Could an annotation module using snpEff be implemented in Hail? We find it runs faster than VEP and much easier to install. The software is found here:SnpEff and SnpSift
There is a general effort to make it easier to hook hail up into arbitrary command line programs like this or VEP. We likely won’t ever build a snpEff function the way we have with VEP, but it should get to a point where you can call some general purpose function to stream data to an outside command line tool.
Thanks! That feature would be very useful. Is there a estimated timeline for this type of functionality? This sounds similar to what GLOW is doing with their pipe transformer feature which is the other approach I was looking at trying with SnpEff.