 3, partition 9, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 10.0 in stage 5.0 (TID 1046, ip-172-23-70-80.ec2.internal, executor 3, partition 10, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:33 TaskSetManager: INFO: Starting task 11.0 in stage 5.0 (TID 1047, ip-172-23-70-80.ec2.internal, executor 3, partition 11, PROCESS_LOCAL, 8093 bytes) 2022-04-01 03:29:34 BlockManagerMasterEndpoint: INFO: Registering block manager ip-172-23-70-80.ec2.internal:40097 with 181.7 GB RAM, BlockManagerId(3, ip-172-23-70-80.ec2.internal, 40097, None) 2022-04-01 03:29:34 BlockManagerInfo: INFO: Added broadcast_31_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 55.2 KB, free: 181.7 GB) 2022-04-01 03:29:34 BlockManagerInfo: INFO: Added broadcast_32_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 66.4 KB, free: 181.7 GB) 2022-04-01 03:29:34 BlockManagerInfo: INFO: Added broadcast_11_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 35.6 KB, free: 181.7 GB) 2022-04-01 03:29:34 BlockManagerInfo: INFO: Added broadcast_5_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 35.6 KB, free: 181.7 GB) 2022-04-01 03:29:34 BlockManagerInfo: INFO: Added broadcast_9_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 109.0 B, free: 181.7 GB) 2022-04-01 03:29:34 BlockManagerInfo: INFO: Added broadcast_3_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 109.0 B, free: 181.7 GB) 2022-04-01 03:29:34 BlockManagerInfo: INFO: Added broadcast_8_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 109.0 B, free: 181.7 GB) 2022-04-01 03:29:35 BlockManagerInfo: INFO: Added broadcast_0_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 29.9 KB, free: 181.7 GB) 2022-04-01 03:29:36 BlockManagerInfo: INFO: Added broadcast_1_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 123.7 KB, free: 181.7 GB) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 11.0 in stage 4.0 (TID 1035) in 2320 ms on ip-172-23-70-80.ec2.internal (executor 3) (1/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 0.0 in stage 5.0 (TID 1036) in 2320 ms on ip-172-23-70-80.ec2.internal (executor 3) (1/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 11.0 in stage 5.0 (TID 1047) in 2319 ms on ip-172-23-70-80.ec2.internal (executor 3) (2/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 0.0 in stage 4.0 (TID 1024) in 2322 ms on ip-172-23-70-80.ec2.internal (executor 3) (2/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 8.0 in stage 4.0 (TID 1032) in 2338 ms on ip-172-23-70-80.ec2.internal (executor 3) (3/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 3.0 in stage 4.0 (TID 1027) in 2339 ms on ip-172-23-70-80.ec2.internal (executor 3) (4/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 10.0 in stage 4.0 (TID 1034) in 2339 ms on ip-172-23-70-80.ec2.internal (executor 3) (5/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 5.0 in stage 4.0 (TID 1029) in 2339 ms on ip-172-23-70-80.ec2.internal (executor 3) (6/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 6.0 in stage 4.0 (TID 1030) in 2339 ms on ip-172-23-70-80.ec2.internal (executor 3) (7/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 7.0 in stage 4.0 (TID 1031) in 2341 ms on ip-172-23-70-80.ec2.internal (executor 3) (8/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 9.0 in stage 4.0 (TID 1033) in 2343 ms on ip-172-23-70-80.ec2.internal (executor 3) (9/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 2.0 in stage 4.0 (TID 1026) in 2344 ms on ip-172-23-70-80.ec2.internal (executor 3) (10/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 4.0 in stage 4.0 (TID 1028) in 2348 ms on ip-172-23-70-80.ec2.internal (executor 3) (11/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 1.0 in stage 4.0 (TID 1025) in 2357 ms on ip-172-23-70-80.ec2.internal (executor 3) (12/12) 2022-04-01 03:29:36 YarnScheduler: INFO: Removed TaskSet 4.0, whose tasks have all completed, from pool 2022-04-01 03:29:36 DAGScheduler: INFO: ShuffleMapStage 4 (mapPartitions at ContextRDD.scala:160) finished in 5.368 s 2022-04-01 03:29:36 DAGScheduler: INFO: looking for newly runnable stages 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 1.0 in stage 5.0 (TID 1037) in 2358 ms on ip-172-23-70-80.ec2.internal (executor 3) (3/12) 2022-04-01 03:29:36 DAGScheduler: INFO: running: Set(ShuffleMapStage 5) 2022-04-01 03:29:36 DAGScheduler: INFO: waiting: Set(ResultStage 6) 2022-04-01 03:29:36 DAGScheduler: INFO: failed: Set() 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 10.0 in stage 5.0 (TID 1046) in 2360 ms on ip-172-23-70-80.ec2.internal (executor 3) (4/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 5.0 in stage 5.0 (TID 1041) in 2360 ms on ip-172-23-70-80.ec2.internal (executor 3) (5/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 7.0 in stage 5.0 (TID 1043) in 2361 ms on ip-172-23-70-80.ec2.internal (executor 3) (6/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 3.0 in stage 5.0 (TID 1039) in 2362 ms on ip-172-23-70-80.ec2.internal (executor 3) (7/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 2.0 in stage 5.0 (TID 1038) in 2362 ms on ip-172-23-70-80.ec2.internal (executor 3) (8/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 9.0 in stage 5.0 (TID 1045) in 2364 ms on ip-172-23-70-80.ec2.internal (executor 3) (9/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 6.0 in stage 5.0 (TID 1042) in 2364 ms on ip-172-23-70-80.ec2.internal (executor 3) (10/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 8.0 in stage 5.0 (TID 1044) in 2365 ms on ip-172-23-70-80.ec2.internal (executor 3) (11/12) 2022-04-01 03:29:36 TaskSetManager: INFO: Finished task 4.0 in stage 5.0 (TID 1040) in 2366 ms on ip-172-23-70-80.ec2.internal (executor 3) (12/12) 2022-04-01 03:29:36 YarnScheduler: INFO: Removed TaskSet 5.0, whose tasks have all completed, from pool 2022-04-01 03:29:36 DAGScheduler: INFO: ShuffleMapStage 5 (mapPartitions at ContextRDD.scala:160) finished in 5.393 s 2022-04-01 03:29:36 DAGScheduler: INFO: looking for newly runnable stages 2022-04-01 03:29:36 DAGScheduler: INFO: running: Set() 2022-04-01 03:29:36 DAGScheduler: INFO: waiting: Set(ResultStage 6) 2022-04-01 03:29:36 DAGScheduler: INFO: failed: Set() 2022-04-01 03:29:36 BlockManagerInfo: INFO: Removed broadcast_31_piece0 on ip-172-23-79-68.ec2.internal:36757 in memory (size: 55.2 KB, free: 5.6 GB) 2022-04-01 03:29:36 BlockManagerInfo: INFO: Removed broadcast_31_piece0 on ip-172-23-70-80.ec2.internal:40097 in memory (size: 55.2 KB, free: 181.7 GB) 2022-04-01 03:29:36 DAGScheduler: INFO: Submitting ResultStage 6 (MapPartitionsRDD[256] at mapPartitions at ContextRDD.scala:160), which has no missing parents 2022-04-01 03:29:37 ExecutorAllocationManager: INFO: Requesting 1 new executor because tasks are backlogged (new desired total will be 1) 2022-04-01 03:29:37 MemoryStore: INFO: Block broadcast_33 stored as values in memory (estimated size 148.5 MB, free 5.5 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece0 stored as bytes in memory (estimated size 4.0 MB, free 5.5 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece0 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece1 stored as bytes in memory (estimated size 4.0 MB, free 5.5 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece1 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece2 stored as bytes in memory (estimated size 4.0 MB, free 5.5 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece2 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece3 stored as bytes in memory (estimated size 4.0 MB, free 5.5 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece3 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece4 stored as bytes in memory (estimated size 4.0 MB, free 5.5 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece4 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece5 stored as bytes in memory (estimated size 4.0 MB, free 5.5 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece5 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece6 stored as bytes in memory (estimated size 4.0 MB, free 5.5 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece6 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece7 stored as bytes in memory (estimated size 4.0 MB, free 5.5 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece7 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece8 stored as bytes in memory (estimated size 4.0 MB, free 5.5 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece8 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece9 stored as bytes in memory (estimated size 4.0 MB, free 5.5 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece9 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece10 stored as bytes in memory (estimated size 4.0 MB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece10 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece11 stored as bytes in memory (estimated size 4.0 MB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece11 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece12 stored as bytes in memory (estimated size 4.0 MB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece12 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece13 stored as bytes in memory (estimated size 4.0 MB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece13 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece14 stored as bytes in memory (estimated size 4.0 MB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece14 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece15 stored as bytes in memory (estimated size 4.0 MB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece15 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece16 stored as bytes in memory (estimated size 4.0 MB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece16 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece17 stored as bytes in memory (estimated size 4.0 MB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece17 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece18 stored as bytes in memory (estimated size 4.0 MB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece18 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece19 stored as bytes in memory (estimated size 4.0 MB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece19 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece20 stored as bytes in memory (estimated size 4.0 MB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece20 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece21 stored as bytes in memory (estimated size 4.0 MB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece21 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece22 stored as bytes in memory (estimated size 4.0 MB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece22 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.6 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece23 stored as bytes in memory (estimated size 4.0 MB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece23 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.5 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece24 stored as bytes in memory (estimated size 4.0 MB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece24 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.5 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece25 stored as bytes in memory (estimated size 4.0 MB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece25 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 4.0 MB, free: 5.5 GB) 2022-04-01 03:29:38 MemoryStore: INFO: Block broadcast_33_piece26 stored as bytes in memory (estimated size 1940.1 KB, free 5.4 GB) 2022-04-01 03:29:38 BlockManagerInfo: INFO: Added broadcast_33_piece26 in memory on ip-172-23-79-68.ec2.internal:36757 (size: 1940.1 KB, free: 5.5 GB) 2022-04-01 03:29:38 SparkContext: INFO: Created broadcast 33 from broadcast at DAGScheduler.scala:1280 2022-04-01 03:29:38 DAGScheduler: INFO: Submitting 12 missing tasks from ResultStage 6 (MapPartitionsRDD[256] at mapPartitions at ContextRDD.scala:160) (first 15 tasks are for partitions Vector(0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11)) 2022-04-01 03:29:38 YarnScheduler: INFO: Adding task set 6.0 with 12 tasks 2022-04-01 03:29:38 TaskSetManager: WARN: Stage 6 contains a task of very large size (5223 KB). The maximum recommended task size is 100 KB. 2022-04-01 03:29:38 TaskSetManager: INFO: Starting task 0.0 in stage 6.0 (TID 1048, ip-172-23-70-80.ec2.internal, executor 3, partition 0, NODE_LOCAL, 5349039 bytes) 2022-04-01 03:29:38 TaskSetManager: INFO: Starting task 1.0 in stage 6.0 (TID 1049, ip-172-23-70-80.ec2.internal, executor 3, partition 1, NODE_LOCAL, 18116667 bytes) 2022-04-01 03:29:39 TaskSetManager: INFO: Starting task 2.0 in stage 6.0 (TID 1050, ip-172-23-70-80.ec2.internal, executor 3, partition 2, NODE_LOCAL, 23360869 bytes) 2022-04-01 03:29:39 TaskSetManager: INFO: Starting task 3.0 in stage 6.0 (TID 1051, ip-172-23-70-80.ec2.internal, executor 3, partition 3, NODE_LOCAL, 7953351 bytes) 2022-04-01 03:29:39 TaskSetManager: INFO: Starting task 4.0 in stage 6.0 (TID 1052, ip-172-23-70-80.ec2.internal, executor 3, partition 4, NODE_LOCAL, 17109373 bytes) 2022-04-01 03:29:39 TaskSetManager: INFO: Starting task 5.0 in stage 6.0 (TID 1053, ip-172-23-70-80.ec2.internal, executor 3, partition 5, NODE_LOCAL, 30024832 bytes) 2022-04-01 03:29:40 TaskSetManager: INFO: Starting task 6.0 in stage 6.0 (TID 1054, ip-172-23-70-80.ec2.internal, executor 3, partition 6, NODE_LOCAL, 35032057 bytes) 2022-04-01 03:29:40 TaskSetManager: INFO: Starting task 7.0 in stage 6.0 (TID 1055, ip-172-23-70-80.ec2.internal, executor 3, partition 7, NODE_LOCAL, 6587593 bytes) 2022-04-01 03:29:40 TaskSetManager: INFO: Starting task 8.0 in stage 6.0 (TID 1056, ip-172-23-70-80.ec2.internal, executor 3, partition 8, NODE_LOCAL, 3663565 bytes) 2022-04-01 03:29:40 TaskSetManager: INFO: Starting task 9.0 in stage 6.0 (TID 1057, ip-172-23-70-80.ec2.internal, executor 3, partition 9, NODE_LOCAL, 9346045 bytes) 2022-04-01 03:29:40 TaskSetManager: INFO: Starting task 10.0 in stage 6.0 (TID 1058, ip-172-23-70-80.ec2.internal, executor 3, partition 10, NODE_LOCAL, 7258515 bytes) 2022-04-01 03:29:40 TaskSetManager: INFO: Starting task 11.0 in stage 6.0 (TID 1059, ip-172-23-70-80.ec2.internal, executor 3, partition 11, NODE_LOCAL, 12697658 bytes) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece5 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.7 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece13 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.7 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece25 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.7 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece4 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.7 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece17 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.7 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece18 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.7 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece9 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.7 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece11 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.7 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece2 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.7 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece14 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.7 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece23 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.7 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece24 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.7 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.7 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece22 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.6 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece12 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.6 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece6 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.6 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece21 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.6 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece20 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.6 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece8 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.6 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece1 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.6 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece10 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.6 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece15 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.6 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece19 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.6 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece26 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 1940.1 KB, free: 181.6 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece3 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.6 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece16 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.6 GB) 2022-04-01 03:29:41 BlockManagerInfo: INFO: Added broadcast_33_piece7 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 4.0 MB, free: 181.6 GB) 2022-04-01 03:29:48 MapOutputTrackerMasterEndpoint: INFO: Asked to send map output locations for shuffle 1 to 172.23.70.80:48022 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_29_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 209.0 B, free: 181.6 GB) 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_28_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 109.0 B, free: 181.6 GB) 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_27_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 109.0 B, free: 181.6 GB) 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_26_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 114.0 B, free: 181.6 GB) 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_25_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 117.0 B, free: 181.6 GB) 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_24_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 109.0 B, free: 181.6 GB) 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_23_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 109.0 B, free: 181.6 GB) 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_22_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 109.0 B, free: 181.6 GB) 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_21_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 2.7 KB, free: 181.6 GB) 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_20_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 115.0 B, free: 181.6 GB) 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_19_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 109.0 B, free: 181.6 GB) 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_18_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 109.0 B, free: 181.6 GB) 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_17_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 109.0 B, free: 181.6 GB) 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_16_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 126.0 B, free: 181.6 GB) 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_15_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 1136.0 B, free: 181.6 GB) 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_14_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 109.0 B, free: 181.6 GB) 2022-04-01 03:29:48 BlockManagerInfo: INFO: Added broadcast_13_piece0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 109.0 B, free: 181.6 GB) 2022-04-01 03:29:48 MapOutputTrackerMasterEndpoint: INFO: Asked to send map output locations for shuffle 0 to 172.23.70.80:48022 2022-04-01 03:29:55 BlockManagerInfo: INFO: Added rdd_23_0 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 28.8 KB, free: 181.6 GB) 2022-04-01 03:29:55 BlockManagerInfo: INFO: Added rdd_23_10 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 48.9 KB, free: 181.6 GB) 2022-04-01 03:29:56 BlockManagerInfo: INFO: Added rdd_23_3 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 54.1 KB, free: 181.6 GB) 2022-04-01 03:29:56 BlockManagerInfo: INFO: Added rdd_23_11 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 60.0 KB, free: 181.6 GB) 2022-04-01 03:29:56 BlockManagerInfo: INFO: Added rdd_23_5 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 52.2 KB, free: 181.6 GB) 2022-04-01 03:29:57 BlockManagerInfo: INFO: Added rdd_23_1 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 60.4 KB, free: 181.6 GB) 2022-04-01 03:29:57 BlockManagerInfo: INFO: Added rdd_23_8 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 64.9 KB, free: 181.6 GB) 2022-04-01 03:29:57 BlockManagerInfo: INFO: Added rdd_23_9 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 63.4 KB, free: 181.6 GB) 2022-04-01 03:29:57 BlockManagerInfo: INFO: Added rdd_23_7 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 68.3 KB, free: 181.6 GB) 2022-04-01 03:29:58 BlockManagerInfo: INFO: Added rdd_23_4 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 59.4 KB, free: 181.6 GB) 2022-04-01 03:29:59 BlockManagerInfo: INFO: Added rdd_23_2 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 76.3 KB, free: 181.6 GB) 2022-04-01 03:29:59 BlockManagerInfo: INFO: Added rdd_23_6 in memory on ip-172-23-70-80.ec2.internal:40097 (size: 78.0 KB, free: 181.6 GB) 2022-04-01 03:33:09 YarnScheduler: INFO: Cancelling stage 6 2022-04-01 03:33:09 YarnScheduler: INFO: Killing all running tasks in stage 6: Stage cancelled 2022-04-01 03:33:09 YarnScheduler: INFO: Stage 6 was cancelled 2022-04-01 03:33:09 DAGScheduler: INFO: ResultStage 6 (collect at ContextRDD.scala:166) failed in 212.736 s due to Job 4 cancelled as part of cancellation of all jobs 2022-04-01 03:33:09 DAGScheduler: INFO: Job 4 failed: collect at ContextRDD.scala:166, took 218.413782 s 2022-04-01 03:33:09 root: ERROR: error while applying lowering 'InterpretNonCompilable' 2022-04-01 03:33:09 root: INFO: The exact same exception object, org.apache.spark.SparkException: Job 4 cancelled as part of cancellation of all jobs, was thrown by both the consumer and the close method. I will throw the original. 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 127 2022-04-01 03:33:09 BlockManagerInfo: INFO: Removed broadcast_32_piece0 on ip-172-23-70-80.ec2.internal:40097 in memory (size: 66.4 KB, free: 181.6 GB) 2022-04-01 03:33:09 BlockManagerInfo: INFO: Removed broadcast_32_piece0 on ip-172-23-79-68.ec2.internal:36757 in memory (size: 66.4 KB, free: 5.5 GB) 2022-04-01 03:33:09 SparkContext: INFO: Invoking stop() from shutdown hook 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 124 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 107 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 146 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 137 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 114 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 110 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 105 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 123 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 149 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 128 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 135 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 142 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 115 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 150 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 129 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 118 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 145 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 139 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 112 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 125 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 131 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 148 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 132 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 101 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 106 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 144 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 130 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 121 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 136 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 119 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 138 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 147 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 126 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 111 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 113 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 117 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 141 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 134 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 143 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 116 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 109 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 104 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 103 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 122 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 133 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 140 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 108 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 120 2022-04-01 03:33:09 ContextCleaner: INFO: Cleaned accumulator 102 2022-04-01 03:33:09 AbstractConnector: INFO: Stopped Spark@159c2bd6{HTTP/1.1, (http/1.1)}{0.0.0.0:4040} 2022-04-01 03:33:09 SparkUI: INFO: Stopped Spark web UI at http://ip-172-23-79-68.ec2.internal:4040 2022-04-01 03:33:09 YarnClientSchedulerBackend: INFO: Interrupting monitor thread 2022-04-01 03:33:09 YarnClientSchedulerBackend: INFO: Shutting down all executors 2022-04-01 03:33:09 YarnSchedulerBackend$YarnDriverEndpoint: INFO: Asking each executor to shut down 2022-04-01 03:33:09 SchedulerExtensionServices: INFO: Stopping SchedulerExtensionServices (serviceOption=None, services=List(), started=false) 2022-04-01 03:33:09 YarnClientSchedulerBackend: INFO: Stopped 2022-04-01 03:33:09 MapOutputTrackerMasterEndpoint: INFO: MapOutputTrackerMasterEndpoint stopped! 2022-04-01 03:33:09 MemoryStore: INFO: MemoryStore cleared 2022-04-01 03:33:09 BlockManager: INFO: BlockManager stopped 2022-04-01 03:33:09 BlockManagerMaster: INFO: BlockManagerMaster stopped 2022-04-01 03:33:09 OutputCommitCoordinator$OutputCommitCoordinatorEndpoint: INFO: OutputCommitCoordinator stopped! 2022-04-01 03:33:09 SparkContext: INFO: Successfully stopped SparkContext 2022-04-01 03:33:09 ShutdownHookManager: INFO: Shutdown hook called 2022-04-01 03:33:09 ShutdownHookManager: INFO: Deleting directory /mnt/tmp/spark-69d8adea-ce9a-493b-b143-1e5e110b4cb4 2022-04-01 03:33:09 ShutdownHookManager: INFO: Deleting directory /mnt/tmp/spark-69d8adea-ce9a-493b-b143-1e5e110b4cb4/pyspark-4cc6ebb1-2719-4370-8980-f317b3c53f46 2022-04-01 03:33:09 ShutdownHookManager: INFO: Deleting directory /mnt/tmp/spark-5670713f-e4e1-4a1a-91af-90bd597d0c01