I’m trying to call de novo events using hail.methods.de_novo. In the example below (copied from the hail website), I’m wondering about the format for the gnomadFreq.tsv file specified on the second line. What should this file look like? Thanks so much.

Thank you! Is the file used in the example available (or something similar?).

Could I annotate the rows of the matrix table with the population alternate allele frequency priors and use that for the pop_frequency_prior parameter?

Could I annotate the rows of the matrix table with the population alternate allele frequency priors and use that for the pop_frequency_prior parameter?